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Exhibit 31.1 CERTIFICATION

I, George G. Usher, do hereby certify that:

|1. | I have reviewed this annual report on Form 10-K of the
      Company for the fiscal year ended January 31, 2010;                                                                                                                                                                                                                                          
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|2. | Based on my knowledge, this annual report does not
      contain any untrue statement of a material fact or omit to state a
      material fact necessary in order to make the statements made, in light of
      the circumstances under which such statements were made, not misleading
      with respect to the period covered by this report;        
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|3. | Based on my knowledge, the financial statements, and
      other financial information included in this report, fairly present in all
      material respects the financial condition, results of operations and cash
      flows of the Company as of, and for, the period presented in this
      report;                                               
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|4. | The Companys other certifying officer and I are
      responsible for establishing and maintaining disclosure controls and
      procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e) and
      internal control over financial reporting (as defined in Exchange Act
      Rules 13a-15(f) and 15d-15(f)) for the Company and we
  have:

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| | (a) | designed such disclosure controls and procedures, or
      caused such disclosure controls and procedures to be designed under our
      supervision, to ensure that material information relating to the Company,
      including its consolidated subsidiaries, is made known to us by others
      within those entities, particularly during the period in which this report
      was being prepared;
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| | (b) | designed such internal control over financial reporting,
      or caused such internal control over financial reporting to be designed
      under our supervision, to provide reasonable assurance regarding the
      reliability of financial reporting and the preparation of financial
      statements for external purposes in accordance with generally accepted
      accounting principles      
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| | (c) | evaluated the effectiveness of the Companys disclosure
      controls and procedures and presented in this report our conclusions about
      the effectiveness of the disclosure controls and procedures, as of the end
      of the period covered by this report based on such evaluation;
  and                                                                                                      
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| | (d) | disclosed in this report any change in the Companys
      internal control over financial reporting that occurred during the
      Companys most recent fiscal quarter (the Companys fourth fiscal quarter
      in the case of an annual report) that has materially affected, or is
      reasonably likely to materially affect the Companys internal control over
      financial reporting.      

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|5. | The Companys other certifying officer and I have
      disclosed, based on our most recent evaluation, to the Companys auditors
      and the audit committee of the Companys board of
  directors:

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| | (a) | all significant deficiencies and material weaknesses in
      the design or operation of internal control over financial reporting which
      are reasonably likely to adversely affect the Companys ability to record, process,
      summarize and report financial information; and

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| | (b) | any fraud, whether or not material, that involves
      management or other employees who have a significant role in the Companys
      internal control over financial reporting.

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|Dated: May 3, 2010 | /s/ George G. Usher            
|                   | Chief Executive Officer        
|                   | Polydex Pharmaceuticals Limited



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