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U. S. SECURITIES AND EXCHANGE COMMISSION

Washington, D. C. 20549



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FORM 10-Q



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QUARTERLY REPORT PURSUANT TO

SECTION 13 or 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

For the quarter ended March 31, 2006

Commission File No. 0-28780



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CARDINAL BANKSHARES CORPORATION

(Exact name of registrant as specified in its charter)



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|                         |  |                                     
|------------------------ |  | ------------------------------------
|Virginia                 |  | 54-1804471                          
|(State of Incorporation) |  | (I.R.S. Employer Identification No.)

101 Jacksonville Circle, P. O. Box 215, Floyd, Virginia 24091

(Address of principal executive offices)

(540) 745-4191

(Registrants telephone number)



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Indicate by check mark whether the registrant
(1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and
(2) has been subject to such filing requirements for the past 90 days.    Yes  x.    No ̈.

Indicate by check mark whether the registrant is a large accelerated filer, an
accelerated filer, or a non-accelerated filer. (Check one):

Large Accelerated Filer ̈Accelerated Filer ̈Non-accelerated Filer  x.

Indicate by check mark
whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes ̈.    No  x.

The number of shares outstanding of
the issuers Common Stock, $10 par value as of May 12, 2006 was 1,535,733.



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##### Table of Contents

CARDINAL BANKSHARES CORPORATION

FORM 10-Q

March 31, 2006

INDEX



|         |  |                                                                                                      |  |     
|-------- |  | ---------------------------------------------------------------------------------------------------- |  | ----
|         |  |                                                                                                      |  | Page
|Part I.  |  | Financial Information                                                                                |  |     
|         |  |                                                                                                     
|Item 1.  |  | Consolidated Balance Sheets as of March 31, 2006 (Unaudited) and December 31, 2005 (Audited)         |  | 3   
|         |  |                                                                                                     
|         |  | Consolidated Statements of Income for the three months ended March 31, 2006 and 2005 (Unaudited)     |  | 4   
|         |  |                                                                                                     
|         |  | Consolidated Statements of Cash Flows for the three months ended March 31, 2006 and 2005 (Unaudited) |  | 5   
|         |  |                                                                                                     
|         |  | Notes to Consolidated Statements (Unaudited)                                                         |  | 6   
|         |  |                                                                                                     
|Item 2.  |  | Managements Discussion and Analysis of Financial Condition and Results of Operations                |  | 7   
|         |  |                                                                                                     
|Item 3.  |  | Quantitative and Qualitative Disclosures About Market Risk                                           |  | 10  
|         |  |                                                                                                     
|Item 4.  |  | Controls and Procedures                                                                              |  | 11  
|         |  |                                                                                                     
|Part II. |  | Other Information                                                                                    |  |     
|         |  |                                                                                                     
|Item 1.  |  | Legal Proceedings                                                                                    |  | 12  
|         |  |                                                                                                     
|Item 1A. |  | Risk Factors                                                                                         |  | 13  
|         |  |                                                                                                     
|Item 2.  |  | Unregistered Sales of Equity Securities and Use of Proceeds                                          |  | 13  
|         |  |                                                                                                     
|Item 3.  |  | Defaults Upon Senior Securities                                                                      |  | 13  
|         |  |                                                                                                     
|Item 4.  |  | Submission of Matters to a Vote of Security Holders                                                  |  | 13  
|         |  |                                                                                                     
|Item 5.  |  | Other Information                                                                                    |  | 13  
|         |  |                                                                                                     
|Item 6.  |  | Exhibits                                                                                             |  | 13  



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##### Table of Contents

Cardinal Bankshares Corporation and Subsidiary

Consolidated Balance Sheets



|                                                                                                          |  |                          |         |   |                           |   |         |  
|--------------------------------------------------------------------------------------------------------- |  | ------------------------ | ------- | - | ------------------------- | - | ------- | -
|(In thousands, except share data)                                                                         |  | (Unaudited)March 31,2006 |         |   | (Audited)December31, 2005 |  
|Assets                                                                                                    |  |                          |         |   |                           |   |         |  
|                                                                                                          |  |                         
|Cash and due from banks                                                                                   |  | $                        | 3,001   |   |                           | $ | 4,292   |  
|Interest-bearing deposits                                                                                 |  |                          | 9,748   |   |                           |   | 9,042   |  
|Federal funds sold                                                                                        |  |                          | 1,575   |   |                           |   | 5,125   |  
|Investment securities available for sale, at fair value                                                   |  |                          | 19,663  |   |                           |   | 19,308  |  
|Investment securities held to maturity (fair value March 31, 2006 - $18,073; December 31, 2005 - $17,743) |  |                          | 17,841  |   |                           |   | 17,470  |  
|Restricted equity securities                                                                              |  |                          | 554     |   |                           |   | 546     |  
|                                                                                                          |  |                         
|Total loans                                                                                               |  |                          | 129,359 |   |                           |   | 129,981 |  
|Allowance for loan losses                                                                                 |  |                          | (1,444  | ) |                           |   | (1,427  | )
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Net loans                                                                                                 |  |                          | 127,915 |   |                           |   | 128,554 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Bank premises and equipment, net                                                                          |  |                          | 3,917   |   |                           |   | 3,997   |  
|Accrued interest receivable                                                                               |  |                          | 985     |   |                           |   | 998     |  
|Foreclosed properties                                                                                     |  |                          | 418     |   |                           |   | 418     |  
|Bank owned life insurance                                                                                 |  |                          | 4,669   |   |                           |   | 4,631   |  
|Other assets                                                                                              |  |                          | 1,601   |   |                           |   | 1,854   |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Total assets                                                                                              |  | $                        | 191,887 |   |                           | $ | 196,235 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Liabilities and Stockholders' Equity                                                                      |  |                          |         |   |                           |   |         |  
|                                                                                                          |  |                         
|Noninterest-bearing deposits                                                                              |  | $                        | 27,347  |   |                           | $ | 26,747  |  
|Interest-bearing deposits                                                                                 |  |                          | 135,585 |   |                           |   | 141,101 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Total deposits                                                                                            |  |                          | 162,932 |   |                           |   | 167,848 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Securities sold under agreements to repurchase                                                            |  |                          |        |   |                           |   | 134     |  
|Accrued interest payable                                                                                  |  |                          | 142     |   |                           |   | 134     |  
|Other liabilities                                                                                         |  |                          | 1,102   |   |                           |   | 1,061   |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Total liabilities                                                                                         |  |                          | 164,176 |   |                           |   | 169,177 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Commitments and contingent liabilities                                                                    |  |                          |        |   |                           |   |        |  
|                                                                                                          |  |                         
|Stockholders' Equity                                                                                      |  |                          |         |   |                           |   |         |  
|                                                                                                          |  |                         
|Common stock, $10 par value, 5,000,000 shares authorized, 1,535,733 shares issued and outstanding         |  |                          | 15,357  |   |                           |   | 15,357  |  
|Additional paid-in capital                                                                                |  |                          | 2,925   |   |                           |   | 2,925   |  
|Retained earnings                                                                                         |  |                          | 9,496   |   |                           |   | 8,833   |  
|Accumulated other comprehensive income, net                                                               |  |                          | (67     | ) |                           |   | (57     | )
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Total stockholders' equity                                                                                |  |                          | 27,711  |   |                           |   | 27,058  |  
|                                                                                                          |  |                          |         |   |                           |   |         |  
|Total liabilities and stockholders' equity                                                                |  | $                        | 191,887 |   |                           | $ | 196,235 |  
|                                                                                                          |  |                          |         |   |                           |   |         |  

See Notes to Consolidated Financial Statements.



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Cardinal Bankshares Corporation and Subsidiary

Consolidated Statements of Income (Unaudited)



|                                                                       |  |                             |           |      |   |          
|---------------------------------------------------------------------- |  | --------------------------- | --------- | ---- | - | ---------
|                                                                       |  | Three months endedMarch 31,
|(In thousands, except share data)                                      |  | 2006                        |           | 2005
|Interest income                                                        |  |                             |           |      |   |          
|                                                                       |  |                            
|Loans and fees on loans                                                |  | $                           | 2,316     |      | $ | 2,002    
|Federal funds sold and securities purchased under agreements to resell |  |                             | 27        |      |   | 26       
|Investment securities:                                                 |  |                             |           |      |   |          
|Taxable                                                                |  |                             | 192       |      |   | 210      
|Exempt from federal income tax                                         |  |                             | 218       |      |   | 239      
|Deposits with banks                                                    |  |                             | 111       |      |   | 17       
|                                                                       |  |                             |           |      |   |          
|Total interest income                                                  |  |                             | 2,864     |      |   | 2,494    
|                                                                       |  |                             |           |      |   |          
|Interest expense                                                       |  |                             |           |      |   |          
|                                                                       |  |                            
|Deposits                                                               |  |                             | 969       |      |   | 775      
|Securities Sold                                                        |  |                             |          |      |   | 12       
|                                                                       |  |                             |           |      |   |          
|Total interest expense                                                 |  |                             | 969       |      |   | 787      
|                                                                       |  |                             |           |      |   |          
|Net interest income                                                    |  |                             | 1,895     |      |   | 1,707    
|Provision for loan losses                                              |  |                             | 20        |      |   | 24       
|                                                                       |  |                             |           |      |   |          
|Net interest income after provision for loan losses                    |  |                             | 1,875     |      |   | 1,683    
|                                                                       |  |                             |           |      |   |          
|Noninterest income                                                     |  |                             |           |      |   |          
|                                                                       |  |                            
|Service charges on deposit accounts                                    |  |                             | 68        |      |   | 58       
|Other service charges and fees                                         |  |                             | 23        |      |   | 23       
|Net realized gains on sales of securities                              |  |                             | 3         |      |   | 3        
|Other operating income                                                 |  |                             | 130       |      |   | 85       
|                                                                       |  |                             |           |      |   |          
|Total noninterest income                                               |  |                             | 224       |      |   | 169      
|                                                                       |  |                             |           |      |   |          
|Noninterest expense                                                    |  |                             |           |      |   |          
|                                                                       |  |                            
|Salaries and employee benefits                                         |  |                             | 747       |      |   | 683      
|Occupancy and equipment                                                |  |                             | 173       |      |   | 192      
|Other operating expense                                                |  |                             | 307       |      |   | 311      
|                                                                       |  |                             |           |      |   |          
|Total noninterest expense                                              |  |                             | 1,227     |      |   | 1,186    
|                                                                       |  |                             |           |      |   |          
|Income before income taxes                                             |  |                             | 872       |      |   | 666      
|Income tax expense                                                     |  |                             | 209       |      |   | 140      
|                                                                       |  |                             |           |      |   |          
|Net Income                                                             |  | $                           | 663       |      | $ | 526      
|                                                                       |  |                             |           |      |   |          
|Basic earnings per share                                               |  | $                           | 0.43      |      | $ | 0.34     
|Diluted earnings per share                                             |  | $                           | 0.43      |      | $ | 0.34     
|Weighted average basic shares outstanding                              |  |                             | 1,535,733 |      |   | 1,535,733
|Weighted average diluted shares outstanding                            |  |                             | 1,535,733 |      |   | 1,535,733
|                                                                       |  |                             |           |      |   |          

See Notes to Consolidated Financial Statements.



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Cardinal Bankshares Corporation and Subsidiary

Consolidated Statements of Cash Flows (Unaudited)



|                                                                                  |  |      |        |   |      |   |        |  
|--------------------------------------------------------------------------------- |  | ---- | ------ | - | ---- | - | ------ | -
|(In thousands) Three Months Ended March 31,                                       |  | 2006 |        |   | 2005 |  
|Cash flows from operating activities                                              |  |      |        |   |      |   |        |  
|Net income                                                                        |  | $    | 663    |   |      | $ | 526    |  
|Adjustments to reconcile net income to net cash provided by operating activities: |  |      |        |   |      |   |        |  
|Depreciation and amortization                                                     |  |      | 85     |   |      |   | 92     |  
|Net amortization (accretion) of bond premiums/discounts                           |  |      | 7      |   |      |   | 5      |  
|Provision for loan losses                                                         |  |      | 20     |   |      |   | 24     |  
|Net realized (gains) losses on investment securities                              |  |      | (3     | ) |      |   | (3     | )
|Deferred compensation and pension expense                                         |  |      | 64     |   |      |   | 51     |  
|Changes in operating assets and liabilities:                                      |  |      |        |   |      |   |        |  
|(Increase) decrease in accrued interest receivable                                |  |      | 13     |   |      |   | 17     |  
|Increase (decrease) in accrued interest payable                                   |  |      | 8      |   |      |   | 26     |  
|Net change in other operating assets and liabilities                              |  |      | 198    |   |      |   | (113   | )
|                                                                                  |  |      |        |   |      |   |        |  
|Net cash provided by operating activities                                         |  |      | 1,055  |   |      |   | 625    |  
|                                                                                  |  |      |        |   |      |   |        |  
|Cash flows from investing activities                                              |  |      |        |   |      |   |        |  
|Net (increase) decrease in interest-bearing deposits in banks                     |  |      | (706   | ) |      |   | 2,546  |  
|Net (increase) decrease in federal funds sold                                     |  |      | 3,550  |   |      |   | 4,725  |  
|Purchase of investment securities                                                 |  |      | (1,688 | ) |      |   | (1,778 | )
|Proceeds from sale of available for sale securities                               |  |      |       |   |      |   | 750    |  
|Purchase of restricted equity securities                                          |  |      | (8     | ) |      |   |       |  
|Proceeds from redemption of equity securities                                     |  |      |       |   |      |   | 57     |  
|Proceeds from maturity and redemption of investment securities                    |  |      | 942    |   |      |   | 2,251  |  
|Sale of foreclosed properties                                                     |  |      |       |   |      |   |       |  
|Net (increase) decrease in loans                                                  |  |      | 619    |   |      |   | (4,171 | )
|Net purchases of bank premises and equipment                                      |  |      | (5     | ) |      |   | (60    | )
|                                                                                  |  |      |        |   |      |   |        |  
|Net cash (used) provided by investing activities                                  |  |      | 2,704  |   |      |   | 4,320  |  
|                                                                                  |  |      |        |   |      |   |        |  
|Financing Activities                                                              |  |      |        |   |      |   |        |  
|Net increase (decrease) in noninterest-bearing deposits                           |  |      | 600    |   |      |   | (261   | )
|Net (decrease) in interest-bearing deposits                                       |  |      | (5,516 | ) |      |   | (3,218 | )
|Net increase (decrease) in securities sold                                        |  |      | (134   | ) |      |   | (418   | )
|                                                                                  |  |      |        |   |      |   |        |  
|Net cash (used) provided by financing activities                                  |  |      | (5,050 | ) |      |   | (3,897 | )
|                                                                                  |  |      |        |   |      |   |        |  
|Net (decrease) increase in cash and cash equivalents                              |  |      | (1,291 | ) |      |   | 1,048  |  
|Cash and cash equivalents at beginning of year                                    |  |      | 4,292  |   |      |   | 4,162  |  
|                                                                                  |  |      |        |   |      |   |        |  
|Cash and cash equivalents at end of year                                          |  | $    | 3,001  |   |      | $ | 5,210  |  
|                                                                                  |  |      |        |   |      |   |        |  
|Supplemental disclosures of cash flow information                                 |  |      |        |   |      |   |        |  
|Interest paid                                                                     |  | $    | 961    |   |      | $ | 761    |  
|Income taxes paid                                                                 |  | $    |       |   |      | $ | 81     |  
|                                                                                  |  |      |        |   |      |   |        |  

See Notes to Consolidated Financial Statements.



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NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Unaudited)

Note 1. Basis of Presentation

The accompanying unaudited consolidated financial statements have been prepared in accordance with the instructions to Form 10-Q and, therefore, do not
include all of the disclosures and notes required by generally accepted accounting principles. In the opinion of management, all material adjustments (which are of a normal recurring nature) considered necessary for a fair presentation have been
made. The results for the interim period are not necessarily indicative of the results to be expected for the entire year or any other interim period. The information reported herein should be read in conjunction with the Notes to Consolidated
Financial Statements included in the Companys Annual Report on Form 10-K for the year ended December 31, 2005. Certain previously reported amounts have been reclassified to conform to current presentations.

Note 2. Allowance for Loan Losses

Changes in the allowance for loan losses are as follows:



|                                             |  |      |       |   |      |   |       |  
|-------------------------------------------- |  | ---- | ----- | - | ---- | - | ----- | -
|Three months ended March 31, (In thousands)  |  | 2006 |       |   | 2005 |  
|Balance, at January 1                        |  | $    | 1,427 |   |      | $ | 1,631 |  
|Provision charged to expense                 |  |      | 20    |   |      |   | 24    |  
|Recoveries of amounts previously charged off |  |      | 5     |   |      |   |      |  
|Loans charged off                            |  |      | (8    | ) |      |   | (20   | )
|                                             |  |      |       |   |      |   |       |  
|Balance, at March 31,                        |  | $    | 1,444 |   |      | $ | 1,635 |  
|                                             |  |      |       |   |      |   |       |  

Note 3. Commitments and Contingencies

The Companys exposure to credit loss in the event of nonperformance by the other party for commitments to extend credit and stand-by letters of credit is
represented by the contractual amount of those instruments. The Company uses the same credit policies in making commitments and conditional obligations as for on-balance sheet instruments. A summary of the Companys commitments at March 31
for the years indicated follows:



|                             |  |      |        |      |   |       
|---------------------------- |  | ---- | ------ | ---- | - | ------
|(In thousands)               |  | 2006 |        | 2005
|Commitments to extend credit |  | $    | 17,953 |      | $ | 16,161
|Standby letters of credit    |  |      | 473    |      |   | 648   
|                             |  |      |        |      |   |       
|Total                        |  | $    | 18,426 |      | $ | 16,809
|                             |  |      |        |      |   |       

Note 4. Employee Benefit Plan

The Bank has a qualified noncontributory, defined benefit pension plan which covers substantially all of its employees. The benefits are primarily based on years of
service and earnings. The following is a summary of the components of the net periodic benefit cost.



|                                             |  |      |         |   |      |   |         |  
|-------------------------------------------- |  | ---- | ------- | - | ---- | - | ------- | -
|Three months ended March 31, (In thousands)  |  | 2006 |         |   | 2005 |  
|Service cost                                 |  | $    | 58,318  |   |      | $ | 44,275  |  
|Interest cost                                |  |      | 49,051  |   |      |   | 43,907  |  
|Expected return on plan assets               |  |      | (49,062 | ) |      |   | (42,622 | )
|Amortization of net obligation at transition |  |      | (1,007  | ) |      |   | (1,007  | )
|Amortization of prior service cost           |  |      | 1,495   |   |      |   | 1,495   |  
|Amortization of net (gain) or loss           |  |      | 5,636   |   |      |   | 4,834   |  
|                                             |  |      |         |   |      |   |         |  
|Total net periodic benefit cost              |  | $    | 64,431  |   |      | $ | 50,882  |  
|                                             |  |      |         |   |      |   |         |  



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##### Table of Contents

The Company previously disclosed in its financial statements for the year ended December 31, 2005, that it expected
to contribute $258 thousand to it pension plan in 2006. As of March 31, 2006, no contributions have been made.

Item 2. MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Cardinal Bankshares
Corporation (the Company and Cardinal Bankshares), a Virginia corporation, is a bank holding company headquartered in Floyd, Virginia. The Company serves the marketplace primarily through its wholly owned banking subsidiary,
Bank of Floyd (the Bank), a Virginia chartered, Federal Reserve member commercial bank. The Banks deposits are insured by the Federal Deposit Insurance Corporation (the FDIC) to the extent provided by law. Bank of Floyd
is supervised and examined by the Federal Reserve and the Bureau of Financial Institutions of the State Corporation Commission of the Commonwealth of Virginia (the SCC). At March 31, 2006, the Bank operated seven branch facilities
in the counties of Floyd, Montgomery, Roanoke and Carroll. The main office is in Floyd with a limited service office located in Willis. The Roanoke offices are in the Cave Spring and Tanglewood Mall areas of Roanoke County. The Salem office is
located on West Main Street in Salem, Virginia. The Hillsville office is located in Carroll County. The Christiansburg office serves Montgomery County.

Through Bank of Floyds network of banking facilities, Cardinal Bankshares provides a wide range of commercial banking services to individuals, small to medium-sized businesses, institutions and governments located in Virginia. The
Company conducts substantially all of the business operations of a typical independent commercial bank, including the acceptance of checking and savings deposits, and the making of commercial, real estate, personal, home improvement, automobile and
other installment loans. The Company also offers other related services, such as travelers checks, safe deposit boxes, depositor transfer, customer note payment, collection, notary public, escrow, drive-in and ATM facilities, and other
customary banking services. Cardinal Bankshares does not offer trust services.

The following discussion provides information about the major components of
the financial condition, results of operations, asset quality, liquidity, and capital resources of Cardinal Bankshares. The discussion and analysis should be read in conjunction with the Consolidated Financial Statements.

FINANCIAL CONDITION

Total assets as of March 31, 2006 were
$191.9 million, a decrease of $4.3 million from year-end 2005. Total loans declined 0.5% or $622 thousand during the quarter to $129.3 million.

The
investment securities portfolio reflected a net increase of $726 thousand. This increase was a result of the call of one $279 thousand Municipal Security, maturity of a $245 thousand Municipal Security and usual pay downs in the amount of $418
thousand in mortgage-backed securities offset by purchases of investment securities totaling approximately $1.7 million. Federal funds sold declined approximately $3.5 million during the quarter as the Company continues to strategically reduce rate
sensitive deposit balances in light of continued moderate loan demand in its principal market area.

As of March 31, 2006, total deposits were $162.9
million, down approximately $4.9 million compared to year-end 2005. Non-interest-bearing core deposits remained level at $27.3 million as compared to $26.7 million at year-end 2005. Interest-bearing deposits declined 3.9% or $5.5 million to $135.6
million. Due to the soft loan demand in the current economic environment, the Company has strategically remained less competitive on rate sensitive deposits as reflected in the $7.3 million decline in large denomination deposits, those deposit
accounts with balances greater than $100 thousand. Deposits greater than $100 thousand amounted to $39.7 million at March 31, 2006 as compared to $47.0 million at year-end 2005.

Stockholders equity was $27.7 million as of March 31, 2006 compared to $27.1 million as of December 31, 2005. Net income for the quarter of $663 thousand principally accounted for the increase in
stockholders equity.



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##### Table of Contents

RESULTS OF OPERATIONS

Net income for the three months ended March 31, 2006 was $663 thousand, up 26.0% compared to $526 thousand for the three months ended March 31, 2005. Diluted earnings per share increased 26.5% to $.43 for the three months ended
March 31, 2006. Diluted earnings per share for the same period a year earlier was $.34.

Total interest income for the three months ended
March 31, 2006 increased $370 thousand to $2.9 million, an increase of 14.8% over the same prior year quarter. This resulted primarily from the effect of increased yields on loans with slightly increasing interest rates. The increase in
interest income was the principal contributing factor to improved profitability for the first quarter of 2006 compared to the first quarter of 2005. Noninterest income increased 32.5% to $224 thousand. Total interest expense increased $182 thousand
to $969 thousand, reflecting the effect of higher yields on interest-bearing deposits. Noninterest expense increased 3.5% to $1.2 million for the first quarter of 2006 as compared to the first quarter of 2005. The primary expense that attributed to
this noninterest expense increase was a slight increase in salaries and employee benefits as compared to the first quarter of 2005.

ASSET QUALITY

The allowance for loan losses represents managements estimate of an amount adequate to absorb potential future losses inherent in the loan
portfolio. In assessing the adequacy of the allowance, management relies predominately on its ongoing review of the lending process and the risk characteristics of the portfolio in the aggregate. Among other factors, management considers the
Companys loan loss experience, the amount of past-due loans, current and anticipated economic conditions, and the estimated current values of collateral securing loans in assessing the level of the allowance for loan losses. In the first
quarter of 2006, the provision for loan losses was $20 thousand as compared to $24 thousand provision for the same period in 2005. Based upon managements periodic reviews of the loan portfolio using the above mentioned factors, the current
year increase in the provision for loan losses was felt appropriate. Management believes the provision recorded in 2006 maintains the allowance at a level adequate to cover potential losses.

The allowance for loan losses totaled $1.4 million at March 31, 2006. The allowance for loan losses to period end loans was 1.12% at March 31, 2006 compared to
1.10% and 1.27% at December 31, 2005 and March 31, 2005, respectively. The Company charged off balances on loans in the amount of $3 thousand during the quarter. This compares with net charge offs for the three months ended March 31,
2005 of $20 thousand.

The allowance for loan losses represents managements estimate of an amount adequate to provide for potential losses inherent
in the loan portfolio. The adequacy of the loan loss reserve and the related provision are based upon managements evaluation of the risk characteristics of the loan portfolio under current economic conditions with consideration to such factors
as financial condition of the borrowers, collateral values, growth and composition of the loan portfolio, the relationship of the allowance to outstanding loans and delinquency trends.

While management uses all available information to recognize losses on loans, future additions to the allowance may be necessary based on changes in economic conditions. Various regulatory agencies, as an integral
part of their examination process, periodically review the Companys allowance for loan losses. Such agencies may require the Company to recognize additions to the allowance based on their judgments about information available to them at the
time of their examination.

Nonperforming assets, which consist of nonaccrual loans, loans 90 days or more past due, and other real estate owned, were $3.0
million as of March 31, 2006 compared to $467 thousand as of December 31, 2005. Management does not expect to incur any material losses related to nonperforming assets.



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LIQUIDITY

In
determining the Companys liquidity requirements, both sides of the balance sheet are managed to ensure that adequate funding sources are available to support loan growth, deposit withdrawals or any unanticipated need for funds.

Securities available for sale that mature within one year, or securities that have a weighted average life of one year or less are sources of liquidity. Anticipated
mortgage-backed securities pay downs and maturing loans also generate cashflows to meet liquidity requirements. Wholesale funding sources are also used to supply liquidity such as federal funds purchased and large denomination certificates of
deposit. The Company considers its sources of liquidity to be adequate to meet its anticipated needs.

CAPITAL
RESOURCES

Cardinal Bankshares capital position provides the necessary assurance required to support anticipated asset growth and to absorb
potential losses.

The Companys Tier I capital position was $27.8 million at March 31, 2006, or 20.01% of risk-weighted assets. Total risk-based
capital was $29.2 million or 21.05% of risk-weighted assets

Tier I capital consists primarily of common stockholders equity, while total risk-based
capital includes the allowance for loan losses. Risk weighted assets are determined by assigning various levels of risk to different categories of assets and off-balance sheet activities. To be well capitalized under current risk-based capital
standards, all banks are required to have Tier I capital of at least 4% and total capital of 8%. Based on these standards, Cardinal Bankshares is categorized as well capitalized at March 31, 2006.

In addition to the risk-based capital guidelines, banking regulatory agencies have adopted leverage capital ratio requirements. The leverage ratio  or core capital
to assets ratio  works in tandem with the risk-capital guidelines. The minimum leverage ratios range from three to five percent. At March 31, 2006, the Companys leverage capital ratio was 14.32%.

A WARNING ABOUT FORWARD-LOOKING STATEMENTS

This Form 10-Q contains
forward-looking statements. The Company may also make written forward-looking statements in periodic reports to the Securities and Exchange Commission, proxy statements, offering circulars and prospectuses, press releases and other written materials
and oral statements made by Cardinal Bankshares officers, directors or employees to third parties. Statements that are not historical facts, including statements about the Companys beliefs and expectations, are forward-looking
statements. These statements are based on beliefs and assumptions of the Companys management, and on information currently available to management. Forward-looking statements include statements preceded by, followed by or that include the
words believes, expects, estimates, anticipates, plans, or similar expressions. Forward-looking statements speak only as of the date they are made, and the Company undertakes no obligation
to update publicly any of them in light of new information or future events.

Forward-looking statements involve inherent risks and uncertainties.
Management cautions the readers that a number of important factors could cause actual results to differ materially from those contained in any forward-looking statement. Such factors include, but are not limited to, the following: competitive
pressures among depository and other financial institutions may increase significantly; changes in the interest rate environment may reduce margins; general economic or business conditions may lead to a deterioration in credit quality or a reduced
demand for credit; legislative or regulatory changes, including changes in accounting standards, may adversely affect the business in which Cardinal Bankshares is engaged; changes may occur in the securities markets; and competitors of the Company
may have greater financial resources and develop products that enable such competitors to compete more successfully than Cardinal Bankshares.

Other
factors that may cause actual results to differ from the forward-looking statements include the following: the timely development of competitive new products and services by the Company and the acceptance of such products and services by customers;
changes in consumer spending and savings habits; the effects of competitors pricing policies; the Companys success in managing the costs associated with



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the expansion of existing distribution channels and developing new ones, and in realizing increased revenues from such
distribution channels, including cross-selling initiatives; and mergers and acquisitions and their integration into the Company and managements ability to manage these other risks.

Management of Cardinal Bankshares believes these forward-looking statements are reasonable; however undue reliance should not be placed on such forward-looking statements, which are based on current expectations.

Forward-looking statements are not guarantees of performance. They involve risks, uncertainties and assumptions. The future results and stockholder values
of Cardinal Bankshares may differ materially from those expressed in forward-looking statements contained in this report. Many of the factors that will determine these results and values are beyond the Companys ability to control or predict.

Item 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

The principal goals of the Companys asset and
liability management strategy are the maintenance of adequate liquidity and the management of interest rate risk. Liquidity is the ability to convert assets to cash to fund depositors withdrawals or borrowers loans without significant
loss. Interest rate risk management seeks to balance the effects of interest rate changes on assets that earn interest or liabilities on which interest is paid, to protect the Company from wide fluctuations in its net interest income.

Management must insure that adequate funds are available at all times to meet the needs of its customers. On the asset side of the balance sheet, maturing investments,
loan payments, maturing loans, federal funds sold, and unpledged investment securities are principal sources of liquidity. On the liability side of the balance sheet, liquidity sources include core deposits, the ability to increase large
denomination certificates, federal funds lines from correspondent banks, borrowings from the Federal Reserve Bank and the Federal Home Loan Bank, as well as the ability to generate funds through the issuance of long-term debt and equity.

Interest rate risk is the effect that changes in interest rates would have on interest income and interest expense as interest-sensitive assets and interest-sensitive
liabilities either reprice or mature. Management attempts to maintain the portfolios of earning assets and interest-bearing liabilities with maturities or repricing opportunities at levels that will afford protection from erosion of net interest
margin, to the extent practical, from changes in interest rates.

The Company uses a number of tools to manage its interest rate risk, including simulating
net interest income under various scenarios, monitoring the present value change in equity under the same scenarios, and monitoring the difference or gap between rate sensitive assets and rate sensitive liabilities over various time periods.

The earnings simulation model forecasts annual net income under a variety of scenarios that incorporate changes in absolute level of interest rates,
changes in the shape of the yield curve and changes in interest rate relationships. Management evaluates the effect on net interest income from gradual changes in the Prime Rate of up to 200 basis points up or down over a 12-month period. The
current model indicates that an increase in rates of 200 basis points over the next twelve months would result in an increase in net interest income of $926 thousand, or 12.74%, while a similar decrease in rates would result in a decrease in net
interest income of $866 thousand, or 11.90%. The model also incorporates managements forecasts for balance sheet growth, noninterest income and noninterest expense. The interest rate scenarios are used for analytical purposes and do not
represent managements view of future market movements. Rather, these are intended to provide a measure of the degree of volatility interest rate movements may apply to the earnings of the Company. Modeling the sensitivity of earnings to
interest rate risk is highly dependent on numerous assumptions embedded in the simulation model. While the earnings sensitivity analysis incorporates managements best estimate of interest rate and balance sheet dynamics under various market
rate movements, the actual behavior and resulting earning impact likely will differ from projected.



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Additional qualitative information about interest rate risk is included in the Companys Annual Report on Form 10-K
for the year ended December 31, 2005. There have not been any material changes since December 31, 2005.

Item 4. CONTROLS AND PROCEDURES

As of the end of the period covered by this report, we carried out an evaluation of the
effectiveness of the design and operation of our disclosure controls and procedures, including internal controls and procedures for financial reporting. Our principal executive officer and principal financial officer supervised this evaluation and
have concluded that our disclosure controls and procedures are effective. Subsequent to this evaluation, (i) there have been no significant changes in our internal controls or in other factors that could significantly affect our disclosure
controls and procedures and (ii) we have not taken any corrective actions with regard to our disclosure controls and procedures to correct any significant deficiencies and weaknesses.

The design of any system of controls is based in part upon certain assumptions about the likelihood of future events. There can be no assurance that any design will
succeed in achieving its stated goal under every potential condition, regardless of how remote. In addition, the operation of any system of controls and procedures is dependent upon the employees responsible for executing it. While we have evaluated
the operation of our disclosure controls and procedures and found them effective, there can be no assurance that they will succeed in every instance to achieve their objective.



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|Part | II. OTHER INFORMATION
|---- | ---------------------

Item: 1 Legal proceedings

The Company was named as a defendant in a complaint filed by a former employee with the
United States Department of Labor under Section 806 of the Sarbanes-Oxley Act. The plaintiff alleged in his complaint that his termination in October, 2002 violated the Act. He is seeking reinstatement, back pay and damages. The Company
maintains that the independent members of its Board of Directors terminated the plaintiff lawfully because he refused to comply with the directives of the Audit Committee in their attempt to look into certain matters raised by the plaintiff. The
Audit Committee, after full investigation, later concluded that the matters raised by the plaintiff had no merit. The Boards decision was initially upheld by the Department of Labor. The plaintiff appealed that decision. The Department of
Labor Administrative Law Judge reversed the earlier decision in the Companys favor and entered a decision in favor of the plaintiff in January 2004. The Company appealed that decision. The Administrative Review Board of the Department of Labor
agreed to review the decision of the Administrative Law Judge in February 2004. Their decision to review suspended the decision of the Administrative Law Judge prior to any determination of damages by the Administrative Law Judge. In May 2004, the
Administrative Review Board within the Department of Labor determined that it had accepted the Companys petition for review prematurely.

Because of the uncertainty regarding the procedural handling of this case within the DOL, to preserve its ultimate ability to appeal to the Federal Courts, in June 2004, the Company filed with the United States Court of Appeals for the
Fourth Circuit a Petition for Review of the decisions of the United States Department of Labor. The appeal was determined to be premature. The parties submitted evidence to the Administrative Law Judge of damages without a further hearing in
December 2004 and January 2005. The Administrative Law Judge rendered a Supplemental Recommended Decision and Order in February 2005, which awarded damages to the plaintiff of $65 thousand, plus attorneys fees of $108 thousand, and ordered the
plaintiffs reinstatement. The Company filed a petition for review to the Administrative Review Board of the Department of Labor. The case was accepted for review by the Administrative Review Board in March 2005. The Companys management
believes it has substantial grounds for a successful appeal of the decision in the plaintiffs favor and will pursue appeals vigorously. Both sides have submitted briefs to the Administrative Review Board and are awaiting the Administrative
Review Boards decision.

On August 30, 2005, the plaintiff filed a complaint in the United States District Court for the Western
District of Virginia seeking to enforce what he claimed was a preliminary order of reinstatement issued by the Administrative Law Judge. The Court granted the Companys motion to dismiss January 14, 2006, on the grounds that there is no
preliminary order of reinstatement to enforce. The plaintiff made a motion to alter or amend the judgment of dismissal, and that motion was denied January 26, 2006. The plaintiff has not appealed the decisions of the District Court.

The plaintiff also moved the Administrative Law Judge for expedited clarification of his earlier order. Relief was denied on the grounds of lack of
jurisdiction. Then, on February 8, 2006, the plaintiff made a motion to the Administrative Review Board for expedited declaration of preliminary order of reinstatement. The Administrative Review Board determined, contrary to the United States
District Court, that the Administrative Law Judge had entered a preliminary order of reinstatement but permitted the Company to move to stay the preliminary order. The Company made that motion to stay preliminary reinstatement on April 17,
2006.



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|1A. | Risk factors
|--- | ------------

In addition to the other information set
forth in this report, you should carefully consider the factors discussed in Part I, Item 1A. Risk Factors in our Annual Report on Form 10-K for the year ended December 31, 2005, which could materially affect our business, financial
condition or future results. The risks described in our Annual Report on Form 10-K are not the only risks facing our Company. Additional risks and uncertainties not currently known to us or that we currently deem to be immaterial also may materially
adversely affect our business, financial condition and/or operating results.



|2 | Unregistered sales of equity securities and use of proceeds - None
|- | ------------------------------------------------------------------



|3 | Defaults upon senior securities - None
|- | --------------------------------------



|4 | Submission of matters to a vote of security holders - None
|- | ----------------------------------------------------------



|5 | Other information - None
|- | ------------------------



|6 | Exhibits
|- | --------



| | 31.1  | Certification of Chief Executive Officer Pursuant To Rule 13a-14(a)
| | ------ | -------------------------------------------------------------------



| | 31.2  | Certification of Principal Financial Officer Pursuant To Rule 13a-14(a)
| | ------ | -----------------------------------------------------------------------



| | 32.1  | Certification of Chief Executive Officer and Principal Financial Officer Pursuant To 18 U.S.C. Section 1350
| | ------ | -----------------------------------------------------------------------------------------------------------



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SIGNATURES

Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereto duly authorized.



|                                                                 
|-----------------------------------------------------------------
|CARDINAL BANKSHARES CORPORATION                                  
|                                                                 
|/s/ Ronald Leon Moore                                            
|Ronald Leon Moore                                                
|Chairman of the Board, President and Chief Executive Officer     
|                                                                 
|/s/ Stephanie Kent                                               
|Stephanie Kent                                                   
|Senior Vice President, Controller and Principal Financial Officer

Date: May 12, 2006



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