EXHIBIT 31 (c)

CERTIFICATIONS

In connection
with Amendment No. 1 to the Annual Report on Form 10-K of Enzo Biochem, Inc. (the
Company) for the fiscal year ended July 31, 2009 as filed with the Securities
and Exchange Commission on the date hereof, I, Elazar Rabbani, Ph.D., Chief
Executive Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as
adopted pursuant to § 302 of the Sarbanes-Oxley Act of 2002, that:

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|1. | I have
 reviewed this Amendment No. 1 to the Annual Report on Form 10-K of Enzo
 Biochem, Inc.                                                                                                                                                                                                                
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|2. | Based on my
 knowledge, this report does not contain any untrue statement of a material
 fact or omit to state a material fact necessary to make the statements made,
 in light of the circumstances under which such statements were made, not
 misleading with respect to the period covered by this report;
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|3. | [Intentionally omitted]
 *                                                                                                                                                                                                                                                                                    
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|4. | [Intentionally omitted]
 *                                                                                                                                                                                                                                                                                    
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|5, | [Intentionally omitted]
 *                                                                                                                                                                                                                                                                                    

|                         |     |                                       
|------------------------ | --- | --------------------------------------
|Date:
 November 25, 2009 |     |                                       
|                         | By: | /s/ Elazar
 Rabbani, Ph.D.            
|                         |     |                                       
|                         |     | Elazar
 Rabbani, Ph.D.                
|                         |     | Chairman of
 the Board of Directors,  
|                         |     | Chief
 Executive Officer and Secretary

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| | * Paragraphs
 3 through 5 are included in Exhibit 31(a) to the Annual Report on Form 10-K.
     See Note 16 to the Exhibits

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