62050 Federal Register / Vol. 69, No. 204 / Friday, October 22, 2004 / Notices 

(CERCLA or Superfund) (42 U.S.C. 9601 

et seq.) by establishing certain 

responsibilities for the ATSDR and the 

U.S. Environmental Protection Agency 

(EPA) with regard to hazardous 

substances that are most commonly 

found at facilities on the CERCLA 

National Priorities List (NPL). Among 

these responsibilities is that the 

Administrator of ATSDR prepare 

toxicological profiles for substances 

included on the priority lists of 

hazardous substances. These lists 

identified 275 hazardous substances 

that ATSDR and EPA determined pose 

the most significant potential threat to 

human health. The availability of the 

revised priority list of 275 hazardous 

substances was announced in the 

Federal Register on November 7, 2003 

(68 FR 63098). For prior versions of the 

list of substances see Federal Register

notices dated April 17, 1987 (52 FR 

12866); October 20, 1988 (53 FR 41280); 

October 26, 1989 (54 FR 43619); October 

17, 1990 (55 FR 42067); October 17, 

1991 (56 FR 52166); October 28, 1992 

(57 FR 48801); February 28, 1994 (59 FR 

9486); April 29, 1996 (61 FR 18744); 

November 17, 1997 (62 FR 61332); 

October 21, 1999 (64 FR 56792) and 

October 25, 2001 (66 FR 54014). 

[CERCLA also requires ATSDR to assure 

the initiation of a research program to 

fill data needs associated with the 

substances.]

Section 104(i)(3) of CERCLA [42 

U.S.C. 9604(i)(3)] outlines the content of 

these profiles. Each profile will include 

an examination, summary and 

interpretation of available toxicological 

information and epidemiologic 

evaluations. This information and these 

data are to be used to identify the levels 

of significant human exposure for the 

substance and the associated health 

effects. The profiles must also include a 

determination of whether adequate 

information on the health effects of each 

substance is available or in the process 

of development. When adequate 

information is not available, ATSDR, in 

cooperation with the National 

Toxicology Program (NTP), is required 

to assure the initiation of research to 

determine these health effects. 

Although key studies for each of the 

substances were considered during the 

profile development process, this 

Federal Register notice seeks to solicit 

any additional studies, particularly 

unpublished data and ongoing studies, 

that will be evaluated for possible 

addition to the profiles now or in the 

future. 

The following draft toxicological 

profiles will be made available to the 

public on or about October 18, 2004.

Document Hazardous substance CAS No. 

1. ................... Cyanide .................................................................................................................................................................. 000057–12–5 

Hydrogen cyanide .................................................................................................................................................. 000074–90–8 

Sodium cyanide ...................................................................................................................................................... 000143–33–9 

Potassium cyanide ................................................................................................................................................. 000151–50–8 

2. ................... Dichlorobenzenes ................................................................................................................................................... 025321–22–6 

1, 2-Dichlorobenzene ............................................................................................................................................. 000095–50–1

1,3-Dichlorobenzene .............................................................................................................................................. 00541–73–1 

1,4-Dichlorobenzene .............................................................................................................................................. 00106–46–7 

3. ................... 1, 4-Dioxane * ......................................................................................................................................................... 000123–91–1 

4. ................... Hydrogen Sulfide .................................................................................................................................................... 007783–065–4 

5. ................... 1, 1, 1-Trichloroethane ........................................................................................................................................... 000071–55–6 

6. ................... Vinyl Chloride ......................................................................................................................................................... 000075–01–4 

*denotes new profile. 

All profiles issued as ‘‘Drafts for 

Public Comment’’ represent ATSDR’s 

best efforts to provide important 

toxicological information on priority 

hazardous substances. We are seeking 

public comments and additional 

information that may be used to 

supplement these profiles. ATSDR 

remains committed to providing a 

public comment period for these 

documents as a means to best serve 

public health and our clients.

Georgi Jones, 

Director, Office of Policy, Planning and 

Evaluation, National Center for 

Environmental Health/Agency for Toxic 

Substances and Disease Registry.

[FR Doc. 04–23616 Filed 10–21–04; 8:45 am] 

BILLING CODE 4163–70–P

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Agency for Toxic Substances and 

Disease Registry 

[ATSDR–204] 

Availability of Final Toxicological 

Profiles

AGENCY: Agency for Toxic Substances 

and Disease Registry (ATSDR), 

Department of Health and Human 

Services (HHS).

ACTION: Notice of availability.

SUMMARY: This notice announces the 

availability of one update and four new 

final toxicological profiles, completing 

the 2nd set developed for the 

Department of Energy, prepared by 

ATSDR.

FOR FURTHER INFORMATION CONTACT: Ms. 

Yulandia Jordon, Office of 

Communication, Agency for Toxic 

Substances and Disease Registry, 

Mailstop E–29, 1600 Clifton Road, NE., 

Atlanta, Georgia 30333, telephone 1–

888–422–8737 or (404)498–0261.

SUPPLEMENTARY INFORMATION: These 

toxicological profiles were developed by 

ATSDR for hazardous substances at 

Department of Energy (DOE) waste sites 

under Section 104(i)(3) and (5) of the 

Comprehensive Environmental 

Response, Compensation, and Liability 

Act of 1980 (CERCLA or Superfund). 

This public law directed ATSDR to 

prepare toxicological profiles for 

hazardous substances that are most 

commonly found at facilities on the 

CERCLA National Priorities List (NPL) 

and that pose the most significant 

potential threat to human health, as 

determined by ATSDR and the EPA. 

The current ATSDR priority list of 

hazardous substances at DOE NPL sites 

was announced in the Federal Register

on July 24, 1996 (61 FR 38451). 

Notices (66 FR 53610) and (66 FR 

41243) announcing the availability of 

the draft toxicological profiles for public

Federal Register / Vol. 69, No. 204 / Friday, October 22, 2004 / Notices 62051

review and comment were published in 

the Federal Register on October 23, 

2001, and August 7, 2001, with notice 

of a 90-day public comment period for 

each profile, starting from the actual 

release date. Following the close of the 

comment period, chemical-specific 

comments were addressed, and, where 

appropriate, changes were incorporated 

into each profile. The public comments 

and other data submitted in response to 

the Federal Register notices bear the 

docket control number ATSDR–174 and 

ATSDR–171. This material is available 

for public inspection at the Division of 

Toxicology, Agency for Toxic 

Substances and Disease Registry, 1825 

Century Boulevard, Atlanta, Georgia, 

(not a mailing address) between 8 a.m. 

and 4:30 p.m., Monday through Friday, 

except legal holidays. 

Availability 

This notice announces the availability 

of one update and four new final 

toxicological profiles, comprising the 

2nd set developed for the Department of 

Energy, prepared by ATSDR. The 

following toxicological profiles are now 

available through the U.S. Department 

of Commerce, National Technical 

Information Service (NTIS), 5285 Port 

Royal Road, Springfield, Virginia 22161, 

telephone 1–800–553–6847. There is a 

charge for these profiles as determined 

by NTIS.

SECOND SET OF DOE PROFILES

Toxicological profile NTIS order No. CAS No. 

1. Americium ...................................................................................................................................................... PB2004–104396 7440–35–9 

2. Cesium ........................................................................................................................................................... PB2004–104397 7440–46–2 

3. Cobalt (Update) ............................................................................................................................................. PB2004–104398 7440–48–4 

4. Iodine ............................................................................................................................................................. PB2004–104399 7553–56–2 

5. Strontium ....................................................................................................................................................... PB2004–104400 7440–35–9 

Georgi Jones, 

Director, Office of Policy, Planning, and 

Evaluation, National Center for 

Environmental Health/Agency for Toxic 

Substances and Disease Registry.

[FR Doc. 04–23617 Filed 10–21–04; 8:45 am] 

BILLING CODE 4163–70–P

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Centers for Disease Control and 

Prevention 

Cooperative Agreement for the 

Surveillance, and Prevention of Birth 

Defects 

Announcement Type: New. 

Funding Opportunity Number: RFA 

05006. 

Catalog of Federal Domestic 

Assistance Number: 93.283. 

Application Deadline: December 21, 

2004. 

I. Funding Opportunity Description 

Authority: This program is authorized 

under sections 317(k)(2) of the Public 

Health Service Act [42 U.S.C. 

247b(k)(2)]. 

Purpose: The purpose of the program 

is to promote international surveillance 

and prevention of birth defects. This 

program addresses the ‘‘Healthy People 

2010’’ focus area(s) of Maternal, Infant 

and Child Health. 

Measurable outcomes of the program 

will be in alignment with one of the 

following performance goal(s) for the 

National Center on Birth Defects and 

Developmental Disabilities (NCBDDD): 

(1) Prevent birth defects and 

developmental disabilities (2) improve 

the health and quality of life of 

Americans with disabilities. 

This announcement is only for nonresearch activities supported by CDC. If 

research is proposed, the application 

will not be reviewed. For the definition 

of research, please see the CDC web site 

at the following Internet address: http:/

/www.cdc.gov/od/ads/opspoll1.htm

Activities: Awardee activities for this 

program are as follows: 

• Develop and/or maintain an 

international birth defects database that 

includes data from developed and 

developing countries from different 

areas of the world. 

• Promote and operate an 

international collaboration and data 

clearinghouse among international 

partners and birth defect registries that 

enables international collaborative birth 

defect surveillance, epidemiologic 

assessment, and capacity building. 

• Using such international partners 

and the international birth defects 

database, evaluate, compare and 

confirm patterns and trends of birth 

defects occurrences. 

• Obtain, compile, and publish birth 

defect surveillance data from areas in 

the developed and developing world to 

assess the impact of birth defects. 

• In collaboration with international 

partners, conduct secondary data 

analyses in order to evaluate potential 

birth defect risk factors and identify 

areas in need of epidemiologic 

assessments. 

• Disseminate the birth defect 

surveillance data to member programs, 

partners such as national and 

international organizations, the World 

Health Organization, other health 

agencies, and other interested parties. 

• Evaluate the changes in the 

occurrence of selected adverse 

reproductive outcomes likely to be 

prevented by folic acid (e.g., neural tube 

defects, oral clefts, and certain heart 

defects) in relation to folic acid policies 

that have been instituted in different 

areas of the world, including the 

Americas, Europe, the Middle East, 

Asia, and Africa.

• Promote or develop tools and 

guidelines to assist the development of 

birth defects surveillance activities in 

both developed and developing 

countries. 

In a cooperative agreement, CDC staff 

is substantially involved in the program 

activities, above and beyond routine 

grant monitoring. 

CDC Activities for this program are as 

follows: 

• Assist, if requested, in designing, 

developing, and evaluating 

methodologies and approaches used for 

population-based birth defects 

surveillance. 

• Assist, if requested, in analyzing 

surveillance data related to birth 

defects. 

• Assist, if requested, in providing 

scientific consultation and assistance in 

the study of birth defects and in the 

approaches to study design, 

methodology, and implementation in 

the conduct of secondary data analyses. 

• Assist, if requested, in the 

definition and format of the birth defect 

surveillance reports. 

• Assist, if requested in developing 

tools and guidelines for birth defect 

surveillance. 

II. Award Information 

Type of Award: Cooperative 

Agreement. CDC involvement in this