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Submission Information

Submission ID : 25349638 Submission Name : 2,5-Furandione, 3-hexadecenyldihydroAR Number : 

Chemical Information

CAS Number : 32072-96-1 Ninth Collective Index Name : 2,5-Furandione, 3-(hexadecenyl)dihydroSubmitter Information

Submitter's Name : EPA

Address : 

City : Washington

State : DC

ZIP/Postal Code: 

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Type of Submitter : Company

Technical Point of Contact Information

Technical Point of Contact : 

Title : 

Phone Number : 

Fax Number : 

E-Mail Address : 

Additional Technical Point of Contact Information

Technical Point of Contact : 

Title : 

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Fax Number : 

E-Mail Address : 

Sponsor Information

Sponsor's Name : EPA

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E-Mail Address : 

Type of Sponsor : Company

Technical Point of Contact Information

Technical Point of Contact : 

Title : 

Phone Number : 

Fax Number : 

E-Mail Address : 

 Acute Toxicity to Aquatic Vertebrates

CAS Number : 32072-96-1

Sponsored

Chemical Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Acute Toxicity To Aquatic Vertebrates

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test

Substance

Comments:

Sponsored

Chemical Result

Type:

Test Substance

Result Type:

Method - Acute Toxicity To Aquatic Vertebrates

Year Study

Performed:

Method/Guideline

Followed:

Other

Method/Guideline:

Deviations from

Method/Guideline:

Species:

GLP:

Analytical

Monitoring:

Test Type:

Test Vessel:

Water Media Type:

Test

Concentrations:

Nominal and

Measured

Concentrations:

Exposure Period:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Vehicle Used:

Vehicle Name:

Vehicle Amount

and Units:

Alkalinity:

Dissolved Oxygen:

pH Value:

Test Temperature

and Units:

Photo

(Light/Dark):

Salinity:

TOC:

Water Hardness:

Method/Guideline

Test Conditions

Remarks:

Limit Test:

Test Results - Acute Toxicity To Aquatic Vertebrates

NOEC Exposure

Duration:

NOEC:

LOEC Exposure

Duration:

LOEC:

NOELR Exposure

Duration:

NOELR:

LOELR Exposure

Duration:

LOELR:

LC/EC Mean Value : Exposure

Duration

Exposure

Units

LC/EC % Value

Description

Mean

Value

or

Lower

Mean

Value

Upper

Mean

Value

Units Effect

Observed

Basis for

Concentration
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Results Remarks:

Reliability/Data Quality - Acute Toxicity To Aquatic Vertebrates

Reliability:

Reliability

Remarks:

As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Acute Toxicity To Aquatic Vertebrates

Reference:

 Acute Toxicity to Aquatic Invertebrates

CAS Number : 32072-96-1

Sponsored

Chemical Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Acute Toxicity To Aquatic Invertebrates

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test

Substance

Comments:

Sponsored

Chemical Result

Type:

Test Substance

Result Type:

Method - Acute Toxicity To Aquatic Invertebrates

Year Study

Performed:

Method/Guideline

Followed:

Other

Method/Guideline:

Deviations from

Method/Guideline:

Species/In Vitro

System:

GLP:

Analytical

Monitoring:

Test Type:

Test Vessel:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Water Media Type:

Test

Concentrations:

Nominal and

Measured

Concentrations:

Exposure Period:

Vehicle Used:

Vehicle Name:

Vehicle Amount

and Units:

Alkalinity:

Dissolved Oxygen:

pH Value:

Test Temperature

and Units:

Photo

(Light/Dark):

Salinity:

TOC:

Water Hardness:

Method/Guideline

Test Conditions

Remarks:

Limit Test:

Test Results - Acute Toxicity To Aquatic Invertebrates

NOEC Exposure

Duration:

NOEC:

LOEC Exposure

Duration:

LOEC:

NOELR Exposure

Duration:

NOELR:

LOELR Exposure

Duration:

LOELR:

LC/EC Mean Value : Exposure

Duration

Exposure

Units

LC/EC % Value

Description

Mean

Value

or

Upper

Mean

Value

Units Effect

Observed

Basis for

Concentration
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Lower

Mean

Value

Results Remarks:

Reliability/Data Quality - Acute Toxicity To Aquatic Invertebrates

Reliability:

Reliability

Remarks:

As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Acute Toxicity To Aquatic Invertebrates

Reference:

 Acute Toxicity to Aquatic Plants

CAS Number : 32072-96-1

Sponsored

Chemical Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Acute Toxicity To Aquatic Plants

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test

Substance

Comments:

Sponsored

Chemical Result

Type:

Test Substance

Result Type:

Method - Acute Toxicity To Aquatic Plants

Year Study

Performed:

Method/Guideline

Followed:

Other

Method/Guideline:

Deviations from

Method/Guideline:

Species:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

GLP:

Analytical

Monitoring:

Test Type:

Test Vessel:

Water Media Type:

Test

Concentrations:

Nominal and

Measured

Concentrations:

Exposure Period:

Vehicle Used:

Vehicle Name:

Vehicle Amount

and Units:

Alkalinity:

Dissolved Oxygen:

pH Value:

Test Temperature

and Units:

Photo

(Light/Dark):

Salinity:

TOC:

Water Hardness:

Method/Guideline

Test Conditions

Remarks:

Limit Test:

Test Results - Acute Toxicity To Aquatic Plants

NOEC Exposure

Duration:

NOEC:

LOEC Exposure

Duration:

LOEC:

NOELR Exposure

Duration:

NOELR:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

LOELR Exposure

Duration:

LOELR:

Effect : Exposure

Duration

Exposure

Units

Type % Value

Description

Mean

Value

or

Lower

Mean

Value

Upper

Mean

Value

Units Basis

for

Effect

Basis for

Concentration

Results Remarks:

Reliability/Data Quality - Acute Toxicity To Aquatic Plants

Reliability:

Reliability

Remarks:

As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Acute Toxicity To Aquatic Plants

Reference:

 Acute Toxicity

CAS Number : 32072-96-1

Sponsored Chemical Name

:

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Acute Toxicity

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test Substance

Comments:

Sponsored Chemical Result

Type:

Method - Acute Toxicity

Route of Administration:

Type of Exposure:

Species:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Mammalian Strain:

Gender:

Number of Animals per

Dose:

Dose:

Year Study Performed:

Method/Guideline

Followed:

GLP:

Method/Guideline and

Test Condition Remarks:

Test Results - Acute Toxicity

Concentration (LC/LD) : LC/LD % Value

Description

Value/Lower

Concentration

Upper

Concentration

Units

Number of Deaths ( Male

):

Number of Deaths ( Female

):

Number of Deaths ( Total

):

Results Remarks:

Conclusion:

Reliability/Data Quality - Acute Toxicity

Reliability:

Reliability Remarks: As of February 2010, no data were available for this

endpoint.

Key Study Sponsor

Indicator:

Reference - Acute Toxicity

Reference:

 Repeated-Dose Toxicity

CAS Number : 32072-96-1
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Sponsored Chemical

Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Repeated-Dose Toxicity

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test

Substance Comments:

Sponsored Chemical

Result Type:

Method - Repeated-Dose Toxicity

Route of

Administration:

Type of Exposure:

Species:

Mammalian Strain:

Gender:

Number of Animals per

Dose:

Dose:

Year Study Performed:

Method/Guideline

Followed:

GLP:

Exposure Period:

Frequency of

Treatment:

Post-Exposure Period:

Method/Guideline and

Test Condition

Remarks:

Test Results - Repeated-Dose Toxicity

Concentration (LOAEL/

LOAEC/ NOAEL/

NOAEC) :

LOAEL/

LOAEC/

NOAEL/

NOAEC

Population Value

Description

Value/Lower

Concentration

Upper

Concentration

Units
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Results Remarks:

Conclusion:

Reliability/Data Quality - Repeated-Dose Toxicity

Reliability:

Reliability Remarks: As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Repeated-Dose Toxicity

Reference:

 Genetic Toxicity in vivo

CAS Number : 32072-96-1

Sponsored Chemical Name

:

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Genetic Toxicity in vivo

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test Substance

Comments:

Sponsored Chemical Result

Type:

Method - Genetic Toxicity in vivo

Type of Study:

Type of Test:

Route of Administration:

Type of Exposure:

Species:

Strain:

Gender:

Dose:

Year Study Performed:

Method/Guideline

Followed:

GLP:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Duration of Treatment/

Exposure Period and

Units:

Frequency of Treatment:

Positive, Negative, and

Solvent

Control Substance(s):

Number of Animals per Sex

and Dose Group:

Method/Guideline and

Test Condition Remarks:

Test Results - Genetic Toxicity in vivo

Systemic Toxicity:

Genotoxic Effect:

Results Remarks:

Conclusion:

Reliability/Data Quality - Genetic Toxicity in vivo

Reliability:

Reliability Remarks: As of February 2010, no data were available for this

endpoint.

Key Study Sponsor

Indicator:

Reference - Genetic Toxicity in vivo

Reference:

 Genetic Toxicity in vitro

CAS Number : 32072-96-1

Sponsored Chemical Name

:

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Genetic Toxicity in vitro

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test Substance

Comments:

Sponsored Chemical Result

Type:

Method - Genetic Toxicity in vitro

Type of Study:

Concentrations:

Year Study Performed:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Method/Guideline

Followed:

GLP:

Postive, Negative, and

Solvent

Control Substance(s):

Method/Guideline and

Test Condition Remarks:

Test Results - Genetic Toxicity in vitro

Details on Cytogenetic

Assay:

Statistics:

Effect : Species Other

Species

Strain Other

Strain

Metabolic

Activation

Genotoxic

Effect

Conclusion

Results Remarks:

Conclusion:

Reliability/Data Quality - Genetic Toxicity in vitro

Reliability:

Reliability Remarks: As of February 2010, no data were available for this

endpoint.

Key Study Sponsor

Indicator:

Reference - Genetic Toxicity in vitro

Reference:

 Reproductive Toxicity

CAS Number : 32072-96-1

Sponsored Chemical

Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Reproductive Toxicity

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

and Other Test

Substance Comments:

Sponsored Chemical

Result Type:

Method - Reproductive Toxicity

Route of

Administration:

Type of Exposure:

Species:

Mammalian Strain:

Gender:

Number of Animals per

Dose:

Dose:

Year Study Performed:

Method/Guideline

Followed:

GLP:

Exposure Period:

Frequency of

Treatment:

Post-Exposure Period:

Method/Guideline and

Test Condition

Remarks:

Pre-Mating Exposure /

Males:

Pre-Mating Exposure /

Females:

Test Results - Reproductive Toxicity

Concentration (LOAEL/

LOAEC/ NOAEL/

NOAEC) :

LOAEL/

LOAEC/

NOAEL/

NOAEC

Population Value

Description

Value/Lower

Concentration

Upper

Concentration

Units

Results:

Results Remarks:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

Conclusion:

Reliability/Data Quality - Reproductive Toxicity

Reliability:

Reliability Remarks: As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Reproductive Toxicity

Reference:

 Developmental Toxicity/Teratogenicity

CAS Number : 32072-96-1

Sponsored Chemical

Name :

2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance - Developmental Toxicity/Teratogenicity

Test Substance: (32072-96-1) 2,5-Furandione, 3-(hexadecenyl)dihydroTest Substance

Purity/Composition

and Other Test

Substance Comments:

Sponsored Chemical

Result Type:

Method - Developmental Toxicity/Teratogenicity

Route of

Administration:

Type of Exposure:

Species:

Mammalian Strain:

Gender:

Number of Animals per

Dose:

Dose:

Year Study Performed:

Method/Guideline

Followed:

GLP:

Exposure Period:

Frequency of

Treatment:
High Production Volume Information System (HPVIS) | High Production Volume (HPV) Challenge | OPPT | US EPA

http://iaspub.epa.gov/hpvis/ServSubmissionPrint[6/15/2011 10:33:17 AM]

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Post-Exposure Period:

Method/Guideline and

Test Condition

Remarks:

Test Results - Developmental Toxicity/Teratogenicity

Concentration (LOAEL/

LOAEC/ NOAEL/

NOAEC) :

LOAEL/

LOAEC/

NOAEL/

NOAEC

Population Value

Description

Value/Lower

Concentration

Upper

Concentration

Units

Results Remarks:

Conclusion:

Reliability/Data Quality - Developmental Toxicity/Teratogenicity

Reliability:

Reliability Remarks: As of February 2010, no data were available for this endpoint.

Key Study Sponsor

Indicator:

Reference - Developmental Toxicity/Teratogenicity

Reference: