Initial to indicate certification as to information on this page (full text of certification is on page one). Date INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary. 2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product Registration 5. I wish to cancel this product registration voluntarily 6. Generic Data 7. Product Specific Data 6a. I am claiming a Generic Data Exemption because I obtain the active ingredient from the source EPA registration number listed below. 6b. I agree to satisfy Generic Data Requirements as indicated on the attached form entitled "Requirements Status and Registrant's Response." 7a. My product is an MUP and I agree to satisfy the MUP requirement on the attached form entitled "Requirements Status and Registrant's Response." 7b. My product is an EUP and I agree to satisfy the EUP requirement on the attached form entitled "Requirements Status and Registrant's Response." OMB Approval 2070-0174

1. Company Name and Address N/A - Fluazinam Chemical # and Name: 129098 Fluazinam 12-Aug-2011 GENERIC ID # GDCI-129098-875 

### United States Environmental Protection Agency

Washington, D.C. 20460 DATA CALL-IN RESPONSE 1 Page of 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law. Signature and Title of Company's Authorized Representative ______________________________________________________ 10. Name of Company N/A N/A

9. Date

11. Phone NumberInitial to indicate certification as to information on this page (full text of certification is on page one) 13. Phone Number 10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.
12. Name of Company 11. Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

Environmental Fate Data Requirements (Conventional Chemical)

Nontarget Plant Protection Data Requirements (Conventional Chemical)

Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical) 835.6100 835.6200

850.4225 850.4400 850.5400

850.1350 Terrestrial field dissipation

Aquatic field dissipation

Seedling emergence, Tier II Aquatic plant toxicity test using Lemna spp. Tiers I and II Algal toxicity, Tiers 1 and II

Mysid chronic toxicity test N/A - Fluazinam Chemical # and Name: 129098 Fluazinam 12-Aug-2011 GENERIC ID # GDCI-129098-875

A A

A A A

A TEP TEP

TEP EP; PAI; TGAI EP; PAI; TGAI

TGAI 12 12

12 12 12

12 1 of Page

(22) (21)

(5, 7, 8, 9, 26) (4, 7) (6, 7, 8)

(14, 16, 19, 24) N N

N N N

N 2Date OMB Approval 2070-0174 

### United States Environmental Protection Agency

Washington, D.C. 20460 REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline Requirement Number 5. Study Title Progress Reports



### 2 3 1 6. Use

Pattern 7. Test Substance 8. Time Frame (Months) 9. Registrant

Response P R O T O C O L 1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Terrestrial and Aquatic Nontarget Organisms Data Requirements (Conventional Chemical)

Toxicology Data Requirements (Conventional Chemical) 850.1400 850.2100

870.3465 870.7800

850.1790 Fish early-life stage toxicity test

Avian acute oral toxicity test

90-day inhalation toxicity Immunotoxicity
Chironomid Sediment Toxicity Test N/A - Fluazinam Chemical # and Name: 129098 Fluazinam 12-Aug-2011 GENERIC ID # GDCI-129098-875

A A

A A

A TGAI EP; PAI; TGAI

TGAI TGAI

EP; PAI; TGAI 12 12

24 12

12 2 of Page

(13, 15, 18) (10, 11, 12, 23)
(3, 20)

(1, 2, 17, 25) N

Y

N N

N 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS N/A - Fluazinam GDCI-129098-875

1 2 3 4 5 6 7 8 9 10

11 12 13 14 15

16

17 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

The test substance should be the technical grade active ingredient. Sediment testing with estuarine/marine test species is required if the product is intended for direct application to the estaurine or marine environment or the product is expected to enter this environment in concentrations which the Agency believes to be significant, either by runoff or erosion, because of its expected use or mobility pattern. Required if there is the likelihood of significant repeated inhalation exposure to the pesticide as a gas, vapor, or aerosol. Required if an aquatic species exhibits a 50 percent or greater detrimental effect in Tier 1. Required for known phytotoxicants such as herbicides, desiccants, defoliants, and plant growth regulators. Not required for known phytotoxicants. Not required for contained pesticide treatments such as bait boxes and pheromone traps unless adverse effects reports are received by the Agency. Not required for aquatic residential uses. Generally not required for granular formulations, but may be required on a case-by-case basis. For greenhouse and indoor end-use products, data using the TGAI are required to support manufacturing use products to be reformulated or to support these same end-use products when there is no registered manufacturing use product. For Avian acute oral data are not required for liquid formulations for greenhouse and indoor uses. The study is not required if there is no potential for environmental exposure. Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile liquid, a highly reactive solid, or a highly corrosive material. Data are required on one passerine species. Data are required on one estaurine/marine species, preferably the sheepshead minnow (Cypinodon variegatus). Data are required on one estaurine/marine invertebrate species. Data are required on marine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; (b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days). Data are required on estuarine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; (b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days). Data are required if: Case # and Name: DCI Number: 1 Page: of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement. Use Categories Key: A - Terrestrial food crop 2

### United States Environmental Protection Agency Washington, D.C. 20460 FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS N/A - Fluazinam GDCI-129098-875

18 19 20 21 22 23 24 25 26 Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

i. The estimated environmental concentration (EEC) in sediment is>0.1 of the acute LC50/EC50values and ii. The half-life of the pesticide in the sediment is>10 days in either the aerobic soil or aquatic metabolism studies and if any of the following conditions exist: A. The soil partition coefficient (Kd) is¿50. B. The log Kow is¿3. C. The Koc¿1,000. iii. Registrants must consult with the Agency on appropriate test protocols prior to designing the study. Data are generally not required for outdoor residential uses, other than turf, unless data indicate that pesticides residues from the proposed use(s) can enter waterways. Data are generally not required for outdoor residential uses, other than turf, unless data indicate that pesticide residues from the proposed use(s) can potentially enter waterways. Based on estimates of the magnitude and duration of human exposure, studies of shorter duration, a 28-day study would be sufficient to satisfy this requirement. An environmental chemistry method and associated independent laboratory validation for fluazinam residues of concern in water and sediment are required. An entire aquatic field dissipation study is not required. An environmental chemistry method and associated independent laboratory validation for fluazinam residues of concern in soil are required. An entire field dissipation study is not required. A protocol will need to be provided to EPA for review prior to starting toxicity testing. A chronic study submitted for estuarine/marine aquatic invertebrates in response to the RED DCI was classified as supplemental. This chronic mysid study may be upgraded from supplemental if additional raw data are provided. A chironomid study submitted to the Agency has been classified as supplemental. This study may be upgraded from supplemental if additional raw data is provided. A Tier I study may be conducted initially. However, Tier II testing is required if a tested terrestrial species exhibits a 25 percent or greater detrimental effect in the Tier I study. When a Tier II testing is conducted, the test species should be the species that showed detrimental efects in the Tier I testing. Case # and Name: DCI Number: 2 Page: of 2

### United States Environmental Protection Agency Washington, D.C. 20460 LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE N/A - Fluazinam Case # and Name: 1 Page: of 1

71512 ISK BIOSCIENCES CORPORATION Co. Nr. Company Name Agent For Company 7470 AUBURN ROAD, SUITE A Address City ZIP CONCORD 44077 OMB Approval 2070-0174

State OH DCI Number: GDCI-129098-875

# LINKS TO FORMS: The pesticide registration forms that are listed below can be found at: http://www.epa.gov/opprd001/forms/ Link to C onfidential Statement of Formula and Instructions (Form # 8570 -4 

# ) http://www.epa.gov/opprd001/forms/8570 - 4.pdf C ertification of Attempt to Enter Into an Agreement With Registrants for Development of Data (Form # 8570 - 32 

# ) http://www.epa.gov/opprd001/forms/8570 - 32.pdf
C ertification With Respect to Citation of Data (Form # 8570 - 34 

# ) http://www.epa.gov/opprd001/forms/8570 - 34.pdf