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Exhibit 4.3  


THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUED

UPON ITS EXERCISE ARE SUBJECT TO THE RESTRICTIONS ON

TRANSFER SET FORTH IN SECTION 4 OF THIS WARRANT  



	Warrant No. CS - 003	 	Number of Shares: 50,000
	

Date of Issuance: April 30, 2002	
 	

 




 
 

Beyond Genomics, Inc.    
    
    Common Stock Purchase Warrant    
    
    (Void after April 30, 2012)    
    


        Beyond Genomics, Inc., a Delaware corporation (the "Company"), for value received, hereby certifies that Boston University School of Medicine, a
non-profit, tax-exempt educational institution organized under the laws of Massachusetts, or its registered assigns (the "Registered Holder"), is entitled, subject to the terms
and conditions set forth below, to purchase from
the Company, at any time or from time to time on or after the date of issuance and on or before 5:00 p.m. (Boston time) on April 30, 2012, 50,000 shares of Common Stock, $.001 par value
per share, of the Company, at a purchase price of $1.50 per share. The shares purchasable upon exercise of this Warrant, and the purchase price per share, each as adjusted from time to time pursuant
to the provisions of this Warrant, are hereinafter referred to as the "Warrant Shares" and the "Purchase Price," respectively. 


        1.    Exercise.    



        (a)   This
warrant may be exercised by the Registered Holder, in whole or in part, by: (i) surrendering this Warrant, with the purchase form appended hereto as  Exhibit I (the "Exercise Form") completed
to reflect an exercise for cash and duly executed by the Registered Holder or by the Registered
Holder's duly authorized attorney, at the principal office of the Company, or at such other office or agency as the Company may designate, accompanied by payment in full, in lawful money of the United
States, of the Purchase Price payable in respect of the number of Warrant Shares purchased upon such exercise; or (ii) surrendering this Warrant, with the Exercise Form completed to reflect a
cashless exercise and duly executed by the Registered Holder or by the Registered Holder's duly authorized attorney, at the principal office of the Company, or at such other office or agency as the
Company may designate. If the Company shall effect a firm commitment underwritten public offering of shares of Common Stock, then, effective immediately prior to the closing of the sale of such shares
by the Company pursuant to such public offering, this Warrant shall be deemed to be automatically exercised in full, without any further action taken by the holder hereof, by means of a cashless
exercise pursuant to Section l (a)(ii) hereof. 


        (b)   Each
exercise of this Warrant shall be deemed to have been effected immediately prior to the close of business on the day on which this Warrant shall have been
surrendered to the Company as provided in subsection 1(a) above (the "Exercise Date"). At such time, the person or persons in whose name or names any certificates for Warrant Shares shall be issuable
upon such exercise as provided in subsection 1 (c) below shall be deemed to have become the holder or holders of record of the Warrant Shares represented by such certificates. 


        (c)   As
soon as practicable after the exercise of this Warrant in full or in part, and in any event within 30 days thereafter, the Company, at its expense, will cause
to be issued in the name of, and delivered to, the Registered Holder, or as such Holder (upon payment by such Holder of any applicable transfer taxes) may direct on the Exercise Form delivered at the
time of exercise of this Warrant: 



          (i)  in
the event of a cash exercise pursuant to Section 1 (a)(i), a certificate or certificates for the number of full Warrant Shares to which the Registered Holder
shall be entitled upon 









 


such
exercise plus, in lieu of any fractional share to which the Registered Holder would otherwise be entitled, cash in an amount determined pursuant to Section 3 hereof; 


         (ii)  in
the event of a cashless exercise pursuant to Section 1 (a)(ii) hereof, a certificate or certificates for the number of Warrant Shares to which the
Registered Holder shall be entitled upon such exercise computed using the following formula plus, in lieu of any fractional share to which the Registered Holder would otherwise be entitled, cash in an
amount determined pursuant to Section 3 hereof: 




	 	 	X =	 	Y(A-B)
 A	 	 








Where:



	X
	=
the number of Warrant Shares to be issued;



	Y
	=
the number of shares of Common Stock as to which the Registered Holder exercised the Warrant;



	A
	=
Fair Market Value per share of Common Stock at the time of exercise of the Warrant (determined pursuant to Section 3 hereof);



	B
	=
Purchase Price in effect at the time of exercise of the Warrant; and 





        (iii)  in
case either such exercise is in part only, a new warrant or warrants (dated the date hereof) of like tenor, calling in the aggregate on the face or faces thereof
for the number of Warrant Shares equal (without giving effect to any adjustment therein) to the number of such shares called for on the face of this Warrant minus the number of such shares as to which
the Registered Holder exercised the Warrant. 





        2.    Adjustments.    



        (a)    Adjustment for Stock Splits and Combinations.    If the Company shall at any time or from time to time after
the date on which this Warrant was first issued (the "Original Issue Date") effect a subdivision of the outstanding Common Stock, the Purchase Price then in effect immediately before that subdivision
shall be proportionately decreased. If the Company shall at any time or from time to time after the Original Issue Date combine the outstanding shares of Common Stock, the Purchase Price then in
effect immediately before the combination shall be proportionately increased. Any adjustment under this paragraph shall become effective at the close of business on the date the subdivision or
combination becomes effective. 


        (b)    Adjustment for Certain Dividends and Distributions.    In the event the Company at any time, or from time to
time after the Original Issue Date shall make or issue, or fix a record date for the determination of holders of Common Stock entitled to receive, a dividend or other distribution payable in
additional shares of Common Stock, then and in each such event the Purchase Price then in effect immediately before such event shall be decreased as of the time of such issuance or, in the event such
a record date shall have been fixed, as of the close of business on such record date, by multiplying the Purchase Price then in effect by a fraction: 



        (1)   the
numerator of which shall be the total number of shares of Common Stock issued and outstanding immediately prior to the time of such issuance or the close of business
on such record date, and 


        (2)   the
denominator of which shall be the total number of shares of Common Stock issued and outstanding immediately prior to the time of such issuance or the close of
business 




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on
such record date plus the number of shares of Common Stock issuable in payment of such dividend or distribution; 




provided,
however, if such record date shall have been fixed and such dividend is not fully paid or if such distribution is not fully made on the date fixed therefor, the Purchase Price shall be
recomputed accordingly as of the close of business on such record date and thereafter the Purchase Price shall be adjusted pursuant to this paragraph as of the time of actual payment of such dividends
or distributions. 


        (c)    Adjustment in Number of Warrant Shares.    When any adjustment is required to be made in the Purchase Price
pursuant to Section 2(a) or 2(b), the number of Warrant Shares purchasable upon the exercise of this Warrant shall be changed to the number determined by dividing (i) an amount equal to
the number of shares issuable upon the exercise of this Warrant immediately prior to such adjustment, multiplied by the Purchase Price in effect immediately prior to such adjustment, by
(ii) the Purchase Price in effect immediately after such adjustment. 



        (d)    Adjustments for Other Dividends and Distributions.    In the event the Company at any time or from time to time
after the Original Issue Date shall make or issue, or fix a record date for the determination of holders of Common Stock entitled to receive, a dividend or other distribution payable in securities of
the Company (other than shares of Common Stock) or in cash or other property (other than cash out of earnings or earned surplus, determined in accordance with generally accepted accounting
principles), then and in each such event provision shall be made so that the Registered Holder shall receive upon exercise hereof, in addition to the number of shares of Common Stock issuable
hereunder, the kind and amount of securities of the Company and/or cash and other property which the Registered Holder would have been entitled to receive had this Warrant been exercised into Common
Stock on the date of such event and had the Registered Holder thereafter, during the period from the date of such event to and including the Exercise Date, retained any such securities receivable,
giving application to all adjustments called for during such period under this Section 2 with respect to the rights of the Registered Holder. 


        (e)    Adjustment for Mergers or Reorganizations, etc.    If there shall occur any reorganization, recapitalization,
consolidation or merger involving the Company in which the Common Stock is converted into or exchanged for securities, cash or other property (except if, but only to the extent that, an appropriate
adjustment is made pursuant to subsection 2(a), 2(b) or 2(d)), then, following any such reorganization, recapitalization, consolidation or merger, the Registered Holder shall receive upon exercise
hereof the kind and amount of securities, cash or other property which the Registered Holder would have been entitled to receive if, immediately prior to such reorganization, recapitalization,
consolidation or merger, the Registered Holder had held the number of shares of Common Stock subject to this Warrant. In any such case, appropriate adjustment (as determined in good faith by the Board
of Directors of the Company) shall be made in the application of the provisions set forth herein with respect to the rights and interests thereafter of the Registered Holder, to the end that the
provisions set forth in this Section 2 (including provisions with respect to changes in and other adjustments of the Purchase Price) shall thereafter be applicable, as nearly as reasonably may
be, in relation to any securities, cash or other property thereafter deliverable upon the exercise of this Warrant. 


        (f)    Certificate as to Adjustments.    Upon the occurrence of each adjustment or readjustment of the Purchase Price
pursuant to this Section 2, the Company at its expense shall promptly compute such adjustment or readjustment in accordance with the terms hereof and furnish to the Registered Holder a
certificate setting forth such adjustment or readjustment (including the kind and amount of securities, cash or other property for which this Warrant shall be exercisable and the Purchase Price) and
showing in detail the facts upon which such adjustment or readjustment is based. The Company shall, upon the written request at any time of the Registered Holder, furnish 



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or
cause to be furnished to the Registered Holder a certificate setting forth (i) the Purchase Price then in effect and (ii) the number of shares of Common Stock and the amount, if any,
of other securities, cash or property which then would be received upon the exercise of this Warrant. 




        3.    Fractional Shares.    The Company shall not be required upon the exercise of this Warrant to issue any
fractional shares, but shall make an adjustment therefor in cash on the basis of the Fair Market Value per share of Common Stock as of the Exercise Date. The Fair Market Value per share of Common
Stock shall be determined as follows: 



        (a)   If
the Common Stock is listed on a national securities exchange, the Nasdaq National Market or another nationally recognized trading system as of the Exercise Date, the
Fair Market Value per share of Common Stock shall be deemed to be the average of the high and low reported sale prices per share of Common Stock thereon on the trading day immediately preceding the
Exercise Date (provided that if no such price is reported on such day, the Fair Market Value per share of Common Stock shall be determined pursuant to subsection 3(b)). 


        (b)   If
the Common Stock is not listed on a national securities exchange, the Nasdaq National Market or another nationally recognized trading system as of the Exercise Date,
the Fair Market Value per share of Common Stock shall be deemed to be the amount most recently determined by the Board of Directors to represent the fair market value per share of the Common Stock
(including without limitation a determination for purposes of granting Common Stock options or issuing Common Stock under an employee benefit plan of the Company); and, upon request of the Registered
Holder, the Board of Directors (or a representative thereof) shall promptly notify the registered Holder of the Fair Market Value per share of Common Stock. Notwithstanding the foregoing, if the Board
of Directors has not made such a determination within the three-month period prior to the Exercise Date, then (i) the Board of Directors shall make a determination of the Fair Market Value per
share of the Common Stock within 15 days of a request by the Registered Holder that it do so, and (ii) the exercise of this Warrant pursuant to this subsection 3(b) shall be delayed
until such determination is made. 




        4.    Requirements for Transfer.    



        (a)   This
Warrant and the Warrant Shares shall not be sold or transferred unless either (i) they first shall have been registered under the Securities Act of 1933, as
amended (the "Act"), or (ii) the Company first shall have been furnished with an opinion of legal counsel, reasonably satisfactory to the Company, to the effect that such sale or transfer is
exempt from the registration requirements of the Act. 


        (b)   Notwithstanding
the foregoing, no registration or opinion of counsel shall be required for (i) a transfer by a Registered Holder which is a corporation to a
wholly owned subsidiary of such corporation, a transfer by a Registered Holder which is a partnership to a partner of such partnership or a retired partner of such partnership or to the estate of any
such partner or retired partner, or a transfer by a Registered Holder which is a limited liability company to a member of such limited liability company or a retired member or to the estate of any
such member or retired member, provided that the transferee in each case agrees in writing to be subject to the terms of this Section 4, or (ii) a transfer made in accordance with
Rule 144(k) under the Act. 


        (c)   Each
certificate representing Warrant Shares shall bear a legend substantially in the following form: 



"The
securities represented by this certificate have not been registered under the Securities Act of 1933, as amended, and may not be offered, sold or otherwise transferred, pledged or hypothecated
unless and until such securities are registered under such Act or an opinion of counsel satisfactory to the Company is obtained to the effect that such registration is not required." 




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        The
foregoing legend shall be removed from the certificates representing any Warrant Shares, at the request of the holder thereof, at such time as they become eligible for resale
pursuant to Rule 144(k) under the Act. 




        5.    No Impairment.    The Company will not, by amendment of its charter or through reorganization, transfer of
assets, consolidation, merger, dissolution, issue or sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but
will at all times in good faith assist in the carrying out of all Such terms and in the taking of all such action as may be necessary or appropriate in order to protect the rights of the holder of
this Warrant against impairment. 


        6.    Notices of Record Date, etc.    In the event: 



        (a)   the
Company shall set a record date for determining the holders of its Common Stock (or other stock or securities at the time deliverable upon the exercise of this
Warrant) for the purpose of entitling or enabling them to receive any dividend or other distribution, or to receive any right to subscribe for or purchase any shares of stock of any class or any other
securities, or to receive any other right; or 


        (b)   of
any capital reorganization of the Company, any reclassification of the Common Stock of the Company, any consolidation or merger of the Company with or into another
corporation (other than a consolidation or merger in which the Company is the surviving entity and its Common Stock is not converted into or exchanged for any other securities or property), or any
transfer of all or substantially all of the assets of the Company; or 


        (c)   of
the voluntary or involuntary dissolution, liquidation or winding-up of the Company, 




then,
and in each such case, the Company will mail or cause to be mailed to the Registered Holder a notice specifying, as the case may be, (i) the record date for such dividend, distribution or
right, and the amount, character and nature of such dividend, distribution or right, or (ii) the effective date on which such reorganization, reclassification, consolidation, merger, transfer,
dissolution, liquidation or winding-up is to take place, and the time, if any is to be fixed, as of which the holders of record of Common Stock (or such other stock or securities at the
time deliverable upon the exercise of this Warrant) shall be entitled to exchange their shares of Common Stock (or such other stock or securities) for securities or other property deliverable upon
such reorganization, reclassification, consolidation, merger, transfer, dissolution, liquidation or winding-up. Such notice shall be mailed at least ten days prior to the record date or
effective date for the event specified in such notice. 


        7.    Reservation of Stock.    The Company will at all times reserve and keep available solely for issuance and
delivery upon the exercise of this Warrant, such number of Warrant Shares and other securities, cash and/or property, as from time to time shall be issuable upon the exercise of this Warrant. 


        8.    Exchange of Warrants.    Upon the surrender by the Registered Holder, properly endorsed, to the Company at the
principal office of the Company, the Company will, subject to the provisions of Section 4 hereof, issue and deliver to or upon the order of such Registered Holder, at the Company's expense, a
new Warrant or Warrants of like tenor, in the name of the Registered Holder or as the Registered Holder (upon payment by the Registered Holder of any applicable transfer taxes) may direct, calling in
the aggregate on the face or faces thereof for the number of shares of Common Stock (or other securities, cash and/or property) then issuable upon exercise of this Warrant. 


        9.    Replacement of Warrants.    Upon receipt of evidence reasonably satisfactory to the Company of the loss, theft,
destruction or mutilation of this Warrant and (in the case of loss, theft or destruction) upon delivery of an indemnity agreement (with surety if reasonably required) in an amount reasonably 


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satisfactory
to the Company, or (in the case of mutilation) upon surrender and cancellation of this Warrant, the Company will issue, in lieu thereof, a new Warrant of like tenor. 


        10.    Transfers, etc.    



        (a)   The
Company will maintain a register containing the name and address of the Registered Holder of this Warrant. The Registered Holder may change its or his address as
shown on the warrant register by written notice to the Company requesting such change. 



        (b)   Subject
to the provisions of Section 4 hereof, this Warrant and all rights hereunder are transferable, in whole or in part, upon surrender of this Warrant with a
properly executed assignment (in the form of Exhibit II hereto) at the principal office' of the Company. 


        (c)   Until
any transfer of this Warrant is made in the warrant register, the Company may treat the Registered Holder as the absolute owner hereof for all purposes;  provided, however, that if and when this Warrant is properly assigned in blank, the Company may (but
shall not be obligated to) treat the bearer hereof as the absolute owner hereof for all purposes, notwithstanding any notice to the contrary. 




        11.    Mailing of Notices, etc.    All notices and other communications from the Company to the Registered Holder
shall be mailed by first-class certified or registered mail, postage prepaid, to the address last furnished to the Company in writing by the Registered Holder. All notices and other communications
from the Registered Holder or in connection herewith to the Company shall be mailed by first-class certified or registered mail, postage prepaid, to the Company at its principal office set forth
below. If the Company should at any time change the location of its principal office to a place other than as set forth below, it shall give prompt written notice to the Registered Holder and
thereafter all references in this Warrant to the location of its principal office at the particular time shall be as so specified in such notice. 


        12.    No Rights as Stockholder.    Until the exercise of this Warrant, the Registered Holder shall not have or
exercise any rights by virtue hereof as a stockholder of the Company. Notwithstanding the foregoing, in the event (i) the Company effects a split of the Common Stock by means of a stock
dividend and the Purchase Price of and the number of Warrant Shares are adjusted as of the date of the distribution of the dividend (rather than as of the record date for such dividend), and
(ii) the Registered Holder exercises this Warrant between the record date and the distribution date for such stock dividend, the
Registered Holder shall be entitled to receive, on the distribution date, the stock dividend with respect to the shares of Common Stock acquired upon such exercise, notwithstanding the fact that such
shares were not outstanding as of the close of business on the record date for such stock dividend. 


        13.    Change or Waiver.    Any term of this Warrant may be changed or waived only by an instrument in writing signed
by the party against which enforcement of the change or waiver is sought. 


        14.    Section Headings.    The section headings in this Warrant are for the convenience of the parties and in no way
alter, modify, amend, limit or restrict the contractual obligations of the parties. 


        15.    Governing Law.    This "Warrant will be governed by and construed in accordance with the internal laws of the
Commonwealth of Massachusetts (without reference to the conflicts of law provisions thereof). 


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        EXECUTED as of the Date of Issuance indicated above. 



	 	 	Beyond Genomics, Inc.
	

 	
 	

By:	
 	

/s/  ILLEGIBLE      

	

 	
 	

Title:	
 	
President

	

ATTEST:	
 	

 	
 	

 
	

/s/  ILLEGIBLE      
	
 	

 	
 	

 




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   EXHIBIT I  


PURCHASE FORM  



	To:	 	 
	 	 	 	Dated:	 	 






        The
undersigned, pursuant to the provisions set forth in the attached Warrant (No.             ), hereby irrevocably elects to
purchase            shares of the Common
Stock covered by such Warrant. 


        If
"Cash Exercise" is checked below, the undersigned herewith makes payment of the full purchase price for such shares at the price per share provided for in such Warrant, which is
$            in lawful money of the United States. 



	 	 	Signature:	 	 

	 	 	Address:	 	 
 






        Check
one of the following: 



        o Cash
Exercise 



        o Cashless Exercise 



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   EXHIBIT II  


ASSIGNMENT FORM  


        FOR VALUE RECEIVED,                        hereby sells, assigns
and transfers all of the rights of the undersigned under the attached Warrant
(No.             ) with respect to the number of shares of Common Stock covered thereby set forth below, unto: 



	Name of Assignee
 
	 	Address
	 	No. of Shares

	 	 	 	 	 
	 	 	 	 	 
	 	 	 	 	 





	Dated:	 	 
	 	Signature:	 	 





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Beyond Genomics, Inc. Common Stock Purchase Warrant (Void after April 30, 2012)