S-Metolachlor Dietary Exposure and Risk Assessment DP # 0425 169 

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

MEMORANDUM 

Date: 05/7/2015 

OFFICE OF CHEMICAL SAFETY AND 

POLLUTION PREVENTION 

SUBJECT: S-metolachlor - Acute and Chronic Aggregate Dietary (Food and Drinking 

Water) Exposure and Risk Assessment for Establishment of Tolerances for New 

Uses on Lettuce, Low Growing Berry Subgroup l 3-07G, except Cranberry; 

Vegetable, Cucurbit, Group 9; Sunflower subgroup 208 ; Vegetable, Fruiting, 

Group 8- l O; except Tabasco Pepper. . 

PC Code: I 08800 

Decision No.: 488023 

Petition No.: 4E8248 

Risk Assessment Type: Dietary 

TXR No.: NA 

MRID No.: NA 

From: Thurston G. Morton, Chemist 

Risk Assessment Branch IV / Healt 

DP Barcode: 0425169 

Registration No.: I 00-816 

· Regulatory Action: Section 3 Registration 

Case No.: 000 I 

CAS No.: 87392-12-9 

40 CF : § 180.368 

f ects Division -~ (RABIV/HED; 7509P) 

T h rough: Douglas Dotson, Ph.D., Senior Chemist /). ~~ 

Nancy 

Dietary 

Dodd

Exposure 

, Chemi

Science 

st ~ 

Advistfr'y Council 

~ 

(DESAC) 

And 

Elissa Reaves PhD., Branch Chief 

RAB IV /HED (7509P) 

To: Barbara Madden/Sidney Jackson, PM#5 

Minor Use & Emergency Response Branch 

Registration Division (7505P) 

Page I of24 
S-Metolachlor Dietary Exposure and Risk Assessment DP # 0425169 

Executive Summa ry 

Acute and chronic aggregate dietary [food and drinking water] exposure and risk assessments 

were conducted using the Dietary Exposure Evaluation Model software with the Food 

Commodity Intake Database (DEEM-FCID) Version 3.16. This software uses 2003-2008 food 

consumption data from the U.S. Department of Agriculture's (USDA's) National Health and 

Nutrition Examination Survey, What We Eat in America (NHANES/WWETA). The analyses 

were conducted in support of a human-health risk assessment for the proposed Section 3 of Smetolachlor on lettuce, low growing berry subgroup l 3-07G, except cranberry; vegetable, 

cucurbit, group 9; vegetable, fruiting, group 8- 1 O; except tabasco pepper and okra, and sunflower 

subgroup 208. 

This memorandum was reviewed by two peer reviewers of the DESAC per DESAC SOP 20 12. l. 

/\cute Dietary Exposure Results and Characterization 

/\.conservative acute dietary exposure analysis was performed for the general U.S. population 

and various population subgroups. Tolerance-level residues and I 00 percent crop treated 

assumptions were used. DEEM default processing factors were used to modify the tolerance 

values. The acute analysis incorporated the l in 10 year peak groundwater estimate from 

application of S-metolachlor on cotton. This assessment concludes that, for all supported 

commodities, the acute dietary exposure estimates are below HED's level of concern. The 95111 

percentile acute dietary exposure estimates for the general U.S. population and the highest 

exposed population subgroup, all infants < I year old, are 2.1 % and 6. 1 %, respectively, of the 

acute population adjusted dose (a.PAD). 

Chronic Dietary Exposure Results and Characterization 

A conservative chronic dietary exposure analysis was performed for the general U.S. population 

and various population subgroups. Tolerance-level residues and 100 percent crop treated 

assumptions were used. DEEM default processing factors were used to modify the tolerance 

values. The chronic analysis incorporated the I 0 year average surface drinking water estimate 

from application of S-metolachlor to lettuce. The chronic dietary exposure estimate for the 

general U.S. population and the highest exposed population subgroup, children 1-2 years old, is 

6.8% and 3.1 % of the chronic population adjusted dose (cPAD), respectively. 

l. Introduction 

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose that I lED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the population-adjusted dose (PAD). The PAD is equivalent to the 

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S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

Page 3 of 24

point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety 

factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% of the PAD. References that discuss the acute and chronic risk assessments in 

more detail are available on the EPA/pesticides web site: “Available Information on Assessing 

Exposure from Pesticides, A User’s Guide,” 21-JUN-2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (20-AUG1999).

The most recent dietary risk assessment for S-metolachlor was conducted by R. Duncan

(D396451, 1/3/12) for the Section 3 use on cilantro and garden beet leaves.

II. Residue Information

Metolachlor (PC Code 108801) is a racemic herbicide that consists of 50% each of the Renantiomer and the S-enantiomer. S-metolachlor products are an isomer enriched formula 

comprised of 88% S-isomer and 12% R-isomer. The residues of concern for S-metolachlor are 

the same as those for metolachlor (D226780, L. Kutney, 11/12/96). The Metabolism Assessment 

Review Committee (MARC, 8/14/001) determined that the residues of concern for plant and 

livestock commodities are metolachlor and its metabolites, determined as the derivatives 2-[(2-

ethyl-6-methylphenyl)amino]-1-propanol (CGA-37913) and 4-(2-ethyl-6-methylphenyl)-2-

hydroxy-5-methyl-3-morpholinone (CGA-49751). Metabolites of metolachlor are assumed to be 

toxicologically equivalent to parent metolachlor. Permanent tolerances are established in 40 

CFR §180.368(a)(2) for S-metolachlor, including its metabolites and degradates in/on a variety 

of crop commodities, at levels ranging from 0.02 in/on meat and dairy products to 20 ppm in/on 

peanut hay. Compliance with the tolerance levels is to be determined by measuring Smetolachlor, its R-enantiomer, and the two metabolites CGA-37913 and CGA-49751. In cases 

where separate tolerance listings occur for both metolachlor and S-metolachlor on the same 

commodity, the higher value of the two is used in the analyses. Residues used in the acute and 

chronic dietary analyses are provided in Tables 1, 2, 3 and 4.

The recommended tolerances for the proposed commodities are as follows: 1.5 ppm on lettuce, 

0.50 ppm on vegetable, cucurbit group 9, 0.10 ppm on vegetable, fruiting group 8-10, except 

tabasco pepper and okra, 0.40 ppm on low growing berry subgroup 13-07G except cranberry, 

and 0.50 ppm on sunflower subgroup 20B (S. Hummel, D420046, 10/27/14).
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Table 1. Metolachlor Tolerances

Commodity Tolerance (ppm)

Cattle, fat; Cattle, meat 0.02

Cattle, kidney 0.20

Cattle, liver 0.05

Cattle, meat byproducts, except kidney and liver 0.04

Corn, field, grain 0.10

Corn, pop, grain 0.10

Corn, sweet, kernel plus cob with husks removed 0.10

Cotton, undelinted seed 0.10

Dillweed 0.50

Egg 0.02

Goat, fat; Goat, meat 0.02

Goat, kidney 0.20

Goat, liver 0.05

Goat, meat byproducts, except kidney and liver 0.04

Horse, fat; Horse, meat 0.02

Horse, kidney 0.20

Horse, liver 0.05

Horse, meat byproducts, except kidney and liver 0.04

Milk 0.02

Nut, tree, group 14 0.10

Okra 0.50

Peanut 0.20

Pepper, nonbell (Sec 18) 0.50

Potato 0.20

Poultry, fat; Poultry, meat 0.02

Poultry, meat byproducts 0.05

Sheep, fat; Sheep, meat 0.02

Sheep, kidney 0.20

Sheep, liver 0.05

Sheep, meat byproducts, except kidney and liver 0.04

Sorghum, grain, grain 0.30

Soybean, seed (superseded by legume tolerance of 0.3 ppm) 0.20

Tomato 0.10

Vegetable, legume, group 6 0.30

Table 2. S-metolachlor Tolerances 

Commodity Tolerance (ppm)

Asparagus 0.10

Beet, garden, leaves 1.8

Beet, sugar, molasses 2.0

Beet, sugar, roots 0.50

Beet, sugar, tops 15

Brassica, head and stem, subgroup 5A 0.60

Brassica, leafy greens, subgroup 5B 1.8

Bushberry subgroup 13-07B 0.15

Caneberry, subgroup 13-07A 0.10

Low grow berry subgroup 13-07G (except cranberry) 0.40
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Table 2. S-metolachlor Tolerances 

Commodity Tolerance (ppm)

Carrot, roots 0.40

Cattle, fat; Cattle, meat 0.02

Cattle, kidney 0.20

Cattle, liver 0.05

Cattle, meat byproducts, except kidney and liver 0.04

Cilantro, leaves 8.0

Coriander, seed 0.13

Corn, field, grain 0.10

Corn, pop, grain 0.10

Corn, sweet, kernel plus cob with husks removed 0.10

Cotton, undelinted seed 0.10

Egg 0.02

Goat, fat; Goat, meat 0.02

Goat, kidney 0.20

Goat, liver 0.05

Goat, meat byproducts, except kidney and liver 0.04

Horse, fat; Horse, meat 0.02

Horse, kidney 0.20

Horse, liver 0.05

Horse, meat byproducts, except kidney and liver 0.04

Leaf petioles, subgroup 4B 0.10

Milk 0.02

Okra 0.50

Onion, bulb, subgroup 3-07A 0.10

Onion, green, subgroup 3-07B 2.0

Peanut 0.20

Pepper, tabasco (regional registration) 0.50

Poultry, fat; Poultry, meat 0.02

Poultry, meat byproducts 0.05

Safflower, seed 0.10

Sesame, seed 0.13

Sheep, fat; Sheep, meat 0.02

Sheep, kidney 0.20

Sheep, liver 0.05

Sheep, meat byproducts, except kidney and liver 0.04

Sorghum, grain, grain 0.30

Soybean, seed(superseded by legume tolerance of 0.3 ppm) 0.20

Spinach 0.50

Sunflower, seed 0.50

Tomato, paste 0.30

Vegetable, fruiting, group 8, except tabasco pepper 0.10

Vegetable, legume, group 6 0.30

Vegetable, root, except sugar beet, subgroup 1B except carrot 0.30

Vegetable, tuberous and corm, subgroup 1C 0.20
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Table 3. Metolachlor Inadvertent Tolerances

Commodities Tolerance (ppm)

Barley, grain 0.10

Buckwheat, grain 0.10

Millet, grain 0.10

Oat, grain 0.10

Rice, grain 0.10

Rye, grain 0.10

Wheat, grain 0.10

Table 4. S-metolachlor Inadvertent Tolerances

Commodity Tolerance (ppm)

Barley, grain 0.10

Buckwheat, grain 0.10

Millet, grain 0.10

Oat, grain 0.10

Rice, grain 0.10

Rye, grain 0.10

Wheat, grain 0.10

Residues in Fish: In 2008, 2009, and 2010 the USDA Pesticide Data Program (PDP) analyzed 

catfish samples for metolachlor. There was only 1 detected residue of metolachlor. 

III. Percent Crop Treated Information

The acute and chronic dietary exposure analyses assumed 100% crop treated (CT).

IV. Drinking Water Data

The drinking water residues used in the dietary risk assessment were provided by the 

Environmental Fate and Effects Division (EFED) in the following memorandum: “Tier II 

Drinking Water Assessment for the Proposed S-Metolachlor Use on Lettuce (Head and Leaf), 

Low-Growing Berry Subgroup 13-07G (excluding Cranberry), Cucurbit Vegetable Group 9, 

Sunflower Subgroup 20B and Fruiting Vegetable Group 8-10. ” (D420047, C. Koper, 12/16/14) 

and incorporated directly into this dietary assessment. Water residues were incorporated in the 

DEEM-FCID into the food categories “water, direct, all sources” and “water, indirect, all 

sources.” 

Following the recent recommendation of the Residues of Concern Knowledgebase 

Subcommittee (D424250), parent metolachlor, CGA-51202 (metolachlor-OA), CGA-40172, and 

CGA-50720 will be assessed together in the drinking water assessment using a total toxic 

residues (TTR; USEPA 2009a) approach where half-lives were recalculated (PestDF; USEPA, 

2009b) to collectively account for the parent and the combined residues of concern. These 

values will be utilized in surface and ground water modeling to generate aquatic exposure 

estimates.
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Recommended EDWCs of S-metolachlor in surface water and ground water are reported in

Table 5. The EDWC used in the acute assessment is 1.060 ppm. The EDWC used in the chronic 

assessment is 0.0437 ppm.

The acute EDWC is a ground water value generated using the Pesticide Root Zone Model –

Ground Water (PRZM-GW) based on a 30 year simulation of 2 foliar applications of 2.0 lbs 

a.i./A for a maximum annual rate of 4.0 lbs a.i/A for corn/cotton.

The chronic EDWC is a surface water value generated using the Surface Water Concentration 

Calculator (SWCC) model using aerial application with a percent crop treated (PCA) factor of 

0.91, based on the current proposed use on lettuce (2 apps x 0.95 lbs a.i./A x 2 seasons).

Table 5. Recommended EDWCs for S-Metolachlor Use on Various Crops

Drinking Water 

Source Crop Scenario

1-in-10 year 

acute 

(μg/L)

1-in-10 year 

chronic

(μg/L)

30- year average 

cancer chronic 

(μg/L)

Surface Water MS Corn 1(aerial) 371 -- --

CA Lettuce 2(aerial) -- 43.70* 21.80

Ground Water NC Cotton 3 (aerial) 1060* NA --

WI Corn 3 (aerial) -- NA 978

1 EDWC calculated from the maximum rate (2 apps x 2.0 lbs a.i./A) registered on corn and cotton generated using

SWCC model (aerial application; TTR approach) with a PCA factor of 0.91. 

2 Current proposed use on lettuce (2 apps x 0.95 lbs a.i./A x 2 seasons).

3 Highest EDWCs generated using PRZM-GW model based on a 30 year simulation of 2 foliar applications of 

 2.0 lbs a.i./A for a maximum annual rate of 4.0 lbs a.i/A for corn/cotton (Metolachlor RED; D185152, 172022).

*Bolded concentrations were used in the acute and chronic dietary exposure analyses.

V. DEEM-FCID Program and Consumption Information

S-metolachlor acute and chronic dietary exposure assessments were conducted using the DEEMFCID, Version 3.16, which incorporates 2003-2008 consumption data from USDA’s 

NHANES/WWEIA. The data are based on the reported consumption of more than 20,000 

individuals over two non-consecutive survey days. Foods “as consumed” (e.g., apple pie) are 

linked to EPA-defined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; 

or wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files 

developed jointly by USDA/ARS and EPA. For chronic exposure assessment, consumption data 

are averaged for the entire U.S. population and within population subgroups. However, for acute 

exposure assessment, consumption data are retained as individual consumption events. Based on 

analysis of the 2003-2008 WWEIA consumption data, which took into account dietary patterns 

and survey respondents, HED concluded that it is most appropriate to report risk for the 

following population subgroups: the general U.S. population, all infants (<1 year old), children 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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1-2, children 3-5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50-99

years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 

The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on an 

individual-by-individual basis. The reported consumption amounts of each food item can be 

multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a 

deterministic exposure assessment, or “matched” in multiple random pairings with residue values 

and then summed in a probabilistic assessment. The resulting distribution of exposures is 

expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating 

relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant 

commodities as well as those who did not) basis. In accordance with HED policy, per capita 

exposure and risk are reported for analyses performed at all levels of refinement. However, for 

deterministic assessments, any significant differences in user vs. per capita exposure and risk are 

specifically identified and noted in the risk assessment.

VI. Toxicological Information

HED evaluated the toxicology database for S-metolachlor and selected the following doses and 

endpoints for acute and chronic dietary and drinking water risk assessments. 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Table 6. Summary of Toxicological Endpoints for S-metolachlor for Use in Dietary Human Health Risk 

Assessments

Exposure

Scenario

Point of 

Departure

Uncertainty/FQPA 

Safety Factors

RfD, PAD, 

LOC for Risk 

Assessment

Study and Toxicological Effects

Acute 

Dietary

(general 

population)

NOAEL = 

300 

mg/kg/day

UFA= 10x

UFH=10x

FQPA SF= 1x

Acute RfD = 

3.0 mg/kg/day

aPAD = 3.0 

mg/kg/day

Developmental Toxicity Study - Rat 

LOAEL = 1000 mg/kg/day based on 

increased incidence of death, clinical signs 

(clonic and/or tonic convulsions, excessive 

salivation, urine-stained abdominal fur and/or 

excessive lacrimation) and decreased body 

weight gain. 

Chronic 

Dietary 

(all 

populations)

NOAEL = 

9.7

mg/kg/day

UFA= 10x

UFH=10x

FQPA SF= 1x

Chronic RfD = 

0.097

mg/kg/day

cPAD = 

0.097mg/kg/day

Chronic Toxicity - Dog;

LOAEL = 33 mg/kg/day based decreased 

body weight gain in females 

Cancer 

(all routes)

Metolachlor has been classified as a Group C carcinogen with risk quantitated using a non-linear 

(Margin of Exposure) approach. 

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose-response data and used to mark the beginning 

of extrapolation to determine risk associated with lower environmentally relevant human exposures. 

NOAEL = no observed adverse effect level. 

LOAEL = lowest observed adverse effect level. 

UF = uncertainty factor. UFA = extrapolation from animal to human (interspecies). UFH = potential variation in sensitivity among members of 

the human population (intraspecies). 

FQPA SF = FQPA Safety Factor. 

PAD = population adjusted dose (a = acute, c = chronic). 

RfD = reference dose. 

VII. Results/Discussion 

As stated above, for acute and chronic assessments, HED is concerned when dietary risk exceeds 

100% of the PAD. The DEEM-FCIDTM analyses estimate the dietary exposure of the U.S. 

population and various population subgroups. The results reported in Table 7 below are for the 

general U.S. Population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 

13-19, females 13-49, adults 20-49, and adults 50-99 years old.
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169 

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Table 7 Summary of Dietary Food and Drinking Water Exposure and Risk for 

S-metolachlor and Metolachlor.

Population Subgroup

Acute Dietary

(95th Percentile) Chronic Dietary

Dietary 

Exposure 

(mg/kg/day)

% aPAD*

Dietary 

Exposure

(mg/kg/day)

% cPAD*

General U.S. Population 0.061369 2.1 0.003008 3.1

All Infants (<1 year old) 0.184165 6.1 0.005652 5.8

Children 1-2 years old 0.096061 3.2 0.006557 6.8

Children 3-5 years old 0.077899 2.6 0.005513 5.7

Children 6-12 years old 0.059378 2.0 0.003690 3.8

Youth 13-19 years old 0.049953 1.7 0.002407 2.5

Adults 20-49 years old 0.059238 2.0 0.002687 2.8

Adults 50-99 years old 0.053503 1.8 0.002644 2.7

Females 13-49 years old 0.059990 2.0 0.002687 2.8

*The subpopulation(s) with the highest risk estimates are bolded.

VIII. Characterization of Inputs/Outputs

The acute and chronic analyses assumed tolerance-level residues, 100% CT, and DEEM default 

processing factors. Therefore, these analyses are considered conservative. While they could be 

significantly refined, further refinement is not warranted as estimated risks are not of concern. 

IX. Conclusions

Based on analyses of estimated dietary risks for the general U.S. population and various 

population subgroups, the acute and chronic dietary exposure estimates for S-metolachlor are 

significantly below HED’s level of concern for all supported commodities. The 95th percentile 

acute dietary exposure estimate for the highest exposed population subgroup, all infants < 1 year 

old is 6.1% of the aPAD. The chronic dietary exposure estimate for the highest exposed 

population subgroup, children 1-2 years old is 6.8% of the cPAD.

X. List of Attachments

1. Acute DEEM-FCID Residue Input File.

2. Results of Acute DEEM-FCID Dietary Exposure Analysis.

3. Chronic DEEM-FCID Residue Input File.

4. Results of Chronic DEEM-FCID Dietary Exposure Analysis.
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

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Attachment 1 Acute DEEM-FCID Residue Input File

Filename: C:\Users\tmorton\Documents\My Files\DEEM Files\108800 s-Metolachlor\108800 Acute Food 

plus Water.r08

Chemical: s-Metolachlor and Metolachlor

RfD(Chronic): .097 mg/kg bw/day NOEL(Chronic): 9.7 mg/kg bw/day

RfD(Acute): 3 mg/kg bw/day NOEL(Acute): 300 mg/kg bw/day

Date created/last modified: 01-22-2015/09:35:41 Program ver. 3.16, 03-08-d

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

0101050000 1AB Beet, garden, roots 0.300000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.300000 1.000 1.000 

0101052000 1A Beet, sugar 0.500000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.500000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 2.000000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 2.000000 1.000 1.000 

0101067000 1AB Burdock 0.300000 1.000 1.000 

0101078000 1AB Carrot 0.400000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.400000 1.000 1.000 

0101079000 1AB Carrot, juice 0.400000 1.000 1.000 

0101084000 1AB Celeriac 0.300000 1.000 1.000 

0101100000 1AB Chicory, roots 0.300000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.300000 1.000 1.000 

0101190000 1AB Horseradish 0.300000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.300000 1.000 1.000 

0101251000 1AB Parsnip 0.300000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.300000 1.000 1.000 

0101314000 1AB Radish, roots 0.300000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.300000 1.000 1.000 

0101327000 1AB Rutabaga 0.300000 1.000 1.000 

0101331000 1AB Salsify, roots 0.300000 1.000 1.000 

0101388000 1AB Turnip, roots 0.300000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.200000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.200000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.200000 1.000 1.000 

0103082000 1CD Cassava 0.200000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.200000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.200000 1.000 1.000 

0103166000 1CD Ginger 0.200000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.200000 1.000 1.000 

0103167000 1CD Ginger, dried 0.200000 1.000 1.000 

0103296000 1C Potato, chips 0.200000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.200000 6.500 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.200000 6.500 1.000 

0103298000 1C Potato, flour 0.200000 6.500 1.000 

0103298001 1C Potato, flour-babyfood 0.200000 6.500 1.000 

0103299000 1C Potato, tuber, w/peel 0.200000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.200000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.200000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.200000 1.000 1.000 

0103366000 1CD Sweet potato 0.200000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.200000 1.000 1.000 

0103371000 1CD Tanier, corm 0.200000 1.000 1.000 

0103387000 1CD Turmeric 0.200000 1.000 1.000 

0103406000 1CD Yam, true 0.200000 1.000 1.000 

0103407000 1CD Yam bean 0.200000 1.000 1.000 

0200051000 2 Beet, garden, tops 1.800000 1.000 1.000 

0301165000 3A Garlic, bulb 0.100000 1.000 1.000 

0301165001 3A Garlic, bulb-babyfood 0.100000 1.000 1.000 

0301237000 3A Onion, bulb 0.100000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.100000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.100000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.100000 9.000 1.000 

0301338000 3A Shallot, bulb 0.100000 1.000 1.000 

0302103000 3B Chive, fresh leaves 2.000000 1.000 1.000 

0302198000 3B Leek 2.000000 1.000 1.000 

0302239000 3B Onion, green 2.000000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 2.000000 1.000 1.000 
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0401204000 4A Lettuce, head 1.500000 1.000 1.000 

0401205000 4A Lettuce, leaf 1.500000 1.000 1.000 

0401355000 4A Spinach 0.500000 1.000 1.000 

0401355001 4A Spinach-babyfood 0.500000 1.000 1.000 

0402076000 4B Cardoon 0.100000 1.000 1.000 

0402085000 4B Celery 0.100000 1.000 1.000 

0402085001 4B Celery-babyfood 0.100000 1.000 1.000 

0402086000 4B Celery, juice 0.100000 1.000 1.000 

0402087000 4B Celtuce 0.100000 1.000 1.000 

0402152000 4B Fennel, Florence 0.100000 1.000 1.000 

0402322000 4B Rhubarb 0.100000 1.000 1.000 

0402367000 4B Swiss chard 0.100000 1.000 1.000 

0501061000 5A Broccoli 0.600000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.600000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.600000 1.000 1.000 

0501064000 5A Brussels sprouts 0.600000 1.000 1.000 

0501069000 5A Cabbage 0.600000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.600000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.600000 1.000 1.000 

0501083000 5A Cauliflower 0.600000 1.000 1.000 

0501196000 5A Kohlrabi 0.600000 1.000 1.000 

0502063000 5B Broccoli raab 1.800000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 1.800000 1.000 1.000 

0502117000 5B Collards 1.800000 1.000 1.000 

0502194000 5B Kale 1.800000 1.000 1.000 

0502229000 5B Mustard greens 1.800000 1.000 1.000 

0502318000 5B Rape greens 1.800000 1.000 1.000 

0502389000 5B Turnip, greens 1.800000 1.000 1.000 

0600347000 6 Soybean, seed 0.300000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.300000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.300000 1.000 1.000 

0600350000 6 Soybean, oil 0.300000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.300000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.300000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 0.300000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.300000 1.000 1.000 

0601349500 6AB Soybean, vegetable 0.300000 1.000 1.000 

0602031000 6B Bean, broad, succulent 0.300000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.300000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.300000 1.000 1.000 

0602255000 6B Pea, succulent 0.300000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.300000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.300000 1.000 1.000 

0603030000 6C Bean, black, seed 0.300000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.300000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.300000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.300000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.300000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.300000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.300000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.300000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.300000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.300000 1.000 1.000 

0603098000 6C Chickpea, seed 0.300000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.300000 1.000 1.000 

0603099000 6C Chickpea, flour 0.300000 1.000 1.000 

0603182000 6C Guar, seed 0.300000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.300000 1.000 1.000 

0603203000 6C Lentil, seed 0.300000 1.000 1.000 

0603256000 6C Pea, dry 0.300000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.300000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.300000 1.000 1.000 

0603348000 6C Soybean, flour 0.300000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.300000 1.000 1.000 

0801374000 8A Tomatillo 0.100000 1.000 1.000 

0801375000 8A Tomato 0.100000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.100000 1.000 1.000 

0801376000 8A Tomato, paste 0.300000 1.000 1.000 

0801376001 8A Tomato, paste-babyfood 0.300000 1.000 1.000 

0801377000 8A Tomato, puree 0.100000 1.000 1.000 

0801377001 8A Tomato, puree-babyfood 0.100000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 13 of 24

0801378000 8A Tomato, dried 0.100000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.100000 14.300 1.000 

0801379000 8A Tomato, juice 0.100000 1.500 1.000 

0801380000 8A Tomato, Tree 0.100000 1.000 1.000 

0802148000 8BC Eggplant 0.100000 1.000 1.000 

0802234000 8BC Okra 0.500000 1.000 1.000 

0802270000 8B Pepper, bell 0.100000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.100000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.100000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.100000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.500000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.500000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.500000 1.000 1.000 

0901075000 9A Cantaloupe 0.500000 1.000 1.000 

0901187000 9A Honeydew melon 0.500000 1.000 1.000 

0901399000 9A Watermelon 0.500000 1.000 1.000 

0901400000 9A Watermelon, juice 0.500000 1.000 1.000 

0902021000 9B Balsam pear 0.500000 1.000 1.000 

0902088000 9B Chayote, fruit 0.500000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.500000 1.000 1.000 

0902135000 9B Cucumber 0.500000 1.000 1.000 

0902308000 9B Pumpkin 0.500000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.500000 1.000 1.000 

0902356000 9B Squash, summer 0.500000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.500000 1.000 1.000 

0902357000 9B Squash, winter 0.500000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.500000 1.000 1.000 

1301055000 13A Blackberry 0.100000 1.000 1.000 

1301056000 13A Blackberry, juice 0.100000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 0.100000 1.000 1.000 

1301058000 13A Boysenberry 0.100000 1.000 1.000 

1301208000 13A Loganberry 0.100000 1.000 1.000 

1301320000 13A Raspberry 0.100000 1.000 1.000 

1301320001 13A Raspberry-babyfood 0.100000 1.000 1.000 

1301321000 13A Raspberry, juice 0.100000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 0.100000 1.000 1.000 

1302057000 13B Blueberry 0.400000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.400000 1.000 1.000 

1302136000 13B Currant 0.150000 1.000 1.000 

1302137000 13B Currant, dried 0.150000 1.000 1.000 

1302149000 13B Elderberry 0.150000 1.000 1.000 

1302174000 13B Gooseberry 0.150000 1.000 1.000 

1302191000 13B Huckleberry 0.150000 1.000 1.000 

1307359000 13G Strawberry 0.400000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.400000 1.000 1.000 

1307360000 13G Strawberry, juice 0.400000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.400000 1.000 1.000 

1400003000 14 Almond 0.100000 1.000 1.000 

1400003001 14 Almond-babyfood 0.100000 1.000 1.000 

1400004000 14 Almond, oil 0.100000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.100000 1.000 1.000 

1400059000 14 Brazil nut 0.100000 1.000 1.000 

1400068000 14 Butternut 0.100000 1.000 1.000 

1400081000 14 Cashew 0.100000 1.000 1.000 

1400092000 14 Chestnut 0.100000 1.000 1.000 

1400155000 14 Hazelnut 0.100000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.100000 1.000 1.000 

1400185000 14 Hickory nut 0.100000 1.000 1.000 

1400213000 14 Macadamia nut 0.100000 1.000 1.000 

1400269000 14 Pecan 0.100000 1.000 1.000 

1400278000 14 Pine nut 0.100000 1.000 1.000 

1400282000 14 Pistachio 0.100000 1.000 1.000 

1400391000 14 Walnut 0.100000 1.000 1.000 

1500025000 15 Barley, pearled barley 0.100000 1.000 1.000 

1500025001 15 Barley, pearled barley-babyfood 0.100000 1.000 1.000 

1500026000 15 Barley, flour 0.100000 1.000 1.000 

1500026001 15 Barley, flour-babyfood 0.100000 1.000 1.000 

1500027000 15 Barley, bran 0.100000 1.000 1.000 

1500065000 15 Buckwheat 0.100000 1.000 1.000 

1500066000 15 Buckwheat, flour 0.100000 1.000 1.000 

1500120000 15 Corn, field, flour 0.100000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 14 of 24

1500120001 15 Corn, field, flour-babyfood 0.100000 1.000 1.000 

1500121000 15 Corn, field, meal 0.100000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.100000 1.000 1.000 

1500122000 15 Corn, field, bran 0.100000 1.000 1.000 

1500123000 15 Corn, field, starch 0.100000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.100000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.100000 1.000 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.100000 1.000 1.000 

1500125000 15 Corn, field, oil 0.100000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.100000 1.000 1.000 

1500126000 15 Corn, pop 0.100000 1.000 1.000 

1500127000 15 Corn, sweet 0.100000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.100000 1.000 1.000 

1500226000 15 Millet, grain 0.100000 1.000 1.000 

1500231000 15 Oat, bran 0.100000 1.000 1.000 

1500232000 15 Oat, flour 0.100000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 0.100000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 0.100000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 0.100000 1.000 1.000 

1500323000 15 Rice, white 0.100000 1.000 1.000 

1500323001 15 Rice, white-babyfood 0.100000 1.000 1.000 

1500324000 15 Rice, brown 0.100000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 0.100000 1.000 1.000 

1500325000 15 Rice, flour 0.100000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 0.100000 1.000 1.000 

1500326000 15 Rice, bran 0.100000 1.000 1.000 

1500326001 15 Rice, bran-babyfood 0.100000 1.000 1.000 

1500328000 15 Rye, grain 0.100000 1.000 1.000 

1500329000 15 Rye, flour 0.100000 1.000 1.000 

1500344000 15 Sorghum, grain 0.300000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.300000 1.000 1.000 

1500381000 15 Triticale, flour 0.100000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 0.100000 1.000 1.000 

1500401000 15 Wheat, grain 0.100000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.100000 1.000 1.000 

1500402000 15 Wheat, flour 0.100000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.100000 1.000 1.000 

1500403000 15 Wheat, germ 0.100000 1.000 1.000 

1500404000 15 Wheat, bran 0.100000 1.000 1.000 

1500405000 15 Wild rice 0.100000 1.000 1.000 

1901118000 19A Cilantro, leaves 8.000000 1.000 1.000 

1901118001 19A Cilantro, leaves-babyfood 8.000000 1.000 1.000 

1901144000 19A Dillweed 0.500000 1.000 1.000 

1902119000 19B Coriander, seed 0.130000 1.000 1.000 

1902119001 19B Coriander, seed-babyfood 0.130000 1.000 1.000 

2001336000 20A Sesame, seed 0.130000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.130000 1.000 1.000 

2001337000 20A Sesame, oil 0.130000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.130000 1.000 1.000 

2002330000 20B Safflower, oil 0.500000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.500000 1.000 1.000 

2002364000 20B Sunflower, seed 0.500000 1.000 1.000 

2002365000 20B Sunflower, oil 0.500000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.500000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.100000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.100000 1.000 1.000 

3100044000 31 Beef, meat 0.020000 1.000 1.000 

3100044001 31 Beef, meat-babyfood 0.020000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 

3100046000 31 Beef, meat byproducts 0.040000 1.000 1.000 

3100046001 31 Beef, meat byproducts-babyfood 0.040000 1.000 1.000 

3100047000 31 Beef, fat 0.020000 1.000 1.000 

3100047001 31 Beef, fat-babyfood 0.020000 1.000 1.000 

3100048000 31 Beef, kidney 0.200000 1.000 1.000 

3100049000 31 Beef, liver 0.050000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.050000 1.000 1.000 

3200169000 32 Goat, meat 0.020000 1.000 1.000 

3200170000 32 Goat, meat byproducts 0.040000 1.000 1.000 

3200171000 32 Goat, fat 0.020000 1.000 1.000 

3200172000 32 Goat, kidney 0.200000 1.000 1.000 

3200173000 32 Goat, liver 0.050000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 15 of 24

3300189000 33 Horse, meat 0.020000 1.000 1.000 

3500339000 35 Sheep, meat 0.020000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.020000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.040000 1.000 1.000 

3500341000 35 Sheep, fat 0.020000 1.000 1.000 

3500341001 35 Sheep, fat-babyfood 0.020000 1.000 1.000 

3500342000 35 Sheep, kidney 0.200000 1.000 1.000 

3500343000 35 Sheep, liver 0.050000 1.000 1.000 

3600222000 36 Milk, fat 0.020000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.020000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.020000 1.000 1.000 

3600224000 36 Milk, water 0.020000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.020000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.020000 1.000 1.000 

3800221000 38 Meat, game 0.020000 1.000 1.000 

3900312000 39 Rabbit, meat 0.020000 1.000 1.000 

4000093000 40 Chicken, meat 0.020000 1.000 1.000 

4000093001 40 Chicken, meat-babyfood 0.020000 1.000 1.000 

4000094000 40 Chicken, liver 0.050000 1.000 1.000 

4000095000 40 Chicken, meat byproducts 0.050000 1.000 1.000 

4000095001 40 Chicken, meat byproducts-babyfoo 0.050000 1.000 1.000 

4000096000 40 Chicken, fat 0.020000 1.000 1.000 

4000096001 40 Chicken, fat-babyfood 0.020000 1.000 1.000 

4000097000 40 Chicken, skin 0.050000 1.000 1.000 

4000097001 40 Chicken, skin-babyfood 0.050000 1.000 1.000 

5000382000 50 Turkey, meat 0.020000 1.000 1.000 

5000382001 50 Turkey, meat-babyfood 0.020000 1.000 1.000 

5000383000 50 Turkey, liver 0.050000 1.000 1.000 

5000383001 50 Turkey, liver-babyfood 0.050000 1.000 1.000 

5000384000 50 Turkey, meat byproducts 0.050000 1.000 1.000 

5000384001 50 Turkey, meat byproducts-babyfood 0.050000 1.000 1.000 

5000385000 50 Turkey, fat 0.020000 1.000 1.000 

5000385001 50 Turkey, fat-babyfood 0.020000 1.000 1.000 

5000386000 50 Turkey, skin 0.050000 1.000 1.000 

5000386001 50 Turkey, skin-babyfood 0.050000 1.000 1.000 

6000301000 60 Poultry, other, meat 0.020000 1.000 1.000 

6000302000 60 Poultry, other, liver 0.050000 1.000 1.000 

6000303000 60 Poultry, other, meat byproducts 0.050000 1.000 1.000 

6000304000 60 Poultry, other, fat 0.020000 1.000 1.000 

6000305000 60 Poultry, other, skin 0.050000 1.000 1.000 

7000145000 70 Egg, whole 0.020000 1.000 1.000 

7000145001 70 Egg, whole-babyfood 0.020000 1.000 1.000 

7000146000 70 Egg, white 0.020000 1.000 1.000 

7000146001 70 Egg, white (solids)-babyfood 0.020000 1.000 1.000 

7000147000 70 Egg, yolk 0.020000 1.000 1.000 

7000147001 70 Egg, yolk-babyfood 0.020000 1.000 1.000 

8601000000 86A Water, direct, all sources 1.060000 1.000 1.000 

8602000000 86B Water, indirect, all sources 1.060000 1.000 1.000 

9500019000 O Asparagus 0.100000 1.000 1.000 

9500263000 O Peanut 0.200000 1.000 1.000 

9500264000 O Peanut, butter 0.200000 1.890 1.000 

9500265000 O Peanut, oil 0.200000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 16 of 24

Attachment 2. Results of Acute DEEM-FCID Dietary Exposure Analysis

Food and Water

US EPA Ver. 3.18, 03-08-d

DEEM-FCID ACUTE Analysis for S-METOLACHLOR AND METOLACHLOR

 NHANES 2003-2008 2-Day

Residue file: 108800 Acute Food plus Water.r08 Adjustment factor #2 NOT used.

Analysis Date: 01-22-2015/10:57:18 Residue file dated: 01-22-2015/10:45:01

NOEL (Acute) = 300.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: ""

===============================================================================

Summary calculations--per capita:

--- 95th Percentile---- --- 99th Percentile---- ---99.9th Percentile----

Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE 

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Total US Population:

 0.061369 2.05 4888 0.098883 3.30 3033 0.184088 6.14 1629 

All Infants:

 0.184165 6.14 1628 0.247593 8.25 1211 0.362877 12.10 826 

Children 1-2:

 0.096061 3.20 3123 0.141084 4.70 2126 0.333970 11.13 898 

Children 3-5:

 0.077899 2.60 3851 0.116785 3.89 2568 0.184547 6.15 1625 

Children 6-12:

 0.059378 1.98 5052 0.092547 3.08 3241 0.142872 4.76 2099 

Youth 13-19:

 0.049953 1.67 6005 0.081490 2.72 3681 0.121875 4.06 2461 

Adults 20-49:

 0.059238 1.97 5064 0.087047 2.90 3446 0.124221 4.14 2415 

Adults 50-99:

 0.053503 1.78 5607 0.079765 2.66 3761 0.122829 4.09 2442 

Female 13-49:

 0.059990 2.00 5000 0.087956 2.93 3410 0.121039 4.03 2478 

Food Only

US EPA Ver. 3.18, 03-08-d

DEEM-FCID ACUTE Analysis for S-METOLACHLOR AND METOLACHLOR

 NHANES 2003-2008 2-Day

Residue file: 108800 Acute Food Only.r08 Adjustment factor #2 NOT used.

Analysis Date: 01-22-2015/10:48:53 Residue file dated: 01-22-2015/10:44:36

NOEL (Acute) = 300.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: ""

===============================================================================

Summary calculations--per capita:

--- 95th Percentile---- --- 99th Percentile---- ---99.9th Percentile----

Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE 

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Total US Population:

 0.005486 0.18 54682 0.009348 0.31 32093 0.017389 0.58 17252 

All Infants:

 0.009009 0.30 33299 0.015185 0.51 19756 0.019855 0.66 15109 

Children 1-2:

 0.012003 0.40 24993 0.021911 0.73 13691 0.030840 1.03 9727 

Children 3-5:

 0.009890 0.33 30332 0.016190 0.54 18529 0.030185 1.01 9938 

Children 6-12:

 0.006844 0.23 43835 0.011201 0.37 26783 0.015203 0.51 19733 

Youth 13-19:

 0.004198 0.14 71468 0.007086 0.24 42339 0.014079 0.47 21308 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 17 of 24

Adults 20-49:

 0.004442 0.15 67539 0.007335 0.24 40901 0.011159 0.37 26884 

Adults 50-99:

 0.004242 0.14 70726 0.006972 0.23 43031 0.010961 0.37 27370 

Female 13-49:

 0.004587 0.15 65397 0.007656 0.26 39185 0.012159 0.41 24673 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 18 of 24

Attachment 3. Chronic DEEM-FCID Residue Input File

Filename: C:\Users\tmorton\Documents\My Files\DEEM Files\108800 s-Metolachlor\108800 Chronic Food 

plus Water.r08

Chemical: s-Metolachlor and Metolachlor

RfD(Chronic): .097 mg/kg bw/day NOEL(Chronic): 9.7 mg/kg bw/day

RfD(Acute): 3 mg/kg bw/day NOEL(Acute): 300 mg/kg bw/day

Date created/last modified: 01-22-2015/09:36:41 Program ver. 3.16, 03-08-d

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

0101050000 1AB Beet, garden, roots 0.300000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.300000 1.000 1.000 

0101052000 1A Beet, sugar 0.500000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.500000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 2.000000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 2.000000 1.000 1.000 

0101067000 1AB Burdock 0.300000 1.000 1.000 

0101078000 1AB Carrot 0.400000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.400000 1.000 1.000 

0101079000 1AB Carrot, juice 0.400000 1.000 1.000 

0101084000 1AB Celeriac 0.300000 1.000 1.000 

0101100000 1AB Chicory, roots 0.300000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.300000 1.000 1.000 

0101190000 1AB Horseradish 0.300000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.300000 1.000 1.000 

0101251000 1AB Parsnip 0.300000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.300000 1.000 1.000 

0101314000 1AB Radish, roots 0.300000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.300000 1.000 1.000 

0101327000 1AB Rutabaga 0.300000 1.000 1.000 

0101331000 1AB Salsify, roots 0.300000 1.000 1.000 

0101388000 1AB Turnip, roots 0.300000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.200000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.200000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.200000 1.000 1.000 

0103082000 1CD Cassava 0.200000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.200000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.200000 1.000 1.000 

0103166000 1CD Ginger 0.200000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.200000 1.000 1.000 

0103167000 1CD Ginger, dried 0.200000 1.000 1.000 

0103296000 1C Potato, chips 0.200000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.200000 6.500 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.200000 6.500 1.000 

0103298000 1C Potato, flour 0.200000 6.500 1.000 

0103298001 1C Potato, flour-babyfood 0.200000 6.500 1.000 

0103299000 1C Potato, tuber, w/peel 0.200000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.200000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.200000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.200000 1.000 1.000 

0103366000 1CD Sweet potato 0.200000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.200000 1.000 1.000 

0103371000 1CD Tanier, corm 0.200000 1.000 1.000 

0103387000 1CD Turmeric 0.200000 1.000 1.000 

0103406000 1CD Yam, true 0.200000 1.000 1.000 

0103407000 1CD Yam bean 0.200000 1.000 1.000 

0200051000 2 Beet, garden, tops 1.800000 1.000 1.000 

0301165000 3A Garlic, bulb 0.100000 1.000 1.000 

0301165001 3A Garlic, bulb-babyfood 0.100000 1.000 1.000 

0301237000 3A Onion, bulb 0.100000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.100000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.100000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.100000 9.000 1.000 

0301338000 3A Shallot, bulb 0.100000 1.000 1.000 

0302103000 3B Chive, fresh leaves 2.000000 1.000 1.000 

0302198000 3B Leek 2.000000 1.000 1.000 

0302239000 3B Onion, green 2.000000 1.000 1.000 

0302338500 3B Shallot, fresh leaves 2.000000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 19 of 24

0401204000 4A Lettuce, head 1.500000 1.000 1.000 

0401205000 4A Lettuce, leaf 1.500000 1.000 1.000 

0401355000 4A Spinach 0.500000 1.000 1.000 

0401355001 4A Spinach-babyfood 0.500000 1.000 1.000 

0402076000 4B Cardoon 0.100000 1.000 1.000 

0402085000 4B Celery 0.100000 1.000 1.000 

0402085001 4B Celery-babyfood 0.100000 1.000 1.000 

0402086000 4B Celery, juice 0.100000 1.000 1.000 

0402087000 4B Celtuce 0.100000 1.000 1.000 

0402152000 4B Fennel, Florence 0.100000 1.000 1.000 

0402322000 4B Rhubarb 0.100000 1.000 1.000 

0402367000 4B Swiss chard 0.100000 1.000 1.000 

0501061000 5A Broccoli 0.600000 1.000 1.000 

0501061001 5A Broccoli-babyfood 0.600000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.600000 1.000 1.000 

0501064000 5A Brussels sprouts 0.600000 1.000 1.000 

0501069000 5A Cabbage 0.600000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.600000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.600000 1.000 1.000 

0501083000 5A Cauliflower 0.600000 1.000 1.000 

0501196000 5A Kohlrabi 0.600000 1.000 1.000 

0502063000 5B Broccoli raab 1.800000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 1.800000 1.000 1.000 

0502117000 5B Collards 1.800000 1.000 1.000 

0502194000 5B Kale 1.800000 1.000 1.000 

0502229000 5B Mustard greens 1.800000 1.000 1.000 

0502318000 5B Rape greens 1.800000 1.000 1.000 

0502389000 5B Turnip, greens 1.800000 1.000 1.000 

0600347000 6 Soybean, seed 0.300000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.300000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.300000 1.000 1.000 

0600350000 6 Soybean, oil 0.300000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.300000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.300000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 0.300000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.300000 1.000 1.000 

0601349500 6AB Soybean, vegetable 0.300000 1.000 1.000 

0602031000 6B Bean, broad, succulent 0.300000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.300000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.300000 1.000 1.000 

0602255000 6B Pea, succulent 0.300000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.300000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.300000 1.000 1.000 

0603030000 6C Bean, black, seed 0.300000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.300000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.300000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.300000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.300000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.300000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.300000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.300000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.300000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.300000 1.000 1.000 

0603098000 6C Chickpea, seed 0.300000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.300000 1.000 1.000 

0603099000 6C Chickpea, flour 0.300000 1.000 1.000 

0603182000 6C Guar, seed 0.300000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.300000 1.000 1.000 

0603203000 6C Lentil, seed 0.300000 1.000 1.000 

0603256000 6C Pea, dry 0.300000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.300000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.300000 1.000 1.000 

0603348000 6C Soybean, flour 0.300000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.300000 1.000 1.000 

0801374000 8A Tomatillo 0.100000 1.000 1.000 

0801375000 8A Tomato 0.100000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.100000 1.000 1.000 

0801376000 8A Tomato, paste 0.300000 1.000 1.000 

0801376001 8A Tomato, paste-babyfood 0.300000 1.000 1.000 

0801377000 8A Tomato, puree 0.100000 1.000 1.000 

0801377001 8A Tomato, puree-babyfood 0.100000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 20 of 24

0801378000 8A Tomato, dried 0.100000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.100000 14.300 1.000 

0801379000 8A Tomato, juice 0.100000 1.500 1.000 

0801380000 8A Tomato, Tree 0.100000 1.000 1.000 

0802148000 8BC Eggplant 0.100000 1.000 1.000 

0802234000 8BC Okra 0.500000 1.000 1.000 

0802270000 8B Pepper, bell 0.100000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.100000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.100000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.100000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.500000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.500000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.500000 1.000 1.000 

0901075000 9A Cantaloupe 0.500000 1.000 1.000 

0901187000 9A Honeydew melon 0.500000 1.000 1.000 

0901399000 9A Watermelon 0.500000 1.000 1.000 

0901400000 9A Watermelon, juice 0.500000 1.000 1.000 

0902021000 9B Balsam pear 0.500000 1.000 1.000 

0902088000 9B Chayote, fruit 0.500000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.500000 1.000 1.000 

0902135000 9B Cucumber 0.500000 1.000 1.000 

0902308000 9B Pumpkin 0.500000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.500000 1.000 1.000 

0902356000 9B Squash, summer 0.500000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.500000 1.000 1.000 

0902357000 9B Squash, winter 0.500000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.500000 1.000 1.000 

1301055000 13A Blackberry 0.100000 1.000 1.000 

1301056000 13A Blackberry, juice 0.100000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 0.100000 1.000 1.000 

1301058000 13A Boysenberry 0.100000 1.000 1.000 

1301208000 13A Loganberry 0.100000 1.000 1.000 

1301320000 13A Raspberry 0.100000 1.000 1.000 

1301320001 13A Raspberry-babyfood 0.100000 1.000 1.000 

1301321000 13A Raspberry, juice 0.100000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 0.100000 1.000 1.000 

1302057000 13B Blueberry 0.400000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.400000 1.000 1.000 

1302136000 13B Currant 0.150000 1.000 1.000 

1302137000 13B Currant, dried 0.150000 1.000 1.000 

1302149000 13B Elderberry 0.150000 1.000 1.000 

1302174000 13B Gooseberry 0.150000 1.000 1.000 

1302191000 13B Huckleberry 0.150000 1.000 1.000 

1307359000 13G Strawberry 0.400000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.400000 1.000 1.000 

1307360000 13G Strawberry, juice 0.400000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.400000 1.000 1.000 

1400003000 14 Almond 0.100000 1.000 1.000 

1400003001 14 Almond-babyfood 0.100000 1.000 1.000 

1400004000 14 Almond, oil 0.100000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.100000 1.000 1.000 

1400059000 14 Brazil nut 0.100000 1.000 1.000 

1400068000 14 Butternut 0.100000 1.000 1.000 

1400081000 14 Cashew 0.100000 1.000 1.000 

1400092000 14 Chestnut 0.100000 1.000 1.000 

1400155000 14 Hazelnut 0.100000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.100000 1.000 1.000 

1400185000 14 Hickory nut 0.100000 1.000 1.000 

1400213000 14 Macadamia nut 0.100000 1.000 1.000 

1400269000 14 Pecan 0.100000 1.000 1.000 

1400278000 14 Pine nut 0.100000 1.000 1.000 

1400282000 14 Pistachio 0.100000 1.000 1.000 

1400391000 14 Walnut 0.100000 1.000 1.000 

1500025000 15 Barley, pearled barley 0.100000 1.000 1.000 

1500025001 15 Barley, pearled barley-babyfood 0.100000 1.000 1.000 

1500026000 15 Barley, flour 0.100000 1.000 1.000 

1500026001 15 Barley, flour-babyfood 0.100000 1.000 1.000 

1500027000 15 Barley, bran 0.100000 1.000 1.000 

1500065000 15 Buckwheat 0.100000 1.000 1.000 

1500066000 15 Buckwheat, flour 0.100000 1.000 1.000 

1500120000 15 Corn, field, flour 0.100000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 21 of 24

1500120001 15 Corn, field, flour-babyfood 0.100000 1.000 1.000 

1500121000 15 Corn, field, meal 0.100000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.100000 1.000 1.000 

1500122000 15 Corn, field, bran 0.100000 1.000 1.000 

1500123000 15 Corn, field, starch 0.100000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.100000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.100000 1.000 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.100000 1.000 1.000 

1500125000 15 Corn, field, oil 0.100000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.100000 1.000 1.000 

1500126000 15 Corn, pop 0.100000 1.000 1.000 

1500127000 15 Corn, sweet 0.100000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.100000 1.000 1.000 

1500226000 15 Millet, grain 0.100000 1.000 1.000 

1500231000 15 Oat, bran 0.100000 1.000 1.000 

1500232000 15 Oat, flour 0.100000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 0.100000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 0.100000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 0.100000 1.000 1.000 

1500323000 15 Rice, white 0.100000 1.000 1.000 

1500323001 15 Rice, white-babyfood 0.100000 1.000 1.000 

1500324000 15 Rice, brown 0.100000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 0.100000 1.000 1.000 

1500325000 15 Rice, flour 0.100000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 0.100000 1.000 1.000 

1500326000 15 Rice, bran 0.100000 1.000 1.000 

1500326001 15 Rice, bran-babyfood 0.100000 1.000 1.000 

1500328000 15 Rye, grain 0.100000 1.000 1.000 

1500329000 15 Rye, flour 0.100000 1.000 1.000 

1500344000 15 Sorghum, grain 0.300000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.300000 1.000 1.000 

1500381000 15 Triticale, flour 0.100000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 0.100000 1.000 1.000 

1500401000 15 Wheat, grain 0.100000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.100000 1.000 1.000 

1500402000 15 Wheat, flour 0.100000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.100000 1.000 1.000 

1500403000 15 Wheat, germ 0.100000 1.000 1.000 

1500404000 15 Wheat, bran 0.100000 1.000 1.000 

1500405000 15 Wild rice 0.100000 1.000 1.000 

1901118000 19A Cilantro, leaves 8.000000 1.000 1.000 

1901118001 19A Cilantro, leaves-babyfood 8.000000 1.000 1.000 

1901144000 19A Dillweed 0.500000 1.000 1.000 

1902119000 19B Coriander, seed 0.130000 1.000 1.000 

1902119001 19B Coriander, seed-babyfood 0.130000 1.000 1.000 

2001336000 20A Sesame, seed 0.130000 1.000 1.000 

2001336001 20A Sesame, seed-babyfood 0.130000 1.000 1.000 

2001337000 20A Sesame, oil 0.130000 1.000 1.000 

2001337001 20A Sesame, oil-babyfood 0.130000 1.000 1.000 

2002330000 20B Safflower, oil 0.500000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.500000 1.000 1.000 

2002364000 20B Sunflower, seed 0.500000 1.000 1.000 

2002365000 20B Sunflower, oil 0.500000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.500000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.100000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.100000 1.000 1.000 

3100044000 31 Beef, meat 0.020000 1.000 1.000 

3100044001 31 Beef, meat-babyfood 0.020000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 

3100046000 31 Beef, meat byproducts 0.040000 1.000 1.000 

3100046001 31 Beef, meat byproducts-babyfood 0.040000 1.000 1.000 

3100047000 31 Beef, fat 0.020000 1.000 1.000 

3100047001 31 Beef, fat-babyfood 0.020000 1.000 1.000 

3100048000 31 Beef, kidney 0.200000 1.000 1.000 

3100049000 31 Beef, liver 0.050000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.050000 1.000 1.000 

3200169000 32 Goat, meat 0.020000 1.000 1.000 

3200170000 32 Goat, meat byproducts 0.040000 1.000 1.000 

3200171000 32 Goat, fat 0.020000 1.000 1.000 

3200172000 32 Goat, kidney 0.200000 1.000 1.000 

3200173000 32 Goat, liver 0.050000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 22 of 24

3300189000 33 Horse, meat 0.020000 1.000 1.000 

3500339000 35 Sheep, meat 0.020000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.020000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.040000 1.000 1.000 

3500341000 35 Sheep, fat 0.020000 1.000 1.000 

3500341001 35 Sheep, fat-babyfood 0.020000 1.000 1.000 

3500342000 35 Sheep, kidney 0.200000 1.000 1.000 

3500343000 35 Sheep, liver 0.050000 1.000 1.000 

3600222000 36 Milk, fat 0.020000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.020000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.020000 1.000 1.000 

3600224000 36 Milk, water 0.020000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.020000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.020000 1.000 1.000 

3800221000 38 Meat, game 0.020000 1.000 1.000 

3900312000 39 Rabbit, meat 0.020000 1.000 1.000 

4000093000 40 Chicken, meat 0.020000 1.000 1.000 

4000093001 40 Chicken, meat-babyfood 0.020000 1.000 1.000 

4000094000 40 Chicken, liver 0.050000 1.000 1.000 

4000095000 40 Chicken, meat byproducts 0.050000 1.000 1.000 

4000095001 40 Chicken, meat byproducts-babyfoo 0.050000 1.000 1.000 

4000096000 40 Chicken, fat 0.020000 1.000 1.000 

4000096001 40 Chicken, fat-babyfood 0.020000 1.000 1.000 

4000097000 40 Chicken, skin 0.050000 1.000 1.000 

4000097001 40 Chicken, skin-babyfood 0.050000 1.000 1.000 

5000382000 50 Turkey, meat 0.020000 1.000 1.000 

5000382001 50 Turkey, meat-babyfood 0.020000 1.000 1.000 

5000383000 50 Turkey, liver 0.050000 1.000 1.000 

5000383001 50 Turkey, liver-babyfood 0.050000 1.000 1.000 

5000384000 50 Turkey, meat byproducts 0.050000 1.000 1.000 

5000384001 50 Turkey, meat byproducts-babyfood 0.050000 1.000 1.000 

5000385000 50 Turkey, fat 0.020000 1.000 1.000 

5000385001 50 Turkey, fat-babyfood 0.020000 1.000 1.000 

5000386000 50 Turkey, skin 0.050000 1.000 1.000 

5000386001 50 Turkey, skin-babyfood 0.050000 1.000 1.000 

6000301000 60 Poultry, other, meat 0.020000 1.000 1.000 

6000302000 60 Poultry, other, liver 0.050000 1.000 1.000 

6000303000 60 Poultry, other, meat byproducts 0.050000 1.000 1.000 

6000304000 60 Poultry, other, fat 0.020000 1.000 1.000 

6000305000 60 Poultry, other, skin 0.050000 1.000 1.000 

7000145000 70 Egg, whole 0.020000 1.000 1.000 

7000145001 70 Egg, whole-babyfood 0.020000 1.000 1.000 

7000146000 70 Egg, white 0.020000 1.000 1.000 

7000146001 70 Egg, white (solids)-babyfood 0.020000 1.000 1.000 

7000147000 70 Egg, yolk 0.020000 1.000 1.000 

7000147001 70 Egg, yolk-babyfood 0.020000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.043700 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.043700 1.000 1.000 

9500019000 O Asparagus 0.100000 1.000 1.000 

9500263000 O Peanut 0.200000 1.000 1.000 

9500264000 O Peanut, butter 0.200000 1.890 1.000 

9500265000 O Peanut, oil 0.200000 1.000 1.000 
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 23 of 24

Attachment 4 Results of Chronic DEEM-FCID Dietary Exposure Analysis

Food and Water

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for S-METOLACHLOR AND METOLACHLOR

 NHANES 2003-2008 2-day

Residue file name: C:\Users\tmorton\Documents\My Files\DEEM Files\108800 s-Metolachlor\108800 

Chronic Food plus Water.r08

 Adjustment factor #2 NOT used.

Analysis Date 01-22-2015/10:47:30 Residue file dated: 01-22-2015/10:46:05

Reference dose (RfD, Chronic) = .097 mg/kg bw/day

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.003008 3.1%

Hispanic 0.002977 3.1%

Non-Hisp-White 0.003039 3.1%

Non-Hisp-Black 0.002660 2.7%

Non-Hisp-Other 0.003509 3.6%

Nursing Infants 0.002830 2.9%

Non-Nursing Infants 0.006912 7.1%

Female 13+ PREG 0.002782 2.9%

Children 1-6 0.005774 6.0%

Children 7-12 0.003487 3.6%

Male 13-19 0.002427 2.5%

Female 13-19/NP 0.002390 2.5%

Male 20+ 0.002566 2.6%

Female 20+/NP 0.002758 2.8%

Seniors 55+ 0.002610 2.7%

All Infants 0.005652 5.8%

Female 13-50 0.002682 2.8%

Children 1-2 0.006557 6.8%

Children 3-5 0.005513 5.7%

Children 6-12 0.003690 3.8%

Youth 13-19 0.002407 2.5%

Adults 20-49 0.002687 2.8%

Adults 50-99 0.002644 2.7%

Female 13-49 0.002687 2.8%

-------------------------------------------------------------------------------
S-Metolachlor Dietary Exposure and Risk Assessment DP # D425169

Page 24 of 24

Food Only

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for S-METOLACHLOR AND METOLACHLOR

 NHANES 2003-2008 2-day

Residue file name: C:\Users\tmorton\Documents\My Files\DEEM Files\108800 s-Metolachlor\108800 

Chronic Food Only.r08

 Adjustment factor #2 NOT used.

Analysis Date 01-22-2015/10:47:02 Residue file dated: 01-22-2015/10:45:46

Reference dose (RfD, Chronic) = .097 mg/kg bw/day

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.002093 2.2%

Hispanic 0.002104 2.2%

Non-Hisp-White 0.002098 2.2%

Non-Hisp-Black 0.001905 2.0%

Non-Hisp-Other 0.002454 2.5%

Nursing Infants 0.002002 2.1%

Non-Nursing Infants 0.003869 4.0%

Female 13+ PREG 0.001921 2.0%

Children 1-6 0.004602 4.7%

Children 7-12 0.002724 2.8%

Male 13-19 0.001798 1.9%

Female 13-19/NP 0.001685 1.7%

Male 20+ 0.001714 1.8%

Female 20+/NP 0.001797 1.9%

Seniors 55+ 0.001725 1.8%

All Infants 0.003292 3.4%

Female 13-50 0.001771 1.8%

Children 1-2 0.005237 5.4%

Children 3-5 0.004401 4.5%

Children 6-12 0.002888 3.0%

Youth 13-19 0.001740 1.8%

Adults 20-49 0.001774 1.8%

Adults 50-99 0.001742 1.8%

Female 13-49 0.001777 1.8%

-------------------------------------------------------------------------------