**EXHIBIT
        31**
 
 **Certificate
        of the Chief Executive Officer and**
 **Acting
        Chief Financial Officer**
 **Pursuant
        to 15 U.S.C. 78m(a) or 78o(d)**
 **(Section
        302 of the Sarbanes-Oxley Act of 2002)**
 
 I,
        Michael A. Grollman, certify that:
 (1) I
          have
          reviewed this Quarterly Report on Form 10-QSB of National Scientific
          Corporation;
 
 (2) Based
          on
          my knowledge, this report does not contain any untrue statement of a material
          fact or omit to state a material fact necessary to make the statements
          made, in
          light of the circumstances under which such statements were made, not misleading
          with respect to the period covered by this report;
 
 (3) Based
          on
          my knowledge, the financial statements, and other financial information
          included
          in this report, fairly present in all material respects the financial condition,
          results of operations and cash flows of the small business issuer as of,
          and
          for, the periods presented in this report;
 
 (4) The
          small business issuer’s other certifying officers and I are responsible for
          establishing and maintaining disclosure controls and procedures (as defined
          in
          Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial
          reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for
          the
          small business issuer and have:
 
 (a) Designed
          such disclosure controls and procedures, or caused such disclosure controls
          and
          procedures to be designed under our supervision, to ensure that material
          information relating to the small business issuer, including its consolidated
          subsidiaries, is made known to us by others within those entities, particularly
          during the period in which this report is being prepared;
 
 (b) Designed
          such internal control over financial reporting, or caused such internal
          control
          over financial reporting to be designed under our supervision, to provide
          reasonable assurance regarding the reliability of financial reporting and
          the
          preparation of financial statements for external purposes in accordance
          with
          generally accepted accounting principles;
 
 (c) Evaluated
          the effectiveness of the small business issuer’s disclosure controls and
          procedures and presented in this report our conclusions about the effectiveness
          of the disclosure controls and procedures, as of the end of the period
          covered
          by this report based on such evaluation; and
  (d) Disclosed
          in this report any change in the small business issuer’s internal control over
          financial reporting that occurred during the small business issuer’s most recent
          fiscal quarter that has materially affected, or is reasonably likely to
          materially affect, the small business issuer’s internal control over financial
          reporting; and
 
 (5) The
          small business issuer’s other certifying officers and I have disclosed, based on
          our most recent evaluation of internal control over financial reporting,
          to the
          small business issuer’s auditors and the audit committee of the small business
          issuer’s board of directors:
 
 (a) All
          significant deficiencies and material weaknesses in the design or operation
          of
          internal control over financial reporting which are reasonably likely to
          adversely affect the small business issuer’s ability to record, process,
          summarize and report financial information; and
 
 (b) Any
          fraud, whether or not material, that involves management or other employees
          who
          have a significant role in the small business issuer's internal control
          over
          financial reporting.
 /s/ 
Michael
                      A. GrollmanMichael
                        A. Grollman
                      Chairman,
                          Chief Executive Officer,
                        and
                          Acting Chief Financial Officer
                        May
                          22, 2006