Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

EPA FORM 6300-4

1. Company Name and Address

BASF CORPORATION

26 DAVIS DRIVE, P.O. Box 13528

RESEARCH TRIANGLE PARK, NC 277093528

2600 - Sethoxydim

Chemical # and Name: 121001

Sethoxydim

GENERIC

ID # GDCI-121001-1537

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page 1 of 1

7969-294

7969-56

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A

N/A

N/A

N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

BASF CORPORATION

26 DAVIS DRIVE, P.O. Box 13528

RESEARCH TRIANGLE PARK, NC 277093528

Nontarget Plant Protection Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

850.4100

850.4150

850.1300

850.1350

850.1400

850.2100

850.3030

850.3040

Seedling Emergence and Seedling Growth

Vegetative Vigor

Daphnid chronic toxicity test

Mysid chronic toxicity test

Fish early-life stage toxicity test

Avian acute oral toxicity test

Honey bee toxicity of residues on foliage

Field testing for pollinators

2600 - Sethoxydim

Chemical # and Name: 121001

Sethoxydim

GENERIC

ID # GDCI-121001-1537

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

TEP

TEP

TGAI

TGAI

TGAI

TGAI

TEP

TEP

12

12

12

12

12

24

12

24

Page 1 of 

(5, 8, 10, 18, 

24)

(5, 7, 9, 18, 

24)

(23)

(22)

(19)

(20)

(1)

(2, 3)

N

N

N

N

N

Y

N

Y

2
Date

OMB Approval 2070-0174 

EPA FORM 6300-3

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

BASF CORPORATION

26 DAVIS DRIVE, P.O. Box 13528

RESEARCH TRIANGLE PARK, NC 277093528

SS-1256

SS-1257

SS-1316

SS-1342

SS-1344

SS-1345

SS-1346

Acute oral toxicity--honeybee adult

Acute oral toxicity--honeybee larvae

Field trial of residues in pollen and nectar

Semi Field Testing for Pollinators (Tunnel or Colony 

Feeding Studies)

Chronic Oral Toxicity - Larval Honeybee

Aquatic Vascular Plant Toxicity Study with a Grass 

Species

Chronic Oral Toxicity - Adult Honeybee

2600 - Sethoxydim

Chemical # and Name: 121001

Sethoxydim

GENERIC

ID # GDCI-121001-1537

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

T,K,R

TGAI

TGAI

TEP

TEP

TGAI

DEGR

TGAI

12

12

24

24

12

12

12

Page 2 of 

(6)

(12, 14)

(13, 21)

(3, 15, 16)

(4, 14)

(17)

(11)

N

N

Y

Y

Y

Y

Y

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

2600 - Sethoxydim

GDCI-121001-1537

1

2

3

4

5

6

7

8

9

10

11

12

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

USEPA. 2012b. Honey Bee Toxicity of Residues on Foliage. Ecological Effects Test Guidelines OCSPP 850.3030. EPA 712-C-018. Web. http://www.regulations.gov/#!documentDetail;D=EPA-HQOPPT-2009-0154-0017

The study with the honey bee is being required consistent with the pesticide risk assessment for bees. The registrant should consult both the white paper and the pollinator risk assessment

guidance, and work with the agency to develop the design of the field study. A protocol must be submitted for review prior to study initiation. Guidance on ecological testing for invertebrates

with the honey bee and the agency's risk assessment process for bees can be found at:http://www2.epa.gov/pollinator-protection/how-we-assess-risks-pollinators.

The need for a higher tier test for pollinators (i.e., either a field-feeding test or a tunnel test) will be determined based upon lower-tiered tests and/or other lines of evidence, and the need for a 

refined pollinator risk assessment.

The November 2013 draft OECD protocol for a honey bee brood test using repeated doses may be used for this study. Please see

http://www.oecd.org/env/ehs/testing/Draft_GD_honeybees_rep_exp_for_2nd_CR_25_November_2013.pdf for details.

Testing with the highest maximum single application rate is required.

See the OECD 213: OECD Guidelines for the Testing of Chemicals. Honeybees, Acute Oral Toxicity Test. 213. http://lysander.sourceoecd.org/vl=5988235/cl=12/nw=1/rpsv/cgibin/

fulltextew.pl?prpsv=/ij/oecdjournals/1607310x/v1n2/s14/p1.idx

Refer to public draft guideline 850.4250 for guidance on Tier II vegetative vigor testing.

Refer to public draft guideline 850.4225 for guidance on Tier II seedling emergence testing.

On June 27, 2012, EPA announced certain revisions in harmonized guideline series 850 .. Ecological Effects Tests .. including renumbering such as from OPPTS 850.4150 (Vegetative vigor) to 

OCSPP 850.4150 (Vegetative vigor) and from OPPTS 850.5400 (Algal toxicity) to OCSPP 850.4500 (Algal toxicity) and OCSPP 850.4550 (Cyanobacteria toxicity). See Final Test Guidelines; 

OCSPP 850 Series; Notice of Availability. 77 FR 38282, June 27, 2012. http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT-2009-0154-0028

On June 27, 2012, EPA announced certain revisions in harmonized guideline series 850 .. Ecological Effects Tests .. including removal of the Tier designation on 850.4100 (Seedling Emergence 

and Seedling Growth), 850.4150 (Vegetative Vigor), 850.4300 (Terrestrial Plants Field Study), 850.4400 (Aquatic Plant Toxicity Test Using Lemna Spp.), 850.4450 (Aquatic Plants Field Study) 

and 850.5400 (Algal Toxicity). See Final Test Guidelines; OCSPP 850 Series; Notice of Availability. 77 FR 38282, June 27, 2012. http://www.regulations.gov/#!documentDetail;D=EPA-HQ-OPPT2009-0154-0028

OECD is developing study guidance for assessing the chronic (10-day) oral toxicity to the honey bee. Discussion of the study design elements for the 10-day adult toxicity test can be found in 

Appendix O of the European Food Safety Authority (EFSA) guidance document: EFSA. Guidance on the risk assessment of plant protection products on bees (Apis mellifera, Bombus spp. and 

solitary bees. EFSA Journal 2013;11(7):3295, 266 pp. doi:10.2903/j.efsa.2013.3295. Available online: www.efsa.europa.eu/efsajournal or at:

http://www.efsa.europa.eu/en/efsajournal/doc/3295.pdf

OECD Test Guideline 237 may be used to develop a protocol for this study (OECD. 2013 Guidelines for Testing Chemicals. Honey bee (Apis mellifera) larval toxicity test, single exposure.) See:

http://www.oecd-ilibrary.org/environment/test-no-237-honey-bee-apis-mellifera-larval-toxicity-test-single-exposure_9789264203723-en

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

K - Residential

R - Agricultural premises and equipment

T - Commercial, institutional and industrial premises

and equipment

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

2600 - Sethoxydim

GDCI-121001-1537

13

14

15

16

17

18

19

20

21

22

23

24

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

Measurements of residues in the pollen/nectar are needed based upon lower-tiered tests and/or other lines of evidence, and the need for a refined pollinator risk assessment.

In some cases, information pertaining to acute toxicity to honey bee larvae may be obtained with the chronic honey bee larvae test thereby negating the need for separate acute and chronic 

larval toxicity tests.

Formal guidelines for semi-field tests do not yet exist; however, information that can help guide the development of either a semi-field tunnel test protocol can be found at OECD 75, see: OECD. 

2007. Series on Testing and Assessment Number 75. Guidance document on the honey bee (Apis mellifera L.) brood test under semi-field conditions. Environmental Directorate Joint Meeting of 

the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology. ENV/JM/MONO(2007)22. 31-Aug-2007.

http://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/jm/mono(2007)22&doclanguage=en.

For field-feeding studies see: Oomen et al. 1992: Oomen, P. A. A. DeRuijter and J. Van der Steen. 1992. Method for honey bee brood feeding tests with insect growth-regulating insecticides. 

Bul OEPP/EPPO Bulletin 22: 613, 616.

Data from this study are required solely for Sulfone (the terminal degradate, M2-SO2).

Data are required for six species of dicots from at least four families, one species of which is soybean (Glycine max). Data are required for four species of monocots from at least two families,

one species which is corn (Zea mays). At least one of either the monocot or dicot species must be a root crop.

Data are preferred on sheepshead minnow (Cypinodon variegatus).

Conducted with a passerine species.

A study protocol must be submitted to, and reviewed by EPA, prior to study initiation. The following elements could be considered when developing study protocol(s) for the monitoring of 

residues in pollen/nectar.

- Consideration of the range of application methods and environmental conditions (e.g., soil and hydric regimes) that the target crop(s) may be under.

- Consideration of the attractiveness of the selected crop to pollinators

- Consideration of a collection schedule sufficient to allow for an understanding of the character of residues, in the pollen/nectar and/or plant tissues, over time.

- Consideration of data sufficient to determine whether residues of the active ingredient and/or degradation product(s) accumulates in soil and is/are bioavailable for plant to uptake in a following

planting, and therefore result in potential exposure to pollinators.

- Consideration of the market proportion of the selected target crop(s).

A saltwater invertebrates life-cycle study is required.

A freshwater invertebrate life-cycle study is required.

A Tier II study is required. A Tier I plant study may be conducted in lieu of a Tier II study with the understanding that any adverse effects observed by the Tier I study would necessitate conduct

and submission of a Tier II study as well. The purpose of a Tier II study is to establish both a definitive No Observed Adverse Effect Concentration (NOAEC), or alternatively, a concentration at 

which there is a 5% observed inhibition effect (IC05), to be used in a risk assessment and effects determination for endangered or threatened species (listed species), and a definitive IC25 

(concentration at which there is a 25% observed inhibition effect) for assessing risk to non-listed non-target plants. If any adverse effects are observed in a Tier I study and neither a definitive 

NOAEC nor a definitive IC05 value is available, then the Agency may have to presume in its effects determination, that sethoxydim "may affect" and is likely to adversely affect listed plant 

species.

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 2600 - Sethoxydim

Page: 1 of 1

7969 BASF CORPORATION

Co. Nr. Company Name Agent For Company

26 DAVIS DRIVE, P.O. Box 13528

Address City ZIP

RESEARCH TRIANGLE PARK 277093528

OMB Approval 2070-0174

State

NC

 DCI Number: GDCI-121001-1537