Unassociated Document


     

    GUARANTOR
      GENERAL SECURITY AGREEMENT

     

    This
      Guarantor General Security Agreement (the “Agreement”)
      is
      dated January 31, 2006 by and among Acura Pharmaceutical Technologies, Inc.,
      an
      Indiana corporation with its principal place of business at 16235 State Road
      17,
      Culver, Indiana, 46511 (“APT”
or
      the
“Guarantor”),
      and
      Galen Partners III, L.P., a Delaware limited partnership with its principal
      place of business at 610 Fifth Avenue, Fifth Floor, New York, New York, 10020,
      acting in its capacity as agent for the Lenders, as defined below (the
“Agent”),
      for
      the benefit of the Lenders.

     

    PRELIMINARY
      STATEMENTS

     

    A. Acura
      Pharmaceuticals, Inc. (the “Company”)
      has
      entered into a Loan Agreement of even date herewith (as the same may be amended,
      modified, supplemented or restated from time to time, the “Loan
      Agreement;”
terms
      which are capitalized in this Agreement and not otherwise defined shall have
      the
      meanings ascribed to them in the Loan Agreement) with the Lenders party thereto
      (the “Lenders”).

     

    B. The
      Guarantor has executed and delivered to Agent, for the benefit of the Lenders,
      a
      Continuing Unconditional Secured Guaranty of even date herewith (a “Guaranty”)
      of the
      Company’s obligations under the Loan Agreement (collectively, the “Obligations”).

     

    C. The
      Lenders have required, as a condition precedent to the effectiveness of the
      Loan
      Agreement, that Guarantor (a) grant to the Agent, for the ratable benefit of
      the
      Lenders, a security interest in and to the Collateral (as defined in Section
      2.1
      below) and (b) execute and deliver this Agreement in order to secure the payment
      and performance by Guarantor of the Guaranty.

     

    AGREEMENT

     

    In
      consideration of the premises and in order to induce the Lenders to enter into
      and perform the Loan Agreement, Guarantor hereby agrees as follows:

     

    ARTICLE
      1

     

    CREATION
      OF SECURITY INTEREST

     

    1.1  SECURITY
      INTEREST

     

    Guarantor
      hereby pledges, assigns and grants to the Agent a continuing perfected lien
      and
      security interest having priority over any and all other security interests
      in
      all of Guarantor’s right, title and interest in and to the Collateral (as
      defined in Section 2.1 below) in order to secure the payment and performance
      of
      all Obligations owing by Guarantor.

     

    1.2  GUARANTOR
      REMAINS LIABLE

     

    Anything
      herein to the contrary notwithstanding, (a) the Guarantor shall remain liable
      under the contracts and agreements included in the Collateral to the extent
      set
      forth therein to perform all of its duties and obligations thereunder to the
      same extent as if this Agreement had not been executed, (b) the exercise by
      the
      Agent of any of the rights hereunder shall not release the Guarantor from any
      of
      its duties or obligations under the contracts and agreements included in the
      Collateral and (c) neither the Agent nor any Lender shall have any obligation
      or
      liability under the contracts and agreements included in the Collateral by
      reason of this Agreement, the Loan Agreement or any other Transaction Document,
      nor shall the Agent or any Lender be obligated to perform any of the obligations
      or duties of the Guarantor thereunder or to take any action to collect or
      enforce any claim for payment assigned hereunder.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    ARTICLE
      2

     

    COLLATERAL

     

    2.1  COLLATERAL

     

    For
      purposes of this Agreement, the term “Collateral”
shall
      mean, all of the assets of the Guarantor including all of the kinds and types
      of
      property described in clauses (a) through (g) of this Section 2.1, whether
      now
      owned or hereafter at any time arising, acquired or created by Guarantor and
      wherever located, and includes all replacements, additions, accessions,
      substitutions, repairs, proceeds and products relating thereto or therefrom,
      and
      all documents, ledger sheets and files of Guarantor relating thereto and all
      Proceeds (as defined in Section 2.2 below) of Collateral:

     

    (a)  all
      of
      Guarantor’s accounts, whether now existing or existing in the future, including
      without limitation (i) all accounts receivable (whether or not specifically
      listed on schedules furnished to the Agent), including, without limitation,
      all
      accounts created by or arising from all of Guarantor’s sales of goods or
      rendition of services made under any of Guarantor’s trade names, or through any
      of its divisions, (ii) all unpaid seller’s rights (including rescission,
      replevin, reclamation and stoppage in transit) relating to the foregoing or
      arising therefrom, (iii) all rights to any goods represented by any of the
      foregoing, including returned or repossessed goods, (iv) all reserves and credit
      balances held by Guarantor with respect to any such accounts receivable or
      account debtors, (v) all health-care-insurance receivables, and (vi) all
      guarantees or collateral for any of the foregoing (all of the foregoing property
      and similar property being hereinafter referred to as “Accounts”);

     

    (b)  all
      of
      Guarantor’s inventory, including without limitation (i) all raw materials, work
      in process, parts, components, assemblies, supplies and materials used or
      consumed in Guarantor’s businesses, wherever located and whether in the
      possession of Guarantor or any other Person; (ii) all goods, wares and
      merchandise, finished or unfinished, held for sale or lease or leased or
      furnished or to be furnished under contracts of service, wherever located and
      whether in the possession of Guarantor or any other person or entity; and (iii)
      all goods returned to or repossessed by Guarantor (all of the foregoing property
      being hereinafter referred to as “Inventory”);

     

    (c)  all
      of
      the equipment owned or leased by Guarantor, including, without limitation,
      machinery, equipment, office equipment and supplies, computers and related
      equipment, furniture, furnishings, tools, tooling, jigs, dies, fixtures,
      manufacturing implements, fork lifts, trucks, trailers, motor vehicles, and
      other equipment (all of the foregoing property being hereinafter referred to
      as
“Equipment”);

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    (d)  all
      of
      Guarantor’s general intangibles (including, without limitation, payment
      intangibles), instruments, securities (including without limitation United
      States of America Treasury Bills), credits, claims, demands, documents, letters
      of credit and letter of credit proceeds, documents of title, certificates of
      title, certificates of deposit, warehouse receipts, bills of lading, leases
      which are permitted to be assigned or pledged, deposit accounts, money, tax
      refund claims, and contract rights which are permitted to be assigned or pledged
      (all of the foregoing property being hereinafter referred to as “Intangibles”);

     

    (e)  all
      of
      Guarantor’s intellectual property, including, without limitation, New Drug
      Applications, Investigatory New Drug Applications, Abbreviated New Drug
      Applications, Alternative New Drug Applications, registrations and quotas as
      issued by the DEA or the Attorney General of the United States pursuant to
      the
      CSA, certifications, permits and approvals of federal and state governmental
      agencies, patents, patent applications, trademarks, trademark applications,
      service marks, service mark applications, trade names, domain names, technical
      knowledge and processes, formal or informal licensing arrangements which are
      permitted to be assigned or pledged, blueprints, technical specifications,
      computer software, programs, databases, copyrights, copyright applications
      and
      all confidential and proprietary information, including, without limitation,
      know-how, trade secrets, manufacturing and production processes and techniques,
      inventions, research and development information, databases and data, including,
      without limitation, technical data, financial and marketing and business data,
      customer lists, supplier lists, pricing and cost information and business and
      marketing plans, and all embodiments thereof, and rights thereto, including,
      without limitation, all of Guarantor’s rights to use the patents, trademarks,
      copyrights, service marks, or other property of the aforesaid nature of other
      Persons now or hereafter licensed to Guarantor, together with the goodwill
      of
      the business symbolized by or connected with Guarantor’s trademarks, copyrights,
      service marks, licenses and the other rights included in this Section 2.1(e)
      (all of the foregoing property being hereinafter referred to as “Intellectual
      Property”);
      

     

    (f)  all
      deposit accounts, letter-of-credit rights, instruments (including, without
      limitation, promissory notes), investment property and chattel paper;
      and

     

    (g)  all
      interest, dividends, distributions, cash, instruments and other property from
      time to time received, receivable or otherwise distributed in respect of or
      in
      exchange for any or all of the then existing Collateral.

     

    
      
        
        

      

      
        2

        
          

        

      

      
        
        

      

    

    2.2  PROCEEDS

     

    For
      purposes of this Agreement, the term “Proceeds”
shall
      include (a) whatever is now or hereafter received by Guarantor upon the sale,
      exchange, collection or other disposition of any item of Collateral, whether
      such proceeds constitute Inventory, Accounts, Intangibles, royalties, payment
      under insurance (whether or not the Agent is the loss payee thereof), or any
      indemnities, warranties or guaranties, payable by reason of loss or damage
      to or
      otherwise with respect to any or the foregoing Collateral, and (b) any such
      items which are now or hereafter acquired by Guarantor with any proceeds of
      Collateral hereunder.

     

    ARTICLE
      3

     

    REPRESENTATIONS
      AND WARRANTIES

     

    Guarantor
      represents and warrants as follows:

     

    3.1  ORGANIZATION
      AND EXISTENCE

     

    Guarantor
      is a corporation duly organized, validly existing and in good standing under
      the
      laws of its state of incorporation and is qualified to do business in such
      other
      jurisdictions as the nature or conduct of its operations or the ownership of
      its
      properties require such qualification. Guarantor does not own or lease any
      property or engage in any activity in any jurisdiction that might require
      qualification to do business as a foreign corporation in such jurisdiction
      and
      where the failure to so qualify could reasonably be expected to have a Material
      Adverse Effect or subject Guarantor to a material liability.

     

    3.2  AUTHORIZATION

     

    (a)  Guarantor
      has all requisite corporate power and authority (i) to execute and deliver,
      and
      to perform and observe its obligations under, the Transaction Documents to
      which
      it is a party, and (ii) to consummate the transactions contemplated hereby
      and
      thereby, including, without limitation, the grant of any security interest,
      mortgage, payment trust, guaranty or other security arrangement by Guarantor
      in,
      on or in respect of the Collateral.

     

    (b)  All
      corporate action on the part of Guarantor and its directors and stockholders
      necessary for the authorization, execution,
      delivery and performance by Guarantor of this Agreement, the Guaranty by
      Guarantor in favor of Agent, and the transactions contemplated therein or in
      any
      other Transaction Document to which it is a party, has been taken.

     

    3.3  PLACES
      OF BUSINESS

     

    Guarantor
      has no places of business, or warehouses in which it leases space, other than
      those set forth on Section
      3.3 of Schedule A,
      a copy
      of which is attached hereto and made a part hereof (“Schedule
      A”).

     

    
      
        
        

      

      
        3

        
          

        

      

      
        
        

      

    

    3.4  LOCATION
      OF COLLATERAL

     

    Except
      for the movement of Collateral from time to time from one place of business
      or
      warehouse listed on Section
      3.3 of Schedule A
      to
      another place of business or warehouse listed on Section
      3.3 of Schedule A,
      the
      Collateral is located at Guarantor’s chief executive offices or other places of
      business or warehouses listed on Section
      3.3 of Schedule A,
      and not
      at any other location.

     

    3.5  RESTRICTIONS
      ON COLLATERAL DISPOSITION

     

    Except
      for any restrictions imposed under the Guarantors General Security Agreement
      dated as of March 29, 2000 given by the Guarantor in connection with the Senior
      Note (the “Watson
      Guarantors Security Agreement”),
      the
      Guarantors General Security Agreement dated as of June 22, 2005 given by the
      Guarantors in connection with a certain Loan Agreement, dated of even date
      therewith (“June
      Bridge Loan Guarantors Security Agreement”),
      the
      Guarantors General Security Agreement dated as of September 16, 2005 given
      by
      the Guarantors in connection with a certain Loan Agreement, dated of even date
      therewith (“September
      Bridge Loan Guarantors Security Agreement”)
      and
      the Guarantors General Security Agreement dated as of November 9, 2005 given
      by
      the Guarantors in connection with a certain Loan Agreement, dated of even date
      therewith (“November
      Bridge Loan Guarantors Security Agreement”),
      none
      of the Collateral is subject to contractual obligations that may restrict or
      inhibit the Agent’s rights or ability to sell or dispose of the Collateral or
      any part thereof after the occurrence of an Event of Default.

     

    3.6  STATUS
      OF ACCOUNTS

     

    Each
      Account is based on an actual and bona fide rendition of services or sale of
      goods or products to customers, made by Guarantor in the ordinary course of
      its
      business. The Accounts created are Guarantor’s exclusive property and are not
      and shall not be subject to any lien, consignment arrangement, encumbrance,
      security interest or financing statement whatsoever, except (i) the lien in
      favor of the holders of the Senior Note under the Watson Term Loan and the
      documents executed in connection therewith, including, without limitation,
      the
      Watson Guarantors Security Agreement, (ii) the lien in favor of the holders
      of
      the Secured Promissory Notes issued in connection with a bridge loan (the
“June
      Bridge Loan”)
      extended pursuant to the terms of that certain Loan Agreement, dated as of
      June
      22, 2005 and the documents executed in connection therewith, including, without
      limitation, the June Bridge Loan Guarantors Security Agreement, (iii) the lien
      in favor of the holders of the Secured Promissory Notes issued in connection
      with a bridge loan (the “September
      Bridge Loan”)
      extended pursuant to the terms of that certain Loan Agreement, dated as of
      September 16, 2005 and the documents executed in connection therewith,
      including, without limitation, the September Bridge Loan Guarantors Security
      Agreement and (iv) the lien in favor of the holders of the Secured Promissory
      Notes issued in connection with a bridge loan (the “November
      Bridge Loan”)
      extended pursuant to the terms of that certain Loan Agreement, dated as of
      November 9, 2005 and the documents executed in connection therewith, including,
      without limitation, the November Bridge Loan Guarantors Security Agreement.
      To
      the best knowledge of Guarantor, Guarantor’s customers have accepted the goods,
      products and services and owe and are obligated to pay the full amounts stated
      in the invoices according to their terms, without any dispute, offset, defense
      or counterclaim.

     

    
      
        
        

      

      
        4

        
          

        

      

      
        
        

      

    

    3.7  COPYRIGHTS,
      TRADEMARKS AND PATENTS

     

    (a)  Guarantor
      owns outright all of the Intellectual Property Rights listed on Section
      4.12
      of the
      Schedule of Exceptions attached to the Loan Agreement free and clear of all
      liens and encumbrances except for the Permitted Liens and pays no royalty to
      anyone under or with respect to any of them.

     

    (b)  Guarantor
      has not licensed to anyone the use of any of such Intellectual Property Rights
      and has no knowledge of the infringing use by the Company or any Guarantor
      of
      any Intellectual Property Rights of third parties.

     

    (c)  Other
      than as disclosed to the Company’s or the Guarantor’s Board of Directors,
      Guarantor has no knowledge, nor has it received any notice (i) of any conflict
      with the asserted rights of others with respect to any Intellectual Property
      Rights used in, or useful to, the operation of the business conducted by the
      Company and the Guarantor or with respect to any license under which the Company
      or Guarantor is licensor or licensee; or (ii) that the Intellectual Property
      Rights infringe upon the rights of any third party.

     

    (d)  Guarantor
      has made or performed all filings, recordings and other acts and has paid all
      required fees and taxes to maintain and protect its interest in each and every
      item of Intellectual Property in full force and effect throughout the world,
      and
      to protect and maintain its interest therein including, without limitation,
      recordations of any of its interests in patents and trademarks with the U.S.
      Patent and Trademark Office and in corresponding national and international
      patent offices, and recordation of any of its interests in any copyrights with
      the U.S. Copyright Office and in corresponding national and international
      copyright offices. Guarantor has used proper statutory notice in connection
      with
      its use of each patent, trademark and copyright.

     

    3.8  INVENTORY

     

    All
      Inventory of Guarantor consists of a quality and quantity usable and salable
      in
      the ordinary course of business, except for obsolete items and items of
      below-standard quality, all of which have been or will be written off or written
      down to net realizable value on the consolidated balance sheet of the Guarantor
      and its Subsidiaries as of March 31, 2005. The quantities of each type of
      Inventory (whether raw materials, work-in-process, or finished goods) are not
      excessive, but are reasonable and warranted in the present circumstances of
      Guarantor.

     

    3.9  OWNERSHIP

     

    Guarantor
      is the legal and beneficial owner of its Collateral free and clear of any lien,
      claim, option or right of others, except for the security interest created
      under
      this Agreement, the Watson Guarantors Security Agreement, the June Bridge Loan
      Guarantors Security Agreement, the September Bridge Loan Guarantors Security
      Agreement and the November Bridge Loan Guarantors Security Agreement. No
      effective financing statement or other instrument similar in effect covering
      all
      or any part of such Collateral or listing Guarantor or any trade name of
      Guarantor is on file in any recording office, except such as may have been
      filed
      relating to the Watson Term Loan, the June Bridge Loan, the September Bridge
      Loan and the November Bridge Loan. The Agent has, for the benefit of the
      Lenders, a valid and perfected security interest in the Collateral which
      security interest has priority over any and all other security interests in
      such
      Collateral.

     

    
      
        
        

      

      
        5

        
          

        

      

      
        
        

      

    

    


     

    ARTICLE
      4

     

    COVENANTS

     

    Guarantor
      agrees as follows:

     

    4.1  DEFEND
      AGAINST CLAIMS

     

    Guarantor
      will defend the Collateral against all claims and demands of all Persons at
      any
      time claiming the same or any interest therein unless both the Agent and
      Guarantor determine that the claim or demand is not material and that,
      consequently, such defense would not be consistent with good business judgment.
      Guarantor will not permit any lien notices with respect to the Collateral or
      any
      portion thereof to exist or be on file in any public office except for those
      in
      favor of the Agent and those permitted under the terms of the Loan
      Agreement.

     

    4.2  CHANGE
      IN COLLATERAL LOCATION

     

    Guarantor
      will not (a) change its corporate name, (b) change the location of its chief
      executive office or establish any place of business other than those specified
      in Section
      3.3 of Schedule A,
      or (c)
      move or permit movement of the Collateral from the locations specified therein
      except from one such location to another such location, unless in each case
      Guarantor shall have given the Agent at least thirty (30) days prior written
      notice thereof, and shall have, in advance, executed and caused to be filed
      or
      delivered to the Agent any financing statements or other documents required
      by
      the Agent to perfect the security interest of the Agent in the Collateral in
      accordance with Section 4.3 of this Agreement, all in form and substance
      satisfactory to the Agent.

     

    4.3  ADDITIONAL
      FINANCING STATEMENTS

     

    Promptly
      upon the reasonable request of the Agent, Guarantor will execute and deliver
      or
      use its best efforts to procure any document, give any notices, execute and
      file
      any financing statements, mortgages or other documents, all in form and
      substance satisfactory to the Agent, mark any chattel paper, deliver any chattel
      paper or instruments to the Agent and take any other actions that are necessary
      or, in the opinion of the Agent, desirable to perfect or continue the perfection
      and the first priority of the Agent’s security interest in the Collateral, to
      protect the Collateral against the rights, claims, or interests of third
      persons, or to effect the purposes of this Agreement. Guarantor will pay the
      costs incurred in connection with any of the foregoing.

     

    
      
        
        

      

      
        6

        
          

        

      

      
        
        

      

    

    4.4  ADDITIONAL
      LIENS; TRANSFERS

     

    Without
      the prior written consent of the Agent, Guarantor will not, in any way,
      hypothecate or create or permit to exist any lien, security interest, charge
      or
      encumbrance on or other interest in the Collateral, other than those permitted
      under the terms of the Loan Agreement and the liens in favor of the holders
      of
      the Senior Note pursuant to (i) the Watson Term Loan and documents relative
      thereto; (ii) the June Bridge Loan and the documents relative thereto; (iii)
      the
      September Bridge Loan and the documents relative thereto; and (iv) the November
      Bridge Loan and the documents relative thereto, and Guarantor will not sell,
      transfer, assign, pledge, collaterally assign, exchange or otherwise dispose
      of
      the Collateral, other than the sale of Inventory in the ordinary course of
      business and the sale of obsolete or worn out Equipment. Notwithstanding the
      foregoing, if the proceeds of any such sale consist of notes, instruments,
      documents of title, letters of credit or chattel paper, such proceeds shall
      be
      promptly delivered to the Agent to be held as Collateral hereunder. If the
      Collateral, or any part thereof, is sold, transferred, assigned, exchanged,
      or
      otherwise disposed of in violation of these provisions, the security interest
      of
      the Agent shall continue in such Collateral or part thereof notwithstanding
      such
      sale, transfer, assignment, exchange or other disposition, and Guarantor will
      hold the proceeds thereof for the benefit of the Agent, and promptly transfer
      such proceeds to the Agent in kind.

     

    4.5  CONTRACTUAL
      OBLIGATIONS

     

    Guarantor
      will not enter into any contractual obligations which may restrict or inhibit
      the Agent’s rights or ability to sell or otherwise dispose of the Collateral or
      any part thereof after the occurrence or during the continuance of an Event
      of
      Default.

     

    4.6  AGENT’S
      RIGHT TO PROTECT COLLATERAL

     

    Upon
      the
      occurrence or continuance of an Event of Default, the Agent shall have the
      right
      at any time to make any payments and do any other acts the Agent may deem
      necessary to protect the security interests of the Lenders in the Collateral,
      including, without limitation, the rights to pay, purchase, contest or
      compromise any encumbrance, charge or lien which, in the reasonable judgment
      of
      the Agent, appears to be prior to or superior to the security interests granted
      hereunder, and appear in and defend any action or proceeding purporting to
      affect its security interests in, or the value of, the Collateral. Guarantor
      hereby agrees to reimburse the Agent for all payments made and expenses incurred
      under this Agreement including reasonable fees, expenses and disbursements
      of
      attorneys and paralegals acting for the Agent, including any of the foregoing
      payments under, or acts taken to protect its security interests in, the
      Collateral, which amounts shall be secured under this Agreement, and agrees
      it
      shall be bound by any payment made or act taken by the Agent hereunder absent
      the Agent’s gross negligence or willful misconduct. The Agent shall have no
      obligation to make any of the foregoing payments or perform any of the foregoing
      acts.

     

    
      
        
        

      

      
        7

        
          

        

      

      
        
        

      

    

    4.7  FURTHER
      OBLIGATIONS WITH RESPECT TO ACCOUNTS

     

    In
      furtherance of the continuing assignment and security interest in the Accounts
      of Guarantor granted pursuant to this Agreement, upon the creation of Accounts,
      upon the Agent’s request, Guarantor will execute and deliver to the Agent in
      such form and manner as the Agent may require, solely for its convenience in
      maintaining records of Collateral, such confirmatory schedules of Accounts,
      and
      other appropriate reports designating, identifying and describing the Accounts
      as the Agent may reasonably require. In addition, upon the Agent’s request,
      Guarantor shall provide the Agent with copies of agreements with, or purchase
      orders from, the customers of Guarantor and copies of invoices to customers,
      proof of shipment or delivery and such other documentation and information
      relating to such Accounts and other Collateral as the Agent may reasonably
      require. Furthermore, upon the Agent’s request, Guarantor shall deliver to the
      Agent any documents or certificates of title issued with respect to any property
      included in the Collateral, and any promissory notes, letters of credit or
      instruments related to or otherwise in connection with any property included
      in
      the Collateral, which in any such case came into the possession of Guarantor,
      or
      shall cause the issuer thereof to deliver any of the same directly to the Agent,
      in each case with any necessary endorsements in favor of the Agent. Failure
      to
      provide the Agent with any of the foregoing shall in no way affect, diminish,
      modify or otherwise limit the security interests granted herein. Guarantor
      hereby authorizes the Agent to regard Guarantor’s printed name or rubber stamp
      signature on assignment schedules or invoices as the equivalent of a manual
      signature by Guarantor’s authorized officers or agents.

     

    4.8  INSURANCE

     

    Guarantor
      agrees to maintain public liability insurance, third party property damage
      insurance and replacement value insurance on the Collateral under such policies
      of insurance, with such insurance companies, in such amounts and covering such
      risks as are at all times satisfactory to the Agent in its commercially
      reasonable judgment. All policies covering the Collateral are to name the Agent
      as an additional insured and the loss payee in case of loss, and are to contain
      such other provisions as the Agent may reasonably require to fully protect
      the
      Agent’s interest in the Collateral and to any payments to be made under such
      policies. Without limiting the generality of the foregoing, all such policies
      shall contain standard lender’s loss payable clauses in favor of the Agent and
      shall provide that the same may not be cancelled, terminated or revised without
      giving the Agent at least 30 days prior written notice of such cancellation,
      termination or revision. Proceeds of such insurance policy or policies will
      be
      applied to the Obligations unless written consent to the contrary is obtained
      from the Agent. Guarantor will furnish the Agent with certificates of insurance
      or such other evidence satisfactory to the Agent so as to evidence compliance
      with the provisions of this Section.

     

    4.9  TAXES

     

    Guarantor
      agrees to pay, when due, all taxes lawfully levied or assessed against Guarantor
      or any of the Collateral before any penalty or interest accrues thereon;
provided,
      however,
      that,
      unless such taxes have become a federal tax or ERISA lien on any of the assets
      of Guarantor, no such tax need be paid if the same is being contested, in good
      faith, by appropriate proceedings promptly instituted and diligently conducted
      and if an adequate reserve or other appropriate provision shall have been made
      therefor as required in order to be in conformity with GAAP.

     

    
      
        
        

      

      
        8

        
          

        

      

      
        
        

      

    

    4.10  COMPLIANCE
      WITH LAWS

     

    Guarantor
      agrees to comply in all material respects with all Legal Requirements applicable
      to the Collateral or any part thereof, or to the operation of its business
      or
      its assets generally, unless Guarantor contests in good faith, by appropriate
      legal, administrative or other proceedings promptly instituted and diligently
      conducted, any such Legal Requirements in a reasonable manner and in good faith.
      Guarantor agrees to maintain in full force and effect, its respective licenses
      and permits granted by any governmental authority as may be necessary or
      advisable for Guarantor to conduct its business in all material respects.


     

    4.11  MAINTENANCE
      OF PROPERTY

     

    Guarantor
      agrees to keep all property useful and necessary to its business in good working
      order and condition (ordinary wear and tear excepted) and not to commit or
      suffer any waste with respect to any of its properties.

     

    4.12  ENVIRONMENTAL
      AND OTHER MATTERS

     

    Guarantor
      will conduct its business so as to comply in all respects with all
      environmental, land use, occupational, safety or health Legal Requirements
      in
      all jurisdictions in which it is or may at any time be doing business, except
      to
      the extent that Guarantor is contesting, in good faith by appropriate legal,
      administrative or other proceedings, promptly instituted and diligently
      conducted, any such Legal Requirement; provided,
      further,
      that
      Guarantor shall comply with the order of any court or other governmental
      authority relating to such Legal Requirements unless Guarantor shall currently
      be prosecuting an appeal, proceedings for review or administrative proceedings
      and shall have secured a stay of enforcement or execution or other arrangement
      postponing enforcement or execution pending such appeal, proceedings for review
      or administrative proceedings.

     

    4.13  INTELLECTUAL
      PROPERTY

     

    With
      respect to each item of its Intellectual Property, Guarantor agrees to take,
      at
      its expense, all necessary steps, including, without limitation, in the U.S.
      Patent and Trademark Office, the U.S. Copyright Office and any other
      governmental authority, to (a) maintain the validity and enforceability of
      such
      Intellectual Property and maintain such Intellectual Property in full force
      and
      effect, and (b) pursue the registration and maintenance of each patent,
      trademark, or copyright registration or application, now or hereafter included
      in such Intellectual Property of the Guarantor, including, without limitation,
      the payment of required fees and taxes, the filing of responses to office
      actions issued by the U.S. Patent and Trademark Office, the U.S. Copyright
      Office or other governmental authorities, the filing of applications for renewal
      or extension, the filing of affidavits under Sections 8 and 15 of the U.S.
      Trademark Act, the filing of divisional, continuation, continuation-in-part,
      reissue and renewal applications or extensions, the payment of maintenance
      fees
      and the participation in interference, reexamination, opposition, cancellation,
      infringement and misappropriation proceedings. Neither Guarantor shall, without
      the prior written consent of the Agent, discontinue use of or otherwise abandon
      any Intellectual Property, or abandon any right to file an application for
      any
      patent, trademark or copyright, unless Guarantor shall have previously
      determined that such use or the pursuit or maintenance of such Intellectual
      Property is no longer desirable in the conduct of Guarantor’s business and that
      the loss thereof would not be reasonably likely to have a Material Adverse
      Effect, in which case, Guarantor will give prompt notice of any such abandonment
      to the Agent.

     

    
      
        
        

      

      
        9

        
          

        

      

      
        
        

      

    

    4.14  FURTHER
      ASSURANCES

     

    Guarantor
      shall take all such further actions and execute all such further documents
      and
      instruments (including, but not limited to, collateral assignments of
      Intellectual Property and Intangibles or any portion thereof) as the Agent
      may
      at any time reasonably determine in its sole discretion to be necessary or
      desirable to further carry out and consummate the transactions contemplated
      by
      the Loan Agreement and the documentation relating thereto, including this
      Agreement, and to perfect or protect the liens (and the priority status thereof)
      of the Agent in the Collateral.

     

    ARTICLE
      5

     

    REMEDIES

     

    5.1  OBTAINING
      COLLATERAL UPON DEFAULT

     

    If
      any
      Event of Default shall have occurred and be continuing, then and in every such
      case, subject to the terms of the Loan Agreement and any mandatory requirements
      of applicable law then in effect, the Agent, in addition to any rights now
      or
      hereafter existing under applicable law, shall have all rights as a secured
      creditor under the Uniform Commercial Code in all relevant jurisdictions and
      may:

     

    (a)  personally,
      or by agents or attorneys, immediately retake possession of the Collateral
      or
      any part thereof, from any Guarantor or any other Person who then has possession
      of any part thereof, with or without notice or process of law, and for that
      purpose may enter upon Guarantor’s premises where any of the Collateral is
      located and remove the same and use in connection with such removal any and
      all
      services, supplies, aids and other facilities of Guarantor;

     

    (b)  instruct
      the obligor or obligors on any agreement, instrument or other obligation
      (including, without limitation, the Accounts) constituting the Collateral to
      make any payment required by the terms of such instrument or agreement directly
      to the Agent;

     

    (c)  withdraw
      all monies, securities and instruments held pursuant to any pledge arrangement
      for application to the Obligations;

     

    (d)  sell,
      assign or otherwise liquidate, or direct any Guarantor to sell, assign or
      otherwise liquidate, any or all of the Collateral or any part thereof, and
      take
      possession of the proceeds of any such sale or liquidation;

     

    
      
        
        

      

      
        10

        
          

        

      

      
        
        

      

    

    (e)  take
      possession of the Collateral or any part thereof, by directing any Guarantor
      in
      writing to deliver the same to the Agent at any place or places designated
      by
      the Agent, in which event Guarantor shall at its own expense:

     

    (1)  forthwith
      cause the same to be moved to the place or places so designated by the Agent
      and
      there delivered to the Agent,

     

    (2)  store
      and
      keep any Collateral so delivered to the Agent at such place or places pending
      further action by the Agent as provided in Section 5.2, and

     

    (3)  while
      the
      Collateral shall be so stored and kept, provide such guards and maintenance
      services as shall be necessary to protect the same and to preserve and maintain
      the Collateral in good condition;

     

    it
      being
      understood that any Guarantor’s obligation to so deliver the Collateral is of
      the essence of this Agreement and that, accordingly, upon application to a
      court
      of equity having jurisdiction, the Agent shall be entitled to a decree requiring
      specific performance by Guarantor of said obligation.

     

    5.2  DISPOSITION
      OF COLLATERAL

     

    Any
      Collateral repossessed by the Agent under or pursuant to Section 5.1 and any
      other Collateral whether or not so repossessed by the Agent may be sold,
      assigned, leased or otherwise disposed of under one or more contracts or as
      an
      entirety, and without the necessity of gathering at the place of sale the
      property to be sold, and in general in such manner, at such time or times,
      at
      such place or places and on such terms as the Agent may, in compliance with
      any
      mandatory requirements of applicable law, determine to be commercially
      reasonable. Any of the Collateral may be sold, leased or otherwise disposed
      of,
      in the condition in which the same existed when taken by the Agent or after
      any
      overhaul or repair which the Agent shall determine to be commercially
      reasonable. Any such disposition which shall be a private sale or other private
      proceedings permitted by such requirements shall be made upon not less than
      ten
      (10) days’ written notice to Guarantor specifying the time at which such
      disposition is to be made and the intended sale price or other consideration
      therefor, and shall be subject, for the ten (10) days after the giving of such
      notice, to the right of Guarantor or any nominee of Guarantor to acquire the
      Collateral involved at a price or for such other consideration at least equal
      to
      the intended sale price or other consideration so specified. Any such
      disposition which shall be a public sale permitted by such requirements shall
      be
      made upon not less than ten (10) days’ written notice to Guarantor specifying
      the time and place of such sale and, in the absence of applicable requirements
      of law, shall be by public auction (which may, at the option of the Agent,
      be
      subject to reserve), after publication at least once in The
      New York Times
      not less
      than ten (10) days prior to the date of sale. If The
      New York Times
      is not
      then being published, publication may be made in lieu thereof in any newspaper
      then being circulated in the City of New York, New York, as the Agent may elect.
      All requirements of reasonable notice under this Section 5.2 shall be met if
      such notice is mailed, postage prepaid at least ten (10) days before the time
      of
      such sale or disposition, to the Guarantor at its address set forth herein
      or
      such other address as the Guarantor may have, in writing, provided to the Agent.
      The Agent may, if it deems it reasonable, postpone or adjourn any sale of any
      Collateral from time to time by an announcement at the time and place of the
      sale to be so postponed or adjourned without being required to give a new notice
      of sale. The proceeds realized from the sale of any Collateral shall be applied
      as follows: first, to the reasonable costs, expenses and attorneys’ fees and
      expenses incurred by Agent for collection and for acquisition, completion,
      protection, removal, storage, sale and delivery of the Collateral; second,
      to
      interest due on any of the Obligations and any fees payable under this
      Agreement; and third, to the principal of the Obligations. If any deficiency
      shall arise, Guarantor shall remain liable to Agent and Lenders
      therefor.

     

    
      
        
        

      

      
        11

        
          

        

      

      
        
        

      

    

     

    5.3  POWER
      OF ATTORNEY

     

    Guarantor
      hereby irrevocably authorizes and appoints the Agent, or any Person or agent
      the
      Agent may designate, as Guarantor’s attorney-in-fact, at Guarantor’s cost and
      expense, subject to the terms of the Loan Agreement, to exercise all of the
      following powers upon and at any time after the occurrence and during the
      continuance of an Event of Default, which powers, being coupled with an
      interest, shall be irrevocable until all of the Obligations owing by Guarantor
      shall have been paid and satisfied in full:

     

    (a)  accelerate
      or extend the time of payment, compromise, issue credits, bring suit or
      administer and otherwise collect Accounts or proceeds of any
      Collateral;

     

    (b)  receive,
      open and dispose of all mail addressed to Guarantor and notify postal
      authorities to change the address for delivery thereof to such address as the
      Agent may designate;

     

    (c)  give
      customers indebted on Accounts notice of the Agent’s interest therein, or to
      instruct such customers to make payment directly to the Agent for Guarantor’s
      account;

     

    (d)  convey
      any item of Collateral to any purchaser thereof;

     

    (e)  give
      any
      notices or record any liens under Section 4.3 hereof; and 

     

    (f)  make
      any
      payments or take any acts under Section 4.6 hereof.

     

    The
      Agent’s authority under this 5.3 shall include, without limitation, the
      authority to execute and give receipt for any certificate of ownership or any
      document, transfer title to any item of Collateral, sign Guarantor’s name on all
      financing statements or any other documents deemed necessary or appropriate
      to
      preserve, protect or perfect the security interest in the Collateral and to
      file
      the same, prepare, file and sign Guarantor’s name on any notice of lien,
      assignment or satisfaction of lien or similar document in connection with any
      Account and prepare, file and sign Guarantor’s name on a proof of claim in
      bankruptcy or similar document against any customer of Guarantor, and to take
      any other actions arising from or incident to the rights, powers and remedies
      granted to the Agent in this Agreement. This power of attorney is coupled with
      an interest and is irrevocable by Guarantor.

     

    
      
        
        

      

      
        12

        
          

        

      

      
        
        

      

    

    5.4  WAIVER
      OF CLAIMS

     

    Except
      as
      otherwise provided in this Agreement, GUARANTOR HEREBY WAIVES, TO THE EXTENT
      PERMITTED BY APPLICABLE LAW, NOTICE AND JUDICIAL HEARING IN CONNECTION WITH
      THE
      AGENT’S OR ANY LENDER’S TAKING POSSESSION OF OR DISPOSING OF ANY OF THE
      COLLATERAL, INCLUDING, WITHOUT LIMITATION, ANY AND ALL PRIOR NOTICE AND HEARING
      FOR ANY PREJUDGMENT REMEDY OR REMEDIES AND ANY SUCH RIGHT WHICH ANY GUARANTOR
      WOULD OTHERWISE HAVE UNDER THE CONSTITUTION OR ANY STATUTE OF THE UNITED STATES
      OR OF ANY STATE, and Guarantor hereby further waives, to the extent permitted
      by
      law:

     

    (a)  all
      damages occasioned by such taking of possession except any damages which are
      the
      direct result of the Agent’s or Lender’s gross negligence or willful
      misconduct;

     

    (b)  all
      other
      requirements as to the time, place and terms of sale or other requirements
      with
      respect to the enforcement of the Agent’s or Lender’s rights hereunder, except
      as expressly provided herein; and

     

    (c)  all
      rights of redemption, appraisement, valuation, stay, extension or moratorium
      now
      or hereafter in force under any applicable law in order to prevent or delay
      the
      enforcement of this Agreement or the absolute sale of the Collateral or any
      portion thereof, and Guarantor, for itself and all who may claim under it,
      insofar as it or they now or hereafter lawfully may, hereby waives the benefit
      of all such laws.

     

    Any
      sale
      of, or the grant of options to purchase, or any other realization upon any
      Collateral shall operate to divest all right, title, interest, claim and demand,
      either at law or in equity, of Guarantor therein and thereto, and shall be
      a
      perpetual bar both at law and in equity against Guarantor and against any and
      all persons claiming or attempting to claim the Collateral so sold, optioned
      or
      realized upon, or any part thereof, from, through and under
      Guarantor.

     

    5.5  REMEDIES
      CUMULATIVE

     

    Each
      and
      every right, power and remedy hereby specifically given to the Agent shall
      be in
      addition to every other right, power and remedy specifically given under this
      Agreement, under the Loan Agreement or under other documentation relating
      thereto or now or hereafter existing at law or in equity, or by statute, and
      each and every right, power and remedy whether specifically herein given or
      otherwise existing may be exercised from time to time or simultaneously and
      as
      often and in such order as may be deemed expedient by the Agent. All such
      rights, powers and remedies shall be cumulative and the exercise or the
      beginning of exercise of one shall not be deemed a waiver of the right to
      exercise of any other or others. No delay or omission of the Agent in the
      exercise of any such right, power or remedy and no renewal or extension of
      any
      of the Obligations shall impair any such right, power or remedy or shall be
      construed to be a waiver of any default or Event of Default or any acquiescence
      therein.

     

    
      
        
        

      

      
        13

        
          

        

      

      
        
        

      

    

    


    ARTICLE
      6

     

    MISCELLANEOUS
      PROVISIONS

     

    6.1  NOTICES

     

    All
      notices, approvals, consents or other communications required or desired to
      be
      given hereunder shall be delivered in person, by facsimile transmission followed
      promptly by first class mail, by a nationally recognized courier service marked
      for next business day delivery or by overnight mail, and delivered if to the
      Agent, then to the attention of Bruce F. Wesson, c/o Galen Partners III, L.P.,
      610 Fifth Avenue, Fifth Floor, New York, New York, 10020, fax no. (212)
      218-4990, with a copy to George N. Abrahams, Esq., c/o Blank Rome, LLP, Chrysler
      Building, 405 Lexington Avenue, New York, New York 10174, fax no. (917)
      332-3763, and if to the Guarantor, then to c/o Acura Pharmaceuticals, Inc.,
      attention of Mr. Andrew D. Reddick, 616 N. North Court, Suite 120, Palatine,
      Illinois 60067, with a copy to John P. Reilly, Esq., St. John & Wayne,
      L.L.C., 2 Penn Plaza East, Newark, New Jersey, 07105, fax no. (973)
      491-3555.

     

    6.2  HEADINGS

     

    The
      headings in this Agreement are for purposes of reference only and shall not
      affect the meaning or construction of any provision of this
      Agreement.

     

    6.3  SEVERABILITY

     

    The
      provisions of this Agreement are severable, and if any clause or provision
      shall
      be held invalid or unenforceable in whole or in part in any jurisdiction, then
      such invalidity or unenforceability shall affect, in that jurisdiction only,
      such clause or provision, or part thereof, and shall not in any manner affect
      such clause or provision in any other jurisdiction or any other clause or
      provision of this Agreement in any jurisdiction.

     

    6.4  AMENDMENTS,
      WAIVERS AND CONSENTS

     

    Any
      amendment or waiver of any provision of this Agreement and any consent to any
      departure by any Guarantor from any provision of this Agreement shall be
      effective only if made or given in writing signed by the Agent.

     

    6.5  INTERPRETATION
      OF AGREEMENT

     

    All
      terms
      not defined herein or in the Loan Agreement shall have the meaning set forth
      in
      the applicable Uniform Commercial Code. Acceptance of or acquiescence in a
      course of performance rendered under this Agreement shall not be relevant in
      determining the meaning of this Agreement even though the accepting or
      acquiescing party had knowledge of the nature of the performance and opportunity
      for objection.

     

    
      
        
        

      

      
        14

        
          

        

      

      
        
        

      

    

    6.6  CONTINUING
      SECURITY INTEREST

     

    This
      Agreement shall create a continuing security interest in the Collateral and
      shall (a) remain in full force and effect, (b) be binding upon Guarantor, and
      its successors and assigns and (b) inure to the benefit of the Agent and its
      successors and assigns.

     

    6.7  REINSTATEMENT

     

    To
      the
      extent permitted by law, this Agreement shall continue to be effective or be
      reinstated if at any time any amount received by the Agent in respect of the
      Obligations owing by the Guarantor is rescinded or must otherwise be restored
      or
      returned by the Agent upon the occurrence or during the pendency of any Event
      of
      Default, all as though such payments had not been made.

     

    6.8  SURVIVAL
      OF PROVISIONS

     

    All
      representations, warranties and covenants of the Guarantor contained herein
      shall survive the execution and delivery of this Agreement, and shall terminate
      only upon the full and final indefeasible payment and performance by the
      Guarantor of the Obligations secured hereby.

     

    6.9  SETOFF

     

    The
      Agent
      shall have all rights of setoff available at law or in equity.

     

    6.10  POWER
      OF ATTORNEY

     

    In
      addition to the powers granted to the Agent under Section 5.3, Guarantor hereby
      irrevocably authorizes and appoints the Agent, or any Person or agent the Agent
      may designate, as Guarantor’s attorney-in-fact, at Guarantor’s cost and expense,
      to exercise all of the following powers, which being coupled with an interest,
      shall be irrevocable until all of the Obligations shall have been indefeasibly
      paid and satisfied in full:

     

    (a)  after
      the
      occurrence of an Event of Default, to receive, take, endorse, sign, assign
      and
      deliver, all in the name of the Agent or Guarantor, any and all checks, notes,
      drafts, and other documents or instruments relating to the Collateral;
      and

     

    (b)  to
      request, at any time from customers indebted on Accounts, verification of
      information concerning the Accounts and the amounts owing thereon.

     

    6.11  INDEMNIFICATION;
      AUTHORITY OF AGENT

     

    Neither
      the Agent or any Lender nor any director, officer, employee, attorney or agent
      of the Agent or any Lender shall be liable to Guarantor for any action taken
      or
      omitted to be taken by it or them hereunder, except for its or their own gross
      negligence or willful misconduct, nor shall the Agent or any Lender be
      responsible for the validity, effectiveness or sufficiency of this Agreement
      or
      of any document or security furnished pursuant hereto. The Agent, the Lenders
      and their respective directors, officers, employees, attorneys and agents shall
      be entitled to rely on any communication, instrument or document reasonably
      believed by it or them to be genuine and correct and to have been signed or
      sent
      by the proper person or persons. Guarantor agrees to indemnify and hold harmless
      the Agent, the Lenders and any other person from and against any and all costs,
      expenses (including reasonable fees, expenses and disbursements of attorneys
      and
      paralegals (including, without duplication, reasonable charges of inside
      counsel)), claims or liability incurred by the Agent, any Lender or such person
      hereunder, unless such claim or liability shall be due to willful misconduct
      or
      gross negligence on the part of the Agent, the Lender or such
      person.

     

    
      
        
        

      

      
        15

        
          

        

      

      
        
        

      

    

    6.12  RELEASE;
      TERMINATION OF AGREEMENT

     

    Subject
      to the provisions of Section 6.7 of this Agreement, this Agreement shall
      terminate upon the termination of the Guaranty and the full and final
      indefeasible payment and performance of all the Obligations owing by Guarantor.
      At such time, the Agent shall, at the request of any Guarantor, reassign and
      redeliver to Guarantor all of the Collateral hereunder which has not been sold,
      disposed of, retained or applied by the Agent in accordance with the terms
      hereof. Such reassignment and redelivery shall be without warranty by or
      recourse to the Agent, except as to the absence of any prior assignments by
      the
      Agent of its interest in the Collateral, and shall be at the expense of
      Guarantor.

     

    6.13  COUNTERPARTS

     

    This
      Agreement may be executed in one or more counterparts, including by facsimile
      copy, each of which shall be deemed an original but all of which shall together
      constitute one and the same agreement.

     

    6.14  GOVERNING
      LAW

     

    This
      Agreement and the rights of the parties hereunder shall be governed by, and
      construed in accordance with, the laws of the State of New York wherein the
      terms of this Agreement were negotiated, excluding to the greatest extent
      permitted by law any rule of law that would cause the application of the laws
      of
      any jurisdiction other than the State of New York.

     

    6.15  SUBMISSION
      TO JURISDICTION

     

    (a)  Each
      of
      the parties hereto hereby irrevocably and unconditionally submits, for itself
      and its property, to the nonexclusive jurisdiction of any New York State court
      or United States Federal court sitting in New York City, and any appellate
      court
      from any thereof, in any action or proceeding arising our of or relating to
      this
      Agreement or any of the other Transaction Documents to which it is a party,
      or
      for recognition or enforcement of any judgment, and each of the parties hereto
      irrevocably and unconditionally agrees that all claims in respect of any such
      action or proceeding may be heard and determined in any such New York State
      court or, to the fullest extent permitted by law, in such United States Federal
      court. Each of the parties hereto agrees that a final judgment in any such
      action or proceeding shall be conclusive and may be enforced in other
      jurisdictions by suit on the right that any party may otherwise have to bring
      any action or proceeding relating to this Agreement or any of the other
      Transaction Documents in the courts of any other jurisdiction. 

     

    
      
        
        

      

      
        16

        
          

        

      

      
        
        

      

    

    (b)  Each
      of
      the parties hereto irrevocably and unconditionally waives, to the fullest extent
      it may legally and effectively do so, any objection that it may now or hereafter
      have to the laying of venue of any suit, action or proceeding arising out of
      or
      in relation to this Agreement or any other Transaction Document to which it
      is a
      party in any such New York State or United States Federal court sitting in
      New
      York City. Each of the parties hereto hereby irrevocably waives, to the fullest
      extent permitted by law, the defense of an inconvenient forum to the maintenance
      of such action or proceeding in any such court.

     

    6.16  SERVICE
      OF PROCESS

     

    GUARANTOR
      HEREBY IRREVOCABLY AGREES THAT SERVICE OF PROCESS IN ANY LEGAL ACTION OR
      PROCEEDING WITH RESPECT TO THIS AGREEMENT MAY BE EFFECTED BY MAILING A COPY
      THEREOF BY REGISTERED OR CERTIFIED MAIL, POSTAGE PREPAID, TO GUARANTOR AT ITS
      ADDRESS SET FORTH IN SECTION 6.1 HEREOF. 

     

    6.17  LIMITATION
      OF LIABILITY

     

    THE
      AGENT
      AND THE LENDERS SHALL NOT HAVE ANY LIABILITY TO ANY GUARANTOR (WHETHER SOUNDING
      IN TORT, CONTRACT, OR OTHERWISE) FOR LOSSES SUFFERED BY ANY GUARANTOR IN
      CONNECTION WITH, ARISING OUT OF, OR IN ANY WAY RELATED TO THE TRANSACTIONS
      OR
      RELATIONSHIPS CONTEMPLATED BY THIS AGREEMENT, OR ANY ACT, OMISSION OR EVENT
      OCCURRING IN CONNECTION THEREWITH, UNLESS IT IS DETERMINED BY A FINAL AND
      NONAPPEALABLE JUDGMENT OR COURT ORDER BINDING ON THE AGENT OR LENDER, AS
      APPLICABLE, THAT THE LOSSES WERE THE RESULT OF ACTS OR OMISSIONS CONSTITUTING
      GROSS NEGLIGENCE OR WILLFUL MISCONDUCT.

     

    6.18  DELAYS;
      PARTIAL EXERCISE OF REMEDIES

     

    No
      delay
      or omission of the Agent to exercise any right or remedy hereunder, whether
      before or after the happening of any Event of Default, shall impair any such
      right or shall operate as a waiver thereof or as a waiver of any such Event
      of
      Default. No single or partial exercise by the Agent of any right or remedy
      shall
      preclude any other or further exercise thereof, or preclude any other right
      or
      remedy.

     

    6.19  JURY
      TRIAL

     

    GUARANTOR
      AND THE AGENT HEREBY IRREVOCABLY WAIVES ALL RIGHT TO TRIAL BY JURY IN ANY
      ACTION, PROCEEDING OR COUNTERCLAIM (WHETHER BASED ON CONTRACT, TORT OR
      OTHERWISE) ARISING OUT OF OR RELATING TO ANY TRANSACTION DOCUMENT OR THE ACTIONS
      OF ANY PARTY IN THE NEGOTIATION, ADMINISTRATION, PERFORMANCE OR ENFORCEMENT
      THEREOF.

     

    
      
        
        

      

      
        17

        
          

        

      

      
        
        

      

    

     

    IN
      WITNESS WHEREOF,
      Guarantor has caused this Guarantor General Security Agreement to be duly
      executed and delivered as of the date first written above.

     

    
      	 	 	 
	 	ACURA
              PHARMACEUTICAL TECHNOLOGIES,
              INC.
	 
 	 
 	 
 
	 	By:  	/s/ Andrew
              D.
              Reddick 
	 	
              
Name:
              Andrew D. Reddick
	 	Title:
              President and Chief Executive Officer


    

    


    By
      its
      acceptance hereof, as of the day and year first above written, the Agent agrees
      to be bound by the provisions hereof applicable to it.

    


    
      
        	 	 	 
	 	GALEN
                PARTNERS III, L.P. 
	 	By:  	Claudius,
                L.L.C,
                General Partner
	 	610 Fifth Avenue, 5th
                Fl.
	 	New
                York, New York 10019


      

      
        	 	 	 
	 	 
	 	By:  	/s/ Bruce
                F.
                Wesson
	 	
                
Name:
                Bruce F. Wesson, its General Partner
	 	 


      



    
      
        
        

      

      
        18

        
          

        

      

      
        
        

      

       

    

    SCHEDULE
      A

    


    Section
      3.3

    


     APT

    


    16235
      State Road 17, Culver, Indiana 46511.

     

     

    
      
        
        

      

      19