Antiperspirants/Deodorants and Breast Cancer: Questions and Answers 

Key Points

• There is no conclusive research linking the use of underarm antiperspirants or 

deodorants and the subsequent development of breast cancer (see Question 1). 

• Research studies of underarm antiperspirants or deodorants and breast cancer have 

been completed and provide conflicting results (see Question 3). 

1. Can antiperspirants or deodorants cause breast cancer? 

Articles in the press and on the Internet have warned that underarm antiperspirants (a 

preparation that reduces underarm sweat) or deodorants (a preparation that destroys or 

masks unpleasant odors) cause breast cancer (1). The reports have suggested that these 

products contain harmful substances, which can be absorbed through the skin or enter the 

body through nicks caused by shaving. Some scientists have also proposed that certain 

ingredients in underarm antiperspirants or deodorants may be related to breast cancer 

because they are applied frequently to an area next to the breast (2, 3). 

However, researchers at the National Cancer Institute (NCI), a part of the National 

Institutes of Health, are not aware of any conclusive evidence linking the use of underarm

antiperspirants or deodorants and the subsequent development of breast cancer. The U.S. 

Food and Drug Administration (FDA), which regulates food, cosmetics, medicines, and 

medical devices, also does not have any evidence or research data that ingredients in 

underarm antiperspirants or deodorants cause cancer. 

2. What do scientists know about the ingredients in antiperspirants and deodorants? 

Aluminum-based compounds are used as the active ingredient in antiperspirants. These 

compounds form a temporary plug within the sweat duct that stops the flow of sweat to 

the skin's surface. Some research suggests that aluminum-based compounds, which are 

applied frequently and left on the skin near the breast, may be absorbed by the skin and 

cause estrogen-like (hormonal) effects (3). Because estrogen has the ability to promote 

3.66 

 1/4/08

 Page 1 
3.66 

1/4/08 

 Page 2 

the growth of breast cancer cells, some scientists have suggested that the aluminum-based 

compounds in antiperspirants may contribute to the development of breast cancer (3). 

Some research has focused on parabens, which are preservatives used in some deodorants 

and antiperspirants that have been shown to mimic the activity of estrogen in the body’s 

cells (4). Although parabens are used in many cosmetic, food, and pharmaceutical 

products, according to the FDA, most major brands of deodorants and antiperspirants in 

the United States do not currently contain parabens. Consumers can look at the 

ingredient label to determine if a deodorant or antiperspirant contains parabens. Parabens 

are usually easy to identify by name, such as methylparaben, propylparaben, 

butylparaben, or benzylparaben. The National Library of Medicine’s Household 

Products Database also has information about the ingredients used in most major brands 

of deodorants and antiperspirants. This database is available at 

http://householdproducts.nlm.nih.gov/index.htm on the Internet. 

The belief that parabens build up in breast tissue was supported by a 2004 study, which 

found parabens in 18 of 20 samples of tissue from human breast tumors (5). However, 

this study did not prove that parabens cause breast tumors (4). The authors of this study 

did not analyze healthy breast tissue or tissues from other areas of the body and did not 

demonstrate that parabens are found only in cancerous breast tissue (5). Furthermore, 

this research did not identify the source of the parabens and cannot establish that the 

buildup of parabens is due to the use of deodorants or antiperspirants. 

More research is needed to specifically examine whether the use of deodorants or 

antiperspirants can cause the buildup of parabens and aluminum-based compounds in 

breast tissue. Additional research is also necessary to determine whether these chemicals 

can either alter the DNA in some cells or cause other breast cell changes that may lead to 

the development of breast cancer. 

3. What have scientists learned about the relationship between antiperspirants or 

deodorants and breast cancer? 

In 2002, the results of a study looking for a relationship between breast cancer and 

underarm antiperspirants/deodorants were reported (6). This study did not show any 

increased risk for breast cancer in women who reported using an underarm antiperspirant 

or deodorant. The results also showed no increased breast cancer risk for women who 

reported using a blade (nonelectric) razor and an underarm antiperspirant or deodorant, or 

for women who reported using an underarm antiperspirant or deodorant within 1 hour of 

shaving with a blade razor. These conclusions were based on interviews with 

813 women with breast cancer and 793 women with no history of breast cancer. 

Findings from a different study examining the frequency of underarm shaving and 

antiperspirant/deodorant use among 437 breast cancer survivors were released in 2003 

(7). This study found that the age of breast cancer diagnosis was significantly earlier in 

women who used these products and shaved their underarms more frequently. 

Furthermore, women who began both of these underarm hygiene habits before 16 years 
3.66 

1/4/08 

 Page 3 

of age were diagnosed with breast cancer at an earlier age than those who began these 

habits later. While these results suggest that underarm shaving with the use of 

antiperspirants/deodorants may be related to breast cancer, it does not demonstrate a 

conclusive link between these underarm hygiene habits and breast cancer. 

In 2006, researchers examined antiperspirant use and other factors among 54 women with 

breast cancer and 50 women without breast cancer. The study found no association 

between antiperspirant use and the risk of breast cancer; however, family history and the 

use of oral contraceptives were associated with an increased risk of breast cancer (8). 

Because studies of antiperspirants and deodorants and breast cancer have provided 

conflicting results, additional research is needed to investigate this relationship and other 

factors that may be involved. 

4. Where can someone get more information on breast cancer risk? 

People who are concerned about their breast cancer risk are encouraged to talk with their 

doctor. More information about breast cancer risk can be found on the NCI’s Cancer 

Risk: Understanding the Puzzle Web site. This interactive Web site, which includes 

information about how to reduce breast cancer risk, can be accessed at 

http://understandingrisk.cancer.gov on the Internet. 

U.S. residents may wish to contact the NCI’s Cancer Information Service (CIS) (see 

below) with any remaining questions or concerns about breast cancer. Inquirers who live 

outside the United States may wish to contact the International Union Against Cancer 

(UICC) for information about a resource in their country. The UICC Web site is located 

at http://www.uicc.org on the Internet. Also, some countries have organizations that offer 

services similar to those of the U.S. CIS. A list of international cancer information 

services can be found at http://www.icisg.org/meet_memberslist.htm#full on the Internet. 

Selected References 

1. Jones J. Can rumors cause cancer? Journal of the National Cancer Institute 2000; 

92(18):1469–1471. 

2. Darbre PD. Underarm cosmetics and breast cancer. Journal of Applied Toxicology 2003; 

23(2):89–95. 

3. Darbre PD. Aluminium, antiperspirants and breast cancer. Journal of Inorganic 

Biochemistry 2005; 99(9):1912–1919. 

4. Harvey PW, Everett DJ. Significance of the detection of esters of p-hydroxybenzoic acid 

(parabens) in human breast tumours. Journal of Applied Toxicology 2004; 24(1):1–4. 

5. Darbre PD, Aljarrah A, Miller WR, et al. Concentrations of parabens in human breast 

tumours. Journal of Applied Toxicology 2004; 24(1):5–13. 
3.66 

1/4/08 

 Page 4 

6. Mirick DK, Davis S, Thomas DB. Antiperspirant use and the risk of breast cancer. 

Journal of the National Cancer Institute 2002; 94(20):1578–1580. 

7. McGrath KG. An earlier age of breast cancer diagnosis related to more frequent use of 

antiperspirants/deodorants and underarm shaving. European Journal of Cancer 2003; 

12(6):479–485. 

8. Fakri S, Al-Azzawi A, Al-Tawil N. Antiperspirant use as a risk factor for breast cancer 

in Iraq. Eastern Mediterranean Health Journal 2006; 12(3-4):478–482. 

# # # 

Related NCI materials and Web pages: 

• National Cancer Institute Fact Sheet 2.10, How To Evaluate Health Information on 

the Internet: Questions and Answers 

(http://www.cancer.gov/cancertopics/factsheet/Information/internet) 

• National Cancer Institute Fact Sheet, Estimating Breast Cancer Risk: Questions and 

Answers (http://www.cancer.gov/cancertopics/factsheet/estimating-breast-cancerrisk)

• PDQ® Prevention Summary for Patients on Breast Cancer 

(http://www.cancer.gov/cancertopics/pdq/prevention/breast/patient) 

• What You Need To Know AboutTM Breast Cancer 

(http://www.cancer.gov/cancertopics/wyntk/breast)

For more help, contact: 

NCI’s Cancer Information Service 

Telephone (toll-free): 1–800–4–CANCER (1–800–422–6237) 

TTY (toll-free): 1–800–332–8615

LiveHelp® online chat: https://cissecure.nci.nih.gov/livehelp/welcome.asp

This fact sheet was reviewed on 1/4/08