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                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | Pharmacy UpdateJuly/August 1997
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|In This Issue

         *Welcome, New Medical Staff Fellows
                *A Few Facts
                 *Clinical Pharmacy Specialists
                *Pharmacy ResidencyAppointments 1997 - 1998*Restricted Medications

         Pharmacy Update Archives
                Drug Information
         Service

         Pharmacy Department
         Warren G. Magnuson Clinical Center
         National Institutes of Health
         Bethesda, Maryland 20892-1196

         Charles E. Daniels,
         Ph.D.
         Chief, Pharmacy Department

         Editor-in-Chief

         Karim Anton Calis, Pharm.D., M.P.H.
         Coordinator, Drug Information Service, and Endocrinology
         Clinical Pharmacy Specialist[email protected]

         Associate
         Editor

         Amy M. Heck, Pharm.D.

         Specialized Resident in Drug Information Practice and
         Pharmacotherapy[email protected]
         Archives | Welcome, New Medical Staff Fellows

         The pharmacy staff welcomes you and would like to introduce you to 
         the variety of services we offer in support of patient care and biomedical 
         research.

         Inpatient Pharmacy
         The inpatient pharmacy provides medications 
         for hospitalized patients. All medication orders are reviewed 
         by pharmacists before dispensing to the nursing units. Using 
         the patient's medication profile, pharmacists review orders 
         for allergies, appropriateness of dose and dosing interval, 
         drug interactions, and drug incompatibilities. The unit dose 
         staff prepares medications for patient use, each dosage form 
         having been individually packaged and labeled. Parenteral 
         preparations, including injectable investigational drugs, 
         are prepared under rigorous standards for sterility and 
         quality control by the Intravenous Admixture Unit staff or 
         by the Oncology Satellite. Inpatient services are available 
         on a 24-hour basis from the central pharmacy.

         Clinical Pharmacy Services
         Pharmacists with advanced clinical training and experience are assigned 
         to critical care, endocrinology, gastroenterology, neurology, 
         ambulatory care, mental health, oncology, bone marrow transplantation, 
         allergy, and infectious diseases. Their functions include providing 
         patient-speci�c drug-use advice, participating in drug selection, 
         monitoring patient response to therapy, serving as IRB members, 
         counseling patients, and participating in experimental drug protocol 
         design and implementation.

         Drug Information Service
         The Drug Information Service is available to assist clinicians with 
         routine and complex pharmacotherapeutic questions and case consultations. 
         The NIH Drug Information Service (DIS) is equipped with information resources 
         including texts, journals, abstracting services, and online and CD-ROM drug 
         information data bases. The DIS is also responsible for evaluating and monitoring 
         adverse drug reactions reported by healthcare personnel.Additionally, the DIS is the principal resource to the Pharmacy and 
         Therapeutics Committee for evaluating medications, biologicals, and 
         drug-delivery systems, and reviewing and developing medication-related 
         policies and procedures. The DIS also provides assistance with study 
         design, protocol development, and critical literature evaluation.

         Procurement and Control
         The quality control and purchasing of drugs dispensed for patient care 
         are the responsibilities of the Pharmaceutical Procurement and Control 
         Section. This unit purchases all drugs and pharmaceutical supplies 
         authorized for use at the Clinical Center and maintains the formulary 
         of approved drugs.
         
         Pharmaceutical Development
         The Pharmaceutical Development Section (PDS) provides research-related 
         functions as follows: 1) registration and control of all investigational 
         drugs used for patients, 2) formulation of unique dosage forms of both 
         commercially available and investigational drugs, 3) assaying investigational 
         drugs and providing summaries of these data to support the submission 
         of investigational new drug (IND) applications, 4) conducting quality 
         control and stability studies for all products manufactured by the Department, 
         5) aiding investigators in designing blinded studies, and 6) providing 
         information on investigational drugs. Investigational drugs must be 
         registered with PDS before they are administered to Clinical Center patients.
         
         Clinical Pharmacokinetics
         The Clinical Pharmacokinetics Research Laboratory (CPRL) of PDS assists 
         clinical investigators in the design, analysis, and interpretation of 
         pharmacokinetic studies. The CPRL supports physicians in several major 
         areas of pharmacokinetics research including modelling of drugs and/or 
         metabolites, examination of concentration-effect relationships, drug 
         interaction studies, and characterization of drugs with nonlinear disposition. 
         In addition, the CPRL provides consultations on individual patients 
         regarding pharmacokinetic aspects of drug therapy.
         
         Charles E. Daniels, Ph.D.
                                                Chief, Pharmacy Department                                                                                                                                                                                                                                                                                                                                                                                              
|Up to Top                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | A Few Facts

        Outpatient, Discharge, and On Pass Prescriptions
         Physicians should enter any discharge or on pass medications for their patients into MIS 
         the day before the event, or during the morning hours on weekends and holidays. 
         Outpatient prescriptions, discharge medication orders, and prescriptions for 
         patients on pass will be filled only during the Outpatient Pharmacy's scheduled 
         hours of operation.
         
         Prescribing Restricted Antimicrobials
        When prescribing restricted anti-microbials from the MED INDEX in MIS, 
        the following message will appear:
        
                You have selected a restricted antimicrobial. The Pharmacy Department 
                will not act on this order until it is approved by an ID consultant 
                via a telephone call to the Pharmacy.Prescribers are obliged to...*
                Complete the order in MIS*
                Contact the ID Fellow directly or through the Clinical Center Page Operator (496-1211)*
                If the ID fellow is unavailable or does not respond, the prescriber should 
                contact the assigned ID attending physician (page operators have the current 
                coverage schedule).
         
         NoteThe Pharmacy will not dispense a first dose of a restricted antimicrobial without ID approval.Orders for restricted antimicrobials included as adjunctive therapy in NIH studies must 
                be entered into MIS by physicians authorized to prescribe restricted agents for their 
                patients. Otherwise, ID approval is required.Although ID approval may have been granted for a restricted antimicrobial 
                during a patient's prior admission, retreatment with the same restricted 
                antimicrobial is contingent upon ID reapproval.The following antimicrobials have been designated as restricted:*
                ceftazidime*
                cidofovir*
                ciprofloxacin (oral and IV formulations)*
                fluconazole (IV formulation only)*
                foscarnet*
                ganciclovir (oral and IV formulations)*
                imipenem/cilastatin (Primaxin®)*
                itraconazole*
                vancomycin (oral formulation only)
        
        Scheduled (CII) Drugs
         All "TAKE HOME" orders for schedule II drugs for outpatients require that 
         an order signed by the prescribing physician must be sent to the outpatient 
         pharmacy before the medication can be dispensed to patients.
         
         Prescription Blanks
         Physicians should enter any discharge or on pass medications for their patients into MIS 
         the day before the event, or during the morning hours on weekends and holidays. 
         Outpatient prescriptions, discharge medication orders, and prescriptions for 
         patients on pass will be filled only during the Outpatient Pharmacy's scheduled 
         hours of operation.        
         
         Total Parenteral Nutrition:
         All orders for parenteral nutrition (TPN) received in the Pharmacy Department by 
         2 p.m. will be delivered to the patient care unit by 6 p.m. Orders for outpatients 
         or patients who will be discharged on TPN should be entered before 11 a.m. so they 
         can be ready for pick-up after 3 p.m.
         
         Physician's DEA Registration
         Section 1301.25 of the Federal Controlled Substance Act Regulations 
         provide that all physician practitioners employed by the Public Health 
         Service may use their service number (i.e., Social Security number) 
         and branch of service or service agency on all prescriptions issued 
         in lieu of a DEA registration number (Note: you do not need to provide 
         your Social Security number for controlled substances �lled by the 
         Clinical Center Outpatient Pharmacy). For additional information, 
         contact a pharmacist in the Main Pharmacy's Procurement Section 
         (496-9358) or write or telephone:
         
                        Registration Board Drug Enforcement Agency
                        P. O. Box 28033
                        Central Station
                        Washington, DC 20005
                        Telephone (202) 307-7255
                        
                        Pharmacy Phone Numbers
                        Drug Information Service
                                        496-2407Intravenous Admixture Unit
                                        496-6551Office of the Chief
                                        496-4363Oncology Satellite
                                        496-8092Outpatient Pharmacy
                                        496-2866Pharmaceutical Development Section (PDS)
                                        496-1031Pharmaceutical Procurement and Control
                                        496-9358Unit Dose Distribution Unit
                                        496-1914 | Drug Information Service       
|Drug Information Service                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | 496-2407                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Intravenous Admixture Unit                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | 496-6551                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Office of the Chief                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | 496-4363                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Oncology Satellite                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         | 496-8092                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Outpatient Pharmacy                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | 496-2866                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Pharmaceutical Development Section (PDS)                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | 496-1031                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Pharmaceutical Procurement and Control                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     | 496-9358                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Unit Dose Distribution Unit                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                | 496-1914                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             
|Up to Top                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | Clinical Pharmacy SpecialistsPaul Jarosinski, P.D.
                                        NCI / Pediatric Oncology
                                        104-2220-7Barry Goldspiel, Pharm.D.
                                        NCI / Medicine & Clinical Pharmacology
                                        104-4650David Kohler, Pharm.D.
                                        NCI / Medicine & Clinical Pharmacology
                                        104-2218-7Michelle Plante, Pharm.D.
                                        NHLBI / BMT / NCI Surgery
                                        104-4651Dale Grothe, Pharm.D.
                                        NIMH
                                        104-2242-7Stephen Piscitelli, Pharm.D.
                                        NIAID
                                        104-3044-7Gregory Susla, Pharm.D.
                                        MICU and NINDS
                                        104-2241-7Frank Pucino, Pharm.D.
                                        Ambulatory Care Services
                                        104-3043-7Alice Pau, Pharm.D.
                                        NIAID
                                        104-2240-7Karim Calis, Pharm.D., M.P.H.
                                        NICHD / Endocrinology & Genetics
                                                                                                                                                        NIDDK / Endocrinology & Gastroenterology
                                                                                                                                                        NIH Drug Information Service
                                        104-2619-7                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | Paul Jarosinski, P.D.          
|Paul Jarosinski, P.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      | NCI / Pediatric Oncology                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              | 104-2220-7                     
|Barry Goldspiel, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | NCI / Medicine & Clinical Pharmacology                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                | 104-4650                       
|David Kohler, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     | NCI / Medicine & Clinical Pharmacology                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                | 104-2218-7                     
|Michelle Plante, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | NHLBI / BMT / NCI Surgery                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             | 104-4651                       
|Dale Grothe, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      | NIMH                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | 104-2242-7                     
|Stephen Piscitelli, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               | NIAID                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | 104-3044-7                     
|Gregory Susla, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    | MICU and NINDS                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | 104-2241-7                     
|Frank Pucino, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     | Ambulatory Care Services                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              | 104-3043-7                     
|Alice Pau, Pharm.D.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | NIAID                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | 104-2240-7                     
|Karim Calis, Pharm.D., M.P.H.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              | NICHD / Endocrinology & Genetics
                                                                                                                                                        NIDDK / Endocrinology & Gastroenterology
                                                                                                                                                        NIH Drug Information Service                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                | 104-2619-7                     
|Up to Top                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | Pharmacy Residency Appointments 1997 - 1998

        Letitia Wright, Pharm.D.
                Howard University
                Specialized Resident in Primary Care Pharmacy PracticeFrank Pucino, Pharm.D.
                Program DirectorJudith Smith, Pharm.D.
                Albany College of Pharmacy
                Specialized Resident in Oncology 
                Pharmacy PracticeBarry R. Goldspiel, Pharm.D., FASHP
                Program DirectorRebecca E. Burton, Pharm.D.
                Virginia Commonwealth University
                Pharmacy Practice ResidentGregory M. Susla, Pharm.D.
                Program DirectorAmy M. Heck, Pharm.D.
                University of Cincinnati
                Specialized Resident in Drug Information Practice and PharmacotherapyKarim Anton Calis, Pharm.D., M.P.H.
                Program Director                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
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         The following is a list of non-antimicrobial drugs on which some form 
         of restriction has been placed by the Pharmacy and Therapeutics Committee:*
                Amiodarone (Cordarone®)Restricted to the Cardiology Service*
                Clozapine (Clozaril®)Restricted to use by physicians from NIMH and NINDS*
                Diltiazem (Cardizem CD®)Dilacor XR® can be automatically substituted for Cardizem CD®*
                Dornase Alfa (Pulmozyme®)Restricted for use in patients with cystic fibrosis (inpatient use only)*
                EMLA® Cream)This is a eutectic mixture of lidocaine and prilocaine which is 
                used in pediatric or adult patients to reduce the pain associated with 
                venipuncture, intravenous cannulation (especially in children in whom 
                intravenous access is difficult), lumbar puncture, and certain dermatologic 
                procedures. This drug should not be routinely used on mucous membranes 
                or prior to subcutaneous or intramuscular injections.*
                Enoxaparin (Lovenox®)Restricted to the Clinical Hematology Service*
                Epoetin Alfa (Epogen® or Procrit®)Drug use is evaluated through queries in MIS order screens*
                Filgrastim (Neupogen®)Drug use is evaluated through queries in MIS order screens*
                Granisetron (Kytril®)Usage guidelines were described in the May/June issue of Pharmacy Update*
                Ondansetron (Zofran®)Usage guidelines were described in the May/June issue of Pharmacy Update*
                Mexiletine (Mexitil®)Restricted to the Pain Management Service (for neuropathic pain)*
                Tizanidine (Zanaflex®)Use requires approval by the NINDS Neurology Consultation Service                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              



Drug Information Service

*
         Patient-specific medication information and pharmocotherapy consultations*
         Nutritional and metabolic support consultations*
         Comprehensive information about medications, biologics, nutrients, and drug therapy*
         Investigational drug information (pre-clinical and clinical)*
         Research support and assistance with study design, protocol development, and critical literature evaluation301-496-2407Pager 104-2619-7
         Building 10, Room 1N257
                                        
                Designed by Richard Barnes, NCRR, MAPB.Comments or questions concerning this
         site? ContactPharmacy Webmaster.National Institutes of Health (NIH) , Warren Grant Magnuson
         Clinical Center (CC)

         Pharmacy Department, Bethesda, Maryland 20892

         Last updated: July 18, 1997

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