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                                                                   EXHIBIT 10.36

                                    AGREEMENT

      THIS AMENDMENT AGREEMENT is made on 7th August 2003 between (1) THE
UNIVERSITY OF WALES COLLEGE OF MEDICINE, formerly the Welsh National School of
Medicine whose principal office is at Heath Park, Cardiff, Wales, CF4 4XN
("COLLEGE"); (2) BIOANALYSIS LIMITED, a company incorporated in England and
Wales whose registered office is at 5, Chiltern Close, Cardiff Industrial Park,
Llanishen, Cardiff, Wales, CF14 5DL with registered number 0934969
("BIOANALYSIS"); and (3) MOLECULAR LIGHT TECHNOLOGY LIMITED, a company
incorporated in England and Wales whose registered office is at 5, Chiltern
Close, Cardiff Industrial Park, Llanishen, Cardiff, Wales, CF14 5DL with
registered number 2339845 ("MLT").

                                     WHEREAS

      A. The College and Bioanalysis have entered into the Bioanalysis Agreement
(as defined below) and the Supplemental Agreement (as defined below).

      B. The College and MLT have entered into the MLT Agreement (as defined
below).

      C. The College and Bioanalysis wish to make certain amendments to the
Bioanalysis Agreement and the College and MLT wish to make certain amendments to
the MLT Agreement to take account of the fact that Bioanalysis and MLT are now
part of the same group of companies.

      THIS DEED WITNESSETH as follows

1.    DEFINITIONS

      1.1   In this Amendment Agreement:

            "AFFILIATE" means, with respect to any person:

              (A) any Connected Person of that person;

              (B) any other person that, directly or indirectly through one or
more intermediaries, controls, is controlled by, or is under common control with
such person and for the purposes of this definition, the term "control" shall
mean the possession, directly or indirectly, of the power to direct or cause the
direction of the management and policies of a person, whether through the
ownership of voting securities, by contract or otherwise; or

              (C) where that person is a partnership, another partner in that
partnership or a linked partnership or fund;

            "AMENDMENT AGREEMENT" means this amendment agreement together with
all schedules and annexures to it, as amended from time to time by written
agreement of all the Parties;



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            "BIOANALYSIS AGREEMENT" means the licence agreement between the
College and Bioanalysis relating to certain technology and intellectual property
assets dated 12 July 1984 as amended;

            "CONNECTED PERSON" means in relation to a company, another company
controlled by the same person or persons connected with him or a person who has
control of that Company on his own or together with persons connected with him
and for the purposes of this definition, the term "control" shall mean the
possession, directly or indirectly, of the power to direct or cause the
direction of the management and policies of a person, whether through the
ownership of voting securities, by contract or otherwise;

            "EARLIER AGREEMENT" means the Bioanalysis Agreement, the
Supplemental Agreement and the MLT Agreement;

            "MLT AGREEMENT" means the licence agreement entered between College
and MLT relating to certain technology and intellectual property assets dated 12
July 1990 as amended;

            "PARTIES" means the parties to this Amendment Agreement and "PARTY"
shall mean any one of them;

            "SUPPLEMENTAL AGREEMENT" means the amendment to the Bioanalysis
Agreement in the form of a supplemental agreement between College and
Bioanalysis dated 12 July 1990.

      1.2 The schedules form part of this Amendment Agreement and shall be
construed and shall have the same full force and effect as if expressly set out
in the body of this Amendment Agreement and any reference to this Amendment
Agreement shall include the schedules.

      1.3 The headings are inserted for convenience only and shall not affect
the construction of this Amendment Agreement.

2.    AMENDMENTS TO BIOANALYSIS AGREEMENT

      2.1 Expressions defined in the Bioanalysis Agreement shall have the same
meaning in this Clause 2 (unless the context otherwise requires or a term is
redefined or amended in this Amendment Agreement).

      2.2 In the amendments set out in this Clause 2 and in the interpretation
of the Bioanalysis Agreement "AFFILIATE" shall have the meaning set out in
Clause 1.1 above of this Amendment Agreement but shall specifically exclude
those parties defined as Affiliates under the terms of the agreement entered
into between Gen-Probe Inc, Bioanalysis and the College dated 21 January 1986,
for as long as such licence granted to Gen-Probe and its Affiliates (as defined
in that agreement dated 21 January 1986) remains in force.



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      2.3 References to page numbers, clauses, sub-clauses and schedules in
Clauses 2.4 to 2.6 shall be construed as references to page numbers, clauses,
sub-clauses and schedules of the Bioanalysis Agreement.

      2.4 The following amendment shall be made to the Bioanalysis Agreement and
will apply with effect from the date of this Amendment Agreement:

            2.4.1 Clause 5 shall be deleted and replaced with the following:

                  Bioanalysis shall:

                  5.1   be entitled to sub-licence to Affiliates and other
                        commercial organisations with a view to the commercial
                        exploitation of the Chemiluminescence Technology covered
                        by the Patents provided that Bioanalysis shall remain
                        responsible for all acts and omissions of such
                        sub-licensees as though they were by Bioanalysis;

                  5.2   other then as permitted under clause 5.1, not assign,
                        transfer, mortgage, charge or part with any of its
                        rights duties or obligations under this Agreement

      2.5 In respect of any sub-licence granted after the date of this Amendment
Agreement, Bioanalysis shall pay to the College in respect of sales of Licensed
Products by Affiliates such royalties, specified in Clause 10 of the Bioanalysis
Agreement, as if sales of Licensed Products by Affiliates had been made by
Bioanalysis.

      2.6 Bioanalysis shall procure the observance of all terms and conditions
of the Bioanalysis Agreement by its Affiliates and other commercial
organisations who are sub-licensed after the date of this Amendment Agreement
pursuant to Clause 5.1 and breach by such Affiliates or other organisations
shall be deemed to be a breach by Bioanalysis of the terms of the Bioanalysis
Agreement. Bioanalysis shall at all times indemnify and keep indemnified the
College against all or any costs, claims, damages or expenses incurred by the
College or for which the College may become liable as a result of the default or
negligence of any Affiliate or other sub-licensee.

      2.7 Bioanalysis warrants to the College that it will not do anything that
will breach the terms of any sub-licences granted by Bioanalysis to third
parties at the date of this Amendment Agreement and Bioanalysis shall at all
times indemnify and keep indemnified the College against all or any costs,
claims, damages or expenses incurred by the College or for which the College may
become liable as a result of breach of this warranty.

3.    AMENDMENTS TO MLT AGREEMENT

      3.1 Expressions defined in the MLT Agreement shall have the same meaning
in this Clause 3 (unless the context otherwise requires or a term is redefined
or amended in this Amendment Agreement).



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      3.2 References to page numbers, clauses, sub-clauses and schedules in
Clauses 3.3 to 3.6 shall be construed as references to page numbers, clauses,
sub-clauses and schedules of the MLT Agreement.

      3.3 The following amendments shall be made to the MLT Agreement and will
apply with effect from the date of this Amendment Agreement:

            3.3.1 Clause 5.6 shall be deleted and replaced with the following

                  5.6   The Licensee shall be entitled to sub-licence any of the
                        rights hereby granted with a view to the commercial
                        exploitation of the Process provided that the Licensee
                        shall remain responsible for all acts and omissions of
                        such sub-licensees as though they were by the Licensee.

      3.4 MLT shall pay to the College in respect of sales of Products by
Affiliates of MLT sub-licensed in accordance with Clause 5.6 such royalties
specified in clause 6.2 of the MLT Agreement, as if sales of Products by
Affiliates had been made by MLT.

      3.5 Without prejudice to Clause 5.6 MLT shall procure the observance of
all terms and conditions of the MLT Agreement by its Affiliates and other
sub-licences sub-licensed pursuant to Clause 5.6 and breach by its Affiliates or
other sub-licences shall be deemed to be a breach by MLT of the MLT Agreement.
MLT shall at all times indemnify and keep indemnified the College against all or
any costs, claims, damages or expenses incurred by the College or for which the
College may become liable as a result of the default or negligence of any
Affiliate or other sub-licensee.

      3.6 MLT warrants to the College that (i) it will not do anything which is
in breach of any of the sub-licences granted by MLT and (ii) MLT shall at all
times indemnify and keep indemnified the College against all or any costs,
claims, damages or expenses incurred by the College or for which the College may
become liable as a result of breach of this warranty.

4.    EXCLUSIVITY / CONSENT

      4.1 The Parties agree that, to the extent that, if any, there is an
overlap between the scope of the rights licensed in the Bioanalysis Agreement
and the rights licensed in the MLT Agreement, they shall be deemed by all of the
Parties not to constitute any breach of either the Bioanalysis Agreement or MLT
Agreement and the College shall have no liability in respect of such overlap.

      4.2 In part consideration of the grant of the additional indemnities set
out in this Amendment Agreement, the College waives its rights, and MLT shall
have no liability under the MLT Agreement (save, for the avoidance of doubt, as
set out in Clause 3 of this Amendment Agreement above), in respect of the
following:

              (A) to give consent in relation to MLT and/or MLT Research
entering into of the sub-licences listed in Schedule A and



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              (B) to receive a copy of such sub-licences.

      4.3 In addition and in part consideration of the grant of the additional
indemnities set out in this Amendment Agreement, the College waives its rights
under the Bioanalysis Agreement,

              (A) to give consent in relation to the entering into of the
sub-licences listed in Schedule A and

              (B) to receive a copy of such sub-licences.

      4.4 The liability of the College shall not be increased by entering into
this Agreement and shall remain as it would have been had this Amendment
Agreement not been entered into.

5.    CONFORMED COPIES

      5.1 Following the execution of this Amendment Agreement the Parties shall,
in respect of the Earlier Agreements to which they are a party, produce and do
all acts necessary to create such copies of Earlier Agreements incorporating the
amendments detailed in this Amendment Agreement as are necessary to comply with
the regulatory filing requirements of the United Kingdom Patent Office or any
other such regulatory authority anywhere in the world. All such acts necessary
by the College shall only be carried out at the express request of either of the
other Parties and such requesting Party shall be responsible for and shall
indemnify the College in respect of all out-of-pocket costs and expenses
(including without limitation legal and other professional costs and expenses)
which the College actually incurs in complying with any such request.

6.    GENERAL

      6.1 Save as expressly amended by this Amendment Agreement, the Bioanalysis
Licence, the Supplemental Agreement and the MLT Licence shall remain in full
force and effect.

      6.2 Nothing in this Amendment Agreement shall operate to give any Party to
this Amendment Agreement rights or obligations under an Earlier Agreement to
which it was not previously a party.

      6.3 No Party shall assign or purport to assign or otherwise deal with any
of its rights and obligations under this Amendment Agreement except with the
express prior written consent of the other Parties, provided that MLT shall be
entitled to assign its right and obligations to any Affiliate.

      6.4 This Amendment Agreement may be executed in any number of
counterparts, all of which taken together shall constitute one and the same
agreement and each Party may enter into this Amendment Agreement by executing a
counterpart.

      6.5 This Amendment Agreement is governed by and shall be construed in
accordance with English law. Each Party submits to the exclusive jurisdiction of
the English courts for all purposes relating to this Amendment Agreement.




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Signed By

/s/ Mike Grant
-----------------------------------
Authorised Signatory for
and on behalf of
THE UNIVERSITY OF WALES
COLLEGE OF MEDICINE

Signed By

/s/ Stuart Woodhead
-----------------------------------
Authorised Signatory for
and on behalf of
BIOANALYSIS LIMITED

Signed By

/s/ Stuart Woodhead
-----------------------------------
Authorised Signatory for
and on behalf of
MOLECULAR LIGHT
TECHNOLOGY LIMITED



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                                   SCHEDULE A

                                  SUB-LICENCES

1.    Agreement between Rhone Diagnostics Technologies Limited ("RDT") and MLT
      Research dated 26 July 1997.

2.    Licence Agreement between MLTR and Biocode Limited ("Biocode") dated 8
      February 2000.

3.    Evaluation Agreement between MLT Research and Minton, Treharne & Davies
      Ltd ("MTD") dated 24 September 1999.

4.    Agreement between Molecular Light Technology Research Ltd and Cardiff
      University dated 10 November 1999.

5.    Agreement between Molecular Light Technology Research Limited and the
      Nottingham Trent University dated 3 November 1997, together with letter
      from Stuart Woodhead to Dr Ellen Billett dated 27 August 1999.

6.    Agreement between Molecular Light Technology Research Limited and
      University of Wales, Cardiff dated 9 January 1998.

7.    Agreement between Molecular Light Technology Research Limited and Cardiff
      University dated 28 May 2001.

8.    Development Agreement between Molecular Light Technology Research Limited
      and Shell International Chemicals B.V. dated 15 December 1998.

9.    Evaluation Agreement between Molecular Light Technology Research Limited
      and Shell Research Limited dated 28 October 1998 as amended by an
      Evaluation Amendment dated 29 March 1999.

10.   Agreement between Cardiff University and Molecular Light Technology
      Research Limited dated 1 October 1999.

11.   Evaluation Agreement between Molecular Light Technology Research Limited
      and University of Exeter dated 29 June 2001.

12.   Agreement between Molecular Light Technology Research Limited and the
      University of Exeter dated 9 August 2001.

13.   Agreement between MLT and Molecular Light Technology Research Limited
      dated 2003




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