# Support Documents for

Significant New Use Rule (SNUR) on

Premanufacture Notice (PMN)

P-10-222

EPA Docket EPA

- HQ

- OPPT -2011-0577

# Index

A-001 Structure Activity Team (SAT) Report for

PMN P-10-222

A-002 Initial Review Engineering Report for

PMN P-10-222

A-003 Initial Review Exposure Report for

PMN P-10-222

# A-001

Structure Activity Team (SAT) Report

for PMN P-10-222

# A-002

Initial Review Engineering Report

for PMN P-10-222INITIAL REVIEW ENGINEERING REPORT

PMN: 10-0222

Focus Ready Draft 3/8/2010 **Revised 4/26/2010 & 5/20/2010**

ENGINEER: Arnold \ DGR

PV (kg/yr):

SUBMITTER:

USE:

OTHER USES:

MSDS: Yes Label: No

Gen Eqpt: protective gloves/ protective, impervious

clothing/ chemical goggles/ adequate ventilation

Respirator: If engineering controls do not maintain

airborne concentrations below recommended exposure limits

(where applicable) or to an acceptable level (in

countries where exposure limits have not been

established), an approved respirator must be worn.

Health Effects: Causes eye irritation/ may cause

irritation to the respiratory system/ may be harmful if

absorbed through skin/ may be harmful if swallowed

TLV/PEL:

None established for PMN chemical

CRSS :

Chemical Name:

S-H20: 1.1 g/L @ 25.00

VP:

MW:

Physical State and Misc CRSS Info:

Neat: Liquid

Consumer Use: NoSAT (concerns) (03/02/2010):

Migration to groundwater: Moderate

PBT rating: P2B1T2

Drinking Water, Inhalation,

o water with a CC = 22 ppb),

OCCUPATIONAL EXPOSURE RATING: 2A

NOTES & KEY ASSUMPTIONS:

Generated by the 06/07/2005 version of ChemSTEER.

POLLUTION PREVENTION CONSIDERATIONS:

None.

EXPOSURE-BASED REVIEW:INITIAL REVIEW ENGINEERING REPORT

PMN: 10-0222

Manufacturing: Batch

Number of Sites/ Location:

Days/yr:

Basis:

Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note: The daily releases listed for any source below

may coincide with daily releases from the other sources

to the same medium.

Conservative:

t

from:

basis:

Typical:

Worst Cas

to:

from:

basis:Output 2:

to:

from:

basis:

RELEASE TOTAL

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes:

Basis:

Inhalation:

Exposure

Typical:

Worst Cas

Number of wo tes) with inhalation exposure:

Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? Yes

OR

b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Exposure

Typical:

Worst Case

Number of wo tes) with inhalation exposure:

Basis:

INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

OR

b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Dermal:Exposure t

High End:

Number of sites) with dermal exposure:

Basis:

Exposure t

High End:

Number of w sites) with dermal exposure:

Basis:INITIAL REVIEW ENGINEERING REPORT

PMN: 10-0222

Use:

Number of Sites/ Location:

Days/yr:

Basis:

Process Description:

ENVIRONMENTAL RELEASES ESTIMATE SUMMARY

IRER Note:

Output 2:

to:

from:

basis:

RELEASE TOTAL

OCCUPATIONAL EXPOSURES ESTIMATE SUMMARY

Tot. # of workers exposed via assessed routes:

Basis:

Inhalation:

Exposure

Typical:

Worst Cas

Number o on

Basis:INHALATION MONITORING DATA REVIEW

1) Uncertainty (estimate based on model, regulatory limit

or data not specific to industry): Yes

2)a) Exposure level > 1 mg/day? No

OR

b) Hazard Rating for health of 2 or greater? 2 Yes

Inhalation Monitoring Data Desired? Yes (both criteria

met)

Dermal:

Exposure t

High End:

Number of sites) with dermal exposure:

Basis:CALL BY: Dan Roper

Organization: ERG, for EPA/OPPT/CEB

CALL TO:

Organization:

Date: 03/03/2010

Time: 11:32 am

Phone:

PMN: 10-0222

# A-003

Initial Review Exposure Report

for PMN P-10-222