Exhibit
10.1

  

14755 Preston Road,
Suite 105


Dallas, Texas 75254



September
16, 2022


BY
EMAIL

Jody Staggs


Dear Jody,


SWK
Holdings Corporation (the “Company”) is pleased
to extend this offer letter to you in connection with your appointment as the Company’s President, effective September 1, 2022,
and Interim Chief Executive Officer, effective September 30, 2022. The terms contained herein will be effective through December 31,
2022. We look forward to engaging with you in the near term regarding entering into an employment agreement for January 2023 forward.
The terms of this offer letter are as follows:


		·	Annual
                                            Base Salary: $350,000, effective as of September
                                            1, 2022, payable in accordance with the Company’s ordinary payroll practices as established
                                            from time to time.



		·	2022
                                            Annual Bonus: You will be eligible to receive up
                                            to 35% of the bonus pool of the Company as determined by the Board and in which you currently
                                            participate. This bonus pool represents the aggregate potential bonus award for the Company’s
                                            entire executive team and will be calculated using all existing methodologies.



		·	Restricted
                                            Stock Award: You will be eligible to receive an
                                            award of shares of restricted Common Stock of the Company with a value equal to $400,000
                                            based on the Company’s closing share price as of September 1, 2022 (which is equal
                                            to 23,655 shares) pursuant to the Company’s 2010 Equity Incentive Plan (the “Award”),
                                            subject to the approval of the Company’s board of directors. The Award shall vest ratably
                                            on each of the first four anniversaries of the Award’s date of grant and be subject
                                            to the terms and conditions of the grant agreement pursuant to which is granted, including
                                            restrictive covenants.



Nothing
in this letter changes the “at will” status of your employment with the Company, which notwithstanding any other agreement
or arrangement can only be changed by the Board, nor modifies any restrictive covenants in favor of the Company to which you are subject.


If
you agree with the terms of this letter, we ask that you please sign and date this letter and return an executed copy to me. We look
forward to you continuing to be a part of our team.


[Signature
page to follow]




     


     

    

Sincerely,


SWK
HOLDINGS CORPORATION


 


	By:	/s/ Wendy F. DiCicco 	 
	Name: Wendy F.
DiCicco
	Title: Member of the Board, Compensation Committee Chair





Agreed
to and accepted:


Jody Staggs


 


	Signature: 	/s/ Jody Staggs	 



Date: September
19, 2022


 


[Signature Page to
Offer Letter]