OFFICE OF CHEMICAL SAFETY
AND POLLUTION PREVENTION 

### UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

WASHINGTON

, D.C. 20460

August 26, 2015

PC Code: 085601, 108209, 118601, 118602, 119009, 119011, 122009, 122010, 122011, 122020, 122021, 128721, 128820, 128845, 128887, 128901, 128969, 128973, 129002, 129008, 129009, 129031

MEMORANDUM DP Barcode: 427429

SUBJECT: Preliminary Ecological Risk Assessment for Registration Review of 22 Sulfonylurea Herbicides

FROM: Brian D. Kiernan, Greg Orrick, Hannah Yingling, Mary Clock-Rust, Michelle Colletti, William P. Eckel, James K. Wolf, R. David Jones, Steve Wente, and

Brian Anderson Environmental Fate and Effects Division (7507P)

TO: Margaret Hathaway, Chemical Review Manager Kevin Costello, Branch Chief RMIB2/PRD (7508P)

This memorandum transmits the draft ecological risk assessment for the Registration Review of the 22 currently registered sulfonylurea (SU) herbicides. Based on data reported in the Problem Formulations for Registration Review and evaluation of previous risk assessments, the Environmental Fate and Effects Division (EFED) has established that the only direct risks of ecological concern are to terrestrial and aquatic plants ( i.e. there are no direct risk to animals). In addition, there is risk of indirect effects to animals that are dependent upon plants for food and

shelter.

Based on the established risk profile for this class of herbicides, this document presents a refined assessment focused on risks to plants. In particular, EFED has taken advantage of the full array of vegetative vigor and seedling emergence toxicity tests available to explore the effect of spray drift droplet sizes on the distance to which risk extends for each chemical/species combination available, based on representative rates for each chemical. In addition to TerrPlant Risk Quotients, the assessment uses AgDRIFT deposition curves to express the risks to plants from spray drift as the distance to the Level of Concern (LOC = 1.0; i.e. where the Expected Environmental Concentration – EEC - equals the 25% Inhibition Concentration - IC 25 

### ), for the ten plant species tested per SU with different droplet size spectra. This information could inform in-field spray drift buffers of particular widths or other spray drift reduction options such as droplet spectrum label requirements.

### 2 

# Ecological Risk Assessment for the Registration Review of 22 Sulfonylurea Herbicides

Prepared by:

Brian D. Kiernan, Greg Orrick, Hannah Yingling, Mary Clock-Rust, Michelle Colletti, William P. Eckel, James K. Wolf, R. David Jones

Reviewed by: Melissa Panger and Kristina Garber, Sr. Advisors

Approved by: Brian Anderson, Branch Chief, Environmental Risk Branch II

Environmental Fate and Effects Division Office of Pesticide Programs U.S. Environmental Protection Agency 1200 Pennsylvania Avenue, NW Washington, D.C. 20460

August, 2015

### 3 Acknowledgements

The EFED SU risk assessment team would like to acknowledge the contributions of Chuck Peck and Kris Garber for their work in adapting the data array for this purpose, Jinny Yang for assistance in running the data array and Natalie Judkins for assistance with formatting the graph appendices.

Signatures

Brian Anderson ____________________________________

Michelle Colletti ____________________________________

William P. Eckel ____________________________________

Kristina Garber ____________________________________

R. David Jones ____________________________________

Brian D. Kiernan ____________________________________

Greg Orrick ____________________________________

Melissa Panger ____________________________________

Mary Clock-Rust ____________________________________

James K. Wolf ____________________________________

Hannah Yingling ____________________________________ 2015.08.27 13:18:23 -04'00'

2015.08.27 13:19:07

-04'00'



# JAMES WOLF Digitally signed by JAMES WOLF DN: c=US, o=U.S. Government, ou=USEPA, ou=Staff, cn=JAMES WOLF, dnQualifier=0000014028

Date: 2015.08.27 13:24:34 -04'00' MELISSA PANGER

2015.08.27 13:55:32 -04'00'

2015.08.27 13:58:04

-04'00'

2015.08.27 14:00:36 -04'00'

Digitally signed by Clock-Rust, MaryDN: cn=Clock-Rust, Mary, email=ClockRust.Mary@epa.gov

Date: 2015.08.27 14:55:43 -04'00' 

### ROBERT JONES

2015.08.27 15:29:36 -04'00'

### 4 Table of Contents

1. Executive Summary ............................................................................................................ 5

1.1. Risks to Non-Plant Taxa ......................................................................................... 5

1.2. Risks To Terrestrial Plants ...................................................................................... 5

1.3. Risks to Aquatic Plants ........................................................................................... 8

1.4. Remaining Major Uncertainties and Data Gaps ..................................................... 8

2. Introduction and Scope of Assessment ............................................................................. 10

3. Chemical Identification, Target Pests, and Mode of Action ............................................. 13

3.1. Residues of Concern ............................................................................................. 14

4. Use Characterization ......................................................................................................... 15

5. Environmental Fate Assessment ....................................................................................... 18

6. Aquatic Plant Assessment ................................................................................................. 19

6.1. Toxicity of SU Herbicides to Aquatic Plants ........................................................ 19

6.2. Exposure of SU Herbicides to Aquatic Plants ...................................................... 20

6.3. Risk Characterization for SU Herbicides to Aquatic Plants ................................. 27

7. Terrestrial Plant Risk Assessment .................................................................................... 30

7.1. Toxicity of SU Herbicides to Terrestrial Plants .................................................... 30

7.2. Exposure of SU Herbicides to Terrestrial Plants .................................................. 32

7.3. TerrPlant Analysis ................................................................................................ 32

7.4. Aggregate Spray Drift ........................................................................................... 34

7.5. Species-Specific Spray Drift ................................................................................. 41

7.6. Provisional use of Audrey III ................................................................................ 47

7.7. Potential Ecological Significance of Plant Impacts from SU Applications .......... 57

8. Incidents ................................................................................................................. ........... 58

9. Endocrine Disruptor Screening Program (EDSP) ............................................................. 63

10. Bibliography .................................................................................................................. ... 64 Appendix A. Residues of Concern .............................................................................................. . 69 Appendix B. Exposure Model Files .............................................................................................. 77 Appendix C. Environmental Fate Data and Chemical Structures of the Sulfonylureas and their Degradates .................................................................................................................... ..... 78 Appendix D. Collected IC 25 

### Values for Sulfonyl Urea Herbicides ........................................... 151 Appendix E. Distance to LOC for Vegetative Vigor Endpoints ................................................ 164 Appendix F. Distance to LOC Seedling Emergence Graphs ..................................................... 228 Appendix G. Audrey III Equation Documentation .................................................................... 292 Appendix H. 

### Spray drift regression curves using IORE. ........................................................... 298 Appendix I. Maximum Single Application Rates for Labeled Uses of SU Herbicides. ............ 301 Appendix J. Analysis of Non-Plant Toxicity Data .................................................................... 314

Attachment 1. Audrey 3 Outputs

### 5 1. Executive Summary

The Environmental Fate and Effects Division (EFED) has assessed the potential ecological risks associated with the use of 22 sulfonylurea (SU) herbicides identified in Table 3.1 of this document. Although there are differences across the chemicals with respect to use patterns, fate characteristics, and toxicological properties, an important commonality to all of the assessed SU herbicides is that they all may impact non-target plants at considerable distances from the treated sites. Also, none of them are expected to directly impact survival, growth, or reproduction of non-target animals from direct exposure resulting from labeled uses. The group was assessed together to ensure consistency in data evaluation, risk assessment assumptions, and risk management considerations.

SUs tend to be hydrophilic, do not volatilize, and do not bioaccumulate appreciably in the environment. SUs as a class show some tendency for transport away from the site of application dissolved in runoff. Persistence of SU herbicides varies considerably from several days up to approximately 8 months. SUs in general show low toxicity on an acute and chronic basis to aquatic and terrestrial animals and are toxic to sensitive plants at levels well below application

rates.

These herbicides are used on a variety of agricultural commodities and non-agricultural sites (see Section 4 of this document). They often may be applied by either ground or aerial methods at application rates that range from approximately 0.001 to 0.375 lbs a.i./Acre. Regardless of the application rate or use site, the predominant risks of concern that have been identified for each of the SU herbicides are to terrestrial and aquatic plants as summarized below.

1.1. Risks to Non-Plant Taxa

EPA’s past experience with sulfonylurea herbicidides is summarized in the Registration Review Problem Formulation for each chemical, which has been published in the individual regulatory dockets. Based on the results of previous risk assessments and a review of currently available toxicity data ( Appendix J ), as summarized in the Problem Formulations, EPA has determined that the only taxa for which risk concerns have been raised are terrestrial and aquatic plants. No animal taxa, either terrestrial or aquatic, have been determined to be at direct risk above concern

levels from the labeled use of SU herbicides. This assessment is therefore focused on a more indepth, comprehensive analysis of the risks to plants. Indirect risks to animals, as a consequence of adverse effects to plants are possible.

1.2. Risks To Terrestrial Plants

Conclusions . Results indicate that both runoff and spray drift have the potential to negatively impact terrestrial plants. Exposure to SUs may result in a decrease in the seedling emergence or vegetative vigor of plants inhabiting terrestrial or wetland areas located adjacent to a treated field. The standard measurement endpoint for terrestrial plants is the IC 25 

### , which is the concentration that results in a 25% decrement in plant height or standing biomass.

### 6 Refined risk analyses were conducted to evaluate the distance from the field where risks of concern extend due to spray drift transport. This analysis focused on spray drift transport because tools are available to quantify spray drift deposition resulting from different types of applications. However, potential effects from exposure of seedlings to run-off and spray drift were also evaluated. Risk metrics used in the refined analyses include: (1) standard RQs; (2) number of test species that may receive drift at levels sufficient to cause 25% effect at various distances (100 ft, 400 ft, or 1000 feet or greater) from a treated field; and (3) number of days where exposure close to a treated site (within approximately 100 feet) was estimated to exceed seedling emergence 25% effect levels. Chemicals that have the potential to impact a greater number of species at greater distances from treated sites are assumed to have greater potential for more severe environmental impacts.

These analyses showed that all SUs posed risk to terrestrial plants, and most SUs have the potential to impact sensitive species hundreds of feet from the edge of treated fields. Sulfometuron had the largest number of test species with a 25% or more effect level exceeded at 1000 feet or more from a treated site (See Section 7) followed by metsulfuron-methyl, chlorsulfuron, chlorimuron, and iodosulfuron-methyl. Orthosulfamuron and Bensulfuron-methyl

also had at least five exceedances of the IC 25 

### threshold at 400 feet. Five IC 25 

### exceedances was chosen since generally ten (10) species are tested, thus giving a 50% exceedance count. However, the ecological significance of effects is not related to this 50% metric; both the 50% count and the 400 foot distance are meant as aides in data interpretion.

Based on provisional use of the Audrey III model, near-field seedling emergence effects tended to persist greater for chlorimuron-ethyl, flazasulfuron, and iodosulfuron-methyl, each with 50% or more of the simulated days with exposures exceeding seedling emergence 25% effect level for the most sensitive plant species. These analyses are further described in Section 8 and are summarized in the following table.

Table 1.1. Summary of Selected Risk Metrics for SU Herbicides

Chemical Number of Species’ IC25 Exceeded (assuming very coarse to extremely coarse droplets) Veg Vig endpoints Number of Days with Near-Field Seedling Emergence Exceedances Aquatic Plant RQ

Vascular/Nonvascular 1000 feet 400 feet 100 feet Bensulfuron-methyl 0 3 3 NA <1/<1
Chlorimuron-ethyl 4 5 9 61.4 14/5.1

Chlorsulfuron 5 7 8 31 20/ <1

Flazasulfuron 1 2 3 57.4 22/ <1

Foramsulfuron 1 1 3 6.7 6.3/ <1
Halosulfuron-methyl 1 2 5 30.5 105/1.1

Imazosulfuron 0 0 0 7.5 NA
Iodosulfuron-methylNa 3 5 8 56.6 <1/<1

Mesosulfuron-methyl 0 0 4 42.3 <1/<1
Metsulfuron-methyl 5 6 10 39.6 22/ <1

Nicosulfuron 0 0 0 15.3 NA

### 7 Chemical Number of Species’ IC25 Exceeded (assuming very coarse to extremely coarse droplets) Veg Vig endpoints Number of Days with Near-Field Seedling Emergence Exceedances Aquatic Plant RQ

Vascular/Nonvascular 1000 feet 400 feet 100 feet

Orthosulfamuron 0 2 2 NA 3/ <1
Primisulfuron-methyl 0 1 4 11.1 2.5/ <1

Prosulfuron 0 0 2 14.3 1.6/ <1

Rimsulfuron 0 0 2 16.5 0.28 / <1
Sulfometuron-methyl 9 10 10 20.6 4.4/4.7

Sulfosulfuron 1 1 3 16.3 7.2/ <1
Thifensulfuron-methyl 2 4 5 13.1 1.5/ <1

Triasulfuron 1 1 7 20.7 11/ <1
Tribenuron-methyl NA <1 / <1
Trifloxysulfuron-Na 1 1 3 16 15/ <1
Triflusulfuron-methyl 0 1 2 0 1.1/ <1



### Effect of Droplet Size on Risk from Spray Drift

The degree to which spray quality affects the spatial footprint (distance from a treated field effects may occur) was evaluated using thr ee spray qualities for aerial application (M-C: medium-to-coarse, C-VC: coarse-to-very-coarse, and VC-XC: very-coarse-to-extremely-coarse), and for two boom heights (low, 20 inches, and high, 50 inches) for ground applications. These distances were then summarized overall (all SUs and species together), by individual test species (e.g., corn, cucumber, radish, etc.), and by individual SU herbicide (See Section 7 ).

Appendices E and F display the effect of the different spray qualities on the distance to exceedance of the IC25 for those plant species tested. Section 7.4 summarizes the number of

IC 25 

### values exceeded or not exceeded within or beyond 100-foot benchmark, as well as the

number of IC 25 

### s exceeded beyond 1,000 feet, as a function of spray droplet quality (M-C, C-VC, VC-XC) or boom height. The analysis demonstrate that as the spray quality changes from M-C to VC-XC, the number of IC 25 

### s exceeded for all SU-test species combinations and as a function of distance declines. Plants are divided into grasses and non-grasses to show the differential effect of SUs on these two categories. Results are summarized below for aerial and ground applications.

Aerial Applications . For aerial application, the change of spray quality from medium-to-coarse (M-C) to very-coarse-to-extremely-coarse (VC-XC) increases the number of IC 25 

### s that are not exceeded within the first 100 feet from 72 to 111. There is a complementary decrease in number

of IC 25 

### s exceeded beyond 100 feet from 133 to 95. The number of IC 25 

### s that are exceeded beyond 1,000 feet also decreases from 52 to 33. EFED believes that a change in spray quality to the coarsest quality feasible and compatible with efficacy, coupled with a modest buffer, could reduce the number of LOCs exceeded and reduce the spatial extent of potential environmental

effects.

### 8 Ground Applications . For ground application, a change from high boom to low boom did not greatly change the number of IC 25 

### s exceeded within the first 100 feet, or beyond 1,000 feet. However, this analysis assumes medium-to-coarse (M-C) spray for both boom heights, the coarsest offered in the AgDrift model. EFED believes that a change to coarser spray droplet quality, again coupled with a modest buffer, would reduce the spatial extent of potential effects for ground application as well.

1.3. Risks to Aquatic Plants

A screening-level assessment for risks to vascular and non-vascular aquatic plants was completed. At this level of analysis, the Level of Concern (RQ > 1) was exceeded for 16 SU herbicides for vascular plants, represented by duckweed (Lemna gibba ). The risk quotient (RQ), calculated as the ratio of estimated exposure (EEC) to the 50% effect on growth (IC 50 

### ) rangedfrom 105 (halosulfuron) to less than 1 (mesosulfuron-methyl, tribenuron-methyl, iodosulfuronmethyl-Na, bensulfuron-methyl, and rimsulfuron). See Section 6 of this document.

Risks to non-vascular plants (algae) were generally less than for duckweed. Three SUs (chlorimuron-ethyl, sulfometuron-methyl, and halosulfuron-methyl) exceeded the LOC of 1, and the maximum RQ was approximately five ( i.e. 5x point where the EEC equals the 50% growth inhibition endpoint). The most sensitive organism was generally the green alga Pseudokirchneriella subcapitata . See Section 6 of this document.

Degradates . For both aquatic vascular and non-vascular plants, EFED found that risk conclusions were very similar whether parent-only or parent-plus-degradates were considered. Available toxicity data for SU degradates, while not exhaustive, strongly suggest that the degradates, including those with complete sulfonylurea moieties ( i.e. , intact SU bridges), are not nearly as toxic to aquatic plants as the intact parent SU herbicides. The stressor of concern for terrestrial plants is also parent only.

1.4. Remaining Major Uncertainties and Data Gaps

Although individual chemical data gaps exist as noted in the Problem Formulations supporting this assessment, data are sufficient to characterize the potential risks of SU herbicides to plants and to conduct a refined terrestrial plant analysis. EFED is confident in the risk conclusions presented in this assessment with two exceptions : (1) much of the terrest rial plant toxicity data for tribenuron-methyl was found to be of limited use in risk assessment (although no data were requested at Problem Formulation); and (2) the aquatic vascular plant data were insufficient for use in risk assessment for imazosulfuron and nicosulfuron. However, based on the overall toxicity profile of these chemicals described in the problem formulations and previous risk assessments, risks from these chemicals are not expected to be substantially different than the range of potential risks described in this assessment for the sulfonylurea herbicides. When new data are submitted, if they prove inconsistent with that assumption, then those risks may need to be specifically revisited.

Many of the terrestrial plant datasets are incomplete regarding the availability of a statisticaly derived ‘no observed adverse effect level’ (NOAEL). In the past, a NOAEL has been the

### 9 preferred endpoint for endangered species assessments for plants. In the absence of a NOAEL, an interpolated inhibition concentration of 5% (IC 05 

### ) is used. The use of an IC 05 

### can often be considerably more conservative than a statistically-derived NOAEL, and not all of the datasets are sufficient to derive even this value. If future assessments require NOAEL values, quantitative risk estimates may not be possible in some cases.

Based on the new pollinator guidance (USEPA, 2014), additional data on pollinators will be needed to fully characterize the risk associated with SU use to all developmental stages of honeybees. Sensitivity may vary according to life-stage and length of exposure (adult vs. larval and acute vs. chronic, respectively). Therefore, there is uncertainty associated with risks to honey bees that will be evaluated if additional data on the different life stages are submitted.

### 10 2. Introduction and Scope of Assessment

Under the Federal Insecticide, Fungicide, and Roden ticide Act (FIFRA), all pe sticides distributed or sold in the United States generally must be registered by the Environmental Protection Agency (EPA). As part of determining whether a pesticide can be registered in the U.S., the Agency evaluates its safety to non-target species based on a wide range of environmental and health effects studies. In 1996, FIFRA was amended by the Food Quality Protection Act, and the Agency was mandated to implement a new program for the periodic review of pesticides, i.e

., Registration Review ( http://www.epa.gov/oppsrrd1/registration_review/ ). The Registration Review program is intended to ensure that, as the ability to assess risk evolves and as policies and practices change, all registered pesticides continue to meet the statutory standard of no unreasonable adverse effects to human health and the environment. Changes in science, public policy, and pesticide use practices occur over time. Through the Registration Review program, the Agency periodically reevaluates pesticides to make sure that as change occurs, products in the marketplace can be used safely.

The end result of the EPA pesticide registration review process ( i.e. , the FIFRA regulatory action) is an approved product label. The label is a legal document that stipulates how and where a given pesticide may be used. Product labels (also known as end-use labels) describe the formulation type ( e.g. , liquid or granular), acceptable methods of application, approved use sites, and any restrictions on how applications may be conducted. Therefore, the uses, or potential uses, described by the pesticide’s labels are considered “the action” being assessed. This assessment was prepared to support evaluation of the registration review of the class of pesticides known as sulfonylurea herbicides.

This assessment evaluates potential risks of all registered sulfonylurea (SU) herbicides to terrestrial and aquatic plants. The Office of Pesticides Programs has a long regulatory and risk assessement history with this class of herbicides and has routinely identified only potential risks to plants as being of concern in FIFRA registration decisions. Risk to non-plant taxa has been determined to be well below EPA’s levels of concern. As part of this current effort, EFED reviewed the Problem Formulations and previous risk assessments for all of the SU herbicides for potential effects to aquatic and terrestrial animals and has ruled out potential risks at theregistered application rates at or above levels of concern. The process of ruling out risk to nonplant organisms involved collecting and analyzing available registrant-submitted data for the following endpoints: avian acute oral, avian dietary, avian reproductive (chronic), mammalian acute oral, mammalian reproductive (chronic), terrestrial invertebrate acute oral or acute contact, acute freshwater invertebrates, freshwater invertebrate lifecycle, acute freshwater fish, chronic freshwater fish, acute estuarine/marine invertebrates, estuarine/marine invertebrate life cycle, acute estuarine/marine fish, and chronic estuarine/marine fish. A full suite of the collected endpoints can be found in Appendix J . These endpoints were compared to the use rates and application scenarios to determine the magnitude of risk as compared to the Agency determined

Level of Concern set out for each taxa.

### 11 An analysis of the acute and dietary toxicity endpoints for avian species show that for each of the SU herbicides, the study yielded a non-definitive greater than value well above the estimated exposure of the chemical. For the avian acute study, the LD 50 

### values were based on studies conducted using the mallard, bobwhite and passerine species; they ranged from >1744 mg/kg-bw to >4650 mg/kg-bw. The avian dietary studies were conducted using the mallard and bobwhite

and resulted in LC 50 

### s ranging from >4360 ppm to >5620 ppm. Based on these data, the SU herbicides are considered practically non-toxic to avian species. The endpoints for avian reproductive studies ranged from 28 ppm to 1280 ppm. The affected endpoint within the reproductive study varied between chemicals; some of the effects cited were hatchling weight, hatchling survival, adult male body weight, number of eggs, and 14-day weight. When the most sensitive endpoint among the SU chemicals, 28 ppm, was compared to the estimated exposure concentrations for that chemical, the Agency chronic LOC was not exceeded, thus potential risk

to birds was considered to be minimal and will not be addressed in the remainder of the

assessment.

An analysis of the acute toxicity data for mamm als showed that 17 of the SU herbicides resulted

in an LD 50 

### value of >5000 mg/kg-bw. The LD 50 

### s for the remaining 4 chemicals ranged from 546 mg/kg-bw to >3750 mg/kg-bw. All studies were conducted using rats; the results show that the SU herbicides may be considered slightly toxic to practically non-toxic to mammals. A comparison of the most sensitive endpoint to the estimated exposure concentrations of the chemicals did not yield concern based on the Agency acute LOC of 0.5 for mammals. The available mammalian reproductive studies were conducted using rats or rabbits and were reported as NOAECs and NOAELs. The available NOAECs ranged from 25 ppm to 15000 ppm and the available NOAELs ranged from 1.9 mg/kg-bw to 5000 mg/kg-bw. Again, LOCs are not

exceeded.

Toxicity data on terrestrial invertebrates was available for each of the chemicals. All but one of the studies was conducted as an acute contact study using the honeybee. The LD 50 

### s ranged from

>1.9 ȝ g/bee to >100 ȝ g/bee. Only two of the LD 50 

### s from the studies yielded definitive values;

the LD 50 

### s were equal to 12.5 ȝ g/bee and 98.2 ȝ g/bee; both of these values indicate that the SU herbicides are practically non-toxic to terrestrial invertebrates. Based on this data the potential risk to terrestrial invertebrates is considered to be minimal, pending further data requests for pollinators. Terrestrial invertebrate risk will not be further addressed in the remained of the

assessment.

The endpoints of the acute toxicity data for freshwater invertebrates ranged from >10 ppm to >1000 ppm. All of the studies, with the exception of one, were conducted using the daphnid. Additionally, all the of studies, with the excpetion of one, resulted in non-definitive, greater than endpoints; the exception resulted in an EC 50 

### = 720 ppm. Based on these study results, the SU herbicides are practically non-toxic to freshwater invertebrates on an acute basis. The chronic toxicity data for freshwater invertebrates ranged from NOAEC = 0.106 ppm to 114 ppm. The affected endpoints varied between dry weight, growth, decreased in number of young per female, and survival; in some chemicals no endpoints were affected. These values were compared to the 21-day estimated exposure concentrations and did not exceed the Agency chronic LOC for aquatic species.

### 12 An analysis of the acute toxicity studies for freshwater fish found all SU herbicides to be slightly toxic to practically nontoxic. The studies were conducted using the rainbow trout and bluegill sunfish. Nearly all of the endpoints were non-definitive values and ranged from >10 ppm to >1000 ppm; two of the chemicals yielded definitive endpoints at 115.2 ppm and 210 ppm. These values compared to the peak estimated exposure concentration, show the level of risk to freshwater fish to be well below the Agency’s acute LOC for aquatic organisms. Available reproductive toxicity tests were conducted using the fatheard minnow and the rainbow trout and NOAECs ranged from 1.5 ppm to 100 ppm. The affected endpoints varied between growth, survival and hatchling survival; some of the chemicals saw no effects. These values compared to the 60-day EEC found the risk to be below the Agency LOC of 1.0.

Toxicity data for estuarine/marine invertebrates was not available for all chemicals; the existing data was used to bridge the gap for those chemicals without available studies. The tested species for the acute toxicity studies were the Eastern oyster and mysid. Some of the LC 50 

### s exhibited non-definitive greater than values, and ranged from >38.2 ppm to >135 ppm; the definitive values ranged from 16 ppm to 107 ppm showing the SU herbicides to be slightly toxic to practically non-toxic to estuarine/marine invertebrates. These values were compared to the peak EEC concentrations and yielded values that do not exceed the Agency LOC for acute aquatic species. Estuarine/marine chronic data was available for three chemicals and ranged from 1.51 ppm to 27 ppm. When these values were compared to the 21-day EECs, the Agency LOC for chronic aquatic species was not exceeded.

Data for estuarine/marine fish was also not available for all chemicals; the studies were conducted using the sheepshead minnow. All of the acute toxicity tests resulted in an LC 50 

### that

was a non-definitive value. The LC 50 

### s ranged from >45 ppm to >980 ppm showing the SU herbicides to be slightly toxic to practically non-toxic to estuarine/marine fish. When these values are compared to the peak EECs, the resulting values are well below the Agnecy acute LOC for aquatic species. There was no toxicity data available to understand the chronic risk to estuarine/marine species. However, based on the chronic toxicity values from freshwater fish studies, it is not expected that the toxicity to estuarine/marine fish would be low enough to trigger risk and exceed the Agency chronic LOC of 1.0.

Based on the above findings, EFED has determined that the risks of concern continue to be impacts to plants. Therefore, this assessment will only describe direct risks to plants.

The degree to which endangered plant and animal species may be impacted indirectly from direct adverse effects on plants (indirect effects on food resources, shelter, or critical habitat features) will not be evaluated in this assessment, but will be conducted in the upcoming risk assessments for compliance with the Endangered Species Act (ESA). Currently efforts are underway to incorporate recommendations from the National Academy of Sciences (NAS 2013) on how to best conduct such assessments. When the methodology has been successfully piloted, EPA will revisit these chemicals regarding their potential impact on Federally-listed species.

This assessment, covering 22 currently registered SUs, relies heavily on the Registration Review Problem Formulations (PFs) written specifically for each chemical. For imazosulfuron, which is relatively recently registered, this assessment relies on the 2009 Section 3 new chemical

### 13 assessment. All of these documents can be found at Regulations.gov website 1 

### . While some data that were requested (called-in) during the problem formulation phase of Registration Review are still outstanding, those data will be incorporated into the upcoming individual chemical ESA assessments and are not expected to change any of the FIFRA conclusions from this assessment.

3. Chemical Identification, Target Pests, and Mode of Action

The mode of action of sulfonylureas (SUs) is the inhibition of amino acid synthesis in plants through inhibition of acetolactate synthase (ALS; also know as acetohydroxyacid synthase or AHAS). ALS is the first common enzyme in the biosynthesis of branch-chain amino acids (valine, leucine and isoleucine). ALS inhibition in plants adversely affects plant growth and reproduction. Although acetolactate is present in mammals, the biosynthesis of branch-chain amino acids occurs only in plants. Chlorsulfuron (PC Code 118601), possibly the most studied pesticidal SU, does not affect acetolactate forming enzymes in mammalian cells (Nakata, 1991). SUs in general are considerably less toxic to animals than plants.

SUs are generally broad spectrum herbicides, although individual SUs can be quite specific in terms of toxicity. In general, SUs are of greater toxicity to plants post-emergence in younger, vigorous growth stages with herbicidal action primarily centered on metabolically-active meristem. While most SUs have an effect on newly emerged plants (seedling emergence stage), herbicidal activity at this growth stage is less than in the somewhat older, vigorously growing plants (vegetative vigor stage).

The following 22 chemicals are included in this analysis ( Table 3.1 ), chemical structures are

included in Appendix C

.

1 http://www.regulations.gov/#!home

### 14 Table 3.1. Assessed Sulfonylureas and PC Codes

Chemical PC code
Bensulfuron-methyl 128820

Chlorimuron 128901

Chlorsulfuron 118601

Flazasulfuron 119011

Foramsulfuron 122020

Halosulfuron 128721

Imazosulfuron 118602
Iodosulfuron-methyl-sodium 122021
Mesosulfuron-methyl 122009

Metsulfuron 122010

Nicosulfuron 129008

Orthosulfamuron 108209
Primisulfuron-methyl 128973

Prosulfuron 129031

Rimsulfuron 129009
Sulfometuron-methyl 122011

Sulfosulfuron 85601

Thifensulfuron 128845

Triasulfuron 128969
Tribenuron methyl 128887
Trifloxysulfuron-sodium 119009
Triflusulfuron-methyl 129002



### 3.1. Residues of Concern

Structures for each SU and degradates are in Appendix C. The primary residues of concern for SUs are the parent chemical, and for terrestrial plants consideration is only given to the parent compound. However, in some cases degradates formed in sufficient quantities to require further exploration for aquatic organisms.

The sulfonylurea (SU) residues of concern (ROC) for aquatic plants are provided in Appendix

A. The discussion includes the rationales for the inclusion of particular degradates in the ROC, and in particular whether the ROC definition has changed since the problem formulation (PF) for registration review was written. In general, degradates forming less than 10% of the applied mass of parent SU are not considered to be of concern. In the absence of toxicity data, degradates that do not retain the SU bridge and the double ring structure of the parent compound are assumed to be less toxic to plants than the parent compound under the SU mechanism of action (USEPA 2011 c ). In the absence of toxicity data, major degradates that retain the SU structural group are generally considered likely to have similar toxicity to plants as the parent compound. If data were available that demonstrated a major degradate that retained the SU bridge and double ring structure was not of toxicological concern, then that particular degradate

### 15 was no longer considered to be of concern. However, modeling aquatic EECs with or without including degradates of potential concern indicate that including degradates in the analysis did

not affect risk conclusions.

4. Use Characterization

The uses and use patterns of the assessed SUs are generally described by the LUIS (labeled use information system) reports that were prepared and posted to the dockets during the problem formulation phase of Registration Review. The data are summarized in Appendix I . The risk managers assigned to the SUs were consulted to update the use patterns for this assessment to reflect any label changes that occurred after the LUIS reports were prepared. Table 4.1 lists the resulting lowest, average, and maximum single application rates labeled for the SUs. This assessment did not quantify potential risks from every labeled use of each SU herbicide. Instead, EFED modeled a single representative use for each chemical. Representative uses were defined as the large area uses with a high-end application rate. The maximum application rate was notnecessarily used to quantify potential risks if the maximum rate was associated with a smallareas use such as a spot treatment.

Table 6.2.1 (Section 6) lists the maximum seasonal or annual application rates of SUs that were assessed to estimate aquatic risk using a Tier I screening aquatic exposure model, GENEEC. Maximum single application rates were often the same as maximum seasonal or annual application rates. Labels for uses with single application rates less than seasonal or annual application rates generally did not provide a minimum reapplication interval as indicated in

Table 6.2.1 . Upper-bound usage rates provided by the Biological and Economic Analysis Division (BEAD) were used to estimate maximum annual application rates for registered uses without maximum annual application rates on the label. Labels should specify the maximum single and annual application rates, minimum application interval, and maximum number of applications. Where they do not, this risk assessment may underestimate risks from approved

labels.Table 4.1. SU Application Rates Used for Risk AssessmentaChemical LowestMaxApplication RateHighestMaxApplication RateRate for Modeling Average RatesAcross UsesWhere Available(supplied byBEAD)ApplicationMethodsNotesBensulfuronmethyl0.0470.0630.063 - only used onrice0.032Ground or AirLabeled only for riceChlorimuron-ethyl 0.0039 0.08 0.08 - soybean 0.004 to 0.017 Ground or Air–Chlorsulfuron0.00120.140.062 -rangeland/fallow0.007 to 0.047Ground or Air–Flazasulfuron 0.045 0.093 0.045 - Grapes 0.045 Ground only–Foramsulfuron0.00090.0520.038 - Corn0.029 to 0.032Ground onlyfor turf andground or airfor corn–Halosulfuronmethyl0.03 0.14 0.094 – corn (most usesat 0.047)0.016 to 0.077 Ground or air Most uses are ground only,but some allow aerialapplicationsImazosulfuron-0.660.3 - melons,vegetables, riceNot availableGround or airUses are ground only, exceptaerial applications areallowed on riceIodosulfuronmethyl-Na0.00013 0.0089 0.0089 - wheat 0.002 Ground only–Mesosulfuronmethyl0.00280.0130.013 - triticale andwheat0.002 to 0.011Ground or air–Metsulfuronmethyl0.00023 0.15 0.15 - ag uncultivatedareas and some forestryuses0.002 to 0.024 Ground or air Labeled for mainly non-aguses with several agriculturalusesNicosulfuron0.0120.070.066 - corn0.011 to 0.043Ground or air–Orthosulfamuron 0.066 0.066 0.066 - rice 0.061 Ground or air Labeled only for rice17Chemical LowestMaxApplication RateHighestMaxApplication RateRate for Modeling Average RatesAcross UsesWhere Available(supplied byBEAD)ApplicationMethodsNotesPrimisulfuronmethyl0.0180.0360.036 - corn0.009 to 0.022Ground or airLabeled only for bluegrassand cornProsulfuron 0.0089 0.036 0.036 – corn (most usesat 0.018)0.003 to 0.018 Ground or air No non-ag uses labeledRimsulfuron0.00780.0630.063 - most uses0.01 to 0.062Ground or airNumerous ag and non-aguses; some uses only allowground applicationsSulfometuronmethylb0.0281 0.0281 0.38 – fallow,uncultivated areasGround or air Numerous ag and non-aguses; some uses only allowground applications, butmost allow bothSulfosulfuron0.030.1250.094 - pastures0.008 to 0.07Ground or airMost uses are non-croppedareas; most uses allow onlyground applicationsThifensulfuronmethyl0.0023 0.028 0.028 - almost all uses 0.002 to 0.015 Ground or air Labeled mainly foragricultural usesTriasulfuron0.0220.0280.028 - most uses were0.0275 or 0.0280.013 to 0.019Ground or air–Tribenuron-methyl 0.0012 0.0313 0.031 - field corn,blueberries0.002 to 0.017 Ground or air Labeled mainly foragricultural usesTrifloxysulfuronNa0.0070.0360.028 – sugarcane0.006 to 0.017Ground or air–Triflusulfuronmethyl0.016 0.031 0.031 - sugar beets (allother uses at 0.016)0.008 to 0.012 Ground or air Labeled only for beets, sugarbeets, chicory, and endiveaAll rates are in units of pounds of active ingredient per acre (lbs a.i./A). “Ag” means “agricultural”; “Non-ag” means “non-agricultural”.bboth0.38and0.0281weremodeledintheterrestrialinvestigationasitisunclearwhatthemostcommonlyappliedrateis.

### Page 18 of 318 5. Environmental Fate Assessment

Sulfonylureas are typically anions. Therefore, the compounds tend to be hydrophilic, do not volatilize, and do not bioaccumulate in the environment. Water solubility limits range from 26 (trifloxysulfuron) to 3,180,000 mg/L (chlorsulfuron). The highest available whole fish bioconcentration factor (BCF) is 3.0x (tribenuron-methyl).

Based on the soil mobility data (mean values used for modeling) presented in Tables 6.2.2 through 6.2.4 , the SUs as a class may be characterized as “mobile” to “moderately mobile” on the FAO scale (USEPA, 2006). This means they will have some tendency for leaching into ground water and for transport away from the site of application dissolved in runoff.

Aerobic soil metabolism (ASM) half-lives for the SUs indicate a wide range of stability to metabolism by soil microbes, ranging from 3.6 days (shortest half-life for iodosulfuron-methyl) to 240 days (longest half-life for metsulfuron-methyl). Bensulfuron-methyl and chlorsulfuron are assumed stable to ASM in the absence of acceptable data. Iodosulfuron-methyl degrades with a half-life of 3.6-51 days to another SU, metsulfuron-methyl, that degrades slower with a half-life of 26-240 days. Thus, SU half-lives for ASM range from several days up to many months, for the same compound in some cases.

Aerobic aquatic metabolism (AAM) half-lives for the SUs indicate a wide range of stability tometabolism by aquatic microbes, similar to ASM half-lives, ranging from 9.1 days (shortest halflife for triflusulfuron-methyl) to 187 days (longest half-life for sulfometuron-methyl). Bensulfuron-methyl and chlorsulfuron are assumed stable to AAM in the absence of acceptable data. The aerobic soil and aerobic aquatic metabolism half-lives summarized in Tables 6.2.2 through 6.2.4 are conservative values prepared for model inputs as recommended by EFED guidance.

Aquatic photolysis ( Table 6.2.4 ) is not a significant degradation process for most SUs except for a few SUs whose photolysis half-lives were on the order of a few days (flazasulfuron, imazosulfuron, sulfosulfuron, and thifensulfuron-methyl).

Table 6.2.5 gives half-life values for the SUs that include the residues of concern (ROC) for plants (see Appendix A ) for use in the Total Residue (TR) exposure modeling approach. Finally, Table 6.2.6 gives details on the calculation of values in Table 6.2.4 and 6.2.5 , based on current EFED aquatic model input parameter guidance (USEPA, 2009).

Overall, the data for the SUs indicate that th eir mobility and stability to degradation are conducive to leaching into ground water and off-site transport via runoff, resulting in the

contamination of water resources.

### Page 19 of 318 6. Aquatic Plant Assessment

6.1. Toxicity of SU Herbicides to Aquatic Plants

Available data from submitted studies indicate that intact, parent SUs are significantly more toxic to tested aquatic vascular plants ( Lemna gibba ) and non-vascular plants (principally the green alga Pseudokirchneriella (Raphidocelis) subcapitata ) than even slightly modified degradates with complete sulfonylurea moieties ( i.e. , intact SU bridges). However, a complete set of degradate toxicity data for each SU was not available for each SU to confirm this observation, so RQs were calculated both on the basis of parent-only and on the basis of the residues of concern (ROC) discussed in Section 3.1. To the extent possible, toxicity data for degradates common to more than one SU were used to determine ROCs for each parent SU. As is shown below ( Table 6.2.7 ), calculation of the RQ as parent-only or as a TTR including ROCs

had little or no effect on the EECs or the risk conclusions.

As a group, the SUs are generally more toxic to vascular plants than non-vascular plants. IC 50 

### values (pesticide concentrations resulting in a 50% inhibition of growth or biomass) ranged from 0.04 ug/L to 12 ug/L. Halosulfuron and flazasulfuron were the most toxic of the group with

IC 50 

### s of 0.04 and 0.08 ug/L, respectively. However, IC 50 

### s for most SU herbicides were less than 1 ug/L with the exception of prosulfuron, thifensulfuron, tribenuron, triflusulfuron, sulfometuron, bensulfuron-methyl, and rimsulfuron, which have IC 50 

### s that range from approximately 1 to 12 ug/L. The aquatic vascular plant data were insufficient for use in risk

assessment for imazosulfuron and nicosulfuron.

Non-vasular plant IC 50 

### s ranged from approximately 0.8 ug/L (chlorimuron-ethyl) to 3000 ug/L (foramsulfuron) ( Table 6.1 ). However, IC 50 

### s were generally between 1 ug/L and 100 ug/L.

IC 50 

### s for sulfosulfuron, mesosulfuron-methyl, and foramsulfuron were all greater than 100 ug/L.

The data for imazosulfuron and nicosulfuron were not sufficient for risk assessment.

### Page 20 of 318 Table 6.1. Most sensitive endpoints for aquatic nonvascular and vascular plants.

Chemical Non-Vascular Plant IC 50 ( ȝ g/L) Vascular Plant IC 50 ( ȝ g/L) 

### Bensulfuron-methyl 7.8 8.3 Chlorimuron-ethyl 0.77 0.27

Chlorsulfuron 50 0.35

Flazasulfuron 4.1 0.076

Foramsulfuron 3300 0.56 Halosulfuron-methyl 4.1 0.042 Iodosulfuron-methyl-Na 41 0.7 Mesosulfuron-methyl 2400 0.64 Metsulfuron-methyl 31 0.36

Orthosulfamuron 80 0.7 Primisulfuron-methyl 98 0.8

Prosulfuron 10.6 1.22

Rimsulfuron 29 11.6

Rimsulfuron 0.0116 11.6 

### Sulfometuron-methyl 4.3 4.5

Sulfosulfuron 310 0.985 Thifensulfuron-methyl 2.63 1.59

Triasulfuron 35 0.19 Tribenuron-methyl 22 2 Trifloxysulfuron-Na 5.6 0.24

Imazosulfuron N/A A 

### N/A A



### Nicosulfuron N/A A 

### N/A A

A sufficient data not available



### 6.2. Exposure of SU Herbicides to Aquatic Plants

GENEEC (v2.0; Aug. 1, 2001) was used to generate estimated environmental concentrations (EECs) for representative SU uses in order to determine the extent to which the various SU herbicides pose potential risks to aquatic plants. GENEEC was used in place of scenario-based aquatic exposure models ( i.e. , Surface Water Concentration Calculator) to allow for more direct comparisons of inherent degradation, mobility, and toxicity across the SU herbicides. EECs generated by GENEEC are generally, but not always, higher than those generated by the SWCC.

Table 6.2.1 lists a collection of high-end representative use patterns that were evaluated in this assessment. The mean sorption coefficients for each SU and for residues of concern (ROC), considering the available data for ROCs, were used as exposure model inputs (see Tables 6.2.2

and 6.2.3 ). Tables 6.2.4 and 6.2.5 lists the chemical parameter model inputs for each SU and for their ROCs. All model inputs were calculated in accordance with the aquatic model Input Parameter Guidance (USEPA, 2009).

The maximum use patterns for agricultural and non-agricultural SU uses were collected, some of which were vague due to label ambiguities. Typical single application rates and number of applications per year for agricultural SU uses were also collected by BEAD for use in cases of label ambiguity. Table 6.2.1 lists a collection of high-end use pattern application rates that were evaluated in this assessment. These use patterns include maximum single application rates for representative use sites ( i.e. , major uses or most of the labeled minor uses), which are typically, but not always, the maximum agricultural application rate overall. Modeled annual application

### Page 21 of 318 rates are the maximum rates for what are thought to be representative uses, which may be less than the maximum annual application rates for other labeled uses of the given SU. Representative use sites were identified collaboratively between risk assessors and risk managers in an effort to focus the assessment on use sites that account for the largest proporation of an SU’s usage, if not the use site with the maximum labeled application rate. The intent was to support a screening approach for aquatic modeling that is most representative across the United States rather than to model a location-specific scenario.

EFED made assumptions about the number of applications per year and reapplication intervals in the absence of clear label directions, based on the typical values collected by BEAD, if available. However, labels should reflect the maximum use pattern intended to be allowed. This assessment will underestimate risks in cases where chemicals are applied more frequently or at lower intervals than assumed in the absence of clear label directions. Future assessments may make considerably more conservative assumptions if labels remain unclear or ambiguous.

Table 6.2.1. Application Rates Modeled for Sulfonylurea Representative Use Patterns

Sulfonylurea Representative Agricultural

Use Single App.

Rate (lbs a.i./A) B Reapp.

Interval

(days) Annual App. Rate (lbs a.i./A) B App.

Method A,B

Bensulfuron-methyl Rice 0.063 N/A 0.063 Aerial

Chlorimuron-ethyl Soybeans 0.080 N/A 0.080 Aerial

Chlorsulfuron Rangeland/fallow 0.062 7 C 0.12 Aerial

Flazasulfuron Grapes (no §3 ag. uses) 0.045 E N/A 0.045 E Ground

Foramsulfuron Corn 0.038 7 C 0.076 Aerial

Halosulfuron-methyl Corn 0.094 N/A 0.094 F Ground

Imazosulfuron Melons, vegetables 0.30 N/A 0.30 Ground G

Iodosulfuron-meth yl-Na Wheat 0.0089 N/A 0.0089 Ground

Mesosulfuron-methyl Wheat 0.013 N/A 0.013 Aerial

Metsulfuron-methyl Uncultivated areas 0.15 N/A 0.15 Aerial

Nicosulfuron Corn 0.066 N/A 0.066 D Aerial

Orthosulfamuron Rice 0.066 N/A 0.066 Aerial

Primisulfuron-methyl Corn 0.036 N/A 0.036 Aerial

Prosulfuron Corn, sorghum 0.036 N/A 0.036 Aerial

Rimsulfuron Rangeland 0.063 N/A 0.063 Aerial

Sulfometuron-methyl Fallo w, uncultivated areas 0.38 N/A 0.38 Aerial

Sulfosulfuron Pastures 0.094 7 C 0.13 H Aerial

Thifensulfuron-methyl Most uses 0.028 7 C 0.047 I Aerial

Triasulfuron Pastures, rangeland 0.028 7 C 0.039 H Aerial

Tribenuron-methyl Field corn, blueberries 0.031 N/A 0.031 Aerial

Trifloxysulfuron-Na Sugarcane 0.028 14 0.070 J Aerial

Triflusulfuron-methyl Sugarbeets 0.031 7 C 0.078 K Aerial
A For comparison purposes, modeled inputs for all SUs in clude a droplet size distribution of "medium to coarse" and 0-foot wide "no-spray zone" rega rdless of label directions. For SUs li mited to ground app lications, a high-boom ground sprayer with no incorporation was modeled. B This is the maximum labeled single or annual ap plication rate or application met hod for the representative agricultural use, unless otherwise specified.

### Page 22 of 318 C A 7-day reapplication interval was assu med in the absence of label directions. D An annual application rate is not specif ied on the label. One application per y ear is assumed based on usage data indicating that 96% of corn areas treated with nicosulfuron receive only one application per year. E Flazasulfuron has no §3 agricultural uses. This application rate reflects reported usage data. F An annual application rate is not specified on the label. One application per year is assumed based on usage data indicating that 87% of corn areas treated with halosulfuron-methyl receive one application per year at an average rate of 0.026 lbs a.i./acre, which is much less than the modeled rate of 0.094 lbs a.i./acre. G Aerial applications allowed on rice were not modeled because they apply to a lower application rate. H Modeled as both one and two applications at the single application rate because GENEEC cannot handle multiple applications at different rates. Because EECs nearly linearly correlate with the total applied, the EEC for one application was post-processed by multiplying the value by 1.38-1.39 (0.13/0.094 or 0.039/0.028). I Modeled as both one and two applications at the single application rate because GENEEC cannot handle multiple applications at different rates. Because EECs nearly linearly correlate with the total applied, the EEC for one application was post-processed by multiplying the value by 1.68 (0.047/0.028). J Modeled as both two and three applications at the single application rate because GENEEC cannot handle multiple applications at different rates. Because EECs nearly linearly correlate with the total applied, the EEC for two applications was post-processed by multiplying the value by 1.25 (0.070/(2x0.028)). K Modeled as both two and three applications at the si ngle application rate because GENEEC cannot handle multiple applications at different rates. Because EECs were loosely correlated with the total applied, the EEC for three applications was post-processed by multip lying the value by 0.84 (0.078/(3x0.031)).



### Table 6.2.2 lists the SU-specific mean sorption coefficients for the residues of concern. K d 

### or K F 

### was used when the coefficient of variation (CV) for the parameter was less than the CV for K OC 

### or K FOC 

### . Otherwise, K OC 

### or K FOC 

### was used. Freundlich parameters were used when available and when less than similar non-Freundlich parameters, if available.

The representative compound was the residue of concern with the lowest mean sorption coefficient if sorption coefficient data were available. Therefore, the parent compound was the representative compound for 19 of the 22 SUs for one of three reasons: 1) the mean sorption coefficient for the parent compound was less than that for the degradates of concern, 2) data were not available for degradates of concern, or 3) there were no degradates of concern.

Table 6.2.3 lists the parent compound’s mean sorption coefficients for the three sulfonylureas for which the ROC representative compound was a degradate.

Table 6.2.2. Sulfonylurea Mean Sorption Coefficients for Residues of Concern A



### Sulfonylurea Mean K d 

### or
K F (mL/g) 

### Mean K OC 

### or K FOC

(mL/ g -oc) 

### Representative Compound Source

Bensulfuron-methyl K OC 

### =315 Parent compound Acc# 73657

Chlorimuron-ethyl K OC 

### =91 Parent compound MRID 143120

Chlorsulfuron K FOC 

### =21 Parent compound MRID 42156705

Flazasulfuron K d 

### =3.2 Parent compound MRID 46930001, 49030002 (provisional)

Foramsulfuron K FOC 

### =78 Parent compound MRID 45109723

Halosulfuron-methyl K FOC 

### =109 Parent compound MRID 42139411

Imazosulfuron K OC 

### =242 Parent compound MRID 47305117

Iodosulfuron-methyl-Na K FOC 

### =21 Metsulfuron-methyl MRID 49154301 (provisional)

### Page 23 of 318 Sulfonylurea Mean K d 

### or
K F (mL/g) 

### Mean K OC 

### or K FOC

(mL/ g -oc) 

### Representative Compound Source

Mesosulfuron-methyl K FOC 

### =78 AE F154851 MRID 45386433

Metsulfuron-methyl K FOC 

### =21 Parent compound MRID 49154301 (provisional)

Nicosulfuron K OC 

### =35 Parent compound MRID 40924222

Orthosulfamuron K F 

### =6.4 Parent compound MRID 46219074, 46578971

Primisulfuron-methyl K FOC 

### =12 Parent compound MRID 41869304

Prosulfuron K F 

### =0.22 Parent compound MRID 42685257

Rimsulfuron K FOC 

### =47 Parent compound MRID 41356336

Sulfometuron-methyl K FOC 

### =63 Parent compound MRID 42789301

Sulfosulfuron K F 

### =0.29 Parent compound MRID 44295728

Thifensulfuron-methyl K FOC 

### =28 Parent compound MRID 161290

Triasulfuron K F 

### =0.34 CGA-195660 MRID 42782002

Tribenuron-methyl K FOC 

### =31 Parent compound MRID 46101501

Trifloxysulfuron-Na K F 

### =0.59 Parent compound MRID 45371825

Triflusulfuron-methyl K F 

### =0.64 Parent compound MRID 42496861

A The lowest mean sorption coefficien t inputs are bolded and in red.



### Table 6.2.3. Sulfonylurea Mean Sorption Coefficients for Parent-only Exposure Estimates A



### Sulfonylurea Mean K d 

### or
K F 

### Mean K OC 

### or K FOC 

### Representative Compound Source

Iodosulfuron-methyl-Na K FOC 

### =19 Parent compound MRID 45109015

Mesosulfuron-methyl K F 

### =1.5 Parent compound MRID 45386432

Triasulfuron K F 

### =0.92 Parent compound MRID 41656207

A These sorption coefficients were used to estimate pare nt-only exposure for the th ree SUs for which ROC mobility was represented by a that of a transformation product.



### Table 6.2.4 lists the model inputs for the parent compound-only exposure estimates. Table 6.2.5 lists the ROC model inputs (ASM, aerobic soil metabolism, and AAM, aerobic aquatic metabolism, half-lives) for the 14 SUs with degradates of concern. Half-lives for unextracted

residues are not included. Values for SUs with no ROCs were sourced from PFs and not recalculated with PestDF nor adjusted to 25°C. Water solubility and photolysis half-lives were not adjusted for ROCs because they have a minimal impact on exposure estimates. Table 6.2.6 lists the sources and calculations supporting the input values in Tables 6.2.4 and 6.2.5

.

### Page 24 of 318 Table 6.2.4. Input Values Used for Modeling Sulfonylurea Parent Compound-Only

Chemical Parameters

Sulfonylurea K d or K OC ASM Half-life (d) Water solubility (ppm) AAM Halflife (d) Photolysis Half-life (d)
Bensulfuron-methyl K OC =315 0 (stable) 120 0 0
Chlorimuron-ethyl K OC =91 31 1200 63 0

Chlorsulfuron K FOC =21 0 (stable) 3,180,000 0 0

Flazasulfuron K d =3.2 75 2,100 36 18

Foramsulfuron K FOC =78 28 3,290 39 0
Halosulfuron-methyl K FOC =109 330 1,650 20 0

Imazosulfuron K OC =242 143 429 353 3.5
Iodosulfuron-methyl-Na K FOC =19 8.0 25,000 22 334
Mesosulfuron-methyl K F =1.5 115 483 90 385
Metsulfuron-methyl K FOC =21 22 109 363 0

Nicosulfuron K OC =35 45 8,070 87 0

Orthosulfamuron K F =6.4 43 629 32 0
Primisulfuron-methyl K FOC =12 86 70 62 0

Prosulfuron K F =0.22 317 4,000 202 0

Rimsulfuron K FOC =47 47 7,300 7.3 0
Sulfometuron-methyl K FOC =63 65 244 372 0

Sulfosulfuron K F =0.29 183 1,627 46 2.5
Thifensulfuron-methyl K FOC =28 13 2,240 25 5.7

Triasulfuron K F =0.92 54 1,500 227 87
Tribenuron-methyl K FOC =31 60 2,040 72 103
Trifloxysulfuron-Na K F =0.59 200 25.7 58 423
Triflusulfuron-methyl K F =0.64 23 110 28 127



### Table 6.2.5. Input Values Used for Modeling Sulfonylurea ROC Chemical Parameters A

Sulfonylurea K d or K OC ASM Half-life (d) Water solubility (ppm) AAM Halflife (d) Photolysis Half-life (d)
Chlorimuron-ethyl K OC =91 147 1200 293 0

Foramsulfuron K FOC =78 30 3,290 82 0
Halosulfuron-methyl K FOC =109 1489 1,650 21 0

Imazosulfuron K OC =242 141 429 393 3.5
Iodosulfuron-methyl-Na K FOC =21 68 25,000 118 334
Mesosulfuron-methyl K FOC =78 131 483 203 385
Metsulfuron-methyl K FOC =21 73 109 352 0

Nicosulfuron K OC =35 216 8,070 170 0

Orthosulfamuron K F =6.4 55 629 41 0
Primisulfuron-methyl K FOC =12 86 70 184 0

Prosulfuron K F =0.22 562 4,000 336 0
Thifensulfuron-methyl K FOC =28 188 2,240 183 5.7

Triasulfuron K F =0.34 110 1,500 257 87
Triflusulfuron-methyl K F =0.64 23 110 295 127
A ROC model inputs that differ from pa rent compound-only inputs are in bold

.

### Page 25 of 318 Table 6.2.6. Sources of Input Data for Sulfonylurea Chemical Parameters for Modeling A

Sulfonylurea ASM Half-life (d) Water solubility (ppm) AAM Half-life (d) Photolysis Halflife (d)
Bensulfuron-methyl Assumed stable in the

absence of data MRID 40089309 Assumed stable in the

absence of data MRID 40089330

Chlorimuron-ethyl 90 th %-ile c.b.on mean of 6 values (MRID 145401,

49526701, 49526702) Footprint Db (http://sitem.herts.ac.u k/aeru/footprint/en/) 2x ASM t1/2 MRID 145779,

154438

Chlorsulfuron

MRID 00035275 MRID 42454104 Assumed stable in the absence of data; stable to hydrolysis MRID 42156702

Flazasulfuron Single value (25) x 3 (MRID 46220951) MRID 46220905 90 th %-ile c.b.on mean of 2 values (24, 30; MRID 46220954) MRID 46220950

Foramsulfuron 90 th %-ile c.b.on mean of 5 values (MRID 45109713, -14) MRID 45109321 90 th %-ile c.b.on mean of 2 values (MRID 45109728) MRID 45109325

Halosulfuron-methyl 90 th %-ile c.b.on mean of 2 values (MRID 42139410) MRID 43237101 Single value x 3 (MRID 45671701) MRID 42661409

Imazosulfuron 90 th %-ile c.b.on mean of 2 values (MRID 47305122, 47766801) Source not reported in

S3NC ERA 90 th %-ile c.b.on mean of 3 values (MRID 47639702, 47679105) MRID 47305120

Iodosulfuron-methylNa 90 th %-ile c.b.on mean of 10 values (MRID 45108933, -34, -35, -36) MRID 45108619,

45108620 90 th %-ile c.b.on mean of 2 values (MRID 45109121) MRID 45108624,

45108625

Mesosulfuron-methyl 90 th %-ile c.b.on mean of 9 values (MRID 45386422, -23, -24, -25) MRID 45386215 90 th %-ile c.b.on mean of 2 values (MRID 45386430) MRID 45386420

Metsulfuron-methyl 90 th %-ile c.b.on mean of 6 values (MRID 44491201, 49154304) ACC 072767 90 th %-ile c.b.on mean of 2 values (MRID 49154307) ACC 072767

Nicosulfuron 90 th %-ile c.b.on mean of 2 values (MRID 41082622, 46240901) MRID 47006001 90 th %-ile c.b.on mean of 2 values (MRID 48354304) MRID 41082620

Orthosulfamuron 90 th %-ile c.b.on mean of 4 values (MRID 49555902, -03, -04, -05) MRID 44621909 90 th %-ile c.b.on mean of 2 values (MRID 46219017) MRID 46588509

Primisulfuron-methyl 90 th %-ile c.b.on mean of 2 values (MRID 40331263, 41418613) MRID 40331203 90 th %-ile c.b.on mean of 2 values (MRID

49125201 MRID 40856508, 40856509, 41418611

Prosulfuron 90 th %-ile c.b.on mean of 2 values (MRID 42685250, -51, 43387712, -13) MRID43387710 Single value x 3 (MRID 43387718, -19) MRID 46685248, 42685249, 43387710,

43387711

Rimsulfuron 90 th %-ile c.b.on mean of 3 values (MRID 41356334, 48332003) MRID 41356301 Hydrolysis value in

absence of AAM data in PF (MRID

41356333) MRID 41931608

Sulfometuron-methyl 90 th %-ile c.b.on mean of 2 values (MRID 42091401, 43174102/245375) Source not reported in

PF 90 th %-ile c.b.on mean of 2 values (MRID 42091403, 43174103) MRID 42182401,

43174101

### Page 26 of 318 Sulfonylurea ASM Half-life (d) Water solubility (ppm) AAM Half-life (d) Photolysis Halflife (d)

Sulfosulfuron 90 th %-ile c.b.on mean of 5 values (MRID 44295731, 44295723, 44295731) Source not reported in

PF 90 th %-ile c.b.on mean of 2 values (MRID 44295726) MRID 44295721

Thifensulfuron-methyl 90 th %-ile c.b.on mean of 2 values (MRID 145154) Footprint Db (http://sitem.herts.ac.u k/aeru/footprint/en/) 90 th %-ile c.b.on mean of 2 values (MRID 48043101) MRID 00161285

Triasulfuron 90 th %-ile c.b.on mean of 5 values (MRID 40271923, -24, 49126701, -02) MRID 40271903 90 th %-ile c.b.on mean of 2 values (MRID 49126705) MRID 41668601

Tribenuron-methyl 90 th %-ile c.b.on mean of 2 values (MRID 40245522) Source not reported in

PF Single value (24) x 3 (MRID 47643005) MRID 40245520

Trifloxysulfuron-Na Single value (67) x 3 (MRID 45371810, 45371811) MRID 45371702 Single value (19) x 3 (MRID 45371814, 45371815) MRID 45371806, 45371807,

45893304
Triflusulfuron-methyl Single value (7.7) x 3 (MRID 42466860) MRID 42496805,

42496807 90 th %-ile c.b.on mean of 3 values (MRID

48564603, -04) MRID 42991424

A "90 th %-ile c.b." means "90 th percentile confidence bound".



### Table 6.2.7 lists the screening-level aquatic acute EECs for the SUs and their ROCs, if applicable. EECs for parent compounds and their ROCs were similar for each SU. EECs were generally similar across SUs with most EECs between approximately 1 ug/L and 10 ug/L. Imazasulfuron and sulfometuron-methyl EECs were considerably higher than the rest of the SUs with an EEC of approximately 12 ug/L and 20 ug/L, respectively, which is consistent with theirhigher application rates relative to the other SUs. Iodosulfuron-methyl-Na and Mesosulfuronmethyl EECs were the two lowest at 0.41 ug/L and 0.62 ug/L, respectively, which is consistent with their relatively low application rates modeled relative to the other SUs.

Table 6.2.7. SU ROC and Parent-only Aquatic Acute EECs

Sulfonylurea Representative Agricultural

Use Parent-only Acute EEC ( μ g/L) ROC Acute EEC ( μ g/L) A

Bensulfuron-methyl Rice 2.5

-- Chlorimuron-ethyl Soybeans 3.9 4.1
Chlorsulfuron Rangeland/fallow 7.0

-- Flazasulfuron Grapes (no §3 ag. uses) 1.7

-- Foramsulfuron Corn 3.5

-- Halosulfuron-methyl Corn 4.4

-- Imazosulfuron Melons, vegetables 11.8

-- Iodosulfuron-meth yl-Na Wheat 0.41 0.47
Mesosulfuron-methyl Wheat 0.62 0.67
Metsulfuron-methyl Uncultivated areas 8.0 8.4

Nicosulfuron Corn 3.6

-- Orthosulfamuron Rice 2.1

-- Primisulfuron-methyl Corn 2.0

-- Prosulfuron Corn, sorghum 2.0

--

### Page 27 of 318 Sulfonylurea Representative Agricultural

Use Parent-only Acute EEC ( μ g/L) ROC Acute EEC ( μ g/L) A

Rimsulfuron Rangeland 3.3

-- Sulfometuron-methyl Fallo w, uncultivated areas 20

-- Sulfosulfuron Pastures 7.1

-- Thifensulfuron-methyl Most uses 2.4 2.6
Triasulfuron Pastures, rangeland 2.0 2.2
Tribenuron-methyl Field corn, blueberries 1.7

-- Trifloxysulfuron-Na Sugarcane 3.7

-- Triflusulfuron-methyl Sugarbeets 3.3

-- A ROC Acute EECs were not listed when the same as Parent-only Acute EECs.



### 6.3. Risk Characterization for SU Herbicides to Aquatic Plants

The ROC and parent-only risk quotients (RQ) for the SUs are listed in Table 6.3.1 for vascular plants and in Table 6.3.2 for non-vascular plants and displayed in Figure 6.3.1 for vascular plants and in Figure 6.3.2 for non-vascular plants. There was little to no difference between RQs for ROCs and for parent compound alone across all the SUs.

Table 6.3.1. Vascular Plant Risk Quotients (Bold RQs Exceed Level of Concern, 1.0)

Chemical IC 50 (ppm) IC 50 ( ȝ g/L) Ag Use ROC

EEC ( μ g/L) ROC RQ Parent

EEC ( μ g/L) Parent RQ

Imazosulfuron N/A A N/A A Melons, vegetables 11.8 N/A A 11.8 N/A A

Nicosulfuron N/A A N/A A Corn 3.6 N/A A 3.6 N/A A

Halosulfuron-methyl 0.000042 0.042 Corn 4.4 105 4.4 105

Metsulfuron-methyl 0.00036 0. 36 Uncultivated areas 8.4 23 8 22

Flazasulfuron 0.000076 0.076 Grapes (no ag uses) 1.7 22 1.7 22

Chlorsulfuron 0.00035 0.35 Rangeland 7 20 7 20

Trifloxysulfuron-Na 0.00024 0.24 Sugarcane 3.7 15 3.7 15

Chlorimuron-ethyl 0.00027 0.27 Soybeans 4.1 15 3.9 14

Triasulfuron 0.00019 0.19 Pastures 2.2 12 2 11

Sulfosulfuron 0.000985 0.985 Pastures 7.1 7.2 7.1 7.2

Foramsulfuron 0.00056 0.56 Corn 3.5 6.3 3.5 6.3

Sulfometuron-methyl 0.0045 4.5 Fallow 20 4.4 20 4.4

Orthosulfamuron 0.0007 0.7 Rice 2.1 3 2.1 3

Primisulfuron-methyl 0.0008 0.8 Corn 2 2.5 2 2.5

Prosulfuron 0.00122 1.22 Corn, sorghum 2 1.6 2 1.6

Thifensulfuron-methyl 0.00159 1.59 Most uses 2.6 1.6 2.4 1.5

Triflusulfuron-methyl 0.00309 3.09 Sugarbeets 3.3 1.1 3.3 1.1

Mesosulfuron-methyl 0.00064 0.64 Wheat 0.67 1.0 0.62 0.97

Tribenuron-methyl 0.002 2 Field corn, blueberries 1.7 0.85 1.7 0.85

Iodosulfuron-methyl-Na 0.0007 0.7 Wheat 0.47 0.67 0.41 0.58

Bensulfuron-methyl 0.0083 8.3 Rice 2.5 0.30 2.5 0.30

### Page 28 of 318 Chemical IC 50 (ppm) IC 50 ( ȝ g/L) Ag Use ROC

EEC ( μ g/L) ROC RQ Parent

EEC ( μ g/L) Parent RQ

Rimsulfuron 0.0116 11.6 Rangeland 3.3 0.28 3.3 0.28

A N/A means acceptable toxicity data were not available to support the assessment.



### Table 6.3.2. Non-vascular Plant Risk Quotients (Bold RQs Exceed Level of Concern, 1.0)

Chemical IC 50 (ppm) IC 50 ( ȝ g/L) Ag Use ROC

EEC ( μ g/L) ROC RQ Parent

EEC ( μ g/L) Parent RQ

Imazosulfuron N/A A N/A A Melons, vegetables 11.8 N/A A 11.8 N/A A

Nicosulfuron N/A A N/A A Corn 3.6 N/A A 3.6 N/A A

Halosulfuron-methyl 0.0041 4.1 Corn 4.4 1.1 4.4 1.1

Metsulfuron-methyl 0.031 31 Uncultiv ated areas 8.4 0.27 8 0.26

Flazasulfuron 0.0041 4.1 Grapes (no ag uses) 1.7 0.41 1.7 0.41

Chlorsulfuron 0.05 50 Rangeland 7 0.14 7 0.14

Trifloxysulfuron-Na 0.0056 5.6 Sugarcane 3.7 0.66 3.7 0.66

Chlorimuron-ethyl 0.00077 0.77 Soybeans 4.1 5.3 3.9 5.1

Triasulfuron 0.035 35 Pastures 2.2 0.063 2 0.057

Sulfosulfuron 0.31 310 Pastures 7.1 0.023 7.1 0.023

Foramsulfuron 3.3 3300 Corn 3.5 0.0011 3.5 0.0011

Sulfometuron-methyl 0.0043 4.3 Fallow 20 4.7 20 4.7

Orthosulfamuron 0.08 80 Rice 2.1 0.026 2.1 0.026

Primisulfuron-methyl 0.098 98 Corn 2 0.020 2 0.02

Prosulfuron 0.0106 10.6 Corn, sorghum 2 0.19 2 0.19

Thifensulfuron-methyl >0.00263 2.63 Most uses 2.6 < 0.99 2.4 < 0.91

Triflusulfuron-methyl 0.00484 4.84 Sugarbeets 3.3 0.68 3.3 0.68

Mesosulfuron-methyl 2.4 2400 Wheat 0.67 0.00028 0.62 0.00026

Tribenuron-methyl 0.022 22 Field corn, blueberries 1.7 0.077 1.7 0.077

Iodosulfuron-methyl-Na 0.041 41 Wheat 0.47 0.011 0.41 0.010

Bensulfuron-methyl 0.0078 7.8 Rice 2.5 0.32 2.5 0.32

Rimsulfuron >0.029 29 Rangeland 3.3 0.11 3.3 0.11
A N/A means acceptable toxicity data were not available to support the assessment.

### Page 29 of 318 Figure 6.3.1. SU RQs for Vascular Plants (Level of Concern is RQ = 1.0)

Figure 6.3.2. SU RQs for Nonvascular Plants 0 20 40 60 80 100 120ImazosulfuronNicosulfuronHalosulfuronͲmethylMetsulfuronͲmethylFlazasulfuronChlorsulfuronTrifloxysulfuronͲNaChlorimuronͲethylTriasulfuronSulfosulfuronForamsulfuronSulfometuronͲmethylOrthosulfamuronPrimisulfuronͲmethylProsulfuronThifensulfuronͲ...TriflusulfuronͲmethylMesosulfuronͲmethylTribenuronͲmethylIodosulfuronͲ...BensulfuronͲmethylRimsulfuronRQ

SU 

## SU RQs for Vascular Plants

ROC RQ

Parent RQ

N/A N/A

0 1 2 3 4 5 6NicosulfuronImazosulfuronChlorimuronͲethylSulfometuronͲmethylHalosulfuronͲmethylThifensulfuronͲ...TriflusulfuronͲmethylTrifloxysulfuronͲNaFlazasulfuronBensulfuronͲmethylMetsulfuronͲmethylProsulfuronChlorsulfuronRimsulfuronTribenuronͲmethylTriasulfuronOrthosulfamuronSulfosulfuronPrimisulfuronͲmethylIodosulfuronͲ...ForamsulfuronMesosulfuronͲmethylRQ

SU 

## SU RQs for Nonvascular Plants

ROC RQ

Parent RQ

N/A N/A

### Page 30 of 318 As indicated, there are 3 SUs with screening risks of concern to both vascular and non-vascular plants (chlorimuron-ethyl, sulfometuron-methyl, and halosulfuron-methyl), 13 SUs with screening risks of concern to vascular plants (but not nonvascular plants), 4 SUs with no screening risks of concern to either vascular or nonvascular plants, and 2 SUs with insufficient toxicity data to estimate risk to aquatic plants. Risks to vascular plants from the SUs generally appear to be greater than risks to nonvascular plants based on the greater sensitivity of vascular plants relative to non-vascular plants.

The highest vascular plant RQ was for halosulfuron-methyl in large part due to its elevated toxicity relative to the other SUs. Chlorimuron-ethyl and sulfometuron-methyl had the highest RQs for nonvascular plants. Chlorimuron-ethyl is the most toxic SU to non-vascular plants whereas sulfometuron-methyl has the highest EEC across the SUs. This analysis demonstrates that all SUs except tribenuron, iodosulfuron, bensulfuron-methyl, and rimsulfuron have the potential to affect aquatic plants at representative application rates.

7. Terrestrial Plant Risk Assessment

The primary focus for SUs in this assessment is their effect on terrestrial non-target plants. As such, a great deal of analysis was conducted to evaluate and describe potential risks. Primarily, the distance off the treated site that drift deposition would result in RQs exceeding the LOC of 1.0 was considered based on the AgDRIFTv 2.0 model. Standard RQs were also calculated based on TerrPlant v1.2.2 and the range of RQs per chemical are reported.

7.1. Toxicity of SU Herbicides to Terrestrial Plants

Available IC 25 

### s were collected for this assessment and are summarized in Appendix D . The most sensitive species for each SU are presented in Table 7.1. Toxicity of SUs to terrestrial plant taxa varies considerably across chemicals in the class and sensitivity within the data set for a given chemical also varies considerably. For instance, it is common for IC 25 

### s to vary by more than 1000-fold within the tested species for any given chemical. Vegetative vigor IC 25 

### s were generally more sensitive than seedling emergence IC 25 

### s and grasses were generally less sensitive than non-grasses. Grasses are plants in the family Poaceae; typical grasses as test species are corn, wheat, oat and ryegrass. The test species were not consistent across all the chemicals; however, several species tended to be more sensitive to SUs including cabbage, carrots, oilseed rape, and radish. It is difficult to compare the toxicities of the individual chemicals across the class; however, sensitive IC 25 

### s for each chemical were generally consistent with each other relative to application rates, although imazosulfuron was consistently the least toxic of the SU

class.

Table 7.1. Summary of Most Sensitive IC 25 

### s for Seedling Emergence (SE) and Vegetative Vigore (VV)

Chemical name Species Effects endpoints VV/SE IC 25 

### (lbs a.i./A)

bensulfuron-methyl oilseed rape height SE 0.000154

### Page 31 of 318 Chemical name Species Effects endpoints VV/SE IC 25 

### (lbs a.i./A)

bensulfuron-methyl soybean biomass VV 0.000145

chlorimuron-ethyl onion height SE 0.000011

chlorimuron-ethyl oilseed rape height VV 0.000033

chlorsulfuron pea biomass SE 0.00022

chlorsulfuron oilseed rape height VV 0.0000098

chlorsulfuron sugar beet biomass VV 0.0000098

flazasulfuron cabbage biomass SE 0.00107

flazasulfuron radish height VV 0.00004

foramsulfuron lettuce biomass SE 0.0088308

foramsulfuron radish biomass VV 5.17E-05

halosulfuron-methyl lettuce height SE 9.90E-05

halosulfuron-methyl radish biomass VV 0.000057

imazosulfuron onion biomass SE 0.034

imazosulfuron radish surv VV 0.08

iodosulfuron-methyl-Na tomato height SE 3.50E-06

iodosulfuron-methyl-Na lettuce height VV 3.70E-10

mesosulfuron-methyl lettuce height SE 0.00082

mesosulfuron-methyl soybean biomass VV 0.00014

metsulfuron-methyl sugar beet biomass SE 0.000322

metsulfuron-methyl sugar beet biomass VV 0.0000887

nicosulfuron sorghum biomass SE 0.000954

nicosulfuron oilseed rape biomass VV 0.00208

orthosulfamuron radish biomass SE 0.04

orthosulfamuron carrot biomass VV 0.00012

primisulfuron-methyl cucumber height SE 0.000132

primisulfuron-methyl cucumber height VV 0.000127

prosulfuron lettuce biomass SE 0.000071

prosulfuron onion biomass VV 0.00041

rimsulfuron sorghum biomass SE 0.000164

rimsulfuron oilseed rape height VV 0.000274

sulfometuron-methyl tomato biomass SE 0.000078

sulfometuron-methyl soybean biomass VV 0.000018

sulfosulfuron cucumber biomass SE >0.001

sulfosulfuron radish biomass VV 0.00009

thifensulfuron-methyl onion biomass SE 3.47E-05

### Page 32 of 318 Chemical name Species Effects endpoints VV/SE IC 25 

### (lbs a.i./A)

thifensulfuron-methyl sugar beet biomass VV 3.02E-05

triasulfuron lettuce height SE 0.000085

triasulfuron lettuce height VV 0.0000339

tribenuron sugar beet height SE 0.0018

tribenuron sugar beet biomass VV 0.018 a



### trifloxysulfuron-Na lettuce biomass SE 0.00061

trifloxysulfuron-Na radish biomass VV 0.00001

triflusulfuron-methyl sorghum height SE >0.125

triflusulfuron-methyl oilseed rape biomass VV 0.000087

a data taken provisionally from MRID 47748203



### 7.2. Exposure of SU Herbicides to Terrestrial Plants

Standard RQs for plants from TerrPlant v1.2.2 were calculated for the most sensitive vegetative vigor endpoints for each chemical. Additionally, the spray drift fraction at 200 feet for each chemical was calculated using AgDRIFT. All endpoints were then compared to the resulting EEC to calculate drift-only RQs. The distance of 200 feet was selected as it is roughly where the drift-only fractions in TerrPlant, 1% for ground and 5% for aerial, occur based on AgDRIFT default modeling. More information on the AgDRIFT and TerrPlants models can be found at http://www.epa.gov/pesticides/science/models_pg.htm#terrestrial.

As a measure of refinement, spray drift distances to the LOC were considered for both vegetative vigor and seedling emergence. For ground spray applications, both high- and low-boom applications were considered, using the default droplet size spectrum (fine to medium/coarse) and deposition curve from the AgDRIFT 2.0 model. For aerial application, the AgDRIFT deposition curves for medium to coarse droplet sizes (model default) were considered. Additionally, coarse to very coarse and very coarse to ultra coarse droplet spectra were considered for their effect on distance from the edge of application to the LOC.

Terrestrial plant analyses used th e application rate presented in Table 6.2.1 . However, sulfometuron was also analyzed at the pasture/rangeland rate since all application methods at the forestry rate resulted in almost all plants, for both the seedling emergence and vegetative vigor endpoints, being at risk to over 1000 feet from the edge of application.

7.3. TerrPlant Analysis

Plants immediately adjacent to a treated field may be at risk from exposure to SUs through runoff and spray drift. Currently, the TerrPlant model is used to derive EECs for runoff plus a drift fraction for terrestrial and semi-aquatic plants near areas where pesticides have been applied. Runoff exposure is assessed in TerrPlant under two scenarios: sheet and channelized runoff. In the sheet runoff scenario, the treated area generating runoff is assumed to drain into an area with equal size containing seedlings, resulting in 1, 2, or 5% of the amount applied being

### Page 33 of 318deposited (based on solubility; for SUs, 5% is used). In the channelized runoff scenario, a tento-one ratio of treatment area to receiving area is used to calculate the amount being deposited onsoil with emerging or emerged seedlings. Spray drift is also a source of pesticide loading to nontarget areas and assumed fractions of 1% for ground and 5% for aerial are added to the runoff estimates. These default drift fractions are correlated to roughly 200 feet from the edge of application based on AgDRIFT default inputs. TerrPlant estimates EECs based on application rate, application method, chemical solubility in water, type of runoff (sheet vs channelized flow) and default assumptions of drift. The RQs derived from TerrPlant for the most sensitive species for each SU are provided in Table 7.3.1 . Under the current paradigm, runoff EECs are only used with seedling emergence endpoints while the more sensitive of seedling emergence or vegetative vigor are compared to the spray drift alone.

Table 7.3.1. TerrPlant RQs for the the most sensitive species for each chemical.

Chemical Name RQs

Dry Areas Semi-Aquatic Drift Only

Bensulfuron-methyl 41 225 22

Chlorimuron-ethyl 727 4000 364

Chlorsulfuron 28 156 319

Flazasulfuron 4.2 23 56

Foramsulfuron 0.43 2.4 37

Halosulfuron-methyl 95 522 82

Imazosulfuron 0.88 4.8 0.44

Iodosulfuron-methyl-Na 254 1399 1203

Mesosulfuron-methyl 1.6 8.7 4.6

Metsulfuron-methyl 46 256 85

Nicosulfuron 6.9 38 3.5

Orthosulfamuron 0.17 0.91 28

Primisulfuron-methyl 27 150 14

Prosulfuron 51 279 25

Rimsulfuron 38 211 19

Sulfometuron-methyl 487 2679 1056

Sulfometuron-methyl (R) 90 496 195

Sulfosulfuron 9.4 52 52

Thifensulfuron-methyl 81 444 46

Triasulfuron 33 181 41

Tribenuron-methyl 172 947 86

Trifloxysulfuron-Na 4.6 25 140

Triflusulfuron-methyl <0.1 0.14 18



### Although seedling emergence endpoints are generally less sensitive than vegetative vigor endpoints for SUs, the highest estimated exposures are generated from the channelized runoff scenarios in TerrPlant. Due to this, the highest RQs result in the ‘semi-aquatic’ areas as defined

### Page 34 of 318 in the TerrPlant model. While all drift-alone RQs exceed the LOC five- to 1220-fold (except for imazosulfuron), these RQs, in the case of the SUs, are derived from the vegetative vigor endpoints. The highest RQs, up to 4000, are generally in the ‘semi-aquatic’ area and derived from the seedling emergence endpoints.

Another way of looking at the data is to evaluate the range of RQs across all test species. As noted above, the spray drift defaults in TerrPlant correspond to roughly 200 feet from the edge of application, so the range of RQs at 200 feet can be informative. Figure 7.3.1 shows the spread of RQs for the vegetative vigor endpoints for exposure to spray drift alone (medium to coarsedroplets). Note that two of the highest RQs, iodosulfuron-methyl-Na at 1097 and sulfometuronmethyl at 963were removed for presentation and scale purposes.

Figure 7.3.1. The spread of vegetative vigor RQs for drift alone (aerial; medium to coarse) at 200 feet from the edge of application.

Runoff distances from the edge of the application area are difficult to quantify, especially for channelized flow, but it can be speculated that, in general, exposure from runoff attenuates with

distance.

7.4. Aggregate Spray Drift

In this section, the entirety of the data availa ble are used to demonstrate the overall effect of droplet size spectra on distances from the edge of the application area. This means that all of the 0 50 100 150 200 250 300 350 400 450 500RQ 

## Drift Only RQs for SU Herbicides

### Page 35 of 318 species in both seedling emergence and vegetative vigor for all chemicals are looked at as a whole. This aggregation includes multiple studies that include corn, soybean, etc., both within and across chemicals, though each study is only included once. Another note is that if a species counts as an exceedance at a greater distance ( e.g. 1000’), that same species is included in the count at a nearer distance ( e.g. 50’).

AgDRIFT deposition curves and droplet spectra are used to characterize RQs and to estimate the distance from an application that adverse effects to plants may be expected to occur from spray drift alone. This part of the assessment includes both seedling emergence and vegetative vigor endpoints and presents analyses for aerial and ground spray applications. The ground spray analysis uses the AgDRIFT default fine to medium/coarse droplet spectrum, but evaluates the effect of high boom versus low boom application heights on distance to the level of concern. The aerial analysis also uses AgDRIFT Tier 1 defaults, but looks at the effect of droplet size spectra on distance to the level of concern. The level of concern is 1.0 for all plant analyses ( i.e. where the EEC is equal to the IC 25 

### ). The AgDrift analysis assumes that applications are made at a wind speed less than 10 m.p.h, a boom length of 75% of the wing span, release height of no more than 10 feet above the canopy for aerial and 2 feet above the canopy for ground spray applications, and no temperature inversions are present during application. Labels that do not specify, at a minimum, these requirements may result in spray drift that is considerably greater than what is presented in this assessment, particularly due to wind speed.

Figures 7.4.1, 7.4.2 and 7.4.3 show aggregate numbers of species tested, across all SUs, that are at or exceed the LOC at a given distance from an aerial application of various droplet spectra (based on ASABE S572). Table 7.4.1 provides the same information in tabular form. Figure

7.4.1 is an application of medium to coarse droplets, Figure 7.4.2 coarse to very coarse and Figure 7.4.3 very coarse to ultra coarse.

Figure 7.4.1. Total number (y-axis) of tested species exceeding the LOC at a given distance (x-axis; in feet) from an aerial application of medium to coarse droplet size spectrum (ASABE S572) for all SUs combined. 0 50 100 150 200 250 300

>0 ш 25 ш 50 ш 100 ш 200 ш 300 ш 400 ш 500 ш 600 ш 700 ш 800 ш 900 >997

Grasses Non grasses

### Page 36 of 318Figure 7.4.2 Number of total tested species (y-xis) exceeding the LOC at a given distance (xaxis; in feet) from an aerial application of coarse to very coarse droplet size spectrum (ASABE S572).

Figure 7.4.3. Number of total tested species (y-xis) exceeding the LOC at a given distance (x-axis; in feet) from an aerial application of very coarse to ultra coarse droplet size spectrum (ASABE S572)

.

Table 7.4.1. Numbers of IC 25 

### s that equal or exceed the LOC for three droplet size spectra (ASABE S572) at specified distances.

Distance (ft) very coarse-extreme

coarse coarse-very coarse medium-coarse
Grasses Non grasses Grasses Non grasses Grasses Non grasses

>0 57 190 93 245 93 245

 25 52 172 73 212 78 219 0 50 100 150 200 250 300

>0 ш 25 ш 50 ш 100 ш 200 ш 300 ш 400 ш 500 ш 600 ш 700 ш 800 ш 900 >997

Grasses Non grasses

0 50 100 150 200 250

>0 ш 25 ш 50 ш 100 ш 200 ш 300 ш 400 ш 500 ш 600 ш 700 ш 800 ш 900 >997

Grasses Non grasses

### Page 37 of 318 Distance (ft) very coarse-extreme

coarse coarse-very coarse medium-coarse
Grasses Non grasses Grasses Non grasses Grasses Non grasses

 50 37 154 61 196 72 207

 100 30 134 43 168 55 186

 200 21 104 31 137 37 154

 300 15 87 22 114 31 140

 400 13 79 19 98 24 122

 500 11 64 15 89 22 111

 600 8 58 14 80 20 101

 700 8 53 13 79 17 94

 800 8 46 13 71 15 89

 900 7 45 11 64 15 81

>997 7 42 9 61 14 80



### As shown above, droplet size spectrum makes a large difference in the number of species at risk at distances from the edge of the application area. The coarser the droplet spectrum used in application, the shorter the distance from the application site to the LOC, where a species is considered to be at risk. For instance, the number of exceedances at 1000 feet (49) from the application for very coarse to ultra coarse droplets is roughly half that for applications of medium to coarse (94).

While the data presented are for aerial applications , the same general trends are expected to hold true for ground applications across droplet spectra. However, the difference between high boom and low boom applications does not result in as dramatic a shift ( Table7.4.2 ). Nonetheless, lower release height does decrease the number of exceedances at a given distance.

Table 7.4.2. Numbers of IC 25 

### s that are at or exceed the EEC for ground applications at two release heights (droplet spectrum fine to medium/coarse).

Low boom High Boom

Distance (ft) Grasses Non grasses Grasses Non grasses

>0 105 271 105 272

 25 30 134 37 153

 50 21 107 25 126

 100 14 80 17 96

 200 8 60 13 77

 300 8 47 8 60

 400 7 44 8 52

 500 7 39 7 46

 600 7 33 7 43

 700 7 29 7 39

 800 5 27 7 34

 900 5 25 7 31

### Page 38 of 318 Low boom High Boom

Distance (ft) Grasses Non grasses Grasses Non grasses

>997 5 24 7 28



### A closer look at the data shows the number of species with RQs that meet or exceed the LOC (RQ = 1) at 1000 feet from the edge of the application area ( Table 7.4.3 ). Also reported in the table are the species that exceed at or beyond 400 feet from the edge of the application area.

Table 

### 7 .4.3. Count of Distances to LOC Exceeding 1,000 feet or 400 feet for Aerial Application using Very Coarse to Extremely Coarse Spray Quality

Parent SU No. of

Distances to

LOC > 1,000 ft Test Species with LOC Distance >1,000 feet Other Test Species and

distance to LOC >400 feet (distance to exceedance)

Sulfometuronmethyl 9 Corn, cucumber, 

### Oilseed rape

, pea, soybean, sugarbeet, tomato, sorghum, wheat Onion (747)

Metsulfuronmethyl 5 Cucumber, onion, soybean, sugarbeet, tomato Oilseed rape (568)

Chlorsulfuron 5 

### Oilseed rape , onion, pea, soybean, sugarbeet Tomato (641) Sorghum (517)

Chlorimuron 4 

### Oilseed rape , onion, pea, sugarbeet Tomato (499)

Iodosulfuronmethyl-Na 3 onion, cabbage, lettuce Ryegrass (479) Tomato (528)

Thifensulfuron 2 

### Oilseed rape , sugarbeet Onion (790) Sorghum (487) Flazasulfuron 1 Radish Carrot (455) Halosulfuron 1 Radish Cabbage (731) Foramsulfuron, Sulfosulfuron, Trifloxysulfuron 1 Radish --

Triasulfuron 1 Lettuce -- Orthosulfamuron 0 -- Radish (455) Carrot (764) Primisulfuron 0 -- Cucumber (433)

Bensulfuronmethyl 0 -- 

### Oilseed rape (433) Soybean (626) Tomato (440)

Triflusulfuron 0 -- 

### Oilseed rape (528)

Rimsulfuron 0 -- 

### None; max. distance 359 feet (oilseed rape)

Mesosulfuronmethyl 0 -- 

### None; max. distance 149 feet (soybean)

Prosulfuron 0 -- 

### None; max. distance 140 feet (onion)

### Page 39 of 318 Nicosulfuron 0 -- 

### None: max. distance 33 feet (oilseed rape)

Imazosulfuron 0 -- 

### None; max. distance zero feet (10 species)

Tribenuron 

### Insufficient data

Another way of looking at the aggregate data is by the number of chemicals for each test species in various distance bins across chemicals and droplet spectra. Table 7.4.4 reports the number of species that are below 100 feet to the LOC, greater than 100 feet and greater than or equal to 1000 feet. Not all chemicals were tested with each species; some species were tested for one chemical (not shown).Page40of318Table 7.4.4. Number of chemicals, by species, that result in distances to the LOC (in feet), by dropet spectrum (aerialapplication).Test speciesMedCoarseCoarse-VeryVery-ExtremeMed-CoarseCoarse-VeryVery-ExtremeMed-CoarseCoarse-VeryVery-Extreme<100’ <100’ <100’>100’>100’>100’ >1000’ >1000’ >1000’Radish 1 1 2887 6 4 4Corn 14 14 15554 1 1 1Cucumber 6 8 1113119 3 2 2Oat 10 11 15651 0 0 0OilseedRape 1 1 210109 8 5 4Onion 7 10 1214119 6 6 4Pea 4 4 6664 3 3 3Ryegrass 3 8 9943 1 0 0Soybean 7 8 11141310 4 4 3SugarBeet 4 4 4555 5 5 5Tomato 7 10 111298 5 3 2Sorghum 1 1 1666 3 1 1Wheat 5 5 5222 1 1 1Cabbage 0 1 1877 2 2 1Carrot 0 0 0666 2 1 0Lettuce 2 4 6975 2 2 2TOTAL 72 90 11113311595 52 40 33

### Page 41 of 318 7.5. Species-Specific Spray Drift

While the above analysis provides illustration of the potential shifts in the risk picture that may be attained by increasing droplet sizes, the data shown are an aggregate across all species tested for 21 of the 22 SUs evaluated in this assessment. To look more closely at how different chemicals affect different species, the available terrestrial plant toxicity data for each chemical were assessed for distance to LOC for each growth stage, seedling emergence and vegetative vigor; results are presented graphically. Vegetative vigor endpoints by species and droplet size spectrum are presented in full in Appendix E . Seedling emergence endpoints by species and droplet size spectrum are presented in full in Appendix F . The labeled dots on the graphs are the LOC for each chemical, with the endpoint in parentheses ( e.g. biomass). Different droplet size spectra were applied to each species/chemical combination and the results portrayed graphically. It is important to note that the y-axis in these graphs has no meaning; the chemicals are listed in alphabetical order from top to bottom. Also, on the x-axis is distance from edge of field (EOF), and while it is labeled out to 1200 feet, the analysis was truncated at 1000 feet as discussed earlier because 1000 feet is the furthest extent predicted by Tier 1 AgDrift modeling.

Two application rates are modeled for sulfometuron methyl, one for forestry application rate (0.38 lbs ai/A) and one for the the rangeland rate (0.09 lbs ai/A; denoted on the graphs as (R)), as it is unclear what rate would be most appropriate to model. Second, all chemicals were modeled for both aerial and ground applications; however, not all uses for all chemicals allow aerial applications. Tribenuron was not included in this drift analysis due to an incomplete terrestrial plant toxicity dataset.

Although AgDRIFT modeling indicates that spray drift could potentially pose a risk hundreds of feet from the edge of application, individual application scenarios are too varied to characterize spray drift exposure simply. For instance, spray drift from application to rights-of-way passing through wooded areas could be greatly reduced through interception by the trees on either side, although the trees themselves might be damaged. Spray drift from applications in more inhabited areas could be intercepted by buildings and other man-made structures.

While it would be difficult to go into great detail here about each species/chemical combination, Figures 7.5.1 through 7.5.6 demonstrate the effect of droplet spectra on the distance to the LOC, based on the vegetative vigor endpoints. Corn was chosen for this exercise because it, along with soybean, are species tested for each chemical. Oilseed rape was selected as an additional species to help illustrate the interpretation of the graphs presented in the appendices. For plant species with sensitivities similar to corn, six SUs meet or exceed the LOC at greaterthan 200 feet from the edge of an aerial application of medium to coarse droplets: trisulfuronmethyl, flazasulfuron, metsulfuron-methyl, chlorimuron-ethyl, chlorsulfuron and both modeled rates for sulfometuron-methyl ( Figure 7.5.1 ). Four of those meet or exceed the LOC at greater than 600 feet from the edge of application. Figure 7.5.2 presents the same analysis for oilseed rape, which is generally considerably more sensitive to SUs than corn. The graph shows that the LOC is exceeded for all SUs tested at 1000 feet except nicosulfuron and orthosulfuron. However, only approximately 1⁄2 of the SUs have been tested on oilseed rape.

### Page 42 of 318 Figure 7.5.1. Distance to the LOC for each chemical for corn, medium to coarse droplets.

Red dots indicate nondefinitive values. bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)
chlorsulfuron(biomass)
flazasulfuron(biomass) foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) orthosulfamuron(height) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(biomass)
0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 43 of 318 Figure 7.5.2. Distance to the LOC for each chemical for oilseed rape, medium to coarse droplets. Red dots indicate nondefinitive values.

When the droplet size is increased to coarse to very coarse ( Figure 7.5.3 ), the distances generally decrease such that all chemicals excepting sulfometuron fall below 500 feet for corn. Distances for two additional SUs fall below 1000 feet for oilseed rape ( Figure 7.5.4 ). bensulfuron

Ͳ methyl(biomass), 1,000 chlorimuron

Ͳ ethyl(height),

1,000 chlorsulfuron(height),

1,000 metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass),

158 orthosulfamuron(biomass)

, 0

rimsulfuron(height), 1,000

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 thifensulfuron

Ͳ methyl(biomass), 1,000 triflusulfuron

Ͳ methyl(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 44 of 318 Figure 7.5.3. Distance to the LOC for each chemical for corn, coarse to very coarse droplets. bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass)

metsulfuron

Ͳ methyl(biomass)

orthosulfamuron(height)

primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(biomass)

triflusulfuron

Ͳ methyl(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 45 of 318 Figure 7.5.4. Distance to the LOC for each chemical for oilseed rape, coarse to very coarse droplets.

The distances fall further yet when the droplet size spectrum is increased to very coarse to ultra coarse ( Figure 7.5.5. ). At this spectrum, all chemicals distance to the LOC for species with sensitivity similar to corn falls to below 300 feet. The exception remains sulfometuron methyl, which demonstrates an appreciable toxicity to corn. A similar trend is seen for oilseed rape ( Figure 7.5.6 ) as well with distances reduced considerably for a larger number of SUs compared with smaller droplet spectrum, although LOCs are still exceeded for most SUs at considerable

distances from treated sites. LOCs are still exceeded at 1000 feet for 4 of the 11 SUs tested compared with 9 of 11 SUs tested at a medium to coarse droplet spectrum. bensulfuron

Ͳ methyl(biomass), 768
chlorimuron

Ͳ ethyl(height),

1,000 chlorsulfuron(height),

1,000
metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass),

103 orthosulfamuron(biomass)

, 0

rimsulfuron(height), 636

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 1,000
triflusulfuron

Ͳ methyl(biomass), 941

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 46 of 318 Figure 7.5.5. Distance to the LOC for each chemical for corn, very coarse to ultra coarse droplets. bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) orthosulfamuron(height)

primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(biomass)

triflusulfuron

Ͳ methyl(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 47 of 318 Figure 7.5.6. Distance to the LOC for each chemical for oilseed rape, very coarse to ultra coarse droplets.

7.6. Provisional use of Audrey III

The Office of Pesticide Programs is developing a model for estimating exposure to terrestrial plants called Audrey III ( Appendix G ). Audrey III is based on a new conceptual model ( Figure

7.6.1. ) and uses PRZM to estimate runoff of a treated onto a Plant Exposure Zone (PEZ) where it is combined with loading from spray drift. bensulfuron

Ͳ methyl(biomass),

433 chlorimuron

Ͳ ethyl(height), 1,000 chlorsulfuron(height)

, 1,000
metsulfuron

Ͳ methyl(height), 568 nicosulfuron(biomass),

33 orthosulfamuron(bio mass), 0 rimsulfuron(height),

359
sulfometuron

Ͳ methyl ( R ) (biomass), 942 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass),

1,000 triflusulfuron

Ͳ methyl(biomass),

528

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 48 of 318 Figure 7.6.1. Conceptual model for Audrey III.

Loading from runoff is limited by the capacity of the PEZ to retain water and the width of the PEZ is limited to the area that can reasonably be assumed to maintain distributed overland flow. For this assessment, this width was assumed to be 30 m.

The current, provisional version of Audrey III is run in a spreadsheet using the equations described in Appendices G and H. The runoff volume, and the mass of pesticide carried with the runoff, and on eroded sediment are taken from the ‘ZTS’ file which is output from PRZM. PRZM version 5.0+ is run in the Surface Water Concentration Calculator version 1.25, a shell that is used to manage input and output and run PRZM and Variable Volume Waterbody Model (VVWM). The VVWM component of SWCC is not used by Audrey III. Spray drift curves are the same as those in the AgDrift model and have been imbedded in the Audrey III spreadsheet. These curves assume that the wind was blowing at 10 mph directly towards the PEZ during application of the pesticide.

The application practices simulated for each of 20 pesticides is in Table 7.6.1 . Pesticides which only had rice uses, bensulfuron-methyl methyl and orthosulfamuron, were not simulated as overland flow of runoff would not be expected for that use. These application practices are the same as those for the aquatic simulations with GENEEC.

### Page 49 of 318 Table 7.6.1. Sulfonylurea Representative Agricultural Use Patterns Simulated with Audrey

III

Sulfonylurea Representative Agricultural

Use Sin g le App.

Rate (lbs a.i./A) Reapp.

Interval

(days) Annual App. Rate (lbs a.i./A) App.

Method

Chlorimuron-ethyl Soybeans 0.080 N/A 0.080 Aerial
Chlorsulfuron Rangeland/fallow 0.062 7 0.12 Aerial
Flazasulfuron Grapes (no §3 ag. uses) 0.045 90 0.090 Ground

Foramsulfuron Corn 0.038 7 C 0.076 Aerial
Halosulfuron-methyl Corn 0.094 N/A 0.094 Ground
Imazosulfuron Melons, vegetables 0.30 N/A 0.30 Ground

Iodosulfuron-meth yl-Na Wheat 0.0089 N/A 0.0089 Ground
Mesosulfuron-methyl Wheat 0.013 N/A 0.013 Aerial
Metsulfuron-methyl Uncultivated areas 0.15 N/A 0.15 Aerial

Nicosulfuron Corn 0.066 N/A 0.066 Aerial
Primisulfuron-methyl Corn 0.036 N/A 0.036 Aerial
Prosulfuron Corn, sorghum 0.036 N/A 0.036 Aerial
Rimsulfuron Rangeland 0.063 N/A 0.063 Aerial
Sulfometuron-methyl Fallo w, uncultivated areas 0.38 N/A 0.38 Aerial

Sulfosulfuron Pastures 0.094 7 0.13 Aerial

Thifensulfuron- methyl fallow 0.028 7 0.047 Aerial
Triasulfuron Pastures, rangeland 0.028 7 0.039 Aerial
Tribenuron-methyl Field corn, blueberries 0.031 N/A 0.031 Aerial
Trifloxysulfuron-Na Sugarcane 0.028 14 0.070 Aerial
Triflusulfuron-methyl Sugar beets 0.031 7 0.078 Aerial



### Some of the SU which allowed more than 1 application had annual maximum application rates which were not even multiples of the single application rate. This results in unequal applications for these compounds. For sulfosulfuron, the first application was made on July 1 at the full single application rate of 0.096 lb/acre, while the second application was made at 0.034 lb/acre which is the remainder of the maximum annual application rate. For the same reason, the two applications of thifensulfuron methyl and triasulfuron were made at 0.028 and 0.019 lb/acre and 0.028 and 0.011 lb/acre, respectively. Three applications of triasulfuron were 14 days apart with two and 0.031 lb/acre and the third at 0.016 to add up to the seasonal maximum of 0.78 lb/acre.

Table 7.6.2. Sulfonylurea Representative Agricultural Use Patterns Simulated with Audrey

III

Sulfonylurea Use Site Scenario Soil Weather First App

Date
Chlorimuron-ethyl Soybeans MS soybean Loring silt loam Little Rock, AR E+14

Chlorsulfuron Rangeland FL turf Adamsville sand Daytona Beach,

FL 7/1

Flazasulfuron Grapes NY grape Lordstown channery silt

loam Erie, PA E+14

### Page 50 of 318 Sulfonylurea Use Site Scenario Soil Weather First App

Date

Foramsulfuron Corn KS corn 

### Wymore silty clay loam Topeka, KS E+14

Halosulfuron-methyl Corn KS corn 

### Wymore silty clay loam Topeka, KS E+14

Imazosulfuron Melons Fl cucumber Riviera sand West Palm Beach,

FL E+21

Iodosulfuron-methyl-Na Wheat ND wheat Bearden silty clay

loam Fargo, ND E+14

Mesosulfuron-methyl Wheat ND wheat Bearden silty clay

loam Fargo, ND E+14

Metsulfuron-methyl Uncultivated areas FL cucumber Riviera sand West Palm Beach,

FL 7/1

Nicosulfuron Corn KS corn 

### Wymore silty clay loam Topeka, KS E+14

Primisulfuron-methyl Corn KS corn 

### Wymore silty clay loam Topeka, KS E+14

Prosulfuron Corn KS corn 

### Wymore silty clay loam Topeka, KS E+14

Rimsulfuron Rangeland Fl turf Adamsville sand Daytona Beach,

FL 7/1

Sulfometuron-methyl Fallow Fl cucumber Riviera sand West Palm Beach,

FL 7/1

Sulfosulfuron Pastures Fl turf Adamsville sand Daytona Beach,

FL 7/1

Thifensulfuron-methyl fallow FL cucumber Riviera sand West Palm Beach,

FL 7/1

Triasulfuron Pastures Fl turf Adamsville sand Daytona Beach,

FL 7/1

Tribenuron-methyl Field corn, KS corn 

### Wymore silty clay loam Topeka, KS H+14

Trifloxysulfuron-Na Sugarcane FL sugarcane Wabasso fine

sand West Palm Beach,

FL 9/1

Triflusulfuron-methyl Sugarbeets MN sugarbeet 

### Bearden silty clay loam Fargo, ND P+3



### E: emergence; H: after harvest; P: at plant

For each sulfonylurea and the selected use pattern a scenario was selected that is expected to produce higher exposure values than most the of the sites in that use pattern ( Table 7.6.2 ). In general, label applications of sulfonylurea herbicides to be made –“post-emergence” were made 14 days after the emergence date of the crop, unless there were other timing restrictions on the label. Applications to turf-like scenarios ( e.g. pasture, rangeland) were made on July 1 during the middle of the primary growing season in Florida where the turf scenario is located. Flazasulfuron requires a 25 ft buffer between the edge of the application and sensitive grasses and plants and the use of a medium of coarser spray. Imazosulfuron labels states that the melon must be at least 5 inches before application so application was made 21 days after emergence. Tribenuron methyl and trifloxystrobin sodium can both be applied post-harvest. As this use

### Page 51 of 318 pattern often causes the largest runoff values, this application pattern was chosen for these two active ingredients. Trisulfuron methyl can be applied to sugar beets any time after planting, so a 3 day post-planting date was chosen for the application. For triflusulfuron, application was made 3 days after planting. Planting was assumed to be 14 days before emergence. The first application of trifloxysulfuron was made on September 1 this represents a fall application after

harvest.

The chemistry input parameters used in Audrey III are listed in Table 7.6.3. The partition

coefficient and aerobic soil metabolism half-life values are the same as those used for GENEEC. Solubility, vapor pressure, and molecular weight data are from the fate data for each pesticide. Note that these three parameters are necessary for SWCC to run but they do not affect the output of Audrey III. A foliar decay half-life of 35 d and a washoff coefficient of 0.5 cm -1 

### was assumed

for all chemicals.

Table 7.6.3. Modeled Sulfonylurea ROC Chemical Parameters

Sulfonylurea K d or K OC MWT ASM Half-life (d) Solubility ( 

### mg·L -1 ) vapor pressure (torr)

Chlorimuron-ethyl K OC =91 414.83 147 1200 4.0 x 10 -12

Chlorsulfuron K FOC =21 357.77 0 3,180,000 2.3 x 10 -11

Flazasulfuron K d =3.2 407.36 75 2,100 9.98 x 10 -8

Foramsulfuron K FOC =78 452.3 30 3,290 7.5 x 10 -6
Halosulfuron-methyl K FOC =109 434.81 1489 1,650 1 x10 -7

Imazosulfuron K OC =242 412.81 141 429 2.63 x 10 -8
Iodosulfuron-methyl-Na K FOC =21 529.28 68 25,000 2.6 x 10 -9
Mesosulfuron-methyl K FOC =78 503.55 131 483 1.1 x 10 -11
Metsulfuron-methyl K FOC =21 381.4 73 109 2.5 x 10 -12

Nicosulfuron K OC =35 410.4 216 8,070 5.25 x 10 -8
Primisulfuron-methyl K FOC =12 468.34 86 70 3.8 x 10 -8

Prosulfuron K F =0.22 419.38 562 4,000 <2.6x10 -8

Rimsulfuron K FOC =47 431.4 47 7,300 1.45 x 10 -11
Sulfometuron-methyl K FOC =63 364.38 65 244 5.4 x 10 -16

Sulfosulfuron K F =0.29 470.49 183 1,627 2.29 x 10 -10

Thifensulfuron-methyl K FOC =28 387.39 188 2,240 5.6 x 10 -11

Triasulfuron K F =0.34 401.82 110 1,500 7.5 x 10 -11
Tribenuron-methyl K FOC =31 395.4 60 2,040 4.0 x 10 -10

Trifloxysulfuron-Na K F =0.59 459.4 200 25.7 9.7 x 10 -9

Triflusulfuron-methyl K F =0.64 492.43 23 110 <1 x 10 -7
A ROC model inputs that differ from pa rent compound-only inputs are in bold

.



### While Audrey III is not currently the Agency’s official tool for assessing exposure to plants, it can be used to supplement the characterization of terrestrial risk to plants that may be identified using TerrPlant. Future versions of Audrey III will address exposure in wetlands and aquatic environments. Audrey III advantages as compared to TerrPlant include a more clearly constructed conceptual model which is related to the conceptual model used for other environmental exposure assessments for pesticides, the ability to combine runoff and spray drift

### Page 52 of 318 routes of exposure, the capability to assess how risk changes with location and crop, and to see how the exposure varies with time at a given site.

The results of the Audrey III simulations are in Table 7.6.4 . Model outputs are included in Attachment 1. These results represent the combined exposure for spray drift and runoff, and eroded sediment at the edge of the PEZ farthest from the treated field. There was not sufficient toxicity data available for tribenuron, so only the 1-in-10 year peak EEC is listed. Only triflusulfuron used on sugar beets had EECs below the LOC of 1. For all other uses the RQs ranged from10.7 for foramsulfuron on corn to 9916 for chlorimuron ethyl on soybeans in Mississippi. In all cases other than triflusulfuron and imazosulfuron, the LOC was exceeded in all years in the simulation. The first year simulated was not for imazosulfuron. However, this was an artifact of the applications being made late in the year.

In some cases EECs on the PEZ exceeded the single application rate. For example, the EEC for chlorimuron was 0.12 lb/acre whereas the single application rate was 0.080 lb/acre. This is presumed to be due to the accumulation of the pesticide from multiple spray and runoff events, but suggest caution in interpreting the results of Audrey until the tool is better validated against

field results.

While there were exceedances in every year for most SUs, the duration of the exceedances varied considerably. The rightmost column in Table 7.6.4 is the fraction of the total time in the

simulation that the EEC was over the IC 25 

### for the most sensitive crop measured. Primisulfuron exceeded the LOC only 11% of the time while flazasulfuron and mesosulfuron methyl both exceeded the LOC for 80% of the time, suggesting that they have much greater potential for suppressing new plant emergence.

Table 7.6.4. Results of Audrey III simulations for estimation of risk to seedling emergence of terrestrial plants from selected uses.

Sulfonylurea Seedling Emergence EC 25 (kg/ha) 1 in 10 Year

EEC A RQ % Years

with

exceedance % Time

with

Exceedance Chlorimuron-ethyl 3.7 x 10 -5 (onion) 0.036 2929 100 61.4

Chlorsulfuron 2.47 x10 -4 (tomato) 0.063 255 100 31.0

Flazasulfuron 1.2 x 10 -3 (cabbage) 0.010 8.5 100 57.4

Foramsulfuron 9.9 x 10 -3 (lettuce) 0.025 2.54 100 6.7
Halosulfuron-methyl 1.11 x 10 -4 (lettuce) 0.036 326 100 30.5

Imazosulfuron 3.8 x 10 -2 (onion) 0.079 2.1 73 7.5
Iodosulfuron-methyl-Na 3.92 x 10 -6 (tomato) .0009 219 100 56.6
Mesosulfuron-methyl 9.2 x 10-4 (lettuce) 0.0048 5.2 100 42.3
Metsulfuron-methyl 3.61 x 10 -4 (sugar beet) 0.11 315 100 39.6

Nicosulfuron 1.07 x 10 -3 (sorghum) 0.024 22.5 100 15.3
Primisulfuron-methyl 1.48 x 10 -4 (cucumber) 0.011 72.4 100 11.1

Prosulfuron 8.0 x 10 -5 (lettuce) 0.011 138.4 100 14.3

Rimsulfuron 1.84 x 10 -4 (sugar beet) 0.017 94.1 100 16.5
Sulfometuron-methyl 8.75 x 10 -5 (tomato) 0.011 120.9 100 20.6

Sulfosulfuron 1.12 x 10 -3 (cucumber) 0.033 29.8 100 16.3
Thifensulfuron-methyl 3.89 x 10 -5 (onion) 0.013 338 100 13.1

### Page 53 of 318 Sulfonylurea Seedling Emergence EC 25 (kg/ha) 1 in 10 Year

EEC A RQ % Years

with

exceedance % Time

with

Exceedance

Triasulfuron 9.5 x 10 -5 (lettuce) 0.010 105.8 100 20.7
Tribenuron-methyl not toxicity data 0.0092 NA NA NA
Trifloxysulfuron-Na 6.8 x 10 -4 (lettuce) 0.018 26.7 100 16.0
Triflusulfuron-methyl 1.4 x 10 -1 (sorghum) 0.020 0.14 0 0



### As an example of Audrey III output, the resulting concentration profile over 30 years, or chemograph, for chlorsulfuron applied to turf in Florida is in Figure . The graph shows the chemograph for the edge of the PEZ at the treated field border (near edge) and at the far edge of the PEZ, 30 m from the field.

Figure 7.6.2. Concentration of chlorsulfuron at the near edge and far edge of the plant exposure zone as simulated on turf in Florida using the Audrey III model.

Both chemographs consist of daily values plotted for the entire 30 year simulation. Since Audrey III assumes that the pesticide in runoff and on eroded sediment is distributed uniformly over the PEZ, differences in concentration between the near edge and the far edge are due to the difference in spray drift deposition across the PEZ. Differences in the peak concentration from year to year are due to different amounts of removal of chlorsulfuron by rainfall events between the first and second applications, and, in some case, rainfall on the day of application removing from spray drift. It is interesting to note that while chlorsulfuron was simulated assuming no degradation in the soil, degradation on the foliage and removal with runoff and leaching out of 0.00 0.02 0.04 0.06 0.08 0.10 0.12 0.14

1960 1965 1970 1975 1980 1985 1990Concenttration(kg/ha)

Year 

# Chlorsulfuron on FL Turf

Concentrations Over Time in the PEZ

Near Edge

Far Edge

### Page 54 of 318 the PEZ removed most of the chlorsulfuron from the PEZ so that there was little carryover from
year to year.

Figure 7.6.3. Annual exceedance probability of chlorsulfuron applied to turf in Florida at the far edge of the PEZ as simulated by Audrey III.

The same data as in Figure are looked at Figure in a different way. In this graph, the peak concentration at the far edge of the PEZ for each year is selected for a set of 30 values, one for each year of the simulation. These 30 values are sorted from greatest to least and plotted againt their Weibull score, which is the rank divided by the total number of values plus one. The Weibull score for data processed this way in the likelihood that a particular value will be equaled or exceeded in that fraction of the years. So, for the value at 0.1, the concentration of 0.0063 kg·ha -1 

### would be expected to be equaled or exceeded in 10% of the years or it represents a onein-ten-year return frequency. This is the return frequency used for the exposure value used for point estimate aquatic risk assessment and human health drinking water assessments in calculating RQ’s and is the value used to calculate RQs in Table 7.3.1 . The level of concern, the

IC 25 

### for seedling emergence of the most sensitive plant, which is tomato for chlorsulfuron, is also plotted in Figure . This shows that not only is the level of concern exceeded at the exposure measurement endpoint of once-in-ten year, but is exceeded in all years. This means that in every year, that seedling emergence will be suppressed during a portion of the year for the most sensitive species at the far edge of the PEZ at 30 meters. From Figure 7.6.3 , we can see that seedling emergence would be suppressed 31% of the 30 year simulation, or roughly 4 months out the year. 0 0.01 0.02 0.03 0.04 0.05 0.06 0.07

0 0.2 0.4 0.6 0.8 1Concentration(kg/ha)

Annual Exceedance Probability 

# Chlorsulfuron Audrey III Ͳ Annual Exceedance Probability

Concentration (kg/ha)

Level of Concern

### Page 55 of 318 Figure 7.6.4. Annual exceedance probability of chlorsulfuron at the far edge of the PEZ (30 m) on the distribution of measured plant seedling emergence on turf in Florida as simulated by Audrey III.

Instead of looking at just the most sensitive species, it can be useful to look at how a pesticide affects the whole distribution of species Figure . This graph tell us that all species are affected at

the IC 25 

### for seedling emergence at some point in every year. We can contrast this with Figure which shows the annual exceedance probability of percent of species affected for flazasulfuron applied to grapes in New York State. In this case, in the most extreme year, or 1 year in 31, 70% of the species would be affected by the peak concentration in the year, and in all other years, 60% of the species would be affected. While this presentation can give some idea of the effects across taxa, it is important to note that this is a distribution of tested species and does not well represent the distribution of all species that are relevant to any particular environment or field

border habitat. 0 0.2 0.4 0.6 0.8

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1Concentration(kg/ha)

Annual Exceedance Probability 

# Chlorsulfuron

Audrey III Ͳ Annual Exceedance Probability
Species Affected

Fraction of Species

Affected

### Page 56 of 318 Figure 7.6.5. Annual exceedance probability of flazaulfuron on grapes in New York at the far edge of the PEZ (30 m) on the distribution of measured plant seedling emergence on turf in Florida as simulated by Audrey III. 0 0.2 0.4 0.6 0.8

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1Concentration(kg/ha)

Annual Exceedance Probability 

# Flazasulfuron Audrey III Ͳ Annual Exceedance Probability
Species Affected

Fraction of Species

Affected

### Page 57 of 318 7.7. Potential Ecological Significance of Plant Impacts from SU Applications

The use of SU herbicides, as directed on the labels, may result in unintended adverse effects on non-target terrestrial and aquatic plants. It is unclear what the extent of these effects may be, but for most of the SUs (for at least their use pattern resulting in the highest EECs), the LOC for at least one plant species is exceeded at 1000 feet from the edge of the application area, and in general, the LOCs for many species are exceeded far from the edge of application. While effects to a single species are not likely to be a cause of great concern (barring Federally-listed species), the sensitivity of a suite of species can be used to infer effects to the surrounding communities.

In general, grasses tend to be less sensitive to SUs then non-grasses, which is not unusual for herbicides, depending on the intended target species. Many SUs are used in wheat or for rangelands where they are specifically intended to produce shifts in community composition from broadleaf weeds, many of which are undesirable as forage, toward grass-dominated systems that are preferred as forage.

EPA generally uses a 25% inhibition in growth, either biomass or height, to assess potential risk to plant species. A population of plants that experience a 25% or greater inhibition in growth early in the growing season may recover, depending on the plant, but this level of effect may have lasting consequences on the affected plants.

Plants whose growth is interrupted during their active growth period may not recover. Plants may be insufficiently competitive for resources, such as sunlight or water, due to their decreased growth. Early season interruption in growth may also result in fewer absolute seed numbers or in numbers of viable seed ( i.e. reproductive effects). In communities where SU exposures occur, relatively insensitive species may outcompete sensitiv e species, leading to shifts in community composition and subsequently shifts in community function. Such changes may result in a cascade of ecological effects on higher order species and/or edaphic functionality (such as decreased interception of excess nutrients).

The plants used in guideline testing are generally crop species selected specifically for their ease of husbandry in laboratory settings. As a rule, it is best to consider each species tested as representative of a potential sensitivity in the universe of plants that may be exposed, such that sensitivity of soybean representes not only soybean, but plants with a sensitivity similar to soybean. What those species of similar sensitivity are is not usually known. Further, to what degree the species chosen for testing are representative of the range in potential plant sensitivities found in the general ecosystem is uncertain.

Fletcher et al. (1990) studied the relationship between taxa regarding their sensitivity to various herbicides. They found sensitivity to be very similar between taxa at the genus level, while sensitivity at the family level was indicative of similar toxicity about 60% of the time. Based on their breeding, crop species may exhibit less variability in response than wild type species. Therefore, it is possible that crop species will be more or less sensitive to a given herbicide than native wild type species. Tests using wild-type species may help reduce this uncertainty (Boutin and Rogers, 2000), but a critical review paper McKelvey et al. (2002) suggests that, in general,

### Page 58 of 318 crop testing may be sufficiently protective of most plants. This indicates that, based on guideline testing, current risk assessment methodology are generally protective of the universe of plants potentially exposed to herbicide application.

Another area of uncertainty is about the potential effect of SUs on plant reproduction. As described below, chlorsulfuron was alleged to result in appreciable injury to cherry crops back in the late 1980s. These allegations led quite a bit of research into its potential effect on plant reproduction. While much of the literature available indicates that indeed exposed plants exhibit reproductive effects on the studied species, dose-response studies are few. Along with open literature, a special study conducted by DuPont (MRIDs 4877690 and 48776903) exploring the effect of chorsulfuron on soybean was conducted exploring the effect of both rate and exposure timing on reproductive endpoints ( e.g. yield and seed viability). Examining all available data, EPA concluded that vegetative vigor endpoints obtained from guideline studies (850.4150) are appropriately protective of reproductive effects. However, it remains unclear whether the timing of exposure has an effect on seed production or viability. There are data that suggest exposure at an early life stage may adversely affect plant reproduction at the same rate as exposure at bloom.

A further uncertainty in the plant risk assessm ent remains, specifically potential response of woody species. While generally adverse effects to trees are noticed, and likely reported, by owners when they are affected on residential or commercial property, effects to trees may go unnoticed when those trees are adjacent to back fields or in pasture/rangeland settings. Often these trees are vital refugia for other plants and animals, and may provide essential ecosystem services like mast production, stream bank stabilization and in-stream temperature controls through shading, among others.

Not just plant species are likely to be affected; plant biodiversity provides a number of ecosystem services, including providing habitat for pollinators and beneficial insect predators. Recently, a great deal of research has been directed at the effect of plant diversity and associated insect populations (Freemark and Boutine, 1995; Isaacs et al . 2009; Mortensen et al. , 2012. Norris and Kogan, 2000; Norris and Kogan, 2005). Similar disruptions in habitat or food sources may occur for higher order animals ( e.g. birds and mammals) in areas proximal to use sites. As changes in plant communities occur due to differences in species sensitivity, subsequent loss of preferred feed or shelter for animals can be expected. In this way, animals can be affected by use of these herbicides. Affected animals might be at any trophic level, and may particularly affect organisms with obligate relationships to specific plant species.

8. Incidents

About the Incident Databases

EIIS is an Office of Pesticide Program's (OPP) database, which includes information on all ecological incidents reported to the Agency prior to 1998 by pesticide registrants and all of the "major" incidents reported by pesticide registrants to the Agency since 1998. EIIS also includes information on incident reports submitted through other sources, such as the States, regardless of whether they are "major" incidents or not. While the emphasis of EIIS is on ecological incidents occurring within the United States, reports that are occasionally received of incidents in other

### Page 59 of 318 countries are also entered. Incidents of adverse effects on lawns and other ornamentals caused by direct application of pesticide products are not entered into EIIS. (from http://www.epa.gov/pesticides/science/efed/policy_guidance/team_authors/endangered_species_ reregistration_workgroup/esa_incident_guidance.htm )

Additional incidents have been reported to the Agency in aggregated incident reports (IDS). Pesticide registrants report certain types of in cidents to the Agency as aggregate counts of incidents occurring per product per quarter. Ecological incidents reported in aggregate reports include those categorized as "minor fish and wildlife" (W-B), "minor plant" (P-B), and "other non-target" (ONT) incidents. "Other non-target" incidents include reports of adverse effects to insects and other terrestrial invertebrates. For the sulfonylureas, registrants have reported aggregate plant incidents and these are compiled in Table 9.1 below under the “IDS”

column.

Terrestrial Plant Incident Reports for the Sulfonylurea Herbicides EPA uses incident report data as a means to identify ecological effects associated with the use of specific pesticides or active ingredients and to thereby inform pesticide regulatory decisions. Incident data can vary broadly from a complaint received over the telephone to a formal report submitted by a state for inclusion in EPA’s incident databases. The presence of incidents for a pesticide may reinforce EPA’s confidence in potential exposure pathways and predicted risk to non-target organisms. On the other hand, the absence of reported incident data for a chemical does not always indicate a lack of non-target toxic effects, particularly for wildlife and plants. As of December, 2014, there were 935 terrestrial plant incident reports for the sulfonylurea herbicides from both the Ecological Incident Information System (EIIS) and EPA’s Aggregate Incident Database (IDS). These incident reports are accompanied by varying degrees of confidence in the certainty of the association with a specific chemical, application or misapplication as well as with the legality of the use of the chemical.

Primisulfuron was implicated most often in the pesticide incident reports for the sulfonylureas, with 137 reports allegedly caused by the chemical. Prosulfuron, nicosulfuron and foramsulfuron were named as the cause of 115, 112 and 103 incident reports, respectively. Also mentioned were rimsulfuron with 88 reports, sulfometuron-methyl with 82 reports, thifensulfuron and mesosulfuron-methyl both with 81 reports and metsulfuron-methyl with 75 reports. Fewer reports were logged for other sulfonylureas (See Table 8.1 below for all chemicals). Incidents were predominantly reported for damage to non-target crop plants. Non-target plant incidents reported on crops suggest that other non-target plants exposed to drift or run-off are also impacted. However, due to the economic value of non-target crops relative to other non-target plants, the Agency rarely received reports of damage to non-target plants other than to crops and high-value ornamentals. Several notable incidents are described below.

Chlorsulfuron While not in the Agency’s EIIS database, an alleged incident of chlorsulfuron drift was reported. An orchard suffered several years of reduced yield in the late 1980s in an area near wheat farms at Horse Heaven Hills (in Washington State) where herbicides were regularly used. While the reduced yields and plant damage were not noted before the use of chlorsulfuron in the area, the investigation results were inconclusive. This incident is discussed in greater detail in the

### Page 60 of 318 environmental fate and ecological risk assessment in support of the 2005 Reregistration Eligibility Decision.

Sulfometuron Sulfometuron was alleged to be the cause of a large ecological incident caused by wind-driven erosion of soil containing sulfometuron residues (EIIS Incident Report number 1011666-001). This one highly probably incident allegedly resulted from an application of OustTM herbicide (containing sulfometuron methyl) made by the Bureau of Land Management (BLM) in the fall of 2000 to approximately 22,000 acres of Idaho forest and grassland that had been severely damaged by wildfires. Investigations by the Idaho Department of Agriculture reported that following the aerial application of OustTM at a rate of 0.0625 lb ai/A, drought and windy conditions (up to 20-40 mph) caused wind erosion of dry treated soil containing sulfometuron. Thousands of acres were alleged to have been affected and crop damage was estimated to be in excess of $78 million.

Table 8.1. Terrestrial Plant Incidents for Sulfonylureas

Chemical (total number of reports across all databases) Number or Reports, Year Range and States Taxa/Crop

Bensulfuron-methyl (2) EIIS: 1 plant report

IDS: 1 incident Trees affected from rice treatment

Chlorimuron (41) EIIS: 19 plant reports IDS: 22 incident repo rts including 20 plant reports. Agricultural crops

Chlorsulfuron (34+) EIIS: 10 plant reports IDS: 24 incident reports, including 22 plant
reports +(Also, Horse Heaven Hills incide nts- 1980’s) Agricultural crops

Flazasulfuron (2) EIIS: none IDS: 2 plant reports

Foramsulfuron (103) EIIS: 70 plant reports IDS: 33 plant reports Ag crops

Halosulfuron (3) EIIS: 1 plant report IDS: 2 plant reports

Imazosulfuron None

Iodosulfuron-methyl-Na (30) EIIS: 9 plant reports, 2003-2004 IDS: 21 plant reports Corn

Mesosulfuron-methyl (81) EIIS: 41 Plant reports IDS: 40 Plant reports Agricultural areas, residential areas fence rows, rights of way

Metsulfuron (75) EIIS: 29 plant reports IDS: 46 Plant reports Agricultural areas, turf, right of ways, Fence rows, residential areas,

ornamentals

Nicosulfuron (112) EIIS: 42 Plant reports IDS: 70 plant reports Agricultural crops

Orthosulfamuron (0) None

Primisulfuron-methyl (137) EIIS: 68 Plant reports IDS: 69 Plant reports Agricultural areas

Prosulfuron (115) EIIS: 78 plant reports IDS: 37 plant reports Agricultural areas

### Page 61 of 318 Wildlife incidents have also been reported for some of the SUs ( Table 8.2 ); however, evaluation of the incident reports together with the toxicity profile of these chemicals suggest SUs were not the primary cause of these incidents. This is consistent with the established toxicity and risk profiles of the SU chemicals. However, it is possible that aquatic animals could be impacted if SUs contaminate aquatic environments at sufficient levels to kill aquatic plants, resulting in decay and reslting lower dissolved oxygen that are too low for fish survival. For example,

incident I 008768-007 

### implicated chlorimuron along with two other herbicides in a fish kill. If chlorimuron contributed to this fish kill, it is un likely to have been caused by direct effects to fish based on the avaialable fish toxicity data. However, chlorimuron is toxic to aquatic plants; therefore, indirect effects to fish could have occurred.

Table 8.2. Non-Plant Incidents Listed in EIIS

Chemical Incident

Number Species Other Factors Contributing to Incident

Chlorimuron-ethyl I007334-001 Unknown bird Multiple herbicides were sprayed approximately 1⁄2 mile from the site of the incident. Paraquat and metribuzin were also included in the incident, which are substantiall ymore toxic to birds than chlorimuronethyl. Given the proximity of the incident to t h site of application, the low toxicity of chlorimuron-ethyl to birds, and the presence o f more toxic chemicals included in the incident, chlorimuron-ethyl is not likely the cause of bir d deaths reported in this incident.

Chlorimuron-ethyl I008768-007 Bluegill Three herbicides were implicated in the incide n including chlorimuron-ethyl, metribuzin, and paraquat dichloride. The herbicides were liste d as a possible cause of the incident. Paraquat is considerably more toxic to fish than is chlorimuron-ethyl. However, it is also possibl e that effects to bluegill were caused by indirect Rimsulfuron (88) EIIS: 43 Plant reports IDS: 45 plant reports

Sulfometuron-methyl (82) EIIS: 41 plant reports IDS: 41 plant reports Agricultural crops, including beets, forests, industrial sites, right of ways

Sulfosulfuron (0) None

Thifensulfuron (81) EIIS: 26 plant reports IDS: 55 plant reports

Triasulfuron (3) EIIS: 1 plant report IDS: 2 plant report

Tribenuron methyl (24) EIIS: 9 plant reports IDS: 15 plant reports Agricultural crops

Trifloxysulfuron-Na (3) EIIS: 2 plant reports IDS: 1 plant report Agricultural crops

Triflusulfuron (0) None

### Page 62 of 318 Chemical Incident

Number Species Other Factors Contributing to Incident

effects resulting in impacts to aquatic plants from exposure to the combination of herbicide s

Metsulfuron-methyl I000022-001 Unknown bird Diuron was listed as probable cause of incide n

Metsulfuron-methyl I005925-008 Unknown fish Metsulfuron was listed as "not likely" to have

caused the incident

Metsulfuron-methyl I000022-001 Carolina Chickadee, unknown fish, bluebirds Diuron was listed as the probably cause of the

incident

Metsulfuron-methyl I022068-001 Unknown animal Metsulfuron-methyl, dicamba dimethylamine salt, and 2,4-D were included in the incident report. Very few details were available to

determine the likelihood that metsulfuronmethyl was the cause of the incident to animal s

Sulfometuron I021587-003 Honey bee Glyphosate and sulfometuron were listed as possibly causing the incident. Bees were foun d twitching or dead in front of 3 hives within 3 days of spraying.

Sulfometuron I000903-003 Deer and unknown fish Implication that there has been a long term decrease in available forage due to herbicide spraying



### 9. Federally Threatened and Endangered (Listed) Species Concerns

In November 2013, the EPA, along with the U.S. Fish & Wildlife Service (USFWS), the National Marine Fisheries Service (NMFS) (colle ctively, the Services), and the U.S. Department of Agriculture (USDA) released a summary of their joint Interim Approaches for assessing risks to listed species from pesticides. The Interim Approaches were developed jointly by the agencies in response to the National Academy of Sciences’ (NAS) recommendations and reflect a common approach to risk assessment shared by the agencies as a way of addressing scientific

differences between the EPA and the Services. The NAS report outlines recommendations on specific scientific and technical issues related to the development of pesticide risk assessments that EPA and the Services must conduct in connection with their obligations under the Endangered Species Act (ESA) and FIFRA.

The joint Interim Approaches were released prior to a stakeholder workshop held on November 15, 2013. In addition, the EPA presented the joint Interim Approaches at the December 2013 Pesticide Program Dialogue Committee (PPDC) and State-FIFRA Issues Research and Evaluation Group (SFIREG) meetings, and held a stakeholder workshop in April 2014, allowing additional opportunities for stakeholders to comment on the Interim Approaches. As part of a phased, iterative process for developing the Interim Approaches, the agencies will also consider public comments on the Interim Approaches in connection with the development of upcoming Registration Review decisions. The details of the joint Interim Approaches are contained in the

### Page 63 of 318 white paper “Interim Approaches for National-Level Pesticide Endangered Species Act Assessments Based on the Recommendations of the National Academy of Sciences April 2013 Report,” dated November 1, 2013.

Given that the agencies are continuing to develop and work toward implementation of the Interim Approaches to assess the potential risks of pesticides to listed species and their designated critical habitat, this preliminary risk assessment for acifluorfen does not contain a complete ESA analysis that includes effects determinations for specific listed species or designated critical habitat. Although EPA has not yet completed effects determinations for specific species or habitats, based on this preliminary assessment EPA considers that an assessment will need to be conducted for terrestrial and aquatic plants and for species dependant on them. This screening level assessment will allow EPA to focus its future evaluations on the types of species where the potential for effects exists once the scientific methods being developed by the agencies have been fully vetted. Once the agencies have fully developed and implemented the scientific methods necessary to complete risk assessments for endangered and threatened (listed) species and their designated critical habitats, these methods will be applied to subsequent analyses for acifluorfen as part of completing this registration review.

10 Endocrine Disruptor Screening Program (EDSP)

The SUs were not included in the first group of 67 chemicals issued an order to conduct Tier 1 EDSP testing. For additional information on the EDSP, visit http://www.epa.gov/endo/

.

### Page 64 of 318 8. Bibliography

Boutin, C. and C.A. Rogers. 2000. Patterns of sensitivity of plant species to various herbicides—an analysis with two databases. Ecotoxicology, 9, 255-271.

Fletcher, J.S., F.L. Johnson, J.C. McFarlane. 1990. Influence of greenhouse versus field testing and taxonomic differences on plant sensitivity to chemical treatment. Environ. Toxicol. Chem. 9,

769-776



### Freemark, K., and C. Boutin. 1995. Impacts of agricultural herbicide use on terrestrialwildlife in temperate landscapes – a review with special reference to North-America. Agric. Ecosyst. Environ. 52, 67–91.

Isaacs, R., Tuell, J., Fiedler, A., Gardiner, M., Landis, D., 2009. Maximizing arthropod-mediated ecosystem services in agricultural landscapes: the role of native plants. Front. Ecol. Environ. 7, 196–203.

Mohammad, M., T. Kishimoto, K. Itoh, K. Suyama, and H. Yamamoto. 2005. Comparative Sensitivity of Pseudokirchnetiella subcapitata vs. Lemna sp. to Eight Sulfonylurea

Herbicides. ECOTOX Reference Number 104861. Bull. Environ. Contam. Toxicol.

75 (5): 866-872.

Mortensen, D.A., Egan, J.F., Maxwell, B.D., Ryan, M.R., Smith, R.G., 2012. Navigatinga critical juncture for sustainable weed management. Bioscience 62, 75–85.Norris, R.F., Kogan, M., 2000. Interactions between weeds, arthropod pests, and theirnatural enemies in managed ecosystems. Weed Sci. 48, 94–158.

Nakata, M. 1991. The mode of action of chlorsulfuron in culture cells of tobacco and hamster. J.

Pest. Sci. 16:583-590

Norris, R.F., Kogan, M., 2000. Interactions between weeds, arthropod pests, and their natural enemies in managed ecosystems. Weed Sci. 48, 94–158.

Norris, R.F., Kogan, M., 2005. Ecology of interactions between weeds and arthropods.Annu. Rev. Entomol. 50, 479–503.

U.S. Environmental Protection Agency (USEPA). 2003. Doherty, M.A., E. Budd, and A. Levy. Trifloxysulfuron-sodium: Metabolism Assessment Review Committee Report. DP barcode 293085. Office of Prevention, Pesticides, and Toxic Substances, Health Effects Division. Internal memorandum. Aug. 25, 2003.

USEPA. 2004 a . Dodd, N. and S. Termes. Mesosulfuron-methyl: Meeting Report of the Metabolism Assessment Review Committee. DP barcode 298760+. Office of Prevention, Pesticides, and Toxic Substances, Health Effects Division and Environmental Fate and Effects Division. Internal memorandum. Jan. 28, 2004.

### Page 65 of 318 USEPA. 2004 b . Facey, J. Thifensulfuron Methyl: Meeting Report of the Metabolism Assessment Review Committee Document. DP barcode 301509. Office of Prevention, Pesticides, and Toxic Substances, Health Effects Division. Internal memorandum. Jun. 10Dohoo, 2004.

USEPA. 2006. Standardized Soil Mobility Classification Guidance. U.S. Environmental Protection Agency, Office of Pesticide Programs, Environmental Fate and Effects Division. Internal memorandum. Apr. 21, 2006.

USEPA. 2007. Bailey, K.J., D. Dotson, and Z. Figueroa. Orthosulfamuron: Human Health Risk Assessment for Proposed Use on Rice. DP barcode 319264. Office of Prevention, Pesticides, and Toxic Substances, Health Effects Division. Memorandum to Registration Division. Feb. 14, 2007.

USEPA. 2009. Guidance for Selecting Input Parameters in Modeling the Environmental Fate and Transport of Pesticides. Version 2.1. U.S. Environmental Protection Agency, Office of Pesticide Programs, Environmental Fate and Effects Division, Oct. 22, 2009. http://www.epa.gov/oppefed1/models/water/input_parameter_guidance.htm

USEPA. 2009 a . Cutchin, W. Chlorimuron ethyl. Human Health Risk Assessment for Proposed Uses on Field Corn and Soybean. DP barcode 358796. Office of Prevention, Pesticides, and Toxic Substances, Registration Division and Health Effects Division. Internal memorandum. Sep. 14, 2009.

USEPA. 2009 b . Hanson, B. Tribenuron Methyl: Chronic Dietary (Food and Drinking Water) Exposure Assessment for the Petition Proposing Tolerances for Residues in/on Corn and Soybean. DP barcode 365813. Office of Prevention, Pesticides, and Toxic Substances, Registration Division, ARIA Team. Internal memorandum. Sep. 8, 2009.

USEPA. 2010. Scollon, E. Imazosulfuron: Report of the Residues of Concern Knowledgebase Subcommittee (ROCKS). DP barcode 377141. Office of Chemical Safety and Pollution Prevention, Health Effects Division. Internal memorandum. Jun. 22, 2010.

USEPA. 2011 a . Garber, K. and W.J. Shaughnessy. Registration Review – Addendum to thePreliminary Problem Formulation for the Ecological Risk Assessment of Chlorimuronethyl. DP barcode 388459. Office of Pesticide Programs, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Jun. 8, 2011.

USEPA. 2011 b . Holman, E. Flazasulfuron; Report of the Residues of Concern Knowledgebase Subcommittee (ROCKS). DP barcode 386767. Office of Chemical Safety and Pollution Prevention, Health Effects Division. Internal memorandum. Feb. 28, 2011.

USEPA. 2011 c . PROVISIONAL Interim EFED Guidance on Sulfonylurea Degradates in Registration Review. U.S. Environmental Protection Agency, Office of Pesticide Programs, Environmental Fate and Effects Division. Draft Guidance. Sep. 13, 2011.

### Page 66 of 318 USEPA. 2011 d . Kiernan, B. and R. Baris. Registration Review: Preliminary Problem Formulation for Environmental Fate and Ecological Risk, Endangered Species, and Drinking Water Assessments for Metsulfuron-methyl. DP barcode 389258. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Sep. 22, 2011.

USEPA. 2011 e . Kiernan, B.D. and R. Baris. Registration Review: Preliminary Problem Formulation for Environmental Fate and Ecological Risk, Endangered Species, and Drinking Water Assessments for Bensulfuron-methyl. DP barcode 389429. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Sep. 2, 2011.

USEPA 2011 f

. Clock-Rust, M. and K. White. Registration Review: Preliminary Problem Formulation for Ecological Risk and Environmental Fate, Endangered Species, and Drinking Water Assessments for Orthosulfamuron. DP 390068. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Dec. 1, 2011.

USEPA 2011 g . Parker, R. and A. Blankinship. Registration Review – Preliminary Problem Formulation for the Ecological Risk and Drinking Water Assessments of Sulfosulfuron. DP 385544. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Jun. 20, 2011.

USEPA 2011 h . Federoff, N.E. and W.J. Shaughnessy. Registration Review – Preliminary Problem Formulation for the Ecological Risk Assessment for Thifensulfuron methyl. DP 383671. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Mar. 10, 2011.

USEPA 2011 i . Wendel, C. and J. Lin. Registration Review – Preliminary Problem Formulation for the Environmental Fate, Ecological Risk, Endangered Species and Drinking Water Assessments for Tribenuron-methyl. DP 383622. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Mar. 15, 2011.

USEPA. 2012 a . Clock-Rust, M. and K. White. Registration Review – Preliminary Problem Formulation for Ecological Risk and Environmental Fate, Endangered Species, and Drinking Water Assessments for Chlorsulfuron. DP barcode 403354. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Nov. 15, 2012.

USEPA. 2012 b . Carey, S. and A. Shelby. Registration Review – Preliminary Problem Formulation for Ecological Risk and Environmental Fate, Endangered Species, and Drinking Water Assessments for Flazasulfuron. DP barcode 399093. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. May 9, 2012.

### Page 67 of 318 USEPA. 2012 c . Carey, S. and A. Shelby. Registration Review – Preliminary Problem Formulation for Environmental Fate and Ecological Risk, Endangered Species, and Drinking Water Assessments for Primisulfuron methyl. DP barcode 394823. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Mar. 1, 2012.

USEPA. 2012 d . Bohaty, R.F.H. and F.T. Farruggia. Registration Review – Preliminary Problem Formulation for Ecological Exposure and Risk Assessment for Foramsulfuron. DP barcode 402333. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Nov. 15,

2012.

USEPA. 2012 e . Barrett, M. and A. Soliday. Registration Review: Preliminary Problem Formulation for Environmental Fate and Ecological Risk, Endangered Species, and Drinking Water Assessments for Halosulfuron-methyl. DP barcode 394807. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Mar. 8, 2012.

USEPA. 2012 f

. DeCant, J. and M. Barrett. Registration Review: Preliminary Problem Formulation for Environmental Fate, Ecological Risk, Endangered Species, and Human Health Drinking Water Exposure Assessments for Rimsulfuron. DP barcode 401380. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Sep. 13, 2012.

USEPA. 2012 g . Sternberg, R. and M. Barrett. Registration Review: Preliminary Problem Formulation for Environmental Fate, Ecological Risk, Endangered Species, and Human Health Drinking Water Exposure Assessments for Sulfometuron Methyl. DP barcode 402497. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Dec. 5, 2012.

USEPA. 2012 h . DeCant, J. and G. Rothman. Registration Review: Preliminary Problem Formulation for Environmental Fate, Ecological Risk, Endangered Species, and Human Health Drinking Water Exposure Assessments for Nicosulfuron. DP barcode 397346. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Jun. 7, 2012.

USEPA. 2012 i . Milians, K. and S. Glaberman. Registration Review – Preliminary Problem Formulation for Ecological Risk and Environmental Fate, Endangered Species, and Drinking Water Assessments for Prosulfuron. DP barcode 396735. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Apr. 17, 2012.

USEPA. 2012 j . Meléndez, J. and J. Housenger. Environmental Fate and Ecological Risk Assessment Preliminary Problem Formulation in Support of Registration Review of Triflusulfuron-methyl. DP barcode 399196. Office of Chemical Safety and Pollution

### Page 68 of 318Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Reevaluation Division. Sep. 7, 2012.

USEPA. 2012 k . Ullagaddi, A. and C.M. Koper. Registration Review: Problem Formulation for the Environmental Fate and Ecological Risk, Endangered Species, and Drinking Water Exposure Assessments for Triasulfuron. DP 394283. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Mar. 5, 2012.

USEPA. 2013 a . Bohaty, R.F.H. and K.R. Stebbins. Registration Review – Preliminary ProblemFormulation for the Ecological Exposure and Risk Assessment for Iodosulfuron-methylsodium. DP barcode 404946. Office of Chemical Safety and Pollution Prevention,

Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Feb. 28, 2013.

USEPA. 2013 b . Lowit, M. and H. Zhong. Registration Review: Preliminary Problem Formulation for Environmental Fate, Ecological Risk, Endangered Species, and Drinking Water Exposure Assessments for Mesosulfuron-methyl. DP barcode 406950. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. Jun. 6, 2013.

USEPA. 2013 c . Crk, T. and J.K. Wolf. Registration Review – Preliminary Problem Formulation for the Ecological Risk Assessment for Trifloxysulfuron-sodium. DP barcode 408408. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Pesticide Re-evaluation Division. May 14, 2013.

USEPA. 2014. Rothman, G. Tier I Drinking Water Assessment for the Proposed Section 3 ALS Inhibition Tolerant Sorghum Crop New Use for the Chemical Nicosulfuron. DP 414505. Office of Chemical Safety and Pollution Prevention, Environmental Fate and Effects Division. Memorandum to Registration Division. Mar. 13, 2014.

### Page 69 of 318 Appendix A. Residues of Concern

Bensulfuron-methyl

The Bensulfuron-methyl ROCs for aquatic plants include the parent compound only. Degradates are excluded because they do not retain the SU structural group and are, therefore, assumed in the absence of study data likely to be less toxic to aquatic plants than the parent compound, based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. New environmental fate studies were requested, but not submitted to EPA in time for consideration in this assessment. If new studies identify new major degradates, the ROCs for aquatic plants may be revisited. Meanwhile, the ROCs for aquatic plants described in the PF (DP 389429, USEPA 2011 e ) have not changed for this PRA.

Chlorimuron-ethyl

The chlorimuron-ethyl ROCs for aquatic plants include the parent compound and the demethylated parent compound, the latter of which is the only degradate with a complete sulfonylurea moiety ( i.e. , an intact SU structural group). The demethylated parent compound is assumed in the absence of toxicity data likely to be no more or less toxic than the parent compound. All other degradates are cleavage products and assumed likely to be less toxic than the parent compound, based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. Recently submitted environmental fate studies (MRIDs 49526701, -02) did not identify novel major degradates for consideration. Therefore, the ROCs for aquatic plants (DP 388459, USEPA 2011 a ) have not changed for this PRA.

Chlorsulfuron

The ROCs for aquatic plants include chlorsulfuron only. Three major degradates of chlorsulfuron retain the SU structural group: O-desmethyl chlorsulfuron (IN-M6957), ring-opened chlorsulfuron (IN-JJ998), and triuret. However, toxicity studies (in review at the time of writing) indicate that IN-M6957 and IN-JJ998 are much less toxic to vascular and nonvascular plants than chlorsulfuron (MRIDs 49009404, -08, -13, and -14). Also, triuret only formed up to 13% of the applied in one studied system (MRID 49275312). Therefore, addition of triuret to the ROCs would not change exposure estimates.

All other major degradates of chlorsulfuron, including 2-chlorophenylsulfonyl urea (CPSU), are cleavage products that do not retain the SU structural group and are assumed likely to be less toxic to aquatic plants than the parent compound, based on the weight of the evidence from the toxicity of similar cleavage products of other SU compounds. Furthermore, toxicity studies(MRIDs 49009412 and -15; both in review) indicate that the chlorosulfonamide degradate (INA4097) is much less toxic to aquatic plants than the parent compound. Toxicity studies for a sulfonamide degradate of imazosulfuron (IPSN) indicate that it is much less toxic to aquatic nonvascular plants than its parent SU compound as well (MRIDs 49019005, -06, and 49485201 (each acceptable)).

### Page 70 of 318 Recently submitted environmental fate studies (MRIDs 49275301, -08, -12, -13) identified one novel major degradate for consideration, triuret. Recently submitted aquatic plant toxicity studies for degradates IN-M6957, IN-JJ998, and IN- A4097 indicated that these degradates are much less toxic to aquatic plants than chlorsulfuron. In consideration of these studies, the ROCs for aquatic plants from the PF (DP 403354, USEPA 2012 a ) have been updated for the PRA to include the parent compound only, and to exclude IN-M6957, IN-JJ998, and CPSU.

Flazasulfuron

The ROCs for aquatic plants include the parent compound only because its degradates are short lived in the environment, do not contain the SU structural group, and are less toxic to plants. Flazasulfuron degradates are similarly or more toxic to animals than the parent compound; however, their exposure in the environment is too low to be of concern (DP 399093, USEPA,

2012 b ).

Requested environmental fate studies have not been submitted at the time of writing. When they are submitted, they will be reviewed to identify any novel major degradates for consideration. In the meantime, the ROCs for aquatic plants have not changed for this PRA.

Foramsulfuron

The ROCs for aquatic plants include the parent compound, AEF130619 and F0338795. The two degradates have an intact SU structural group; therefore, they will be considered likely to be as toxic as the parent compound in the absence of additional toxicity data. A recently submitted soil photolysis study (MRID 49463901) did not identify novel degradates of concern. Therefore, the ROCs for aquatic plants (DP 402333, USEPA 2012 d ) have not changed for this PRA.

Halosulfuron-methyl

The halosulfuron-methyl ROCs for aquatic plants include the parent compound, halosulfuronmethyl guanidine, and halosulfuron acid. The latter two compounds are major degradates with intact SU structural groups that have been identified in submitted environmental fate studies [halosulfuron-methyl guanidine was up to 15% of the applied (MRID 42139410) and halosulfuron acid was up to 25% of applied (MRID 49031306)]. These degradates are assumed in the absence of toxicity data likely to be no more or less toxic than the parent compound.

A recently submitted aerobic soil metabolism study (MRID 49031306) did not identify novel degradates of concern. However, the ROCs for aquatic plants stated in the PF (DP 394807;

USEPA 2012 e ) have changed for this PRA to include the major SU degradates halosulfuronmethyl guanidine and halosulfuron acid.

Imazosulfuron

The ROCs for aquatic plants include the parent compound, HMS, and SDPM because these compounds have an intact SU structural group and toxicity data are not available for the

### Page 71 of 318 degradates. HMS and SDPM are assumed in the absence of toxicity data likely to be no more or less toxic than the parent compound.

Cleavage products included in the new chemical assessment (IPSN, ADPM, and UDPM) are not included in the residues of concern for this PRA because they do not have an intact SU group. Additionally, submitted studies for IPSN (the cleavage product most structurally similar to the parent compound) indicate it is less toxic than imazosulfuron to aquatic plants. An IPSNtoxicity study submitted for green algae (MRID 49485201, which is in review) yields a nondefinitive (greater than) EC 50 

### endpoint at the limit of solubility (10 mg ai/L) under the test conditions. A comparison of the values from that toxicity study (EC 50 

### >10 mg ai/L) and other reviewed toxicity studies for IPSN to that of an ECOTOX study (ref. no. 104861, Mohammad et
al. 2005) for the parent compound indicates that, compared to imazosulfuron, IPSN is at least 4 orders of magnitude less toxic to aquatic vascular ( Lemna gibba ) plants and at least one order of magnitude less toxic to aquatic non-vascular plants ( Pseudokirchneriella subcapitata ). All endpoints for the degradate toxicity studies were non-definitive (greater than), which further supports that IPSN is likely to be less toxic than the parent compound to aquatic plants (MRIDs 47305213, 49019003, -04, -05, -06, 49485201-in review).

Iodosulfuron-methyl-sodium

The ROCs for aquatic plants include the parent compound and four degradates, metsulfuronmethyl, AEF145740, AE 0002166, and AE 0014965. These four degradates have an intact SU structural group, and will be considered likely to be no more or less toxic than the parent compound in the absence of toxicity data. There are two other degradates with an intact SU group (AE F161778 and AE 0014966), for which available toxicity data suggest both are less toxic than the parent compound to aquatic vascular plants (Lemna gibba) with EC 50 

### values of 0.418 mg/L for AE F161778 (MRID 46319201) and >10 mg/L for AE 0014966 (MRID 45791502). Of the four degradates of concern, AE 0014965 only forms in anaerobic conditions and is not likely to be a prominent degradate, with the possible exception that it may be found in ground water. No environmental fate studies have been recently submitted and no novel degradates of concern have been identified. Thus, after considering the new toxicity data, the ROCs for aquatic plants identified in the PF (DP 404946, USEPA 2013 a ) have been reduced for this PRA to include only metsulfuron-methyl, AEF145740, AE 0002166, and AE 0014965.

Mesosulfuron-methyl

The mesosulfuron-methyl ROCs for aquatic plants are different for vascular and nonvascular taxa. For vascular plants, the ROCs include the parent compound only. Studies conducted on degradates of mesosulfuron-methyl (one of which, regarding DOP urea, is under review) indicate that they are less toxic than the parent compound to vascular plants regardless of whether the degradates contain an intact SU structural group (DP 406950, USEPA 2013 b ).

For non-vascular plants, the ROCs include the parent compound, AE F154851, and AE F160460. ECOSAR predictions of toxicity to nonvascular plants for the two degradates are within an order of magnitude of that for the parent compound (DP 406950, USEPA 2013 b ). ECOSAR was used to predict toxicity for these compounds because acceptable nonvascular plant toxicity studies are

### Page 72 of 318 not available for mesosulfuron-methyl or for these degradates. ECOSAR results should be interpreted with caution given that definitive experimental endpoint values are not available for the parent compound; however, the results do not provide clear evidence that these degradates are less toxic than the parent compound. Therefore, in the absence of study data, AE F154851 and AE F160460 cannot be excluded as ROCs. Comparison of study values for AE F099095 (MRID 49137503-in review), AE F160459, and AE F147447 to ECOSAR predictions for the parent compound suggests that these degradates are likely to be much less toxic than the parent compound to nonvascular plants. ECOSAR predicts that AE F140584 and AE F092944 are less toxic than the parent compound as well. Therefore, AE F099095, AE F160459, AE F147447, AE F140584, and AE F092944 are not included in the ROCs.

No environmental fate studies have been recently submitted and no novel degradates of concern have been identified. The ROCs for aquatic plants discussed in the PF (DP 406950, USEPA

2013 b ) have been updated for this PRA to reflect new toxicity data and to address vascular plants separately from nonvascular plants using the available study data and ECOSAR predictions.

Metsulfuron-methyl

The metsulfuron-methyl ROCs for aquatic plants include the parent compound, IN-NC148, INS9H62, IN-F5438, IN-JX909, and IN-MU717. These degradates are included because they retain the SU structural group and are assumed likely to be equal to the parent compound in toxicity to aquatic plants in the absence of data. The SU degradate IN-B5067 is not included because a submitted study indicates that it is much less toxic to vascular aquatic plants than the parent compound (MRIDs 46319201). New environmental fate studies have been submitted recently, identifying eight novel major degradates including IN-S9H62 and IN-D5119 (MRID 49154302), IN-F5438 and IN-V7160 (MRID 49154304), IN-F5438 and IN-JX909 (MRID 49154307), and IN-MU717 and IN-F5475 (MRID 49480102). The ROCs for aquatic plants described in the PF (DP 389258, USEPA 2011 d ) have been updated for this PRA to include the major degradates with an intact SU structural group identified in submitted environmental fate

studies and to exclude IN-B5067.

Nicosulfuron

The nicosulfuron ROCs for aquatic plants include the parent compound, IN-37740, and INHYY21. The degradates of concern are major degradates that retain the SU structural group and that are assumed likely to be equal to the parent compound in toxicity to aquatic plants in the absence of data. One environmental fate study has been recently submitted (MRID 49169703), in which IN-HYY21 was a major degradate in multiple soils. The ROCs for aquatic plants proposed in the PF (DP 397346, USEPA 2012 h ) have changed for this PRA to exclude INV9367 and IN-J029 because these compounds do not have an intact SU structural group and are, therefore, not expected to be as toxic to plants as the parent compound.

Orthosulfamuron

The ROCs for aquatic plants include the parent compound and O-desmethyl orthosulfamuron, the latter of which is the only major degradate with an intact SU structural group. The

### Page 73 of 318 demethylated parent compound is assumed likely to be no more or less toxic than the parent compound. All other degradates are cleavage products and demonstrated or assumed likely to be less toxic than the parent compound based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. Recently submitted studies in review (MRIDs 49137503 and 49137504) indicate that DOP urea is much less toxic than orthosulfamuron to nonvascular and vascular aquatic plants, which is consistent with the toxicity data for other cleavage products of SU compounds. Therefore, DOP urea and O-desmethyl DOP urea are excluded from the ROCs for aquatic plants.

Recently submitted environmental fate studies (MRIDs 49555902, -03, -04, -05) did not identify novel major degradates for consideration. The ROCs for aquatic plants proposed in the PF (DP 390068, USEPA 2011 f

) have changed for this PRA to exclude DOP urea and O-desmethyl DOP

urea.

Primisulfuron-methyl

The ROCs for aquatic plants include the parent compound and demethylated parent compound (CGA-191429), the latter of which is the only major degradate with an intact SU structural group. The demethylated parent compound is assumed likely to be no more or less toxic than theparent compound. All other degradates (CGA-120844, CGA-171683, CGA-219741, CGA177288, CGA-147087, CGA-177289, and CGA-239771) are cleavage products and assumed likely to be less toxic to aquatic plants than the parent compound based on the results of toxicity studies conducted on cleavage products of other SUs. Recently submitted environmental fate studies (MRIDs 49125201, -02) identified two novel major degradates for consideration, demethylated parent compound (CGA-191429) and CGA-239771. Because CGA-239771 is a cleavage product, it is assumed likely to be less toxic than the parent compound to aquatic plants.

The ROCs for aquatic plants proposed in the PF (DP 394823, USEPA 2012 c ) have changed for this PRA because CGA-171683 is a cleavage product that is predicted by ECOSAR to be much less toxic to algae than the parent compound and demethylated parent compound, a degradate with an intact SU structural group, was not identified previously. Therefore, CGA-171683 has been removed from the ROCs and demethylated parent compound has been added.

Prosulfuron

The ROCs for aquatic plants include the parent compound, CGA-300406, CGA-325025, CGA325028, and CGA-325030. The degradates of concern are major degradates with an intact SU structural group that are assumed likely to be no more or less toxic than the parent compound. All other degradates are minor SU degradates or cleavage products that are assumed likely to be less toxic than the parent compound based on ECOSAR predictions and FOOTPRINT database

data.

No environmental fate studies have been submitted recently and no novel degradates of concern have been identified for consideration. The ROCs for aquatic plants proposed in the PF (DP 396735, USEPA 2012 i ) have changed for this PRA to exclude minor degradates with an intact SU structural group.

### Page 74 of 318 Rimsulfuron

The rimsulfuron ROCs for aquatic plants include the parent compound only. Rimsulfuron does not produce major degradates in the environment that retain the SU structural group. No 

### environmental fate studies have been recently submitted and no degradates of exposure concern have been identified. Therefore, the ROCs for ERA (DP 401380, USEPA 2012 f

) have not changed for this PRA.

Sulfometuron-methyl

The sulfometuron-methyl ROCs for aquatic plants include the parent compound only. ECOSAR predicts the major degradates are much less toxic to plants than the parent compound. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. Therefore, the ROCs for ERA (DP 402497, USEPA 2012 g ) have not changed for this PRA.

Sulfosulfuron

The sulfosulfuron ROCs for aquatic plants include the parent compound only. Recently submitted studies (in review) indicate that major degradates with an intact SU structural group ( i.e. , the desmethyl and sulfamic acid degradates) are much less toxic to vascular and nonvascular aquatic plants than the parent compound (MRIDs 49283904, -05, -08, and -09). Degradates without the SU structural group are expected likely to be less toxic to plants than those with the SU structural group. Therefore, all degradates are expected likely to be much less toxic to aquatic plants than sulfosulfuron. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. Therefore, the ROCs for ERA (DP 385544, USEPA 2011 g ) have changed for this PRA to exclude all degradates.

Thifensulfuron-methyl

The ROCs for aquatic plants include the parent compound, IN-L9225, IN-L9226, and IN-JZ789. The degradates of concern are the major degradates with an intact SU structural group. They are assumed in the absence of data likely to be no more or less toxic than the parent compound. All other degradates are cleavage products and assumed likely to be less toxic than the parent compound based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. Therefore, the ROCs for aquatic plants proposed in the PF (DP 383671, USEPA 2011 h ) have changed for this PRA to exclude major cleavage products.

Triasulfuron

The ROCs for aquatic plants include the parent compound, CGA-195660, SYN546702, and the sulfonic acid derivative of CGA-183859. The degradates of concern are the major degradates with an intact SU structural group. They are assumed in the absence of data likely to be no more

### Page 75 of 318 or less toxic to aquatic plants than the parent compound. All other major degradates are cleavage products that are assumed likely to be less toxic to aquatic plants than the parent compound, based on the weight of the evidence from the toxicity of similar cleavage products of other SU compounds. More specifically, studies (MRIDs 49009412 and -15 (both in review) and 49019005, -06, and 49485201 (each acceptable)), indicate that sulfonamide degradates of

chlorsulfuron and imazosulfuron have EC 50 

### values >9.5 mg/L, indicating that this class of compounds (including triasulfuron’s sulfonamide degradates CGA-161149 and CGA-195654) is much less toxic to aquatic plants than the SU class of compounds.

Five environmental fate studies have been submitted recently (MRIDs 49126701, -02, -03, -05, and -06). SYN546702 is a novel degradate of concern identified in three of these studies. Therefore, the ROCs for aquatic plants proposed in the PF (DP 394283, USEPA 2012 k ) have changed for this PRA to include the new major SU degradate, SYN546702.

Tribenuron-methyl

The ROCs for aquatic plants include the parent compound only. Major degradates of tribenuronmethyl other than its O-desmethyl degradate are cleavage products and are assumed likely to be less toxic than the parent compound, based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. The O-desmethyl degradate is not of concern because it was not a prominent degradate, being just over 10% of the applied in only one anaerobic
system. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. Therefore, the ROCs for aquatic plants proposed in the PF (DP 383622, USEPA 2011 i ) have changed for this PRA to exclude the cleavage products saccharin, triazine amine, O-desmethyl-triazine amine, and sulfonamide.

Trifloxysulfuron-sodium

The ROCs for aquatic plants include the parent compound only. The major degradates of trifloxysulfuron-sodium do not have an intact SU structural group and are assumed likely to be less toxic than the parent compound, based on submitted toxicity studies (MRIDs 45371729 and 45371727) and the weight of the evidence from the toxicity of cleavage products of other SU compounds. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. The ROCs for aquatic plants proposed in the PF (DP 408408, USEPA 2013 c ) have changed for this PRA to exclude the minor SU products CGA292230 and NOA-440735.

Triflusulfuron-methyl

The ROCs for aquatic plants include the parent compound and its N-desmethyl and free acid degradates. The degradates of concern are major demethylation degradates with an intact SU structural group. They are assumed in the absence of toxicity data likely to be no more or less toxic than the parent compound. All other degradates are cleavage products and assumed likely to be less toxic than the parent compound, based on the weight of the evidence from the toxicity of cleavage products of other SU compounds. No 

### environmental fate studies have been submitted recently and no new degradates of exposure concern have been identified. The ROCs for aquatic

### Page 76 of 318 plants proposed in the PF (DP 399196, USEPA 2012 j ) have changed for this PRA to include the major demethylation degradates.

### Page 77 of 318 Appendix B. Exposure Model Files

GENEEC Aquatic Modeling Output Files

Geneec files.zipPage78of318Appendix C. Environmental Fate Data and Chemical Structures of the Sulfonylureas and their DegradatesEnvironmental Fate DataIn support of this assessment, environmental fate data regardingthe sulfonylureas and their degradates were collected from theproblem formulations for registration review and, in some cases,directly from studies submitted to EPA. There data are tabulated inthe attached Microsoft Excel workbook.SU PRA Fate DataFINAL.xlsChemical StructuresBensulfuron-methylCAS Name Chemical Reference Structure Study MRID NotesBensulfuron-methyl DPX F5384 -- -- --2-amino-4,6-dimethoxypyrimidinepyrimidine amineAerobic Soil 00073657 one of three identifiable, nonvolatile degradatesAerobicAquatic40089329 max concentration 9.5 - 15% ofappliedHydrolysis 00073657 at pH 5, otherwise stable underneutral and alkaline conditionsPage79of318methyl 2-(aminosulfonylmethyl)benzoatesulfonamideAerobic Soil 00073657 one of three identifiable, non-volatile degradatesAerobicAquatic40089329 max concentration 6.2 - 7.6% ofappliedHydrolysis 00073657 at pH5, otherwise stable underneutral and alkaline conditionsSoil ColumnLeaching00073657 12%Photodegradation40089330 max concentration 8.3%IH2,3-benzothiazin-4(3H)-one2,2-dioxideHomosaccharineAerobic Soil 00073657 one of three identifiable, nonvolatile degradatesAerobicAquatic40089329 also detectedN-(4,6-dimethoxy-2-pyrimidinyl )ureapyrimidinyl urea Photodegradation40089330 Max Concentrations 11.9%3-hydroxypropanoic acid Photodegradation00073657 Max concentration 23%Page80of318Chlorimuron-ethylChemical name Structure Fate study Maximum %formed (day ofstudy where thiswas observed)Reference(MRID)GuidelinesofrequestedstudiesEthyl 2-(4-chloro-6-methoxypyrimidin-2-ylcarbamoylsulfamoyl)benzoate(Chlorimuron-ethyl;parent)Not applicable Not applicableNotapplicable835.4100Benzoid acid, 2-[[(4-chloro-6-hydroxyprimidin-2-yl)aminocarbonyl]aminoxulfonyl],ethyl ester(“demethylatedparent”)Aerobic soil metabolism118.6% (wk 24) 145402 None,assumedto beequaltoxic toparent.Aerobic soil metabolism213.2 % (wk 52) 145402Anaerobic aquatic metabolism363.6% (wk 16) 145777Anaerobic aquatic metabolism4Approx 100%(wk 16)145777Terrestrial field dissipation516.8% (wk 16) 145780Terrestrial field dissipation65.7% (wk 26) 145780Terrestrial field dissipation75.8% (wk 18) 145780Terrestrial field dissipation87.9% (wk 2) 1457802-(Aminosulfonyl)benxoic acid, ethyl ester(“sulfonamide”)Hydrolysis (pH 5) 65% (d 30) 131580 850.4100,850.4400,850.5400Aerobic soil metabolism136.8 % (wk 24) 145402Aerobic soil metabolism260.1 % (wk 24) 145402Anaerobic aquatic metabolism37.3 % (wk 8) 145777Anaerobic aquatic metabolism4<0.1% 145777Terrestrial field dissipation59.7% (wk 26) 145780Terrestrial field dissipation664% (wk 16) 145780Terrestrial field dissipation78.8% (wk 18) 145780Terrestrial field dissipation(North Carolina soil)17.7% (wk 0) 145780HNHNONNOClSOOOHNHNONNOHClSOOONH2SOOOPage81of318Chemical name Structure Fate study Maximum %formed (day ofstudy where thiswas observed)Reference(MRID)GuidelinesofrequestedstudiessaccharinAerobic soil metabolism117.6% (wk 52) 145402 850.4100,850.4400,850.5400Aerobic soil metabolism231.2% (wk 4) 145402Anaerobic aquatic metabolism316.0 % (wk 26) 145777Anaerobic aquatic metabolism46.6 % (wk 26) 145777Terrestrial field dissipation520.2% (wk 0) 145780Terrestrial field dissipation625.5% (wk 16) 145780Terrestrial field dissipation715.6% (wk 8) 145780Terrestrial field dissipation825.7% (wk 2) 1457804-Chloro-6-methoxy-2-pyrimidianamine(“pyrimidine-amine”)Hydrolysis (pH 5) 78% (d 30) 131580 850.4100,850.4400,850.5400Aerobic soil metabolism139.4 % (wk 8) 145402Aerobic soil metabolism244.5 % (wk 24) 145402Anaerobic aquatic metabolism34.7% (wk 8) 145777Anaerobic aquatic metabolism4<0.1% 145777Terrestrial field dissipation514.7% (wk 16) 1457804-chloro-6-hydroxy-2pyrimidinamine(“demethyl pyrimidineamine”)Terrestrial field dissipation511.7% (wk 8) 145780 850.4100,850.4400,850.54004-hydroxy-6-methoxy2-pyrimidinamine(“dechlorinatedpyrimidine amine”)Terrestrial field dissipation512.7% (wk 4) 145780 850.4100,850.4400,850.54001woodstown sandy loam2Flanagan silt loam3PA hydrosoil4FL hydrosoil5Delaware soil6Illinois soil7Mississippi soil8North Carolina soilSNHOOOH2NNNOCl+H2NNNOHCl+H2NNNOOH+Page82of318ChlorsulfuronChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aCommon Name:Chlorsulfuron (CSF)IUPAC Name:2-chloro-N1-(2-chlorophenylsulfonyl)-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureaCAS name:2-chloro-N-[[(4-methoxy-6-methyl1,3,5-triazin-2-yl)amino]carbonyl]benzenesulfonamideOther names:DPX-4189; IN-W4189CAS No: 64902-72-3SMILES:Clc1ccccc1S(=O)(=O)NC(=O)Nc2nc(nc(OC)n2)CMW=357.77Hydrolysis 4215670139 (31 days), pH 5, ph40 (31 days), pH 5, tri99 (31 days), pH 7, ph97 (31 days), pH 7, tri96 (31 days), pH 9, ph98 (31 days, pH 9, triAqueousphotolysis4215670297 (31 days) light, pH 7, ph99 (31 days) dark, pH 7, ph98 (31 days), light, pH 7, tri97 (31 days), dark, pH 7, triSoil photolysis417210014215670375.7 (73.6 days) triAerobic Soil 000352757.4 (180 days), 1 mg/kg, ph6.7 (180 days, 0.1 mg/kg, phAnaerobicAquatic4215670454 (365 days), PA, tri75 (70 days), PA, phe50 (56 days), Canada, phe82 (35 days), NE, phe66 (28 days), IL, pheCommon Name: O-desmethylchlorsulfuron(ODMC)Other Names:2-chloro-N-[[(4-hydroxy-6-methyl1,3,5-triazine-2-yl)-amino)carbonyl]benzenesulfanamide; 5-hydroxychlorsulfuron (OHCSF); IN-M6957SMILES:ClC1=C(C=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)C)O[H]MW=343.75Log KOW=1.20 (estimated)Hydrolysis 4215670113 (21 days), pH 5, ph14 (21 days), pH 5, triND pH 7, ph1 (31 days), pH 7, tri1 (31 days), pH 9, ph2 (31 days, pH 9, tri10 (31 days), pH 5, ph12 (31 days), pH 5, triND (31 days), pH 7, ph1 (31 days), pH 7, tri1 (31 days), pH 9, ph2 (31 days, pH 9, triAqueousphotolysis421567021.4 (31 days), pH 7 light, ph0.5 (31 days), pH 7 dark, ph0.9 (21 days), light, pH 7, tri1.1 (31 days), dark, pH 7, tri1.4 (31 days), pH 7 light, ph0.5 (31 days), pH 7 dark, ph0.9 (21 days), light, pH 7, tri1.1 (31 days), dark, pH 7, triSoil photolysis41721001421567032.8 (74 days), tri 2.8 (74 days), triAerobic Soil 00035275 NANAPage83of318ChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aAnaerobicAquatic14215670431 (365 days), PA, tri11 (70 days), PA, phe18 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, phe31 (365 days), PA, tri11(70 days), PA, phe18 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, pheCommon Name:Ring-opened chlorsulfuron(ROC)Other Names:1-(2-chlorophenylsulfonyl)-7-acetyltriuret;2-chloro-N-[[[[[[(2-oxethyl)amino]carbonyl]amino]carbonyl]-amino]carbonyl]benzenesulfanamide; IN-JJ998SMILES:C1=CC=CC(=C1Cl)[S](N(C(N(C(N(C(N([H])[H])=O)[H])=N[H])[H])=O)[H])(=O)=OMW=319.72Log KOW=1.31 (estimated)Hydrolysis 4215670116 (31 days), pH 5, ph18 (31 days), pH 5, triND (31 days), pH 7, phND (31 days), pH 7, triND (31 days), pH 9, phND (31 days, pH 9, tri16 (31 days), pH 5, ph18 (31 days), pH 5, triND (31 days), pH 7, phND (31 days), pH 7, triND (31 days), pH 9, phND (31 days, pH 9, triAqueousphotolysis42156702 NR pH 7 NR pH 7Soil photolysis4172100142156703NR NRAerobic Soil 00035275 NANAAnaerobicAquatic14215670431 (365 days), PA, tri11 (70 days), PA, phe18 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, phe31 (365 days), PA, tri11(70 days), PA, phe18 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, phePage84of318ChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aCommon Name:Chlorosulfonamide (CSM)Other names:2-chlorobenzenesulfanamide; INA4097CAS#: 6961-82-6SMILES:C1=CC=CC(=C1Cl)S(N([H])[H])(=O)=OMW=191.63Log KOW=0.74 (experimental)Hydrolysis 4215670133(31 days), pH 5, phNA (31 days), pH 5, tri1 (31 days), pH 7, phNA (31 days), pH 7, tri2 (31 days), pH 9, phNA (31 days, pH 9, tri33(31 days), pH 5, phNA(31 days), pH 5, tri1 (31 days), pH 7, phNA (31 days), pH 7, tri2 (31 days), pH 9, phNA(31 days, pH 9, triAqueousphotolysis421567021.7 (31 days), pH 7 light, ph1.0 (21 days), pH 7 dark, phNA, pH 7, tri1.7(31 days), pH, 7 light, ph0.8 (31 days), pH 7 dark, phNA, pH 7, triSoil photolysis4172100142156703NR NRAerobic Soil 00035275 NANAAnaerobicAquatic42156704NR (365 days), PA, tri14 (70 days), PA, phe11 (56 days), Canada, phe17 (21 days), NE, phe13 (28 days), IL, pheNR (365 days), PA, tri14(70 days), PA, phe11 (56 days), Canada, phe3 (35 days), NE, phe13 (28 days), IL, pheCommon Name:Triazine amine (TA)Other Names:2-amino-4-methoxy-6-methyl1,3,5-triazine; IN-A40981;CGA150829CAS #: 1668-54-8SMILES:C1(=NC(=NC(=N1)C)N([H])[H])OCMW=140.15Log KOW=1.26 (estimated)Hydrolysis 42156701NA (31 days), pH 5, ph17 (31 days), pH 5, triazineNA(31 days), pH 7, ph1 (31 days), pH 7, triazineNA (31 days), pH 9, ph1 (31 days, pH 9, triazineNA (31 days), pH 5, ph17(31 days), pH 5, triazineNA (31 days), pH 7, ph1 (31 days), pH 7, triazineNA (31 days), pH 9, ph1 (31 days, pH 9, triazineAqueousphotolysis42156702 NR pH 7 NR pH 7Soil photolysis41721001421567035.5 (74 days), tri 5.5 (74 days), triAerobic Soil 00035275 NANAAnaerobicAquatic4215670421 (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, phe21 (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, phePage85of318ChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aCommon Name:2-chlorophenylsulfonylurea(CPSU)Other Names:2-chloro-N-(aminocarbonyl)benzenesulfanamideSMILES:C1=CC=CC(=C1Cl)S(NON)(=O)=OMW=222.65Log KOW= -1.74 (estimated)AnaerobicAquatic42156704NA (365 days), PA, tri3.1 (7 days), PA, phe14 (56 days), Canada, phe12 (35 days), NE, phe9.1 (28 days), IL, pheNA(365 days), PA, tri2.1 (70 days), PA, phe14 (56 days), Canada, phe12 (35 days), NE, phe9.1 (28 days), IL, pheCommon Name:Dihydroxy Triazine (DT)Other Names:2,4-dihydroxy-6-methyl-1,3,5-triazine (IN-F5475)SMILES:C1(=NC(=NC(=N1)O[H])C)O[H]MW=127.10Log KOW=0.89 (estimated)Hydrolysis 42156701NA (31 days), pH 5, ph9 (31 days), pH 5, triazineNA (31 days), pH 7, phND (31 days), pH 7, triazineNA (31 days), pH 9, phND (31 days, pH 9, triazineNA (31 days), pH 5, ph9 (31 days), pH 5, triazineNA (31 days), pH 7, phND(31 days), pH 7, triazineNA (31 days), pH 9, phND (31 days, pH 9, triazineSoil photolysis41721001421567031.2 (74 days), tri 1.2 (74 days), triAerobic Soil 00035275 NANAAnaerobicAquatic42156704NA (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, pheNA (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, pheO-desmethyl triazine amine (ODMTA)Structure not providedAnaerobicAquatic42156704<0.1 (365 days), PA, tri<0.1 (70 days), PA, phe<0.1 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, phe<0.1 (365 days), PA, tri<0.1 (70 days), PA, phe<0.1 (56 days), Canada, phe<0.1 (35 days), NE, phe<0.1 (28 days), IL, phePage86of318ChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aCommon Name:Triazine Urea (TU)Other Names:IN-V71603SMILES:C1(=NC(=NC(=N1)OC)NC(N)=O)CMW=183.17Log KOW=0.89 (estimated)Hydrolysis 42156701 NA NAAqueousphotolysis42156702 NR pH 7 NR pH 7Soil photolysis41721001421567037.6 (74 days), tri 7.6 (74 days), triAerobic Soil 00035275 NA NAAnaerobicAquatic42156704NR (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, pheNR (365 days), PA, triNA (70 days), PA, pheNA (56 days), Canada, pheNA (35 days), NE, pheNA (28 days), IL, pheOthers/ Individual Unknowns Hydrolysis 4215670122 (31 days)Aqueousphotolysis42156702 NR pH 7 NR pH 7Soil photolysis41721001421567031.7 (53 days), tri 1.6 (74 days), triAerobic Soil 0003527552.9 (180 days)60.4 (180 days)52.9 (180 days)60.4 (180 days)Unextracted residuesSoil photolysis41721001421567037.2 (18 days), light, tri8.8 (7 days), dark, tri9.7 (77 days), light, ph6.2 (31 days), dark, ph3.8 (74 days), light, tri3.5 (31 days, dark, tri9.7 (77 days), light, ph6.2 (31 days), dark, phAerobic Soil 000352759 (120 days), 0.1 mg/kg, ph7 (120 days), 1 mg/kg, ph5 (120 days), 0.1 mg/kg, ph5 (120 days), 1 mg/kg, phAnaerobicAquatic421567044 (365 days), PA, tri2 (28 days), PA, phe14 (56 days), Canada, phe14 (21 days), NE, phe13 (28 days), IL, phe4 (365 days), PA, tri1 (70 days), PA, phe14 (56 days), Canada, phe10 (35 days), NE, phe13 (28 days), IL, pheCO2Soil photolysis4172100142156703<0.9 (74 days), light, tri<0.5 (31 days), dark, tri8.0 (31 days), light, ph<1 (31 days), dark, ph<0.9 (74 days), light, tri<0.5 (31 days), dark, tri8.0 (31 days), light, ph<1 (31 days), dark, phAerobic Soil 000352755 (180 days), 0.1 mg/kg, ph5 (180 days), 1 mg/kg, ph5 (120 days), 0.1 mg/kg, ph5 (120 days), 1 mg/kg, phPage87of318ChemicalStudy TypeMRIDMaximum %AR (day)aFinal %AR (study length)aTotal VolatilesSoil photolysis4172100142156703<2.5 (74 days), light, tri<2.1 (74 days), dark, tri8 (31 days), light, ph<3.3 (31 days), dark, ph<2.5 (74 days), light, tri<2.1 (74 days), dark, tri8 (31 days), light, ph<3.3 (31 days), dark, phND=not detected; NA=not analyzed; NR=notreported in DER; ph=phenyl ring radiolabed; tri=triazine ring radiolabeled1The study reported total amount of polar compounds and indicated that the polar compounds were o-desmethyl chlorsulfuron or ring-opened chlorsulfuron. Thetotal amount reported as polar compounds were reported for o-desmethyl chlorsulfuron and ring-opened chlorsulfuron.Code Name/SynonymChemical NameChemical StructureStudyTypeMRIDMaximum %AR (day)Final %AR(study length)Triazine amine(IN-A4098;AE F059411;BCSCN85650;CGA-150829)IUPAC:2-Amino-4-methoxy-6-methyl-1,3,5-triazinCAS:4-Methoxy-6-methyl-1,3,5-triazin-2-amineCAS No.:1668-54-8Formula:C5H8N4OMW:140.1 g/molSMILES:[H]N([H])c1nc(nc(n1)OC)C835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam18.4%(62 d)18.1%(120 d)Silty clay16.5%(120 d)16.5%(120 d)Nambsheimsandy loam12.9%(120 d)12.9%(120 d)Silt loam25.7%(120 d)25.7%(120 d)Suchozebrysandy loam25.0%(120 d)25.0%(120 d)49275308 Loam 8.2% (120 d) 8.2% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam17.8%(102 d)17.8%(102 d)49275313Pondwater:loamysand1.6% (100 d) 1.6% (100 d)Pondwater:loam5.5% (120 d) 5.5% (120 d)Page88of318Code Name/SynonymChemical NameChemical StructureStudyTypeMRIDMaximum %AR (day)Final %AR(study length)Ring-openedchlorsulfuron(IN-JJ998)IUPAC:N-[[[[(aminocarbonyl)amino]iminomethyljamino]carbonyl]-2-chlorobenzenesulfonamideCAS No.:208252-66-8Formula:C9H10ClN5O4SMW:319.7 g/molSMILES:[H]/N=C(/N([H])C(=O)N([H])[H])\N([H])C(=O)N([H])S(=O)(=O)c1ccccc1C835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam36.7%(62 d)32.9%(120 d)Silty clay17.0%(120 d)17.0%(120 d)Nambsheimsandy loam24.2%(120 d)24.2%(120 d)Silt loam 8.7% (120 d) 8.7% (120 d)Suchozebrysandy loam18.9%(120 d)18.9%(120 d)49275308 Loam 7.2% (120 d) 7.2% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam2.0% (102 d)2.0% (102 d)49275313Pondwater:loamysand27.4%(100 d)27.4%(100 d)Pondwater:loam2.9% (120 d)2.9% (120 d)O-desmethylchlorsulfuron(IN-M6957)IUPAC:1-(2-Chlorophenyl)sulfonyl-3-(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)ureaCAS:2-Chloro-N-[[(1,4-dihydro-6-methyl-4-oxo-1,3,5-triazin-2-yl)amino]carbonyl]-(9CI)CAS No.:135701-76-7Formula:C11H10ClN5O4SMW:343.75 g/molSMILES:[H]N(c1nc(nc(n1)O)C)C(=O)N([H])S(=O)(=O)c2ccccc2Cl835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam12.5%(7 d)2.6% (120 d)Silty clay15.5%(62 d)13.7%(120 d)Nambsheimsandy loam15.3%(62 d)12.4%(120 d)Silt loam10.0%(94 d) 7.1% (120 d)Suchozebrysandy loam12.3%(90 d)11.8%(120 d)49275308 Loam 4.0% (120 d) 4.0% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam22.4%(102 d)22.4%(102 d)49275313Pond water:loamy sand42.5%(50 d)32.6%(100 d)Pondwater:loam5.2% (120 d) 5.2% (120 d)Page89of318Code Name/SynonymChemical NameChemical StructureStudyTypeMRIDMaximum %AR (day)Final %AR(study length)Chlorosulfonamide (IN-A4097)IUPAC:2-ChlorobenzenesulfonamideCAS No.:6961-82-6Formula:C6H6ClNO2SMW:191.6 g/molSMILES:[H]N([H])S(=O)(=O)c1ccccc1Cl835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam24.8%(120 d)24.8%(120 d)Silty clay15.8%(120 d)15.8%(120 d)Nambsheimsandy loam8.5% (120 d)8.5% (120 d)Silt loam34.9%(120 d)34.9%(120 d)Suchozebrysandy loam29.2%(120 d)29.2%(120 d)49275308 Loam 3.3% (120 d) 3.3% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam10.1%(102 d)10.1%(102 d)49275313Pond water:loamy sand3.3% (100 d)3.3% (100 d)Pondwater:loam3.6% (120 d)3.6% (120 d)TriuretIUPAC:(NZ)-N-[[(Z)-[[(2-chlorophenyl)sulfonylcarbamoylamino]-hydroxy-methylene]amino]-hydroxymethylene]acetamideFormula:C11H11ClN4O6SMW:362.75 g/molSMILES:[H]N(/C(=N/C(=N/C(=O)C)/O)/O)C(=O)N([H])S(=O)(=O)c1ccccc1Cl835.4300Aerobicaquaticmetabolism49275312Water:sandyloam13.4%(102 d)13.4%(102 d)Carbon dioxideIUPAC:Carbon dioxideFormula:CO2MW:44 g/molSMILES:C(=O)=O835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam9.7%(120 d)9.7%(120 d)Silty clay 3.1% (120 d) 3.1% (120 d)Nambsheimsandy loam3.3% (120 d)3.3% (120 d)Silt loam10.7%(120 d)10.7%(120 d)Suchozebrysandy loam10.5%(120 d)10.5%(120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam3.7% (102 d)3.7% (102 d)49275313Pond water:loamy sand1.9% (100 d)1.9% (100 d)Pondwater:loam2.9% (120 d)2.9% (120 d)Page90of318Code Name/SynonymChemical NameChemical StructureStudyTypeMRIDMaximum %AR (day)Final %AR(study length)UnextractableresiduesNA NA835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam35.9%(120 d)35.9%(120 d)Silty clay24.9%(120 d)24.9%(120 d)Nambsheimsandy loam26.0%(120 d)26.0%(120 d)Silt loam39.3%(120 d)39.3%(120 d)Suchozebrysandy loam28.9%(120 d)28.9%(120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam11.3%(102 d)11.3%(102 d)49275313Pond water:loamy sand25.6%(100 d)25.6%(100 d)Hydroxytriazine amine(IN-B5528;acetoguanide)IUPAC:4-Amino-6-methyl-1,3,5-triazin-2-olCAS:4-Amino-6-methyl-1,3,5-triazin2(1H)-oneCAS No.:16352-06-0Formula:C4H6N4OMW:126.1 g/molSMILES:[H]N([H])c1nc(nc(n1)O)C835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam1.1% (120 d)1.1% (120 d)Silty clay 0.1% (30, 120 d) 0.1% (120 d)Nambsheimsandy loam0.7% (120 d)0.7% (120 d)Silt loam 0.4% (30, 94, 120 d) 0.4% (120 d)Suchozebrysandy loam1.7% (120 d)1.7% (120 d)49275308 Loam 0.9% (14 d) 0.6% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam7.8% (102 d)7.8% (102 d)49275313Pond water:loamy sand0.7% (41 d)0.2% (100 d)Pondwater:loam0.1% (70, 120 d)0.1% (120 d)Page91of318Code Name/SynonymChemical NameChemical StructureStudyTypeMRIDMaximum %AR (day)Final %AR(study length)Triazine urea(IN-V7160)CAS:(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)ureaCAS No.:208252-67-9Formula:C6H9N5O2MW:183.17 g/molSMILES:[H]N([H])C(=O)N([H])c1nc(nc(n1)OC)C835.4100Aerobicsoilmetabolism49275301Mattapex #25Sandy loam0.4% (3, 7, 14 d)0.2% (120 d)Silty clay 0.3% (3 d) 0.0% (120 d)Nambsheimsandy loam0.3% (3 d)0.0% (120 d)Silt loam 0.3% (3 d) 0.1% (120 d)Suchozebrysandy loam0.4% (3 d)0.2% (120 d)49275308 Loam 1.7% (14 d) 0.5% (120 d)835.4300Aerobicaquaticmetabolism49275312Water:sandyloam0.8% (62 d)0.3% (102 d)49275313Pond water:loamy sand0.9% (100 d)0.9% (100 d)Pondwater:loam1.4% (7 d)0.8% (120 d)Dihydroxytriazine(IN-F5475)IUPAC:6-Methyl-1,3,5-triazine2,4(lH,3H)-dioneFormula:C4H5N3O2MW:127.1 g/molSMILES:Cc1nc(nc(n1)O)O835.4100ASM49275308 Loam1.3% (30, 120 d)1.3% (120 d)835.4300AAM49275313Pond water:loamy sand1.5% (41 d)1.2% (100 d)AAR means “applied radioactivity”. MW means “molecular weight”. PRT means “parent”. NA means “not applicable”.

### Page 92 of 318 Flazasulfuron

Code Name

Chemical Name Chemical Structure

Flazasulfuron



### DPTU 1-(4,6-Dimethoxypyrimidin-2-yl)-1-(3- trifluoromethyl-2-pyridyl)-urea

(unique to flazasulfuron)



### DTPP 4,6-Dimethoxy-2-(3-trifluoromethyl-2- pyridylamino)pyrimidine

(unique to flazasulfuron)



### TPSA 3-(Trifluoromethyl)-2-pyridinesulphonamide

(unique to flazasulfuron)



### ADMP 2-Amino-4,6-dimethoxypyrimidine

A common degradate with other sulfonylurea herbicides 

### N

S

CF 3 O O

NH NH

O N N O

O CH 3

CH 3

N

CF 3 N

N N O

O CH 3

CH 3 O

NH 2



### N

NH

N N

CF 3 O

O CH 3

CH 3

N

CF 3 S NH 2 O

O

N

N H 2 N O

O C H 3

C H 3

### Page 93 of 318 ADMP 2-amino-4,6-dimethoxypyrimidine

2,3-GTF 3-trifluoromethyl-2-pyridylguanidine N

N H 2 N O

O CH 3

CH 3Page94of318ForamsulfuronCode Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)MAJORAEF130619Foramsulfuronamine4-amino-2-(N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-N,Ndimethylbenzamide4-amino-2-[3-(4,6-dimethoxypyrimidin-2-yl)ureidosulfonyl]-N,NdimethylbenamideFormula:C16H20N6O6SMW:424.43 g/molHydrolysis (pH 4@ 25 °C)45109324/Supplemental2.6 (10 d, pyrlabel)2.1 (10 d)Hydrolysis (pH 7@ 25 °C)45109324/Supplemental9.1 (30 d, phenyllabel)9.1 (30 d)Hydrolysis (pH 9@ 25 °C)45109324/Supplemental7.6 (30 d, phenyllabel)7.6 (30 d)Aerobic Soil45109714/acceptable10.4 (3 d) 0.3 (366 d)Aerobic Soil45109713/acceptable30.8(1 d) 0.6 (203 d)AnaerobicAquatic45109729/supplemental1.2 (58 d)total system<LOD (365 d)total systemAEF153745Foramsulfuronsulfonamide4-Formylamino-N,N-dimethyl-2-sulfamoyl-benzamideFormula:C10H13N3O4SMW:271.29g/molNHSNH2OONOOHydrolysis (pH 4@ 25 °C)45109324/Supplemental66.3 (10 d) 66.3 (10 d)Hydrolysis (pH 5@ 25 °C)45109324/Supplemental71.3(30d)71.3 (30 d)Hydrolysis (pH 7@ 25 °C)45109324/Supplemental3.3 (30d) 3.3 (30 d)Hydrolysis (pH 9@ 25 °C)45109324/Supplemental4.1 (30d) 4.1 (30 d)Page95of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)Aerobic Soil45109714/acceptable5.0 (0 d) 0.5 (366 d)Aerobic Soil45109713/acceptable7.8 (3 d) 0.6 (203 d)AnaerobicAquatic45109729/supplemental8.2 (112 d)total system<LOD (365 d)total systemAEF0929444,6-dimethoxypyrimidin-2-amine2-amino-4,6-dimethoxypyrimidineFormula:C6H9N3O2MW: 155.15 g/molHydrolysis (pH 4@ 25 °C)45109324/Supplemental79.7 (10 d) 79.7 (10 d)Hydrolysis (pH 5@ 25 °C)45109324/Supplemental83.3(30 d) 83.3 (30 d)Hydrolysis (pH 7@ 25 °C)45109324/Supplemental4.7 (30 d) 4.7 (30 d)Hydrolysis (pH 9@ 25 °C)45109324/Supplemental1.9 (30 d) 1.9 (30 d)Aerobic Soil45109714/acceptable17.8 (63 d) 5.3 (366 d)Aerobic Soil45109713/acceptable16.9 (56 d) 7.0 (203 d)TFD45109722/supplemental5.06μg/kg (4d) <LOQ (114)F0338795Formula:C16H18N6O7SMW:438.42 g/molNHSNHNHNNOONOOOOHOAnaerobicAquatic45109729/supplemental17.0(226 d) <LOD (365 d)UnknownsAerobic Aquatic45109728/supplemental28.6 (57 d)total system4.6 (57 d)*14.8 (365 d)total system3.5 (365 d)*AnaerobicAquatic45109729/supplemental53.4 (288 d)total system13.8 (112 d)*53.0 (365 d)total system9.0 (112 d)*Page96of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)Non-extractedResiduesAerobic Aquatic45109728/supplemental75.4 (211 d)total system40.4 (365 d)total systemAnaerobicAquatic45109729/supplemental26.0 (288 d)total system26.0 (365 d)total systemMINORAEF1480034-amino-N,N-dimethyl-2-sulfamoyl-benzamideFormula:C9H13N3O3SMW:243.28 g/molH2NSNH2ONOOHydrolysis (pH 4@ 25 °C)45109324/Supplemental5.6(10 d) 5.6 (10 d)Hydrolysis (pH 5@ 25 °C)45109324/Supplemental3.0 (30 d) 3.0 (30 d)Aerobic Soil45109714/acceptable2.2 (63 d) 0.8 (366 d)Aerobic Soil45109713/acceptable0.9 (10, 134 d) 0.4 (203 d)AEF00149406-formamido-1,2-benisothiasol3(2H)-one 1, 1-dioxideN-(1,1,3-Trioxo-2,3-dihydro-1H1l6-benzo[d]isothiazol-6-yl)-formamideFormula:C8H6N2O4SMW:226.21NHSNHOONOOHydrolysis (pH 4@ 25 °C)45109324/Supplemental7.9 (10 d) 7.9 (10 d)Hydrolysis (pH 5@ 25 °C)45109324/Supplemental9.7(30 d) 9.7 (30 d)AEF00010826-amino-1,1-dioxo-1,2-dihydro1l6-benzo[d]isothiazol-3-one6-amino-1,2-benzisothiasol3(2H)-one 1,1-dioxide,potassium saltFormula:C7H6N2O3SMW:198.20H2NSNHOOOHydrolysis (pH 4@ 25 °C)45109324/Supplemental1.1 (10 d) 1.1 (10 d)Page97of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)AEF099095(4,6-Dimethoxy-pyrimidin-2-yl)-ureaFormula:C7H10N4O3MW:198.18NH2NHNNOOOAerobic Soil45109713/acceptable0.8 (21 d) <LOD (203 d)Boldfont indicates the highest percentage observed for a given transformation product.MW: molecular weight* Largest single unknown; it is unclear if the residues cited are the same.

### Page 98 of 318 Halosulfuron-methyl

Chemical structures of halosulfuron-methyl and selected environmental degradates

Halosulfuron-methyl CHEMICAL NAME:methyl 5-{[(dimetho xy-2-pyrimidinyl) amino] carbonyla minosulfonyl -3-chloro -1-methyl1-H- pyrazole-4-carboxylate

Halosulfuron rearrangement ester or CP-151790 or PZ-SP-2

CHEMICAL NAME:3-Chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole4-carboxylic acid, methyl ester

OR 1H-Pyrazole-4-carboxylic acid, 3-chloro-5- [(4,6-dime thoxy-2-pyrimidinyl)amino] -1-methyl, methyl ester

OR Methyl 3-Chloro-5-(4,6-dimetho xypyrimidin-2-ylamino)- 1-methylpyrazole-4-carboxylate

Halosulfuron aminopyrimidine or CP 17477 CHEMICAL NAME:4,6-Dimethoxy-2-pyrimidinamine

Halosulfuron guanidine or PZ-SP-12 IH-Pyrazole-4-carboxylic acid. S-[([[(aminoi minomethyl)amino]carbony l]amino]sulfonyl]- 3-chloro-l-melhyl

### Page 99 of 318 Halosulfuron acid or CP-147921

CHEMICAL NAME: 3-Chloro-5-[[[[(4,6-dimethoxy-2-pyrimidinyl) amino] carbonyl]amino] sulfonyl ]-l-methyl-1H-pyrazole-4- carboxylic acid

3-Chlorosulfonamide acid (pyrazole) or CP-147924 or PZ-SP-8

CHEMICAL NAME: 5-(Aminosulfonyl)-3-chloro-l-meth yl-1H-pyrazole-4-carboxylic acid

OR IH-Pyrazole-4-carboxylic acid. 5-(a minosulfonyl)-3-chloro-l-melhyl

Desmethyl halosulfuron or CP 147922

CHEMICAL NAME: 3-Chloro-5-[[[[(4-hydroxy-6-methoxy-2-pyrimidinyl) amino] carbonyl] amino] sulfonyl]-1-methyl-1H-pyrazole-4-carboxy!ic acid, methyl ester

3-Chlorosulfonamide ester or CP 147925

CHEMICAL NAME: 5-(Aminosulfonyl)-3-chloro-l-meth yl-1H-pyrazole-4-carboxylic acid, methyl ester

OR IH-Pyrazole-4-carboxylic acid. S-(aminosulf onyl)-3-chloro-l-melhyl-. methyl ester 

### S NH 2 

### O

O

N N

O O

Cl

### Page 100 of 318 Imazosulfuron

Table 6. Major and Minor Degradates of Imazosulfuron

Name of Degradate

And

Structure IUPAC Name Maximum

Detected (%) Comments

Major degradates

HMS 1-(2-chloroimidazo[1,2- D ]pyridin-3- ylsulfonyl)-3-(4-hydroxy-6- methoxypyrimidin-2-yl)urea 20.9 Detected under both imidazolyl (IM) and pyrimidinyl (PM) labels

IPSN 2-Chloroimidazo[1,2-a]pyridin-3-

sulfonamide. 90.7 IM label at pH 4.0

IOHA 2-(2-imino-1,2-dihydropyridin-1-yl)oxalic

acid 20.4 IM label

ADPM 2-amino-4,6-dimethoxypyrimidine 91.2 PM label at pH 4.0

UPDM 4,6-dimethoxy-2-ureidopyrimidine 11.2 PM label

SDPM (4,6-dimethoxypyridine-2- yl)aminocarbonylsufamic acid 13.9 PM label

CO 2 Carbon dioxide 53.3 PM label N N Cl

S

O O

N

H N

O

H N N

O O H

CH 3

N N Cl

S

O O

N

H H

N NH O

O H

O

H

N

N N

O O CH 3

CH 3 H

N

H N

O

H N N

O O CH 3

CH 3 H

S

O O

N

H N

O

H N N

O O CH 3

CH 3 O H



### C O O

### Page 101 of 318 Table 6. Major and Minor Degradates of Imazosulfuron

Name of Degradate

And

Structure IUPAC Name Maximum

Detected (%) Comments

Minor degradates

IP 2-Chloroimidazo[1,2- D ]pyridine 3.2 IM label at pH 4.0

IPSA 2-chloroimidazo[1,2- D ]pyridin-3-yl sulfonic

acid 5.8 IM label

CDPM 2-cyano-4,6-dimethoxypyrimidine 5.3 PM label

AHMP 2-Amino-4-hydroxy-6-methoxypyrimidine 4.7 PM label

ACIS N- ({[Amino(imino)methyl] amino}carbonyl)- 2-chloroimidazo[1 ,2-a]pyridine-3-

sulfonamide 9.4 IM Label N N Cl

N N Cl

S

O O

OH

N

N N

O O CH 3

CH 3 H N

N

N N

O O H

CH 3 H

H

N N Cl

S

O O

N

H N

O

H NH 2 NHPage102of318IodosulfuronCode Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)MAJORAE F075736Metsulfuron methyl;methyl 2-[3-(4-methoxy-6-methyl1,3,5-triazin-2-y1)ureidosulfonyl]benzoateC14H15N5O6SMol. Wt.: 381.3638CO2CH3SO2HNHNON NNCH3OCH3Aerobic Soil4510893455.31 DAT2.9120 d4510893570.114 DAT25.5120 d4510893647.714 DAT10120 d4510900158.611 DAT4.4120 dAerobic Aquatic 4510902167.843 DAT1.4365 dAnaerobicAquatic451090231.55 DAT<LOD366 dAE F161778methyl 2-[3-(4-hydroxy6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]benzoateC13H13N5O6SMol. Wt.: 367.3372CO2CH3SO2HNHNON NNCH3OHAerobic Soil4510893412.228 DAT3.5120 d451089355.863 DAT3.5120 d4510893613.742 DAT9.3120 d451090018.528 DAT3.3120 dAE 00149662-[3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]benzoic acidC13H13N5O6SCO2HSO2HNHNON NNCH3OCH3Aerobic Aquatic 4510902115.591 DATn.d.365 dAnaerobicAquatic4510902333.2113 DAT<LOD366 dPage103of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)Mol. Wt.: 367.3372AE 0014965Dimethoxy-metsulfuronfree acid2-[3-(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)ureidosulfonyl]benzoic acidC12H11N5O6SMol. Wt.: 353.3106CO2HSO2HNHNON NNCH3OHAnaerobicAquatic4510902316.0113 DAT2.5366 dAE F1457404-iodo-2-[3-(4-methoxy6-methyl-1,3,5-~idosulfonylbenzoic acidC14H14IN5O6SMol. Wt.: 507.2603CO2CH3ISO2HNHNON NNCH3OCH3Aerobic Soil451089343.211 DAT1.3120 d451089351.04 DATn.d.120 d451089361.442 DAT0.7120 d451090014.464 DAT3.6120 dAnaerobicAquatic4510902350.628 DAT<LOD366 d4510893618.8120 DAT18.8120 d4510900133.4120 DAT33.4120 dAerobic Aquatic 4510902127.5365 DAT13.7365 dAE0002166Methyl 4-hydroxy-2-[3-(4-methoxy-6-methyl1,3,5-triazin-2-yl)ureido]benzoateC14H15N5O6SMol. Wt.: 381.3638CO2CH3HOSO2HNHNON NNCH3OCH3Soil Photolysis 4510900321.4144 HAT21.4144 hPage104of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)AE0 0348554-hydroxy-6-methyl1,3,5-triazine-2-yl)ureaC5H7N5O2Mol. Wt.: 169.1414H2NHNON NNCH3OHAerobic Aquatic 4510902124.2182 DAT16.5365 dAE 0000119(4-methoxy-6-methyl1,3,5-triazin-2-yl)ureaC6H9N5O2Mol. Wt.: 183.1680H2NHNON NNCH3OCH3Aerobic Soil 451089344.228 DAT4.1120 dAerobic Aquatic451089365.4120 DAT5.4120 d451090014.064 DAT3.9120 d4510902124.9120 DAT12.4365 dAEF159737saccharin1,2-benzisothiazol3(2H)-one 1,1-dioxideC7H5NO3SMol. Wt.: 183.1845SO2NHOAnaerobicAquatic451090239.7182 DAT<LOD366 dUnknownsSoil Photolysis 451090039.5 (combined)327 HAT6.9393 hAerobic Soil451089346.263 DAT3.3120 d451089357.2 (combined)120 DAT1.2120 d451090019.8 (single)120 DAT9.8120 dNon-extractedResiduesAerobic Soil4510893439.3120 DAT39.3(120 d)451089359.391 DAT9.0120 d4510893633.8120 DAT33.8120 d4510900135.7120 DAT135.7120 dAerobic Aquatic 4510902130.3365 DAT30.3365 dPage105of318Code Name/SynonymChemical NameChemical StructureStudy TypeRef.(MRID)Maximum%AR (day)Final %AR(studylength)MINORAE F143133Iodo saccharin6-iodo-1,2-benzisothiazol-3(2H)-one 1, 1-dioxideC7H4INO3SMol. Wt.: 309.0810SO2NHOIAnaerobicAquatic451090232.23 DAT<LOD366 dAE FI45741methyl 2-[3-(4-hydroxy6-methyl-1,3,5-triazin-2-yl)105reidosulfonyl4-iodobenzoateC13H12IN5O6SMol. Wt.: 493.2337CO2CH3ISO2HNHNON NNCH3OHAerobic Soil451089343.24, 7 DAT1.6120 d451089353.40 DATn.d.120 d451089364.914 DAT2.2120 d451090014.364 DAT3.8120 dBoldfont indicates the highest percentage observed for a given transformation product.MW: molecular weightAR: Applied radioactivityn.d. not detected <LOD

### Page 106 of 318 Mesosulfuron-methyl

Mesosulfuron-methyl Degradates



### Parameter Value 

### Reference Comments

Bridge-intact Metabolites of Mesosulfuron-methyl (Unique to Mesosulfuron-methyl)

Company Code AE F154851 MRID 45386425 Mesosulfu r

Chemical Name 2-[3-(4,6-dimethoxypyrimidine-2- yl)ureidosulfonyl]-4- methanesulfonamidomethyl benzoic

acid MRID 45386425

Empirical Formula 

### C 16 

### H 19 

### N 5 

### O 9 

### S 2 EPI 4.1

SMILES O=C(Nc1nc(OC)cc(OC)n1)NS(=O)( =O)c2cc(ccc2C(=O)O)CNS(=O)(=O )C EPI 4.1

CAS Number 400852-66-6

Molecular mass 489.48 EPI 4.1

Structure http://www.chemsp

ider.com/Structure Search.aspx

Koc (mL/g) 119 (Minnesota clay loam) 66 (Hattersheim silt loam) 50 (Münster sandy loam) MRID 45386433 (Acceptable)

Company Code AE F160459 MRID 45386427

MRID 45386429

Chemical Name Methyl 2-[3-(4-hydroxy-6- methoxypyrimidine-2- yl)ureidosulfonyl]-4- methanesulfonamido-methyl

benzoate MRID 45386427

MRID 45386429

Empirical Formula 

### C 16 

### H 19 

### N 5 

### O 9 

### S 2 EPI 4.1

SMILES C(=O)(c1c(S(=O)(=O)NC(=O)Nc2n c(O)cc(OC)n2)cc(CNS(C)(=O)=O)c c1)OC EPI 4.1

Molecular mass 489.48 EPI 4.1

### Page 107 of 318 Mesosulfuron-methyl Degradates



### Parameter Value 

### Reference Comments

Structure http://www.chemsp

ider.com/Structure Search.aspx

Company Code AE F160460 MRID 45386429

Chemical Name 2-[3-(4-hydroxy-6- methoxypyrimidin-2-yl) ureidosulfonyl]-4- methanesulfonamidomethyl-benzoic

acid MRID 45386429

Empirical Formula 

### C 15 

### H 17 

### N 5 

### O 9 

### S 2 EPI 4.1

SMILES C(=O)(O)c1c(S(=O)(=O)NC(=O)Nc 2nc(O)cc(OC)n2)cc(CNS(C)(=O)=O )cc1 EPI 4.1

Molecular mass 475.45 EPI 4.1

Structure http://www.chemsp

ider.com/Structure Search.aspx

Phenyl Ring Bridge-cleavage Metabolites of Mesosulfuron-methyl (Unique to Mesosulfuron-methyl)

Company Code AE F140584 MRID 45386418

Chemical Name Methyl 4- methanesulfonamidomethyl-2- sulfamoylbenzoate MRID 45386418

Empirical Formula C 10 H 14 N 2 O 6 S 2 EPI 4.1

SMILES C(=O)(c1c(S(N)(=O)=O)cc(CNS(C)( =O)=O)cc1)OC EPI 4.1

Molecular mass 322.35 EPI 4.1

### Page 108 of 318 Mesosulfuron-methyl Degradates



### Parameter Value 

### Reference Comments

Structure http://www.chemsp

ider.com/Structure Search.aspx

Company Code AE F147447 MRID 45386418

Chemical Name 6-Methanesulfonamidomethyl- 1,2- benzisothiazol-3(2H)-one 1,l dioxide MRID 45386418

Empirical Formula C 9 H 10 N 2 O 5 S 2 EPI 4.1

SMILES C1(=O)c2c(cc(CNS(C)(=O)=O)cc2) S(=O)(=O)N1 EPI 4.1

Molecular mass 290.31 EPI 4.1

Structure http://www.chemsp

ider.com/Structure Search.aspx

Pyrimidine Ring Bridge-cleavage Metabolites of Mesosulfuron-methyl (Common to Other Sulfonylurea Herbicides)

Company Code AE F099095 MRID 45386434

Chemical Name (CAS) 4,6-dimethoxypyrimidin-2-yl-urea MRID 45386434

Empirical Formula C 7 H 10 N 4 O 3 EPI 4.1

SMILES c1(OC)cc(OC)nc(NC(N)=O)n1 EPI 4.1

Molecular mass 198.18 EPI 4.1

Structure http://www.chemsp

ider.com/Structure Search.aspx

Koc (mL/g) 3856 (Minnesota clay loam) 365 (Hattersheim silt loam) 206 (Münster sandy loam) MRID 45386434 (Acceptable)

Company Code AE F119094

Chemical Name (CAS) 4-Hydroxy-6-methoxypyrimidin-2- yl-urea

Empirical Formula C 6 H 8 N 4 O 3 EPI 4.1

SMILES c1(O)cc(OC)nc(NC(N)=O)n1 EPI 4.1

Molecular mass 184.16 EPI 4.1

### Page 109 of 318 Mesosulfuron-methyl Degradates



### Parameter Value 

### Reference Comments

Structure http://www.chemsp

ider.com/Structure Search.aspx

Company Code AE F092944 MRID 45386418

MRID 45386425

Chemical Name (CAS) 2-Amino-4,6-dimethoxypyrimidine MRID 45386418

MRID 45386425

Empirical Formula C 6 H 9 N 3 O 2 EPI 4.1

SMILES c1(OC)cc(OC)nc(N)n1 EPI 4.1

CAS Number 36315-01-2 CSID:106290

Molecular mass 155.16 EPI 4.1

Structure http://www.chemsp

ider.com/Structure Search.aspx

1 http://www.epa.gov/oppt/expo sure/pubs/episuite.htm

### Page 110 of 318 Metsulfuron-methyl

### Page 111 of 318Page112of318NicosulfuronDegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsHydrolysis (pH 5 only; Nicosulfuron stable at pH 7 and pH 9) – MRID No. 40924220IN-V9367or Pyridine Sulfonamide2-(aminosulfonyl)-N,Ndimethyl-3-pyridinecarboxamide31.4% at 30daysDetected with[Pyridine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 30days.IN-J0290or Pyrimidine Amine4,6-dimethoxy-2-pyrimidinamine32.1% at 30daysDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 30days.DPX-V9360 Ipso Precursor2-[(Aminocarbcnyl)(4,6-dimethoxy-pyrimidin-2-yl)-amino]-N,N-dimethyl-3-pyridinecarboxamide6.05% at 30daysDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 30days.Page113of318DegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsAerobic Aquatic Metabolism (MRID No. 4854304)IN-377402-[[(3,4-dihydro-6-methoxy-4-oxopyrimidin-2-yl]aminocarbonyl]aminosulfonyl]-N, Ndimethyl-3-pyridinecarboxamide14.55% at102 daysDetected with[Pyridine-2-14C]NicosulfuronRadiolabel.Studies wereterminated at 102days.IN-HYY21 or AUSN2-[[[[(Aminoiminomethyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide3.3% at 102daysDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Studies wereterminated at 102days.IN-777992-[(Aminocarbonyl) [4-methoxy-6-(methyldioxy)-2-pyrimidinyl] amino]-N, N -dimethyl-3-pyridinecarboxamide1.5% at 102daysDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Studies wereterminated at 102days.Page114of318DegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsIN-V9367or Pyridine Sulfonamide2-(aminosulfonyl)-N,Ndimethyl-3-pyridinecarboxamide2.65% at 102daysDetected with[Pyridine-2-14C]NicosulfuronRadiolabel.Studies wereterminated at 102days.Aerobic Soil Metabolism (MRID Nos. 41082622 and 46240901)IN-HYY21 or AUSN2-[[[[(Aminoiminomethyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide9.4% at 120days inalkaline soilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 120days.IN-V9367or Pyridine Sulfonamide2-(aminosulfonyl)-N,Ndimethyl-3-pyridinecarboxamide47% at 180days in acidicsoil9.1%at 120days inalkaline soilDetected with[Pyridine-2-14C]Radiolabel.Study in acidicsoil ended at 240days; in alkalinesoil ended at 120days.Page115of318DegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsIN-J0290or Pyrimidine Amine4,6-dimethoxy-2-pyrimidinamine42% at 180days in acidicsoilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study in acidicsoil wasterminated at 240days.IN-GDC422-[[[(Aminocarbonyl)amino]carbonylamino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide2.2% at 90and 120 daysin alkalinesoilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study in alkalinesoil wasterminated at 120days.IN-377402-[[(3,4-dihydro-6-methoxy-4-oxopyrimidin-2-yl]aminocarbonyl]aminosulfonyl]-N, Ndimethyl-3-pyridinecarboxamide3.1% at 14days inalkaline soilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study in alkalinesoils wasterminated at 120days.Page116of318DegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsIN-777992-[(Aminocarbonyl) [4-methoxy-6-(methyldioxy)-2-pyrimidinyl] amino]-N, N -dimethyl-3-pyridinecarboxamide2.75% at 21days inalkaline soilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 120days.Anaerobic Soil Metabolism (MRID No. 41082623)IN-V9367or Pyridine Sulfonamide2-(aminosulfonyl)-N,Ndimethyl-3-pyridinecarboxamide29.5% at 90days in acidicsoilDetected with[Pyridine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 90daysIN-J0290or Pyrimidine Amine4,6-dimethoxy-2-pyrimidinamine25% at 61days in acidicsoilDetected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 90daysPage117of318DegradateIdentityStructureMax% ofAppliedand DaysPostApplicationCommentsTerrestrial Field Dissipation (MRID No. 43483901)IN-V9367or Pyridine Sulfonamide2-(aminosulfonyl)-N,Ndimethyl-3-pyridinecarboxamide15.85% in 0 -6 inch soildepth at 61days inIllinois SiltyClay LoamSoil (acidic)5.15% in 0 -6inch soildepth at 121days inCaliforniaSandy LoamSoil(alkaline)Detected with[Pyridine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 545daysIN-J0290or Pyrimidine Amine4,6-dimethoxy-2-pyrimidinamine13.4% in 0 -6 inch soildepth at 61days inIllinois SiltyClay LoamSoil (acidic)Detected with[Pyrimidine-2-14C]NicosulfuronRadiolabel.Study wasterminated at 545days

### Page 118 of 318 Orthosulfamuron

Code Name/ Synonym/

Chemical Name/ Formula/MW/ SMILES Chemical Structure

Orthosulfamuron, IR5878, S3, H3

IUPAC: 1-(4,6-Dimethoxypyrimidin-2-yl)-3-[2- (dimethylcarbamoyl)phenylsulfamoyl]urea.

CAS: 2-[[[[[(4,6-Dimethoxy-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]amino]- N,N-dimethylbenzamide

CAS No.: 213464-77-8

Formula: C 16 H 2 ON 6 O 6 S

MW: 424.4 g/mol

SMILES: CN(C(=O)c1ccccc1NS(=O)(=O)NC(=O)Nc1nc(cc(n1)O C)OC)C

DBS acid, IR7863, S1, H1

IUPAC: (2-Dimethylcarbamoyl phenyl)sulfamic acid

CAS: Sodium (2-dimethylcarba moylphenyl)sulfamate

Other: 2-Sulfamino-N,N-dimethylbenzamide

CAS No.:

Formula: C 9 H 12 N 2 SO 4 MW: 244.28g/mol

SMILES: CN(C)C(=O)c1ccccc1NS(=O)(=O)O

DB amine, S4, H4

IUPAC: (2-2-Amino-N,N-dimethylbenzamide

Formula: C 9 H 12 N 2 O

MW: 164.21 g/mol

SMILES: CN(C)C(=O)c1ccccc1N

DOP amine, S13, H6

IUPAC: 4,6-Dimethoxypyrimidin-2-yl amine 2-Amino-4,6-dimethoxypyrimidine

Formula: C 7 H 10 N 4 O 3 MW: 198.21

SMILES: COc1cc(OC)nc(N)n1

DOP urea, IR7825, S12, H5

IUPAC: N-(4,6-Dimethoxypyrimidin-2-yl)-urea

CAS : 4,6-Dimethoxy-2-pyrimidinyl urea

Formula: C 6 H 9 N 3 O 2 MW: 155.16 N

O NH S O
O

NH O

NH

N N O

O



### N

NH S O

O O

OH

N

NH 2 O

N 2 H N N O

O

N 2 H NH N N O

O O

### Page 119 of 318 Code Name/ Synonym/

Chemical Name/ Formula/MW/ SMILES Chemical Structure

SMILES: COc1cc(OC)nc(NC(N)=O)n1

DBS amide, S2, H2

Other: 2-Sulfamoylamino-N,N-dimethylbenzamide

Formula: C 9 H 13 N 3 SO 3

MW: 243.28 g/mole

SMILES: CN(C)C(=O)c1ccccc1CS(N)(=O)=O

O-desmethyl IR5878, O-desm ethyl orthosulfamuron, IR8181, S9

IUPAC: 1-(4-Hydroxy-6-methoxypyrimidin-2-yl)-3-[2- (2-dimethylcarbamoyl)phenylsulfamoyl]urea

CAS: 1-[2(Dimethylcarbamoyl)phenylsulfamyl]-3-(4- hydroxy-6-methoxypyrimidin-2-yl)urea

SMILES: COc2cc(O)nc(NC(=O)NS(=O)(=O)Nc1ccccc1C(=O)N(C )C)n2

S11 (multiple unresolved compounds)

S5 (multiple unresolved compounds)

o-desmethyl DOP urea, S15

MW: 184.16

SMILES: COc1cc(O)nc(NC(N)=O)n1

S6

S8

IR8181

S16

S7

Abbreviations: nd = not detected ; AR =applied radioactivity; MW =molecular weight. N

NH S NH 2 O

O O

N

NH S NH NH N N OH

O O O

O O

N H O

H 2 N N

N O OH

### Page 120 of 318 Common Name or

Code Name Study Type MRID Max %AR or Conc. (sampling interval) Final %AR or Conc. (sampling interval) Descriptive Information

for Value

Orthosulfamuron, IR5878, S3, H3

Hydrolysis 46219015 33 ( 37 days) pH 7, 25 o C

56 (176 days) pH 9, 25 o C

nd (5 days) pH 4, 50 o C

18 (5 days) pH 7, 50 o C

72 (5 days) pH 9, 50 o C

Hydrolysis 46219016 15 (1 hr) 1 hr, pH 4, 50 o C

27 (52 hrs) 52 hrs, pH 7, 50 o C

33 (13 days) 13 days, pH 9, 50 o C
Aqueous photolysis 46588509 95 (7 days)

Anaerobic Aquatic 46578967 22 (180 days) AR pyr

19 (180 days) AR phe label

7 (180 days) CA pyr label

Aquatic Field Dissipation 46578985 0.083 mg/kg (0day) nd (123 day) AR soil

0.171 mg/kg (3 day) <0.005 mg/kg (60 day) AR sediment

0.017 mg/L (3 day) <0.005 (22 day) AR water

0.103 mg/kg (0 day) <0.005 mg/kg (194 day) CA Soil

0.056 mg/kg (3 day) nd (60 day) CA sediment

DBS acid, IR7863, S1, H1

Hydrolysis 46219015 58 ( 37 days) 58 ( 37 days) pH 7, 25 o C
23 (176 days) 23 (176 days) pH 9, 25 o C
86 (5 days) 86 (5 days) pH 4, 50 o C
66 (5 days) 66 (5 days) pH 7, 50 o C
12 (5 days) 12 (5 days) pH 9, 50 o C

Aerobic Aquatic 46219017 54 (90 day) 54 (90 days) AR phe label
61 (61 days) 61 (61 days) CA phe label

Anaerobic aquatic 46578967 12 (100 days) 9 (180 days) AR phe label
39 (150 days) 39 (150 days) CA pyr label

Aquatic field dissipation 46578985 0.047 mg/kg(7 days) nd (550 days) AR soil
0.065 mg/kg (7 days) nd (60 days) AR sediment
0.011 mg/L (15 days) <0.005 mg/L (60 days) AR water
<0.02 mg/kg (7 days) nd (553 days) CA soil
<0.02 mg/kg (7 days) nd (60 days) CA sediment
<0.005 mg/L (15 days) nd (60 days) CA water

DB amine, S4, H4

Hydrolysis 46219015 2 (37 days) 2 (37 days) pH 7, 25 o C
13 (176 days) 13 (176 days) pH 9, 25 o C
13 (5 days) 13 (5 days) pH 4, 50 o C
11 (5 days) 11 (5 days) pH 7, 50 o C
6 (5 days) 6 (5 days) pH 9, 50 o C

Aerobic aquatic 46219017 <1 (90 days) <1 (90 days) AR
1 (90 days) 1 (90 days) CA

Anaerobic aquatic 46578967 6 (42 days) 5 (42 days) AR phe label
6 (100 days) 4 (150 days) CA phe label

### Page 121 of 318 Common Name or

Code Name Study Type MRID Max %AR or Conc. (sampling interval) Final %AR or Conc. (sampling interval) Descriptive Information

for Value

DOP amine, S13,

H6 Hydrolysis 46219016 4 (1hr) 4 (1hr, pH 4, 50 o C) pH 4, 50 o C
11 (52 hrs) 11 (52 hrs) pH 7, 50 o C
53 (13 days) 53 (13 days) pH 9, 50 o C

Aerobic aquatic 46219017 1 (90 days) 1 (90 days) AR sediment
1 (30 days) 1 (90 days) CA sediment

Anaerobic Aquatic 46578967 <1 (100 days) <1 (180 days) AR pyr label

DOP urea, IR7825, S12, H5 Hydrolysis 46219016 78 (1hr) 78 (1hr) pH 4, 50 o C
60 (52 hrs) 60 (52 hrs) pH 7, 50 o C
13 (13 days) 13 (13 days) pH 9, 50 o C

Aerobic Aquatic 46219017 47 (90 days) 47 (90 days) AR pyr label
40 (30 days) 36 (61 days) CA pyr label

Anaerobic Aquatic 46578967 12 (42 days) 3 (180 days) AR pyr label
19 (59 days) 16 (150 days) CA pyr label

Aquatic Field Dissipation 46578985 0.07 mg/kg (186 day) 0.024 mg/kg (123 day) AR soil
0.147 mg/kg (15 day) 0.041 mg/kg (60 day) AR sediment
<0.005 mg./L (60 days) <0.005 mg./L (60 days) AR water
0.089 (194 day) 0.033 mg/kg (553 day) CA soil
0.162 mg/kg (7 day) 0.023 mg/kg (60 day) CA sediment
<0.005 mg/L (30 days) nd (60 days) CA water

DBS amide, S2,

H2

Hydrolysis 46219015 7 ( 37 days) 7 ( 37 days) pH 7, 25 o C
8 (176 days) 8 (176 days) pH 9, 25 o C
9 (0.13 days) 1 (0.04 days) pH 4, 50 o C
8 (2 days) 5 (5 days) pH 7, 50 o C
10 (5 days) 10 (5 days) pH 9, 50 o C

Anaerobic aquatic 46578967 4 (180 days) 4 (180 days) AR phe label

4 (150 days) 4 (150 days) CA phe label

Aerobic aquatic 46219017 4 (90 days) 4 (90 days) AR phe label
4 (61 days) 4 (61 days) CA phe label
O-desmethylIR5878, Odesmethyl orthosulfamuron, IR8181, S9 Aerobic aquatic 46219017 9 (90 days) 9 (90 days) AR pyr label
7 (90 days) 7 (90 days) AR phe label
7 (30 days) 6 (90 days) CA pyr label
6 (44 days) 6 (61 days) CA phe label

Anaerobic aquatic 46578967 19 (100 days) 16 (180 days) AR phe label

17 (180 days) 17 (180 days) AR pyr label
12 (59 days) 4 (150 days) CA pyr label
13 (35 days) 4 (150 days) CA phe label
S11 (multiple

unresolved compounds) Aerobic aquatic 46219017 3 (90 days) 3 (90 days) AR
6 (90 days) 6 (90 days) CA

Anaerobic Aquatic 46578967 23 (180 days) 23.18 (180 days) AR pyr label

Aerobic aquatic 46219017 4 (90 days) 4 (90 days) AR
4 (90 days) 4 (90 days) CA

### Page 122 of 318 Common Name or

Code Name Study Type MRID Max %AR or Conc. (sampling interval) Final %AR or Conc. (sampling interval) Descriptive Information

for Value

S5 (multiple

unresolved compounds) Anaerobic aquatic 46578967 22 (180 days) 22 (180 days) AR phe label

16 (100 daysphe) 15, (150 days) CA phe label

o-desmethyl DOP urea, S15 Aerobic aquatic 46219017 <1 (90 days) <1 (90 days) AR

4 (44 days) 3 (61 days) CA

Anaerobic aquatic 46578967 3 (180 days, AR pyr) 3 (180 days, AR pyr)

S6 Aerobic aquatic 46219017 <1 (7 days) 0.0 (90 days) AR

nd nd CA

S8 Aerobic aquatic 46219017 <1 (90 days) <1 (90 days) AR

nd nd CA

Anaerobic aquatic 46578967 2 (180 days) 2 (180 days) AR phe label
2 (100 days) 2 (150 days) CA phe label
IR8181 Aquatic field dissipation 46578985 nd nd CA or AR

S16 Anaerobic aquatic 46578967 <1 (180 days) <1 (180 days) AR pyr label
1 (0 days) <1 (180 days) AR phe label
1 (0 days) < LOD (150 days) CA phe label

S7 Anaerobic aquatic 46578967 <1 (15 days) < LOD (180 days) AR phe label
<1 (15 days) <LOD (150 days) CA phe label Abbreviations: %AR=percent applied radio activity present as the iden tified compound; Conc.=con centration measured in field study; phe = phenyl ring radiolab eled; pyrimidinyl ring radiolabeled; CA=C alifornia; AR=Arkansas; LOD=limit of

detection



### Primisulfuron-methyl

### Page 123 of 318 CGA171683

### Page 124 of 318 Prosulfuron

Code Name/ Synonym/

Chemical Name/ Formula/MW/ SMILES Chemical Structure

Prosulfuron, CGA-152005

IUPAC: 1-(4-methoxy-6-methyl- 1,3,5-triazin-2-yl)-3- [2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea

CAS: N-[[(4-methoxy-6-met hyl-1,3,5-triazin-2- yl)amino]carbonyl]-2-(3,3,3-trifluoropropyl)-

benzenesulfonamide

CAS No.: 094125-34-5

Formula: C 15 H 16 F 3 N 5 O 4 S

MW: 419.38

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C2=NC(=NC(=N2)OC([H])([H])[H])C)[H])[H]

CGA-159902

IUPAC: 2-(3,3,3-trifluoropropyl)phenyl sulfonamide

CAS: 2-(3,3,3-trifluoropropyl)-benzenesulfonamide

CAS No.:

Formula: C 9 H 10 F 3 N 1 O 2 S 1 MW: 253.24

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N([H])[H]

### Page 125 of 318 CGA-150829

IUPAC: 4-methoxy-6-methyl-1,3,5-triazin-2-amine

Formula: C 5 H 8 N 4 O 1 MW: 140.15

SMILES: N(C1=NC(=NC(=N1)C)OC)([H])[H]

CGA-300406

IUPAC: N-[[(4-hydroxy-6-methyl-1,3,5-triazin-2- yl)amino]carbonyl]-2-(3,3,3-trifluoropropyl)-

benzenesulfonamide

CAS: N-[[(1,4-dihydro-6-methyl-4-oxo-1,3,5-triazin-2- yl)amino]carbonyl]-2-(3,3,3- trifluoropropyl)benzenesulfonamide]

Other: O-desmethyl triasulfuron

Formula: C 14 H 14 F 3 N 5 O 4 S 1 MW: 405.35

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C2=NC(=NC(=N2)C)O[H])[H])[H]

CGA-325025

CAS : N-[[(4-amino-6-methyl-1,3,5-triazin-2-yl)- amino]carbonyl]-2-(3,3,3-trifluoropropyl)-

benzenefulfonamide

Other: Desmethoxyamino CGA-152005

Formula: C 14 H 15 F 3 N 6 O 3 S 1 MW: 404.37

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)NC(=O)NC2 =NC(=NC(=N2)N([H])[H])C

CGA-325028

CAS: N- [[[[(aminocarbonyl)amino]carbonyl]amino]carbonyl-2- (3,3,3-trifluoropropyl)

Formula: C 12 H 13 F 3 N 4 O 5 S 1

MW: 382.32

SMILES:
C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C(=O)N(C(=O)N([H])[H])[H])[H])[H]

### Page 126 of 318 CGA-325026

CAS: N-[[aminocarbonyl)am ino]carbonyl]-2-(3,3,3- trifluoropropyl)

Formula: C 11 H 12 F 3 N 3 O 4 S 1

MW: 339.29

SMILES:
C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C(=O)N([H])[H])[H])[H]

CGA-325027

CAS: N-(aminocarbonyl)-2-(3,3,3-trifluoropropyl)

MW: 296.27

Formula: C 10 H 11 F 3 N 2 O 3 S 1

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N([ H])[H])[H]

G-28533

CAS: 6-methyl-1,3,5-triazine-2,4(1H,3H)-dione

MW: 127.10

Formula: C 4 H 5 N 3 O 2 SMILES: C1(=NC(=NC(=N1)C)O[H])O[H] MOL

FOR:

NANC-CGA-159902

CAS: N-[[aminocarbonyl)amino]carbonyl]-N-acetyl-2- (3,3,3-trifluoropropyl)

MW: 338.30

Formula: C 12 H 13 F 3 N 2 O 4 S 1 SMILES: C1=CC=CC(=C1CC(F)(F)F)S(=O)(=O)N(C(N(C(=O)N ([H])[H])[H])=O)C(=O)C

### Page 127 of 318 CGA-188838

CAS: 4-amino-6-methyl-1,3,5-triazin-2(1H)-one

MW: 126.12

Formula: C 4 H 6 N 4 O 1 SMILES : N(C1=NC(=NC(=N1)C)O[H])([H])[H]

CGA-325030

CAS: N-[[[[[[[[2-(3,3,3- trifluoropropyl)phenyl]su lfonyl]amino]carbonyl]amino] -carbonyl]amino]carbonyl]acetamide

Other: Polyimide Acetate

MW: 424.35

Formula: C 14 H 15 F 3 N 4 O 6 S 1 SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C(=O)N(C(=O)N(C(C)=O)[H])[H])[H])[H]

CGA-273437

CAS: N-[[[4-hydroxymethoxymethyl)-6-methoxy-1,3,5- triazin-2-yl)amino]carbonyl] -2-(3,3,3-trifluoropropyl)

MW: 435.38

Formula: C 15 H 16 F 3 N 5 O 5 S 1

SMILES: C(F)(F)(F)CCC1=C(C=CC=C1)S(=O)(=O)N(C(=O)N( C2=NC(=NC(=N2)C(O[H])([H])[H])OC)[H])[H]

MW =molecular weight.

Transformation

Product Study Type MRID Maximum %AR (day) Final %AR (study length)

CGA-150829 Hydrolysis 42685246

(triazine) 46.1 (30, pH 5, 25 o C)

0.8 (15, pH 7, 25 o C)

0.5 (30, pH 9, 25 o C) 46.1 (30, pH 5, 25 o C)

0.7 (30, pH 7, 25 o C)

0.5 (30, pH 9, 25 o C)

Photodegradation

in water 42685248

(triazine) 0.7 (30, pH 9, 25 o C, dark)

2.5 (30, pH 9, 25 o C, irradiated) 0.7 (30, pH 9, 25 o C, dark)

2.5 (30, pH 9, 25 o C, irradiated)

Photodegradation

in soil 43159328

(triazine) 4.4 (30, pH 7.2, 23.5 o C, dark)

5.2 (30, pH 7.2, 23.2 o C, irradiated) 4.4 (30, pH 7.2, 23.5 o C, dark)

5.2 (30, pH 7.2, 23.2 o C, irradiated)

### Page 128 of 318 Transformation

Product Study Type MRID Maximum %AR (day) Final %AR (study length)

Aerobic soil 42685250 (triazine) 11.9 (366) 11.9 (366)

43387712

(triazine) 31.0 (366) 31.0 (366)

Anaerobic soil 42685252

(triazine) 8.3 (90) 8.3 (90)

43387714 (triazine) 8.6 (60) 4.7 (90)

Anaerobic Aquatic

Metabolism 43387716

(triazine) 37.0 (90) 18.6 (365)

Aerobic Aquatic

Metabolism 43387718

(triazine) 9.0 (30) 9.0 (30)

CGA-159902 Hydrolysis 42685247

(phenyl) 64.4 (24 days, pH 5, 25 o C)

0.9 (30 days, pH 7, 25 o C)

1.3 (24 days, pH 9, 25 o C) 58.5 (30 days, pH 5, 25 o C)

0.9 (30 days, pH 7, 25 o C)

0.8 (30 days, pH 9, 25 o C)

Photodegradation

in water 42685249

(phenyl) 1.5 (30, pH 9, 25 o C, dark)

1.4 (30, pH 9, 25 o C, irradiated) 1.5 (30, pH 9, 25 o C, dark)

1.4 (30, pH 9, 25 o C, irradiated)

Photodegradation

in soil 43159327

(phenyl) 4.9 (30, pH 7.2, 23.5 o C, dark)

6.8 (30, pH 7.2, 23.2 o C, irradiated) 4.9 (30, pH 7.2, 23.5 o C, dark)

6.8 (30, pH 7.2, 23.2 o C, irradiated)

Aerobic soil 42685251 (phenyl) 49 (366) 49 (366)

43387713 (phenyl) 47.8 (274) 47.6 (366)

Anaerobic soil 42685253 (phenyl) 22.4 (92) 22.4 (92)

43387715

(phenyl) 7.5 (90) 7.5 (90)

Anaerobic Aquatic

Metabolism 43387717

(phenyl) 60.1(91) 58.6 (364)

Aerobic Aquatic

Metabolism 43387719 1.3 (30) 1.3 (30)

### Page 129 of 318 Transformation

Product Study Type MRID Maximum %AR (day) Final %AR (study length)

CGA-188838 Anaerobic Aquatic

Metabolism 43387716

(triazine) 9.6 (365) 9.6 (365)

G-28533 Hydrolysis 42685246

(triazine) 16.6 (30, pH 5, 25 o C) 16.6 (30, pH 5, 25 o C)

Anaerobic Soil 43387714 (triazine) 1.5 (90) 1.5 (90)

Anaerobic Aquatic

Metabolism 43387716

(triazine) 24.3 (274) 19.9 (365)

CGA-300406 Hydrolysis 42685246

(triazine) 8.6 (30, pH 5, 25 o C)

0.5 (30, pH 7, 25 o C)

2.6 (30, pH 9, 25 o C) 46.1 (30, pH 5, 25 o C)

0.5 (30, pH 7, 25 o C)

2.6 (30, pH 9, 25 o C)

42685247

(phenyl) 15.4 (7 days, pH 5, 25 o C)

0.4 (24 days, pH 7, 25 o C)

2.3 (30 days, pH 9, 25 o C) 6.8 (30 days, pH 5, 25 o C)

0.2 (30 days, pH 7, 25 o C)

2.3 (30 days, pH 9, 25 o C)

Photodegradation

in water 42685248

(triazine) 3.3 (30, pH 9, 25 o C, dark)

2.8 (21, pH 9, 25 o C, irradiated) 3.3 (30, pH 9, 25 o C, dark)

2.6 (30, pH 9, 25 o C, irradiated)

42685249

(phenyl) 3.6 (30, pH 9, 25 o C, dark)

3.3 (30, pH 9, 25 o C, irradiated) 3.6 (30, pH 9, 25 o C, dark)

3.3 (30, pH 9, 25 o C, irradiated)

Photodegradation

in soil 43159328

(triazine) 2.6 (30, pH 7.2, 23.5 o C, dark)

4.1 (30, pH 7.2, 23.2 o C, irradiated) 2.6 (30, pH 7.2, 23.5 o C, dark)

4.1 (30, pH 7.2, 23.2 o C, irradiated)

43159327

(phenyl) 4.1 (30, pH 7.2, 23.5 o C, dark)

4.9 (30, pH 7.2, 23.2 o C, irradiated) 4.1 (30, pH 7.2, 23.5 o C, dark)

4.9 (30, pH 7.2, 23.2 o C, irradiated)

Anaerobic Soil 43387714 (triazine) 4.6 (90) 4.6 (90)

42685252

(triazine) 9.1 (90) 9.1 (90)

42685253 (phenyl) 8.3 (92) 8.3 (92)

43387715 4.1 (90) 4.1 (90)

### Page 130 of 318 Transformation

Product Study Type MRID Maximum %AR (day) Final %AR (study length)

(phenyl)

Aerobic soil 43387713 (phenyl) 6.2 (184) 5.0 (366)

43387712

(triazine) 6.0 (180) 3.8 (364)

42685251 (phenyl) 7.1 (184) 2.7 (366)

42685250 (triazine) 10.4 (90) 3.2 (366)

Anaerobic Aquatic

Metabolism 43387717

(phenyl) 14.6 (14) undetected (364)

43387716

(triazine) 15.5 (14) undetected (364)

Aerobic Aquatic

Metabolism 43387718

(triazine) 2.6 (20) 1.9 (30)

43387719

(phenyl) 3.0 (30) 3.0 (30)

CGA-325025 Aerobic soil 43387712 (triazine) 5.8 (60) undetected (366)

42685250 (triazine) 21.6 (366) 21.6 (366)

43387713 (phenyl) 12.5 (122) 0.6 (366)

Anaerobic soil 42685252

(triazine) 25.3 (90) 25.3 (90)

43387714 (triazine) 10 (90) 10(90)

43387715

(phenyl) 18.3 (90) 18.3 (90)

Aerobic Aquatic

Metabolism 43387718

(triazine) 9.6 (20) 7.8 (30)

### Page 131 of 318 Transformation

Product Study Type MRID Maximum %AR (day) Final %AR (study length)

Aerobic Aquatic

Metabolism 43387719

(phenyl) 8.5 (30) 8.5 (30)

CGA-325030 Hydrolysis 42685246

(triazine) 22.2 (30, pH 5, 25 o C) 22.2 (30, pH 5, 25 o C)

42685247

(phenyl) 41.1 (30days, pH 5, 25 o C) 41.1 (30 days, pH 5, 25 o C)

Anaerobic Aquatic

Metabolism 43387717

(phenyl) 13.4(60) undetected (364)

43387716

(triazine) 15.6 (30) undetected (364)

CGA-325028 Aerobic soil 43387712 (triazine) 2.6 (366) 2.6 (366)

43387713 (phenyl) 1.9 (366) 1.9 (366)

Anaerobic Aquatic

Metabolism 43387717

(phenyl) 27.8 (364) 27.8 (364)

Anaerobic Aquatic

Metabolism 43387716

(triazine) 26.9 (273) 24.7 (365)

CGA-325026 Anaerobic Aquatic

Metabolism 43387717

(phenyl) 4.9 (273) 4.5 (364)

CGA-325027 Aerobic soil 43387713 (phenyl) 2.5 (366) 2.5 (366)

Anaerobic soil 43387715

(phenyl) 1.6 (90) 1.6 (90)

Anaerobic Aquatic

Metabolism 43387717

(phenyl) 4.5 (273) 4.1 (364)

NANC-CGA159902 Anaerobic Aquatic

Metabolism 43387717

(phenyl) 2.9 (91) 2.0 (364)

Anaerobic Aquatic

Metabolism 43387716

(triazine) 3.0 (59) 2.9 (365)

### Page 132 of 318 Abbreviations: %AR=percent ap plied radioactivity present as the identified compound



### Rimsulfuron

### Page 133 of 318 Sulfometuron-methyl

Chemical Structures

Trivial or common names Company ID or similar alternate names

Full chemical names

Sulfometuron methyl DPX-T5648; DPX-5648; IN-T5648; IN

T5648-18 Methyl 2-(4,6-dimethylpyrimidin-2-

ylcarbamoylsulfamoyl)benzoate Saccharin

IN-581 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide

Sulfometuron pyrimidine amine IN-X0993; IN-X993; PA 4,6-Dimethyl-2-pyrimidinamine 4,6-dimethyl-2-pyrimidinamine Sulfometuron sulfonamide IN-D5803; SA; methyl phenylsulfonamide Methyl 2-(aminosulfonyl)benzoate. 2-(Aminosulfonyl)-benzoic acid, methyl ester

### Page 134 of 318 Pyrimidine-ol

IN-11859 4,6-Dimethyl-2-pyrimidinol Sulfometuron free acid FA-SM; IN-T6385 2-[[[[(4,6-Dimethyl-2- pyrimidinyl)amino]carbonyl]amino]sulfonyl]-

benzoic acid

Free acid Sulfonamide FA-Sulfonamide; Free acid; IN-D5119 2-(Aminosulfonyl)benzoic acid 

## O O H

S

O O

N

H H

### Page 135 of 318 Sulfosulfuron

Common Name (CAS #, if available) Chemical Name Degradation Process Forming

Metabolite: Percent Formed: MRID

Desmethyl N -[[(4-Hydroxy-6-dimethoxy-2- pyrimidinyl)amino]carbonyl]-2- (ethylsulfonyl)imidazo[1,2- a]pyridine-3-sulfonamide Aerobic soil metabolism: extractable-2.58% and 1.8% of the applied 14 C-activity at day 360; bound-1.15% and 0.97% of the applied 14 C-activity at day 360 (This minor route of transformation involves the demethylation of sulfosulfuron to yield desmethyl, which is further degraded to guanidine): 442957-23

Aerobic soil metabolism: extractable-5.2%, 2.6% and 1.9% of the applied 14 C-activity at day 100 in 3 soils:

442957-31

Aerobic aquatic metabolism: 14 and 13% at day 30, <1% in sterile system only: 442957-26

Anaerobic aquatic metabolism: 11.6% and  6.3% of the applied dose at day 365; 2.0% in sterile solution at day

365: 442957-25

Soil column leaching: 2.7% of applied dose in

leachates: 442957-27

Sulfamic acid [[(4,6-dimethyoxy-2- pyrimidinyl)amino]carbonyl]-

sulfamic acid Aqueous photolysis: 14% at 48 hour, 19% at 96 hours, 21% at 6 days: 442957-21

Aminopyrimidine 4,6-dimethoxy-2-pyri midinamine Hydrolysis: 92% (pH 4), 31% (pH 5), 12% (pH 7), and 15% (pH 9) at 30 days: 442957-20

Aqueous photolysis: 10% at 48 hours, 24% at 96 hours, 28% at 6 days: 442957-21

Aerobic soil metabolism: extractable – 39.92% and 29.33 % of the applied 14 C-activity; bound 27.10 and 32.96% at day 360: 442957-23

Aerobic soil metabolis m: 1.7%: 442957-26

Soil column leaching: limited mobility - <2% of applied dose in leachates: 442957-27

Anaerobic aquatic metabolism: 13% at day 365 (identified at hydrolysis product): 442957-25

Sulfonamide

(63-74-1) 2-(ethylsulfonyl)-imidazo[1,2- a]pyridine-3-sulfonamide Hydrolysis: 93% (pH 4), 34% (pH 5), 13% (pH 7), and 15% (pH 9) at 30 days: 442957-20

Aerobic soil metabolism: Extractable- 54.69% and 46.66 % (maximum 14 C-activity) ; bound 15.29 and 14.46% of amount applied at 360 days: 442957-23

### Page 136 of 318 Aerobic soil metabolism: 6.1% : 442957-26

Aerobic soil metabolism: 3,7%, 4.4%, and 12.8 % (maximum 14 C-activity) at day 100: 442957-31

Aerobic aquatic system: Mi nor transformation product (6.1%). (Identified as hydrolysis product): 442957-26

Anaerobic aquatic system: Major transformation product 64.9% of 14 C-activity at day 365 (Identified as hydrolysis product): 442957-25

Soil photolysis: irradiated -1 3% at day 14, and 22.6% at Day 30, dark control 24.4% at day 30; 442957-22

Soil column leaching: 2% of applied dose in leachates:

442957-27

Sulfonic acid

(27176-87-0) 2-(ethylsulfonyl)-imidazo[1,2- a]pyridine-3-sulfonic acid Aqueous photolysis: 13% at 72 hours, 15% at 96 hours, 13% at 6 days: 442957-21

Aerobic soil metabolism: Mino r transformation product (<0.5%): 442957-31

Aquatic sediment: Not mentioned in aerobic aquatic systems study: 442957-26

Sulfone 2-(ethylsulfonyl)-imidazo[1,2- a]pyridine Aqueous photolysis: 14% at 24 hours; 28% at 96 hours and 21% at 6 days: 442957-21

Urea (4,6-dimethoxy-2-pyrimidinyl)-

urea Anaerobic aquatic metabolis m: 29.2% (postulated to form due to elevated ammonia in system): 442957-25

N-hydroxy urea N-(4,6-dimethoxy-2- pyrimidinyl)-N’-hydroxy-urea Aqueous photolysis: 13% at 24 hours, 15% at 48 hours,

7% at 96 hours: 442957-21

Oxamic acid 2-imino-alpha-oxo-1 (2H)- pyridineacetic acid Aqueous photolysis: 12% at 96 hours; 16% at 6 days:

442957-21

### Page 137 of 318

### Page 138 of 318 Thifensulfuron-methyl

Table 3. Thifensulfuron methyl Major and Minor Degradates Degradate IUPAC Name Structure Formation

Route Degradate Classification (% AR)* Reference

IN-L9225 3-[({[(4-Methoxy-6-methyl-1,3,5-triazine2- yl)amino]carbonyl}amino)sulfonyl]thiophene2-carboxylic acid Aerobic aquatic

metabolism Major (up to 55% AR) MRID 48043101

IN-JZ789 3-[({[(4-Hydroxy-6-methyl-1,3,5-triazine2- yl)amino]carbonyl}amino)sulfonyl]thiophene2-carboxylic acid Aerobic aquatic

metabolism Major (up to 21% AR) MRID 48043101

IN-W8268 Thieno[2,3- d]isothiazol-3(2H)-one 1,1-dioxide Aerobic aquatic

metabolism Minor (<10% AR) MRID 48043101

IN-L9226 Methyl 3-[({[(4-hydroxy-6-methyl1,3,5-triazin-2- yl)amino]carbonyl}amino)sulfonyl]thiophene2-carboxylate Aerobic soil

metabolism Major (15% AR) M RID 00145154

IN-L9223 3- (Aminosulfonyl)thioph ene-2-carboxylic acid Aerobic aquatic

metabolism Hydrolysis

Soil photolysis Major (up to 39% AR)

Major (up to 64% AR) Minor (< 10% AR) MRID 48043101

MRID 00145151

MRID 00161286

IN-V7160 N-(4-Methoxy-6- methyl-1,3,5-triazin-2- yl)urea Aerobic aquatic

metabolism Major (up to 25% AR) MRID 48043101

IN-A4098 4-Methoxy-6-methyl1,3,5-triazin-2-amine Aerobic aquatic

metabolism Hydrolysis

Soil photolysis Major (up to 19% AR)

Minor (<10% AR) Minor (< 10% AR) MRID 48043101

MRID 00145151

MRID 00161286

IN-B5528 4-Amino-6-methyl1,3,5-triazin-2-ol Aerobic aquatic

metabolism Minor (< 10% AR) MRID 48043101 S O O H

S N H N H O

O O

N N N O CH 3

CH 3

S O O H

S N H N H O

O O

N N N OH

CH 3

S S N O

O

O

S O O C H 3

S N H N H O

O O

N N N OH

CH 3

S O O H

S NH 2 O

O

N H 2 N H O

N N N O CH 3

CH 3

N H 2 N N N O CH 3

CH 3

N H 2 N N N OH

CH 3

### Page 139 of 318 * % RA - Percent of applied radioactivity



### Triasulfuron

### Page 140 of 318

### Page 141 of 318 SYN546702

N

H H O H

N

H N N H

O N H

S

O O O C H 2 C H 2 Cl

### Page 142 of 318 Tribenuron-methyl

Degradate IUPAC Name Structure Formation

Route Degradate

Classification (% AR)* Reference

IN-00581

Saccharin 1,2-

Benzisothiazol3(2H)-one 1,1-

dioxide Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism

Hydrolysis (15.0% in

water 8.2% in soil)

(32.0% in

water
6.4% in sediment)

(82% at pH 7) MRID

47643011

MRID

47643005

MRID

47643010

IN-GK521O-demethyltribenuron Methyl 2-[({[(4- hydroxy-6- methyl-1,3,5- triazin-2-yl) (methyl)amino]c arbonyl}amino)s ulfonyl]benzoate Anaerobic aquatic

metabolism (10.3% in

water 6.0% in soil) MRID

47643011

IN-L5296

Triazine

amine 4-Methoxy-N,6- dimethyl-1,3,5-

triazin-2-amine Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism

Hydrolysis

Photolysis

Aerobic soil

metabolism (7.0% in water 16.6% in soil)

(42.4% in

water
85.5% in

sediment

max detects at different time)

(97% at pH 5 and 7)

(6.5%)

(91.1%) MRID

47643011

MRID

47643005

MRID

47643010

MRID

40245520

MRID

40245522

IN-D5119

Acid

sulfobamide 2- (Aminosulfonyl)

benzoic acid Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism

Hydrolysis (6.1% in water 0.2% in soil)

(18.5% in

water
7.5% in sediment)

(2% at pH 9) MRID

47643011

MRID

47643005

MRID

47643010 S N H O

O

O

O S O

O N

H O

N N

N

N C H 3

O H CH 3

O CH 3

N N

N

N C H 3

O C H 3 H CH 3

O S O

O N

OH H H

### Page 143 of 318 IN-R9803

Tribenuron

free acid 2-[({[(4- Methoxy-6- methyl-1,3,5- triazin-2-yl) (methyl)amino]c arbonyl}amino)s ulfonyl]benzoic

acid Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism (5.7% in water 1.5% in soil)

(3.4% in sediment) MRID

47643011

MRID

47643005

IN-GN815O-demethyltribenuron

free acid 2-[({[(4- Hydroxy-6- methyl-1,3,5- triazin-2-yl) (methyl)amino]c arbonyl}amino)s ulfonyl]benzoic

acid Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism (5.9% in water 0.9% in soil)

(5.70% in

water
5.5% in sediment) MRID

47643011

MRID

47643005

IN-R9805O-demethyltriazine amine 4-Methyl-6- (methylamino)- 1,3,5-triazin-2-ol Anaerobic aquatic

metabolism

Aerobic aquatic

metabolism

Hydrolysis

Photolysis

Aerobic soil

metabolism (3.0% in water 2.1% in soil)

(9.0% in water

5.7% in sediment)

(6% at pH 5)

(2.2%)

(26.1%) MRID

47643011

MRID

47643005

MRID

47643010

MRID

40245520

MRID

40245522

IN-A4098N-demethyltriazine amine 4-Methoxy-6- methyl-1,3,5-

triazin-2-amine Aerobic aquatic

metabolism (2.4% in water

3.6% in sediment) MRID

47643005

IN-D5803

Sulfonamide Methyl 2- (aminosulfonyl)b

enzoate Aerobic aquatic

metabolism

Hydrolysis (6.6% in water)

(96% at pH 5) (52% at pH 7) MRID

47643005

MRID

47643010
* % AR - Percent of applied radioactivity O
OH S O

O N

H O

N N

N

N C H 3

O C H 3 CH 3

O S O

O N

H O

N N

N

N C H 3

O H CH 3

OH

N N

N

N C H 3

O H H CH 3

N N

N

N C H 3

H

O C H 3 H

O S O

O N

O CH 3 H H

### Page 144 of 318 Trifloxysulfuron-Na

STRUCTURES, CHEMICAL NAMES, and ABBREVIATIONS

### Page 145 of 318

### Page 146 of 318

### Page 147 of 318

### Page 148 of 318 Major Trifloxysulfuron-Sodium Environmental Transformation Products

Trifloxysulfuron

-sodium

Transformation

Products [ 14 C] Label Hydrolysis Aqueous Photolysis 2 Soil Photolysis 2 Aerobic

Soil

Metabolism Anaerobic Aquatic

Metabolism Aerobic Aquatic

Metabolism

%max/day/pH 1 Maximum % of applied radioactivity (day maximum occurred)

CGA 382997 Pyrimidine - - - - - -

Pyridine 64.0 (30 d; 4
52.5 (30 d;5)
4.8 (30 d; 7)
4.0 (30 d; 9) I: 5.3 (30 d)
D: 5.1 (30 d) I: 10.1 (30 d)
D: 17.2 (30 d) 54.1(273 d) 4.6 (270 d) 3 4.3 (100 d) 3

CGA 53052 Pyrimidine 61.1 (30 d; 4)
49.8 (30 d;5)
4.9 (30 d; 7)
3.3 (30 d; 9) I: 7.54 (30 d)
D: 9.2 (30 d) I: 3.3 (21 d)
D: 1.3 (14 d) 14.1(179 d) 3.8 (21 d) 4 3.2 (100 d) 4

Pyridine - - - - -

CGA 368733 Pyrimidine 2.7 (30 d; 4)
2.7 (30 d; 5)
8.1 (30 d; 7)
35.1 (30 d; 9) I: 6.4 (30 d)
D: 3.4 (30 d) - 26.7 (365 d) 7.1 (181 d) 4 37.0 (100 d) 4

Pyridine 1.9 (30 d; 4)
5.1 (30 d; 5)
9.3 (30 d; 7)
29.8 (30 d; 9) I: 7.8 (30 d)
D: 5.1 (26 d) I: 11.5 (30 d)
D: 3.2 (30 d) 16.4 (365 d) 6.4 (270 d) 4 14.1 (100 d) 4

CGA 368732 Pyrimidine 35.9 (30 d; 4)
42.3 (30 d; 5)
53.0 (30 d; 7)
23.0 (30 d; 9 I: 45.9 (30 d)
D: 51.1 (30 d) I: 25.5 (21 d)
D: 29.0 (30 d) 21.8 (90 d) 20.1 (21 d) 3 30.9 (59 d) 3

14 (59 d) 4

Pyridine 34.8 (30 d; 4)
39.3 (30 d; 5)
51.0 (30 d; 7)
26.5 (30 d; 9) I: 46.1 (30 d)
D: 49.0 (30 d) I: 6.2 (30 d)
D: 1.1 (30 d) 12.5 (91 d) 16.7 (22 d) 3 19.2 (21 d) 3

CGA 294409 Pyrimidine - I: 2.0 (3 d)
D: 5.8 (7 d) I: 2.4 (30 d) - - -

Pyridine - - - - -

NOA-436664 Pyrimidine - - I: 1.0 (30 d) - 45.7 (181 d) 4 7.7 (100 d) 4

Pyridine - - - - 37.2 (270 d) 4 21.5 (59 d) 4

1 Maximum percent of applied radioactivity, days after treatment maximum occurred, pH.

2 I = irradiated; D = Dark; Maximum percent of applied radioactivity and days after treatment.

3 Water fraction

4 Sediment fraction.

### Page 149 of 318 Triflusulfuron-methyl

Chemical Structure (from chemical’s data sheet, see above)



### Summary of degradate formation for triflusulfuron-methyl.

Common Name

Chemical Name Study: max observed; time of observation; study duration Structure N-desmethyl-DPX-66037 (MW = 478.41 g/mol)

Methyl-2-[[[[4- (methylamino)-6-(2,2,2- trifluoroethoxy)-1,3,5-

triazin-2- yl]amino]sulphonyl]-3- methylbenzoate Aqueous photolysis: 14.7% AR; 15 days; 15 days, pH 7 Soil photodegradation: 12.2% AR; 2 days; 15 days Aerobic aquatic metabolism: 3.0% AR; 100 days; 100 days

Methyl saccharin (MW = 197.21 g/mol)

7-Methyl-1,2- benzisothiazol-3(2H)-one 1,1-dioxide Hydrolysis: 99.4% AR; 30 days; 30 days, pH 5 Aqueous photolysis: 71.2% AR; 15 days; 15 days, pH 5 Soil photodegradation: 62.4% AR in dark

control & 11.7% AR irrad samples; 15 days; 15 days Aerobic soil metabolism: 83.7% AR; 29 days; 368 days Anaerobic soil metabolism: 74.6% AR; 5 + 62 days; 62 days Aerobic aquatic metabolism: 87.8% AR; 29 days; 100 days

Triazine amine (MW = 237.19 g/mol)

N,N-Dimethyl-6-(2,2,2- trifluoroethoxy)-1,3,5- triazine-2,4-diamine Hydrolysis: 98.4% AR; 30 days; 30 days, pH 5 Aqueous photolysis: 46.8% AR; 7 days; 15 days, pH 5 Soil photodegradation: 47.5% AR in dark

control & 11.8% AR irrad samples; 15 days; 15 days Aerobic soil metabolism: 55.2% AR; 21 days; 368 days Anaerobic soil metabolism: 56.9% AR; 5 + 62 days; 62 days Aerobic aquatic metabolism: 68.4% AR; 29 days; 100 days CH 3

O

C H 3 O S

O O

NH

O NH N

N

N NH CH 3

O

F

F
F

CH 3

N
H S O

O

O

N H 2 N

N

N N C H 3

O

F

F
F

CH 3

### Page 150 of 318 N-desmethyl triazine

amine (MW = 223.16 g/mol)

N,N-Methyl-6-(2,2,2- trifluoroethoxy)-1,3,5- triazine-2,4-diamine Aqueous photolysis: 6.9% AR; 15 days; 15 days, pH 5 Soil photodegradation: N.D. dark control & 6.9% AR irrad samples at 15 days; 15 days 

### Aerobic soil metabolism: 35.9% AR; 110 days; 368 days Anaerobic soil metabolism: 3.2% AR; 5 + 9 days; 62 days Aerobic aquatic metabolism: 15.6% AR; 61 days; 100 days

Bis-N,N-desmethyl

triazine amine (MW = 209.13 g/mol)

6-(2,2,2- Trifluoroethoxy)-1,3,5- triazine-2,4-diamine Aqueous photolysis: 0.2% AR; 15 days; 15 days, pH 5 Soil photodegradation: N.D. dark control & 4.2% AR irrad samples at 15 days; 15 days 

### Aerobic soil metabolism: 12.5% AR; 110 days; 368 days Aerobic aquatic metabolism: 1.7% AR; 61 days; 100 days N-formyl methyl triazine

amine (observed only in aqueous photolysis study)

N-[4-Amino-6-(2,2,2- trifluoroethoxy)-1,3,5-triazin-2-yl]-Nmethylformamide Aqueous photolysis: 20.1% AR; 15 days; 15 days, pH 5

Triazine urea (minor degradate)

N-[4-(Dimethylamino)-6- (2,2,2-trifluoroethoxy)- 1,3,5-triazin-2-yl]-urea Aqueous photolysis: 3.8% AR; 15 days; 15 days, pH 5 Soil photodegradation: 7.1% AR; 15 days; 15 days

N-Desmethyl triazine

urea (observed only in soil photodegradation study)

N-[4-(Methylamino)-6- (2,2,2-trifluoroethoxy)- 1,3,5-triazin-2-yl]-urea Soil photodegradation: 13.5% AR; 15 days; 15 days

FA-DPX-66037 (MW = 478.41 g/mol)

2-[[[[[4-(dimethylamino)- 6-(2,2,2-trifluoroethoxy)- 1,3,5-triazin-2- yl]amino]carbonyl]amino ]sulfonyl]-3- methylbenzoic acid Aerobic aquatic metabolism: 45.4% AR; 61-100 days; 100 days N H 2 N

N

N NH C H 3

O
F

F
F

N H 2 N

N

N NH 2

O
F

F
F

N H 2 N

N

N N

O
F

F
F C H 3

O

N H 2

O NH N

N

N N CH 3 C H 3

O

F

F
F

N H 2

O NH N

N

N NH C H 3

O

F

F
F

### Page 151 of 318 Appendix D. Collected IC 25 

### Values for Sulfonyl Urea Herbicides

The table is arranged alphabetically by chemical. Shaded rows are vegetative vigor.

Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

Bensulfuron

Ͳ methyl corn none SE > 0.533

Bensulfuron

Ͳ methyl cucumber none SE > 0.533

Bensulfuron

Ͳ methyl oat none SE > 0.533

Bensulfuron

Ͳ methyl oilseed rape height SE = 0.000154

Bensulfuron

Ͳ methyl onion height SE = 0.184

Bensulfuron

Ͳ methyl pea none SE > 0.533

Bensulfuron

Ͳ methyl ryegrass none SE > 0.533

Bensulfuron

Ͳ methyl soybean biomass SE = 0.096

Bensulfuron

Ͳ methyl sugar beet biomass SE = 0.0315

Bensulfuron

Ͳ methyl tomato none SE > 0.533

Bensulfuron

Ͳ methyl corn none VV > 0.0531

Bensulfuron

Ͳ methyl cucumber height VV = 0.00125

Bensulfuron

Ͳ methyl oat none VV > 0.0531

Bensulfuron

Ͳ methyl oilseed rape biomass VV = 0.000222

Bensulfuron

Ͳ methyl onion none VV > 0.0531

Bensulfuron

Ͳ methyl pea none VV > 0.0531

Bensulfuron

Ͳ methyl ryegrass none VV > 0.0531

Bensulfuron

Ͳ methyl soybean biomass VV = 0.000145

Bensulfuron

Ͳ methyl sugar beet height VV = 0.0215

Bensulfuron

Ͳ methyl tomato height VV = 0.000218

chlorimuron

Ͳ ethyl corn biomass SE = 0.0026

chlorimuron

Ͳ ethyl cucumber height SE = 0.00016

chlorimuron

Ͳ ethyl oilseed rape height SE < 0.00004

chlorimuron

Ͳ ethyl onion height SE = 0.000011

chlorimuron

Ͳ ethyl pea biomass SE = 0.0034

chlorimuron

Ͳ ethyl sorghum biomass SE = 0.0011

chlorimuron

Ͳ ethyl soybean biomass SE > 0.081

chlorimuron

Ͳ ethyl sugar beet height SE = 0.0002

chlorimuron

Ͳ ethyl tomato biomass SE = 0.00018

chlorimuron

Ͳ ethyl wheat biomass SE = 0.0022

chlorimuron

Ͳ ethyl corn biomass VV = 0.00052

### Page 152 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

chlorimuron

Ͳ ethyl cucumber height VV = 0.00065

chlorimuron

Ͳ ethyl oilseed rape height VV = 0.000033

chlorimuron

Ͳ ethyl onion biomass VV = 0.000043

chlorimuron

Ͳ ethyl pea biomass VV = 0.000087

chlorimuron

Ͳ ethyl sorghum biomass VV = 0.00058

chlorimuron

Ͳ ethyl soybean biomass VV = 0.004

chlorimuron

Ͳ ethyl sugar beet biomass VV = 0.000092

chlorimuron

Ͳ ethyl tomato biomass VV = 0.00024

chlorimuron

Ͳ ethyl wheat biomass VV = 0.0011

chlorsulfuron corn biomass SE = 0.0019

chlorsulfuron cucumber biomass SE = 0.0089

chlorsulfuron oat biomass SE = 0.0065

chlorsulfuron oilseed rape biomass SE = 0.00043

chlorsulfuron onion biomass SE = 0.0003

chlorsulfuron pea biomass SE = 0.00022

chlorsulfuron sorghum biomass SE = 0.002

chlorsulfuron soybean height SE = 0.012

chlorsulfuron sugar beet biomass SE = 0.00033

chlorsulfuron tomato biomass SE = 0.00032

chlorsulfuron corn biomass VV = 0.000366

chlorsulfuron cucumber biomass VV = 0.004

chlorsulfuron oat biomass VV = 0.0107

chlorsulfuron oilseed rape height VV = 0.0000098

chlorsulfuron onion biomass VV = 0.000022

chlorsulfuron pea biomass VV = 0.000013

chlorsulfuron sorghum biomass VV = 0.00018

chlorsulfuron soybean biomass VV = 0.000054

chlorsulfuron sugar beet biomass VV = 0.0000098

chlorsulfuron tomato biomass VV = 0.00014

flazasulfuron cabbage biomass SE = 0.00107

flazasulfuron carrot biomass SE = 0.00109

flazasulfuron corn biomass SE = 0.00262

flazasulfuron cucumber biomass SE = 0.012

flazasulfuron lettuce none SE > 0.04

### Page 153 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

flazasulfuron oat none SE > 0.04

flazasulfuron onion biomass SE = 0.0027

flazasulfuron radish biomass SE = 0.00261

flazasulfuron ryegrass biomass SE = 0.00261

flazasulfuron soybean biomass SE = 0.15

flazasulfuron cabbage biomass VV = 0.00037

flazasulfuron carrot biomass VV = 0.00015

flazasulfuron corn biomass VV = 0.00055

flazasulfuron cucumber biomass VV > 0.0014

flazasulfuron lettuce biomass VV = 0.00097

flazasulfuron oat biomass VV = 0.0009

flazasulfuron onion biomass VV = 0.00055

flazasulfuron radish height VV = 0.00004

flazasulfuron ryegrass biomass VV = 0.0004

flazasulfuron soybean biomass VV = 0.00029

foramsulfuron carrot biomass SE = 0.024976

foramsulfuron corn biomass SE > 0.0535

foramsulfuron cucumber biomass SE > 0.0535

foramsulfuron lettuce biomass SE = 0.0088308

foramsulfuron oat biomass SE > 0.0535

foramsulfuron onion biomass SE = 0.028544

foramsulfuron radish biomass SE = 0.025868

foramsulfuron ryegrass biomass SE = 0.009812

foramsulfuron soybean biomass SE > 0.0535

foramsulfuron tomato biomass SE = 0.02676

foramsulfuron carrot biomass VV = 0.000562086

foramsulfuron corn biomass VV > 0.0535

foramsulfuron cucumber height VV = 0.00019624

foramsulfuron lettuce biomass VV = 0.006959154

foramsulfuron oat biomass VV = 0.001249079

foramsulfuron onion biomass VV > 0.0535

foramsulfuron radish biomass VV = 5.17E

Ͳ 05

foramsulfuron ryegrass biomass VV = 0.001249079

foramsulfuron soybean height VV = 0.0016056

### Page 154 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

foramsulfuron tomato biomass VV = 0.001249079

halosulfuron

Ͳ methyl cabbage height SE = 0.0008

halosulfuron

Ͳ methyl corn biomass SE = 0.0027

halosulfuron

Ͳ methyl cucumber biomass SE = 0.0071

halosulfuron

Ͳ methyl lettuce height SE = 9.90E

Ͳ 05

halosulfuron

Ͳ methyl oat biomass SE = 0.2

halosulfuron

Ͳ methyl onion biomass SE = 0.0003

halosulfuron

Ͳ methyl radish biomass SE = 0.00061

halosulfuron

Ͳ methyl ryegrass biomass SE = 0.0011

halosulfuron

Ͳ methyl soybean height SE = 0.0041

halosulfuron

Ͳ methyl tomato height SE = 0.0083

halosulfuron

Ͳ methyl cabbage biomass VV = 0.00018

halosulfuron

Ͳ methyl corn biomass VV = 0.0082

halosulfuron

Ͳ methyl cucumber biomass VV = 0.071

halosulfuron

Ͳ methyl lettuce biomass VV = 0.00072

halosulfuron

Ͳ methyl oat biomass VV = 0.053

halosulfuron

Ͳ methyl onion biomass VV = 0.00075

halosulfuron

Ͳ methyl radish biomass VV = 0.000057

halosulfuron

Ͳ methyl ryegrass biomass VV = 0.004

halosulfuron

Ͳ methyl soybean biomass VV = 0.00076

halosulfuron

Ͳ methyl tomato biomass VV = 0.061

imazosulfuron buckwheat height SE > 2

imazosulfuron corn biomass SE > 2

imazosulfuron flax biomass SE = 0.067

imazosulfuron lettuce biomass SE = 0.041

imazosulfuron onion biomass SE = 0.034

imazosulfuron radish height SE = 1.6

imazosulfuron ryegrass biomass SE > 2

imazosulfuron soybean biomass SE > 2

imazosulfuron tomato biomass SE > 2

imazosulfuron wheat height SE > 2

imazosulfuron buckwheat height VV = 1.6

imazosulfuron corn biomass VV > 2

imazosulfuron flax height VV = 1.1

### Page 155 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

imazosulfuron lettuce biomass VV = 0.33

imazosulfuron onion biomass VV = 0.25

imazosulfuron radish surv VV = 0.08

imazosulfuron ryegrass height VV > 2

imazosulfuron soybean biomass VV = 0.69

imazosulfuron tomato biomass VV = 1.3

imazosulfuron wheat biomass VV > 2

iodosulfuron

Ͳ methyl

Ͳ Na cabbage height SE = 0.0004

iodosulfuron

Ͳ methyl

Ͳ Na corn height SE > 0.0027

iodosulfuron

Ͳ methyl

Ͳ Na cucumber height SE > 0.0027

iodosulfuron

Ͳ methyl

Ͳ Na lettuce height SE = 0.000045

iodosulfuron

Ͳ methyl

Ͳ Na oat biomass SE = 0.004

iodosulfuron

Ͳ methyl

Ͳ Na onion height SE = 0.00028

iodosulfuron

Ͳ methyl

Ͳ Na ryegrass biomass SE = 0.00031

iodosulfuron

Ͳ methyl

Ͳ Na soybean biomass SE > 0.0027

iodosulfuron

Ͳ methyl

Ͳ Na tomato height SE = 3.50E

Ͳ 06

iodosulfuron

Ͳ methyl

Ͳ Na turnip biomass SE = 0.0011

iodosulfuron

Ͳ methyl

Ͳ Na cabbage biomass VV = 0.0000089

iodosulfuron

Ͳ methyl

Ͳ Na corn biomass VV > 0.0027

iodosulfuron

Ͳ methyl

Ͳ Na cucumber biomass VV = 0.000071

iodosulfuron

Ͳ methyl

Ͳ Na lettuce height VV = 3.70E

Ͳ 10

iodosulfuron

Ͳ methyl

Ͳ Na oat height VV > 0.0027

iodosulfuron

Ͳ methyl

Ͳ Na onion biomass VV = 0.0000067

iodosulfuron

Ͳ methyl

Ͳ Na ryegrass height VV = 0.000028

iodosulfuron

Ͳ methyl

Ͳ Na soybean height VV = 0.000063

iodosulfuron

Ͳ methyl

Ͳ Na tomato biomass VV = 0.000025

iodosulfuron

Ͳ methyl

Ͳ Na turnip biomass VV = 0.000089

mesosulfuron

Ͳ methyl cabbage biomass SE = 0.00981

mesosulfuron

Ͳ methyl corn biomass SE > 0.01338

mesosulfuron

Ͳ methyl cucumber biomass SE = 0.0107

mesosulfuron

Ͳ methyl lettuce height SE = 0.00082

mesosulfuron

Ͳ methyl oat height SE = 0.00981

mesosulfuron

Ͳ methyl onion height SE = 0.00749

mesosulfuron

Ͳ methyl radish height SE = 0.00268

### Page 156 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

mesosulfuron

Ͳ methyl soybean biomass SE = 0.00642

mesosulfuron

Ͳ methyl tomato biomass SE = 0.00669

mesosulfuron

Ͳ methyl wheat biomass SE > 0.011596

mesosulfuron

Ͳ methyl cabbage biomass VV = 0.00017

mesosulfuron

Ͳ methyl corn biomass VV = 0.00041

mesosulfuron

Ͳ methyl cucumber biomass VV = 0.00041

mesosulfuron

Ͳ methyl lettuce biomass VV = 0.0002

mesosulfuron

Ͳ methyl oat biomass VV = 0.00037

mesosulfuron

Ͳ methyl onion biomass VV = 0.00053

mesosulfuron

Ͳ methyl radish biomass VV = 0.00019

mesosulfuron

Ͳ methyl soybean biomass VV = 0.00014

mesosulfuron

Ͳ methyl tomato biomass VV = 0.00016

mesosulfuron

Ͳ methyl wheat biomass VV = 0.00776

metsulfuron

Ͳ methyl corn biomass SE = 0.00518

metsulfuron

Ͳ methyl cucumber biomass SE = 0.000788

metsulfuron

Ͳ methyl oat biomass SE > 0.008

metsulfuron

Ͳ methyl oilseed rape biomass SE = 0.0013

metsulfuron

Ͳ methyl onion height SE = 0.00151

metsulfuron

Ͳ methyl pea biomass SE = 0.000436

metsulfuron

Ͳ methyl ryegrass biomass SE = 0.00335

metsulfuron

Ͳ methyl soybean height SE = 0.00778

metsulfuron

Ͳ methyl sugar beet biomass SE = 0.000322

metsulfuron

Ͳ methyl tomato biomass SE = 0.000578

metsulfuron

Ͳ methyl corn biomass VV = 0.00114

metsulfuron

Ͳ methyl cucumber biomass VV = 0.000139

metsulfuron

Ͳ methyl oat biomass VV = 0.00106

metsulfuron

Ͳ methyl oilseed rape height VV = 0.000387

metsulfuron

Ͳ methyl onion biomass VV = 0.000109

metsulfuron

Ͳ methyl pea biomass VV = 0.000826

metsulfuron

Ͳ methyl ryegrass biomass VV = 0.00214

metsulfuron

Ͳ methyl soybean height VV = 0.000158

metsulfuron

Ͳ methyl sugar beet biomass VV = 0.0000887

metsulfuron

Ͳ methyl tomato biomass VV = 0.0000985

nicosulfuron corn biomass SE > 0.053

### Page 157 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

nicosulfuron cucumber biomass SE = 0.0105

nicosulfuron oat height SE = 0.0329

nicosulfuron oilseed rape height SE = 0.0089

nicosulfuron onion height SE = 0.0535

nicosulfuron pea none SE > 0.052

nicosulfuron sorghum biomass SE = 0.000954

nicosulfuron soybean biomass SE = 0.0418

nicosulfuron sugar beet biomass SE = 0.0225

nicosulfuron tomato biomass SE = 0.0179

nicosulfuron cucumber biomass VV = 0.00262

nicosulfuron oat biomass VV = 0.0114

nicosulfuron oilseed rape biomass VV = 0.00208

nicosulfuron onion biomass VV = 0.0235

nicosulfuron pea height VV = 0.0439

nicosulfuron sorghum biomass VV = 0.00613

nicosulfuron soybean biomass VV > 0.055

nicosulfuron sugar beet biomass VV = 0.00764

nicosulfuron tomato biomass VV = 0.00384

nicosulfuron wheat biomass VV = 0.0105

orthosulfamuron carrot biomass SE = 0.097

orthosulfamuron corn biomass SE > 0.135

orthosulfamuron mung bean biomass SE > 0.135

orthosulfamuron oat biomass SE > 0.135

orthosulfamuron oilseed rape biomass SE > 0.135

orthosulfamuron onion height SE > 0.135

orthosulfamuron pea biomass SE = 0.093

orthosulfamuron radish biomass SE = 0.04

orthosulfamuron rice biomass SE = 0.078

orthosulfamuron soybean biomass SE > 0.135

orthosulfamuron carrot biomass VV = 0.00012

orthosulfamuron corn height VV = 0.0057

orthosulfamuron mung bean biomass VV < 0.00169

orthosulfamuron oat biomass VV > 0.115

orthosulfamuron oilseed rape biomass VV > 0.115

### Page 158 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

orthosulfamuron onion biomass VV = 0.0048

orthosulfamuron pea height VV < 0.00169

orthosulfamuron radish biomass VV = 0.00022

orthosulfamuron rice biomass VV = 0.032

orthosulfamuron soybean height VV < 0.0017
primisulfuron

Ͳ methyl cabbage biomass SE = 0.00031
primisulfuron

Ͳ methyl carrot biomass SE = 0.000397
primisulfuron

Ͳ methyl corn biomass SE = 0.002837
primisulfuron

Ͳ methyl cucumber height SE = 0.000132
primisulfuron

Ͳ methyl lettuce height SE = 0.000134
primisulfuron

Ͳ methyl oat height SE = 0.004389
primisulfuron

Ͳ methyl onion height SE = 0.000272
primisulfuron

Ͳ methyl ryegrass height SE = 0.000171
primisulfuron

Ͳ methyl soybean height SE = 0.039248
primisulfuron

Ͳ methyl tomato biomass SE = 0.000216
primisulfuron

Ͳ methyl cabbage biomass VV = 0.000513
primisulfuron

Ͳ methyl carrot biomass VV = 0.000204
primisulfuron

Ͳ methyl corn biomass VV = 0.029793
primisulfuron

Ͳ methyl cucumber height VV = 0.000127
primisulfuron

Ͳ methyl lettuce height VV = 0.000221
primisulfuron

Ͳ methyl oat biomass VV = 0.00071
primisulfuron

Ͳ methyl onion biomass VV = 0.000576
primisulfuron

Ͳ methyl ryegrass biomass VV = 0.001249
primisulfuron

Ͳ methyl soybean height VV = 0.006298
primisulfuron

Ͳ methyl tomato height VV = 0.000663
prosulfuron cabbage biomass SE = 0.0012
prosulfuron corn biomass SE > 0.0025
prosulfuron cucumber biomass SE = 0.00052
prosulfuron lettuce biomass SE = 0.000071
prosulfuron oat biomass SE > 0.04
prosulfuron onion height SE = 0.00026
prosulfuron radish biomass SE = 0.00037
prosulfuron ryegrass biomass SE > 0.00125
prosulfuron soybean height SE = 0.0016

### Page 159 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

prosulfuron tomato biomass SE = 0.0012
prosulfuron cabbage biomass VV = 0.0011
prosulfuron corn biomass VV > 0.04
prosulfuron cucumber biomass VV > 0.025
prosulfuron lettuce biomass VV = 0.0014
prosulfuron oat biomass VV > 0.04
prosulfuron onion biomass VV = 0.00041
prosulfuron radish biomass VV = 0.0011
prosulfuron ryegrass height VV = 0.0012
prosulfuron soybean biomass VV = 0.00046
prosulfuron tomato biomass VV = 0.0035

rimsulfuron corn biomass SE = 0.0117

rimsulfuron cucumber biomass SE = 0.00167

rimsulfuron oat biomass SE = 0.00998

rimsulfuron oilseed rape height SE = 0.000858

rimsulfuron onion height SE = 0.00115

rimsulfuron pea biomass SE = 0.00455

rimsulfuron sorghum biomass SE = 0.000164

rimsulfuron soybean height SE = 0.0217

rimsulfuron sugar beet biomass SE = 0.000521

rimsulfuron tomato biomass SE = 0.0232

rimsulfuron corn biomass VV = 0.064

rimsulfuron cucumber biomass VV = 0.0298

rimsulfuron oat biomass VV = 0.00142

rimsulfuron oilseed rape height VV = 0.000274

rimsulfuron onion biomass VV = 0.00214

rimsulfuron pea biomass VV = 0.00306

rimsulfuron sorghum biomass VV = 0.000821

rimsulfuron soybean biomass VV = 0.003

rimsulfuron sugar beet biomass VV = 0.00318

rimsulfuron tomato biomass VV > 0.061

sulfometuron

Ͳ methyl corn height SE = 0.00651

sulfometuron

Ͳ methyl cucumber biomass SE = 0.00818

sulfometuron

Ͳ methyl oilseed rape biomass SE = 0.00013

### Page 160 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

sulfometuron

Ͳ methyl onion biomass SE = 0.00023

sulfometuron

Ͳ methyl pea biomass SE = 0.00723

sulfometuron

Ͳ methyl sorghum height SE = 0.00019

sulfometuron

Ͳ methyl soybean height SE = 0.0423

sulfometuron

Ͳ methyl sugar beet height SE = 0.00011

sulfometuron

Ͳ methyl tomato biomass SE = 0.000078

sulfometuron

Ͳ methyl wheat height SE = 0.0003

sulfometuron

Ͳ methyl corn biomass VV = 0.000037

sulfometuron

Ͳ methyl cucumber height VV = 0.00024

sulfometuron

Ͳ methyl oilseed rape biomass VV = 0.000099375

sulfometuron

Ͳ methyl onion biomass VV = 0.00071

sulfometuron

Ͳ methyl pea biomass VV = 0.00023625

sulfometuron

Ͳ methyl sorghum biomass VV = 0.000055875

sulfometuron

Ͳ methyl soybean biomass VV = 0.000018

sulfometuron

Ͳ methyl sugar beet biomass VV = 0.000056

sulfometuron

Ͳ methyl tomato biomass VV = 0.00016125

sulfometuron

Ͳ methyl wheat biomass VV = 0.000120625

sulfosulfuron cabbage biomass SE = 0.0021

sulfosulfuron corn height SE = 0.0057

sulfosulfuron cucumber biomass SE > 0.001

sulfosulfuron lettuce height SE = 0.0028

sulfosulfuron oat biomass SE = 0.014

sulfosulfuron onion biomass SE = 0.0011

sulfosulfuron radish height SE = 0.0015

sulfosulfuron ryegrass biomass SE = 0.0038

sulfosulfuron soybean height SE = 0.0046

sulfosulfuron tomato biomass SE = 0.012

sulfosulfuron cabbage biomass VV = 0.0013

sulfosulfuron corn biomass VV = 0.0074

sulfosulfuron cucumber biomass VV = 0.0246

sulfosulfuron lettuce biomass VV = 0.0043

sulfosulfuron oat biomass VV = 0.0054

sulfosulfuron onion biomass VV = 0.0041

sulfosulfuron radish biomass VV = 0.00009

### Page 161 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

sulfosulfuron ryegrass biomass VV = 0.0041

sulfosulfuron soybean biomass VV = 0.00063

sulfosulfuron tomato height VV = 0.051

thifensulfuron

Ͳ methyl corn biomass SE > 0.00194375

thifensulfuron

Ͳ methyl cucumber biomass SE > 0.00194375

thifensulfuron

Ͳ methyl oat biomass SE > 0.00194375

thifensulfuron

Ͳ methyl oilseed rape biomass SE = 0.000204375

thifensulfuron

Ͳ methyl onion biomass SE = 3.46875E

Ͳ 05

thifensulfuron

Ͳ methyl pea biomass SE > 0.00194375

thifensulfuron

Ͳ methyl ryegrass biomass SE = 0.000431875

thifensulfuron

Ͳ methyl soybean biomass SE > 0.00194375

thifensulfuron

Ͳ methyl sugar beet biomass SE = 4.15625E

Ͳ 05

thifensulfuron

Ͳ methyl tomato biomass SE = 0.011

thifensulfuron

Ͳ methyl corn biomass VV = 0.00438125

thifensulfuron

Ͳ methyl cucumber biomass VV = 0.000375625

thifensulfuron

Ͳ methyl oilseed rape biomass VV = 3.65625E

Ͳ 05

thifensulfuron

Ͳ methyl onion biomass VV = 0.000048875

thifensulfuron

Ͳ methyl pea biomass VV = 0.001825

thifensulfuron

Ͳ methyl sorghum biomass VV = 0.00008625

thifensulfuron

Ͳ methyl soybean biomass VV = 0.0133125

thifensulfuron

Ͳ methyl sugar beet biomass VV = 3.01875E

Ͳ 05

thifensulfuron

Ͳ methyl tomato biomass VV = 0.00085625

thifensulfuron

Ͳ methyl wheat biomass VV = 0.03375

triasulfuron cabbage height SE = 0.00063

triasulfuron carrot height SE = 0.00062

triasulfuron corn biomass SE = 0.00152

triasulfuron cucumber height SE = 0.00184

triasulfuron lettuce height SE = 0.000085

triasulfuron oat height SE = 0.02364

triasulfuron onion height SE = 0.00017

triasulfuron ryegrass height SE = 0.00093

triasulfuron soybean biomass SE = 0.00054

triasulfuron tomato height SE = 0.00144

triasulfuron cabbage biomass VV = 0.000347

### Page 162 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

triasulfuron carrot biomass VV = 0.00025

triasulfuron corn height VV = 0.006128

triasulfuron cucumber biomass VV = 0.00027

triasulfuron lettuce height VV = 0.0000339

triasulfuron oat biomass VV > 0.07

triasulfuron onion height VV = 0.0004415

triasulfuron ryegrass biomass VV = 0.00022389

triasulfuron soybean biomass VV = 0.000429

triasulfuron tomato biomass VV = 0.000272
trifloxysulfuron

Ͳ Na carrot height SE = 0.00731
trifloxysulfuron

Ͳ Na corn height SE = 0.00740
trifloxysulfuron

Ͳ Na cucumber height SE = 0.01249
trifloxysulfuron

Ͳ Na lettuce biomass SE = 0.00061
trifloxysulfuron

Ͳ Na oat biomass SE = 0.00714
trifloxysulfuron

Ͳ Na onion biomass SE = 0.00473
trifloxysulfuron

Ͳ Na radish biomass SE = 0.00205
trifloxysulfuron

Ͳ Na ryegrass biomass SE = 0.00187
trifloxysulfuron

Ͳ Na soybean height SE = 0.01070
trifloxysulfuron

Ͳ Na tomato biomass SE = 0.01873
trifloxysulfuron

Ͳ Na carrot biomass VV = 0.00043
trifloxysulfuron

Ͳ Na corn biomass VV = 0.00571
trifloxysulfuron

Ͳ Na cucumber height VV = 0.00205
trifloxysulfuron

Ͳ Na lettuce biomass VV = 0.00014
trifloxysulfuron

Ͳ Na oat biomass VV = 0.02498
trifloxysulfuron

Ͳ Na onion height VV = 0.02319
trifloxysulfuron

Ͳ Na radish biomass VV = 0.00001
trifloxysulfuron

Ͳ Na ryegrass biomass VV = 0.00562
trifloxysulfuron

Ͳ Na soybean height VV = 0.01160
trifloxysulfuron

Ͳ Na tomato height VV > 0.04863

triflusulfuron

Ͳ methyl corn height SE > 0.5

triflusulfuron

Ͳ methyl cucumber height SE > 0.5

triflusulfuron

Ͳ methyl oilseed rape height SE = 0.152

triflusulfuron

Ͳ methyl onion height SE = 0.263

triflusulfuron

Ͳ methyl pea height SE = 0.395

### Page 163 of 318 Chemical name Species Effects
endpoints VV/SE Operand EC25 (lb a.i./A)

triflusulfuron

Ͳ methyl sorghum height SE > 0.125

triflusulfuron

Ͳ methyl soybean height SE > 0.5

triflusulfuron

Ͳ methyl sugar beet height SE > 0.5

triflusulfuron

Ͳ methyl tomato height SE > 0.5

triflusulfuron

Ͳ methyl wheat height SE = 0.391

triflusulfuron

Ͳ methyl corn biomass VV = 0.00054

triflusulfuron

Ͳ methyl cucumber height VV = 0.00088

triflusulfuron

Ͳ methyl oilseed rape biomass VV = 0.000087

triflusulfuron

Ͳ methyl onion biomass VV = 0.004

triflusulfuron

Ͳ methyl pea biomass VV = 0.00063

triflusulfuron

Ͳ methyl sorghum biomass VV = 0.00035

triflusulfuron

Ͳ methyl soybean height VV = 0.00087

triflusulfuron

Ͳ methyl sugar beet height VV > 0.0019

triflusulfuron

Ͳ methyl tomato biomass VV = 0.0011

triflusulfuron

Ͳ methyl wheat biomass VV = 0.0022

### Page 164 of 318 Appendix E. Distance to LOC for Vegetative Vigor Endpoints

The graphs in this section show the distance from the edge of the application to the LOC (1.0; where the EEC equals the IC 25 

### ) for vegetative vigor endpoints. Each species tested is included; not all chemicals tested the same species. Several species were tested for only a single chemical. Graphs are arranged by species such that three aerial application droplet size spectra are presented, followed by a graph for high boom ground application and a graph for low boom ground application. The ground applications use the AgDRIFT default droplet spectrum, fine to medium/coarse. The equations used are only validated to 1000 feet.

### Page 165 of 318 VV Radish ǦȋȌǣ

ǦȋȌǣ flazasulfuron(height), 1,000

foramsulfuron(biomass),

1,000

halosulfuron

Ͳ methyl(biomass), 1,000

imazasulfuron(surv), 11

mesosulfuron

Ͳ methyl(biomass), 333

orthosulfamuron(biomass),

1,000

prosulfuron(biomass), 163

sulfosulfuron(biomass),

1,000

trifloxysulfuron

Ͳ Na(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_VV

flazasulfuron(height), 1,000

foramsulfuron(biomass),

1,000

halosulfuron

Ͳ methyl(biomass), 1,000

imazasulfuron(surv), 7

mesosulfuron

Ͳ methyl(biomass), 212
orthosulfamuron(biomass),

807

prosulfuron(biomass), 106

sulfosulfuron(biomass),

1,000
trifloxysulfuron

Ͳ Na(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_VV

### Page 166 of 318 ǦȋȌǣ  flazasulfuron(height), 1,000

foramsulfuron(biomass),

972

halosulfuron

Ͳ methyl(biomass), 1,000

imazasulfuron(surv), 0

mesosulfuron

Ͳ methyl(biomass), 105

orthosulfamuron(biomass),

455

prosulfuron(biomass), 35

sulfosulfuron(biomass),

1,000

trifloxysulfuron

Ͳ Na(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_VV

### Page 167 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(height), 691

foramsulfuron(biomass),

419

halosulfuron

Ͳ methyl(biomass), 1,000

imazasulfuron(surv), 1

mesosulfuron

Ͳ methyl(biomass), 26

orthosulfamuron(biomass),

146

prosulfuron(biomass), 11

sulfosulfuron(biomass), 633

trifloxysulfuron

Ͳ Na(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_VV

flazasulfuron(height), 965

foramsulfuron(biomass),

603

halosulfuron

Ͳ methyl(biomass), 1,000

imazasulfuron(surv), 1

mesosulfuron

Ͳ methyl(biomass), 44

orthosulfamuron(biomass),

225

prosulfuron(biomass), 19

sulfosulfuron(biomass), 889

trifloxysulfuron

Ͳ Na(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_VV

### Page 168 of 318 VV Buckwheat ǦȋȌǣ

ǦȋȌǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_VV

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_VV

### Page 169 of 318 ǦȋȌǣ  imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_VV

### Page 170 of 318 ȋȌǣ

ȋȌǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_VV

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_VV

### Page 171 of 318 VV Flax Ǧȋ	Ȍǣ

Ǧȋ	Ȍǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_VV

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_VV

### Page 172 of 318 Ǧȋ	Ȍǣ  imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_VV

### Page 173 of 318 ȋ	Ȍǣ

ȋ	Ȍǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_VV

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_VV

### Page 174 of 318 VV Corn ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 711 chlorsulfuron(biomass),

783 flazasulfuron(biomass),

394 foramsulfuron(biomass), 0

halosulfuron

Ͳ methyl(biomass), 54 imazasulfuron(biomass), 0

iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 8 mesosulfuron

Ͳ methyl(biomass), 158 metsulfuron

Ͳ methyl(biomass), 615 orthosulfamuron(height),

55 primisulfuron

Ͳ methyl(biomass), 0 prosulfuron(biomass), 0

rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 61

thifensulfuron

Ͳ methyl(biomass), 26 triasulfuron(height), 16 trifloxysulfuron

Ͳ Na(biomass), 18 triflusulfuron

Ͳ methyl(biomass), 281 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

bensulfuron

Ͳ methyl(none), 0 chlorimuron

Ͳ ethyl(biomass),

444 chlorsulfuron(biomass), 487 flazasulfuron(biomass), 250 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass),

36 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 5 mesosulfuron

Ͳ methyl(biomass), 103 metsulfuron

Ͳ methyl(biomass),

385 orthosulfamuron(height), 37 primisulfuron

Ͳ methyl(biomass), 0 prosulfuron(biomass), 0 rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 40 thifensulfuron

Ͳ methyl(biomass), 18 triasulfuron(height), 11 trifloxysulfuron

Ͳ Na(biomass),

12 triflusulfuron

Ͳ methyl(biomass), 180

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 175 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none), 0 chlorimuron

Ͳ ethyl(biomass),

248 chlorsulfuron(biomass), 273
flazasulfuron(biomass), 130
foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass),

0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 0

mesosulfuron

Ͳ methyl(biomass), 33 metsulfuron

Ͳ methyl(biomass),

213 orthosulfamuron(height), 0

primisulfuron

Ͳ methyl(biomass), 0 prosulfuron(biomass), 0
rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 0

thifensulfuron

Ͳ methyl(biomass), 0 triasulfuron(height), 0
trifloxysulfuron

Ͳ Na(biomass), 0 triflusulfuron

Ͳ methyl(biomass),

85

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 176 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none), 0

chlorimuron

Ͳ ethyl(biomass), 67

chlorsulfuron(biomass), 75

flazasulfuron(biomass), 32

foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass),

3 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 1 mesosulfuron

Ͳ methyl(biomass), 10 metsulfuron

Ͳ methyl(biomass),

56 orthosulfamuron(height), 3 primisulfuron

Ͳ methyl(biomass),

0 prosulfuron(biomass), 0

rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 3

thifensulfuron

Ͳ methyl(biomass), 1 triasulfuron(height), 1

trifloxysulfuron

Ͳ Na(biomass), 1

triflusulfuron

Ͳ methyl(biomass),

21

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

bensulfuron

Ͳ methyl(none), 0 chlorimuron

Ͳ ethyl(biomass),

107 chlorsulfuron(biomass), 121
flazasulfuron(biomass), 53
foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass),

6 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 1

mesosulfuron

Ͳ methyl(biomass), 19 metsulfuron

Ͳ methyl(biomass),

90 orthosulfamuron(height), 6 primisulfuron

Ͳ methyl(biomass),

0 prosulfuron(biomass), 0
rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass),

1,000 sulfosulfuron(biomass), 6

thifensulfuron

Ͳ methyl(biomass), 3 triasulfuron(height), 2
trifloxysulfuron

Ͳ Na(biomass), 2 triflusulfuron

Ͳ methyl(biomass),

36

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_VV

### Page 177 of 318 VV Cucumber ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(height), 248 chlorimuron

Ͳ ethyl(height),

578 chlorsulfuron(biomass), 76 flazasulfuron(biomass),

160 foramsulfuron(height),

880 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 587 mesosulfuron

Ͳ methyl(biomass), 158 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass),

126 primisulfuron

Ͳ methyl(height), 1,000 prosulfuron(biomass), 0 rimsulfuron(biomass), 1 sulfometuron

Ͳ methyl ( R ) (height), 1,000 sulfometuron

Ͳ methyl(height), 1,000 sulfosulfuron(biomass), 11 thifensulfuron

Ͳ methyl(biomass), 361 triasulfuron(biomass), 492 trifloxysulfuron

Ͳ Na(height), 66 triflusulfuron

Ͳ methyl(height), 175 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_VV

bensulfuron

Ͳ methyl(height), 160 chlorimuron

Ͳ ethyl(height),

363 chlorsulfuron(biomass), 51 flazasulfuron(biomass),

104 foramsulfuron(height),

545 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 369 mesosulfuron

Ͳ methyl(biomass), 103 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 82 primisulfuron

Ͳ methyl(height), 767 prosulfuron(biomass), 0 rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (height), 790 sulfometuron

Ͳ methyl(height), 1,000 sulfosulfuron(biomass), 8 thifensulfuron

Ͳ methyl(biomass), 230 triasulfuron(biomass), 310 trifloxysulfuron

Ͳ Na(height), 44 triflusulfuron

Ͳ methyl(height), 114 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_VV

### Page 178 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(height), 71 chlorimuron

Ͳ ethyl(height),

199 chlorsulfuron(biomass), 0
flazasulfuron(biomass), 33 foramsulfuron(height),

307 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 203 mesosulfuron

Ͳ methyl(biomass), 33 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 18 primisulfuron

Ͳ methyl(height), 433 prosulfuron(biomass), 0
rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (height), 446 sulfometuron

Ͳ methyl(height), 1,000 sulfosulfuron(biomass), 0 thifensulfuron

Ͳ methyl(biomass), 117 triasulfuron(biomass), 167 trifloxysulfuron

Ͳ

Na(height), 0 triflusulfuron

Ͳ methyl(height), 40

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_VV

### Page 179 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(height),

18 chlorimuron

Ͳ ethyl(height), 51

chlorsulfuron(biomass), 4

flazasulfuron(biomass), 10

foramsulfuron(height), 88 halosulfuron

Ͳ methyl(biomass),

0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 52 mesosulfuron

Ͳ methyl(biomass), 10 metsulfuron

Ͳ methyl(biomass),

658 nicosulfuron(biomass), 8 primisulfuron

Ͳ methyl(height),

137 prosulfuron(biomass), 0

rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (height), 142 sulfometuron

Ͳ methyl(height),

1,000 sulfosulfuron(biomass), 1 thifensulfuron

Ͳ methyl(biomass), 28

triasulfuron(biomass), 42

trifloxysulfuron

Ͳ Na(height), 4 triflusulfuron

Ͳ methyl(height),

12

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_VV

Bensulfuron

Ͳ methyl, 31

chlorimuron

Ͳ ethyl(height),

84 chlorsulfuron(biomass), 8 flazasulfuron(biomass), 19 foramsulfuron(height),

138 halosulfuron

Ͳ methyl(biomass), 0

iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 86 mesosulfuron

Ͳ methyl(biomass), 19 metsulfuron

Ͳ methyl(biomass), 921 nicosulfuron(biomass), 14 primisulfuron

Ͳ methyl(height), 211 prosulfuron(biomass), 0 rimsulfuron(biomass), 1 sulfometuron

Ͳ methyl ( R ) (height), 219 sulfometuron

Ͳ methyl(height), 1,000 sulfosulfuron(biomass), 1 thifensulfuron

Ͳ methyl(biomass), 48

triasulfuron(biomass), 69 trifloxysulfuron

Ͳ

Na(height), 7

triflusulfuron

Ͳ methyl(height), 21

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_VV

### Page 180 of 318 VV Oat ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none),

0 chlorsulfuron(biomass), 23

flazasulfuron(biomass), 246 foramsulfuron(biomass),

152 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 8 mesosulfuron

Ͳ methyl(biomass), 175 metsulfuron

Ͳ methyl(biomass), 658 nicosulfuron(biomass), 23 orthosulfamuron(biomass),

0 primisulfuron

Ͳ methyl(biomass), 250 prosulfuron(biomass), 0

rimsulfuron(biomass), 220

sulfosulfuron(biomass), 86

triasulfuron(biomass), 0 trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_VV

bensulfuron

Ͳ methyl(none),

0 chlorsulfuron(biomass), 16

flazasulfuron(biomass), 158

foramsulfuron(biomass), 99 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 5 mesosulfuron

Ͳ methyl(biomass), 113 metsulfuron

Ͳ methyl(biomass), 411 nicosulfuron(biomass), 15 orthosulfamuron(biomass),

0 primisulfuron

Ͳ methyl(biomass), 161 prosulfuron(biomass), 0

rimsulfuron(biomass), 142

sulfosulfuron(biomass), 57

triasulfuron(biomass), 0 trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_VV

### Page 181 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none),

0
chlorsulfuron(biomass), 0

flazasulfuron(biomass), 70
foramsulfuron(biomass),

30 halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 0 mesosulfuron

Ͳ methyl(biomass), 40 metsulfuron

Ͳ methyl(biomass), 228
nicosulfuron(biomass), 0
orthosulfamuron(biomass),

0 primisulfuron

Ͳ methyl(biomass), 72
prosulfuron(biomass), 0

rimsulfuron(biomass), 59

sulfosulfuron(biomass), 0

triasulfuron(biomass), 0
trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_VV

### Page 182 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none),

0 chlorsulfuron(biomass), 1

flazasulfuron(biomass), 18

foramsulfuron(biomass), 10

halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1 mesosulfuron

Ͳ methyl(biomass), 12
metsulfuron

Ͳ methyl(biomass), 61

nicosulfuron(biomass), 1 orthosulfamuron(biomass),

0 primisulfuron

Ͳ methyl(biomass), 18 prosulfuron(biomass), 0

rimsulfuron(biomass), 15

sulfosulfuron(biomass), 5

triasulfuron(biomass), 0 trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_VV

bensulfuron

Ͳ methyl(none),

0 chlorsulfuron(biomass), 3

flazasulfuron(biomass), 31

foramsulfuron(biomass), 18
halosulfuron

Ͳ methyl(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1 mesosulfuron

Ͳ methyl(biomass), 21 metsulfuron

Ͳ methyl(biomass), 98 nicosulfuron(biomass), 2 orthosulfamuron(biomass),

0 primisulfuron

Ͳ methyl(biomass), 31 prosulfuron(biomass), 0

rimsulfuron(biomass), 27

sulfosulfuron(biomass), 9

triasulfuron(biomass), 0 trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_VV

### Page 183 of 318 VV Oilseed Rape ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(biomass), 1,000 chlorimuron

Ͳ ethyl(height),

1,000 chlorsulfuron(height),

1,000 metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass),

158 orthosulfamuron(biomass)

, 0

rimsulfuron(height), 1,000

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 thifensulfuron

Ͳ methyl(biomass), 1,000 triflusulfuron

Ͳ methyl(biomass), 1,000

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

bensulfuron

Ͳ methyl(biomass), 768
chlorimuron

Ͳ ethyl(height),

1,000 chlorsulfuron(height),

1,000
metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass),

103 orthosulfamuron(biomass)

, 0

rimsulfuron(height), 636

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 1,000
triflusulfuron

Ͳ methyl(biomass), 941

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 184 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(biomass),

433 chlorimuron

Ͳ ethyl(height), 1,000 chlorsulfuron(height)

, 1,000
metsulfuron

Ͳ methyl(height), 568 nicosulfuron(biomass),

33 orthosulfamuron(bio mass), 0 rimsulfuron(height),

359
sulfometuron

Ͳ methyl ( R ) (biomass), 942 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass),

1,000 triflusulfuron

Ͳ methyl(biomass),

528

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 185 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(biomass), 137 chlorimuron

Ͳ ethyl(height), 1,000 chlorsulfuron(height),

1,000 metsulfuron

Ͳ methyl(height), 198 nicosulfuron(biomass)

, 10 orthosulfamuron(biomass),

0 rimsulfuron(height),

107 sulfometuron

Ͳ methyl ( R ) (biomass), 401 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 440 triflusulfuron

Ͳ methyl(biomass), 179

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

bensulfuron

Ͳ methyl(biomass), 211 chlorimuron

Ͳ ethyl(height), 1,000 chlorsulfuron(height),

1,000 metsulfuron

Ͳ methyl(height), 298 nicosulfuron(biomass),

19 orthosulfamuron(bio mass), 0 rimsulfuron(height),

167 sulfometuron

Ͳ methyl ( R ) (biomass), 578 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 631 triflusulfuron

Ͳ methyl(biomass), 271

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_VV

### Page 186 of 318 VV Onion ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass), 394 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass), 587 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000 mesosulfuron

Ͳ methyl(biomass), 122 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 5 orthosulfamuron(biomass),

66 primisulfuron

Ͳ methyl(biomass), 305 prosulfuron(biomass), 421 rimsulfuron(biomass), 147 sulfometuron

Ͳ methyl ( R ) (biomass), 471 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass),

114 thifensulfuron

Ͳ methyl(biomass), 1,000 triasulfuron(height), 309 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 34 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_VV

bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass), 250 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass), 369 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000 mesosulfuron

Ͳ methyl(biomass), 80 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 3 orthosulfamuron(biomass),

44 primisulfuron

Ͳ methyl(biomass), 195 prosulfuron(biomass), 267 rimsulfuron(biomass), 96 sulfometuron

Ͳ methyl ( R ) (biomass), 298 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 75 thifensulfuron

Ͳ methyl(biomass), 1,000 triasulfuron(height), 198 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 23 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_VV

### Page 187 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none), 0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass),

130 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass), 203 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000 mesosulfuron

Ͳ methyl(biomass), 16 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 0 orthosulfamuron(biomass)

, 0

primisulfuron

Ͳ methyl(biomass), 94 prosulfuron(biomass), 140

rimsulfuron(biomass), 28 sulfometuron

Ͳ methyl ( R ) (biomass), 159 sulfometuron

Ͳ methyl(biomass), 747 sulfosulfuron(biomass), 13 thifensulfuron

Ͳ methyl(biomass), 790 triasulfuron(height), 96 trifloxysulfuron

Ͳ

Na(height), 0 triflusulfuron

Ͳ methyl(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_VV

### Page 188 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass), 32 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass), 52 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 840 mesosulfuron

Ͳ methyl(biomass), 8 metsulfuron

Ͳ methyl(biomass), 875 nicosulfuron(biomass), 0 orthosulfamuron(biomass),

4 primisulfuron

Ͳ methyl(biomass), 23

prosulfuron(biomass), 34 rimsulfuron(biomass), 9 sulfometuron

Ͳ methyl ( R ) (biomass), 40 sulfometuron

Ͳ methyl(biomass), 289 sulfosulfuron(biomass), 7 thifensulfuron

Ͳ methyl(biomass), 313 triasulfuron(height), 23 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 2

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_VV

bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass), 53 foramsulfuron(biomass), 0 halosulfuron

Ͳ methyl(biomass), 86 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000 mesosulfuron

Ͳ methyl(biomass), 14 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 1 orthosulfamuron(biomass),

7 primisulfuron

Ͳ methyl(biomass), 40

prosulfuron(biomass), 58 rimsulfuron(biomass), 17 sulfometuron

Ͳ methyl ( R ) (biomass), 66 sulfometuron

Ͳ methyl(biomass), 425 sulfosulfuron(biomass), 13 thifensulfuron

Ͳ methyl(biomass), 458 triasulfuron(height), 40 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 4

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_VV

### Page 189 of 318 VV Pea ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none),

0
chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000
metsulfuron

Ͳ methyl(biomass), 829

nicosulfuron(height), 0

orthosulfamuron(height),

194

rimsulfuron(biomass), 102

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 75
triflusulfuron

Ͳ methyl(biomass), 243

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_VV

bensulfuron

Ͳ methyl(none),

0 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 metsulfuron

Ͳ methyl(biomass), 515

nicosulfuron(height), 0

orthosulfamuron(height),

126

rimsulfuron(biomass), 67

sulfometuron

Ͳ methyl ( R ) (biomass), 801 sulfometuron

Ͳ methyl(biomass), 1,000 thifensulfuron

Ͳ methyl(biomass), 50 triflusulfuron

Ͳ methyl(biomass), 156

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_VV

### Page 190 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none),

0

chlorimuron

Ͳ ethyl(biomass), 1,000

chlorsulfuron(biomass),

1,000

metsulfuron

Ͳ methyl(biomass), 289

nicosulfuron(height), 0

orthosulfamuron(height),

48

rimsulfuron(biomass), 7

sulfometuron

Ͳ methyl ( R ) (biomass), 452

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 69

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_VV

### Page 191 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none),

0
chlorimuron

Ͳ ethyl(biomass), 545 chlorsulfuron(biomass),

1,000
metsulfuron

Ͳ methyl(biomass), 81

nicosulfuron(height), 0

orthosulfamuron(height),

13

rimsulfuron(biomass), 6

sulfometuron

Ͳ methyl ( R ) (biomass), 145
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 4
triflusulfuron

Ͳ methyl(biomass), 17

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_VV

bensulfuron

Ͳ methyl(none),

0

chlorimuron

Ͳ ethyl(biomass), 772 chlorsulfuron(biomass),

1,000
metsulfuron

Ͳ methyl(biomass), 129

nicosulfuron(height), 0

orthosulfamuron(height),

23

rimsulfuron(biomass), 11

sulfometuron

Ͳ methyl ( R ) (biomass), 223
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 8
triflusulfuron

Ͳ methyl(biomass), 30

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_VV

### Page 192 of 318 VV Ryegrass ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none), 0 flazasulfuron(biomass),

531 foramsulfuron(biomass)

, 152 halosulfuron

Ͳ methyl(biomass), 117 imazasulfuron(height),

0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000 metsulfuron

Ͳ methyl(biomass), 340 primisulfuron

Ͳ methyl(biomass), 144 prosulfuron(height),

150 sulfosulfuron(biomass),

114 triasulfuron(biomass),

586 trifloxysulfuron

Ͳ Na(biomass), 18

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_VV

bensulfuron

Ͳ methyl(none), 0 flazasulfuron(biomass),

334 foramsulfuron(biomass)

, 99 halosulfuron

Ͳ methyl(biomass), 77 imazasulfuron(height),

0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 850 metsulfuron

Ͳ methyl(biomass), 217 primisulfuron

Ͳ methyl(biomass), 94 prosulfuron(height), 97 sulfosulfuron(biomass),

75 triasulfuron(biomass),

368 trifloxysulfuron

Ͳ Na(biomass), 12

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_VV

### Page 193 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none), 0 flazasulfuron(biomass),

182 foramsulfuron(biomass ), 30
halosulfuron

Ͳ methyl(biomass), 14 imazasulfuron(height),

0
iodosulfuron

Ͳ methyl

Ͳ Na(height), 479
metsulfuron

Ͳ methyl(biomass), 108 primisulfuron

Ͳ methyl(biomass), 26

prosulfuron(height), 29

sulfosulfuron(biomass),

13 triasulfuron(biomass),

202 trifloxysulfuron

Ͳ Na(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_VV

### Page 194 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none), 0 flazasulfuron(biomass),

46 foramsulfuron(biomass),

10 halosulfuron

Ͳ methyl(biomass), 7 imazasulfuron(height), 0
iodosulfuron

Ͳ methyl

Ͳ Na(height), 157 metsulfuron

Ͳ methyl(biomass), 26 primisulfuron

Ͳ methyl(biomass), 9 prosulfuron(height), 10 sulfosulfuron(biomass),

7 triasulfuron(biomass),

52 trifloxysulfuron

Ͳ Na(biomass), 1

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_VV

bensulfuron

Ͳ methyl(none), 0 flazasulfuron(biomass),

76 foramsulfuron(biomass),

18 halosulfuron

Ͳ methyl(biomass), 13

imazasulfuron(height), 0

iodosulfuron

Ͳ methyl

Ͳ Na(height), 239 metsulfuron

Ͳ methyl(biomass), 45 primisulfuron

Ͳ methyl(biomass), 17

prosulfuron(height), 17

sulfosulfuron(biomass),

13 triasulfuron(biomass),

85 trifloxysulfuron

Ͳ Na(biomass), 2

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_VV

### Page 195 of 318 VV Soybean ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(biomass), 1,000 chlorimuron

Ͳ ethyl(biomass), 99 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass),

717 foramsulfuron(height), 118 halosulfuron

Ͳ methyl(biomass), 580 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 657 mesosulfuron

Ͳ methyl(biomass), 444 metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass), 0 orthosulfamuron(height),

193 primisulfuron

Ͳ methyl(height), 22 prosulfuron(biomass), 378 rimsulfuron(biomass), 104 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass),

691 thifensulfuron

Ͳ methyl(biomass), 1 triasulfuron(biomass), 318 trifloxysulfuron

Ͳ Na(height),

3 triflusulfuron

Ͳ methyl(height), 177

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_VV

bensulfuron

Ͳ methyl(biomass), 1,000 chlorimuron

Ͳ ethyl(biomass), 65 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass),

447 foramsulfuron(height), 77 halosulfuron

Ͳ methyl(biomass), 364 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 411 mesosulfuron

Ͳ methyl(biomass), 281 metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass), 0 orthosulfamuron(height),

125 primisulfuron

Ͳ methyl(height), 15 prosulfuron(biomass), 240 rimsulfuron(biomass), 68 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass),

431 thifensulfuron

Ͳ methyl(biomass), 0 triasulfuron(biomass), 203 trifloxysulfuron

Ͳ Na(height),

2 triflusulfuron

Ͳ methyl(height), 115 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_VV

### Page 196 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(biomass), 626 chlorimuron

Ͳ ethyl(biomass), 6 chlorsulfuron(biomass),

1,000 flazasulfuron(biomass),

250 foramsulfuron(height), 14 halosulfuron

Ͳ methyl(biomass), 200 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(height), 228 mesosulfuron

Ͳ methyl(biomass), 149 metsulfuron

Ͳ methyl(height), 1,000 nicosulfuron(biomass), 0 orthosulfamuron(height),

48 primisulfuron

Ͳ methyl(height), 0 prosulfuron(biomass), 123

rimsulfuron(biomass), 8 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass),

240 thifensulfuron

Ͳ methyl(biomass), 0 triasulfuron(biomass), 100 trifloxysulfuron

Ͳ

Na(height), 0 triflusulfuron

Ͳ methyl(height), 41

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_VV

### Page 197 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(biomass), 226 chlorimuron

Ͳ ethyl(biomass),

6 chlorsulfuron(biomass), 714 flazasulfuron(biomass), 67 foramsulfuron(height), 7 halosulfuron

Ͳ methyl(biomass), 52 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 60 mesosulfuron

Ͳ methyl(biomass), 37 metsulfuron

Ͳ methyl(height),

566 nicosulfuron(biomass), 0

orthosulfamuron(height), 13 primisulfuron

Ͳ methyl(height), 1 prosulfuron(biomass), 30 rimsulfuron(biomass), 6 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 64 thifensulfuron

Ͳ methyl(biomass), 0

triasulfuron(biomass), 24 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(height), 12

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_VV

bensulfuron

Ͳ methyl(biomass), 338 chlorimuron

Ͳ ethyl(biomass),

11 chlorsulfuron(biomass), 995 flazasulfuron(biomass), 108 foramsulfuron(height), 13 halosulfuron

Ͳ methyl(biomass), 84 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 98 mesosulfuron

Ͳ methyl(biomass), 61 metsulfuron

Ͳ methyl(height),

800 nicosulfuron(biomass), 0

orthosulfamuron(height), 23 primisulfuron

Ͳ methyl(height), 2 prosulfuron(biomass), 51 rimsulfuron(biomass), 12 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(biomass), 104 thifensulfuron

Ͳ methyl(biomass), 1 triasulfuron(biomass), 41 trifloxysulfuron

Ͳ Na(height),

1 triflusulfuron

Ͳ methyl(height), 21 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_VV

### Page 198 of 318 VV Sugar Beet ǦȋȌǣ

ǦȋȌǣ  bensulfuron

Ͳ methyl(height), 6

chlorimuron

Ͳ ethyl(biomass), 1,000
chlorsulfuron(biomass),

1,000

metsulfuron

Ͳ methyl(biomass), 1,000

nicosulfuron(biomass), 39

rimsulfuron(biomass), 98

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 1,000

triflusulfuron

Ͳ methyl(height), 80

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_VV

bensulfuron

Ͳ methyl(height), 4
chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000
metsulfuron

Ͳ methyl(biomass), 1,000

nicosulfuron(biomass), 26

rimsulfuron(biomass), 65

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000
sulfometuron

Ͳ methyl(biomass), 1,000
thifensulfuron

Ͳ methyl(biomass), 1,000
triflusulfuron

Ͳ methyl(height), 53

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_VV

### Page 199 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(height), 0

chlorimuron

Ͳ ethyl(biomass), 1,000

chlorsulfuron(biomass),

1,000

metsulfuron

Ͳ methyl(biomass), 1,000

nicosulfuron(biomass), 0

rimsulfuron(biomass), 5

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 1,000

triflusulfuron

Ͳ methyl(height), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_VV

### Page 200 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(height), 0

chlorimuron

Ͳ ethyl(biomass), 511 chlorsulfuron(biomass),

1,000

metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass),

2

rimsulfuron(biomass), 6

sulfometuron

Ͳ methyl ( R ) (biomass), 786

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 551

triflusulfuron

Ͳ methyl(height), 5

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_VV

bensulfuron

Ͳ methyl(height), 1 chlorimuron

Ͳ ethyl(biomass), 726 chlorsulfuron(biomass),

1,000 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass),

4 rimsulfuron(biomass),

11
sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 thifensulfuron

Ͳ methyl(biomass), 780 triflusulfuron

Ͳ methyl(height), 9

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_VV

### Page 201 of 318 VV Tomato ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(height), 1,000 chlorimuron

Ͳ ethyl(biomass), 1,000 chlorsulfuron(biomass),

1,000 foramsulfuron(biomass),

152 halosulfuron

Ͳ methyl(biomass), 0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000 mesosulfuron

Ͳ methyl(biomass), 391 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 85 primisulfuron

Ͳ methyl(height), 267 prosulfuron(biomass), 48 rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(height), 0 thifensulfuron

Ͳ methyl(biomass), 163 triasulfuron(biomass), 489 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 141

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_VV

bensulfuron

Ͳ methyl(height), 781 chlorimuron

Ͳ ethyl(biomass), 887 chlorsulfuron(biomass),

1,000 foramsulfuron(biomass), 99 halosulfuron

Ͳ methyl(biomass), 0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 940 mesosulfuron

Ͳ methyl(biomass), 248 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 56 primisulfuron

Ͳ methyl(height), 171 prosulfuron(biomass), 32 rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(height), 0 thifensulfuron

Ͳ methyl(biomass), 106 triasulfuron(biomass), 308 trifloxysulfuron

Ͳ Na(height),

0triflusulfuron

Ͳ methyl(biomass), 92

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_VV

### Page 202 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(height), 440

chlorimuron

Ͳ ethyl(biomass), 499 chlorsulfuron(biomass),

641 foramsulfuron(biomass),

30 halosulfuron

Ͳ methyl(biomass), 0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 528 mesosulfuron

Ͳ methyl(biomass), 129 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 0 primisulfuron

Ͳ methyl(height), 79 prosulfuron(biomass), 0

rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 628 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(height), 0 thifensulfuron

Ͳ methyl(biomass), 35 triasulfuron(biomass), 166 trifloxysulfuron

Ͳ

Na(height), 0 triflusulfuron

Ͳ methyl(biomass), 25

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_VV

### Page 203 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(height), 140 chlorimuron

Ͳ ethyl(biomass), 166 chlorsulfuron(biomass), 233 foramsulfuron(biomass), 10

halosulfuron

Ͳ methyl(biomass), 0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 179 mesosulfuron

Ͳ methyl(biomass), 31 metsulfuron

Ͳ methyl(biomass), 986 nicosulfuron(biomass), 5 primisulfuron

Ͳ methyl(height), 20 prosulfuron(biomass), 3 rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 227 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(height), 0 thifensulfuron

Ͳ methyl(biomass), 11 triasulfuron(biomass), 42 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 9

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_VV

bensulfuron

Ͳ methyl(height), 215 chlorimuron

Ͳ ethyl(biomass), 252 chlorsulfuron(biomass), 348
foramsulfuron(biomass), 18 halosulfuron

Ͳ methyl(biomass), 0 imazasulfuron(biomass), 0 iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 271 mesosulfuron

Ͳ methyl(biomass), 53 metsulfuron

Ͳ methyl(biomass), 1,000 nicosulfuron(biomass), 9 primisulfuron

Ͳ methyl(height), 34 prosulfuron(biomass), 5
rimsulfuron(biomass), 0 sulfometuron

Ͳ methyl ( R ) (biomass), 339 sulfometuron

Ͳ methyl(biomass), 1,000 sulfosulfuron(height), 0 thifensulfuron

Ͳ methyl(biomass), 19 triasulfuron(biomass), 69 trifloxysulfuron

Ͳ Na(height),

0 triflusulfuron

Ͳ methyl(biomass), 16

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_VV

### Page 204 of 318 VV Sorghum ǦȋȌǣ

ǦȋȌǣ chlorimuron

Ͳ ethyl(biomass), 642

chlorsulfuron(biomass),

1,000

nicosulfuron(biomass),

50

rimsulfuron(biomass),

371

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 1,000

triflusulfuron

Ͳ methyl(biomass), 424

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_VV

chlorimuron

Ͳ ethyl(biomass), 402
chlorsulfuron(biomass),

919
nicosulfuron(biomass),

34
rimsulfuron(biomass),

236

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 866

triflusulfuron

Ͳ methyl(biomass), 269

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_VV

### Page 205 of 318 ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass), 223

chlorsulfuron(biomass ), 517

nicosulfuron(biomass)

, 0

rimsulfuron(biomass),

120

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass),

1,000

thifensulfuron

Ͳ methyl(biomass), 487

triflusulfuron

Ͳ methyl(biomass), 141

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_VV

### Page 206 of 318 ȋȌǣ

ȋȌǣ chlorimuron

Ͳ ethyl(biomass), 59
chlorsulfuron(biomass ), 174
nicosulfuron(biomass),

3
rimsulfuron(biomass),

29

sulfometuron

Ͳ methyl ( R ) (biomass), 788 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 161

triflusulfuron

Ͳ methyl(biomass), 35

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_VV

chlorimuron

Ͳ ethyl(biomass), 95
chlorsulfuron(biomass ), 264
nicosulfuron(biomass),

5
rimsulfuron(biomass),

50

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 245

triflusulfuron

Ͳ methyl(biomass), 58

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_VV

### Page 207 of 318 VV Wheat ǦȋȌǣ

ǦȋȌǣ chlorimuron

Ͳ ethyl(biomass), 352

imazasulfuron(biomass),

0

mesosulfuron

Ͳ methyl(biomass), 0

nicosulfuron(biomass),

25

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 68

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_VV

chlorimuron

Ͳ ethyl(biomass), 224
imazasulfuron(biomass),

0

mesosulfuron

Ͳ methyl(biomass), 0

nicosulfuron(biomass),

17

sulfometuron

Ͳ methyl ( R ) (biomass), 1,000

sulfometuron

Ͳ methyl(biomass), 1,000

thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 45

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_VV

### Page 208 of 318 ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass), 113

imazasulfuron(biomas s), 0

mesosulfuron

Ͳ methyl(biomass), 0

nicosulfuron(biomass)

, 0

sulfometuron

Ͳ methyl ( R ) (biomass), 802

sulfometuron

Ͳ methyl(biomass),

1,000

thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 0

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_VV

### Page 209 of 318 ȋȌǣ

ȋȌǣ chlorimuron

Ͳ ethyl(biomass), 28

imazasulfuron(biomas s), 0

mesosulfuron

Ͳ methyl(biomass), 0

nicosulfuron(biomass)

, 1

sulfometuron

Ͳ methyl (

R ) (biomass), 319 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 4

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_VV

chlorimuron

Ͳ ethyl(biomass), 47 imazasulfuron(biomas s), 0

mesosulfuron

Ͳ methyl(biomass), 0 nicosulfuron(biomass)

, 3

sulfometuron

Ͳ methyl (

R ) (biomass), 467 sulfometuron

Ͳ methyl(biomass),

1,000 thifensulfuron

Ͳ methyl(biomass), 0

triflusulfuron

Ͳ methyl(biomass), 7

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_VV

### Page 210 of 318 VV Cabbage ǦȋȌǣ

ǦȋȌǣ flazasulfuron(biomass ), 571 halosulfuron

Ͳ methyl(biomass),

1,000 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 1,000

mesosulfuron

Ͳ methyl(biomass), 369

primisulfuron

Ͳ methyl(biomass), 341
prosulfuron(biomass),

163
sulfosulfuron(biomass ), 350
triasulfuron(biomass),

389

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_VV

flazasulfuron(biomass ), 359 halosulfuron

Ͳ methyl(biomass),

1,000 iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 1,000

mesosulfuron

Ͳ methyl(biomass), 235

primisulfuron

Ͳ methyl(biomass), 217 prosulfuron(biomass),

106

sulfosulfuron(biomass ), 223 triasulfuron(biomass),

247

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_VV

### Page 211 of 318 ǦȋȌǣ  flazasulfuron(biomass ), 197

halosulfuron

Ͳ methyl(biomass), 731

iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 1,000

mesosulfuron

Ͳ methyl(biomass), 120

primisulfuron

Ͳ methyl(biomass), 109

prosulfuron(biomass),

35

sulfosulfuron(biomass ), 112

triasulfuron(biomass),

128

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_VV

### Page 212 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass ), 51

halosulfuron

Ͳ methyl(biomass), 281

iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 602

mesosulfuron

Ͳ methyl(biomass), 29

primisulfuron

Ͳ methyl(biomass), 26

prosulfuron(biomass),

11

sulfosulfuron(biomass ), 27

triasulfuron(biomass),

31

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_VV

flazasulfuron(biomass ), 83

halosulfuron

Ͳ methyl(biomass), 414

iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 847

mesosulfuron

Ͳ methyl(biomass), 49 primisulfuron

Ͳ methyl(biomass), 45 prosulfuron(biomass),

19 sulfosulfuron(biomass ), 47 triasulfuron(biomass),

53

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_VV

### Page 213 of 318 VV Carrot ǦȋȌǣ

ǦȋȌǣ flazasulfuron(biomass),

1,000

foramsulfuron(biomas s), 329

orthosulfamuron(biomass),

1,000

primisulfuron

Ͳ methyl(biomass), 807

triasulfuron(biomass),

529

trifloxysulfuron

Ͳ Na(biomass), 319

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_VV

flazasulfuron(biomass ), 807

foramsulfuron(biomas s), 210

orthosulfamuron(biomass),

1,000

primisulfuron

Ͳ methyl(biomass), 502

triasulfuron(biomass),

333

trifloxysulfuron

Ͳ Na(biomass), 203

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_VV

### Page 214 of 318 ǦȋȌǣ  flazasulfuron(biomas s), 455

foramsulfuron(bioma ss), 104

orthosulfamuron(bio mass), 764

primisulfuron

Ͳ methyl(biomass), 282

triasulfuron(biomass)

, 181

trifloxysulfuron

Ͳ Na(biomass), 100

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_VV

### Page 215 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass ), 146

foramsulfuron(bioma ss), 25

orthosulfamuron(bio mass), 298

primisulfuron

Ͳ methyl(biomass), 78

triasulfuron(biomass),

46

trifloxysulfuron

Ͳ Na(biomass), 24

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_VV

flazasulfuron(biomass ), 225

foramsulfuron(bioma ss), 43

orthosulfamuron(bio mass), 438

primisulfuron

Ͳ methyl(biomass), 125

triasulfuron(biomass),

76

trifloxysulfuron

Ͳ Na(biomass), 42

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_VV

### Page 216 of 318 VV Lettuce ǦȋȌǣ

ǦȋȌǣ flazasulfuron(biomass)

, 229 foramsulfuron(biomas s), 21 halosulfuron

Ͳ methyl(biomass), 610 imazasulfuron(biomas s), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000 mesosulfuron

Ͳ methyl(biomass), 317 primisulfuron

Ͳ methyl(height), 750 prosulfuron(biomass),

128 sulfosulfuron(biomass ), 109 triasulfuron(height),

1,000 trifloxysulfuron

Ͳ Na(biomass), 891

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_VV

flazasulfuron(biomass)

, 148 foramsulfuron(biomas s), 14 halosulfuron

Ͳ methyl(biomass), 382 imazasulfuron(biomas s), 0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000 mesosulfuron

Ͳ methyl(biomass), 202 primisulfuron

Ͳ methyl(height), 467 prosulfuron(biomass),

84 sulfosulfuron(biomass ), 71 triasulfuron(height),

1,000 trifloxysulfuron

Ͳ Na(biomass), 552

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_VV

### Page 217 of 318 ǦȋȌǣ  flazasulfuron(biomass ), 63 foramsulfuron(biomas s), 0
halosulfuron

Ͳ methyl(biomass), 211 imazasulfuron(biomas s), 0
iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000
mesosulfuron

Ͳ methyl(biomass), 99 primisulfuron

Ͳ methyl(height), 261 prosulfuron(biomass),

19 sulfosulfuron(biomass ), 10 triasulfuron(height),

1,000 trifloxysulfuron

Ͳ Na(biomass), 311

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_VV

### Page 218 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass),

16 foramsulfuron(biomass),

1 halosulfuron

Ͳ methyl(biomass), 55 imazasulfuron(biomass),

0 iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000 mesosulfuron

Ͳ methyl(biomass), 24 primisulfuron

Ͳ methyl(height), 71

prosulfuron(biomass), 8

sulfosulfuron(biomass),

7

triasulfuron(height), 481

trifloxysulfuron

Ͳ Na(biomass), 89

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_VV

flazasulfuron(biomass), 28

foramsulfuron(biomass), 2

halosulfuron

Ͳ methyl(biomass), 90

imazasulfuron(biomass), 0

iodosulfuron

Ͳ methyl

Ͳ Na(height), 1,000

mesosulfuron

Ͳ methyl(biomass), 41 primisulfuron

Ͳ methyl(height), 114

prosulfuron(biomass), 15

sulfosulfuron(biomass), 12

triasulfuron(height), 686

trifloxysulfuron

Ͳ Na(biomass), 140

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_VV

### Page 219 of 318 VV Turnip ǦȋȌǣ

ǦȋȌǣ iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 476

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_VV

iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 300

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_VV

### Page 220 of 318 ǦȋȌǣ  iodosulfuron

Ͳ methyl

Ͳ

Na(biomass), 161

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_VV

### Page 221 of 318 ȋȌǣ

ȋȌǣ iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 40

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_VV_distance

iodosulfuron

Ͳ methyl

Ͳ Na(biomass), 67

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_VV_distance

### Page 222 of 318 VV Mung bean ǦȋȌǣ

ǦȋȌǣ  orthosulfamuron(bio mass), 194

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_VV

orthosulfamuron(bio mass), 126

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_VV

### Page 223 of 318 ǦȋȌǣ  orthosulfamuron(bio mass), 48

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_VV

### Page 224 of 318 ȋȌǣ

ȋȌǣ orthosulfamuron(bio mass), 13

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_VV

orthosulfamuron(bio mass), 23

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_VV

### Page 225 of 318 VV Rice ǦȋȌǣ

ǦȋȌǣ orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_VV

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_VV

### Page 226 of 318 ǦȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_VV

### Page 227 of 318 ȋȌǣ

ȋȌǣ orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_VV

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_VV

### Page 228 of 318 Appendix F. Distance to LOC Seedling Emergence Graphs

The graphs in this section show the distance from the edge of the application to the LOC (1.0; where the EEC equals the IC 25 

### ) for seedling emergence endpoints. Each species tested is included; not all chemicals tested the same species. Several species were tested with only a single chemical. Graphs are arranged by species such that three aerial application droplet siz spectra are presented, followed by a graph for high boom ground application and a graph for low boom ground application. The ground applications use the AgDRIFT default droplet spectrum, fine to medium/coarse. The equations used are only validated to 1000 feet.

SE Radish ǦȋȌǣ

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(height)

orthosulfamuron(biomass)

prosulfuron(biomass)

sulfosulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_SE

### Page 229 of 318 ǦȋȌǣ  flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(height)

orthosulfamuron(biomass)

prosulfuron(biomass)

sulfosulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_SE

### Page 230 of 318 ǦȋȌǣ

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(height)

orthosulfamuron(biomass)

prosulfuron(biomass)

sulfosulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_SE

### Page 231 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(height)

orthosulfamuron(biomass)

prosulfuron(biomass)

sulfosulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_SE

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(height)

orthosulfamuron(biomass)

prosulfuron(biomass)

sulfosulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ radish_SE

### Page 232 of 318 SE Buckwheat

ǦȋȌǣ

ǦȋȌǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_SE

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_SE

### Page 233 of 318 ǦȋȌǣ  imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_SE

### Page 234 of 318 ȋȌǣ

ȋȌǣ imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_SE

imazasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ buckwheat_SE

### Page 235 of 318 SE Flax Ǧȋ	Ȍǣ

Ǧȋ	Ȍǣ imazasulfuron(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_SE

imazasulfuron(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_SE

### Page 236 of 318 Ǧȋ	Ȍǣ  imazasulfuron(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_SE

### Page 237 of 318 ȋ	Ȍǣ

ȋ	Ȍǣ imazasulfuron(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_SE

imazasulfuron(bioma ss)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ flax_SE

### Page 238 of 318 SE Corn

ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none )

chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(biomass) flazasulfuron(biomass) foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass) orthosulfamuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass) rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass)

triasulfuron(biomass) trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_SE

bensulfuron

Ͳ methyl(none )

chlorimuron

Ͳ ethyl(biomass)
chlorsulfuron(biomass)
flazasulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass)
nicosulfuron(biomass)
orthosulfamuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)
rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height)
sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass)

triasulfuron(biomass)
trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_SE

### Page 239 of 318 ǦȋȌǣ

bensulfuron

Ͳ methyl(none )

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

orthosulfamuron(biomass)

primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass)

trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_SE

### Page 240 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none )

chlorimuron

Ͳ ethyl(biomass)
chlorsulfuron(biomass)
flazasulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass)
nicosulfuron(biomass)
orthosulfamuron(biomass)

primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)
rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height)
sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass)
trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_SE

bensulfuron

Ͳ methyl(none )

chlorimuron

Ͳ ethyl(biomass)
chlorsulfuron(biomass)
flazasulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass)

metsulfuron

Ͳ methyl(biomass)
nicosulfuron(biomass)
orthosulfamuron(biomass)

primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)
rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height)
sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass)
trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ corn_SE

### Page 241 of 318 SE Cucumber ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(height)
chlorsulfuron(biomass)
flazasulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)
rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)
trifloxysulfuron

Ͳ Na(height) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass)
flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_SE

### Page 242 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)

trifloxysulfuron

Ͳ Na(height) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_SE

### Page 243 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass)

sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)

trifloxysulfuron

Ͳ Na(height) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass)

flazasulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass) rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height) trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cucumber_SE

### Page 244 of 318 SE Oat ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none)

chlorsulfuron(biomass)

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(biomass) nicosulfuron(height)

orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_SE

bensulfuron

Ͳ methyl(none)

chlorsulfuron(biomass)

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(biomass) nicosulfuron(height)

orthosulfamuron(biomass)

primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_SE

### Page 245 of 318 ǦȋȌǣ

bensulfuron

Ͳ methyl(none)

chlorsulfuron(biomass)

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(height)

metsulfuron

Ͳ methyl(biomass) nicosulfuron(height)

orthosulfamuron(biomass)
primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass) triasulfuron(height)
trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_SE

### Page 246 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none)

chlorsulfuron(biomass)

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(height)

metsulfuron

Ͳ methyl(biomass) nicosulfuron(height)

orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfosulfuron(biomass)
thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_SE

bensulfuron

Ͳ methyl(none)

chlorsulfuron(biomass)

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(height)

metsulfuron

Ͳ methyl(biomass) nicosulfuron(height)

orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

rimsulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oat_SE

### Page 247 of 318 SE OilSeed Rape ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(height)

orthosulfamuron(biomass)

rimsulfuron(height)

sulfometuron

Ͳ methyl ( R ) (biomass)
sulfometuron

Ͳ methyl(biomass)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_SE

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(height)

orthosulfamuron(biomass)

rimsulfuron(height)

sulfometuron

Ͳ methyl ( R ) (biomass)
sulfometuron

Ͳ methyl(biomass)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_SE

### Page 248 of 318 ǦȋȌǣ

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(height)

orthosulfamuron(biomass)

rimsulfuron(height)

sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass)

thifensulfuron

Ͳ methyl(biomass)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_SE

### Page 249 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(height)

orthosulfamuron(biomass)

rimsulfuron(height)

sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass)

thifensulfuron

Ͳ methyl(biomass)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_SE

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(height)

orthosulfamuron(biomass)

rimsulfuron(height)

sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ oilseed rape_SE

### Page 250 of 318 SE Onion ǦȋȌǣ

ǦȋȌǣ  bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(height) nicosulfuron(height) orthosulfamuron(height) primisulfuron

Ͳ methyl(height)
prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_SE

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)
iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(height) nicosulfuron(height) orthosulfamuron(height) primisulfuron

Ͳ methyl(height)

prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_SE

### Page 251 of 318 ǦȋȌǣ

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

flazasulfuron(biomass)

foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(height) nicosulfuron(height)

orthosulfamuron(height) primisulfuron

Ͳ methyl(height) prosulfuron(height)

rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_SE

### Page 252 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(height) nicosulfuron(height) orthosulfamuron(height) primisulfuron

Ͳ methyl(height) prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_SE

bensulfuron

Ͳ methyl(height)

chlorimuron

Ͳ ethyl(height) chlorsulfuron(biomass) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) metsulfuron

Ͳ methyl(height) nicosulfuron(height) orthosulfamuron(height) primisulfuron

Ͳ methyl(height) prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ onion_SE

### Page 253 of 318 SE Pea ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(none)

orthosulfamuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) thifensulfuron

Ͳ methyl(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(none)

orthosulfamuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass)

thifensulfuron

Ͳ methyl(biomass)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_SE

### Page 254 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(none)

orthosulfamuron(bio mass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass)
sulfometuron

Ͳ methyl(biomass)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_SE

### Page 255 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(none)

orthosulfamuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass)
sulfometuron

Ͳ methyl(biomass)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(none)

orthosulfamuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (biomass)

sulfometuron

Ͳ methyl(biomass)

thifensulfuron

Ͳ methyl(biomass)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ pea_SE

### Page 256 of 318 SE Ryegrass ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(none)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass) imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) metsulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_SE

bensulfuron

Ͳ methyl(none)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) metsulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(height)
prosulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)
triasulfuron(height)

trifloxysulfuron

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_SE

### Page 257 of 318 ǦȋȌǣ

bensulfuron

Ͳ methyl(none)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

metsulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_SE

### Page 258 of 318 ȋȌǣ

ȋȌǣ bensulfuron

Ͳ methyl(none)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) metsulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_SE

bensulfuron

Ͳ methyl(none)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(biomass)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(biomass) metsulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(biomass)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ ryegrass_SE

### Page 259 of 318 SE Soybean ǦȋȌǣ

ǦȋȌǣ  Bensulfuron

Ͳ methyl

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(height) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(height) nicosulfuron(biomass) orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass) trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_SE

Bensulfuron

Ͳ methyl
chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(height) flazasulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(height) nicosulfuron(biomass) orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass) trifloxysulfuron

Ͳ Na(height) triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_SE

### Page 260 of 318 ǦȋȌǣ  Bensulfuron

Ͳ methyl chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(height)

flazasulfuron(biomass)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass)

metsulfuron

Ͳ methyl(height) nicosulfuron(biomass)

orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height)

prosulfuron(height)

rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass) triasulfuron(biomass)

trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_SE

### Page 261 of 318 ȋȌǣ

ȋȌǣ  bensulfuron

Ͳ methyl(biomass) chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(height) flazasulfuron(biomass) foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(height) nicosulfuron(biomass) orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height) prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height) thifensulfuron

Ͳ methyl(biomass)

triasulfuron(biomass) trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height) 0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_SE

bensulfuron

Ͳ methyl(biomass)

chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(height) flazasulfuron(biomass) foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(biomass) mesosulfuron

Ͳ methyl(biomass)

metsulfuron

Ͳ methyl(height) nicosulfuron(biomass) orthosulfamuron(biomass) primisulfuron

Ͳ methyl(height)

prosulfuron(height) rimsulfuron(height) sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) sulfosulfuron(height)

thifensulfuron

Ͳ methyl(biomass)

triasulfuron(biomass) trifloxysulfuron

Ͳ Na(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ soybean_SE

### Page 262 of 318 SE Sugar Beet ǦȋȌǣ

ǦȋȌǣ bensulfuron

Ͳ methyl(biomass)
chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)
sulfometuron

Ͳ methyl(height)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_SE

bensulfuron

Ͳ methyl(biomass) chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height) sulfometuron

Ͳ methyl(height) thifensulfuron

Ͳ methyl(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_SE

### Page 263 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(biomass)

chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

thifensulfuron

Ͳ methyl(biomass)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_SE

### Page 264 of 318 ȋȌǣ

ȋȌǣ  bensulfuron

Ͳ methyl(biomass)
chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)
sulfometuron

Ͳ methyl(height)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_SE

bensulfuron

Ͳ methyl(biomass)
chlorimuron

Ͳ ethyl(height)

chlorsulfuron(biomass)

metsulfuron

Ͳ methyl(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)
sulfometuron

Ͳ methyl(height)
thifensulfuron

Ͳ methyl(biomass)
triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sugar beet_SE

### Page 265 of 318 SE Tomato ǦȋȌǣ

ǦȋȌǣ  bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass) rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(biomass) foramsulfuron(biomass) halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass) rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_SE

### Page 266 of 318 ǦȋȌǣ  bensulfuron

Ͳ methyl(none) chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(biomass)

foramsulfuron(biomass) halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)

rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_SE

### Page 267 of 318 ȋȌǣ

ȋȌǣ  bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass) chlorsulfuron(biomass) foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height) imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass) rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_SE

bensulfuron

Ͳ methyl(none)

chlorimuron

Ͳ ethyl(biomass)
chlorsulfuron(biomass)
foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)
imazasulfuron(biomass) iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(biomass) metsulfuron

Ͳ methyl(biomass) nicosulfuron(biomass) primisulfuron

Ͳ methyl(biomass) prosulfuron(biomass)
rimsulfuron(biomass) sulfometuron

Ͳ methyl ( R ) (biomass) sulfometuron

Ͳ methyl(biomass) sulfosulfuron(biomass) thifensulfuron

Ͳ methyl(biomass) triasulfuron(height) trifloxysulfuron

Ͳ

Na(biomass) triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ tomato_SE

### Page 268 of 318 SE Sorghum ǦȋȌǣ

ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_SE

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_SE

### Page 269 of 318 ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomas s)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_SE

### Page 270 of 318 ȋȌǣ

ȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_SE

chlorimuron

Ͳ ethyl(biomass)

chlorsulfuron(biomass)

nicosulfuron(biomass)

rimsulfuron(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ sorghum_SE

### Page 271 of 318 SE Wheat ǦȋȌǣ

ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_SE

chlorimuron

Ͳ ethyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_SE

### Page 272 of 318 ǦȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_SE

### Page 273 of 318 ȋȌǣ

ȋȌǣ  chlorimuron

Ͳ ethyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_SE

chlorimuron

Ͳ ethyl(biomass)

imazasulfuron(height)

mesosulfuron

Ͳ methyl(biomass)

sulfometuron

Ͳ methyl ( R ) (height)

sulfometuron

Ͳ methyl(height)

triflusulfuron

Ͳ methyl(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ wheat_SE

### Page 274 of 318 SE Cabbage ǦȋȌǣ

ǦȋȌǣ flazasulfuron(biomass)

halosulfuron

Ͳ methyl(height)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass)
primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

sulfosulfuron(biomass )

triasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_SE

flazasulfuron(biomass)

halosulfuron

Ͳ methyl(height)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

sulfosulfuron(biomass )

triasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_SE

### Page 275 of 318 ǦȋȌǣ

flazasulfuron(biomas s)

halosulfuron

Ͳ methyl(height)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass)

primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

sulfosulfuron(biomas s)

triasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_SE

### Page 276 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass )

halosulfuron

Ͳ methyl(height)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass)

primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

sulfosulfuron(biomass )

triasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_SE

flazasulfuron(biomass )

halosulfuron

Ͳ methyl(height)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(biomass) primisulfuron

Ͳ methyl(biomass)

prosulfuron(biomass)

sulfosulfuron(biomass )

triasulfuron(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ cabbage_SE

### Page 277 of 318 SE Carrot ǦȋȌǣ

ǦȋȌǣ flazasulfuron(biomass )

foramsulfuron(bioma ss)

orthosulfamuron(bio mass)

primisulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_SE

flazasulfuron(biomass )

foramsulfuron(bioma ss)

orthosulfamuron(bio mass)

primisulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_SE

### Page 278 of 318 ǦȋȌǣ  flazasulfuron(biomass )

foramsulfuron(bioma ss)

orthosulfamuron(bio mass)

primisulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_SE

### Page 279 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(biomass)

foramsulfuron(biomas s)

orthosulfamuron(bio mass)

primisulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_SE

flazasulfuron(biomass)

foramsulfuron(biomas s)

orthosulfamuron(bio mass)

primisulfuron

Ͳ methyl(biomass)

triasulfuron(height)

trifloxysulfuron

Ͳ Na(height)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ carrot_SE

### Page 280 of 318 SE Lettuce ǦȋȌǣ

ǦȋȌǣ  flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(height)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_SE

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)
imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) primisulfuron

Ͳ methyl(height)
prosulfuron(biomass)

sulfosulfuron(height)

triasulfuron(height)
trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_SE

### Page 281 of 318 ǦȋȌǣ  flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height)

mesosulfuron

Ͳ methyl(height)
primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(height)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_SE

### Page 282 of 318 ȋȌǣ

ȋȌǣ flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)

imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) primisulfuron

Ͳ methyl(height)

prosulfuron(biomass)

sulfosulfuron(height)

triasulfuron(height)

trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_SE

flazasulfuron(none)

foramsulfuron(biomass)

halosulfuron

Ͳ methyl(height)
imazasulfuron(biomass)

iodosulfuron

Ͳ methyl

Ͳ Na(height) mesosulfuron

Ͳ methyl(height) primisulfuron

Ͳ methyl(height)
prosulfuron(biomass)

sulfosulfuron(height)

triasulfuron(height)
trifloxysulfuron

Ͳ

Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ lettuce_SE

### Page 283 of 318 SE Turnip ǦȋȌǣ

ǦȋȌǣ  iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_SE

iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_SE

### Page 284 of 318 ǦȋȌǣ  iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_SE

### Page 285 of 318 ȋȌǣ

ȋȌǣ  iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_SE

iodosulfuron

Ͳ methyl

Ͳ Na(biomass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ turnip_SE

### Page 286 of 318 SE Mung bean ǦȋȌǣ

ǦȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_SE

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_SE

### Page 287 of 318 ǦȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_SE

### Page 288 of 318 ȋȌǣ

ȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_SE

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ mung bean_SE

### Page 289 of 318 SE Rice ǦȋȌǣ

ǦȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_SE

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_SE

### Page 290 of 318 ǦȋȌǣ  orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_SE_distance fr

### Page 291 of 318 ȋȌǣ

ȋȌǣ orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_SE

orthosulfamuron(bio mass)

0 200 400 600 800 1000 1200

distance from EOF (ft) 

# Tox Array Ͳ rice_SE

### Page 292 of 318 Appendix G. Audrey III Equation Documentation

The PRZM time series output file (‘ZTS) contains the storm related inputs used in Audrey
III. As it is currently formatted, a daily value is put out for each parameter in cumulative
mode. That is, output is a cumulative running total for that variable. The parameters of
interest for calculating the runoff depth where the units are cm for each event:

.a ܦ ௜ 

### ܨܴܷܰ ൌ ௜ 

### .b ܯܴ ௜ 

### ܺܮܨܴ ൌ ௜



### .c ܧܴ ௜ 

### ܺܮܨܧ ൌ ௜ 

### d. ܹ ௜ 

### ൌ ܴܲܥܲ ௜



### where D is the depth of runoff for the event in centimeters, equivalent to the RUNF in the PRZM zts file, RM i 

### is the mass of pesticide for runoff on day I in kg·ha -1 

### , and is the RFLX in the PRZM zts file, RE is the mass of pesticide on eroded sediment on day, in kg·ha -1



### , and is the EFLX variable in the zts file, and W i 

### is the depth of precipitation in cm on day i, and is the PRCP in the PRZM output. RUNF, RFLX, EFLX, and PRCP are PRZM output parameters in the time series output file.

GEOMETRY OF THE PESTICIDE EXPOSURE ZONE 2) The area of the plant exposure zone (PEZ) is determined by the length of the side of the
field and width of the zone where overland flow is maintained. For example for a square
10 ha field, the length of the side of field, L PEZ 

### :

a. ܮ ௉ா௓ 

### ൌ ට ͳͲ݄ܽ ቀ ଵ଴଴଴଴௠ మ

௛௔ 

### ቁ

ൌ ξ ͳͲͲͲͲͲ݉ ଶ 

### ൌ ͵ͳ͸Ǥʹ݉

3) Overland flow can be maintained for 50 to 300 feet before a concentrated flow regime set
in. Once concentrated flow moves the water relatively rapidly through rill or gulleys, it
presents little opportunity for exposure for terrestrial plants. For the purposes of this
example, we will assume 50 feet = 15.2 m Therefore, the area of the Plant Exposure Zone
(PEZ) in square meters is equivalent to the zone at the edge of the field where overland

flow is maintained:

a. ܣ ௉ா௓ 

### ൌ ܮ ௉ா௓ 

### ݔܹ ௉ா௓ 

### ൌ ͵ͳ͸Ǥʹ݉ݔͳͷǤʹ݉ ൌ Ͷ ͅͳͻ݉ ଶ



### b.
4) For the purpose of this assessment, the VW PEZ 

### will partition into three portions, one part
continues to runoff past the edge of the PEZ as concentrated flow and enters stream, pond
or other water body, the second part infiltrates beyond the bottom of the Plant Exposure
Volume in the PEZ, and the third part is retained in the PEV. This third part is the portion
that results in exposure to terrestrial plants. The total volume of the PEV is the area of the
PEV times the depth of soil in the PEV, D PEV 

### . Since the majority of water taken up by
plants is from the top 6 inches of soil, the D PEV 

### is assumed to be 6 in § 15 cm=0.15m.

a. ܸ ௉ா௓ 

### ൌ ܣ ௉ா௓ 

### ܦݔ ௉ா௏ 

### ൌ Ͷ ͅͳͻ݉ ଶ 

### ݔͲǤͳͷ݉ ൌ ͹ʹʹǤ ݉ͅ ଷ



### HYDROLOGY

### Page 293 of 318 1) To get the total mass of pesticide and water coming onto the PEZ, we need to account for
the areas of the treated field (for the volume of runoff water, mass of pesticide in runoff
and pmass of pesticide on eroded sediment:

.a ܴ ௜ 

### ܦ ൌ ௜ 

### ܣ כ ௗ௙௜௘௟


### b. ܲ ௜ 

### ൌ ܹ ௜ 

### כ ܣ ௉ா௓



### where

R i 

### = runoff flow from treated field (PRZM time series file) (m 3 

### )

P i 

### = precipitation onto PEZ (PRZM time series file) (m 3 

### )

2) The total volume in the PEZ can also be expressed as :

a. ܸ ௉ா௓ 

### ൌ ܸ ௦௢௜௟ 

### ൅ ܸ ௪௔௧௘௥


### b. ߠ ൌ ௏ ೢೌ೟೐ೝ

௏ ುಶೋ



### c. ܸ ௪௔௧௘௥ 

### ൌ ߠܸ ௉ா௓ 

### 3) The flow balance in the PEZ is:

a. ܴ ௜ 

### ൅ ܲ ௜ 

### ൌ ܫ ௜ 

### ൅ ܳ ௜ 

### ൅ ߠ ௜ 

### ܸ ௉ா௓



### where

I i 

### = leaching from PEZ below the root extraction zone (m 3 

### ) Q i 

### = runoff flow from PEZ (m 3 

### )

ș i 

### = volumetric water content of soil (m 3 

### /m 3 

### )

V PEZ 

### = volume of PEZ (m 3 

### )



## As water will always be in the PEZ, ș should always be at or above THEWP, or the wilting point (m 3 

## /m 3 

## ). ș should always be at or below THEFC, or the field capacity (m 3 

## /m 3 

## ). When runoff and precipitation enter the mixing cell, the amount of water entering (R+P) plus the amount present from the previous day is compared to the THEFC. If it is greater, than ș is set to THEFC and the remainder is evaluated for runoff from the PEZ (Q) and leaching from the PEZ (I). If R and P are 0, and the amount from the previous day is greater than the wilting point, ș is set to THEWP and the water leaves the PEZ as leachate (I).

If Ĭ is set to THEFC and additional water is available for runoff, Q is calculated using the following algorithm

4) To get the volume of each runoff event in liters R i 

### , multiply the storm depth by the area of
the field (10 hectares) and convert the units:

a. ܴ ௜ 

### ൌ ቀ ஽ ೔ ௖௠

ଵ 

### ቁ ቀ ଵ௠

ଵ଴଴௖௠ 

### ቁ ቀ ଵ଴௛௔

ଵ 

### ቁ ቀ ଵ଴଴଴଴௠ మ

௛௔ 

### ቁ ቀ ଵ଴଴଴௅

ଵ௠ య 

### ቁ ൌ ͳͲ ଺ 

### ܦ ௜

### Page 294 of 318 5) The total volume of water in liters for each rainfall event that enters the PEZ in the volume
of runoff from the field plus the precipitation that falls directly on the PEZ. This volume

is:

a. ܸܲ ሺ௜ሻ 

### ൌܲ ௜ 

### ቀ ଵ௠

ଵ଴଴௖௠ 

### ቁ ܣ

௉ா௓ 

### The water capacity of the PEV, WC PEV 

### , is the available water capacity of the soil multiplied volume of the PEV. The available water capacity of the soil is the difference between field capacity and the wilting point water capacity of the soil. These two parameters are PRZM inputs THEFC 2 

### and THEWP, respectively. The available water capacity varies from soil to soil, but can be calculated for each scenario by looking up THEFC and THEWP in the PRZM input file. Units for THEFC and THEWP and V water 

### /V soil



### . .b ܹܲܧܪܶ െ ܥܨܧܪܶ ൌ ܥܹܣ

6) For the Kansas sorghum scenario used in this example has a Dennis silt loam soil where
THEFC = 0.247 and THEWP = 0.097, the WC PEZ 

### is:

a. ܹܥ ௉ா௓ 

### ൌ ܸ ௉ா௓ 

### ܣݔܹܥ ൌ ͹ʹʹǤ ݉ͅ ଷ 

### ݔ ሺ ͲǤʹͶ͹ െ ͲǤͲͻ͹ ሻ ൌ ͳͲ ͅǤͳ݉ ଷ



### 7) For each rainfall event, a portion of the runoff will infiltrate into the soil in the PEZ. The
amount that infiltrates is dependent on the curve number, the curve number associated with
each scenario can be associated with the Hydrologic Group of the soil, which are a labeled
A through D. The Dennis silt loam soil is Hydrologic Group C and the curve number used
for during the cropping season is 86. Note that the equation was developed with depth in
inches, so TD i 

### must be converted for the calculation. The curve number equation is:

a. ܳ ൌ ʹǤͷͶ ቀ ೅ವ ೔

మǤఱర ି଴Ǥଶௌቁ మ
ቀ ೅ವ ೔

మǤఱర ା଴Ǥ଼ௌቁ 

### , where

b. ܵ ൌ ଵ଴଴଴

஼ே 

### െ ͳͲ

c. Where Q is the runoff depth from the PEZ. Note that if the depth in inches is less than
0.2S, than the numerator in equation 10a is negative. This implies that all the water is
absorbed on the PEZ and nothing runs off. Q is set to zero when this occurs.
d. If the term in parentheses in the numerator in 10a is a negative number, it means that
the runoff event is less than the capacity of the soil to absorb it and the runoff of the
PEZ will be zero, so

e. ݂݅ ቀ ்஽ ೔

ଶǤହସ 

### ൐ ͲǤʹܵቁ ݐ݄݁݊ܳ ൌ ʹǤͷͶ ቀ ೅ವ ೔

మǤఱర ି଴Ǥଶௌቁ మ
ቀ ೅ವ ೔

మǤఱర ା଴Ǥ଼ௌቁ 

### ǡ ݈݁ݏ݁ܳ ൌ Ͳ

f. I is then calculated by I = R + P - Q - ȣ Vp

PESTICIDE LOADINGS to the PEZ

2 THEFC stands for theta at field capacity, THEW P stands for theta at the wilting point. Theta ( lj ) is the symbol used for volumetric soil water content by soil scientists.

### Page 295 of 318 Pesticides can be loaded onto the PEZ from three sources, spray drift, dissolved in runoff coming from the adjacent treated field, and adsorbed onto eroded sediment coming from the adjacent treated field. Spray drift deposition curves for 9 different application methods were estimated using AgDrift version 2.1.1. Those 9 methods are in Table 1.

Table 1. Spray drift application methods simulated in Audrey III

Method Use aerial, very fine to fine spray ultralow volume applications (ULV) aerial, fine to medium spray default aerial spray aerial, medium to coarse spray mitigation, spray quality restricted on label aerial, coarse to very coarse

spray mitigation, spray quality restricted on label

air blast, normal orchard most orchards and vineyard applications air blast, sparse orchard dormant sprays, young/non-bearing orchards, tall orchards (pecans) ground spray – high boom default ground spray ground spray – low boom pre- emergent sprays, mitigation practice

Spray deposition can be calculated in three ways, the application rate is assumed for deposition on the PEZ at the field edge. The point deposition at the far edge of the PEZ can be interpolated from the appropriate deposition curve, depending on the application type. The mean deposition across the PEZ is calculated by numerically integrating the deposition curve across the PEZ width using the trapezoidal rule. 8) The mass of pesticide in runoff for the whole PEZ is mass of pesticide in runoff in kg·ha -1



### from the treated field, RM i 

### , e(quation 1b) times the area of the treated field, AFIELD. The
area of the treated field is a PRZM input variable, and is usually set to the default value of

10 ha.

.a ܯܲ ௜ 

### ܯܴ ൌ ௜ 

### ܦܮܧܫܨܣ ൈ

9) The mass of pesticide on eroded sediment for the whole PEZ is mass of pesticide on
sediment in kg·ha -1 

### from the treated field, RE i 

### , (equation 1c) times the area of the treated
field, A. The area of the treated field is a PRZM input variable, and is usually set to the

default value of 10 ha.

.a ܯܧ ௜ 

### ܧܴ ൌ ௜ 

### ܦܮܧܫܨܣ ൈ

Plant Exposure in the PEZ The toxicity endpoints in the PEZ are in units of mass per unit area, kg·ha -1 

### , or lb·acre -1 

### , so the exposure estimates need to be in the same units. In order to estimate the plant EECs, we need to account for the degradation of the pesticide already in the PEZ, add mass from spray drift, erosion, and runoff loadings, and subtract the mass of pesticide lost with runout of the PEZ and leaching

below the PEZ. 10) The mass entering the PEZ during storm events:
a. Mf = Mrunoff + Merosion (PRZM time series file)
b. Mt = Mf + Mspray drift = Mp + Me + Mo (kg)

c. Where:

Mf is the mass carried onto the PEZ with storm runoff

### Page 296 of 318 Mrunoff is mass of pesticide dissolved in runoff form the treated field Merosion is the mass of pesticide adsorbed to sediment in the runoff Mspray drift is the mass of pesticide which drifts onto the PEZ from the treated field Mp is the mass of pesticide in the PEZ at the start of a time step Me is the mass of pesticide which is removed from the PEZ through leaching, and Mo is the mass of pesticide removed in runoff out of the PEZ In Audrey III these masses are all in kilograms Assume that new mass MT enters as an instantaneous pulse at time zero (i.e., at the beginning of each time step). Using equations 6.1, 6.2, 6.8, 6.9, and 6.16 from PRZM manual and rearranging and combining yields (similar to equation 6.20 in PRZM manual) the following mass balance description:

11) ௗሺ஼ ೢ ሺఏା௄ ೏ ఘ ೞ ሻሻ

ௗ௧ 

### ൌ ெ ೅ǡబ ఋ ሺ ௧ ሻ

஺ο௭ 

### െ ቀ ூାொ

஺ο௭ 

### ൅ ݇ܭ ௗ 

### ߩ ௦ 

### ൅ ݇ߠቁ ܥ

௪


### a. Where

C w 

### = dissolved concentration in the PEZ (kg/m 3 

### )

K d 

### = sorption coefficient (m 3 

### /kg)

ɏ s = soil bulk density (kg/m 3 

### ) A = area of PEZ (m 2 

### )

ȟ z = depth of PEZ (m) k = aerobic soil metabolism rate constant (d -1 

### )
12) Assuming ȣ + K d 

### ɏ s 

### over the course of a day is constant,

a. ௗሺ஼ ೢ ሻ

ௗ௧ 

### ൅ ቀ ூାொ
ሺ ఏା௄ ೏ ఘ ೞ ሻ ஺ο௭ 

### ൅ ݇ቁ ܥ

௪ 

### ൌ ெ ೅ǡబ ఋ ሺ ௧ ሻ

ሺ ఏା௄ ೏ ఘ ೞ ሻ ஺ο௭ 

### 13) The solution of which is:

a. ܥ
௪ 

### ൌ ெ ೅ǡబ ሺ ఏା௄ ೏ ఘ ೞ ሻ ஺ο௭ 

### ݁ ି൬ ಺శೂ ൫ ഇశ಼ ೏ ഐ ೞ ൯ ಲο೥ ା௞൰௧



### 14) The quantity ሺ ߠ൅ܭ ௗ 

### ߩ ௦ 

### ሻ ܣοݖ is assumed not to change during a time step. Thus we can
define the mass (M T 

### ) in the PEZ at any point during the time step as:

a. ܯ ் 

### ൌ ܯ ்ǡ଴ 

### ݁ ି൬ ಺శೂ ൫ ഇశ಼ ೏ ഐ ೞ ൯ ಲο೥ ା௞൰௧



### 15) And in general:

a. ܥ
௪ 

### ൌ ெ ೅ ሺ ఏା௄ ೏ ఘ ೞ ሻ ஺ο௭ 

### 16) Now define:

a. ܭ ଵ 

### ൌ ூାொ
ሺ ఏା௄ ೏ ఘ ೞ ሻ ஺ο௭ 

### ൅ ݇ (units = d -1 

### )

17) so that:

a. ܯ ் 

### ൌ ܯ ்ǡ଴ 

### ݁ ି௄ భ ௧



### 18) For example at the end of a time step of unit duration:

a. ܯ ்ǡଵ 

### ൌ ܯ ்ǡ଴ 

### ݁ ି௄ భ


### 19) The average mass of pesticide in the PEZ during the course of a time step can be
calculated by integration:

a. ܯ ෩ ் 

### ൌ ׬ ெ ೅ǡబ ௘ ష಼ భ ೟ ೟ మ
೟ భ ௗ௧

௧ మ ି௧ భ

### Page 297 of 318 b. ൌ ቂ ଵ

௧ భ ି௧ మ ெ ೅ǡబ

௄ భ 

### ݁ ି௄ భ ௧ మ 

### ቃെቂ ଵ

௧ భ ି௧ మ ெ ೅ǡబ

௄ భ 

### ݁ ି௄ భ ௧ భ 

### ቃ

20) Define t 1 

### = 0, then:

a. ܯ ෩ ் 

### ൌ ቂ ଵ

ି௧ మ ெ ೅ǡబ

௄ భ 

### ݁ ି௄ భ ௧ మ 

### ቃെቂ ଵ

ି௧ మ ெ ೅ǡబ

௄ భ 

### ቃ

b. ܯ ் 

### ൌ ቂ ெ ೅ǡబ

௄ భ ௧ మ 

### ቃ ሺ ͳെ݁ ି௄ భ ௧ మ 

### ሻ

21) Finally, defining t 2 

### =1, we have:

a. ܯ ෩ ் 

### ൌ ெ ೅ǡబ

௄ భ 

### ሺ ͳെ݁ ି௄ భ 

### ሻ

22) The total mass lost from the PEZ during one time step is calculated similarly:

a. ܯ ்ǡ଴ 

### െ ܯ ்ǡଵ 

### ൌ ܯ ்ǡ଴ 

### െ ܯ ்ǡ଴ 

### ݁ ି௄ భ 

### ൌ ܯ ்ǡ଴ 

### ሺ ͳെ݁ ି௄ భ 

### ሻ

23) The plant exposure EEC in units on each day is then:

a. ܥܧܧ ௜ 

### ൌ ெெ ೅

஺ ುಶೋ



### Once daily EECs are calculated, the peak EEC in each year simulated is identified. The values are sorted from greatest to least and value at the 90 percentile, the 1-10 year return frequency, is selected for the point estimate of exposure.

### Page 298 of 318 Appendix H. Spray drift regression curves using IORE.

The first order decay model is :
1) ௗ஼

ௗ௧ 

### ൌ െ݇ܥ

in differential form, and (2 ܥൌܥ ଴ 

### ݁ ௧௞ି



### in integrated form, where C is the concentration, k is rate constant with units of reciprocal time,

and C O 

### is initial concentration when t = 0. This equation commonly describes the degradation of chemicals when the rate is proportional to the concentration of the compound degrading. Empirically it is also useful to describe any process which rate of decrease is proportional to the concentration. Spray drift deposition roughly but not exactly follows this type of decrease with distance from the edge of field, i.e. (3 ܥൌܥ ଴ 

### ݁ ௟௞ି



### In this case, the concentration is the areal concentration in kg·ha -1 

### and l is the distance from the edge of the field and k is in units of reciprocal distance, l -1 

### , rather than reciprocal time. A related model with somewhat more flexibility which thus fits better to many data sets which are not exactly first-order in behavior is the indeterminate order model.
4) ௗ஼

ௗ௟ 

### ൌ െ݇ܥ ௡



### Where the order of the model n, is a variable parameter, and can be used to adjust the curvature of the line to more precisely fit decline curves. This is the same equation as IORE (Indeterminate Order Rate Equation) currently used by EFED for estimating degradation rate kinetics for soil and aquatic metabolism studies. To integrate this differential equation, it first must rearranged to separate the variables across the equal sign:
5) ௗ஼

஼ ೙ 

### ൌ െ݈݇݀

(6 ׬ ஼ௗ

஼ ೙ 

### ൌ െ݇ ׬ ݈݀

7) ஼ భష೙

ଵି௡ 

### ൌ ܭ െ ݈݇

Where K is constant of integration. When l = 0:

8) ஼ బ భష೙

ଵି௡ 

### ൌܭെ݇ൈͲ

9) ஼ బ భష೙

ଵି௡ 

### ܭ ൌ

Where C 0 

### is the concentration at l = 0. Substituting this into equation 7, we get:

10) ஼ భష೙

ଵି௡ 

### ൌ  ஼ బ భష೙

ଵି௡ 

### െ ݈݇

We can solve this explicitly for C to get integrated form of the indeterminate order rate equation

for decrease with distance. (11 ܥ ௡ ିଵ 

### ܥൌ ଴ ଵି௡ 

### െ ሺͳ െ ݊ሻ݈݇ 12) ሺ ͳെ݊ ሻ ሺܥሻ ൌ  ሺ ܥ ଴ ଵି௡ 

### െ ሺͳ െ ݊ሻ݈݇ ሻ

13) ሺܥሻ ൌ  ୪୬൫஼ బ భష೙ ିሺଵି௡ሻ௞௟൯

ሺ ଵି௡ ሻ

### Page 299 of 318 (14 ൌ ܥ ሾ ܥ ଴ ଵି௡ 

### െ ݈݇ሺͳ െ ݊ሻ ሿ భ ሺ భష೙ ሻ 

### This can be fit to deposition-versus-distance spray drift curves using, C 0 

### , k, and n as fitted parameters. It is also sometimes useful to know the distance from the edge of the field at which a certain concentration occurs; we can solve equation 11 for l to get:

15) ݈ ൌ ஼ బ భష೙ ି஼ భష೙

௞ ሺ ଵି௡ ሻ 

### To calculate the mean spray drift deposition across a buffer, you need to integrate the deposition across the buffer width and divide by the width:

(16 ܥ ҧ
ൌ ׬ ஼ൣ బ భష೙ ି௞௟ሺଵି௡ሻ൧ భ ሺ భష೙ ሻ ௗ௟ ೗ ೑

೗ బ
௟ ೑ ି௟ బ 

### We can make this problem simpler by making some substitutions: 17) ݖ ൌ ͳ െ ݊ǡݑ ൌ  ܥ ଴ ଵି௡ 

### െ ݈݇ݖ We can also differentiate u as function of l to get:
18) ௗ௨

ௗ௟ 

### ൌ  െ݇ݖ

We can then solve for dl to get:
19) ݈݀ ൌ  െ ௗ௨

௞௭ 

### Substituting equations 17 and 19 into 16 we get:

20) ܥ ҧ
ൌ ቀ షభ

ೖ೥ ቁ ׬ ௨ భ

೥ ௗ௨ ೠ ೑

ೠ బ
௟ ೑ ି௟ బ 

### Solving the integral expression we get:

(21 ܥ ҧ
ൌ ቀଵା భ

೥ ቁቀ షభ

ೖ೥ ቁቈ௨
೑ ቀ భశ భ

೥ ቁ

ି௨ బ ቀ భశ భ

೥ ቁ ቉

௟ ೑ ି௟ బ 

### We can the back substitute expressions for u f 

### and u 0 

### :

(22 ܥ ҧ
ൌ ቀଵା భ

೥ ቁቀ షభ

ೖ೥ ቁቈ஼

బ భష೙ ି௞௟ ೑ ௭ ቀ భశ భ

೥ ቁ ି஼ బ భష೙ ା௞௟ బ ௭ ቀ భశ భ

೥ ቁ ቉

௟ ೑ ି௟ బ 

### This can be rearranged and simplified to

ܥ ҧ
ൌ ቀ ͳ൅ݖ
݇ݖ ଶ 

### ቁ ቈ ݇ݖ݈ ଴ ቀଵା ଵ

௭ ቁ 

### െ ൫݇ݖ݈ ௙ 

### ൯ ቀଵା ଵ

௭ ቁ 

### ቉

݈ ଴ 

### െ ݈ ௙

### Page 300 of 318 The linear equilibrium partition equation for partitioning a chemical between a mass of soil and a

volume of water is:

A1)  ୢ 

### ൌ େ ౩౥౟ౢ

େ ౗౧ 

### ൌ ౣ ౩౥౟ౢ

౉ ౩౥౟ౢ

ౣ ౗౧

౒ 

### Where K d 

### is the soil-water partition coefficient, C soil 

### is the concentration of the chemical on soil,

C aq 

### is the concentration of the chemical in water, m soil 

### is the mass of the pesticide on the soil, m aq 

### is the mass of the pesticide in solution, M soil 

### is the mass of the soil, and V is the volume of water.

K d 

### , M soil 

### , and V are known constant values, whereas, m soil 

### and m aq 

### can vary. However, in the case where the total mass of pesticide m T 

### is known: A2) ݉ ் 

### ൌ ݉ ௦௢௜௟ 

### ൅ ݉ ௔௤ 

### that is, the total mass is equal to the mass on soil plus the mass in solution. If we solve equation 2 for m soil 

### and substitute into equation A1:

A3)  ୢ 

### ൌ େ ౩౥౟ౢ

େ ౗౧ 

### ൌ ౣ ౐ షౣ ౗౧

౉ ౩౥౟ౢ

ౣ ౗౧

౒ 

### We can then rearrange, and solve for m aq 

### ,  ୢ 

###  ୟ୯ 

###  ൌ  ୘ 

### െ  ୟ୯ 

###  ୱ୭୧୪ 

###  ୢ 

###  ୟ୯ 

###  ൌ  ୘


###  ୱ୭୧୪ 

### െ  ୟ୯ 

###  ୱ୭୧୪ 

###  ୢ 

###  ୟ୯ 

###  ൅  ୟ୯ 

###  ୱ୭୧୪ 

### ൌ  ୘


###  ୱ୭୧୪ 

###  ୢ 

###  ୱ୭୧୪ 

###  ୟ୯ 

###  ୱ୭୧୪ 

### ൅  ୟ୯ 

###  ୱ୭୧୪ 

### ൌ  ୘


###  ୱ୭୧୪ 

### ሺ  ୢ 

###  ୱ୭୧୪ 

### ൅  ሻ  ୟ୯ 

###  ୱ୭୧୪ 

### ൌ  ୘


###  ୱ୭୧୪ 

### A4)  ୟ୯ 

### ൌ ୫ ౐ ୚
ሺ ୏ ౚ ୑ ౩౥౟ౢ ା୚ ሻ



### m aq

### Page 301 of 318 Appendix I. Maximum Single Application Rates for Labeled Uses of SU Herbicides.

Crop Chemical Maximum Single Application Rate Method

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Chlorsulfuron 0.062 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Halosulfuron 0.14 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Metsulfuron 0.0375 ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Sulfometuron 0.375 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Sulfosulfuron 0.094 ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE thifensulfuron 0.028 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Triasulfuron 0.028 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE Tribenuron 0.0156 Ground or air

AGRICULTURAL FALLOW/IDLELAND /

CONSERVATION RESERVE trifloxysulfuron 0.007 ground
Agricultural farm premisis Sulfometuron 0.25 ground

AGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Chlorsulfuron 0.125 Ground or air

AGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Metsulfuron 0.15 ground or air

AGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Nicosulfuron 0.07 ground or air

AGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Rimsulfuron 0.0625 Ground or air

AGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Sulfometuron 0.375 ground or air

AGRICULTURAL UNCULTIVATED AREAS Chlorsulfuron 0.125 Ground or air

AGRICULTURAL UNCULTIVATED AREAS Metsulfuron 0.15 ground or air

AGRICULTURAL UNCULTIVATED AREAS Nicosulfuron 0.07 ground or air

AGRICULTURAL UNCULTIVATED AREAS Rimsulfuron 0.0625 Ground or air
Agricultural uncultivated areas Sulfometuron 0.375 ground or air AGRICULTURAL/FARM PREMISES Chlorsulfuron 0.125 Ground or air AGRICULTURAL/FARM PREMISES Metsulfuron 0.15 ground or air AGRICULTURAL/FARM PREMISES Rimsulfuron 0.0625 Ground or air AIRPORTS/LANDING FIELDS Chlorsulfuron 0.14 ground AIRPORTS/LANDING FIELDS Halosulfuron 0.068 Ground AIRPORTS/LANDING FIELDS Metsulfuron 0.15 ground or air

### Page 302 of 318 Crop Chemical Maximum Single Application Rate Method

AIRPORTS/LANDING FIELDS Nicosulfuron 0.053 ground or air AIRPORTS/LANDING FIELDS Rimsulfuron 0.0625 Ground or air AIRPORTS/LANDING FIELDS Sulfometuron 0.375 ground or air AIRPORTS/LANDING FIELDS Sulfosulfuron 0.094 ground or air AIRPORTS/LANDING FIELDS trifloxysulfuron 0.036 ground

ALFALFA Halosulfuron 0.047 Ground

ALFALFA Tribenuron 0.014 Ground or air

ALMOND Halosulfuron 0.063 Ground

ALMOND trifloxysulfuron 0.1875 ground

Almonds Rimsulfuron 0.0625 various

APPLE Halosulfuron 0.094 Ground
Apples Rimsulfuron 0.0625 various ground
Apricots Rimsulfuron 0.0625 various ground

ARRACACIA (PERSIAN CARROT) Halosulfuron 0.047 Ground

ARROWROOT Halosulfuron 0.047 Ground

ARTICHOKE, CHINESE Halosulfuron 0.047 Ground

ARTICHOKE, JERUSALEM Halosulfuron 0.047 Ground

ASPARAGUS Halosulfuron 0.0703 Ground

BARLEY Chlorsulfuron 0.0156 Ground or air

BARLEY Metsulfuron 0.0078 ground or air Barley Prosulfuron 0.018 Ground or air

BARLEY thifensulfuron 0.028 Ground or air

BARLEY Triasulfuron 0.026 Ground or air

BARLEY Tribenuron 0.0156 Ground or air

BEANS Ͳ DRIED

Ͳ TYPE Tribenuron 0.014 Ground or air

BEANS Ͳ SUCCULENT (SNAP) Tribenuron 0.014 Ground or air

BEANS, DRIED

Ͳ TYPE Halosulfuron 0.047 Ground

BEANS, SUCCULENT (LIMA) Halosulfuron 0.047 Ground

BEANS, SUCCULENT (SNAP) Halosulfuron 0.047 Ground

BEECH NUT Halosulfuron 0.062 Ground

Beech Nut Rimsulfuron 0.0625 various ground

Beets Triflusulfuron 0.016 Ground or air

BERMUDAGRASS Metsulfuron 0.024 ground or air

BERMUDAGRASS Nicosulfuron 0.066 ground or air

BERMUDAGRASS Sulfosulfuron 0.094 ground

Black spruce Sulfometuron 0.1875 Ground or air

BLACK SPRUCE (FOREST) Metsulfuron 0.05 ground or air

Blue spruce Sulfometuron 0.04875 ground

BLUEBERRY Tribenuron 0.0313 Ground or air

Bluegrass primisulfuron 0.036 ground or air

### Page 303 of 318 Crop Chemical Maximum Single Application Rate Method

BRAZIL NUT Halosulfuron 0.062 Ground

Brazil Nut Rimsulfuron 0.0625 various ground

BUSHBERRIES Halosulfuron 0.047 Ground

Butter nut Rimsulfuron 0.0625 various ground

BUTTERNUT Halosulfuron 0.062 Ground

CABBAGE Tribenuron 0.014 Ground or air

Calamondin Rimsulfuron 0.0625 various ground Canola/Rapse seed Ethametsulfuron 0.019 ground
CANOLA\RAPE thifensulfuron 0.028 Ground or air CANOLA\RAPE Tribenuron 0.0156 Ground or air

CARROT (INCLUDING TOPS) Tribenuron 0.014 Ground or air

CASHEW Halosulfuron 0.062 Ground

Cashew Rimsulfuron 0.0625 various ground

CEREAL GRAINS Tribenuron 0.014 Ground or air

CHAYOTE Halosulfuron 0.047 Ground

Cherry Rimsulfuron 0.0625 various ground

CHESTNUT Halosulfuron 0.062 Ground

Chestnut Rimsulfuron 0.0625 various ground
Chicory Triflusulfuron 0.016 Ground or air

CHINQUAPIN Halosulfuron 0.062 Ground

Chinquapin Rimsulfuron 0.0625 various ground

CHRISTMAS TREE PLANTATIONS Sulfometuron 0.0975 Ground or air

CHUFA (GROUND ALMOND) Halosulfuron 0.047 Ground

Citron Rimsulfuron 0.0625 various ground

CITRUS trifloxysulfuron 0.1875 ground

Citrus hybrids Rimsulfuron 0.0625 various ground

CLOVER Tribenuron 0.014 Ground or air

Commercial lawns Rimsulfuron 0.031 Ground

Commercial premises and equipment Rimsulfuron 0.063 Ground

COMMERCIAL STORAGES/WAREHOUSES

PREMISES Chlorsulfuron 0.141 ground

COMMERCIAL STORAGES/WAREHOUSES

PREMISES Metsulfuron 0.075 ground or air

COMMERCIAL STORAGES/WAREHOUSES

PREMISES Sulfosulfuron 0.094 ground or air COMMERCIAL/INDUSTRIAL LAWNS Chlorsulfuron 0.141 Ground or air Commercial/Industrial lawns Flazasulfuron 0.093 ground Commercial/Industrial lawns Foramsulfuron 0.052 ground COMMERCIAL/INDUSTRIAL LAWNS Halosulfuron 0.068 Ground Commercial/Industrial lawns iodosulfuron 0.0089 ground

### Page 304 of 318 Crop Chemical Maximum Single Application Rate Method

COMMERCIAL/INDUSTRIAL LAWNS Metsulfuron 0.087 ground or air COMMERCIAL/INDUSTRIAL LAWNS Sulfometuron 0.1875 Ground or air COMMERCIAL/INDUSTRIAL LAWNS Sulfosulfuron 0.094 ground COMMERCIAL/INDUSTRIAL LAWNS trifloxysulfuron 0.036 ground COMMERCIAL/INSTITUTIONAL/INDUSTRIAL PREMISES/EQUIPMENT (OUTDOOR) Halosulfuron 0.068 Ground COMMERCIAL/INSTITUTIONAL/INDUSTRIAL PREMISES/EQUIPMENT (OUTDOOR) Metsulfuron 0.15 ground or air COMMERCIAL/INSTITUTIONAL/INDUSTRIAL PREMISES/EQUIPMENT (OUTDOOR) Sulfosulfuron 0.094 ground

CONIFER RELEASE Metsulfuron 0.15 ground or air

CONIFER RELEASE Sulfosulfuron 0.094 ground or air

Corn Chlorimuron 0.063 Ground or air

Corn Foramsulfuron 0.038 Ground or air

Corn Halosulfuron 0.09375 Ground or air

Corn Iodosulfuron 0.0019 ground

corn primisulfuron 0.036 Ground or air

Corn Prosulfuron 0.036 Ground or air

Corn Rimsulfuron 0.0625 Ground or air

Corn thifensulfuron 0.028 Ground or air

Corn Tribenuron 0.0156 Ground or air

CORN (SILAGE) Halosulfuron 0.031 Ground or air

CORN (SILAGE) Tribenuron 0.014 Ground or air

CORN, FIELD Halosulfuron 0.09375 Ground or air

CORN, FIELD Nicosulfuron 0.066 ground or air

CORN, FIELD thifensulfuron 0.028 Ground or air

CORN, FIELD Tribenuron 0.0313 Ground or air

CORN, POP Halosulfuron 0.047 Ground or air

CORN, POP Nicosulfuron 0.066 ground or air

CORN, POP Tribenuron 0.014 Ground or air

CORN, SWEET Halosulfuron 0.047 Ground or air

CORN, SWEET Nicosulfuron 0.066 ground or air

CORN, SWEET Tribenuron 0.014 Ground or air

COTTON (UNSPECIFIED) Halosulfuron 0.062 Ground

COTTON (UNSPECIFIED) Iodosulfuron 0.0019 ground

COTTON (UNSPECIFIED) rimsulfuron 0.016 Ground or air

COTTON (UNSPECIFIED) thifensulfuron 0.025 Ground or air

COTTON (UNSPECIFIED) Tribenuron 0.0156 Ground or air

COTTON (UNSPECIFIED) trifloxysulfuron 0.036 ground
Crabapple Rimsulfuron 0.0625 various ground

### Page 305 of 318 Crop Chemical Maximum Single Application Rate Method

Crambe Ethametsulfuron 0.019 ground
cropland rimsulfuron 0.031 sprayer

CUCUMBER Halosulfuron 0.047 Ground

CUCUMBER Tribenuron 0.014 Ground or air

CUCURBIT VEGETABLES Halosulfuron 0.047 Ground

DOUGLAS

Ͳ FIR (FOREST/SHELTERBELT) Metsulfuron 0.077 ground or air

DOUGLAS

Ͳ FIR (FOREST/SHELTERBELT) Sulfometuron 0.1998 Ground or air

DRAINAGE SYSTEMS Metsulfuron 0.15 ground or air

drainage systems Rimsulfuron 0.0625 Ground or air

DRAINAGE SYSTEMS Sulfometuron 0.375 Ground or air

DRAINAGE SYSTEMS Sulfosulfuron 0.094 ground or air

EASTERN WHITE PINE (FOREST) Sulfometuron 0.0703 Ground or air

EGGPLANT Halosulfuron 0.047 Ground

Endive Triflusulfuron 0.016 Ground or air

Filbert Rimsulfuron 0.0625 various ground

FILBERT (HAZELNUT) Halosulfuron 0.062 Ground

FIR (FOREST/SHELTERBELT) Sulfometuron 0.0975 Ground or air

FLAX thifensulfuron 0.0094 Ground or air

FLAX Tribenuron 0.014 Ground or air

FOREST PLANTINGS (REFORESTATION PROGRAMS)(TREE FARMS, TREE
PLANTATIONS, ETC.) Sulfometuron 0.23 ground

FOREST TREE MANAGEMENT/FOREST PEST

MANAGEMENT Metsulfuron 0.15 ground or air

FOREST TREE MANAGEMENT/FOREST PEST

MANAGEMENT Sulfometuron 0.198 Ground or air

FOREST TREES (ALL OR UNSPECIFIED) Sulfometuron 0.28 Ground or air

FOREST TREES (ALL OR UNSPECIFIED) Sulfosulfuron 0.0623 ground

FOREST TREES (HARDWOODS, BROADLEAF TREES) Metsulfuron 0.075 ground or air

FOREST TREES (HARDWOODS, BROADLEAF TREES) Sulfometuron 0.23 Ground or air

FOREST TREES (HARDWOODS, BROADLEAF TREES) Sulfosulfuron 0.0623 ground

FRASER FIR (FOREST/SHELTERBELT) Sulfometuron 0.0975 Ground or air

FRUITING VEGETABLES Halosulfuron 0.047 Ground

GINGER Halosulfuron 0.047 Ground

Golf course turf Flazasulfuron 0.093 ground

Golf course turf Foramsulfuron 0.052 ground

GOLF COURSE TURF Halosulfuron 0.068 Ground

Golf course turf iodosulfuron 0.0089 ground

### Page 306 of 318 Crop Chemical Maximum Single Application Rate Method

GOLF COURSE TURF Metsulfuron 0.0375 ground or air

Golf course turf Rimsulfuron 0.031 sprayer

GOLF COURSE TURF Sulfosulfuron 0.094 ground

GOLF COURSE TURF trifloxysulfuron 0.036 ground

GOURDS Halosulfuron 0.047 Ground

Grains, cereal iodosulfuron 0.0019 ground

Grains, small Prosulfuron 0.018 Ground or air

GRAND FIR (FOREST) Metsulfuron 0.075 ground or air

GRAND FIR (FOREST) Sulfometuron 0.1875 Ground or air Grapefruit Rimsulfuron 0.0625 various ground

grapes Rimsulfuron 0.0625 various ground

Grapes (added for flazasulfuron because of

BEAD input) Flazasulfuron 0.045  GRASS FORAGE/FODDER/HAY Metsulfuron 0.0094 ground or air

GRASS FORAGE/FODDER/HAY Nicosulfuron 0.035 ground or air

GRASS FORAGE/FODDER/HAY Sulfosulfuron 0.094 ground or air

GRASSES GROWN FOR SEED Chlorsulfuron 0.0117 Ground or air

GRASSES GROWN FOR SEED Halosulfuron 0.065 Ground

HEMLOCK (FOREST/SHELTERBELT) Sulfometuron 0.1875 Ground or air

HICKORY NUT Halosulfuron 0.062 Ground

Hickory nut Rimsulfuron 0.0625 various ground HOUSEHOLD/DOMESTIC DWELLINGS

OUTDOOR PREMISES Halosulfuron 0.068 Ground HOUSEHOLD/DOMESTIC DWELLINGS

OUTDOOR PREMISES Sulfosulfuron 0.094 ground

HYBRID COTTONWOOD/POPLAR

PLANTATIONS Sulfometuron 0.105 Ground or air

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Chlorsulfuron 0.14 ground

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Halosulfuron 0.136 Ground

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Metsulfuron 0.15 ground or air

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Nicosulfuron 0.07 ground or air

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Sulfometuron 0.375 Ground or air

INDUSTRIAL / CONSTRUCTION AREAS (OUTDOOR) Sulfosulfuron 0.094 ground or air Industrial/construction areas Rimsulfuron 0.0625 Ground or air

INTERMITTENTLY FLOODED AREAS/WATER Chlorsulfuron 0.14 ground

### Page 307 of 318 Crop Chemical Maximum Single Application Rate Method

INTERMITTENTLY FLOODED AREAS/WATER Metsulfuron 0.15 ground or air

INTERMITTENTLY FLOODED AREAS/WATER Nicosulfuron 0.07 ground or air

INTERMITTENTLY FLOODED AREAS/WATER Sulfometuron 0.375 Ground or air

JACK PINE (FOREST) Sulfometuron 0.375 Ground or air
Kumquat Rimsulfuron 0.0625 various ground

Lemon Rimsulfuron 0.0625 various ground

LENTILS Tribenuron 0.014 Ground or air

LEREN Halosulfuron 0.047 Ground

Lime Rimsulfuron 0.0625 various ground

LOBLOLLY PINE (FOREST) Metsulfuron 0.15 ground or air

LOBLOLLY PINE (FOREST) Sulfometuron 0.375 Ground or air

LODGEPOLE PINE (FOREST/SHELTERBELT) Sulfometuron 0.1875 Ground or air

LONGLEAF PINE (FOREST) Metsulfuron 0.038 ground or air

LONGLEAF PINE (FOREST) Sulfometuron 0.375 Ground or air
Loquat Rimsulfuron 0.0625 various ground

Macadamia nut Rimsulfuron 0.0625 various ground

MACADAMIA NUT (BUSHNUT) Halosulfuron 0.062 Ground

MANIOC (CASSAVA) Halosulfuron 0.047 Ground
Mayhaw Rimsulfuron 0.0625 various ground

MELONS Ͳ WATER Tribenuron 0.014 Ground or air

MELONS, CANTALOUPE Halosulfuron 0.047 Ground

MELONS, HONEYDEW Halosulfuron 0.047 Ground

MELONS, WATER Halosulfuron 0.047 Ground

MELONS, WINTER (CASABA/CRENSHAW/HONEYDEW/PERSIAN) Halosulfuron 0.047 Ground

Millit Prosulfuron 0.018 Ground or air

MUSTARD Tribenuron 0.014 Ground or air

Nectarine Rimsulfuron 0.0625 various ground

NOBLE FIR (FOREST) Sulfometuron 0.13 Ground or air

non

Ͳ Ag rights of ways Rimsulfuron 0.0625 Ground or air
Nonag Uncultivated areas/soils Rimsulfuron 0.0625 Ground or air

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Chlorsulfuron 0.14 Ground or air

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Halosulfuron 0.136 Ground

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Metsulfuron 0.15 ground or air

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Nicosulfuron 0.07 ground or air

### Page 308 of 318 Crop Chemical Maximum Single Application Rate Method

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Sulfometuron 0.375 Ground or air

NONAGRICULTURAL RIGHTS

Ͳ OF

Ͳ WAY/FENCEROWS/HEDGEROWS Sulfosulfuron 0.094 ground or air

NONAGRICULTURAL UNCULTIVATED AREAS/SOILS Chlorsulfuron 0.14 ground

NONAGRICULTURAL UNCULTIVATED AREAS/SOILS Halosulfuron 0.136 Ground

NONAGRICULTURAL UNCULTIVATED AREAS/SOILS Metsulfuron 0.15 ground or air

NONAGRICULTURAL UNCULTIVATED AREAS/SOILS Sulfometuron 0.375 Ground or air

NONAGRICULTURAL UNCULTIVATED AREAS/SOILS Sulfosulfuron 0.094 ground or air

OATS Chlorsulfuron 0.023 Ground or air

Oats Prosulfuron 0.018 Ground or air

OATS thifensulfuron 0.028 Ground or air

OATS Tribenuron 0.0156 Ground or air

OKRA Halosulfuron 0.047 Ground

ONION Tribenuron 0.014 Ground or air
Orange Rimsulfuron 0.0625 various ground

ORNAMENTAL AND/OR SHADE TREES Halosulfuron 0.068 Ground

ORNAMENTAL AND/OR SHADE TREES Sulfosulfuron 0.094 ground

ORNAMENTAL GRASSES Metsulfuron 0.00375 ground or air

ORNAMENTAL GRASSES Sulfosulfuron 0.094 ground

ORNAMENTAL GROUND COVER Halosulfuron 0.065 Ground

ORNAMENTAL GROUND COVER Sulfosulfuron 0.059 ground

ORNAMENTAL HERBACEOUS PLANTS Halosulfuron 0.065 Ground

ORNAMENTAL HERBACEOUS PLANTS Sulfosulfuron 0.094 ground

Ornamental Lawns (Cool Season) Sulfosulfuron 0.035 ground

Ornamental Lawns (Warm Season) Sulfosulfuron 0.094 ground

ORNAMENTAL LAWNS AND TURF Chlorsulfuron 0.122 ground

Ornamental lawns and turf Flazasulfuron 0.093 ground

Ornamental lawns and turf Foramsulfuron 0.052 ground

Ornamental lawns and turf Foramsulfuron 0.052 ground

ORNAMENTAL LAWNS AND TURF Halosulfuron 0.068 Ground

Ornamental lawns and turf iodosulfuron 0.0089 ground

ORNAMENTAL LAWNS AND TURF Metsulfuron 0.039 ground or air

ORNAMENTAL LAWNS AND TURF Sulfometuron 0.21 Ground or air

ORNAMENTAL LAWNS AND TURF Sulfosulfuron 0.063 ground

ORNAMENTAL NONFLOWERING PLANTS Halosulfuron 0.065 Ground

### Page 309 of 318 Crop Chemical Maximum Single Application Rate Method

ORNAMENTAL NONFLOWERING PLANTS Sulfosulfuron 0.094 ground

ORNAMENTAL SOD FARM (TURF) Chlorsulfuron 0.122 ground

ORNAMENTAL SOD FARM (TURF) Flazasulfuron 0.093 ground

ORNAMENTAL SOD FARM (TURF) Halosulfuron 0.065 Ground or air

ORNAMENTAL SOD FARM (TURF) iodosulfuron 0.0089 ground

ORNAMENTAL SOD FARM (TURF) Metsulfuron 0.0375 ground or air

ORNAMENTAL SOD FARM (TURF) Rimsulfuron 0.031 sprayer

ORNAMENTAL SOD FARM (TURF) Sulfosulfuron 0.094 ground

ORNAMENTAL SOD FARM (TURF) trifloxysulfuron 0.036 ground

ORNAMENTAL WOODY SHRUBS AND VINES Halosulfuron 0.065 Ground

ORNAMENTAL WOODY SHRUBS AND VINES Sulfosulfuron 0.059 ground

PASTURES Chlorsulfuron 0.062 Ground or air

PASTURES Metsulfuron 0.059 ground or air

PASTURES Sulfosulfuron 0.094 ground or air

PASTURES Triasulfuron 0.0275 Ground or air

PASTURES Tribenuron 0.014 Ground or air PATHS/PATIOS Metsulfuron 0.091 ground or air

Paved areas Rimsulfuron 0.0625 Ground or air

PAVED AREAS (PRIVATE ROADS/SIDEWALKS) Chlorsulfuron 0.125 ground

PAVED AREAS (PRIVATE ROADS/SIDEWALKS) Sulfometuron 0.25 ground

PAVED AREAS (PRIVATE ROADS/SIDEWALKS) Sulfosulfuron 0.094 ground or air

Peach Rimsulfuron 0.0625 various ground

Peanunts Chlorimuron 0.0078 Ground or air

PEANUTS (UNSPECIFIED) Tribenuron 0.014 Ground or air

Pear Rimsulfuron 0.0625 various ground

PEAS (UNSPECIFIED) Tribenuron 0.014 Ground or air

PEAS, SUCCULENT Halosulfuron 0.047 Ground

PECAN Halosulfuron 0.062 Ground

Pecan Rimsulfuron 0.0625 various ground

PEPPER Halosulfuron 0.047 Ground

PEPPER (CHILI TYPE) Halosulfuron 0.047 Ground

PISTACHIO Halosulfuron 0.062 Ground

Pistachio Rimsulfuron 0.0625 various ground

Plum Rimsulfuron 0.0625 various ground

PONDEROSA PINE (FOREST) Metsulfuron 0.075 ground or air

PONDEROSA PINE (FOREST) Sulfometuron 0.198 Ground or air

POPLAR (FOREST/SHELTERBELT) Metsulfuron 0.075 ground or air

Potato Rimsulfuron 0.023 Ground or air

POTATO, WHITE/IRISH Halosulfuron 0.047 Ground

POTATO, WHITE/IRISH Tribenuron 0.014 Ground or air

### Page 310 of 318 Crop Chemical Maximum Single Application Rate Method

Private roads Chlorimuron 0.0313 ground

Prune Rimsulfuron 0.0625 various ground

Pummelo Rimsulfuron 0.0625 various ground

PUMPKIN Halosulfuron 0.047 Ground

PUMPKIN Tribenuron 0.014 Ground or air

Quince Rimsulfuron 0.0625 various ground

RANGELAND Chlorsulfuron 0.062 Ground or air

RANGELAND Metsulfuron 0.059 ground or air

Rangeland Rimsulfuron 0.0625 Ground or air

RANGELAND Sulfometuron 0.0703 Ground or air

RANGELAND Sulfosulfuron 0.0623 ground or air

RANGELAND Triasulfuron 0.0275 Ground or air

Recreational area lawns Flazasulfuron 0.093 ground

Recreational area lawns Foramsulfuron 0.052 ground

Recreational area lawns iodosulfuron 0.0089 ground

Recreational area lawns Metsulfuron 0.0375 ground or air

Recreational area lawns Sulfosulfuron 0.094 ground

RECREATIONAL AREAS Halosulfuron 0.068 Ground

RECREATIONAL AREAS Metsulfuron 0.091 ground or air

Recreational Areas Rimsulfuron 0.031 sprayer

RECREATIONAL AREAS trifloxysulfuron 0.036 ground

RED PINE (FOREST/SHELTERBELT) Metsulfuron 0.075 ground or air

RED PINE (FOREST/SHELTERBELT) Sulfometuron 0.094 Ground or air

REDCEDAR (FOREST/SHELTERBELT) Metsulfuron 0.075 ground or air

REDCEDAR (FOREST/SHELTERBELT) Sulfometuron 0.14 Ground or air

REDWOOD (FOREST) Sulfometuron 0.1875 Ground or air REFUSE/SOLID WASTE SITES (OUTDOOR) Metsulfuron 0.075 ground or air REFUSE/SOLID WASTE SITES (OUTDOOR) Sulfometuron 0.28 Ground or air

RESIDENTIAL LAWNS Halosulfuron 0.068 Ground

Residential lawns iodosulfuron 0.0089 ground

RESIDENTIAL LAWNS Sulfosulfuron 0.094 ground

RESIDENTIAL LAWNS trifloxysulfuron 0.036 ground

RHUBARB Halosulfuron 0.047 Ground

Rice Bensulfuron 0.063 Ground or air

RICE Halosulfuron 0.062 Ground or air

Rice Orthosulfamuron 0.066 Ground or air

RICE thifensulfuron 0.028 Ground or air

RICE Tribenuron 0.0156 Ground or air
Rights of ways Chlorimuron 0.0313 ground

ROOT AND TUBER VEGETABLES Halosulfuron 0.047 Ground

### Page 311 of 318 Crop Chemical Maximum Single Application Rate Method

Rye Prosulfuron 0.018 Ground or air

SAFFLOWER (UNSPECIFIED) thifensulfuron 0.01875 Ground or air

SCOTCH PINE (FOREST/SHELTERBELT) Sulfometuron 0.049 Ground or air

SEWAGE DISPOSAL AREAS Chlorsulfuron 0.14 ground

SEWAGE DISPOSAL AREAS Metsulfuron 0.15 ground or air

SEWAGE DISPOSAL AREAS Nicosulfuron 0.07 ground or air

SEWAGE DISPOSAL AREAS Sulfometuron 0.375 Ground or air

SHORTLEAF PINE (FOREST) Sulfometuron 0.094 Ground or air

SITKA SPRUCE (FOREST) Metsulfuron 0.075 ground or air

SITKA SPRUCE (FOREST) Sulfometuron 0.19 Ground or air

SLASH PINE (FOREST) Metsulfuron 0.15 ground or air

SLASH PINE (FOREST) Sulfometuron 0.375 Ground or air

SORGHUM Halosulfuron 0.032 Ground or air

sorghum Iodosulfuron 0.0019 ground
sorghum Prosulfuron 0.036 Ground or air Sorghum Rimsulfuron 0.016 Ground or air

SORGHUM thifensulfuron 0.028 Ground or air

SORGHUM Tribenuron 0.0156 Ground or air

SORGHUM (UNSPECIFIED) Nicosulfuron 0.047 ground or air

SORGHUM (UNSPECIFIED) Tribenuron 0.014 Ground or air Soybeans Chlorimuron 0.08 Ground or air
Soybeans Iodosulfuron 0.0019 ground
Soybeans Rimsulfuron 0.0625 Ground or air

SOYBEANS (UNSPECIFIED) Halosulfuron 0.062 Ground or air

SOYBEANS (UNSPECIFIED) thifensulfuron 0.028 Ground or air

SOYBEANS (UNSPECIFIED) Tribenuron 0.0313 Ground or air

SQUASH (ALL OR UNSPECIFIED) Halosulfuron 0.047 Ground

SQUASH (SUMMER) Halosulfuron 0.047 Ground

SQUASH (WINTER) (HUBBARD) Halosulfuron 0.047 Ground

SUGAR BEET thifensulfuron 0.028 Ground or air

SUGAR BEET Tribenuron 0.0156 Ground or air

Sugar beet Triflusulfuron 0.031 Ground or air

SUGARCANE Halosulfuron 0.062 Ground or air

SUGARCANE Metsulfuron 0.125 ground or air

SUGARCANE trifloxysulfuron 0.028 ground

SUNFLOWER Tribenuron 0.0156 Ground or air SWAMPS/MARSHES/WETLANDS/STAGNANT

WATER Chlorsulfuron 0.14 ground SWAMPS/MARSHES/WETLANDS/STAGNANT

WATER Metsulfuron 0.15 ground or air

### Page 312 of 318 Crop Chemical Maximum Single Application Rate Method

SWAMPS/MARSHES/WETLANDS/STAGNANT

WATER Nicosulfuron 0.07 ground or air SWAMPS/MARSHES/WETLANDS/STAGNANT

WATER Sulfometuron 0.375 Ground or air
Sweage disposal areas Rimsulfuron 0.0625 Ground or air

SWEET POTATO Halosulfuron 0.047 Ground

SWEET POTATO Tribenuron 0.014 Ground or air
Tangelo Rimsulfuron 0.0625 various ground
Tangerines Rimsulfuron 0.0625 various ground

TARO Halosulfuron 0.047 Ground

TOBACCO Tribenuron 0.014 Ground or air

TOMATO Halosulfuron 0.047 Ground

Tomato Rimsulfuron 0.0625 various ground

TOMATO Tribenuron 0.014 Ground or air

TOMATO trifloxysulfuron 0.0094 ground

TRITICALE Chlorsulfuron 0.016 Ground or air

Triticale Iodosulfuron 0.0026 ground

Triticale mesosulfuron 0.013 Ground or air

TRITICALE Metsulfuron 0.00375 ground or air

Triticale Prosulfuron 0.018 Ground or air

TRITICALE thifensulfuron 0.028 Ground or air

TRITICALE Tribenuron 0.0156 Ground or air

TURMERIC Halosulfuron 0.047 Ground

uncultivated Chlorimuron 0.0313 ground

UTILITY POLES / RIGHT

Ͳ OF

Ͳ WAY Chlorsulfuron 0.122 ground

UTILITY POLES / RIGHT

Ͳ OF

Ͳ WAY Metsulfuron 0.15 ground or air

UTILITY POLES / RIGHT

Ͳ OF

Ͳ WAY Nicosulfuron 0.07 ground or air

UTILITY POLES / RIGHT

Ͳ OF

Ͳ WAY Sulfometuron 0.375 Ground or air

UTILITY POLES / RIGHT

Ͳ OF

Ͳ WAY Sulfosulfuron 0.094 ground or air

VIRGINIA PINE (FOREST) Sulfometuron 0.375 Ground or air

Walnut Rimsulfuron 0.0625 various ground

WALNUT (ENGLISH/BLACK) Halosulfuron 0.062 Ground

WESTERN HEMLOCK (FOREST) Metsulfuron 0.075 ground or air

WESTERN HEMLOCK (FOREST) Sulfometuron 0.198 Ground or air

WESTERN LARCH (FOREST) Sulfometuron 0.19 Ground or air

WHEAT Chlorsulfuron 0.023 Ground or air

Wheat Iodosulfuron 0.0089 ground

Wheat mesosulfuron 0.013 Ground or air

WHEAT Metsulfuron 0.0078 ground or air

Wheat Prosulfuron 0.018 Ground or air

### Page 313 of 318 Crop Chemical Maximum Single Application Rate Method

WHEAT Sulfosulfuron 0.0316 ground or air

WHEAT thifensulfuron 0.028 Ground or air

WHEAT Triasulfuron 0.026 Ground or air

WHEAT Tribenuron 0.0156 Ground or air

WHITE FIR (FOREST/SHELTERBELT) Sulfometuron 0.19 Ground or air

WHITE PINES (FOREST) Sulfometuron 0.19 Ground or air

WHITE SPRUCE (FOREST/SHELTERBELT) Sulfometuron 0.14 Ground or air

YAM Halosulfuron 0.047 Ground

YAM Tribenuron 0.014 Ground or air

YAM BEAN Halosulfuron 0.047 Ground

YAUTIA Halosulfuron 0.047 Ground

### Page 314 of 318 Appendix J. Analysis of Non-Plant Toxicity DataFreshwater organisms Estuarine/marine organismsAcutetebrate EC50(ppm)ChronicInvertebrateNOAEC (ppm)(endpointaffected)Acute FishLC50(ppm)Chronic FishNOAEC (ppm)(endpoint affected)AcuteInvertebrate EC50(ppm)ChronicInvertebrateNOAEC (ppm)(endpointaffected)Acute Fish LC50(ppm)Chronic FishNOAEC(ppm)Endpointaffectedhnia magna Daphnia magnaBluegill orRainbow troutRainbow trout orFathead minnowEastern oyster ormysidMysidSheepsheadminnowSheepsheadminnow>7117(growth andreproduction)>631.5(not indicated)>130 NA>123 NA>100.106(growth)>108.2(not indicated)NA NANA NA>37020(reproduction)>30032(growth)>89 NA>980 NA>1066.39(survival andyoung/adult)115.217(larval survival)107 NA>140 NA>102.5100(none)>10010.5(none)118 NA>93.6 NA>1070.98(not indicated)>11834(none)94 NA>125 NANA NA>86.99.1(decrease #young per femaleand dry weight)>88.110.2(none)>100 NA>100 NA>90.21.7(dry weight)>91.5>29.6(not indicated)>111 NA>105 NA>150 NA >1504.5(weight)NA NANA NA>100043(not indicated)>1000 NA NA NANA NA>97.36.5(growth)>1226.1(growth)>9727(not indicated)>123 NAPage316of318Primisulfuronmethyl>1000.41(not indicated)21011(none)16 NA>100 NAProsulfuron >120140(Growth,survival andreproduction)>155149(growth, survivaland hatchling)>150 NA>155 NARimsulfuron >390 NA >390 NA >110 NA >110 NASulfometuronmethyl>15097(not listed)>148 NA >38.2 NA>45 NASulfosulfuron >94.6102(none)>93.6100(none)>106 NA>101 NAThifensulfuronmethyl>100 NA >100 NA NA NANA NATriasulfuron>100105(not indicated)>10068.6(not indicated)21.5 NA>100 NATribenuronmethyl720114(none)>10011.8(none)>1351.51(survival)>132 NATrifloxysulfuronNa>1080.549(# of offspringand reproductiveday)>1039.52(none)60.1 NA>103 NATriflusulfuronmethylNA NA NA NA NA NA NA NAPage317of318Avian MammalianTerrestrialInvertebratesAcute Oral LD50(ppm)Acute Dietary LC50(ppm)Chronic NOAEC(ppm)(endpoint affected)Acute Oral LD50(ppm)Chronic NOAEC(ppm)(endpoint affected)*indicates valuerepresents NOAELAcute Contact LD50(ppm)Northern bobwhite,mallard or zebrafinchNorthern bobwhiteor mallardNorthern bobwhiteor mallardRat Rat or rabbit HoneybeeBensulfuron-methyl >2150 >5620 NA >5000750(adult bodyweight)>12.5Chlorimuron-ethyl >2510 >5620 180 >500025017*(reproduction)12.5Chlorsulfuron >5000 >5000174(reproduction)>5000100*(growth anddecreasedbodyweight)>25Flazasulfuron >2000 >5589484(hatchling survivaland adult malebodyweight)5000473(none)>100Foramsulfuron >2000 >44381000(none)>500015000(none)>1.9Halosulfuron-methyl >2210 >56201010(not indicated)317050*(not indicated)98.2ImazosulfuronIodosulfuron-methylNa>1744 >4360372(Adult male weightgain)2448500*(pup mortality)>81(Acute oral LC50)Mesosulfuron-methyl >2000 >4750>990(not indicated)>50001175*(reproduction)>13Metsulfuron-methyl >2150 >5620209(hatchling survivaland hatchlingweight)>5000500(adult bodyweight)>25Nicosulfuron >2126 >5311 NA >5000 5000 >20Orthosulfamuron >1960 NA1280(HDT)>5000100(growth)>100Page318of318Primisulfuron-methyl >2150 >5000500(none)>50501000(pup weight)>100Prosulfuron 1094 >500028(reproduction)54650(growth)>100Rimsulfuron >2000 >56201250(none)>5000165*(not indicated)>100Sulfometuron-methyl >4650 >4600 NA >5000300*(not indicated)>100Sulfosulfuron >2250 >5620245(14-daybodyweight)>50005000312*(bodyweight)>25Thifensulfuronmethyl>2510 >5+20250(number eggs andhatchlings)>50002500180*(none)>12.5Triasulfuron >2150 >50001000HDT>50001000(reducedbodyweight)>100Tribenuron-methyl >2250 >562030(14-day survival)>50005000312*(bodyweight)>100Trifloxysulfuron-Na >2250 >5800106(number ofhatchlings alive at 3week egg set)>37501000*(decreased weightgain)>25Triflusulfuronmethyl>2250 >5620250(not indicated)>50001500*(not indicated)>25