<PAGE>
EXHIBIT 10.1

                             SUBSCRIPTION AGREEMENT


         THIS SUBSCRIPTION AGREEMENT (this "AGREEMENT"), dated as of January 20,
2004, is entered into by and between AETHLON MEDICAL, INC., a Nevada corporation
(the "COMPANY"), and the Lion Share Group, Inc., (the "Investor") a corporation
organized under the laws of the Bahamas.

                                    RECITALS:

         The Investor would like to purchase from the Company, and the Company
would like to sell to the Investor, certain shares of the Common Stock, par
value $0.001 per share of the Company ("COMMON STOCK"), on the terms and subject
to the conditions set forth in this Agreement.

                                   AGREEMENT:

         NOW, THEREFORE, in consideration of the mutual covenants and agreements
herein contained, the receipt and sufficiency of which are agreed upon by the
parties, the parties hereto hereby agree as follows:

         SECTION 1.  PURCHASES AND SALES OF COMMON STOCK.

         (a) Upon the terms and subject to the conditions set forth herein, the
Company shall sell to the Investor, and the Investor shall purchase from the
Company, an aggregate of 5,000,000 shares of Common Stock. The purchases and
sales of shares of Common Stock pursuant to this Agreement shall occur at an
aggregate of three (3) installment closings (each, an "INSTALLMENT CLOSING"), in
the respective share amounts, at the respective per share purchase prices, at
the respective aggregate purchase price amounts, and on the respective dates set
forth on the schedule attached hereto as EXHIBIT A (the "SCHEDULE OF INSTALLMENT
CLOSINGS"). The shares of Common Stock to be purchased by the Investor from the
Company at the Installment Closings pursuant to this Agreement as sometimes
referred to herein as the "PURCHASED SHARES".

         (b) Each Installment Closing shall take place at 10:00 am (Pacific
local time) on the date set forth on the Schedule of Installment Closings (each
such date, an "INSTALLMENT CLOSING DATE"), by payment by the Investor to the
Company of the aggregate purchase price for the shares of Common Stock to be
purchased in such Installment Closing (as set forth on the Schedule of
Installment Closings), in cash by wire transfer of immediately available funds
(denominated in U.S. dollars) to the Company's account (with respect to each
Installment Closing, THE "PURCHASE PRICE"), in exchange for issuance by the
Company to the Investor of the shares of Common Stock purchased by the Investor
from the Company in such Installment Closing.

         (c) Upon execution and delivery of this Agreement, as collateral for
the obligation of Investor to consummate the Installment Closings hereunder, the
Investor shall deliver to the Company a letter of credit, in form and substance
reasonably acceptable to the Company (the "LETTER OF CREDIT"), along with any
authorizations deemed necessary or advisable by the Company to allow the Company
to draw down on the Letter of Credit in accordance with the terms and conditions
of this Agreement. In the event of a failure by the Investor to pay the
aggregate Purchase Price with respect to one or more Installment Closings, the
Company may (but is not required to) draw down upon the Letter of Credit in an
amount equal to the aggregate Purchase Price with respect to such Installment
Closing.

         (d) The Investor's obligation to consummate each Installment Closing
shall be conditioned upon: (i) receipt by the Investor of evidence that a stock
certificate representing the shares of Common Stock purchased by the Investor
from the Company at such Installment Closing has been issued to the Investor;
(ii) all of the representations and warranties of the Company set forth in this
Agreement being true and correct as of the applicable Installment Closing Date;
and (iii) the Company not being in material breach of this Agreement as of the
applicable Installment Closing Dat/e. The Company's obligation to consummate
each Installment Closing shall be conditioned upon: (i) receipt by the Company
of the aggregate Purchase Price with respect to such Installment Closing; (ii)
all of the representations and warranties of the Investor set forth in this
Agreement being true and correct as of the applicable Installment Closing Date;
and (iii) the Investor not being in material breach of this Agreement as of the
applicable Installment Closing Date.

                                      -1-
<PAGE>

         SECTION 2. REPRESENTATIONS AND WARRANTIES OF THE COMPANY TO THE
INVESTOR.

         The Company hereby represents and warrants to the Investor, as of the
date of this Agreement and as of each Installment Closing Date, as follows:

         (a) ORGANIZATION. The Company is a corporation duly organized, validly
existing and in good standing under the laws of State of Nevada and has all
requisite corporate power and authority to own and lease its property and to
carry on its business as presently conducted.

         (b) AUTHORIZATION OF AGREEMENT AND ISSUANCE OF THE PURCHASED SHARES;
ENFORCEABILITY; Non-Contravention. The execution, delivery and performance by
the Company of this Agreement and issuance of the Purchased Shares have been
duly authorized by all requisite action on the part of the Company. This
Agreement has been duly executed and delivered by the Company and constitutes a
valid and binding obligation of the Company, enforceable in accordance with its
respective terms. The execution, delivery and performance of this Agreement, and
the compliance with the provisions hereof and thereof by the Company, will not:

                  (i) materially violate any provision of law, statute,
ordinance, rule or regulation or any ruling, writ, injunction, order, judgment
or decree of any court, administrative agency or other governmental body;

                  (ii) materially conflict with or result in any material breach
of any of the terms, conditions or provisions of, or constitute (with due notice
or lapse of time, or both) a material default (or give rise to any right of
termination, cancellation or acceleration) under (A) any agreement, document,
instrument, contract, understanding, arrangement, note, indenture, mortgage or
lease to which the Company is a party or under which the Company or any of its
assets is bound or affected, (B) the Company's Certificate of Incorporation, or
(C) the Company's By-laws; or

                  (iii) result in the creation of any lien, security interest,
charge or encumbrance upon any of the properties or assets of the Company.

         (c) CONSENTS AND APPROVALS. No authorization, consent, approval or
other order of, or declaration to or filing with, any governmental agency or
body (other than filings required to be made under applicable federal and state
securities laws) is required for the valid authorization, execution, delivery
and performance by the Company of this Agreement or the issuance of the
Purchased Shares that has not been obtained or made, except for the filing of
Form D with the U.S. Securities and Exchange Commission (the "Commission") and
such filings as are required to be made under applicable Federal and state
securities laws. The Company has obtained all other consents that are necessary
to permit the consummation of the transactions contemplated hereby.

         (d) SECURITIES LAWS. Based on the representations of the Investor set
forth in SECTION 3 of this Agreement, the offer, sale and issuance of the
Purchased Shares to the Investor hereunder, are exempt from the registration
requirements of the United States Securities Act of 1933, as amended (the
"SECURITIES ACT").

                                      -2-
<PAGE>

         SECTION 3. REPRESENTATIONS AND WARRANTIES OF THE INVESTOR TO THE
COMPANY.

         The Investor represents and warrants to the Company, as of the date of
this Agreement and as of each Installment Closing Date, as follows:

         (a) The execution, delivery and performance by the Investor of this
Agreement and issuance of the Purchased Shares have been duly authorized by all
requisite action on the part of the Investor. This Agreement has been duly
executed and delivered by the Investor and constitutes a valid and binding
obligation of the Investor, enforceable in accordance with its respective terms.
The execution, delivery and performance of this Agreement, and the compliance
with the provisions hereof and thereof by the Investor, will not:

                  (i) materially violate any provision of law, statute,
         ordinance, rule or regulation or any ruling, writ, injunction, order,
         judgment or decree of any court, administrative agency or other
         governmental body;

                  (ii) materially conflict with or result in any material breach
         of any of the terms, conditions or provisions of, or constitute (with
         due notice or lapse of time, or both) a material default (or give rise
         to any right of termination, cancellation or acceleration) under any
         agreement, document, instrument, contract, understanding, arrangement,
         note, indenture, mortgage or lease to which the Investor is a party or
         under which the Investor or any of its assets are bound or affected or
         conflict with any organizational or other governing document of the
         Investor; or

                  (iii) result in the creation of any lien, security interest,
         charge or encumbrance upon any of the properties or assets of the
         Investor.

         (b) The Investor understands and acknowledges that the offering and
sale of the Purchased Shares pursuant to this Agreement is intended to be exempt
from registration under the Securities Act, and from qualification under any
applicable state securities law by virtue of Section 4(2) of the Securities Act
and Rule 506 of Regulation D thereunder, on the ground, among others, that no
distribution or public offering of Purchased Shares is to be effected and the
Purchased Shares will be issued by the Company in connection with a transaction
that does not involve any public offering within the meaning of Section 4(2) of
the Securities Act, the rules and regulations of the United States Securities
and Exchange Commission thereunder, or any comparable provision of applicable
securities laws or the rules and regulations of the regulatory authorities
thereunder.

         (c) The Investor will acquire the Purchased Shares for investment for
the account of the Investor and not for the account of any other person or
entity of any kind, and not with a view toward resale or other distribution
thereof. The Investor understands that the Purchased Shares have not been
registered under the Securities Act and applicable United States state
securities laws and, therefore, cannot be resold unless they are subsequently
registered under the Securities Act and applicable United States state
securities laws or unless an exemption from such registration is available.
Investor is acquiring the Purchased Shares hereunder in the ordinary course of
its business. Investor does not have any agreement or understanding, directly or
indirectly, with any person or entity of any kind to distribute any of the
Purchased Shares. The Investor further understands and agrees that, until so
registered or transferred pursuant to the provisions of Rule 144 under the
Securities Act, the certificate(s) for the Purchased Shares shall bear a legend,
prominently stamped or printed thereon, reading substantially as follows:

         THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF
         1933, AS AMENDED (THE "SECURITIES ACT"), OR APPLICABLE STATE SECURITIES
         LAWS. THESE SECURITIES HAVE BEEN ACQUIRED FOR INVESTMENT AND NOT WITH A
         VIEW TO THEIR DISTRIBUTION OR RESALE, AND MAY NOT BE SOLD, PLEDGED, OR
         OTHERWISE TRANSFERRED WITHOUT AN EFFECTIVE REGISTRATION STATEMENT FOR
         SUCH SECURITIES UNDER THE SECURITIES ACT AND APPLICABLE STATE
         SECURITIES LAWS, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY
         TO THE EFFECT THAT SUCH REGISTRATION IS NOT REQUIRED.


                                       3-
<PAGE>

         (d) The Investor, during the course of this transaction and prior to
the purchase of the Purchased Shares, has had the opportunity to ask questions
of and receive answers from representatives of the Company concerning the terms
and conditions of the offering, and to obtain any additional information or
documents relative to the Company, its business and an investment, as the
Investor has deemed necessary. The Investor agrees and acknowledges, however,
that it has not been furnished any offering literature or prospectus concerning
the Company other than this Agreement and, in making its decision to acquire the
Purchased Shares hereunder, the Investor has relied solely upon this Agreement
and independent investigations made by the Investor. The Investor acknowledges
that no representations or warranties have been made to the Investor by the
Company, or any officer, employee, agent or affiliate of the Company, except as
contained in this Agreement.

         (e) The Investor understands that the offering of Purchased Shares
pursuant to this Agreement is limited solely to "accredited investors," as that
term is defined in Regulation D under the Securities Act. The Investor
represents and warrants to the Company that the Investor is an "accredited
investor", as so defined, by virtue of the Investor meeting the criteria checked
by the Investor on the signature page hereto, and that the Investor's principal
place of business is as listed on the signature page hereto.

         (f) The Investor has the capacity to protect its own interests in
connection with the purchase of the Purchased Shares. The purchase of the
Purchased Shares by the Investor is consistent with its general investment
objectives and the Investor understands that the purchase of the Purchased
Shares is a speculative investment that involves a high degree of risk. The
Investor can bear the economic risks of this investment and can afford a
complete loss of its investment in the Purchased Shares. The Investor
understands that there is no established market for the Company's capital stock
(including, without limitation, Common Stock) and there is no assurance that any
public market for such stock will develop. The Investor has no present need for
liquidity in connection with its purchase of the Purchased Shares.

         (g) The Investor understands and acknowledges that the Purchased Shares
are "restricted securities" under United States securities laws and any
purported transfer of the Purchased Shares in violation of applicable law is
null and void. The Investor understands and acknowledges that the Company may,
at its discretion, refuse to register on its share transfer books any purported
transferee of the Purchased Shares in the event of an attempted transfer thereof
in violation of applicable law.

         (h) If the Investor is a nonresident alien individual, corporation,
partnership, limited liability company, trust, estate or other entity, it is not
a U.S. person (as those terms are defined in the Internal Revenue Code of 1986,
as amended (the "INTERNAL REVENUE CODE"), and the United States Treasury
Regulations promulgated thereunder), and it acknowledges that the Company is
required, as a withholding agent, to withhold U.S. taxes and/or backup
withholding with respect to dividends and other distributions paid with respect
to the Purchased Shares in accordance with the applicable provisions of the
Internal Revenue Code and Treasury Regulations, unless (x) an exemption from
such withholding is available, (y) the Investor provides to the Company in a
timely manner duly completed documentation evidencing qualification for such
exemption, and (z) the Company determines, in its sole discretion, that the
Company may rely on such documentation for this purpose. The Investor has
provided to the Company a duly completed Internal Revenue Service ("IRS") Form
W-8BEN (Certificate of Foreign Status of Beneficial Owner for United States Tax
Withholding) and agrees to provide to the Company, in a timely manner, such
other duly completed documentation as the Company may request (including any
applicable alternative IRS Forms if Form W-8BEN is inapplicable to the Investor
and such duly completed updated IRS forms and other documentation as the Company
may request from time to time), all of which documentation must be in form and
substance satisfactory to the Company;


                                      -4-
<PAGE>

         SECTION 4. INDEMNIFICATION. The Investor agrees to indemnify and hold
harmless the Company and its affiliates, agents, representatives, employees,
directors, officers and stockholders from and against any and all loss,
liability, claim, damage and expense whatsoever (including, but not limited to,
any and all expenses reasonably incurred in investigating, preparing or
defending against any litigation commenced or threatened or any claim
whatsoever) arising out of or based upon: (a) any false representation and
warranty of the Investor contained in this Agreement or any breach or failure by
the Investor to comply with any covenant and/or agreement made by the Investor
herein; or (b) any transfer of the Purchased Shares contrary to such
representations and warranties or covenants and agreements.

         SECTION 5. TERMINATION. Either party may terminate this Agreement upon
material breach of this Agreement by the other party that has not been cured in
its entirety within fifteen (15) business days after written notice thereof has
been provided to the breaching party. The parties agree that a party's failure
to consummate the Installment Closings in accordance with the terms and
conditions of this Agreement constitute a material breach by such party of this
Agreement.

         SECTION 6.  GENERAL PROVISIONS.

         (a) REMEDIES. In case any one or more of the covenants and/or
agreements set forth in this Agreement shall have been breached by any party
hereto, the party entitled to the benefit of such covenants or agreements may
proceed to protect and enforce their rights either by suit in equity and/or
action at law, including, but not limited to, an action for damages as a result
of any such breach and/or an action for specific performance of any such
covenant or agreement contained in this Agreement. The rights, powers and
remedies of the parties under this Agreement are cumulative and not exclusive of
any other right, power or remedy which such parties may have under any other
agreement or law. No single or partial assertion or exercise of any right, power
or remedy of a party hereunder shall preclude any other or further assertion or
exercise thereof.

         (b) SUCCESSORS AND ASSIGNS. Except as otherwise expressly provided
herein, this Agreement shall bind and inure to the benefit of the Company and
the Investor and their respective permitted successors and assigns. This
Agreement may not be assigned by either party without the prior written consent
of the other party.

         (c) ENTIRE AGREEMENT. This Agreement (including any schedules and
exhibits hereto) contains the entire agreement among the parties with respect to
the subject matter hereof and supersedes all prior and contemporaneous
arrangements or understandings, whether written or oral, with respect thereto.

         (d) CHANGES. The terms and provisions of this Agreement may not be
modified or amended, or any of the provisions hereof waived, temporarily or
permanently, except pursuant to a writing executed by duly authorized
representatives of the Company and the Investor.

         (e) COUNTERPARTS. This Agreement may be executed in any number of
counterparts and by the different parties on separate counterparts each of
which, when so executed and delivered, shall be an original but all of which
together shall constitute one and the same instrument.

         (f) SEVERABILITY. Any provision of this Agreement that is prohibited or
unenforceable in any jurisdiction shall, as to such jurisdiction, be ineffective
to the extent of such prohibition or unenforceability without invalidating the
remaining provisions hereof, and any such prohibition or unenforceability in any
jurisdiction shall not invalidate or render unenforceable such provision in any
other jurisdiction.

         (g) GOVERNING LAW; VENUE; JURISDICTION. The corporate law of the State
of Nevada will govern all questions concerning the relative rights of the
Company and the holders of its securities (including, without limitation, the
Purchased Shares). All other questions concerning the construction, validity and
interpretation of this Agreement will be governed by and construed in accordance
with the internal laws of the State of Maryland, without giving effect to any
choice of law or conflict of law provision or rule (whether of the State of


                                      -5-
<PAGE>

Maryland or any other jurisdiction) that would cause the application of the laws
of any jurisdiction other than the State of Maryland. The parties each agree
that venue for any dispute arising under this Agreement shall be proper in any
state court located in Montgomery County in the State of Maryland or in the
United States District Court for the District of Maryland (if a basis for
federal jurisdiction exists) and each party hereby irrevocably waives any right
to object to the maintenance of a suit in such courts on the basis of improper
venue or of inconvenience of forum. Each party irrevocably consents to the
non-exclusive jurisdiction of any state court located in Montgomery County in
the State of Maryland or in the United States District Court for the District of
Maryland (if a basis for federal jurisdiction exists).

         (h) WAIVER OF JURY TRIAL. The parties to this Agreement each hereby
irrevocably waives, to the fullest extent permitted by law, any right to trial
by jury of any claim, demand, action or cause of action arising under this
Agreement, whether now existing or hereafter arising, and whether in contract,
tort, equity, or otherwise. The parties to this Agreement each hereby
irrevocably agrees and consents that any such claim, demand, action or cause of
action shall be decided by court trial without a jury and that the parties to
this Agreement may file an original counterpart of a copy of this Agreement with
any court as written evidence of the consent of the parties hereto to the waiver
of their right to trial by jury.

         (i) NOTICES. Any and all notices or other communications or deliveries
required or permitted to be provided hereunder shall be in writing and shall be
deemed given and effective on the earliest of (i) the date of transmission, if
such notice or communication is delivered via facsimile at the facsimile number
set forth on the signature pages attached hereto prior to 5:00 p.m. (Pacific
local time) on a business day, (ii) the next business day after the date of
transmission, if such notice or communication is delivered via facsimile at the
facsimile number set forth on the signature pages attached hereto on a day that
is not a business day or later than 5:00 p.m. (Pacific local time) on any
business day, (iii) the second business day following the date of mailing, if
sent by U.S. nationally recognized overnight courier service, or (iv) upon
actual receipt by the party to whom such notice is required to be given. The
address for such notices and communications shall be as set forth on the
signature pages attached hereto.

                                    * * * * *

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the date first above written.


                                         THE COMPANY:

                                         AETHLON MEDICAL, INC.

                                         By: s/ James A. Joyce
                                         Name: James A. Joyce
                                         Title: Chairman, President and CEO

                                         ADDRESS:

                                         AETHLON MEDICAL, INC.
                                         7825 FAY AVENUE, SUITE 200,
                                         LA JOLLA, CALIFORNIA
                                         USA

                                         THE INVESTOR:

                                         [See Attached Signature Page]


                                      -6-
<PAGE>



                                SIGNATURE PAGE TO
                             SUBSCRIPTION AGREEMENT

By execution of this Signature Page, the Investor agrees to be bound by the
provisions of this Agreement and authorizes the Company to append this Signature
Page to a counterpart of the Agreement as evidence thereof. Pursuant to SECTION
3(E) of the Agreement, the undersigned represents and warrants that the Investor
is an "accredited investor" (as such term is defined in Regulation D under the
Securities Act) by reason of the qualifications described opposite the checked
box(es) set forth below.

[SIGNATURE BLOCK]

LION SHARE GROUP, INC.

By: s/ Hubert L. Pinder
Printed Name: Hubert L. Pinder
Title:President

Address:
20 Madeira Street
P.O. Box N 1315
Nassau, BAHAMAS
Telephone No: 242-324-3164 Or 242-457-3270 Fax No. 242-324-4042

THE INVESTOR IS AN "ACCREDITED INVESTOR" BY VIRTUE OF THE INVESTOR BEING:


_____    (1) a natural person (not an entity) whose individual net worth, or
         joint net worth with his or her spouse, exceeds one million dollars
         ($1,000,000);

_____    (2) a natural person (not an entity) who had individual income in
         excess of two hundred thousand dollars ($200,000) in each of 2001 and
         2002 and has a reasonable expectation of having individual income in
         excess of two hundred thousand dollars ($200,000) in 2003;


_____    (3) a natural person (not an entity) who had joint income with his or
         her spouse in excess of three hundred thousand dollars ($300,000) in
         each of 2001 and 2002 and has a reasonable expectation of having a
         joint income with his or her spouse in excess of three hundred thousand
         dollars ($300,000) in 2003;

X        (4) a trust, with total assets in excess of five million dollars
         ($5,000,000), not formed for the specific purpose of acquiring the
         Purchased Shares, which is directed by a person who has such knowledge
         and experience in financial and business matters that he or she is
         capable of evaluating the merits and risks of an investment in Company;


         (5) a corporation, Massachusetts or similar business trust, or a
         partnership, each with total assets in excess of five million dollars
         ($5,000,000), which was not formed for the specific purpose of
         acquiring the Purchased Shares; or


X        (6) any entity in which all of the equity owners meet at least one of
         the criteria set forth in categories (1) through (5), above.


                                       -7-

<PAGE>

<TABLE>

                                           EXHIBIT A:
                                           ----------

                                Schedule of Installment Closings

                                                                   PER SHARE       AGGREGATE
                                                                PURCHASE PRICE   PURCHASE PRICE
                                                                   OF SHARES       OF SHARES
                                             NUMBER OF SHARES     PURCHASED AT    PURCHASED AT
     INSTALLMENT              DATE OF          PURCHASED AT       INSTALLMENT     INSTALLMENT
       CLOSING               INSTALLMENT        INSTALLMENT        CLOSING          CLOSING
        NUMBER                CLOSING             CLOSING        (US DOLLARS)     (US DOLLARS)
------------------------  -----------------  ----------------  ----------------  --------------
<S>                       <C>                    <C>                 <C>            <C>
Installment Closing #1    February 28, 2004      2,000,000           $0.25          $500,000
------------------------  -----------------  ----------------  ----------------  --------------

Installment Closing #2    March 25, 2004         1,000,000           $0.25          $250,000
------------------------  -----------------  ----------------  ----------------  --------------

Installment Closing #3    June 21,2004           2,000,000           $0.50        $1,000,000
------------------------  -----------------  ----------------  ----------------  --------------

TOTALS:                                          5,000,000             ---        $1,750,000
------------------------  -----------------  ----------------  ----------------  --------------






                                       -8-

</TABLE>