### Cover Letter

June 18, 2012

By Central Data Exchange

New Chemicals Program Office of Pollution Prevention and Toxics Confidential Business Information Center [Rm. 6428] EPA East Building Ronald Reagan Complex 1201 Constitution Ave., NW Washington, DC 20004-3302

Re: Premanufacture Notice Submission under TSCA Section 5 by Kowa American Corporation

Dear Sir/Madam: Enclosed you will find a Premanufacture Notice (PMN) submitted under Section 5(a)(1) of the Toxic Substances Control Act (TSCA). This PMN is being submitted to the U.S. Environmental Protection Agency (EPA or the Agency) by Kowa American Corporation (Kowa or the Company) for the chemical substance identified below: CA Index Name: 2-Propenoic acid, (2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl ester CAS Registry Number: 69701-99-1 Trade Name: Medol-10 TS Number: UVCA02 This PMN submission is made in accordance with the regulations given at 40 CFR 720. We request that the Agency begin review upon receipt. This PMN has been created using the EPA’s new e-PMN software and, as now required under EPA regulations, this notice is being submitted through EPA's Central Data Exchange (CDX).

Page 1 SANITIZED SUBMISSIONAt this time, Kowa is also remitting a check in the amount $2,500.00 for the PMN user fee in accordance with the

requirements at 40 CFR 700.45(b)(1). This check is being sent to EPA’s Washington Finance Center in St. Louis, MO. Finally, Kowa is claiming certain information in the PMN as Confidential Business Information (CBI) in accordance with the provisions at 40 CFR 720.80. The Company, however, is not claiming either the chemical identity or company identity as CBI. For all questions regarding the submission of this PMN, the technical contact is Mr. John V. Massingale of Greenwich Chemical Consulting, Inc. He is reachable at (561) 578-8110.
Sincerely,

Mark Smith Sales Manager

cc: John V. Massingale - Greenwich Chemical Consulting, Inc.

Page 2 SANITIZED SUBMISSIONCheck No.: 2937 MEDO120618360734668 UVCA02

X X X X X

X

X
Page 3 SANITIZED SUBMISSIONX

Page 4 SANITIZED SUBMISSIONmark smith Sales Manager Kowa American Corp. 55 East 59th Street, 19th Floor New York NY 10022 mark@kowa.com
John Massingale Principal Greenwich Chemical Consulting, Inc. 3300 PGA Blvd., Suite 635 Palm Beach Gardens FL 33410 john@grcci.com 561-578-8110

John Massingale Principal Greenwich Chemical Consulting, Inc. 3300 PGA Blvd., Suite 635 Palm Beach Gardens FL 33410 john@grcci.com 561-578-8110 

### X
X
X X XXX

XXX

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Page 5 SANITIZED SUBMISSION

### X

2-Propenoic acid, (2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl ester

69701-99-1 

### X 89172 Attachment-3-CBI.pdf C10 H16 O4

See Attachment 003 (Attachment-3-CBI.pdf)

Attachment-3-CBI.pdf

Page 6 SANITIZED SUBMISSIONPage 7 SANITIZED SUBMISSIONPage 8 SANITIZED SUBMISSIONPage 9 SANITIZED SUBMISSION(2-Ethyl-2-methyl-1,3-dioxolan-4-yl)methyl acrylate

(2-Methyl-2-ethyl-1,3-dioxolan-4-yl)methyl acrylate

Medol-10 2-Propenoic acid 79-10-7 0.01 1,3-Dioxolane-4-methanol, 2-ethyl-2-methyl- 3842-72-6 0.1 Water 7732-18-5 0.1 4-Methoxy phenol (inhibitor) 150-76-5 0.02

None.

Page 10 SANITIZED SUBMISSIONXXX XXX 

### X

X Reactive intermediate for use in UV, EB and conventionally cured coating and ink formulations [open/non-dispersive use]. 100 100 XXX XXX XXX XXX X

Page 11 SANITIZED SUBMISSIONSee Attachment #4.

Page 12 SANITIZED SUBMISSIONSee Attachment 004 (Attachment-4-CBI.pdf)

Attachment-4-CBI.pdf

Page 13 SANITIZED SUBMISSIONPage 14 SANITIZED SUBMISSIONPage 15 SANITIZED SUBMISSION

### X

See Attachment 007 (Attachment-7-SAN.pdf)

Attachment-7-SAN.pdf See Attachment #7.

Page 16 SANITIZED SUBMISSIONP10SB1(a)(4)1 Part II, Section B, 1(a)(4). Operation Site Locations

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Page 17 SANITIZED SUBMISSIONXXX 

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### (1)

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X X X

Page 19 SANITIZED SUBMISSIONThe new chemical substance has the following pollution prevention advantages:

(1) The new chemical substance will function as a reactive monomer and will be used as a component in an ultraviolet (UV), electron beam (EB), and conventionally cured coating and ink formulations. UV and EB light curable formulations replace traditional solvent-based resin systems and, therefore, reduce or eliminate the use of solvents. As importantly, UV and EB curing operations are also less energy intensive than traditional thermal cure systems and have reduced chemical usage. (2) The new chemical substance will be used as replacement compound for tetrahydrofurfuryl acrylate (THFA) which is currently used in UV and EB applications as a diluent solvent. THFA is a compound with relatively high skin irritation, as well as a strong, offensive odor and high vapor pressure. The new chemical substance has a low skin irritation index (PII = 1.3). In addition, the new chemical substance is less flammable (flash point = 113 °C) than THFA (flash point = 95 °C). The new chemical substance is the only known replacement for THFA. (3) The new chemical substance is a relatively high priced monomer that is expected to be used only in sophisticated, high-end applications (e.g., electronics, solar cells, UV inkjet devices, etc.). This necessarily means that exposure and release will be limited. It is not expected to be used in common printing or high volume applications. Moreover, the compound is never expected to be the primary monomer in coating and ink formulations.

Page 20 SANITIZED SUBMISSION001 Material Safety Data Sheet Attachment-1-CBI.pdf 13

002 Summary of Information on the New Chemical Substance Attachment-2-CBI.pdf 1 003 CAS Inventory Expert Service Report and Chemical Structure of the New Chemical Attachment-3-CBI.pdf Pt.I, Sec.B, 1c. | Pt.I, Sec.B, 1e. 3
004 Manufacturing and Processing Information on the New Chemical Substance at Industrial Sites Attachment-4-CBI.pdf Pt.2, Sec.A, 1d. 1 005 Worker/Occupational Exposure Information on the New Chemical Substance at Industrial Sites Attachment-5-CBI.pdf 1 006 Environmental Release and Disposal Information on the New Chemical Substance at Industrial Attachment-6-CBI.pdf 1 007 Processing Information on the New Chemical Substance at Industrial Sites Controlled by Attachment-7-SAN.pdf Pt.2, Sec.B, 1a. 2 008 Worker/Occupational Exposure and Environmental Release Information on the New Attachment-8-SAN.pdf 1 009 Environmental Fate Data on the New Chemical Substance - Biodegradation Test Attachment-9-CBI.pdf 61 010 Health Effects Data on the New Chemical Substance - Skin Irritation Test Attachment-10-CBI.pdf 22 011 Health Effects Data on the New Chemical Substance - Ames Test-1 Attachment-11-CBI.pdf 18
012 Health Effects Data on the New Chemical Attachment-12-CBI.pdf 6 013 Other Data Not in the Possession or Control of the Submitter Attachment-13-SAN.pdf 1

Page 21 SANITIZED SUBMISSION

### X 0.02 (MPBPWIN) Estimate 25 1.056 Measured

12.9 Measured 20

100 Measured 5.3

1.92 Measured

Flash point = 113 C Measured

5.1 mPa-Sec (20 C) Measured Viscosity

Page 22 SANITIZED SUBMISSIONSurface tension 32.3 dynes/cm Measured

Page 23 SANITIZED SUBMISSION

### ATTACHMENT HEADER SHEET

Attachment Number 001 Attachment Name Material Safety Data Sheet 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 002 Attachment Name Summary of Information on the New Chemical Substance 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 003 Attachment Name CAS Inventory Expert Service Report and Chemical Structure of the New Chemical



### Associated PMN Section Number Pt.I, Sec.B, 1c. | Pt.I, Sec.B, 1e.
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 004 Attachment Name Manufacturing and Processing Information on the New Chemical Substance at Industrial Sites Controlled by the Submitter 

### Associated PMN Section Number

Pt.2, Sec.A, 1d.
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 005 Attachment Name Worker/Occupational Exposure Information on the New Chemical Substance at Industrial Sites Controlled by the Submitter 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 006 Attachment Name Environmental Release and Disposal Information on the New Chemical Substance at Industrial Sites Controlled by the Submitter 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 007 Attachment Name Processing Information on the New Chemical Substance at Industrial Sites Controlled by Others 

### Associated PMN Section Number

Pt.2, Sec.B, 1a.
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 008 Attachment Name Worker/Occupational Exposure and Environmental Release Information on the New Chemical Substance at Industrial Sites Controlled by Others 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 009 Attachment Name Environmental Fate Data on the New Chemical Substance - Biodegradation Test



### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 010 Attachment Name Health Effects Data on the New Chemical Substance - Skin Irritation Test



### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 011 Attachment Name Health Effects Data on the New Chemical Substance - Ames Test-1



### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 012 Attachment Name Health Effects Data on the New Chemical Substance - Ames Test-2



### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668

### ATTACHMENT HEADER SHEET

Attachment Number 013 Attachment Name Other Data Not in the Possession or Control of the Submitter 

### Associated PMN Section Number

N/A
Does not contain CBI 

### Report Number MEDO120618360734668