# Guide for HIV/AIDS Clinical Care
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**U.S. Department of Health and Human Services Health Resources and Services Administration				HIV/AIDS Bureau**

***Published January 2011***

This manual was developed to provide HIV/AIDS clinicians with ready access to practical, current, treatment information so that they may provide quality care to people living with HIV. 

Written and edited by expert clinicians who are part of the Ryan White HIV/AIDS Program (RWP) system, this document reflects the broad clinical expertise within the RWP. 

Individual chapters are linked to related Health Resources and Services Administration HIV/AIDS Bureau Performance Measures, and where appropriate, are based on the various Department of Health and Human Services' clinical guidelines panels' recommendations. 
- Introduction
- Editors and Contributors
- Section 1: The HIV Clinic: Providing Quality Care   - Supporting Patients in Care
  - Clinic Management
  - Quality Improvement
  - Health Resources and Services Administration HIV/AIDS Bureau Performance Measures
  - HIV Care in Correctional Settings
  - Patient Education
- Section 2: Testing and Assessment   - Initial History
  - Initial Physical Examination
  - Initial and Interim Laboratory and Other Tests
  - Interim History and Physical Examination
  - HIV Classification: CDC and WHO Staging Systems
  - CD4 Monitoring and Viral Load Testing
  - Risk of HIV Progression/Indications for ART
  - Primary HIV Infection
  - Rapid HIV Testing
  - Resistance Testing
  - Karnofsky Performance Scale
- Section 3: Health Care Maintenance and Disease Prevention   - Occupational Postexposure Prophylaxis
  - Nonoccupational Postexposure Prophylaxis
  - Preventing HIV Transmission / Prevention with Positives
  - Immunizations for HIV-Infected Adults and Adolescents
  - Preventing Exposure to Opportunistic and Other Infections
  - Opportunistic Infection Prophylaxis
  - Latent Tuberculosis Infection
  - Smoking Cessation
  - Nutrition
- Section 4: HIV Treatment   - Antiretroviral Therapy
  - Reducing Maternal-Infant HIV Transmission
  - Care of HIV-Infected Pregnant Women
  - Health Care of HIV-Infected Women through the Life Cycle
  - Palliative Care and HIV
  - Adherence
- Section 5: Common Complaints   - Diarrhea
  - Ear, Nose, Sinus, Mouth
  - Esophageal Problems
  - Eye Problems
  - Fatigue
  - Fever
  - Headache
  - Lymphadenopathy
  - Nausea and Vomiting
  - Neurologic Symptoms
  - Pulmonary Symptoms
  - Vaginitis/Vaginosis
- Section 6: Comorbidities, Coinfections and Complications   - Abnormalities of Body-Fat Distribution
  - Dyslipidemia
  - Insulin Resistance, Hyperglycemia, and Diabetes on Antiretroviral Therapy
  - Coronary Heart Disease Risk
  - Renal Disease
  - Immune Reconstitution Inflammatory Syndrome
  - Anal Dysplasia
  - Candidiasis, Oral and Esophageal
  - Candidiasis, Vulvovaginal
  - Cervical Dysplasia
  - Cryptococcal Disease
  - Cryptosporidiosis
  - Cytomegalovirus Disease
  - Gonorrhea and Chlamydia
  - Hepatitis B Infection
  - Hepatitis C Infection
  - Herpes Simplex, Mucocutaneous
  - Herpes Zoster/Shingles
  - Histoplasmosis
  - Kaposi Sarcoma
  - Molluscum Contagiosum
  - *Mycobacterium avium* Complex
  - *Mycobacterium tuberculosis*
  - Pelvic Inflammatory Disease
  - Pneumocystis Pneumonia
  - Progressive Multifocal Leukoencephalopathy
  - Seborrheic Dermatitis
  - Sinusitis
  - Syphilis
  - Toxoplasmosis
- Section 7: ARV Interactions and Adverse Events   - Adverse Reactions to HIV Medications
  - Drug-Drug Interactions with HIV-Related Medications
  - Antiretroviral Medications and Hormonal Contraceptive Agents
- Section 8: Neuropsychiatric Disorders   - Pain Syndrome and Peripheral Neuropathy
  - HIV-Associated Dementia and Other Neurocognitive Disorders
  - Major Depression and Other Depressive Disorders
  - Suicide Risk
  - Anxiety Disorders
  - Panic Disorder
  - Posttraumatic Stress Disorder
  - Insomnia
- Section 9: Oral Health   - Oral Health
  - Oral Ulceration
  - Oral Warts
  - Oral Hairy Leukoplakia
  - Necrotizing Ulcerative Periodontitis and Gingivitis
- Section 10: Resources and References   - Web-Based Resources
  - Sulfa Desensitization
  - Antiretrovirals Available in the United States and Mexico
  - Antiretroviral Reference Tables
Attribution
This publication was funded by the U.S. Health Resources and Services Administration, HIV/AIDS Bureau, under contract number HHSH231200533009C with WriteProcess, Inc. and the AETC National Resource Center.

U.S. Department of Health and Human Services Health Resources and Services AdministrationHIV/AIDS BureauParklawn Building, Room 7-055600 Fishers Lane Rockville, MD 20857