**Exhibit    10.22**
**EXECUTIVE      EMPLOYMENT AGREEMENT**

**THIS      AGREEMENT**
**PROVECTUS      PHARMACEUTICALS, INC., **
**H.**
**Craig      Dees, Ph.D.**

**WITNESSETH:**

**WHEREAS**

**WHEREAS**

**WHEREAS**

**NOW,      THEREFORE**

| 1.   | Employment.                The Company agrees to employ the Executive, and the Executive agrees                to be                employed by the Company, on the terms and conditions set forth                herein. |
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| 2.   | Term                of Employment.                The employment of the Executive by the Company as provided under                Section 1                shall commence on January 4, 2005, and end on January 4, 2006 unless                further extended or sooner terminated as hereinafter provided. On                January                4, 2006 and on January 4th                of                each year thereafter, the term of the Executive’s employment hereunder                shall be extended automatically one (1) additional year, unless prior                to                the date of such automatic extension the Company shall have delivered                to                the Executive or the Executive shall have delivered to the Company                written                notice that the term of the Executive’s employment hereunder shall not be                extended. |
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| 3.   | Position                and Duties.                The Executive shall serve as CEO of the Company with responsibilities                and                authority as may from time to time be assigned by the Chief Executive                Officer and/or the Board of Directors of the Company. Executive agrees                to                perform faithfully and industriously the duties which the Company                may                assign to him. |
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| 4.   | Place                of Performance.                In connection with the Executive’s employment hereunder, the Executive                shall be based at the Company’s principal offices located in Knoxville,                Tennessee. |
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| 5.   | Compensation                and Benefits.                In consideration of the Executive’s performance of his duties hereunder,                the Company shall provide the Executive with the following compensation                and benefits during the term of his employment                hereunder. |
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| (a)   | Base                Salary.                The Company shall pay to the Executive an aggregate base salary at                a rate                of Two Hundred Thousand Dollars ($200,000) per annum, payable in                accordance with the Company’s normal payroll practices. Such base salary                may be increased from time to time by the Board of Directors in accordance                with the normal business practices of the                Company. |
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| (b)   | Incentive                Compensation.                The Executive shall have the right to participate in any incentive                compensation plan or bonus plan adopted by the Company without diminution                of any compensation or benefit provided for in this                Agreement. |
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| (c)   | Expenses.                The Company, as applicable, shall promptly reimburse the Executive                for all                reasonable out-of-pocket expenses incurred by the Executive in his                performance of services hereunder, including all such expenses of                travel                and living expense while away from home on business of the Company,                provided that such expenses are incurred, accounted for and documented                in                accordance with the Company’s regular policies and in compliance with IRS                Guidelines. |
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| (d)   | Employee                Benefits.                The Executive shall be entitled to continue to participate in all                Company                employee benefit plans and arrangements for which he is eligible                in effect                on the date hereof in which the Executive participates (including,                but not                limited to, any employee benefit pension plan, stock option plan,                life                insurance plan, vacation plan, disability plan, and the group                health-and-accident and medical insurance plans) as such plans may                continue or be altered by the Company Board of Directors from time                to time                at the Board’s discretion. |
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| (e)   | Vacation.                The Executive shall be entitled to reasonable and customary vacation                in                each calendar year during the term of this Agreement, in accordance                with                the Company's present policies. |
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| (f)   | Services.                The Company shall furnish the Executive with office space, secretarial                and                administrative assistance, and such other facilities and services                as shall                be suitable to his position and adequate for the performance of his                duties                hereunder. |
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| 6.   | Termination:                This Agreement shall terminate upon the first to occur of the                following: |
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| (a)   | The                death of Executive; |
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| (b)   | The                permanent disability of Executive, as defined in Paragraph                7(a)(vi); |
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| (c)   | Termination                by Company "for cause" as defined in                Paragraph 7(a)(i); |
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| (d)   | Termination                by Company "without cause" or pursuant to a "Change in Control" as                defined                in Paragraph 7(a)(ii). The Company reserves the right to terminate                the                Executive at any time, subject to the Company's obligation to pay                the                Executive Compensation as otherwise provided for herein;                or |
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| (e)   | Termination                by Executive, provided that Executive shall give not less than                thirty (30) days' written notice of termination. |
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| 7.   | Compensation                and Benefits in the Event of Termination or Acquisition of the                Company.                In the event of the termination of the Executive’s employment by the                Company during the term of this Agreement, compensation and benefits                shall                be paid as set forth below. |
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| (a)   | Definitions.                For purposes of this Agreement, the following terms shall have the                meanings indicated: |
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| (i)   | As                used in Paragraph 6(c), termination "for cause" shall include, but                shall                not be limited to, termination for Executive's use of illegal                non-prescription drugs or drug or alcohol addiction; conviction of                a                felony; intentional breach of this Agreement by Executive; or willful                negligence in carrying out the activities for which employed. "For                cause"                is not intended to include disagreements over management philosophy                or                other such intangibles. |
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| (ii)   | “Change                in Control” shall mean either: |
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| (A)   | A                sale or other disposition of substantially all of the assets of Company                or                a sale or disposition of a majority of the issued and outstanding                common                stock of Company in a single transaction or in a series of transactions                to                a single person or entity or group of affiliated persons or entities                who                were not directors or shareholders of the Company prior to such                transaction; or |
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| (B)   | A                merger of consolidation of the Company with or into any other entity,                if                immediately after giving effect to such transaction more than fifty                percent (50%) of the issued and outstanding common stock of the                surviving entity of such transaction is held by a single person or                entity                or group of affiliated persons or entities who were not directors                or                shareholders of the Company prior to such                transaction. |
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| (C)   | for                purposes of this sub-paragraph (ii), the definition of “person” shall be                as defined in Section 13(d) and 14(d) of the Securities Exchange                Act of                1934. |
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| (iii)   | “Compensation”                shall mean the base salary provided for in Paragraph 5(a)                hereof. |
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| (iv)   | “Coincident                with” shall mean any time within nine months prior to the occurrence of                a                Change in Control of the Company. |
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| (v)   | “Date                of Termination” shall mean (A) if the Executive’s employment is terminated                by reason of his death, his date of death; (B) if the Executive’s                employment is terminated for Disability, thirty (30) days after Notice                of                Termination is given (provided that the Executive shall not have                returned                to the performance of his duties as provided under sub-paragraph                (vi) of                this paragraph (a)); or (C) if the Executive’s employment is terminated by                action of either party for any other reason, the date specified in                the                Notice of Termination. |
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| (vi)   | “Disability”                shall mean the Executive’s failure to satisfactorily perform his regular                duties on behalf of the Company on a full-time basis for ninety (90)                consecutive days or such lesser period of time as provided under                the                disability insurance policy provided through Company, by reason of                the                Executive’s incapacity due to physical or mental illness, except where                within thirty (30) days after Notice of Termination is given following                such absence, the Executive shall have returned to the satisfactory,                full-time performance of such duties. Any determination of Disability                hereunder shall be made by the Board of Directors in good faith and                on the                basis of the certificates of a majority of at least three (3) qualified                physicians chosen by it for such purpose, one (1) of whom shall be                the                Executive’s regular attending                physician. |
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| (vii)   | “Notice                of Termination” shall mean a written notice which shall include the                specific termination provision under this Agreement relied upon,                and shall                set forth in reasonable detail the facts and circumstances claimed                to                provide a basis for termination of the Executive’s employment. Any                purported termination of the Executive’s employment hereunder by action of                either party shall be communicated by delivery of a Notice of Termination                to the other party. Any purported termination of the Executive’s                employment hereunder which is not effected in accordance with the                foregoing shall be ineffective for purposes of this                Agreement. |
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| (viii)   | “Retirement”                shall mean termination of the Executive’s employment pursuant to the                Company’s regular retirement policy applicable to the position held by the                Executive at the time of such                termination. |
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| (b)   | Termination                or Failure to Extend by Company Not for Cause Prior to a Change of                Control.                In the event the Executive’s employment hereunder is terminated by action                of the Company without cause prior to, but not coincident with, a                Change                of Control, or this Agreement is not extended by the Company without                cause                prior to, but not coincident with, a Change in Control, the Executive                shall be entitled to receive payments under this Agreement as though                the                Agreement was in effect through the end of the period set forth in                Paragraph 2 hereof, including any automatic extensions in effect                as of the                date of such termination. Any such payments due shall be paid on                a monthly                basis, subject to withholding and FICA and other applicable adjustments,                in accordance with the normal payroll practices of the Company. Executive                acknowledges that such payments serve as total satisfaction of Executive’s                claims under this Agreement. |
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| (c)   | Termination                By the Company at any time For Cause or by the Executive Prior to                a Change                in Control.                In the event the Executive’s employment hereunder is terminated (A) by                action of the Company for Cause either before, coincident with, or                after a                Change in Control; (B) by action of the Executive prior to, but not                coincident with, a Change in Control; or (C) by reason of the Executive’s                death, disability or retirement prior to a Change in Control, the                following compensation and benefits shall be paid and provided the                Executive (or his beneficiary): |
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| (1)   | The                Executive’s base salary provided under Paragraph 5(a) through the last day                of the month in which the Date of Termination occurs, at the annual                rate                in effect at the time Notice of Termination is given (or death occurs),                to                the extent unpaid prior to such Date of                Termination; |
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| (2)   | The                pro rata portion of any incentive or bonus payment under Paragraph                5(b)                which has been earned prior to the Date of Termination, to the extent                unpaid prior to such date; |
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| (3)   | Any                benefits to which the Executive (or his beneficiary) may be entitled                as a                result of such termination (or death), under the terms and conditions                of                the pertinent plans or arrangements in effect at the time of the                Notice of                Termination under Paragraph 5(d);                and |
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| (4)   | Any                amounts due the Executive with respect to paragraph (c) of Section                5 as of                the Date of Termination. |
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| (d)   | Termination                by Company Not For Cause Coincident With or Following a Change in                Control                or by Executive Coincident With or Following a Change in                Control.                In the event that coincident with or following a Change in Control,                the                Executive’s employment hereunder is terminated or this Agreement is not                extended (A) by action of the Executive coincident with or following                a                Change in Control including the Executive’s death, disability or                retirement, or (B) by action of the Company not for cause coincident                with                or following a Change in Control, the Company shall pay and provide                the                Executive, subject to Company regulatory limitations, the compensation                and                benefits stipulated under sub-paragraph (c) immediately above; provided,                however, in addition thereto, the following compensation and benefits                shall be paid and provided the                Executive: |
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| (e)   | Continuation                of Benefits.                Following the termination of Executive’s employment hereunder, the                Executive shall have the right to continue in the Company’s group health                insurance plan or other Company benefit program as may be required                by                COBRA or any other federal or state law or                regulation. |
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| (f)   | Compensation                During Disability.                In the event of the Executive’s failure to satisfactorily perform his                duties hereunder on a full-time basis by reason of his incapacity                due to                physical or mental illness for any period not otherwise constituting                Disability as defined under sub-paragraph (vi) of Paragraph 7(a)                hereof,                the Executive’s employment hereunder shall not be deemed terminated and he                shall continue to receive the compensation and benefits provided                under                Paragraph 5 in accordance with the terms                thereof. |
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| 8.   | Withholding.                Any provision of this Agreement to the contrary notwithstanding,                all                payments made by the Company hereunder to the Executive or his estate                or                beneficiaries shall be subject to the withholding of such amounts,                if any,                relating to tax and other payroll deductions as the Company may reasonably                determine should be withheld pursuant to any applicable law or regulation.                In lieu of withholding such amounts, the Company may accept other                provisions, provided that it has sufficient funds to pay all taxes                required by law to be withheld in respect of any or all such                payments. |
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| 9.   | Notices.                All notices, requests, demands and other communications provided                for by                this Agreement shall be in writing and shall be sufficiently given                if and                when mailed in the continental United States by registered or certified                mail, or personally delivered to the party entitled thereto, at the                address stated below or to such changed address as the addressee                may have                given by a similar notice: |
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| To                the Company: |   | President                                      |
|--------------------------------|--------|------------------------------------------------|
|                           |   | Provectus                Pharmaceuticals, Inc. |
|                           |   | 7327                Oak Ridge Highway, Suite A |
|                           |   | Knoxville,                TN 37931             |

| To                the Executive: |   | H.                Craig Dees, Ph.D.                                                     |
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|                             |   | C/o                Provectus Pharmaceuticals, Inc.7327                Oak Ridge Highway |
|                             |   | Knoxville,                Tennessee 37931                                               |
|                             |   |                                                                                    |

| 10.   | Successors:                Binding Agreement.                The Company shall require any successor (whether direct or indirect,                by                purchase, merger, consolidation or otherwise) to all or substantially                all                of the business and/or assets of the Company, by agreement in the                form and                substance satisfactory to the Executive, to expressly assume and                agree to                perform this Agreement in the same manner and to the same extent                that the                Company would be required to perform it if no such succession had                taken                place. Failure of the Company to obtain such agreement prior to the                effectiveness of any such succession shall be a breach of this Agreement.                For purposes of this Agreement, “Company” shall include any successor to                its business and/or assets as aforesaid which executes and delivers                the                agreement provided for in this Section or which otherwise becomes                bound by                all the terms and provisions of this Agreement by operation of                law. |
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| 11.   | Modification,                Waiver or Discharge.                No provision of this Agreement may be modified, waived or discharged                unless such waiver, modification or discharge is agreed to in writing                signed by the Executive and an authorized officer of the Company.                No                waiver by either party hereto at anytime of any breach by the other                party                hereto of, or compliance with, any condition or provision of this                Agreement to be performed by such other party shall be deemed a waiver                of                similar or dissimilar provisions or conditions at the same or at                any prior                or subsequent time. No agreements or representations, oral or otherwise,                express or implied, with respect to the subject matter hereof had                been                made by either party which are not expressly set forth in this Agreement;                provided, however, that this Agreement shall not supersede or in                any way                limit the right, duties or obligations that the Executive or the                Company                may have under any other written agreement between such parties,                under any                employee pension benefit plan or employee welfare benefit plan as                defined                under the Employee Retirement Income Security Act of 1974, as amended,                and                maintained by the Company, or under any established personnel practice                or                policy applicable to the Executive. |
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| 12.   | Governing                Law.                The validity, interpretation, construction and performance of this                Agreement shall be governed by the laws of the State of Tennessee                to the                extent federal law does not apply. |
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| 13.   | Validity.                The invalidity or unenforceability of any provision of this Agreement                shall not affect the validity or enforceability of the other provisions                of                this Agreement, which latter provisions shall remain in full force                and                effect. |
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| 14.   | Miscellaneous. |
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| (a)   | No                Adequate Remedy At Law; Costs to Prevailing Party.                The Company and the Executive recognize that each party may have                no                adequate remedy at law for breach by the other of any of the agreements                contained herein, and, in the event of any such breach, the Company                and                the Executive hereby agree and consent that the other shall be entitled                to                injunctive relief or other appropriate remedy to enforce performance                of                such agreements. In the event of a breach of this Agreement, then                the                prevailing party in any litigation instituted to enforce such breach                shall                have the right to recover from the losing party its costs related                thereto,                including legal fees, court costs, and any other reasonable expenses                incurred. |
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| (b)   | Non-Assignability.                No right, benefit, or interest hereunder shall be subject to anticipation,                alienation, sale, assignment, encumbrance, charge, pledge, hypothecation,                or setoff in respect of any claim, debt or obligation, or to execution,                attachment, levy or similar process, or assignment by operation of                law.                Any attempt, voluntary or involuntary, to effect any action specified                in                the immediately preceding sentence shall, to the full extent permitted                by                law, be null, void and of no effect. Any of the foregoing to the                contrary                notwithstanding, this provision shall not preclude the Executive                from                designating one or more beneficiaries to receive any amount that                may be                payable after his death, and shall not preclude the legal representative                of the Executive’s estate from assigning any right hereunder to the person                or persons entitled thereto under his will or, in the case of intestacy,                applicable to his estate. |
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| 15.   | Counterparts.                This Agreement may be executed in one or more counterparts, each                of which                shall be deemed to be an original, but of which together will constitute                one and the same instrument. |
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**IN      WITNESS WHEREOF**

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|          | **PROVECTUS              PHARMACEUTICALS, INC**.                                                                 |
|     |                                                                                                        |                                                |
| Attest:  | By:                                                                                                    | /s/ Timothy              C. Scott, Ph.D., President |
|          |                                                                                                                  |
|          | EXECUTIVE  /s/                H. Craig Dees, Ph.D.,                CEO________________________________ |