Federal Register / Vol. 69, No. 201 / Tuesday, October 19, 2004 / Notices 61485

to the matters under review, and lack of 

bias. Though financial conflicts of 

interest, the appearance of lack of 

impartiality, lack of independence, and 

bias may result in disqualification, the 

absence of such concerns does not 

assure that a candidate will be selected 

to serve on the FIFRA SAP. Numerous 

qualified candidates are identified for 

each panel. Therefore, selection 

decisions involve carefully weighing a 

number of factors including, the 

candidates’ areas of expertise and 

professional qualifications, and 

achieving an overall balance of different 

scientific perspectives on the panel. In 

order to have the collective breadth of 

experience needed to address the 

Agency’s charge for this meeting, the 

Agency anticipates selecting 

approximately 12 ad hoc scientists. 

If a prospective candidate for service 

on the FIFRA SAP is considered for 

participation in a particular session, the 

candidate is subject to the provisions of 

5 CFR part 2634, Executive Branch 

Financial Disclosure, as supplemented 

by the EPA in 5 CFR part 6401. As such, 

the FIFRA SAP candidate is required to 

submit a Confidential Financial 

Disclosure Form for Special 

Government Employees Serving on 

Federal Advisory Committees at EPA 

(EPA Form 3110–48 5–02) which shall 

fully disclose, among other financial 

interests, the candidate’s employment, 

stocks, and bonds, and where 

applicable, sources of research support. 

EPA will evaluate the candidate’s 

financial disclosure form to assess that 

there are no financial conflicts of 

interest, no appearance of lack of 

impartiality, and no prior involvement 

with the development of the primary 

documents under consideration before 

the candidate is considered further for 

service on the FIFRA SAP.

Those who are selected from the pool 

of prospective candidates will be asked 

to attend the public meetings and to 

participate in the discussion of key 

issues and assumptions at these 

meetings. In addition, they will be asked 

to review and to help finalize the 

meeting minutes. The list of FIFRA SAP 

members participating at this meeting 

will be posted on the FIFRA SAP web 

site or may be obtained by contacting 

the PIRIB at the address or telephone 

number listed in Unit I.

II. Background

A. Purpose of the FIFRA SAP

Amendments to FIFRA enacted 

November 28, 1975 (7 U.S.C. 136w(d)), 

include a requirement under section 

25(d) of FIFRA that notices of intent to 

cancel or reclassify pesticide 

registrations pursuant to section 6(b)(2) 

of FIFRA, as well as proposed and final 

forms of regulations pursuant to section 

25(a) of FIFRA, be submitted to a SAP 

prior to being made public or issued to 

a registrant. In accordance with section 

25(d) of FIFRA, the FIFRA SAP is to 

have an opportunity to comment on the 

health and environmental impact of 

such actions. The FIFRA SAP also shall 

make comments, evaluations, and 

recommendations for operating 

guidelines to improve the effectiveness 

and quality of analyses made by Agency 

scientists. Members are scientists who 

have sufficient professional 

qualifications, including training and 

experience, to be capable of providing 

expert comments as to the impact on 

health and the environment of 

regulatory actions under sections 6(b) 

and 25(a) of FIFRA. The Deputy 

Administrator appoints seven 

individuals to serve on the FIFRA SAP 

for staggered terms of 4 years, based on 

recommendations from the National 

Institutes of Health and the National 

Science Foundation.

Section 104 of FQPA (Public Law 

104–170) established the FQPA Science 

Review Board (SRB). These scientists 

shall be available to the FIFRA SAP on 

an ad hoc basis to assist in reviews 

conducted by the FIFRA SAP.

B. Public Meeting

The FIFRA SAP will meet to consider 

and review the N-methyl carbamate 

cumulative risk assessment (CRA) 

strategies, and methodologies for 

exposure assessment. The FQPA of 1996 

amended the laws under which EPA 

evaluates the safety of pesticide residues 

in food. Section 408(b)(2)(D)(v) and (vi) 

of the Federal Food, Drug, and Cosmetic 

Act, as amended by FQPA, specifies that 

when determining the safety of a 

pesticide chemical, EPA shall base its 

risk assessment on aggregate exposure 

(i.e., total dietary including drinking 

water, residential, and other nonoccupational exposure) and available 

information concerning the cumulative 

effects to human health that may result 

from exposure to pesticides and other 

substances that have a common 

mechanism of toxicity. 

EPA is currently preparing a CRA for 

the N-methyl carbamate class of 

pesticides. The specific N-methyl 

carbamate pesticides which will be 

included in this assessment are the 

following: Aldicarb; carbaryl; 

carbofuran; formetanate hydrochloride; 

methiocarb; methomyl; oxamyl; 

pirimicarb; propoxur; and thiodicarb 

(see Federal Register notice dated 

February 4, 2004 (69 FR 5340) (FRL–

7334–4)). As was previously done for 

the CRA for the organophosphorus 

pesticides, EPA will convene several 

meetings of the FIFRA SAP to review a 

number of science issues which are 

crucial to the development and 

completion of the N-methyl carbamate 

CRA.

The first meeting that is being 

announced in the Federal Register

notice will be held on December 3, 

2004, and will deal with general 

strategies, and methodologies being 

considered for use in this CRA and 

discuss some of the overall issues to be 

covered at a subsequent meeting of the 

SAP scheduled for February 2005.

A separate Federal Register notice 

will be issued later announcing the 

February meeting. In addition to general 

proposed strategies and methodologies 

for the N-methyl carbamate CRA, 

specific topics to be discussed at the 

December 3, 2004, SAP meeting 

include, sophisticated PBPK modeling, 

as well as more conventional relativepotency based approaches, the interface 

between the exposure models and the 

PBPK models, and proposals to revise 

current exposure models to evaluate 

exposure periods of less than 24 hours.

C. FIFRA SAP Meeting Minutes

The FIFRA SAP will prepare meeting 

minutes summarizing its 

recommendations to the Agency in 

approximately 60 days after the 

meeting. The meeting minutes will be 

posted on the FIFRA SAP web site or 

may be obtained by contacting the PIRIB 

at the address or telephone number 

listed in Unit I.

List of Subjects

Environmental protection, Pesticides 

and pests.

Dated: October 12, 2004.

Joseph J. Merenda, Jr.,

Director, Office of Science Coordination and 

Policy.

[FR Doc. 04–23396 Filed 10–18–04; 8:45 am]

BILLING CODE 6560–50–S

ENVIRONMENTAL PROTECTION 

AGENCY

[OPP–2004–0343; FRL–7684–6]

FIFRA Scientific Advisory Panel; 

Notice of Public Meeting

AGENCY: Environmental Protection 

Agency (EPA).

ACTION: Notice.

SUMMARY: There will be a 1–day meeting 

of the Federal Insecticide, Fungicide, 

and Rodenticide Act Scientific Advisory 

61486 Federal Register / Vol. 69, No. 201 / Tuesday, October 19, 2004 / Notices 

Panel (FIFRA SAP) to consider and 

review the use of pharmacokinetic data 

to refine carbaryl risk estimates from 

oral and dermal exposure.

DATES: The meeting will be held on 

December 2, 2004, from 8:30 a.m. to 

approximately 5 p.m., eastern time.

Comments: The deadlines for the 

submission of requests to present oral 

comments and the submission of 

written comments, see Unit I.E. of the 

SUPPLEMENTARY INFORMATION. 

Nominations: Nominations of 

scientific experts to serve as ad hoc 

members of the FIFRA SAP for this 

meeting should be provided on or before 

October 29, 2004. 

Special seating: Requests for special 

seating arrangements should be made at 

least 5 business days prior to the 

meeting.

ADDRESSES: The meeting will be held at 

the Holiday Inn Rosslyn at Key Bridge, 

1900 North Fort Myer Drive, Arlington, 

VA 22209. The telephone number for 

the Holiday Inn Rosslyn at Key Bridge 

is (703) 807–2000.

Comments: Written comments may 

be submitted electronically (preferred), 

through hand delivery/courier, or by 

mail. Follow the detailed instructions as 

provided in Unit I. of the 

SUPPLEMENTARY INFORMATION.

Nominations, requests to present oral 

comments, and special seating: To 

submit nominations for ad hoc members 

of the FIFRA SAP for this meeting, 

requests for special seating 

arrangements, or requests to present oral 

comments, notify the Designated 

Federal Official (DFO) listed under FOR

FURTHER INFORMATION CONTACT. To 

ensure proper receipt by EPA, your 

request must identify docket ID number 

OPP–2004–0343 in the subject line on 

the first page of your response.

FOR FURTHER INFORMATION CONTACT:

Joseph E. Bailey, DFO, Office of Science 

Coordination and Policy (7201M), 

Environmental Protection Agency, 1200 

Pennsylvania Ave., NW., Washington, 

DC 20460; telephone number: (202) 

564–2045; fax number: (202) 564–8382; 

e-mail addresses: 

bailey.joseph@epa.gov.

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this Action Apply to Me?

This action is directed to the public 

in general. This action may, however, be 

of interest to persons who are or may be 

required to conduct testing of chemical 

substances under the Federal Food, 

Drug, and Cosmetic Act (FFDCA), 

FIFRA, and the Food Quality Protection 

Act of 1996 (FQPA). Since other entities 

may also be interested, the Agency has 

not attempted to describe all the specific 

entities that may be affected by this 

action. If you have any questions 

regarding the applicability of this action 

to a particular entity, consult the DFO 

listed under FOR FURTHER INFORMATION

CONTACT.

B. How Can I Get Copies of this 

Document and Other Related 

Information?

1. Docket. EPA has established an 

official public docket for this action 

under docket ID number OPP–2004–

0343. The official public docket consists 

of the documents specifically referenced 

in this action, any public comments 

received, and other information related 

to this action. Although, a part of the 

official docket, the public docket does 

not include Confidential Business 

Information (CBI) or other information 

whose disclosure is restricted by statute. 

The official public docket is the 

collection of materials that is available 

for public viewing at the Public 

Information and Records Integrity 

Branch (PIRIB), Rm. 119, Crystal Mall 

#2, 1801 S. Bell St., Arlington, VA. This 

docket facility is open from 8:30 a.m. to 

4 p.m., Monday through Friday, 

excluding legal holidays. The docket 

telephone number is (703) 305–5805.

2. Electronic access. You may access 

this Federal Register document 

electronically through the EPA Internet 

under the ‘‘Federal Register’’ listings at 

http://www.epa.gov/fedrgstr/.

EPA’s position paper, charge/

questions to FIFRA SAP, FIFRA SAP 

composition (i.e., members and 

consultants for this meeting), and the 

meeting agenda will be available as soon 

as possible, but no later than midNovember 2004. In addition, the Agency 

may provide additional background 

documents as the materials become 

available. You may obtain electronic 

copies of these documents, and certain 

other related documents that might be 

available electronically, from the FIFRA 

SAP Internet Home Page at http://

www.epa.gov/scipoly/sap.

An electronic version of the public 

docket is available through EPA’s 

electronic public docket and comment 

system, EPA Dockets. You may use EPA 

Dockets at http://www.epa.gov/edocket/

to submit or view public comments, 

access the index listing of the contents 

of the official public docket, and to 

access those documents in the public 

docket that are available electronically. 

Once in the system, select ‘‘search,’’

then key in the appropriate docket ID 

number.

Certain types of information will not 

be placed in EPA Dockets. Information 

claimed as CBI and other information 

whose disclosure is restricted by statute, 

which is not included in the official 

public docket, will not be available for 

public viewing in EPA’s electronic 

public docket. EPA’s policy is that 

copyrighted material will not be placed 

in EPA’s electronic public docket but 

will be available only in printed, paper 

form in the official public docket. To the 

extent feasible, publicly available 

docket materials will be made available 

in EPA’s electronic public docket. When 

a document is selected from the index 

list in EPA Dockets, the system will 

identify whether the document is 

available for viewing in EPA’s electronic 

public docket. Although not all docket 

materials may be available 

electronically, you may still access any 

of the publicly available docket 

materials through the docket facility 

identified in Unit I.B.1. EPA intends to 

work towards providing electronic 

access to all of the publicly available 

docket materials through EPA’s 

electronic public docket.

For public commenters, it is 

important to note that EPA’s policy is 

that public comments, whether 

submitted electronically or in paper, 

will be made available for public 

viewing in EPA’s electronic public 

docket as EPA receives them and 

without change, unless the comment 

contains copyrighted material, CBI, or 

other information whose disclosure is 

restricted by statute. When EPA 

identifies a comment containing 

copyrighted material, EPA will provide 

a reference to that material in the 

version of the comment that is placed in 

EPA’s electronic public docket. The 

entire printed comment, including the 

copyrighted material, will be available 

in the public docket.

Public comments submitted on 

computer disks that are mailed or 

delivered to the docket will be 

transferred to EPA’s electronic public 

docket. Public comments in hard copy 

that are mailed or delivered to the 

docket will be scanned and placed in 

EPA’s electronic public docket. Where 

practical, physical objects will be 

photographed, and the photograph will 

be placed in EPA’s electronic public 

docket along with a brief description 

written by the docket staff.

C. How and to Whom Do I Submit 

Comments?

You may submit comments 

electronically (preferred), through hand 

delivery/courier, or by mail. To ensure 

proper receipt by EPA, identify the 

appropriate docket ID number in the 

subject line on the first page of your 

comment. Please ensure that your 

Federal Register / Vol. 69, No. 201 / Tuesday, October 19, 2004 / Notices 61487

comments are submitted within the 

specified comment period. Comments 

received after the close of the comment 

period will be marked ‘‘late.’’ EPA is not 

required to consider these late 

comments. Do not use EPA Dockets or 

e-mail to submit CBI or information 

protected by statute.

1. Electronically. If you submit an 

electronic comment as prescribed in this 

unit, EPA recommends that you include 

your name, mailing address, and an email address or other contact 

information in the body of your 

comment. Also include this contact 

information on the outside of any disk 

or CD ROM you submit, and in any 

cover letter accompanying the disk or 

CD ROM. This ensures that you can be 

identified as the submitter of the 

comment and allows EPA to contact you 

in case EPA cannot read your comment 

due to technical difficulties or needs 

further information on the substance of 

your comment. EPA’s policy is that EPA 

will not edit your comment, and any 

identifying or contact information 

provided in the body of a comment will 

be included as part of the comment that 

is placed in the official public docket, 

and made available in EPA’s electronic 

public docket. If EPA cannot read your 

comment due to technical difficulties 

and cannot contact you for clarification, 

EPA may not be able to consider your 

comment. 

i. EPA Dockets. Your use of EPA’s 

electronic public docket to submit 

comments to EPA electronically is 

EPA’s preferred method for receiving 

comments. Go directly to EPA Dockets 

at http://www.epa.gov/edocket/, and 

follow the online instructions for 

submitting comments. Once in the 

system, select ‘‘search,’’ and then key in 

docket ID number OPP–2004–0343. The 

system is an ‘‘anonymous access’’

system, which means EPA will not 

know your identity, e-mail address, or 

other contact information unless you 

provide it in the body of your comment.

ii. E-mail. Comments may be sent by 

e-mail to opp-docket@epa.gov, 

Attention: Docket ID Number OPP–

2004–0343. In contrast to EPA’s 

electronic public docket, EPA’s e-mail 

system is not an ‘‘anonymous access’’

system. If you send an e-mail comment 

directly to the docket without going 

through EPA’s electronic public docket, 

EPA’s e-mail system automatically 

captures your e-mail address. E-mail 

addresses that are automatically 

captured by EPA’s e-mail system are 

included as part of the comment that is 

placed in the official public docket, and 

made available in EPA’s electronic 

public docket.

iii. Disk or CD ROM. You may submit 

comments on a disk or CD ROM that 

you deliver as described in Unit I.C.2 or 

mail to the address provided in Unit 

I.C.3. These electronic submissions will 

be accepted in WordPerfect or ASCII file 

format. Avoid the use of special 

characters and any form of encryption.

2. By hand delivery or courier. Deliver 

your comments to: Public Information 

and Records Integrity Branch (PIRIB), 

Office of Pesticide Programs (OPP), 

Environmental Protection Agency, Rm. 

119, Crystal Mall #2, 1801 S. Bell St., 

Arlington, VA, Attention: Docket ID 

Number OPP–2004–0343. Such 

deliveries are only accepted during the 

docket’s normal hours of operation as 

identified in Unit I.B.1.

3. By mail. Due to potential delays in 

EPA’s receipt and processing of mail, 

respondents are strongly encouraged to 

submit comments either electronically 

or by hand delivery or courier. We 

cannot guarantee that comments sent 

via mail will be received prior to the 

close of the comment period. If mailed, 

please send your comments to: Public 

Information and Records Integrity 

Branch (PIRIB) (7502C), Office of 

Pesticide Programs (OPP), 

Environmental Protection Agency, 1200 

Pennsylvania Ave., NW., Washington, 

DC 20460–0001, Attention: Docket ID 

Number OPP–2004–0343.

D. What Should I Consider as I Prepare 

My Comments for EPA?

You may find the following 

suggestions helpful for preparing your 

comments:

1. Explain your views as clearly as 

possible. 

2. Describe any assumptions that you 

used. 

3. Provide copies of any technical 

information and/or data you used that 

support your views. 

4. Provide specific examples to 

illustrate your concerns. 

5. Make sure to submit your 

comments by the deadline in this 

document. 

6. To ensure proper receipt by EPA, 

be sure to identify the docket ID number 

assigned to this action in the subject 

line on the first page of your response. 

You may also provide the name, date, 

and Federal Register citation. 

E. How May I Participate in this 

Meeting?

You may participate in this meeting 

by following the instructions in this 

unit. To ensure proper receipt by EPA, 

it is imperative that you identify docket 

ID number OPP–2004–0343 in the 

subject line on the first page of your 

request.

1. Oral comments. Oral comments 

presented at the meetings should not be 

repetitive of previously submitted oral 

or written comments. Although requests 

to present oral comments are accepted 

until the date of the meeting (unless 

otherwise stated), to the extent that time 

permits, interested persons may be 

permitted by the Chair of FIFRA SAP to 

present oral comments at the meeting. 

Each individual or group wishing to 

make brief oral comments to FIFRA SAP 

is strongly advised to submit their 

request to the DFO listed under FOR

FURTHER INFORMATION CONTACT no later 

than noon, eastern time, November 24, 

2004, in order to be included on the 

meeting agenda. The request should 

identify the name of the individual 

making the presentation, the 

organization (if any) the individual will 

represent, and any requirements for 

audiovisual equipment (e.g., overhead 

projector, 35mm projector, chalkboard). 

Oral comments before FIFRA SAP are 

limited to approximately 5 minutes 

unless prior arrangements have been 

made. In addition, each speaker should 

bring 30 copies of his or her comments 

and presentation slides for distribution 

to FIFRA SAP at the meeting.

2. Written comments. Although 

submission of written comments are 

accepted until the date of the meeting 

(unless otherwise stated), the Agency 

encourages that written comments be 

submitted, using the instructions in 

Unit I., no later than noon, eastern time, 

November 18, 2004, to provide FIFRA 

SAP the time necessary to consider and 

review the written comments. There is 

no limit on the extent of written 

comments for consideration by FIFRA 

SAP. Persons wishing to submit written 

comments at the meeting should contact 

the DFO listed under FOR FURTHER

INFORMATION CONTACT and submit 30 

copies.

3. Seating at the meeting. Seating at 

the meeting will be on a first-come 

basis. Individuals requiring special 

accommodations at this meeting, 

including wheelchair access and 

assistance for the hearing impaired, 

should contact the DFO at least 5 

business days prior to the meeting using 

the information under FOR FURTHER

INFORMATION CONTACT so that 

appropriate arrangements can be made.

4. Request for nominations of 

prospective candidates for service as ad 

hoc members of the FIFRA SAP for this 

meeting. As part of a broader process for 

developing a pool of candidates for each 

meeting, the FIFRA SAP staff routinely 

solicit the stakeholder community for 

nominations of prospective candidates 

for service as ad hoc members of the 

FIFRA SAP. Any interested person or 

61488 Federal Register / Vol. 69, No. 201 / Tuesday, October 19, 2004 / Notices 

organization may nominate qualified 

individuals to be considered as 

prospective candidates for a specific 

meeting. Individuals nominated for this 

meeting should have expertise in one or 

more of the following areas: 

Pharmacokinetics/pharmacodynamics, 

toxicology, and exposure. Nominees 

should be scientists who have sufficient 

professional qualifications, including 

training and experience, to be capable of 

providing expert comments on the 

scientific issues for this meeting. 

Nominees should be identified by name, 

occupation, position, address, and 

telephone number. Nominations should 

be provided to the DFO listed under FOR

FURTHER INFORMATION CONTACT on or 

before October 29, 2004. The Agency 

will consider all nominations of 

prospective candidates for this meeting 

that are received on or before this date. 

However, final selection of ad hoc 

members for this meeting is a 

discretionary function of the Agency.

The selection of scientists to serve on 

the FIFRA SAP is based on the function 

of the panel and the expertise needed to 

address the Agency’s charge to the 

panel. No interested scientists shall be 

ineligible to serve by reason of their 

membership on any other advisory 

committee to a Federal department or 

agency or their employment by a 

Federal department or agency (except 

the EPA). Other factors considered 

during the selection process include 

availability of the potential panel 

member to fully participate in the 

panel’s reviews, absence of any conflicts 

of interest or appearance of lack of 

impartiality, independence with respect 

to the matters under review, and lack of 

bias. Though financial conflicts of 

interest, the appearance of lack of 

impartiality, lack of independence, and 

bias may result in disqualification, the 

absence of such concerns does not 

assure that a candidate will be selected 

to serve on the FIFRA SAP. Numerous 

qualified candidates are identified for 

each panel. Therefore, selection 

decisions involve carefully weighing a 

number of factors including, the 

candidates’ areas of expertise and 

professional qualifications, and 

achieving an overall balance of different 

scientific perspectives on the panel. In 

order to have the collective breadth of 

experience needed to address the 

Agency’s charge for this meeting, the 

Agency anticipates selecting 

approximately 12 ad hoc scientists.

If a prospective candidate for service 

on the FIFRA SAP is considered for 

participation in a particular session, the 

candidate is subject to the provisions of 

5 CFR part 2634, Executive Branch 

Financial Disclosure, as supplemented 

by the EPA in 5 CFR part 6401. As such, 

the FIFRA SAP candidate is required to 

submit a Confidential Financial 

Disclosure Form for Special 

Government Employees Serving on 

Federal Advisory Committees at EPA 

(EPA Form 3110–48 5–02) which shall 

fully disclose, among other financial 

interests, the candidate’s employment, 

stocks, and bonds, and where 

applicable, sources of research support. 

EPA will evaluate the candidate’s 

financial disclosure form to assess that 

there are no financial conflicts of 

interest, no appearance of lack of 

impartiality, and no prior involvement 

with the development of the primary 

documents under consideration before 

the candidate is considered further for 

service on the FIFRA SAP.

Those who are selected from the pool 

of prospective candidates will be asked 

to attend the public meetings and to 

participate in the discussion of key 

issues and assumptions at these 

meetings. In addition, they will be asked 

to review and to help finalize the 

meeting minutes. The list of FIFRA SAP 

members participating at this meeting 

will be posted on the FIFRA SAP 

website or may be obtained by 

contacting the PIRIB at the address or 

telephone number listed in Unit I.

II. Background

A. Purpose of the FIFRA SAP

Amendments to FIFRA enacted 

November 28, 1975 (7 U.S.C. 136w(d)), 

include a requirement under section 

25(d) of FIFRA that notices of intent to 

cancel or reclassify pesticide 

registrations pursuant to section 6(b)(2) 

of FIFRA, as well as proposed and final 

forms of regulations pursuant to section 

25(a) of FIFRA, be submitted to a SAP 

prior to being made public or issued to 

a registrant. In accordance with section 

25(d) of FIFRA, the FIFRA SAP is to 

have an opportunity to comment on the 

health and environmental impact of 

such actions. The FIFRA SAP also shall 

make comments, evaluations, and 

recommendations for operating 

guidelines to improve the effectiveness 

and quality of analyses made by Agency 

scientists. Members are scientists who 

have sufficient professional 

qualifications, including training and 

experience, to be capable of providing 

expert comments as to the impact on 

health and the environment of 

regulatory actions under sections 6(b) 

and 25(a) of FIFRA. The Deputy 

Administrator appoints seven 

individuals to serve on the FIFRA SAP 

for staggered terms of 4 years, based on 

recommendations from the National 

Institutes of Health and the National 

Science Foundation.

Section 104 of FQPA (Public Law 

104–170) established the FQPA Science 

Review Board (SRB). These scientists 

shall be available to the FIFRA SAP on 

an ad hoc basis to assist in reviews 

conducted by the FIFRA SAP.

B. Public Meeting

The FIFRA SAP will meet to consider 

and review the use of pharmacokinetic 

data to refine carbaryl risk estimates 

from oral and dermal exposure. The 

Agency recently completed a human 

health risk assessment for carbaryl and 

has since, received a proposal to use 

pharmacokinetic data to refine risk 

estimates from oral and dermal 

exposure from carbaryl use on 

residential turf. These exposures 

include, post-application dermal 

exposure on turf, and hand-to-mouth, 

object-to-mouth, and soil ingestion 

exposures in children. The proposal 

offers a refined approach to calculating 

a margin of exposure based on target 

tissue concentrations. This approach 

compares internal doses in the target 

tissue, brain, rather than comparing 

administered doses. The proposal to use 

this approach was based upon the 

pharmacokinetic and pharmacodynamic 

characteristics of carbaryl. Carbaryl has 

a short half-life in the body and the 

duration of binding to cholinesterase 

enzymes is brief. Because of these 

characteristics, peak brain levels rather 

than total exposure were proposed for 

exposure assessment. The purpose of 

this SAP meeting is to evaluate whether 

comparison of internal doses in target 

tissue is a useful way to refine carbaryl 

risk estimates, and to evaluate the 

approach used to estimate brain 

concentrations from intermittent 

exposure using pharmacokinetic data.

C. FIFRA SAP Meeting Minutes

The FIFRA SAP will prepare meeting 

minutes summarizing its 

recommendations to the Agency in 

approximately 60 days after the 

meeting. The meeting minutes will be 

posted on the FIFRA SAP web site or 

may be obtained by contacting the PIRIB 

at the address or telephone number 

listed in Unit I.

List of Subjects

Environmental protection, Pesticides 

and pests.

Federal Register / Vol. 69, No. 201 / Tuesday, October 19, 2004 / Notices 61489

Dated: October 12, 2004.

Joseph J. Merenda, Jr.,

Director, Office of Science Coordination and 

Policy.

[FR Doc. 04–23397 Filed 10–18–04; 8:45 am]

BILLING CODE 6560–50–S

ENVIRONMENTAL PROTECTION 

AGENCY

[OPPT–2004–0120; FRL–7685–2]

Certain New Chemicals; Receipt and 

Status Information

AGENCY: Environmental Protection 

Agency (EPA).

ACTION: Notice.

SUMMARY: Section 5 of the Toxic 

Substances Control Act (TSCA) requires 

any person who intends to manufacture 

(defined by statute to include import) a 

new chemical (i.e., a chemical not on 

the TSCA Inventory) to notify EPA and 

comply with the statutory provisions 

pertaining to the manufacture of new 

chemicals. Under sections 5(d)(2) and 

5(d)(3) of TSCA, EPA is required to 

publish a notice of receipt of a 

premanufacture notice (PMN) or an 

application for a test marketing 

exemption (TME), and to publish 

periodic status reports on the chemicals 

under review and the receipt of notices 

of commencement to manufacture those 

chemicals. This status report, which 

covers the period from September 13, 

2004 to October 1, 2004, consists of the 

PMNs, pending or expired, and the 

notices of commencement to 

manufacture a new chemical that the 

Agency has received under TSCA 

section 5 during this time period.

DATES: Comments identified by the 

docket identification (ID) number 

OPPT–2004–0120 and the specific PMN 

number or TME number, must be 

received on or before November 18, 

2004.

ADDRESSES: Comments may be 

submitted electronically, by mail, or 

through hand delivery/courier. Follow 

the detailed instructions as provided in 

Unit I. of the SUPPLEMENTARY

INFORMATION.

FOR FURTHER INFORMATION CONTACT:

Colby Lintner, Regulatory Coordinator, 

Environmental Assistance Division, 

Office of Pollution Prevention and 

Toxics (7408M), Environmental 

Protection Agency, 1200 Pennsylvania 

Ave., NW., Washington, DC 20460–

0001; telephone number: (202) 554–

1404; e-mail address: TSCAHotline@epa.gov.

SUPPLEMENTARY INFORMATION:

I. General Information

A. Does this Action Apply to Me?

This action is directed to the public 

in general. As such, the Agency has not 

attempted to describe the specific 

entities that this action may apply to. 

Although others may be affected, this 

action applies directly to the submitter 

of the premanufacture notices addressed 

in the action. If you have any questions 

regarding the applicability of this action 

to a particular entity, consult the person 

listed under FOR FURTHER INFORMATION

CONTACT.

B. How Can I Get Copies of this 

Document and Other Related 

Information?

1. Docket. EPA has established an 

official public docket for this action 

under docket ID number OPPT–2004–

0120. The official public docket consists 

of the documents specifically referenced 

in this action, any public comments 

received, and other information related 

to this action. Although a part of the 

official docket, the public docket does 

not include Confidential Business 

Information (CBI) or other information 

whose disclosure is restricted by statute. 

The official public docket is the 

collection of materials that is available 

for public viewing at the EPA Docket 

Center, Rm. B102-Reading Room, EPA 

West, 1301 Constitution Ave., NW., 

Washington, DC. The EPA Docket 

Center is open from 8:30 a.m. to 4:30 

p.m., Monday through Friday, excluding 

legal holidays. The EPA Docket Center 

Reading Room telephone number is 

(202) 566–1744 and the telephone 

number for the OPPT Docket, which is 

located in EPA Docket Center, is (202) 

566–0280.

2. Electronic access. You may access 

this Federal Register document 

electronically through the EPA Internet 

underthe ‘‘Federal Register’’ listings 

athttp://www.epa.gov/fedrgstr/.

An electronic version of the public 

docket is available through EPA’s 

electronic public docket and comment 

system, EPA Dockets. You may use EPA 

Dockets at http://www.epa.gov/edocket/

to submit or view public comments, 

access the index listing of the contents 

of the official public docket, and to 

access those documents in the public 

docket that are available electronically. 

Although not all docket materials may 

be available electronically, you may still 

access any of the publicly available 

docket materials through the docket 

facility identified in Unit I.B.1. Once in 

the system, select ‘‘search,’’ then key in 

the appropriate docket ID number.

Certain types of information will not 

be placed in the EPA Dockets. 

Information claimed as CBI and other 

information whose disclosure is 

restricted by statute, which is not 

included in the official public docket, 

will not be available for public viewing 

in EPA’s electronic public docket. EPA’s 

policy is that copyrighted material will 

not be placed in EPA’s electronic public 

docket but will be available only in 

printed, paper form in the official public 

docket. To the extent feasible, publicly 

available docket materials will be made 

available in EPA’s electronic public 

docket. When a document is selected 

from the index list in EPA Dockets, the 

system will identify whether the 

document is available for viewing in 

EPA’s electronic public docket. 

Although not all docket materials may 

be available electronically, you may still 

access any of the publicly available 

docket materials through the docket 

facility identified in Unit I.B.1. EPA 

intends to work towards providing 

electronic access to all of the publicly 

available docket materials through 

EPA’s electronic public docket.

For public commenters, it is 

important to note that EPA’s policy is 

that public comments, whether 

submitted electronically or in paper, 

will be made available for public 

viewing in EPA’s electronic public 

docket as EPA receives them and 

without change, unless the comment 

contains copyrighted material, CBI, or 

other information whose disclosure is 

restricted by statute. When EPA 

identifies a comment containing 

copyrighted material, EPA will provide 

a reference to that material in the 

version of the comment that is placed in 

EPA’s electronic public docket. The 

entire printed comment, including the 

copyrighted material, will be available 

in the public docket.

Public comments submitted on 

computer disks that are mailed or 

delivered to the docket will be 

transferred to EPA’s electronic public 

docket. Public comments that are 

mailed or delivered to the docket will be 

scanned and placed in EPA’s electronic 

public docket. Where practical, physical 

objects will be photographed, and the 

photograph will be placed in EPA’s 

electronic public docket along with a 

brief description written by the docket 

staff.

C. How and To Whom Do I Submit 

Comments?

You may submit comments 

electronically, by mail, or through hand 

delivery/courier. To ensure proper 

receipt by EPA, identify the appropriate 

docket ID number and specific PMN 

number or TME number in the subject 

line on the first page of your comment.