**Exhibit      31.1**

**CERTIFICATION**

|  | 1. | I                have reviewed this annual report on Form 10-K of the Company for                the                fiscal year ended January 31, 2007; |
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|  | 2. | Based                on my knowledge, this annual report does not contain any untrue statement                of a material fact or omit to state a material fact necessary in                order to                make the statements made, in light of the circumstances under which                such                statements were made, not misleading with respect to the period covered                by                this report; |
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|  | 3. | Based                on my knowledge, the financial statements, and other financial information                included in this report, fairly present in all material respects                the                financial condition, results of operations and cash flows of the                Company                as of, and for, the period presented in this report;  |
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|  | 4. | The                Company’s other certifying officer and I are responsible for establishing                and maintaining disclosure controls and procedures (as defined in                Exchange                Act Rules 13a-15(e) and 15d-15(e) for the Company and we                have: |
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|  | (a) | designed                such disclosure controls and procedures, or caused such disclosure                controls and procedures to be designed under our supervision, to                ensure                that material information relating to the Company, including its                consolidated subsidiaries, is made known to us by others within those                entities, particularly during the period in which this report was                being                prepared; |
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|  | (b) | evaluated                the effectiveness of the Company’s disclosure controls and procedures and                presented in this report our conclusions about the effectiveness                of the                disclosure controls and procedures, as of the end of the period covered                by                this report based on such evaluation;                and |
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|  | (c) | disclosed                in this report any change in the Company’s internal control over financial                reporting that occurred during the Company’s most recent fiscal quarter                that has materially affected, or is reasonably likely to materially                affect                the Company’s internal control over financial reporting;                and |
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|   | 5. | The                Company’s other certifying officer and I have disclosed, based on our most                recent evaluation, to the Company’s auditors and the audit committee of                the Company’s board of directors: |
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|  | (a) | all                significant deficiencies and material weaknesses in the design or                operation of internal control over financial reporting which are                reasonably likely to adversely affect the Company’s ability to record,                process, summarize and report financial information;                and |
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|  | (b) | any                fraud, whether or not material, that involves management or other                employees who have a significant role in the Company’s internal control                over financial reporting. |
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| Dated:                April 30, 2007 | /s/                George G. Usher             |
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|                                 | Chief                Executive Officer         |
|                                 | Polydex                Pharmaceuticals Limited |

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