# Support Documents for Significant New Use Rule (SNUR) on
Premanufacture Notice (PMN)

P-08-704

EPA Docket EPA-HQ-OPPT-2010-1075

# Index

A-001 Structure Activity Team (SAT) Report for PMN P -08-704

A-002 Initial Review Engineering Report for PMN P -08-704

A-003 Initial Review Exposure Report for PMN P -08-704

# A-001 Structure Activity Team (SAT) Report

for PMN P-08-704

## SAT Report PMN Number: P-08-0704 SAT Date: 9/19/2008

Related cases : Health related cases: Ecotox related cases:

Concern levels : 

### Type of Concern: Health Eco Comments Level of Concern: 2-3 3

Persistence Bioaccum Toxicity Comments 1 1 2
Exposure Based Review : Health: Yes Ecotox: Yes

Routes of exposure : Health: Inhalation, dermal, and drinking water. Ecotox: All releases to water Fate: ;
Keywords : Keywords: MUTA, ONCO, DEVEL, REPRO< IRR, SENS-DERMAL/RESPIRATORY, AQUATOX-A,C
Summary of Assessment :

Fate : Fate Summary: P-08-0704 FATE: Liquid with MP < 25 EC (E) log Kow = 2.83 (E); S = 483 mg/L at 25 EC (E) VP = 2 torr at 25 EC ( N OMO5) BP = 171 EC (M) H = 6.58E-4 (E) log Koc = 1.72 (E) log Fish BCF = 1.48 (E) POTW removal (%) = 0-25 via stripping and biodeg Time for complete ultimate aerobic biodeg = wk-mo Sorption to soils/sediments = moderate

### Volatilization half-life from a standard river = 2 hrs Volatilization half-life from a standard lake = 5 da Atmospheric Oxidation Half-life = 17 hr via OH radical PBT Potential: P1B1 *CEB FATE: Migration to ground water = moderate

Health : Health Summary: Absorption is moderate with reaction of all routes based on analogs. There is concern for mutagenicity, oncogenicity, developmental toxicity, reproductive toxicity, irritation, and dermal and respiratory sensitization for A mixture of is reported to be a dermal sensitizer in guinea pigs . A mixture of is reported to be a severe skin irritant and a mild eye irritant . Moderate high concern.

Ecotox :

Test Organism Test Type Test End Point Predicted Measured Comments

fish 96-h LC50 4.8 daphnid 48-h LC50 9.1 green algal 96-h EC50 8.3 fish

_ chronic value 0.005 daphnid chronic value 0.85 algal

_ chronic value 7.7 Sewage Sludge 3-h EC50

_ Sewage Sludge

_ Chronic Value

_ Ecotox Values Comments: Predictions are based on SARs for SAR chemical class = ; log Kow = 2.83 (EPI); p H7; effective concentrations based on 100% active ingredients and mean measured concentrations of ; DW hardness < 150.0 mg/L as CaCO3; and DW TOC <2.0 mg/L;

Factors Values Comments Assessment Factor 10 Concentration of Concern ( p pb) 1

SARs SAR Class

Ecotox Factors Comments:

SAT Chair: Becky Jones

# A-002 Initial Review Engineering Report

for PMN P-08-704

### INITIAL REVIEW ENGINEERING REPORT P-08-0704 Focus Ready Draft 9/25/2008

ENGINEER: Jon \ DGR PV (kg/yr):

Revision Notes/Assessment Overview:

SUBMITTER:

USE:

OTHER USES:

MSDS: LABEL : N o
Gen Eqpt: Respirator: Health Effects: TLV/PEL : -

CRSS : Chemical Name: S-H2O: VP: MW: %<500 %<1000 Physical State and Misc CRSS Info: Neat: Mfg:

Consumer Use : N o
SAT (concerns):

Migration to groundwater: Moderate PBT rating: P 1 B 1 T 2 Health: 2-3, Dermal, Drinking Water, Inhalation, Eco: 3, Water (All releases to water with a CC = 1 ppb),

OCCUPATIONAL EXPOSURE RATING: 2-3B

NOTES & KEY ASSUMPTIONS:POLLUTION PREVENTION CONSIDERATIONS: P2 Claim:

P2 REC:

EXPOSURE-BASED REVIEW:P-08-0704P-08-0704P-08-0704

# A-003 Initial Review Exposure Report

for PMN P -08-704Page of 9/24/2008

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Chemical ID: P080704 Reviewer: Flessner

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10 CC=1 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ; exposure calculation(s) 3 mg/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day
1.45 --- 0.30 --- --- --- --- --- --- 2.94e-02 ---

--- 3.80e-04 --- 4.88e-05 --- --- 7.89e-05 --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.
2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.
3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Remarks:

Exposure Based Criteria

Parameter Drinking (Surface) Water Do se (mg/kg/day) Fish Ingestion Dose (mg/kg/day) Inhalation Dose (mg/kg/day) Groundwater Dose (mg/kg/day) Surface Water Release After Treat ment (kg/yr) Total Release After Treatment (kg/yr)

Fate test recommendations?:Page of 9/24/2008

INITIAL REVIEW EXPOSU RE REPORT (IRExR)

Summary Table: Endpoints assessed

Endpoints-Assessed Table Reasons for not assessing releases

Endpoints/Assessment Cycles 1 Releases Assessed in NCEM2? No XB Testing Required No Hazard Concern No Releases Release Below Acute Threshold 5 Release Below Chronic Threshold 5 Other

Ingestion Surface water Ground water (landfill) Consumer Use: DtD 2 Inhalation Air: incineration (stack) Air: fugitive Consumer Use: CEM 3 Dermal Consumer Use: CEM Eco Surface water: ADR conc and/or PDM 4 Consumer Use: DtD

1 Assessment cycles are endpoint concentrations and dose calculations within the NCEM2 model.
2 Down-the-Drain Module
3 Consumer Exposure Module
4 Probabilistic Dilution Model
5 The threshold values for assessing endpoints are 1 mg/day for acute doses and 1 mg/year for chronic doses.

Remarks:Page of 9/24/2008

INITIAL REVIEW EX POSURE REPORT

Chemical ID: P080704 Assessor: Flessner

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites Release Activity: Max ADR
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases:
(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge
Release Days/yr:

Per Site Release:
(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks: All releases are from PDM not run because release days are less than 20.Page of 9/24/2008

INITIAL EXPOSURE REVIEW REPORT

Chemical ID: P080704 SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO NUMBER:1 RELEASE ACTIVITY:

FACILITY NAME:

FACILITY LOCATION:

RECEIVING WATER NAME:

REACH NUMBER: FACILITY ON REACH DISCHARGE TYPE:

NPDES PERMIT # EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT
FLOW (MLD)
CONCENTRATION ( μ g/L) 5621.88 1.73E+04 2.92E+04 2.92E+04 NA

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion Units

Cancer

LADD pot 1.20E-04 mg/kg/day 1.54E-05 mg/kg/day

LADC pot 6.16E-03 mg/L 0.18 mg/kg

Acute

ADR pot 1.45 mg/kg/day 0.30 mg/kg/day

Surface Water Comments:Page of 9/24/2008

INITIAL EXPOSURE REVIEW REPORT Chemical ID: P080704

INHALATION EXPOSURE ESTIMATES (POST-TREATMENT)

SCENARIO #: 1 RELEASE ACTIVI TY

RELEASE DESCRIPTION:

METHOD OF CALCULATION: Screen3

EXPOSED POPULATION: Adult

Number of Sites:
Per Site Fugitive Release: kg/site/day
Fugitive Release Days per Year: days
% Removal via Fugitive Release: %
Total Fugitive Release: kg/yr
Max Annual Average Air Concentration (Fugitive): 3.58E-02 μg/m 3

Max 24 Hour Average Air Concentration(Fugitive): 160.00 μg/m 3

Per Site Stack Release: kg/site/day
Stack Release Days per Year: days

% Removal via Stack Release: %

Total Stack Release: kg/yr
Max Annual Average Air Concen tration (Stack): 6.27E-04 μg/m 3

Max 24 Hour Average Air Concentration (Stack): 1.15 μg/m 3

ASSUMPTIONS
Exposure Units Results (Stack) Results (Fugitive) ED (years) AT (years) BW (kg) Inh. Rate (m 3 /hr)

Cancer

LADD pot (mg/kg/day) N/A 2.63E-06 30.00 75.00 71.80 0.55

LADC pot (mg/m 3 ) N/A 1.43E-05 30.00 75.00 NA NA

Acute

ADR pot

(mg/kg/day) N/A 2.94E-02 NA 1 day 71.80 0.55

Inhalation Comments:Page of 9/24/2008

Stack Parameter Data Fugitive Parameter Data Stack Height 10.00 m Release Height: 3.00 m

Inside Stack Diameter: 0.10 m Length of Release Opening: 10.00 m

Stack Gas Exit Velocity: 0.10 m/sec Width of Release Opening: 10.00 m

Stack Gas Temperature: 293.00 K

Meteorological and Terrain Information:

Surrounding Land Use: Rural
Terrain Height: 0.00 m

Distance to Residence of Interest: 100.00 m
Meteorological Class: Full
Stability Class: NA
Wind Speed: NA

Downwash Information:

Facility Length: NA m
Facility Width: NA m
Facility Height: NA mPage of 9/24/2008

INITIAL REVIEW EXPOSURE REPORT

Chemical ID: P080704 Assessor:

ENVIRONMENTAL RELEASES

Scenario#:2 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases:
(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge
Release Days/yr:

Per Site Release:
(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks:Page of 9/24/2008

INITIAL EXPOSURE REVIEW REPORT

Chemical ID: P080704 SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO NUMBER:2 RELEASE ACTIVITY:

FACILITY NAME:

FACILITY LOCATION:

RECEIVING WATER NAME

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE:

NPDES PERMIT #: EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT
FLOW (MLD)
CONCENTRATION ( μ g/L)

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion Units

Cancer

LADD pot 3.80E-04 mg/kg/day 4.88E-05 mg/kg/day

LADC pot 1.95E-02 mg/L 0.58 mg/kg

Surface Water Comments:Page of 9/24/2008

INITIAL EXPOSURE REVIEW REPORT Chemical ID: P080704

DRINKING WATER EXPOSURE ESTIMATES FROM LANDFILL RELEASES

SCENARIO #: 2 ACTIVITY:

RELEASE DESCRIPTION:

EXPOSED POPULATION: Adult

NUMBER OF SITES NON-SLUDGE LANDFILL RELEASE AND DAYS OF RELEASE (kg/site/day)/(days) LANDFILLED SLUDGE 1
AND DAYS OF RELEASE (kg/site/day)/(days) MIGRATION DESCRIPTOR 2 ADSORPTION TO WASTEWATER SLUDGE (%) DRINKING WATER TREATMENT (%)

1 Landfilled sludge equals the fraction adsorbed to wastewater treatment sludge times the surface water pre-treatment release.

2 Migration Descriptor Log Koc Groundwater Concentration (GWC) (mg/L per kg release) Negligible no migration None Negligible to slow > 4.5 3.21E-6 Slow <4.5 to 3.5 2.67E-5 Moderate <3.5 to 2.5 5.95E-5 Rapid <2.5 7.55E-5

ASSUMPTIONS Exposure Units Results ED (years) AT (years) BW (kg) IR (L/day)
Cancer
LADD pot (mg/kg/day) 7.89E-05 30.00 75.00 71.80 1.40
LADC pot (mg/L) 4.05E-03 30.00 75.00 NA NA

REMARKS:Page of 9/24/2008



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedence of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure ≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water ≥ 10,000 kg/yr release to environment (post-treatment) ≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences: ≥ 2,000 kg/yr release to environment (post-treatment) ≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.2/19/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P080704 Reviewer: Delpire

Updated based on revised engineering report,

Results Table: Dose, Concentration, and Days Exceeded Results Summary

Exposure Scenario 1 Water Landfill Stack Air Fugitive Air Drinking Water Fish Ingestion

ADR LADD ADR LADD 7Q10 CC=1 PDM Days Exceeded LADD ADR LADD ADR LADD Release activity(ies) 2 ; exposure calculation(s) 3 mg/kg/day mg/kg/day mg/kg/day mg/kg/day μ g/l # Days mg/kg/day mg/kg/day mg/kg/day mg/kg/day mg/kg/day
3.91E-03 --- 8.19E-04 --- 78.86

--- --- --- --- 2.94E-02 ---

--- 1.62E-06 --- 2.09E-07 --- --- --- --- --- --- ---

1 Exposure scenario titles consist of release activ ity followed by exposure calculation abbreviation.
2 Release activities are from engineering report's Manufactur ing (Mfg), Processing (Proc) and Use release activity labels. Multiple release activities are combined in one exposure scenario if their releases occur at same location.
3 Exposure calculations are Acute Dose Rate (ADR), Lifetime Average Daily Dose (LADD), and Probabilistic Dilution Model (PDM). There may be one, two, or all three exposure calculations per exposure scenario. CC is the aquatic concentration of concern.

Remarks:

Fate testing recommendations?: (default is NA)

Exposure Based Criteria

Parameter Drinking (Surface) Wa ter Dose (mg/kg/day) Fish Ingestion Dose (mg/kg/day) Inhalation Dose (mg/kg/day) Groundwater Dose (mg/kg/day) Surface Water Release After Treatment (kg/yr) Total Release After Treatment (kg/yr)2/19/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P080704 Assessor: Delpire

ENVIRONMENTAL RELEASES

Scenario#:1 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases:
(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge
Release Days/yr:

Per Site Release:
(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks: All releases are from PDM not run because release days are less than 20.2/19/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P080704 SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO NUMBER:1 RELEASE ACTIVITY:

FACILITY NAME:

FACILITY LOCATION:

RECEIVING WATER NAME:

REACH NUMBER: FACILITY ON REACH: DISCHARGE TYPE:

NPDES PERMIT #: EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT
FLOW (MLD)
CONCENTRATION ( μ g/L) 15.19 46.80 78.86 78.86 NA

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion Units

Cancer

LADD pot 1.62E-06 mg/kg/day 2.09E-07 mg/kg/day

LADC pot 8.33E-05 mg/L 2.50E-03 mg/kg

Acute

ADR pot 3.91E-03 mg/kg/day 8.19E-04 mg/kg/day

Surface Water Comments:2/19/2009

POST-FOCUS EXPOSURE REPORT Chemical ID: P080704

INHALATION EXPOSURE ESTIMATES (POST-TREATMENT)

SCENARIO #: 1 RELEASE ACTIVI TY

RELEASE DESCRIPTION:

METHOD OF CALCULATION: Screen3

EXPOSED POPULATION: Adult

Number of Sites:
Per Site Fugitive Release: kg/site/day
Fugitive Release Days per Year: days
% Removal via Fugitive Release: %
Total Fugitive Release: kg/yr
Max Annual Average Air Concentration (Fugitive): 3.58E-02 μg/m 3

Max 24 Hour Average Air Concentration(Fugitive): 160.00 μg/m 3

Per Site Stack Release: 0.00 kg/site/day
Stack Release Days per Year: 0.00 days

% Removal via Stack Release: 99.90 %

Total Stack Release: 0.00 kg/yr
Max Annual Average Air Con centration (Stack): NA μg/m 3

Max 24 Hour Average Air Concentration (Stack): NA μg/m 3

ASSUMPTIONS
Exposure Units Results (Stack) Results (Fugitive) ED (years) AT (years) BW (kg) Inh. Rate (m 3 /hr)

Cancer

LADD pot (mg/kg/day) N/A 2.63E-06 30.00 75.00 71.80 0.55

LADC pot (mg/m 3 ) N/A 1.43E-05 30.00 75.00 NA NA

Acute

ADR pot

(mg/kg/day) N/A 2.94E-02 NA 1 day 71.80 0.55

Inhalation Comments:2/19/2009

Stack Parameter Data Fugitive Parameter Data Stack Height 10.00 m Release Height: 3.00 m

Inside Stack Diameter: 0.10 m Length of Release Opening: 10.00 m

Stack Gas Exit Velocity: 0.10 m/sec Width of Release Opening: 10.00 m

Stack Gas Temperature: 293.00 K

Meteorological and Terrain Information:

Surrounding Land Use: Rural
Terrain Height: 0.00 m

Distance to Residence of Interest: 100.00 m
Meteorological Class: Full
Stability Class: NA
Wind Speed: NA

Downwash Information:

Facility Length: NA m
Facility Width: NA m
Facility Height: NA m2/19/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P080704 Assessor:

ENVIRONMENTAL RELEASES

Scenario#:2 Number of Release Sites: Release Activity:
Release Description: WATER LANDFILL Non-sludge/Sludge STACK FUGITIVE

Total Releases:
(kg/yr) (kg/yr) (kg/yr) (kg/yr)

Non-sludge/Sludge
Release Days/yr:

Per Site Release:
(kg/site/day) (kg/site/day) (kg/site/day) (kg/site/day)

Remarks: All releases are from2/19/2009

POST-FOCUS EXPOSURE REPORT

Chemical ID: P080704 SITE-SPECIFIC HUMAN AND AQUATIC EXPOSURES TO SURFACE WATER RELEASES

SCENARIO NUMBER:2 RELEASE ACTIVITY:

FACILITY NAME:

FACILITY LOCATION:

RECEIVING WATER NAME:

REACH NUMBER FACILITY ON REACH: DISCHARGE TYPE:

NPDES PERMIT #: EXPOSED POPULATION: Adult

WWT REMOVAL (%) RELEASE DAYS PRETREATMENT RELEASE (kg/site/day) POSTTREATMENT RELEASE (kg/site/day) DWT (%) BCF (L/kg)

AQUATIC EXPOSURE ESTIMATES - SURFACE WATER

FLOW DESCRIPTOR Harmonic Mean 30Q5 7Q10 1Q10 PLANT
FLOW (MLD)
CONCENTRATION ( μ g/L)

DRINKING WATER INGESTION AND FISH INGESTION EXPOSURE ESTIMATES

Exposure Units Drinking Water Results Drinking Water Units Fish Ingestion Results Fish Ingestion Units

Cancer

LADD pot 1.62E-06 mg/kg/day 2.09E-07 mg/kg/day

LADC pot 8.33E-05 mg/L 2.50E-03 mg/kg

Surface Water Comments:2/19/2009



## LEGEND FOR NEW CHEMICAL S EXPOSURE REPORT

This new chemicals exposure report wa s prepared by the Exposure Assessment Branch (EAB) of the Economics, Exposure and Technology Division, Office of Pollution Prevention and Toxics, USEPA.

The goals of these reports are to calcula te conservative (protective) estimates of exposure endpoints for consumers, the general population, and the environment.

For each exposure scenario to industrial releases, the following three endpoints are calculated: (1) maximum possible acute concentrations and doses (2) maximum possible chronic concentrations and doses (3) for water releases ≥ 20 days, the probability of exceedance of the aquatic concentration of concern These endpoints are identified by abbreviati ons on the Release Activity line, e.g., (1) max ADR , (2) max LADD , (3) max PDM . Depending on the release inputs, these e ndpoints may be calculated and presented on the same page or different pages. That is, a release activity ID of mfg; max ADR, max PDM, max LADD indicates that all the exposure endpoints were cal culated from common manufacturing release values; conversely, a release activity ID of mfg &proc; max ADR indicates that only the maximum acute exposure values were calculated for manufacturing and proce ssing releases that occurred at the same site.

For each consumer product use exposure scenario, whether exposure is to the user directly or to the general population/environment, the maximum exposure values are calculated and presented together.

In addition to the exposure values above, EPA policy dir ects that exposure and release values be compared to criteria threshold values for Exposure-based and PBT Exposure-based cases.

Exposure-based (YX) cases (those with ≥ 100,000 kg/yr production volume) Criteria are exceeded under the following conditions: Presence in consumer product with likely exposure ≥ 3E-3 mg/kg/d exposure via air, fish ingestion or drinking water ≥ 10,000 kg/yr release to environment (post-treatment) ≥ 1,000 kg/yr release to water (post-treatment)

Persistent, Bioaccumulative, Toxic (PBT) chemical s of P2B2 rating or hi gher and production volume ≥ 20,000 kg/yr Criteria are exceeded as for YX cases, with the following differences: ≥ 2,000 kg/yr release to environment (post-treatment) ≥ 200 kg/yr release to water (post-treatment)

Bolding rules in the Report: Values for endpoints above th at are also health or eco concerns are bolded.