<TABLE> <S> <C>

<ARTICLE>                                           9
<CIK>                                               0000768532
<NAME>                                           First Commerce Bancshares, Inc.
<MULTIPLIER>                                                  1000

<S>                                                 <C>
<PERIOD-TYPE>                                       12-mos
<FISCAL-YEAR-END>                                   Dec-31-1999
<PERIOD-START>                                      Jan-01-1999
<PERIOD-END>                                        Dec-31-1999
<CASH>                                                     151,619
<INT-BEARING-DEPOSITS>                                           0
<FED-FUNDS-SOLD>                                            36,075
<TRADING-ASSETS>                                                 0
<INVESTMENTS-HELD-FOR-SALE>                                588,944
<INVESTMENTS-CARRYING>                                     226,748
<INVESTMENTS-MARKET>                                       221,270
<LOANS>                                                  1,441,013
<ALLOWANCE>                                                 24,952
<TOTAL-ASSETS>                                           2,609,590
<DEPOSITS>                                               1,812,856
<SHORT-TERM>                                               260,650
<LIABILITIES-OTHER>                                         36,869
<LONG-TERM>                                                241,552
<PREFERRED-MANDATORY>                                            0
<PREFERRED>                                                      0
<COMMON>                                                     2,668
<OTHER-SE>                                                 254,995
<TOTAL-LIABILITIES-AND-EQUITY>                           2,609,590
<INTEREST-LOAN>                                            114,157
<INTEREST-INVEST>                                           51,835
<INTEREST-OTHER>                                             5,062
<INTEREST-TOTAL>                                           171,054
<INTEREST-DEPOSIT>                                          61,162
<INTEREST-EXPENSE>                                          83,132
<INTEREST-INCOME-NET>                                       87,922
<LOAN-LOSSES>                                                6,877
<SECURITIES-GAINS>                                           4,625
<EXPENSE-OTHER>                                            108,873
<INCOME-PRETAX>                                             47,556
<INCOME-PRE-EXTRAORDINARY>                                  30,927
<EXTRAORDINARY>                                                  0
<CHANGES>                                                        0
<NET-INCOME>                                                30,927
<EPS-BASIC>                                                   2.33
<EPS-DILUTED>                                                 2.33
<YIELD-ACTUAL>                                                3.97
<LOANS-NON>                                                    986
<LOANS-PAST>                                                 1,124
<LOANS-TROUBLED>                                             1,224
<LOANS-PROBLEM>                                              9,474
<ALLOWANCE-OPEN>                                            24,292
<CHARGE-OFFS>                                                9,209
<RECOVERIES>                                                 2,992
<ALLOWANCE-CLOSE>                                           24,952
<ALLOWANCE-DOMESTIC>                                        24,952
<ALLOWANCE-FOREIGN>                                              0
<ALLOWANCE-UNALLOCATED>                                        197


</TABLE>