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### US **E NVIRONMENTAL PROTECTION AGENCY**  **(EPA) FIFRA SCIENTIFIC ADVISORY PANEL (SAP)** 

**OPEN MEETING CHLORPYRIFOS HEALTH EFFECTS** 

**A PRIL 10** 

**– 13, 2012**  **PANEL MEMBER BIOGRAPHIES**

**FI FRA Scientific Advisory Panel Members**  **Kenneth M. Portier, Ph.D. (FIFRA SAP Chair)** Dr. Kenneth M. Portier is Director for Statistics at the American Cancer Society home office in Atlanta, Georgia, Courtesy Associate Professor of Statistics in the Institute of Food and Agricultural Sciences at the Universit y of Florida, Gainesville, Flori da, and Courtesy Professor of Biostatistics at Emory

University , Atlanta, Georgia. A native of south Louisiana, Dr. Portier received a BS in mathematics (1973) from Nicholls State University , Thibodaux, L ouisiana, and a MS in Statistics (1975) and PhD in B iostatistics (1979) from the University of North Carolina, Chapel Hill. With ACS since early 2006, Dr. Portier provides general statistical support to cancer researchers in the area of design and anal ys is of cross

- sectional and longitudinal sample survey s , program evaluation and cancer modeling. Prior to ACS he spent 27 y ears as a statistical consultant to researchers in agriculture, natural resources and the environment and as a teacher of applied statistics at the graduate level at UF. Dr. Portier has c o - authored over 150 publications in many of the premier journals in agriculture, natural resources and environmental sciences. He has received national recognition for his teaching and twice participated in USDA

- funded teaching grants, one on new methods for teaching natural resources sampling and the other to develop a stud y abroad course in natural resources assessment with the Czech Republic. His collaborations with other researchers at UF have resulted in 36 funded research grants from numerous agencie s including NSF, USDA, NOAA, EPA, and DOI. He continues to collaborate with UF's Center for Environmental and Human Toxicology on statistical questions that arise in environmental sampling and risk assessments. He has been a regular member of US EPA (FIF RA

- SAP) and National Toxicology Program (NIH

- NI EHS) science advisory panels reviewing human and ecological risks. His research interests are wide, including the application of new statistical methodologies to cancer research and environmental problems. H is statistical interests are in multivariate methods. He continues his interest in the teaching of statistics.2

**Stephen J. Klaine, Ph.D.** Stephen J. Klaine is a professor in the Department of Biological Sciences and director of the Institute of Environmental Toxicology (CU

- ENTOX) at Clemson University

. He received his doctorate from the Department of Environmental Science and Engineering, Rice University in 1982 and has spent over 25 y ears conducting environmental research and educating graduate students. He has 30 Ph.D. and over 40 MS graduates from his laboratory . He has served on the board of directors of the Society of Environmental Toxicology and Chemistry

and has been an associate editor for the journal, Environmental Toxicology and Chemistry

for 15 y ears. He has been on the editorial board of the journal, Nanotoxicology , since 2009. From 1995 to 2000 he was the onl y US participant on a multi

- national International Atomic Energy Agency Cooperative Research Program on Pesticides in Coastal Tropic al Ecosy stems. In addition to building capacit y in tropical countries around the world this group produced the first book to compile pesticide use and effects information in tropical countries. Klaine was a co

- editor of this book. Klaine has served on se veral USEPA Science Advisory Panels and workshops dealing with pesticide and metal fate, effects, and risk assessment. He has also served on the NRC panel to review the National Nanotechnology I nitiative Strategy

on Environmental and Human Safety Needs fo r Nanomaterials. He has served on the NIEHS review panel for the Superfund Basic Research Program since 1995 and chaired the panel in 2007 and 2008. He has severed on several other proposal review panels for the USEPA, USDA, and NIEHS. He has been a Sig ma Xi National Lecturer, won the Clemson University Sigma Xi researcher of the y ear in 2007, and won the Clemson University Alumni Award for Outstanding Research in 2009. He has over 110 peer - reviewed publications on research ranging from the bioavailabil ity and toxicity

of pesticides and metals to pesticide risk assessment, to the environmental behavior and toxicity of nanomaterials. Current research in his laboratory focuses on characterizing 1) the bioavailablity of metals and pesticides in aquatic s ys tems; 2) the comparative ph yt otoxicity of pesticides; 3) the response of aquatic organisms to episodic contaminant exposures; 4) the water qualit y consequences of land use; 5) the effects of pharmaceuticals on fish behavior; and 5) the bioavailability

and toxicity

of colloids and nanoparticles in aquatic s ys tems. **Carey Pope, Ph.D.** Dr. Carey Pope is Professor, Head and Sitlington Chair in Toxicology in the Department of Phy siological Sciences at the Oklahoma State University Center for Veterinary

Health Scie nces, Stillwater, Oklahoma. He received a Ph.D. degree from the Universit y of Texas Graduate School of Biomedical Sciences in Houston, Texas in 1985, and completed postdoctoral training in the Neurology

Department at Baylor College of Medicine (1985) and the U.S. Environmental Protection Agency ’s National Health and Environmental Effects Research Laboratory (1986

- 1989). He previously

served on the faculty

of the College of Pharmacy , University of Louisiana at Monroe (1989

- 1999). Dr. Pope’s research primaril y involves the evaluation of intrinsic and extrinsic factors that modify neurotoxicity

from exposure to acetylcholinesterase inhibitors. He has previousl y served as a consultant for the U.S. Army’s external research programs, was a member of the NAS/NRC Subcommittee on Toxicologic Assessment of Low

- Level Exposures to Chemical Warfare Agents and is currentl y a member of the NIEHS Neurotoxicology and Alcohol study

section. Dr. Pope has been a member of the Food Qualit y Protection Act Board since 1996.3

**Martha Sandy, Ph.D.**  Dr. Martha S. Sand y is a Senior Toxicologist and Chief of the Cancer Toxicology and Epidemiology

Section within the California Environmental Protection Agency ’s (Cal/EPA) Office of Environmental Health Hazard Assessment (OEHHA). Dr. Sand y’s Section conducts hazard identification, dose

- response assessment, and exposure assessment of chemical carcinogens. Children’s environmental health, and in particular, cancer risk associated with earl y life carcinogen exposures, has been a significant focu s in recent y ears. Her group is comprised of individuals with expertise in toxicology , epidemiology , biostatistics and exposure assessment. Dr. Sand y has a Ph.D. and an M.P.H. in Environmental Health Sciences, with an emphasis in Toxicology , from the Uni versit y of California, Berkeley ’s School of Public Health. She conducted research investigating biochemical and molecular mechanisms of toxicity and carcinogenicity , and biochemical and genetic susceptibility factors in Parkinson’s disease before joining OEHHA in 1994. Dr. Sand y currentl y serves on the U.S. EPA’s Children’s Health Protection Advisory

Committee and has served as an ad hoc member of two U.S. Environmental Protection Agency

(U.S. EPA) Scientific Review panels, as a member of two National Aca dem y committees, as a member of one Report on Carcinogens Expert panel, and as a peer reviewer for the National Research Council.4

**FQ PA Science Review Board Members**  **Michael Aschner, Ph.D.** Dr. Aschner earned his B.S. from the University of Rochester, Rochester, NY, in 1980, and his Ph.D. in Anatomy

and Neurobiology

from the University

of Rochester School of Medicine and Dentistry , Rochester, NY, in 1985. After a brief postdoctoral fellowshi p in Toxicology (at the same Institution), he assumed his first facult y position (Assistant followed by Associate Professorship) in the Department of Pharmacology at Alban y Medical College, Alban y, NY (1988

- 1994). For the next decade he joined the Departm ent of Ph ys iology and Pharmacology

at Wake Forest University

School of Medicine, Winston

- Salem, NC. As of 2004, Dr. Aschner serves as the Gray

E. B. Stahlman Professor of Neuroscience in the Department of Pediatrics at the Vanderbilt University Medical Ce nter in Nashville, TN. He also holds joint appointments at the Kenned y Center for Research on Human Development and in the Department of Pharmacology

and is the Director of the Division of Clinical Pharmacology and pediatric Toxicology . Dr. Aschner is al so the Director of the Molecular Toxicology Center and the Toxicology

Training (as of October 2011). Dr. Aschner has served on numerous national and international toxicology

panels (Institute of Medicine, US Environmental Protection Agency , Center for Dis ease Control), served and chaired the Neurotoxicology and Alcohol (NAL) National Institutes of Health Study Section, and authored approximately 450 peer

- reviewed manuscripts and chapters in the area of neurotoxicology . He serves as Associate Editor (Neuro toxicology ; Toxicological Science; Neurochemistry Research; Biology

Trace Elements Research) and on the Editorial Boards (Toxicology; Acta Neurobiologiae Experimentalis; Alcohol; Frontiers in Genomics) of several journals and he edited several books relate d to Neurotoxicology . He is a member of the Societ y of Toxicology , Society for Neuroscience, a Fellow of the Academy

of Toxicological Sciences and a past president of the International Neurotoxicology

Association. In 2011, he was the recipient of the Soc iety of Toxicology

Merit Award. He presently

also serves as Vice

- President Elect of the International Society of Trace Elements Research in Humans. Dr. Aschner’s research interests are in the neurobiology and phy siology

of astrocy

tes and the mechanisms o f central nervous s ys tem injury . Dr. Aschner has been particularl y interested in metal uptake and distribution in the brain, devoting the last 25 ye ars of his research to the mechanisms of transport of methylmercury , manganese, and uranium across the capi llaries composing the blood

– brain barrier, as well as their cellular and molecular mechanisms of neurotoxicity . Studies in the lab address basic mechanisms in various experimental models (C. elegans, tissue cultures and rodents) as well as follow

- up on th e sequalae of manganese deposition in the brains of human neonates.5

**Brian Buckley, Ph.D.** Dr. Buckley

is the Executive Director of Laboratories at the Environmental and Occupational Health Sciences Institute at Rutgers University . He received his BS in Chemistry form University

of New Hampshire, his PhD in Analy tical Chemistry

from North Carolina State University

and was a post doctoral fellow at Oak Ridge National Lab. He is a member of the graduate facult y in Environmental Sciences, Toxicology and Public Health at Rutgers University and the Universit y of Medicine and Dentistry of New Jersey. He is a member of the American Chemical Society

and the Society

of Applied Spectroscopy and was honored as the Virgil Pay ne Award for Outstanding Chemical Ser vice Achievement and has served on multiple review panels for NIH and EPA FIFRA. His research focus is on anal yt ical methods development and modification to measure xenobiotic molecules and their metabolites including pesticides, PCBs plasticizers and other endocrine disrupting compounds prevalent in the environment. In addition he ha s developed methods for metals measurement and metals speciation by plasma mass spectrometry

. His most recent research has been in developing in

- vitro models for phy siological processes and creating metabolic profiles of specific environmental contaminant s such as estrogen mimics. Dr. Buckley has authored/coauthored more than 60 research articles/book chapters including a key

paper in evaluating pesticide use in the home and made more than 100 presentations on measurement of contaminants prevalent in envi ronmental health. Dr. Buckley has developed anal yt ical methods for many human biomonitoring studies including; NHEXAS, CL EARS, the Childhood Autism Study and currently

the National Children’s Study in Queen’s county NY. He has appeared on ABC News, Ey ewi tness news, Fox 5 News NY, News 12 NJ and NJN news discussing topics of environmental contamination and human health.
**Russell Carr , Ph.D.** 
Dr. Russell Carr is an Associate Professor in the Center for Environmental Health Sciences in the College of Veterinary

Medicine at Mississippi State University . He received his dual B.S. in Biology and Chemistry

(1987) from Delta State University , Cleveland, Mississippi, and his M.S. in Zoology

(1990) and Ph.D. in Animal Phy siology (1994) from Mis sissippi State University

. Prior to serving in his current faculty position, Dr. Carr completed postdoctoral training (1995) and served as a Research Toxicologist (1995

- 1999) at Mississippi State. Dr. Carr’s primary research interests are in the area of developmental neurotoxicology with emphasis on environmental chemicals. One focus is investigating the mechanisms b y which developmental organophosphorus insecticide exposure alters the neurochemistry of the brain and induces long

term changes in behavior . Another focus is the development of a short lived aquatic vertebrate model to study

the lifetime effects of developmental exposure. Dr. Carr is currentl y the Research Coordinator/Evaluator for the Indianola Promise Community of the Delta Health Allianc e. He is active in both the national and local chapters the Societ y of Toxicology. Dr. Carr has served as an ad hoc panel member of several U.S. EPA FIFRA Scientific Advisory Panels.6

**Abby C. Collier, Ph.D.** Dr. Abb y C. Collier is an Assistant Professor of Pharmacology at the John A. Burns School of Medicine, Universit y of Hawaii. Originall y from New Zealand, Dr. Collier received her B.Sc. in Pharmacology

from the University

of Auckland (1998) and her PhD in Pharmacology from the same institution in 2003. After performing a Post Doctoral Fellowship at the Universit y of Nevada Reno under Dr. Chris Pritsos, Dr. Collier was appointed Assistant Professor of Pharmacology

at the University

of Hawaii Medical School in 2006. Dr. Collier teaches Pharmacology

to undergraduate and graduate students as well as Clinical Pharmacology for medical students and was awarded the University of Hawaii Regent’s Medal for Teaching in 2011. Within Pharmacology , her sub

- specialty is drug metabolism and pharmacokinetics, primarily focused on research in pregnancy and pediatrics. A winner of the 2011 SimCYP award for Most Informative Paper (“in recognition of scientific research that is leading the world in ADME, IVIVE, pharmacokinetics, modeling and simulation”); Dr. Collier uses a combination of wet laboratory

work and in silico modeling to provide greater understanding of developmental pharmacology

as well as improve drug and chemical safety . Dr. Collier’s research laboratory has been funded b y the National Institutes of Health and private Foundations since 2007. Along with her collaborators, she also performs research and publishes regularl y in the fields of human and environmental toxicology and in endocrinology

. **Ellen Gold, Ph.D.**
Dr . Ellen B. Gold is Chair of the Department of Public Health Sciences and Chief of the Division of Epidemiology

in that Department in the University of California Davis School of Medicine and former Chair of the Graduate Group in Epidemiology . After receivi ng her PhD, she became a facult y member at The Johns Hopkins University until she moved to the UC Davis facult y in 1988. She has been Principal Investigator on a number of NIH

- funded, peer

- reviewed grants and has had continuous NIH research grant funding f or over 20 y ears. These research grants have largel y focused over the past 30 years on lifest yl e and environmental factors that affect women’s reproductive health and cancer risk and include her work for the past 15 y ears studying the natural history

of the menopausal transition, including hormonal and s ymptomatic changes, in a longitudinal study

of a large, multi

- racial/ethnic national cohort. She has also authored or co

authored over 150 peer

- reviewed publications. She has mentored numerous graduate st udents and junior facult y and has received a number of outstanding faculty and mentoring awards, is co

Director of the UC Davis Building Interdisciplinary Research Careers in Women's Health program and is a Fellow in the American Association for the Advanc ement of Science.7

**Gaylia Jean Harry, Ph.D.**
Dr. Jean Harry

is currently

Head of the Neurotoxicology Group in the Laboratory

of Neurobiology

at the National Institute of Environmental Health Sciences, National Institutes of Health (NIH) in Resear ch Triangle Park, North Carolina. She has adjunct appointments in the Toxicology

Programs of both University of North Carolina/Chapel Hill and Duke Universit y. She has previousl y served as Acting Laboratory Chief of the Laboratory

of Molecular Toxicology

at NIEHS and has work as a neurotoxicology discipline leader within the National Toxicology

Program. She received her Ph.D. from Virginia Commonwealth University in 1981 and subsequentl y completed additional training in a NIH Training Program in Neuropathology followed b y the award of a NIH individual postdoctoral fellowship in biochemistry/toxicology at the University

of North Carolina/Chapel Hill. She joined N IEHS in 1990 as Head of the Developmental Neurotoxicology Group and has been Head of the Neurotoxicology Group since 1995. She has an active research program in the area of neuroimmunotoxicology in the immature and aged nervous sy stem. She has served on numerous national and international committees and working groups with reference to neurotoxicology including the World Health Organization, USEPA, International L ife Sciences Institute, as well as state and local environmental agencies. **Stella Koutros, P**

**h.D.** Dr. Stella Koutros is a Research Fellow in the Occupational and Environmental Epidemiology Branch (OEEB) at the Division of Cancer Epidemiology and Genetics (DCEG) of the National Cancer Institute (NCI) at the National Institutes of Health in Bethesda , Mary land. Dr Koutros received her B.S at Tufts University (2002) and an M.P.H (2004) from Yale University . In 2006 Dr. Koutros came to the NCIand Ph.D. (2008) from Yale Universit y. Since 2006 when Dr. Koutros arrived at the NCIto complete her Ph.D. (2008) as part of a cooperative training program between DCEG and Yale University , she has worked extensively on occupational pesticide exposures as risk factors for cancer risk, particularl y within the Agricultural Health Study (AHS). Dr. Koutros has foc used her research in three primary areas, including, the etiology of cancers of the prostate and bladder, and the effect of pesticide exposure on cancer risk. She has lead several AHS analy ses to understand the impacts of pesticides on the overall
cancer incidence, the impact of specific chemicals, and the site

- specific associations between pesticide exposure and prostate and bladder cancer risk in the cohort

. Dr. Koutros has also lead work to explore gene

- environment interactions as risk factors for canc er, in particular the interaction between organophosphate insecticides and genetics as risk factors for prostate cancer. Dr. Koutros has provided peer review of manuscripts for many journals and given several invited lectures and additional presentations of her work within the Agricultural Health Study . Dr. Koutros continues her work on agricultural risk factors for cancer as well as risks from other occupational exposures.8

**Chensheng (Alex) Lu, Ph.D.**

Dr. Lu is an Associate Professor of Environmental Exposure Biology in the Department of Environmental Health, Harvard School of Public Health. He received the Ph.D. degree in Environmental Health from the University of Washington (Seattle, WA) in 1996. He was an Ass istant Professor at the Rollins School of Public Health, Emory University

in Atlanta GA from 2004 to 2008, before joining Harvard School of Public Health in 2008. His primary research interest is to assess human exposure to environmental chemicals, such a s pesticides and endocrine disruptors, using biomarker approach and to link exposures to health outcomes. His extramural research program consists of funding mainly from National Institute of Environmental Health Sciences (NIEHS) and US EPA’s Science to Ac hieved Results program (STAR). The current ongoing research projects include a communit y - based intervention study aiming to reduce young children’s exposures to pesticides via the implementation of the Integrated Pest Management (I PM) practice in one of the Boston Housing Authority developments, which he serves as the Principal Investigator (PI). He is also a PIof a study to determine how chronic exposures to endocrine disrupting chemicals would affect epigenetic methylation in children, and a co

- investi gator in a study to examine the interplay

between liver enzy mes and BPA/phthalates in relations to ty pe - 2 diabetes risk. He recently completed a random

- sampling population

- base study aiming to assess how the variations of dietary consumption patterns affe ct pesticide exposures. He is the author over 50 peer

- reviewed articles. He currentl y serves as an ad hoc member on the Scientific Advisory Panel established by

US EPA Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and b y US EPA Food Quality Protection Act (FQPA). He is a member of Scientific Experts of European Food Safet y Authority (EFSA) sinc e 2009. He also serves as the Associate Editor, Environmental Health Perspectives (EHP) and the Journal of Exposure Science and Environmental Epidemiology (JESEE), two leading scientific peer

- review journals in the field of Environmental Health.

**Bette Me ek, Ph.D.** 
Dr. Bette Meek is currently the Associate Director of Chemical Risk Assessment with the McLaughlin Institute of the Universit y of Ottawa on interchange from Health Canada, where she managed the Existing Substances Division in the Safe Environme nts Program. Her responsibilities in this capacity related to development and implementation of process and methodology

for the assessment of the effects on human health of Existing Substances under the Canadian Environmental Protection Act, including sett ing priorities for assessment from among all 23, 000 commercial chemicals used in Canada by September, 2006 (i.e., categorization). She has considerable experience in the development of methodology for and evaluation of health

related data on environmenta l contaminants, having also managed previously programs within Health Canada on contaminants of drinking water and air. She acts as an advisor to several international organizations and has authored over 150 scientific publications in this area. S pecific areas of experience include development of frameworks to increase transparency in the assessment of human relevance of animal modes of action, increasing incorporation of biological data in dose

- response as a replacement for default, development of predic tive exposure and hazard modeling and increasing efficiency in assessment through effective problem formulation and earl y and continuing peer engagement.9

**William Popendorf, Ph.D.** Dr. William Popendorf is a Professor of Industrial Hygiene at Utah State Un iversity

. He has been on the Board of the American Industrial Hygiene Association and a Director of the American Board of Industrial Hy giene. Dr. Popendorf has taught and conducted research for over thirty

y ears and published more than 65 papers, book chapters, and one text book beginning with pesticide hazards to farm workers in 1972

- 1992, inorganic dusts in 1978

- 1982, organic dusts from grains and livestock in 1982

- 1995, and automotive industry foundries and metal working fluids in 1987

- 1994, and broader reviews since 1991 culminating in 2006 with Industrial Hygi ene Control of Airborne Chemical Hazards. His broad interest has been to develop o r/and appl y predictive models (man y developed in other fields) that describe how phy sical mechanisms cause (and can be used to control) exposures of workers to organic vapors, hazardous particulate aerosols, and dermally toxic chemicals, with the expectati on that such tools will improve the overall practice and knowledge

- base of industrial h ygiene. **Barry Ryan, Ph.D.** Dr. Ry an is Professor of Exposure Science and Environmental Chemistry in the Department of Environmental Health, Rollins School of Public Heal th, Emory Universit y. He is jointly appointed in the Department of Chemistry at Emory University

. Prior to joining the facult y at Emory in 1995, he was on the facult y at Harvard School of Public Health. He received a BS in Chemistry

from the University of Massachusetts, an MS in Phy sical Chemistry from the University

of Chicago, and PhD in Computational Chemistry from Wesleyan Universit y. He has been active in the exposure assessment field for over 25 years publishing in excess of 100 peer

reviewed manu scripts and book chapters and making over 190 presentations of his work to the scientific community

. His work has included both cross

- sectional and longitudinal studies of community

- based exposure for multiple pollutants in multiple media. Dr. Ry an is Pr incipal Investigator of a retrospective study of exposure to perfluorooctanoic acid in a large area surrounding a manufacturing facility using this compound. Recently , he began work assessing exposure to pesticides experienced b y individuals in a community in Northern Thailand. In addition, he is Co

- Principal Investigator and Co

- Investigator on three separate Formative Research projects associated with the National Children’s Study

. Recent work completed by Dr. Ry an’s group includes a U.S. EPA

- funded STA R Grant designed to assess the effectiveness of biological markers of exposure to organophosphate and p yrethroid pesticides and a stud y if the impact on the surrounding communit y of airport emissions of various airborne compounds. Dr. Ry an is a member of the Executive Committee of the Emory /Battelle/ Morehouse consortium for the National Children’s Study

. He was Principal Investigator on the U.S. EPA funded longitudinal study

of exposures to pollutants known as the National Human Exposure Assessment (NHEX AS)

- Mary land study , and was Co

- Principal Investigator of a study on health

- compromised individuals assessing the impact of particulate matter exposure on heart rate variability , and Co

- Principal Investigator on a study of the impact of air pollution expo sure on hiker lung

- health in the Great Smoky Mountain National Park. Dr R yan is a member of the Board of Scientific Counselors for U.S. EPA’s Office of Research and Development and a member of the US EPA Science Advisory Board Sub

- Committee on Exposure an d Human10

Health. Dr. R yan also completed a four

- ye ar term on the Federal Advisory Committee for the National Children’s Study being undertaken b y the National Institutes of Health. He has served on numerous advisory

panels for the U.S. EPA, most recentl y as the Chair of the external evaluation committee on the Draft Exposure Factors Handbook update and on the FIFRA SAP on Chlorpy

rifos PBPK

- Cares Modeling Review. Dr. Ry an has also served on several National Academ y of Science panels. **Alvin V. Terry Jr., P**

**h.D.** Dr. Alvin V. Terry

Jr. is a tenured Professor of Pharmacology and Toxicology

and Director of the Animal Behavior Center at Georgia Health Sciences University (GHSU) in Augusta, Georgia. He also holds joint appointments as Professor of Neurology and G raduate Studies at GHSU, and is a licensed pharmacist in Georgia and South Carolina. A native of South Carolina, Dr. Terry received a B.S. in Pharmacy from the Medical Universit y of South Carolina, Charleston, S.C. in 1982 and a Ph.D. in Pharmacology from the Universit y of South Carolina, Columbia, S.C. in 1991. He received post

- doctoral training and served as a junior facult y member at the Medical College of Georgia from 1991

- 1994, then served as a facult y member of the University

of Georgia College of P harmacy from 1994 until taking his current position at GHSU Department of Pharmacology and Toxicology

in December of 2005. To date, Dr. Terry has published 133 peer

- reviewed research articles, 8 book chapters, and holds 1 US patent. His research is currently

supported by

the National Institute of Environmental Health Sciences (NIEHS), the National Institute on Aging (NIA), and the National Institute on Drug Abuse (NIDA). Dr. Terry

has served on multiple study sections for a variet y of governmental agencie s including The National Institutes of Health, NASA and The Department of Veterans Affairs. Dr. Terry 's research interests focus on the role of central acet yl choline (i.e., cholinergic) pathway s in cognition; specifically

how these neuronal pathway s are involved in the memory dy sfunction associated with neurops ychiatric illnesses and exposures to environmental toxins, especially organophosphates. The actions of both pharmaceutical and toxicological agents on the cholinergic neuronal s ys tem, axonal transport, as well as the major growth factors (nerve growth factor, brain derived growth factor) that support the cholinergic s ys tem are of particular interest. The laboratory

also focuses on drug discovery and development strategies for the treatment of disorders of cognition. The laboratory employ s a variet y of methods to test hy potheses ranging from b ehavioral testing in animal models (rodents to non

- human primate) to molecular, cellular and anal yt ical techniques.11

**John E. Vena, Ph.D.**
Dr. John E. Vena is the Head of the Department of Epidemiology and Biostatistics and University

of Georgia Foun dation Professor in Public Health at the College of Public Health, University

of Georgia. From 2003

- 2008 he served as Professor and Chair of the Department of Epidemiology

and Biostatistics at the Arnold School of Public Health at the University of South C arolina (USC). Dr. Vena was Professor of Social and Preventive Medicine at the State University

of New York at Buffalo, School of Medicine and Biomedical Sciences and a research fellow at Roswell Park Cancer Institute (1981

- 2003) and Director of the Envir onment & Societ y Institute (1999

- 2003). Dr. Vena received his B.S. in Biology from St. Bonaventure University and his M.S. and Ph.D. degrees in Epidemiology from the State University of New York at Buffalo. Dr. Vena is a Fellow of the American College of Epidemiology and the American Epidemiological Societ y, a member of the International Society for Environmental Epidemiology , Societ y for Epidemiologic Research and the American Public Health Association (APHA). He has published extensively in the field of environmental and occupational epidemiology

with a focus on cancer epidemiology and reproductive and developmental health. Studies have included descriptive and analy tic studies of air and water pollution, bladder cancer and drinking water contaminants, oc cupational exposures, health of municipal workers including firefighters and police officers, diet, electromagnetic fields, persistent environmental toxicants and a Cohort Study

of Sportsmen in the Great Lakes region. Since 1981, Dr. Vena has taught
course s in epidemiologic methods and applications in occupational health and in environmental health and has mentored graduate students, post

- doctoral fellows and junior facult y. **Charles Vorhees**

**, Ph.D.**
Dr. Vorhees has 35 ye ars of experience conducting neuroscience/neurotoxicology and neuroteratology

research. Dr. Vorhees has served on numerous National Institutes of Health site visit committees, special emphasis panels, and ad hoc review committees sinc e 1984, and was a regular member of a study section from 1994

- 1998, serving as interim chair in 1997. He has served on advisory

committees to the US Food and Drug Administration, US Environmental Protection agency , National Research Council, several private foundations, and a number of pharmaceutical companies. Dr. Vorhees was Director of the Graduate Program in Molecular and Developmental Biology , University of Cincinnati College of Medicine, 1998

- 2004.12

**Heather Young**

**, Ph.D., M.P.H.** Dr. Young is an Associate Professor of Epidemiology and Biostatistics at The George Washington University

School of Public Health and Health Services. She has ten y ears of experience in epidemiologic and biostatistical consulting and has taught numerous c ourses in graduate epidemiology

and biostatistics to public health and health professions students. She completed her MPH and PhD in epidemiology at The George Washington University . She currentl y teaches courses in Advanced Data Analysis for Public Heal th, Design of Health Studies, Reproductive and Perinatal Epidemiology, Cancer Epidemiology , and Pesticides and Cancer. Her areas of research interest include cancer particularl y reproductive cancers, environmental and occupational exposure assessment, rep roductive outcomes related to environmental and occupation exposures, pesticide exposure assessment, and health of military and veteran populations. Dr. Young is currently involved in research examining AIDS

- related malignancies in the District of Columbi a, cancer patterns in Gulf War veterans, reproductive outcomes in Army

Chemical Corps Veterans exposed to dioxin during Vietnam, cancer disparities in the District of Columbia, and breast cancer patient navigation in the District of Columbia. In addition, she has served as a technical advisor for data issues for DC’s HIV AIDS Administration and as a statistical consultant on several veterans’ health studies for the Institute of Medicine’s Medical Follow

- Up Agency . She has also published papers examining o varian cancer risk in the Central Valley of California as related to triazine exposure and has extensive knowledge of California’s Pesticide Usage Database. She also serves as a reviewer for numerous epidemiology

and environmental health journals as well as sitting on the Veterans Administration Women Veterans Health Program Center of Excellence Review Panel and has served as an ad hoc member on various EPA FIFRA Scientific Advisory Panels.