<PAGE>

                                                                    EXHIBIT 10.1

                              EMPLOYMENT AGREEMENT


THIS EMPLOYMENT AGREEMENT (this "Agreement"), is executed and delivered to be
effective as of January 17, 2006 (the "Effective Date"), by and between
Endocare, Inc., a Delaware corporation (the "Company"), and Clint B. Davis, an
individual resident of the State of California ("Employee").

1.      POSITION AND RESPONSIBILITIES

        a. POSITION. Employee is employed by the Company to render services to
the Company in the position of Senior Vice President, Legal Affairs and General
Counsel. Employee shall report directly to the Company's Chief Executive
Officer, subject to applicable legal requirements, including, without
limitation, Section 307 of the Sarbanes-Oxley Act of 2002 and the rules adopted
by the Securities and Exchange Commission thereunder. Employee shall perform
such duties and responsibilities as are normally related to such position, in
accordance with industry standards, and any additional duties now or hereafter
reasonably assigned to Employee by the Company or the Chief Executive Officer.
Employee shall abide by the Company's rules, regulations and policies, as
adopted or modified from time to time in the Company's sole discretion.

        b. OTHER ACTIVITIES. Except with the prior written consent of the
Company, Employee shall not, during the term of this Agreement, (i) accept any
other employment, or (ii) engage, directly or indirectly, in any other business
activity (whether or not pursued for pecuniary gain) that might interfere with
Employee's duties and responsibilities hereunder or create a conflict of
interest with the Company. Employee may serve as a member of the board of
directors of any company that does not compete with the Company. Notwithstanding
the foregoing, Employee may also devote reasonable time and attention to civic,
charitable or social organizations so long as such activities do not interfere
with the performance of his duties to the Company.

        c. NO CONFLICT. Employee represents and warrants that Employee's
execution of this Agreement, Employee's employment with the Company and the
performance of Employee's proposed duties under this Agreement shall not violate
any obligations Employee may have to any prior employer, or any other person or
entity, including, without limitation, any obligations with respect to
proprietary or confidential information of any prior employer, or any other
person or entity.

2.      COMPENSATION AND BENEFITS

        a. BASE SALARY. In consideration of the services to be rendered under
this Agreement, the Company shall pay to Employee a salary at the rate of
$238,000 per year (the "Base Salary"). The Base Salary shall be paid in
accordance with the Company's regular payroll practices. The Base Salary will be
reviewed from time to time in accordance with the Company's procedures for
adjusting salaries for senior executives and may be increased or decreased at
any time in the Company's sole discretion.


<PAGE>

        b. BONUS. Employee shall be eligible to receive an annual bonus of up to
forty percent (40%) of the Base Salary, subject to Employee's attainment of
corporate goals and objectives to be established in accordance with the
Company's Board-approved bonus plan, which may be modified at any time in the
Company's sole discretion.

        c. STOCK OPTIONS. The Company shall grant to Employee an option (the
"Option") to purchase two hundred fifty thousand (250,000) shares (the "Shares")
of the Company's Common Stock, $0.001 par value per share (the "Common Stock").
The exercise price per share of the Option shall be the fair market value of the
Common Stock on the grant date, as determined in accordance with the terms of
the Company's 2004 Stock Incentive Plan (the "2004 Plan"). The Option shall vest
as to twenty-five percent (25%) of the Shares at the end of the first
anniversary of the Effective Date and 1/48th of the Shares at the end of each
monthly anniversary of the Effective Date thereafter. The vesting of the Option
shall accelerate upon the occurrence of a Corporate Transaction or Change in
Control, as such terms are defined in the 2004 Plan. The Option shall expire on
the tenth (10th) anniversary of the grant date. Employee's entitlement to the
Option is conditioned upon the approval of the Company's Board of Directors. The
Option shall be subject to the terms and conditions of the 2004 Plan and the
Company's standard stock option agreement under the 2004 Plan.

        d. BENEFITS. As of the Effective Date, Employee shall be eligible to
participate in the benefits made generally available by the Company to
similarly-situated employees, in accordance with the benefit plans established
by the Company, as such plans may be amended from time to time in the Company's
sole discretion. The Company shall reimburse Employee for all costs incurred for
the purchase of COBRA coverage until such time that he and his dependents become
eligible to participate in the Group Health Plan.

        e. PAID TIME OFF. Employee shall receive four (4) weeks of paid time off
per calendar year. Employee may take such accrued paid time off at such times as
are mutually convenient to Employee and the Company. In addition, Employee shall
be entitled to all holidays provided under the Company's regular holiday
schedule.

        f. BUSINESS EXPENSES. The Company will reimburse Employee for reasonable
and necessary expenses appropriately incurred by Employee in performing his
duties and obligations to the Company in accordance with, and subject to, such
policies and procedures regarding executive officer expenses generally as the
Company may from time to time have in effect.

        g. RELOCATION REIMBURSEMENT. The Company shall reimburse Employee for
reasonable moving expenses, in an amount of up to $5,000. In addition, the
Company shall reimburse Employee for the amount of any home selling price
commission, in an amount of up to 5% of the selling price. If the home selling
price commission is less than 5%, then the Company shall split the difference
50/50 between the actual home selling price commission and 5%. For example, if
the actual home selling price commission is 3%, then the Company shall reimburse
Employee for 1.5% of the selling price.




                                       2
<PAGE>

3.      AT-WILL EMPLOYMENT

        a. AT-WILL TERMINATION BY COMPANY. The employment of Employee shall be
"at-will" at all times. The Company may terminate Employee's employment with the
Company at any time, without any advance notice, for any reason or no reason at
all, notwithstanding anything to the contrary contained in or arising from any
statements, policies or practices of the Company relating to the employment,
discipline or termination of its employees. Upon and after the date of such
termination, all obligations of the Company shall cease, except as set forth
below in Section 3(c).

        b. AT-WILL TERMINATION BY EMPLOYEE. Employee may terminate employment
with the Company at any time for any reason or no reason at all, upon two weeks'
advance written notice. During such notice period Employee shall continue to
diligently perform all of Employee's duties hereunder. The Company shall have
the option, in its sole discretion, to make Employee's termination effective at
any time prior to the end of such notice period as long as the Company pays
Employee all compensation (including all accrued Base Salary (as then in
effect), accrued, but unused Paid Time Off, and subject to payment of all
reimbursable expenses) incurred to which Employee is entitled up through the
last day of the two-week notice period. Any and all shares of Common Stock that
have vested under the Option (or any other Option that Employee shall receive
while employed by the Company hereunder) shall continue to belong to Employee,
subject to the terms of exercise set forth in the related option agreements.
Thereafter all obligations of the Company shall cease, except as set forth below
in Section 3(c).

        c. TERMINATION BY COMPANY WITHOUT CAUSE OR BY EMPLOYEE FOR GOOD REASON.

        (i) If at any time the Company terminates Employee's employment other
than for Cause (as defined below), or if at any time Employee terminates his
employment for Good Reason (as defined below), then, during the period of time
from the termination date until the first anniversary of the termination date
(the "Severance Term"), the Company shall (A) pay to Employee the Base Salary,
in accordance with the Company's payroll practices (the "Salary Severance
Benefit"), and (B) make available to Employee the benefits made generally
available by the Company to its employees, to the extent permitted under
applicable law and the terms of the benefit plans. Notwithstanding anything in
this Agreement to the contrary, if required to comply with the provisions of
Section 409A of the Internal Revenue Code of 1986, as amended, then: (A) the
Salary Severance Benefit for the first six (6) months of the Severance Term
shall accrue during such six (6) months, but shall not be paid to Employee until
the first day of the seventh month of the Severance Term; and (B) Employee shall
pay the life insurance premiums and such other benefit expenses (as may be
required under Section 409A of the Internal Revenue Code) applicable to the
first six (6) months of the Severance Term, for which Employee shall be
reimbursed on an after-tax basis on the first day of the seventh month of the
Severance Term.

        (ii) The Company's termination of Employee's employment shall be for
"Cause" if Employee: (A) exhibits willful misconduct or dishonesty; (B) is
convicted of a felony; (C) acts (or fails to act) in the performance of his
duties to the Company in bad (good) faith and to the Company's detriment; (D)
materially breaches this Agreement or any other agreement; or



                                       3
<PAGE>

(E) engages in misconduct that is demonstrably and materially injurious to the
Company, including, without limitation, willful and material failure to perform
his duties as an officer or employee of the Company or excessive absenteeism
unrelated to illness or vacation.

        (iii) Employee's termination of his employment shall be for "Good
Reason" if Employee terminates his employment: (A) within the thirty (30)-day
period immediately following the six (6)-month anniversary of the date of the
occurrence of a Change in Control (as defined below); (B) within six (6) months
of the Company's material reduction of Employee's level of responsibility; or
(C) within six (6) months of the Company's material reduction of the Base
Salary, except for any salary reduction that is generally applicable to the
Company's executives.

        (iv) For purposes of this Agreement, the term "Change in Control" shall
mean any of the following transactions:

                (A) a merger or consolidation in which the Company is not the
        surviving entity, except for a transaction the principal purpose of
        which is to change the state in which the Company is incorporated;

                (B) the sale, transfer or other disposition of all or
        substantially all of the assets of the Company;

                (C) any reverse merger in which the Company is the surviving
        entity but in which securities possessing more than fifty percent (50%)
        of the total combined voting power of the Company's outstanding
        securities are transferred to a person or persons different from those
        who held such securities immediately prior to such merger; or

                (D) the acquisition in a single or series of related
        transactions by any person or related group of persons (other than by
        the Company or by a Company-sponsored employee benefit plan) of
        beneficial ownership (within the meaning of Rule 13d-3 of the Securities
        Exchange Act of 1934, as amended) of securities possessing more than
        fifty percent (50%) of the total combined voting power of the Company's
        outstanding securities.

        (v) Employee's right to receive any payments or other benefits under
this Section 3(c) is expressly conditioned upon: (A) Employee's execution of a
general release of all claims as of the date of Employee's termination, in
substantially the form attached to this Agreement as Exhibit A (the "General
Release"); and (B) Employee's compliance with his obligations under this
Agreement, the General Release and all other agreements between Employee and the
Company.

4.      TERMINATION OBLIGATIONS

        a. RETURN OF PROPERTY. Employee agrees that all property (including,
without limitation, all equipment, tangible proprietary information, documents,
records, notes, contracts and computer-generated materials) furnished to or
created or prepared by Employee incident to



                                       4
<PAGE>

Employee's employment belongs to the Company and shall be promptly returned to
the Company upon termination of Employee's employment.

        b. COOPERATION. Following any termination of employment, Employee shall
perform any and all acts reasonably requested by the Company to ensure the
orderly and efficient transition of Employee's duties. Such acts may include,
but are not limited to: (i) participating in meetings or telephone conferences;
(ii) reviewing, preparing or executing documents; and (iii) providing assistance
in connection with any litigation, investigation or audit involving the Company,
or any of its affiliates, directors, officers, employees, agents, attorneys,
representatives, stockholders, insurers, divisions, successors and/or assigns
and any related holding, parent or subsidiary corporations. To the extent
Employee is required to perform any material services after the Severance Period
has expired, the Employee's performance of such services shall be contingent
upon the Company compensating the Employee for time and expenses on a
predetermined, reasonable, and mutually agreed upon rate of compensation.

5.      NON-DISCLOSURE OF THIRD-PARTY INFORMATION

Employee represents and warrants and covenants that Employee shall not disclose
to the Company, or use, or induce the Company to use, any proprietary
information or trade secrets of others at any time, including but not limited to
any proprietary information or trade secrets of any former employer, if any; and
Employee acknowledges and agrees that any violation of this provision shall be
grounds for Employee's immediate termination and could subject Employee to
substantial civil liabilities and criminal penalties. Employee further
specifically and expressly acknowledges that no officer or other employee or
representative of the Company has requested or instructed Employee to disclose
or use any such third-party proprietary information or trade secrets. Employee
also agrees to maintain as confidential any information protected by federal or
state attorney-client privilege doctrines during and after employment, except to
the extent disclosure is compelled by lawful process or authorized by the
Company.

6.      PROPRIETARY INFORMATION; NON-INTERFERENCE; AND NON-SOLICITATION

        a. PROPRIETARY INFORMATION: For purposes of this Agreement, "Proprietary
Information" means all information and any idea in whatever form, tangible or
intangible, whether disclosed to or learned or developed by Employee, pertaining
in any manner to the business of the Company or to the Company's affiliates
(including subsidiaries), consultants, customers, and business associates,
unless: (i) the information is or becomes publicly known through lawful means;
(ii) the information was rightfully in Employee's possession or part of his
general knowledge prior to his employment by the Company; or (iii) the
information is disclosed to Employee without confidential or proprietary
restriction by a third party who rightfully possesses the information and did
not learn of it, directly or indirectly, from the Company. Employee further
understands that the Company considers the following information to be included,
without limitation, in the definition of Proprietary Information: (a)
techniques, development tools, formulas, processes, computer printouts, computer
programs, and design



                                       5
<PAGE>

manuals; (b) information about costs, profits, revenues, margins, and markets;
(c) plans for future development and new product concepts; (d) customer names,
addresses, telephone numbers, facsimile numbers, credit card numbers, contact
persons, and customer preferences; (e) marketing and product plans, bidding
information, costs of product, services and other items, proposal information,
proposal methods and policies, price schedules, product profit margins, price
setting methods and policies, customer service methods and policies and service
plans and policies; (f), patterns and processes, compilations, discoveries,
inventions, programs, and devices, (g) the Company's business plans, accounting
records, computer records, computer systems, networking and telecommunication
systems, management information systems and programs, audits and other financial
data related to products and services provided by the Company; and (h) labor
rates, commission rates and plans, commission schedules, employee lists,
employee performance evaluations and related information, employee titles,
outside contracting sources and rates, benefit costs and research reports.

        b. NON-DISCLOSURE: Employee agrees that his work with the Company will
involve access to and creation of Proprietary Information. Employee further
agrees to hold all Proprietary Information in strict confidence and never to use
or disclose any Proprietary Information to anyone at any time, including after
the termination of his employment, except to the extent necessary to carry out
his responsibilities as an employee of the Company, or as specifically
authorized in writing by an authorized officer of the Company, other than
Employee.

        c. NON-INTERFERENCE AND NON-SOLICITATION: Employee acknowledges and
agrees that the Company's relationships with its employees, consultants,
customers, vendors and service providers are valuable business assets.
Accordingly, Employee agrees that, during his employment with the Company and
for a period of two (2) years after the date of any termination of such
employment, he will not (for himself or for any third party) divert or attempt
to divert from the Company any business, employee, consultant, customer, vendor
or service provider, through solicitation or otherwise, or otherwise interfere
with the Company's business or the Company's relationships with its employees,
consultants, customers, vendors and service providers.

7.      AMENDMENTS; WAIVERS; REMEDIES

This Agreement may not be amended or waived except by a writing signed by
Employee and by a duly authorized officer of the Company. Failure to exercise
any right under this Agreement shall not constitute a waiver of such right. Any
waiver of any breach of this Agreement shall not operate as a waiver of any
subsequent breaches. All rights or remedies specified for a party herein shall
be cumulative and in addition to all other rights and remedies of the party
hereunder or under applicable law.

Notwithstanding the foregoing, Employee acknowledges that the Company, in the
exercise of its sole discretion and without the consent of Employee, may amend
or modify this Agreement in any manner and delay the payment of any severance or
other benefits payable pursuant to this Agreement to the minimum extent
necessary to meet the requirements of Section 409A of the



                                       6
<PAGE>

Internal Revenue Code as amplified by any Internal Revenue Service or U.S.
Treasury Department guidance as the Company deems appropriate or advisable.

8.      ASSIGNMENT; BINDING EFFECT

        a. ASSIGNMENT. The performance of Employee is personal hereunder, and
Employee agrees that Employee shall have no right to assign and shall not assign
or purport to assign any rights or obligations under this Agreement. This
Agreement may be assigned or transferred by the Company; and nothing in this
Agreement shall prevent the consolidation, merger or sale of the Company or a
sale of any or all or substantially all of its assets.

        b. BINDING EFFECT. Subject to the foregoing restriction on assignment by
Employee, this Agreement shall inure to the benefit of and be binding upon each
of the parties; the affiliates, officers, directors, agents, successors and
assigns of the Company; and the heirs, devisees, spouses, legal representatives
and successors of Employee.

9.      NOTICES

All notices or other communications required or permitted hereunder shall be
made in writing and shall be deemed to have been duly given if delivered: (a) by
hand; (b) by a nationally recognized overnight courier service; or (c) by United
States first class registered or certified mail, return receipt requested, to
the principal address of the other party, as set forth below on the signature
page of this Agreement. The date of notice shall be deemed to be the earlier of
(i) actual receipt of notice by any permitted means, or (ii) three business days
following dispatch by overnight delivery service or the United States mail.
Employee shall be obligated to notify the Company in writing of any change in
Employee's address. Notice of change of address shall be effective only when
provided in accordance with this Section 9.

10.     SEVERABILITY

If any provision of this Agreement shall be held by a court or arbitrator to be
invalid, unenforceable or void, such provision shall be enforced to the fullest
extent permitted by law, and the remainder of this Agreement shall remain in
full force and effect. In the event that the time period or scope of any
provision is declared by a court or arbitrator of competent jurisdiction to
exceed the maximum time period or scope that such court or arbitrator deems
enforceable, then such court or arbitrator shall reduce the time period or scope
to the maximum time period or scope permitted by law.

11.     TAXES

All amounts paid under this Agreement (including, without limitation, the Base
Salary) shall be paid less all applicable state and federal tax withholdings,
and any other withholdings that are agreed upon or required by any applicable
jurisdiction.



                                       7
<PAGE>

12.     GOVERNING LAW

This Agreement shall be governed by and construed in accordance with the
internal laws of the State of California, without regard to conflicts of law
principles.

13.     INTERPRETATION

This Agreement shall be construed as a whole, according to its fair meaning, and
not in favor of or against any party. Sections and section headings contained in
this Agreement are for reference purposes only, and shall not affect in any
manner the meaning or interpretation of this Agreement. Whenever the context
requires, references to the singular shall include the plural and the plural the
singular.

14.     OBLIGATIONS SURVIVE TERMINATION OF EMPLOYMENT

Employee agrees that any and all of the Company's and the Employee's obligations
under this Agreement shall survive the termination of his employment and the
termination of this Agreement.

15.     COUNTERPARTS

This Agreement may be executed in any number of counterparts, each of which
shall be deemed an original of this Agreement, but all of which together shall
constitute one and the same instrument.

16.     AUTHORITY

Each party represents and warrants that such party has the right, power and
authority to enter into and execute this Agreement and to perform and discharge
all of the obligations hereunder; and that this Agreement constitutes the valid
and legally binding agreement and obligation of such party and is enforceable in
accordance with its terms.

17.     ENTIRE AGREEMENT

This Agreement is intended to be the final, complete and exclusive statement of
the terms of Employee's employment by the Company and may not be contradicted by
evidence of any prior or contemporaneous statements or agreements.
Notwithstanding the foregoing, this Agreement shall not supersede or otherwise
affect any agreements previously or concurrently executed by Employee relating
to the Company's proprietary information or intellectual property rights, or
relating to Employee's non-interference or non-solicitation obligations relative
to the Company's business or employees. To the extent that the practices,
policies or procedures of the Company, now or in the future, apply to Employee
and are inconsistent with the terms of this Agreement, the provisions of this
Agreement shall control. Any subsequent change in Employee's duties, position or
compensation shall not affect the validity or scope of this Agreement.



                                       8
<PAGE>

18.     EMPLOYEE ACKNOWLEDGEMENT

Employee acknowledges that Employee has had the opportunity to consult legal
counsel concerning this Agreement, that Employee has read and understands this
Agreement, that Employee is fully aware of its legal effect and that Employee
has entered into this Agreement freely based on Employee's own judgment and not
on any representations or promises other than those contained in this Agreement.

19.     ARBITRATION

        a. ARBITRABLE DISPUTES: The Company and Employee hereby agree that, to
the fullest extent permitted by law, any and all claims or controversies between
them (or between Employee and any present or former officer, director, agent, or
employee of the Company or any parent, subsidiary, or other entity affiliated
with the Company), including without limitation any claims arising under this
Agreement, shall be resolved by final and binding arbitration.

        b. ARBITRATION RULES: Any arbitration proceeding shall be conducted in
accordance with the National Rules for the Resolution of Employment Disputes of
the American Arbitration Association (the "AAA Rules"); shall take place in
Irvine, California, unless otherwise agreed by the parties; and shall be
conducted before an experienced arbitrator who has been selected in accordance
with the AAA Rules. The arbitrator shall apply the same substantive law, with
the same statutes of limitations and same remedies that would apply if the
claims were brought in a court of law.

        c. FEES AND COSTS: Each party shall pay its own costs and attorney's
fees, unless a party prevails on a statutory claim, and the statute provides
that the prevailing party is entitled to payment of its attorneys' fees. In that
case, the arbitrator may award reasonable attorneys' fees and costs to the
prevailing party as provided by law. The Company agrees to pay the costs and
fees of the arbitrator to the extent required by law.

        d. WAIVER OF JURY TRIAL: The parties understand and agree that the
agreement to arbitrate as specified in this Agreement constitutes a waiver of
the right to a trial by jury of any claims or controversies. The parties agree
that no arbitrable disputes shall be resolved by a jury trial. Nothing in this
Agreement precludes either party from filing an administrative charge before an
agency that has jurisdiction over an arbitrable claim. Moreover, nothing in this
Agreement prohibits either party from seeking provisional relief pursuant to
California Code of Civil Procedure Section 1281.8.

                            [SIGNATURE PAGE FOLLOWS]



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<PAGE>

        IN WITNESS WHEREOF, the parties hereby execute this Agreement as of the
Effective Date.

ENDOCARE, INC.                              EMPLOYEE:




By:     /s/  Craig T. Davenport             /s/  Clint B. Davis
   ---------------------------------        ------------------------------------
Name:   Craig T. Davenport                  Clint B. Davis
Title:  Chairman and Chief Executive
        Officer



Address for notices:                        Address for notices:

201 Technology Drive                        P.O. Box 3081
Irvine, CA  92618                           Rancho Santa Fe, CA  92067
Attention:  Chief Executive Officer




                    [SIGNATURE PAGE TO EMPLOYMENT AGREEMENT]



                                       10
<PAGE>

                                    EXHIBIT A
                                 GENERAL RELEASE


             SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS

This Severance Agreement and Release of All Claims ("Agreement") is made by and
between Endocare, Inc. ("the Company") and           ("Employee") based on the
following facts:


                a. Employee is employed by the Company as its         .

                b. Employee's employment was terminated, with the last day of
work being effective __________________________ and termination date being
effective            (the "Separation Date").

                c. The Company has offered, and Employee has accepted,
additional severance benefits, to which the Employee is not otherwise entitled,
in exchange for (i) a general release of all claims, (ii) Employee's agreement
to hold in strict confidence all confidential or proprietary information
(including, without limitation, all trade secrets) relating directly or
indirectly to the Company, and (iii) the other terms and conditions set forth
herein.

                d. This Agreement is therefore entered into by the Company and
Employee to document the parties' agreement regarding the terms of Employee's
separation from the Company.

        WHEREFORE, the Company and Employee agree as follows:

        1. On          , the Company will deliver Employee's final paycheck. The
amount will represent all accrued wages, salary, bonuses, accrued but unused
Paid Time Off pay, and any similar payments due and owing to Employee from the
Company as of the Separation Date, with the exception of any Salary Severance
Benefit that may be due under the terms of the 2006 Employment Agreement between
the Company and Employee. The Company will deduct normal withholding and
appropriate deductions from the final paycheck. At that time Employee will
acknowledge that the Company does not owe any other amounts, excluding any
applicable earned commissions due, Salary Severance Benefits, and reimbursable
expenses. Applicable earned commissions due and reimbursable expenses will be
paid to Employee according to regular commission and expense payment procedures.
Commission procedures include payment upon completion of condition precedents,
as detailed in the current Commission Program. Expense procedures include
payment upon receipt of approved expense reports, receipts, and similar
documentation. Salary Severance Benefits will be paid to Employee according to
the terms of the 2006 Employment Agreement between the Company and Employee.

        2. Employee agrees to promptly return all materials relating directly or
indirectly to the Company remaining in Employee's possession or under his
control, including but not limited to credit cards, hardware, software,
equipment, key fobs, office keys, source code, data, resources, and documents.
EMPLOYEE AGREES TO PROMPTLY RETURN COMPANY LAPTOP AND OTHER HARDWARE, EQUIPMENT,
AND RESOURCES WITHOUT REMOVING, DELETING, OR ALTERING ANY COMPANY PROPERTY,
INCLUDING BUT NOT LIMITED TO, ELECTRONIC MAIL, SOFTWARE, COMPUTER FILES,
RESOURCE LISTS, AND ALL OTHER COMPANY DOCUMENTS. EMPLOYEE ALSO AGREES TO
PROMPTLY DESTROY, DELETE OR RETURN TO THE COMPANY, AT THE COMPANY'S OPTION, ALL
RECORDS (IN WHATEVER FORM,



                                      -1-
<PAGE>

WHETHER PAPER, ELECTRONIC OR OTHERWISE) OF ANY NATURE (INCLUDING, WITHOUT
LIMITATION, ELECTRONIC MAIL, INSTANT MESSAGES AND TEXT MESSAGES) RELATING
DIRECTLY OR INDIRECTLY TO THE COMPANY. Employee also agrees to promptly return
any subsequently discovered materials relating directly or indirectly to the
Company.

        3. In consideration for the promises and representations of Employee as
described in this Agreement, the Company will:

                a. Pay Employee the aggregate gross amount of eight (8) weeks of
base salary (        ), less applicable withholding taxes, which shall be in
addition to any Salary Severance Benefits that may be due under Section 3 of the
2006 Employment Agreement between the Company and Employee, and which Employee
is not otherwise entitled to receive ("Supplemental Severance Payments"). These
Supplemental Severance Payments shall be paid to Employee in equal semi-monthly
installments, scheduled to coincide with the Company's regular payroll.
Employee's receipt of the Supplemental Severance Payments shall be contingent
upon Employee's compliance with all of the terms of this Agreement and all of
the terms of the Employee Invention and Confidentiality Agreement previously
executed by Employee in favor of the Company. Employee will have twenty-one (21)
days from Employee's termination date, to decide whether to enter into this
Agreement. Employee is not required to use the full twenty-one (21) days.
Employee is advised to consult with an attorney regarding this Agreement before
signing this Agreement. Once Employee has signed the Agreement, Employee will
then have seven (7) days in which Employee may revoke the Agreement. Employee's
revocation must be in writing and received by Suzanne Ryberg, Vice President,
Human Resources, within the seven-day period in order to be effective. This
Agreement will not become effective or enforceable until seven (7) days after
Employee signs the Agreement, provided Employee does not revoke it, or upon
Employee's return of all Company property, whichever date is later. If Suzanne
Ryberg does not receive the signed Agreement by 5:00 PM (the close of business)
on      ,        , the Company will assume Employee is not interested in such an
Agreement and the offer will be withdrawn.

                b. In the event that Employee is not otherwise entitled to
continued employee benefits under Section 3 of the terms of the 2006 Employment
Agreement between the Company and Employee, the Company shall pay the Company's
portion of the benefit premium(s) on Employee's behalf for the months of
provided Employee timely elects to continue current participation in the
Company's group health insurance plans pursuant to the terms of the Consolidated
Omnibus Budget Reconciliation Act ("COBRA") and provided Employee does not
otherwise become eligible to participate in another employer's group insurance
plan. The Company's portion of the benefit premium(s) are as follows:          .
The Employee's portion of the benefit premium(s) are as follows:         . If
Employee desires to continue participation beyond        200   , Employee
understands and agrees that Employee shall be fully responsible for making the
total necessary premium payments in order to continue such coverage. Nothing
herein shall limit the right of the Company to change the provider and/or the
terms of its group health insurance plans at any time hereafter.

        4. Employee understands and agrees that there is a limited period of
time from the Separation Date in which to exercise all or a portion of
Employee's vested stock options, and



                                      -2-
<PAGE>

acknowledges that Employee has a copy of the Company's stock option plan.
Furthermore, Employee acknowledges receipt of Employee's stock "Termination
Status" statement, which provides a detail of Employee's exercisable stock
options, price, and final date to exercise.

        5. For good and valuable consideration, Employee hereby releases the
Company, and its successors and assigns, as well as any past or present
directors, officers, agents, shareholders or employees of the Company
(collectively, "Releasees"), from any and all claims arising out of Employee's
employment or the termination of employment from the Company. This release is
intended to be interpreted broadly and is intended to include, without
limitation, all common law claims (including but not limited to: breach of
contract, breach of the covenant of good faith and fair dealing, wrongful
discharge in violation of public policy, infliction of emotional distress,
negligence, invasion of privacy, interference with contractual relationship,
defamation and fraud), as well as any statutory claims (including but not
limited to claims arising under: the Age Discrimination in Employment Act as
amended, 29 U.S.C. Section 621 et seq.; Title VII of the Civil Rights Act of
1964, as amended by the Civil Rights Act of 1991, 42 U.S.C. Section 2000 et
seq.; the Civil Rights Act of 1866, 42 U.S.C. Section 1981; the Family and
Medical Leave Act of 1993, 29 U.S.C. Section 2601 et seq.; the Americans with
Disabilities Act of 1990, 42 U.S.C. Section 12101 et seq.; the False Claims Act
, 31 U.S.C. Section 3729 et seq.; the Fair Labor Standards Act, 29 U.S.C.
Section 215 et seq., as well as claims under the California Fair Employment and
Housing Act, Cal. Govt. Code Section 12900 et seq.; the California False Claims
Act, Cal. Govt. Code Section 12650 et seq.; the California Corporate Criminal
Liability Act, Cal. Penal Code Section 387; or under the California Labor Code
and any other federal, state or local laws and regulations relating to
employment, conditions of employment (including wage and hour laws), perquisites
of employment (including but not limited to claims relating to stock and/or
stock options) and/or employment discrimination), or any other claim whatsoever
arising out of Employee's employment or the termination of employment. Claims
not covered by the release provisions of this Agreement are (i) claims for
unemployment insurance benefits, (ii) claims under the California Workers'
Compensation Act and (iii) claims arising from the covenants and promises
contained within this Agreement.

        6. Employee hereby agrees that Employee may have had access to
confidential or proprietary information relating to the Company. Confidential or
proprietary information includes, without limitation: any trade secret;
technical know-how; information; data; knowledge; idea; design; formula;
instrument; product; machinery; project; equipment; document; file; photograph;
computer printout; drawing; sketch or other visual representation; data
processing or computer software technique, program or system; biological,
chemical, mechanical or other invention; improvement; discovery; composition;
process; part of a process; manufacturing technique; book; notebook; paper;
compilation of information; record; specification; operating method; patent
disclosure or patent application; list or other written record used in the
Company's business; compensation and other terms of employment of the Company's
employees and consultants; names and practices of any customers or potential
customers of the Company and its affiliates; names, marketing methods, operating
practices and related data regarding the Company's existing and potential
vendors, suppliers, distributors, joint venture partners, and affiliates; the
marketing methods and plans of the Company and its affiliates, licensors and
licensees and related data and prices at which the Company obtains or has
obtained, or at which it sells or has sold, its products or services; research,
development, manufacturing and sales plans, costs and receipts of the Company;
and any other information,



                                      -3-
<PAGE>

ideas or materials relating to the past, present, planned or foreseeable
business, products, developments, technology or activities of Company. Employee
acknowledges that this information is confidential or proprietary and agrees not
to disclose it, nor allow it to be disclosed, communicated or otherwise conveyed
to any third parties (including, without limitation, to any competitor of the
Company) except as may be required by law. Employee further agrees to
immediately inform the Company in writing of any unauthorized disclosure of, or
access to, the Company's confidential or proprietary information. Employee
hereby agrees that the disclosure of the Company's confidential or proprietary
information shall cause serious damage to the Company. EMPLOYEE ACKNOWLEDGES
THAT EMPLOYEE WOULD BE SUBJECT TO CRIMINAL AND/OR CIVIL LIABILITY FOR DISCLOSURE
OF ANY SUCH INFORMATION. Employee's obligations under this Section 6 shall be in
addition to, and not in lieu of, Employee's obligations under the Employee
Invention and Confidentiality Agreement previously executed by Employee in favor
of the Company.

        7. Employee waives all the benefits and rights granted to Employee
pursuant to California Civil Code section 1542, which provides:

        A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT
        KNOW OR SUSPECT TO EXIST IN HIS/HER FAVOR AT THE TIME EXECUTING THE
        RELEASE, WHICH, IF KNOWN BY HIM/HER MUST HAVE MATERIALLY AFFECTED
        HIS/HER SETTLEMENT WITH THE DEBTOR.

        8. Employee acknowledges and agrees that Employee has no pending
lawsuit, administrative charge or complaint against the Company or any of the
other Releasees, in any court or with any governmental agency. Employee also
agrees that, to the extent permitted by law, Employee will not allow any
lawsuit, administrative charge or complaint to be pursued on the Employee's
behalf. Employee further agrees that Employee will not participate, cooperate or
assist in any litigation against the Releasees in any manner, to the extent
permitted by law. If lawfully subpoenaed by a court of this jurisdiction,
Employee agrees to provide the Company written notice of such a subpoena within
five (5) days of receipt.

        9. By entering into this Agreement, Employee agrees that none of the
Releasees have engaged in or are presently engaging in any unlawful conduct of
any sort. It is understood and agreed that this Agreement is not an admission of
liability and shall not be used or construed as such in any proceeding.

        10. Employee further agrees that Employee will not disparage, defame,
slander, or otherwise detrimentally comment upon the Releasees or act in any
manner that may tend to harm the Company's business or reputation, including
their business practices or products, in any manner. Employee acknowledges that
such comment shall cause serious damage to the Company.

        11. Employee further agrees, covenants, and represents that for one year
following termination, Employee will not solicit (i) any employee to leave the
Company, (ii) any business of any customers or (iii) any potential acquisition
target of the Company for purposes of acquiring such target as outlined within
the Employee Invention and Confidentiality Agreement executed by Employee in
favor of the Company.



                                      -4-
<PAGE>

        12. Employee promises and agrees that, unless compelled by legal
process, Employee will not disclose to others and will keep confidential both
the fact of and the terms of this Agreement, including the amounts referred to
in this Agreement, except that Employee may disclose this information to
Employee's spouse and attorneys, accountants, and other professional advisors to
whom the disclosure is necessary to accomplish the purposes for which Employee
has consulted such professional advisors and who agree to keep such information
confidential. Employee expressly promises and agrees that, unless compelled by
legal process, Employee will not disclose to any present or former employees of
the Company the fact or the terms of this Agreement.

        13. Employee and the Company hereby agree and understand that each party
to this Agreement shall bear their own respective attorneys' fees and expenses
related to the negotiation and preparation of this Agreement, and that each
agrees to hold the other harmless from the payment of all such attorneys' fees
and expenses.

        14. This Agreement shall be construed under the laws of the State of
California.

        15. Any disputes between Employee and any Releasee, arising out of or in
any way connected to the terms of this Agreement, or the parties' rights or
obligations with respect to Employee's separation from the Company, shall be
resolved by binding arbitration before a single arbitrator pursuant to the then
current Employment Dispute Resolution Rules of the American Arbitration
Association. The prevailing party in such arbitration shall be entitled to an
award of costs and attorneys' fees in connection with the arbitration.

        16. Employee agrees that this Agreement has been negotiated and that no
provision contained herein shall be interpreted against any party because that
party drafted the provision.

        17. In the event that any provision of this Agreement shall be found to
be unenforceable, that provision shall be deemed deleted, and the validity and
enforceability of the remaining provisions shall not be affected.

        18. This Agreement contains the entire agreement between the parties on
the subjects addressed in this Agreement and replaces any other prior agreements
between the parties. This Agreement may only be modified in a written document
signed by an officer of the Company.

                            [SIGNATURE PAGE FOLLOWS]



                                      -5-
<PAGE>

        BY SIGNING BELOW, Employee certifies that Employee has read and
understands all of this Agreement, has received any advice or counsel the
Employee deems necessary regarding this Agreement, and is entering into this
Agreement freely and voluntarily, intending to be bound by its terms.





Dated:
       -------------------              ----------------------------------------



                                        ENDOCARE, INC.


Dated:
       -------------------              ----------------------------------------
                                        SUZANNE RYBERG
                                        VICE PRESIDENT, HUMAN RESOURCES


   [SIGNATURE PAGE TO SEPARATION AGREEMENT AND GENERAL RELEASE OF ALL CLAIMS]



                                      -6-