### June 24, 2013 UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON D.C. , 20460

OFF I CE OF CHEMICAL SAFETY AND POLLUTION PREVENTION



### MEMORANDUM

SUBJECT:

TO:

FROM:

THROUGH: Drinking Water Assessment to Assess Flonicamid Use on Alfalfa and Clover Grown for Seed, Fruiting Vegetables, Mint

, Tree Nuts, and the Expansion to the Full Crop Group for Pome Fruit and Stone Fruit. PC Code: 128016; DP Barcode: 408552, 408555



### Barbara Madden, Team Leader 05 Sidney Jackson, Risk Manager Reviewer Risk Integration Minor Use, and E mergency Response Branch Registration Division



### James A. 

### Hetrick, Ph.D., Senior Science

# Advis~ 

# t{.l:/et:. './-

Environmental Risk Branch 3 /. ( Environmental Fate and Effects Division (7507P)

## ~**L~** L}



### Dana Spatz, Branch

# ch~~ 

# bI-z. 'i

# I~ 13

Rosanna Louie-Juzwiak, RAPL

# ~~>@ Environmental Risk Branch 3 ' [ 

### 'L'f 

# /u,

Environmental Fate and Effects Division (7507P) 

## '3

EXECUTIVE SUMMARY



### IR-4 is seeking the addition of new uses of flonicamid on alfalfa and clover for seed, mint, to expand to the full crop group for pome and stone fruits, and to increase application rate on fruiting vegetables offlonicamid [BeleafrM-50SG Insecticide (EPA Reg. No. 71512-10) and Flonicamid 50WG (EPA Reg. No. 71512-9)] for the control of aphids, leafhoppers, whitefly, and plant bugs. Also considered in this assessment is the proposed use on tree nuts, which was requested by the registrant, ISK Biosciences. The proposed new use requests ground, aerial, or chemigation spray applications of flonicamid at a maximum seasonal application rate of 0.267 lb ai/A.

The drinking water assessment was conducted using both a parent only exposure , and a total toxic residue (TTR) approach, which considers the parent compound and its major degradates of

concern previously identified by HED 1. The predicted concentrations of flonicamid total toxic residues for the proposed uses, except cranberry, are lower than estimated drinking water

I Total toxic residues include 4-tr i fluoromethylnicotinic acid (TFNA), 4-trifluoromethylnictinamide (TFNA-AM), 6-hydro-4-trifluoromethylnicotinic acid (TFNA-OH)

, N-(4-trifluoromethylnicot i noyl)glycine (TFNG), and N-(4- trifluoromethylnicotinoyl )glycinamide (TFNG-AM).

### 2 concentrations (EDWC) in pr evious drinking water assessmen ts (Table 3). The EDWCs for cranberry were estimated using the Tier 1 ri ce model which does not account for dilution and degradation. Because flonicamid and its degrad ation products degrade ra pidly in aerobic soil (t 1/2 

### =5.2 days), the EDWCs for cranberry are expect ed to be highly conservative and, therefore, are expected to greatly exaggerate the Tier 1 screening EDWCs (94.93 μg/L for single application and 285.44 μg/L for annual application rate). EFED, therefore, recommends HED use the EDWCs from PRZM-GW. The concentratio n of total toxic residues of flonicamid (flonicamid TTR) in ground wat er is predicted to not exceed 15.9 μg/L for the daily peak and 9.92 μg/L for the 30 year annual average. These concentrations are associated with proposed increase application rate of 0.133 lb a.i./A on fruiting vegetables.

PROBLEM FORMULATION

Flonicamid (N-cyanomethyl-4-trifluoromethylnicotin amide) is an insecticide with a “unique” mode of action (according to the Regist rant) with no known cross-resistance to organophosphates, carbamates, pyrethroids, and ne onicotinoids. The chemical structure of flonicamid and its degradation products are provided in Figures 1 and 2 . Chemical identification and physical chemical properties of flonicamid are provided in Table 1

.

Figure 1. Chemical Structure of Flonicamid

Structure of TFNG

Structure of TFNA 

### N CF 3



### N H O

N

N CF 3



### N H O

O OH



### N CF 3



### OH O

### 3 Structure of TFNA-OH

Structure of TFNA-AM

Structure of TFNG-AM

Figure 2. Chemical Structure of Flonicamid Degradation Products

Table 1. Chemical Identification Information for Flonicamid.

Chemical name Property Chemical Abstract Service number 158062-67-0 Empirical Formula C 9 H 6 F 3 N 3 O Molecular weight 229 g/mole Aqueous Solubility 5300 mg/L Vapor Pressure (25  C) 7.07X10 -9 torr



### Use Characterization

IR-4 is seeking registration of se veral new uses of flonicamid [Beleaf TM 

### -50SG Insecticide( EPA Reg No. 71512-10) and Flonicamid 50WG (EPA Reg. No. 71512-9) for the control of aphids, fleahopper, whitefly, and plant bugs. The pr oposed new use requests ground, aerial, or 

### N CF 3



### OH O

OH

N CF 3



### NH 2 

### O

N CF 3



### N H O

O NH 2

### 4 chemigation spray applications of flonicamid at a maximum seasonal application rate of 0.267 lb ai/A. Table 2 provides a summary of the proposed new uses of flonicamid.

Table 2. Proposed New Uses for Flonicamid

Crop/Site Application Type/ Method Single Application Rate Range

(lb a.i./A) Maximum Application Rate Per Season b

(lb a.i./A) Maximum Application

Number Minimum Retreatment Interval

(days) Fruiting Vegetables

Ground/Aerial /Chemigation 0.13375 0.2675 2 7 Pome Fruit Group 0.089 0.2675 3 7 Stone Fruit Group 0.089 0.2675 3 7 Tree Nuts 0.089 0.2675 3 7 Alfalfa/Clover for Seed 0.089 0.175 2 7 Mint 0.089 0.267 3 14



### The proposed new uses are segregated as follows : alfalfa and clover grown for seed and mint. ISK Biosciences is requesting th e addition of flonicamid use on tree nuts. The IR-4 is proposing expanding to the full crop group for pome fruit a nd stone fruit. Additionally, the IR-4 is requesting to increase the applicat ion rate for fruiting vegetables.

Previous Drinking Water Assessments

Table 3 provides maximum drinking water concentratio ns associated with current registrations of Flonicamid 50WG (EPA Reg. No. 71512-9) an d Beleaf 50 SG (EPA Reg. No. 71512-10).

### 5 Table 3. Maximum EDWCs from Previous Dr inking Water Assessments for Flonicamid

Crop Model Scenario Residue Peak Annual Average 30 year Annual Average Reference μg/L Tomato

P/E PA tomato Parent 5.4 0.20 0.11

D308562 Potato ME potato Apple NC apple Apple NC apple Combined Residues 8.9 1.9 0.94 Potato ME potato Tomato PA tomato SCI-GROW Parent 0.00061 SCI-GROW Combined Residues 0.00137

Low Growing Berries P/E OR Berries

Parent 7.004 0.139 0.065

D396906 ME Potato CA Strawberry
FL Strawberry

OR Berries

Combined Residues 9.031 0.968 0.488 ME Potato CA Strawberry FL Strawberry

Rapeseed P/E ND Wheat Parent 2.998 0.097 0.045 ND Canola OR Wheat ND Wheat Combined Residues 3.755 0.964 0.546 ND Canola OR Wheat
Cranberry Tier 1 Rice NA Parent 278.87 Combined Residues 285.44 SCI-GROW Parent 0.000753 SCI-GROW Combined Residues 0.00132



### Environmental Fate Assessment

Flonicamid (K oc 

### = 11.2 - 20.7) and its degradation pr oducts (TFNA, TFNG, TFNA-AM) are expected to be very mobile in terrestrial and aquatic environments. Laboratory K oc 

### values for the degradation products were not calculated from submitted batch equilibrium studies due to the lack of sorption on the test soils. Flonicamid is stable to hydrolysis and photolysis, but degrades rather quickly in aerobic environments (soil t 1⁄2 

### = 1.2 – 3.1 days; aquatic total system t 1⁄2 

### = 36 – 44 days), and more slowly under anaerobic conditions (t 1⁄2 

### = 161 days). Both parent and degradation products (TFNA, TFNG, TFNA-AM, TFNA-OH) ra pidly degrade in aerobic environments, and more slowly under anaerobic conditions.

Conceptual Model

### 6 Flonicamid applications can lead to surface wa ter contamination through spray drift, runoff, sediment erosion and ground water contamination through leaching. Flonicamid rapidly degrades in soil to form TFNA, TFNG, TFNA-AM and TFNA-OH. Although flonicamid and its degradation products are not persistent in so il, they exhibit low soil:water partitioning coefficients to promote leaching into ground water.

Analysis

The modeling was conducted for parent flonicam id alone, as well as flonicamid and its degradation products using a to tal residue approach. Tier I groundwater EDWCs were calculated using SCI-GROW (S creening C oncentration i n Gro undw ater, version 2.3, August 8, 2003 and PRZM-GW (version 1.0). Tier II surf ace water EDWCs were calculated using PRZM (P esticide R oot Z one M odel, version 3.12.3, June 2006) and EXAMS (EX posure A nalysis M odeling S ystem, version 2.98.04.06, April 2005) models in the PE5 shell. All Tier II surface water modeling was corrected fo r percent cropped area (PCA).

Various spray drift buffers, stated on the Beleaf TM 

### -50SG Insecticide( EPA Reg No. 71512-10) and Flonicamid 50WG labels, are listed in Table 4 . These buffers were considered in estimating the drift fraction in exposure modeling using information from Table 4 in Equation 1 . Adjusted spray drift fractions are shown in Table 5

. Table 4. Factors Required for Spray Drift Adjustment

Spray Drift Adjustment Factors Spray Drift Fraction
Ground Aerial
Streams 0.0282 A 0.0911
Reservoir 0.0086 B 0.0458 Spray Buffer (feet) 25 100 Area of Streams (ha) 0.6 Area of Reservoir (ha) 5.2609 A-AgDrift spray drift fraction calcula ted for 25 feet buffer assuming a stream width of 4 meters B-AgDrift spray drift fraction calculate d for 100 feet buffer assuming a reservoir width of 82 meters. Equation 1

Adjusted SDF = [(Stream SDF (aerial or ground) *0.6 ha)+(Reservoir SDF (aerial or round) *5.2609)]/5.2609



### Where : Adjusted SDF = Spray drift adjusted for spray drift buffer Stream SDF= AgDrift spray drift fractio n with buffer for stream with 4 meter width Reservoir SDF=AgDrift spray drift fraction with buffer for reservoir with XX meter width 0.6 ha = Area of Stream in Index Reservoir 5.2609 ha= Area of Index Reservoir

### 7 Table 5. Adjusted Spray Drift Fractions to Account for Spray Drift Buffers on the Beleaf TM 

### -50SG Insecticide and Flonicamid 50WG labels

. Application Method Spray Drift Buffer (feet) Default Spray Drift

Fraction Adjusted Spray Drift

Fraction Ground Spray 25 0.064 0.0118 Aerial Spray 100 0.16 0.0562

Surface Water

The scenario selection was based on the repres entative crops and geogr aphic distribution of crops in the United States ( Table 6 ). Peak and annual average drinking water concentrations using generated using PRZM-EXAMS (PCA-corrected) are shown in Tables 8 and 10 . The chemical input parameters for flonicamid and its degradation product are shown in Tables 7 and 9 . Pesticide application conditions (i.e., met hod, rate, application inte rval) were taken from Table 2

.

Table 6. Representative PRZM/EXAMS Standard Scenarios for Proposed Crops Crop Type/Groupings Major Crops in Standard Scenario Representative Standard Scenarios

Fruiting Vegetables Tomato, Pepper FL tomato, FL pepper, PA tomato Pome Fruit Group Apple, Pear PA apple, NC apple, OR apple Stone Fruit Group Cherry, Peach MI cherry, GA peach Tree Nut Pecans and Almonds GA pecan, Ca almond Alfalfa/Clover for Seed Alfalfa CA alfalfa Mint Mint OR mint



### Table 7. Input Parameters Used in PRZM-EXAMS, SCI-GROW, and PRZM-GW Modeling to Estimate Flonicamid Co ncentrations in Drinking Water

Study Type Flonicamid Data (PC Code:128016) Data Source

Molecular Weight 229 g/mole Calculated

Water Solubility 5.3 g/L Product Chemistry

Vapor Pressure 7.07X10 -9 torr Product Chemistry

Hydrolysis stable MRID 45656801

Aqueous Photolysis stable MRID 45656802

Aerobic Soil Metabolism 2.58 days ( 90 th confidence bound on the mean half-life) MRIDs 45854818
MRID 45656804

### 8 Aerobic Aquatic Metabolism 5.16 days (2X from the aerobic soil metabolism half-life) MRID 45854821

Anaerobic Aquatic Metabolism 482.1 days (3X anaerobic aquatic metabolism half-life) MRID 45854821

Mobility Ave K oc = 19.03 MRID 45656805



### Table 8. PCA 1 

### corrected Estimated Drinking Concentratio ns for Flonicamid in Surface Source Water

HED Crop Group Model Scenario Application Method 1 in 10 year 30 year Annual Average Peak Annual Average ug/L

Fruiting Vegetables FL tomato Ground Spray 9.279 0.173 0.056 Aerial Spray 9.064 0.174 0.062

PA tomato Ground Spray 2.381 0.134 0.080 Aerial Spray 2.502 0.151 0/099
FL pepper Ground Spray 5.882 0.157 0.039 Aerial Spray 5.882 0.162 0.047

Pome Fruit Group PA apples Ground Spray 4.964 0.292 0.072 Aerial Spray 6.238 0.270 0.102
NC apples Ground Spray 4.205 0.254 0.115 Aerial Spray 4.138 0.262 0.129
OR apples Ground Spray 2.308 0.172 0.062 Aerial Spray 2.415 0.189 0.082

Stone Fruit Group MI cherry Ground Spray 2.205 0.066 0.023 Aerial Spray 1.837 0.073 0.034
GA peach Ground Spray 0.768 0.020 0.007 Aerial Spray 0.888 0.029 0.015

Alfalfa/Clover for Seed CA alfalfa Ground Spray 1.202 0.075 0.039 Aerial Spray 1.153 0.077 0.043

Mint OR mint Ground Spray 0.221 0.011 0.008 Aerial Spray 0.345 0.024 0.021

Tree Nuts CA almonds Ground Spray 0.24 0.01 0.01 Aerial Spray 0.40 0.22 0.02
GA pecans Ground Spray 3.68 0.08 0.03 Aerial Spray 3.74 0.08 0.04 1-PCA=0.91

### 9 Table 9. Input Parameters Used in PRZM-EXAMS, SCIGROW, and PRZM-GW Modeling to Estimate Flonicamid Residue s (Flonicamid, TFNA, TFNG, TFNA-AM, TFNAOH) Concentrations in Drinking Water.

Study Type Total Toxic Residues

Molecular Weight 229 g/mole (parent ) Calculated

Water Solubility 5.3 g/L (parent ) Product Chemistry

Vapor Pressure 7.07 x 10 -9 torr (mm Hg, parent molecule) Product Chemistry

Hydrolysis stable (parent molecule, no data available for degradation products) MRID 45656801

Aqueous Photolysis Stable (parent molecule, no data available for degradation products) MRID 45656802

Aerobic Soil Metabolism 4.2 days\ (mean t 1/2 + (t 90 x s)/n 1/2 ) MRID 45854818 MRID 45656804

Aerobic Aquatic Metabolism 55.1 days \ (mean t 1/2 + (t 90 x s)/n 1/2 ) MRID 45854821

Anaerobic Aquatic Metabolism stable MRID 45854821

Mobility 0 mL/g K oc for degradation products because there was no measurable sorption observed in batch equilibrium studies. MRID 45656805 MRID 45854901 MRID 45854904 MRID 45854902

### 10 Table 10. PCA 1 

### corrected Estimated Drinking Concentratio ns for Flonicamid and Its Degradation Products (TFNA, TFNG, TFNA-AM, TF NA-OH) in Surface Source Water

HED Crop Group Model Scenario Application Method 1 in 10 year 30 year Annual Average Peak Annual Average ug/L

Fruiting Vegetables FL tomato Ground Spray 10.077 0.898 0.315 Aerial Spray 9.922 0.903 0.342

PA tomato Ground Spray 5.614 1.267 0.514 Aerial Spray 5.598 1.343 0.620
FL pepper Ground Spray 6.910 0.545 0.244 Aerial Spray 6.777 0.519 0.208

Pome Fruit Group PA apples Ground Spray 5.738 1.271 0.519 Aerial Spray 7.347 1.559 0.857
NC apples Ground Spray 5.393 1.389 0.704 Aerial Spray 5.476 1.454 0.794
OR apples Ground Spray 2.944 0.794 0.383 Aerial Spray 3.203 0.908 0.511

Stone Fruit Group MI cherry Ground Spray 3.112 1.029 0.341 Aerial Spray 2.522 0.975 0.450
GA peach Ground Spray 0.892 0.189 0.092 Aerial Spray 1.244 0.293 0.191

Alfalfa/Clover for Seed CA alfalfa Ground Spray 1.306 0.416 0.285 Aerial Spray 1.281 0.455 0.328

Mint OR mint Ground Spray 0.466 0.129 0.070 Aerial Spray 0.695 0.249 0.193

Tree Nuts Ca Almonds Ground Spray 0.56 0.14 0.11 Aerial Spray 0.82 0.24 0.22

GA Pecans Ground Spray 3.94 0.51 0.25 Aerial Spray 4.15 0.54 0.29 1-PCA=0.91



### Groundwater

SCI-GROW

The chemical input parameters for flonicamid and its degradation products are shown in Tables 7 and 9 . Pesticide application conditions ( i.e. , method, rate, application interval) and SCIGROW EDWCs are shown in Table 12

.

### 11 Table 12: Estimated Drinking Water Concentr ations of Flonicamid and Its Degradation Products (TFNA, TFNG, TFNA-AM, TFNA- OH) in Ground Water Using SCI-GROW Residues Application Rate lbs ai/A Application Number EDWC (ug/L)

Flonicamid 0.133 2 0.00075

Flonicamid + Degradation Products (TTR) 0.133 2 0.00131



### PRZM-GW

The chemical input parameters and applicati on conditions for flonicamid and its degradation products are shown in Tables 7

, 9, and 12 . The PRZM-GW EDWCs are shown in Table 13

. Table 13: Estimated Drinking Water Concen trations of Flonicamid and Total Toxic Residues (Flonicamid ,TF NA, TFNG, TFNA-AM, TFNA-OH) in Ground Water Using PRZM-GW

Residue Scenario Peak Concentration Average Breakthrough Concentration Breakthrough Time

μg/L Days Flonicamid FLCitrus 2.18 0.79 392 WI 4.16 1.92 1175 Flonicamid+Degradation Products FLCitrus 11.5 5.86 236 WI 15.9 9.92 868

Monitoring Data

There are no water monitoring data for flonicam id in USGS National Water-Quality Assessment Program (NAWQA), USEPA/USGS Pilot Reservoi r Monitoring Program, USDA Pesticide Data Program (PDP), and California Departme nt of Pesticide Regulation (CDPR).

### 12 

## Appendix A

PRZM/EXAMS OUTPUT (F L Tomato Scenario)

Flonicamid

stored as FLTOM.out Chemical: FLONICAMIDE PRZM environment: FLtomatoSTD_V2.txt modified Tueday, 20 May 2008 at 12:00:14 EXAMS environment: ir298.exv modified Tueday, 26 August 2008 at 06:14:08 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:22 Water segment concentrations (ppb)

Year Peak 96 hr 21 Da y 60 Day 90 Day Yearly 1961 0.43 0.3356 0.2022 0.08136 0.05427 0.01339 1962 2.445 1.91 0.9018 0.3402 0.2269 0.05598 1963 10.16 7.719 3.211 1.184 0.7894 0.1948 1964 8.164 6.161 2.54 0.9738 0.6497 0.1599 1965 0.5894 0.4416 0.2686 0.1111 0.07409 0.0183 1966 0.4106 0.3073 0.1753 0.07431 0.04957 0.01223 1967 0.4078 0.3032 0.1719 0.06517 0.04347 0.01073 1968 2.233 1.752 0.8348 0.3368 0.2247 0.05529 1969 5.35 4.239 1.934 0.7234 0.4824 0.119 1970 0.4362 0.3331 0.1888 0.109 0.07272 0.01796 1971 7.782 5.817 2.274 0.9908 0.661 0.1631 1972 11.62 8.65 3.414 1.277 0.8519 0.2096 1973 6.242 4.613 1.797 0.6759 0.4508 0.1113 1974 0.514 0.3919 0.2573 0.108 0.07203 0.01779 1975 0.4451 0.3705 0.2541 0.1033 0.06894 0.01701 1976 3.854 2.967 1.404 0.5549 0.3701 0.09108 1977 12.19 9.276 4.728 1.767 1.178 0.2908 1978 0.7577 0.6128 0.3538 0.1408 0.09393 0.02322 1979 2.803 2.122 0.8966 0.3704 0.2471 0.06096 1980 1.737 1.305 0.5825 0.2405 0.1604 0.03947 1981 0.8251 0.6121 0.4072 0.187 0.1247 0.03078 1982 2.744 2.07 0.9591 0.3723 0.2483 0.06127 1983 0.7153 0.5355 0.2867 0.1311 0.08745 0.02158 1984 0.5415 0.4057 0.2159 0.1203 0.08028 0.01976 1985 1.862 1.462 0.7552 0.315 0.2101 0.05185 1986 0.4585 0.3432 0.2408 0.09935 0.06627 0.01636 1987 4.109 3.23 1.587 0.6088 0.406 0.1002 1988 0.6017 0.4551 0.3464 0.1516 0.1012 0.0249 1989 0.4028 0.2957 0.1962 0.07758 0.05174 0.01277 1990 1.058 0.7793 0.3604 0.1426 0.09512 0.02347

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.032258064516129 12.19 9.276 4.728 1.767 1.178 0.2908 0.0645161290322581 11.62 8.65 3.414 1.277 0.8519 0.2096 0.0967741935483871 10.16 7.719 3.211 1.184 0.7894 0.1948 0.129032258064516 8.164 6.161 2.54 0.9908 0.661 0.1631

### 13 0.161290322580645 7.782 5.817 2.274 0.9738 0.6497 0.1599 0.193548387096774 6.242 4.613 1.934 0.7234 0.4824 0.119 0.225806451612903 5.35 4.239 1.797 0.6759 0.4508 0.1113 0.258064516129032 4.109 3.23 1.587 0.6088 0.406 0.1002 0.290322580645161 3.854 2.967 1.404 0.5549 0.3701 0.09108 0.32258064516129 2.803 2.122 0.9591 0.3723 0.2483 0.06127 0.354838709677419 2.744 2.07 0.9018 0.3704 0.2471 0.06096 0.387096774193548 2.445 1.91 0.8966 0.3402 0.2269 0.05598 0.419354838709677 2.233 1.752 0.8348 0.3368 0.2247 0.05529 0.451612903225806 1.862 1.462 0.7552 0.315 0.2101 0.05185 0.483870967741936 1.737 1.305 0.5825 0.2405 0.1604 0.03947 0.516129032258065 1.058 0.7793 0.4072 0.187 0.1247 0.03078 0.548387096774194 0.8251 0.6128 0.3604 0.1516 0.1012 0.0249 0.580645161290323 0.7577 0.6121 0.3538 0.1426 0.09512 0.02347 0.612903225806452 0.7153 0.5355 0.3464 0.1408 0.09393 0.02322 0.645161290322581 0.6017 0.4551 0.2867 0.1311 0.08745 0.02158 0.67741935483871 0.5894 0.4416 0.2686 0.1203 0.08028 0.01976 0.709677419354839 0.5415 0.4057 0.2573 0.1111 0.07409 0.0183 0.741935483870968 0.514 0.3919 0.2541 0.109 0.07272 0.01796 0.774193548387097 0.4585 0.3705 0.2408 0.108 0.07203 0.01779 0.806451612903226 0.4451 0.3432 0.2159 0.1033 0.06894 0.01701 0.838709677419355 0.4362 0.3356 0.2022 0.09935 0.06627 0.01636 0.870967741935484 0.43 0.3331 0.1962 0.08136 0.05427 0.01339 0.903225806451613 0.4106 0.3073 0.1888 0.07758 0.05174 0.01277 0.935483870967742 0.4078 0.3032 0.1753 0.07431 0.04957 0.01223 0.967741935483871 0.4028 0.2957 0.1719 0.06517 0.04347 0.01073

0.1 9.9604 7.5632 3.1439 1.16468 0.77656 0.19163 Average of yearly averages: 0.0681616666666667

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLTOM Metfile: w12844.dvf PRZM scenario: FLtomatoSTD_V2.txt EXAMS environment file: ir298.exv Chemical Name: FLONICAMIDE Description Variable Name Value Units Comments Molecular weight mwt 229 g/mol Henry's Law Const. henry atm-m^3/mol Vapor Pressure vapr 7.07E-9 torr Solubility sol 5300 mg/L Kd Kd mg/L Koc Koc 19.03 mg/L Photolysis half-life kdp days Half-life Aerobic Aquatic Metabolism kbacw 5.16 days Halfife Anaerobic Aquatic Metabolism kbacs 482.1 days Halfife Aerobic Soil Metabolism as m 2.58 days Halfife Hydrolysis: pH 7 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.1498 kg/ha

### 14 Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.056 fraction of application rate applied to pond Application Date Date 1-5 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate 0.1498 kg/ha Record 17: FILTRA IPSCND 1 UPTKF Record 18: PLVKRT PLDKRT FEXTRC 0.5 Flag for Index Res. Run IR Reservoir Flag for runoff calc. RUNOFF total none, monthly or total(average of entire run)



## Total Toxic Residues

stored as FLTOM.out Chemical: FLONICAMIDE PRZM environment: FLtomatoSTD_V2.txt modified Tueday, 20 May 2008 at 12:00:14 EXAMS environment: ir298.exv modified Tueday, 26 August 2008 at 06:14:08 Metfile: w12844.dvf modified Tueday, 26 August 2008 at 06:14:22 Water segment concentrations (ppb)

Year Peak 96 hr 21 Da y 60 Day 90 Day Yearly 1961 0.591 0.5718 0.5002 0.3727 0.2844 0.07521 1962 3.192 3.054 2.529 1.586 1.174 0.3078 1963 11 10.52 8.458 5.225 3.839 0.9996 1964 9.299 8.749 7.123 4.39 3.229 0.8529 1965 0.9105 0.856 0.6784 0.4617 0.3526 0.09466 1966 0.6741 0.6408 0.506 0.3974 0.3087 0.08273 1967 0.5516 0.5181 0.403 0.2791 0.2112 0.05595 1968 3.01 2.882 2.369 1.509 1.138 0.3015 1969 6.108 5.764 5.077 3.237 2.391 0.6261 1970 1.815 1.741 1.366 0.8518 0.6694 0.183 1971 10.03 9.594 7.475 4.549 3.465 0.9235 1972 13.39 12.58 9.847 5.968 4.37 1.142 1973 6.742 6.33 4.926 3.011 2.214 0.5841 1974 0.8879 0.8341 0.6628 0.4548 0.347 0.09259 1975 0.8048 0.7629 0.6715 0.4542 0.346 0.09195 1976 4.535 4.383 3.502 2.214 1.676 0.4424 1977 15.66 14.73 12.62 8.109 5.995 1.568 1978 1.207 1.133 1.008 0.6838 0.5155 0.1377 1979 3.498 3.296 2.646 1.618 1.211 0.3232 1980 1.962 1.853 1.619 1.132 0.8504 0.2256 1981 2.097 1.969 1.617 1.086 0.8287 0.2218 1982 2.905 2.733 2.402 1.636 1.218 0.32 1983 1.116 1.049 0.8354 0.5606 0.432 0.115 1984 1.904 1.794 1.417 0.886 0.695 0.1893 1985 2.755 2.589 2.146 1.621 1.222 0.3251 1986 0.7933 0.7457 0.603 0.4137 0.3144 0.08351 1987 5.904 5.604 4.545 2.866 2.12 0.5569

### 15 1988 1.457 1.371 1.076 0.7373 0.5673 0.151 1989 0.5919 0.5553 0.4817 0.3258 0.245 0.06455 1990 1.331 1.249 1.004 0.6486 0.4926 0.1301

Sorted results Prob. Peak 96 hr 21 Day 60 Day 90 Day Yearly 0.032258064516129 15.66 14.73 12.62 8.109 5.995 1.568 0.0645161290322581 13.39 12.58 9.847 5.968 4.37 1.142 0.0967741935483871 11 10.52 8.458 5.225 3.839 0.9996 0.129032258064516 10.03 9.594 7.475 4.549 3.465 0.9235 0.161290322580645 9.299 8.749 7.123 4.39 3.229 0.8529 0.193548387096774 6.742 6.33 5.077 3.237 2.391 0.6261 0.225806451612903 6.108 5.764 4.926 3.011 2.214 0.5841 0.258064516129032 5.904 5.604 4.545 2.866 2.12 0.5569 0.290322580645161 4.535 4.383 3.502 2.214 1.676 0.4424 0.32258064516129 3.498 3.296 2.646 1.636 1.222 0.3251 0.354838709677419 3.192 3.054 2.529 1.621 1.218 0.3232 0.387096774193548 3.01 2.882 2.402 1.618 1.211 0.32 0.419354838709677 2.905 2.733 2.369 1.586 1.174 0.3078 0.451612903225806 2.755 2.589 2.146 1.509 1.138 0.3015 0.483870967741936 2.097 1.969 1.619 1.132 0.8504 0.2256 0.516129032258065 1.962 1.853 1.617 1.086 0.8287 0.2218 0.548387096774194 1.904 1.794 1.417 0.886 0.695 0.1893 0.580645161290323 1.815 1.741 1.366 0.8518 0.6694 0.183 0.612903225806452 1.457 1.371 1.076 0.7373 0.5673 0.151 0.645161290322581 1.331 1.249 1.008 0.6838 0.5155 0.1377 0.67741935483871 1.207 1.133 1.004 0.6486 0.4926 0.1301 0.709677419354839 1.116 1.049 0.8354 0.5606 0.432 0.115 0.741935483870968 0.9105 0.856 0.6784 0.4617 0.3526 0.09466 0.774193548387097 0.8879 0.8341 0.6715 0.4548 0.347 0.09259 0.806451612903226 0.8048 0.7629 0.6628 0.4542 0.346 0.09195 0.838709677419355 0.7933 0.7457 0.603 0.4137 0.3144 0.08351 0.870967741935484 0.6741 0.6408 0.506 0.3974 0.3087 0.08273 0.903225806451613 0.5919 0.5718 0.5002 0.3727 0.2844 0.07521 0.935483870967742 0.591 0.5553 0.4817 0.3258 0.245 0.06455 0.967741935483871 0.5516 0.5181 0.403 0.2791 0.2112 0.05595

0.1 10.903 10.4274 8.3597 5.1574 3.8016 0.99199 Average of yearly averages: 0.375591666666667

Inputs generated by pe5.pl - Novemeber 2006

Data used for this run: Output File: FLTOM Metfile: w12844.dvf PRZM scenario: FLtomatoSTD_V2.txt EXAMS environment file: ir298.exv Chemical Name: FLONICAMIDE Description Variable Name Value Units Comments Molecular weight mwt 229 g/mol Henry's Law Const. henry atm-m^3/mol Vapor Pressure vapr 7.07E-9 torr Solubility sol 5300 mg/L

### 16 Kd Kd mg/L Koc Koc 0 mg/L Photolysis half-life kdp days Half-life Aerobic Aquatic Metabolism kbacw 55.1 days Halfife Anaerobic Aquatic Metabolism kbacs days Halfife Aerobic Soil Metabolism as m 4.28 days Halfife Hydrolysis: pH 7 days Half-life Method: CAM 2 integer See PRZM manual Incorporation Depth: DEPI cm Application Rate: TAPP 0.1498 kg/ha Application Efficiency: APPEFF 0.95 fraction Spray Drift DRFT 0.056 fraction of application rate applied to pond Application Date Date 1-5 dd/mm or dd/mmm or dd-mm or dd-mmm Interval 1 interval 7 days Set to 0 or delete line for single app. app. rate 1 apprate 0.1498 kg/ha Record 17: FILTRA IPSCND 1 UPTKF Record 18: PLVKRT PLDKRT FEXTRC 0.5 Flag for Index Res. Run IR Reservoir Flag for runoff calc. RUNOFF total none, monthly or total(average of entire run)



## SCI-GROW OUTPUT

Flonicamid

SCIGROW VERSION 2.3 ENVIRONMENTAL FATE AND EFFECTS DIVISION OFFICE OF PESTICIDE PROGRAMS U.S. ENVIRONMENTAL PROTECTION AGENCY SCREENING MODEL FOR AQUATIC PESTICIDE EXPOSURE

SciGrow version 2.3 chemical:Flomicamid time is 5/23/2013 14:40:56

------------------------------------------------------------------------ Application Number of Total Use Koc Soil Aerobic rate (lb/acre) applications (l b/acre/yr) (ml/g) metabolism (days)

------------------------------------------------------------------------ 0.133 2.0 0.266 1.90E+01 2.6

------------------------------------------------------------------------

### 17 groundwater screening cond (ppb) = 7.50E-04 ************************************************************************



## Total Toxic Residues

SCIGROW VERSION 2.3 ENVIRONMENTAL FATE AND EFFECTS DIVISION OFFICE OF PESTICIDE PROGRAMS U.S. ENVIRONMENTAL PROTECTION AGENCY SCREENING MODEL FOR AQUATIC PESTICIDE EXPOSURE

SciGrow version 2.3 chemical:Flonicamid time is 5/23/2013 14:39:41

------------------------------------------------------------------------ Application Number of Total Use Koc Soil Aerobic rate (lb/acre) applications (l b/acre/yr) (ml/g) metabolism (days)

------------------------------------------------------------------------ 0.133 2.0 0.266 0.00E+00 4.2

------------------------------------------------------------------------ groundwater screening cond (ppb) = 1.31E-03 ************************************************************************

### 18 

## PRZM-GW OUTPUT

Flonicamid

### 19 

## Total Toxic Residues