1

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Manufacturing Use Products

For all Manufacturing 

Use Products

“Only for formulation into an insecticide for the following use(s) [fill blank only 

with those uses that are being supported by MP registrant].”

Formulation into Wettable Powder:

“Not for formulation into Wettable Powder formulations unless they are packaged 

in water soluble bags.”

Outdoor Residential Misting Systems:

If Registrants are not supporting outdoor residential misting systems use for their 

products, the following statement must appear on the MUP label of all liquid or 

wettable powder products:

“Not for formulation into an end use product for use in outdoor residential 

misting systems” 

Formulation into Liquid and Ready to Use Products labeled or intended for 

use on residential indoor surfaces:

All liquid and RTU products labeled for use on indoor surfaces (broadcast, 

baseboard, spot, and crack and crevice) at residential sites must be formulated to 

contain no more than 0.5% of permethrin active ingredient. 

All liquid products (excluding RTU aerosols) labeled for use on indoor surfaces 

must state the following “Not for broadcast use.”

Note to Registrant: The Agency will consider specialized sprays with higher 

Directions for Use
2

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

concentrations, up to 3% ai, which are intended to be injected directly into cracks 

and crevices and behind walls or spaces if the registrants of the products can 

provide justification or data to the Agency which demonstrates that the 

specialized use will result in little to no exposure. 

Formulations into Total Release Foggers labeled for use on residential indoor 

spaces: 

Total release foggers labeled for indoor use at residential sites must be formulated 

to contain no more than 0.58% permethrin active ingredient.

Note to Registrant: The Agency will consider products with higher 

concentrations if the registrants of the products can provide justification or data to 

the Agency which demonstrates that an equivalent ISR of 5.6 μg/cm2, or less, will 

results in a room size of 2000 ft3 or less.

Formulations into Thermal and Cold Foggers “Not for formulation into 

products for commercial indoor use applied with thermal or cold handheld 

foggers.” 

Formulations into products intended for impregnated fabric applications:

“Do not exceed an application rate equivalent to 1.25 grams of a.i. per square 

meter of fabric.” 

One of these statements 

may be added to a label to 

allow reformulation of 

the product for a specific 

“This product may be used to formulate products for specific use(s) not listed on 

the MP label if the formulator, user group, or grower has complied with U.S. EPA 

submission requirements regarding support of such use(s).”

Directions for Use
3

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

use or all additional uses 

supported by a formulator 

or user group

“This product may be used to formulate products for any additional use(s) not 

listed on the MP label if the formulator, user group, or grower has complied with 

U.S. EPA submission requirements regarding support of such use(s).”

Environmental Hazards 

Statements Required by 

the RED and Agency 

Label Policies 

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Do not discharge effluent containing this product into lakes, 

streams, ponds, estuaries, oceans, or other waters unless in accordance with the 

requirements of a National Pollutant Discharge Elimination System (NPDES) 

permit and the permitting authority has been notified in writing prior to discharge. 

Do not discharge effluent containing this product to sewer systems without 

previously notifying the local sewage treatment plant authority. For guidance, 

contact your State Water Board or Regional Office of the EPA.” 

Precautionary Statements

End Use Products Primarily Intended for WPS and Occupational Use (includes commercial pest control operators)

Restricted Use Pesticide 

(For all products used for 

wide area outdoor 

broadcast application 

including agricultural 

crops, golf courses, 

nurseries, and sod farms)

“RESTRICTED USE PESTICIDE Due to Toxicity to Fish and Aquatic 

Organisms. For retail sale to and use only by certified applicators or persons 

under the direct supervision and only for those uses covered by the certified 

applicator’s certification.” 

Top front panel of label
4

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

PPE Requirements 

Established by the RED1

For Wettable Powder, 

Liquid, and Dry Flowable 

Concentrates (Dry 

Flowables not registered 

at this time, but may be 

registered in the future.)

Note: If the use of ULV 

foggers or fog or mist 

generators is not 

permitted or not feasible 

for the end-use product, 

the statement requiring 

special PPE and 

respirators for those uses 

may be omitted.

“Personal Protective Equipment (PPE)

Some materials that are chemical-resistant to this product are (registrant inserts 

correct chemical-resistant material). If you want more options, follow the 

instructions for category@ [registrant inserts A,B,C,D,E,F,G, or H] on an EPA 

chemical-resistance category selection chart.”

“Applicators using ULV cold foggers or fog/mist generators in indoor spaces 

must wear: 

> Coveralls over long-sleeved shirt and long pants,

> Chemical-resistant gloves,

> Chemical resistant footwear plus socks, and

> Chemical-resistant headgear, if overhead exposure.”

“Applicators using ULV cold foggers and/or fog/mist generators in outdoor 

spaces must wear: 

> Long-sleeve shirt and long pants,

> Shoes plus socks, and

> Chemical-resistant gloves.”

Note to Registrant: If cold fogger and/or fog/mist generator use is prohibited on 

the label, the above PPE for these uses may be omitted. 

“All other mixers, loaders, applicators, and other handlers must wear: 

> Long-sleeve shirt and long pants,

> Shoes plus socks,

> Chemical-resistant gloves for all handlers except for applicators using 

motorized ground equipment, pilots, and flaggers, 

> Chemical-resistant apron for mixers/loaders, persons cleaning equipment, and 

persons exposed to the concentrate and for handlers performing animal dip 

Immediately following/below 

Precautionary Statements: Hazards to Humans and 

Domestic Animals
5

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

applications.” 

“See engineering controls for additional requirements.”

Instruction to Registrant: Drop the “N” type prefilter from the respirator 

statement, if the pesticide product contains, or is used with, oil.

PPE Requirements 

Established by the RED1

For Granular 

Formulations

“Personal Protective Equipment (PPE)

Some materials that are chemical-resistant to this product are” (registrant inserts 

correct chemical-resistant material). “If you want more options, follow the 

instructions for category” [registrant inserts A,B,C,D,E,F,G,or H] “on an EPA 

chemical-resistance category selection chart.”

“All loaders , applicators, and other handlers must wear: 

> Long-sleeve shirt and long pants,

> Shoes plus socks, and

> Chemical-resistant gloves for all handlers except for applicators using 

motorized ground equipment, pilots, and flaggers.”

“See engineering controls for more requirements.” 

Immediately following/below 

Precautionary Statements: Hazards to Humans and 

Domestic Animals
6

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

PPE Requirements 

Established by the RED1

For Dust 

Formulations

Note: if application with 

aerial or motorized 

ground equipment is not 

feasible with the labeled 

uses, the prohibition 

statement may be 

eliminated.

“Personal Protective Equipment (PPE)

Some materials that are chemical-resistant to this product are (registrant inserts 

correct chemical-resistant material). If you want more options, follow the 

instructions for category [registrant inserts A, B, C, D, E, F, G, or H] on an EPA 

chemical-resistance category selection chart.”

“Loaders, applicators, and other handlers must wear:

> Long-sleeve shirt and long pants,

> Shoes plus socks,

> Chemical-resistant gloves, and

> A NIOSH-approved respirator with:

-- a dust/mist filter with MSHA/NIOSH approval number prefix TC-21C or 

-- any N, R, P, or HE filter.” 

“Application with aerial or motorized ground equipment is prohibited.”

Immediately following/below 

Precautionary Statements: Hazards to Humans and 

Domestic Animals

Engineering controls for 

Wettable Powder 

Formulations

Note if aerial application 

is not permitted or not 

feasible for the end-use 

product, the engineering 

control statements 

referring to pilots may be 

omitted.

“Engineering controls

Water-soluble packets when used correctly qualify as a closed mixing/loading 

system under the Worker Protection Standard for Agricultural Pesticides [40 CFR 

170.240(d)(4)]. Mixers and loaders using water-soluble packets must:

-- wear the personal protective equipment required in the PPE section of this 

labeling for mixers and loaders, and 

-- be provided and must have immediately available for use in an emergency, such 

as a broken package, spill, or equipment breakdown chemical resistant footwear 

and dust/mist respirators. 

Pilots must use an enclosed cockpit that meets the requirements listed in the 

Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 

170.240(d)(6)].”

Precautionary Statements: Hazards to Humans and 

Domestic Animals immediately below PPE

Requirements 
7

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Engineering controls for 

Liquids, Dry Flowable, 

and Granular 

Formulations

Note if aerial application 

is not permitted or not 

feasible for the end-use 

product, the engineering 

control statements

referring to pilots may be 

omitted.

“Pilots must use an enclosed cockpit that meet the requirements listed in the 

Worker Protection Standard (WPS) for agricultural pesticides [40 CFR 

170.240(d)(6)].”

Precautionary Statements: Hazards to Humans and 

Domestic Animals immediately below PPE 

requirements

User Safety Requirements “Follow manufacturer's instructions for cleaning/maintaining PPE. If no such 

instructions for washables exist, use detergent and hot water. Keep and wash PPE 

separately from other laundry.

Discard clothing and other absorbent materials that have been drenched (except as 

required by directions for use) or heavily contaminated with this product’s 

concentrate. Do not reuse them.”

Precautionary Statements under: Hazards to Humans 

and Domestic Animals immediately following 

Engineering Controls

User Safety 

Recommendations

“USER SAFETY RECOMMENDATIONS”

“Users should wash hands before eating, drinking, chewing gum, using tobacco, 

or using the toilet.”

“Users should remove clothing/PPE immediately if pesticide gets inside. Then 

wash thoroughly and put on clean clothing.”

“Users should remove PPE immediately after handling this product. Wash the 

Precautionary Statements under: Hazards to Humans 

and Domestic Animals immediately following User 

Safety Requirements

(Must be placed in a box.)
8

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

outside of gloves before removing. As soon as possible, wash thoroughly and 

change into clean clothing.”

Precautionary statement 

for all permethrin canine 

spot on products (i.e. 

45/65% permethrin 

concentrations spot-on 

products for dogs)

Note to registrant:

All cat warning labels will be placed within a shaded box within the 

Precautionary Statements on the label. The coloring of the box and text will be 

such to provide a contrasting color to other label text. The shaded box must 

contain the following.

“DO NOT USE ON CATS. May be toxic or potentially fatal if applied to or 

ingested by cats. Accidental application to cats and/or grooming a recently 

treated dog may result in tremors and/or uncoordinated muscle movements. If 

this occurs, immediate veterinary care should be provided.”

Each label must include at least one cat slash icon. This icon may be in the 

shaded box or in other areas on the label. 

Each individual tube must be labeled with the “DO NOT USE ON CATS’ 

statement or cat slash icon. 

Include the following statement prominently on the front panel of product 

packaging (in bold), “DO NOT USE ON CATS”

Precautionary Statements

Environmental Hazards 

For Agricultural

Products with any 

Outdoor Use, except wide 

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Do not apply directly to water, or to areas where surface water is 

present or to intertidal areas below the mean water mark. Do not apply when 

weather conditions favor drift from treated areas. Drift and runoff from treated 

Precautionary Statements immediately following the 

User Safety Recommendations
9

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

area mosquito adulticide 

application.

(See EHS for nonagricultural outdoor use 

and mosquito adulticide 

applications below.)

areas may be hazardous to aquatic organisms in neighboring areas. Do not 

contaminate water when disposing of equipment wash waters.”

“Under some conditions, it may also have a potential for transport into surface 

water in runoff (primarily adsorbed to suspended soil particles), for several

months or more after application. These include poorly draining or wet soils with 

readily visible slopes toward adjacent surface waters, frequently flooded areas, 

and areas overlying extremely shallow groundwater, areas with in-field canals or 

ditches that drain to surface water, areas not separated from adjacent surface 

waters with vegetated filter strips, and areas over-lying tile drainage systems that 

drain to surface waters.”

“This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

For commercial, industrial, and institutional use products packaged in 

containers equal or greater than 5 gallons or 50 pounds, add the following 

statement:

“Do not discharge effluent containing this product into lakes, streams, ponds, 

estuaries, oceans, or other waters unless in accordance with the requirements of a 

National Pollutant Discharge Elimination System (NPDES) permit and the 

permitting authority has been notified in writing prior to discharge. Do not 

discharge effluent containing this product to sewer systems without previously 

notifying the local sewage treatment plant authority. For guidance contact your 

State Water Board or Regional Office of the EPA.” 
10

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Environmental hazard 

statements on Liquid 

Concentrate consumer

outdoor products (e.g., 

liquids mixed with water 

by the user for a tank 

sprayer or hose-end 

attachment)

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

Rinsing application equipment over the treated area will help avoid run off to 

water bodies or drainage systems.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Environmental hazard 

statements on Broadcast 

Granular consumer 

outdoor products (e.g., 

ready-to-use granular 

products which may be 

combined with fertilizers 

and broadcast applied

with a drop or rotary 

spreader)

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area. 

Sweeping any product that lands on a driveway, sidewalk, or street, back onto the 

treated area of the lawn or garden will help to prevent run off to water bodies or 

drainage systems.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Environmental hazard 

statements on Dusts 

consumer outdoor 

products (e.g., for garden 

or ornamental)

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

Environmental Hazard Statement
11

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental hazard 

statements on Liquid 

Ready-to-Use (except 

aerosols and foggers) 

consumer outdoor 

products 

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Environmental hazard 

statements on aerosol 

consumer (including 

foggers) outdoor products

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Do not apply directly to water, or to areas where surface water is 

present or to intertidal areas below the mean water mark. Do not apply when 

weather conditions favor drift from treated areas. Drift and runoff from treated 

areas may be hazardous to aquatic organisms in neighboring areas. .”

“This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental 

Hazards Statements for 

products labeled solely 

for use as a wide area 

mosquito adulticide:

(PR Notice 2005-1 

recommends separating 

“ENVIRONMENTAL HAZARDS”

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Runoff from treated areas or deposition of spray droplets into a 

body of water may be hazardous to fish and aquatic invertebrates.”

“Before making the first application in a season, it is advisable to consult with the 

state or tribal agency with primary responsibility for pesticide regulation to 

Precautionary Statements under Environmental 

Hazards
12

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

labels intended for wide 

area mosquito adulticide 

applications.)

determine if other regulatory requirements exist.”

“Do not apply over bodies of water (lakes, rivers, permanent streams, natural 

ponds, commercial fish ponds, swamps, marshes or estuaries), except when 

necessary to target areas where adult mosquitoes are present, and weather 

conditions will facilitate movement of applied material away from the water in 

order to minimize incidental deposition into the water body. Do not contaminate 

bodies of water when disposing of equipment rinsate or washwaters.”

Environmental 

Hazards Statements for 

products labeled as a 

wide area mosquito 

adulticide and is labeled 

for other consumer 

outdoor uses as well:

(PR Notice 2005-1 

recommends separating 

labels intended for wide 

area mosquito 

adulticiding applications.)

“ENVIRONMENTAL HAZARDS for TERRESTRIAL APPLICATIONS”

Refer to appropriate consumer outdoor environmental hazard statements above. 

“ENVIRONMENTAL HAZARDS for WIDE AREA MOSQUITO 

ADULTICIDE APPLICATIONS”

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Runoff from treated areas or deposition of spray droplets into a 

body of water may be hazardous to fish and aquatic invertebrates.”

“When applying as a wide area mosquito adulticide, before making the first 

application in a season, it is advisable to consult with the state or tribal agency 

with primary responsibility for pesticide regulation to determine if other 

regulatory requirements exist.”

“When applying as a wide area mosquito adulticide, do not apply over bodies of 

water (lakes, rivers, permanent streams, natural ponds, commercial fish ponds, 

swamps, marshes or estuaries), except when necessary to target areas where adult 

mosquitoes are present, and weather conditions will facilitate movement of 

applied material away from the water in order to minimize incidental deposition 

Precautionary Statements under Environmental 

Hazards
13

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

into the water body.” 

Environmental Hazards 

(For Products labeled 

only for Indoor Use 

including ready to use 

impregnated materials 

(e.g. products used on 

domestic animals like flea 

collars and ear tags)

No Environmental Hazard Statement is required. Precautionary Statements immediately following the 

User Safety Recommendations

Restricted-Entry Interval 

for products with 

directions for use within 

scope of the Worker 

Protection Standard for 

Agricultural Pesticides 

(WPS)

“Do not enter or allow worker entry into treated areas during the restricted entry 

interval (REI) of 12 hours.” 

Directions for Use, Agricultural Use Requirements 

Box

Early Entry Personal 

Protective Equipment for 

products with directions 

for use within the scope 

of the WPS

“PPE required for early entry to treated areas that is permitted under the Worker 

Protection Standard and that involves contact with anything that has been treated, 

such as plants, soil, or water, is:

* coveralls,

* shoes plus socks

* chemical-resistant gloves made of any waterproof material”

Direction for Use

Agricultural Use Requirements box

Entry Restrictions for 

products having nonWPS uses applied as 

spray 

Entry Restriction for products applied as a surface spray (does not apply to 

products applied directly to domestic animals): 

“Do not enter or allow others to enter until sprays have dried.”

If no WPS uses on the product label, place the 

appropriate statement in the Directions for Use 

Under General Precautions and Restrictions. If the 

product also contains WPS uses, then create a NonAgricultural Use Requirements box as directed in 
14

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Note: This excludes 

products labeled for use 

when people are present 

(e.g. outdoor residential 

misting systems, fabric 

treatments and pet 

applications)

Entry Restriction for products applied as a space spray or fog:

“Do not enter or allow others to enter until vapors, mists, and aerosols have 

dispersed, and the treated area has been thoroughly ventilated.”

PR Notice 93-7 and place the appropriate statement 

inside that box. 

Entry Restrictions for 

products having nonWPS uses applied as a 

stationary fogger

“For 4 hours following applications, do not allow any person to reenter treated 

areas.” 

Entry Restrictions for 

products having nonWPS uses applied as 

granular or dusts

“Do not enter or allow others to enter until dusts have settled.”

For products with use instructions requiring watering in after application:

“Do not enter or allow others to enter the treated area until dusts have settled. If 

soil incorporation is required after the application, do not enter or allow others to 

enter the treated area (except those persons involved in the incorporation) until the 

incorporation is complete. If the incorporation is accomplished by watering-in, do 

not enter or allow others to enter the treated area until the surface is dry after the 

watering-in.”

Entry Restrictions for 

products labeled solely 

for use when people are 

present (e.g. fabric 

No entry restrictions are required. See below under “Use Restrictions” for further 

requirements. 
15

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

treatments, livestock, and 

pet applications)

Entry Restrictions for 

products labeled for use 

when people are present 

(e.g. fabric treatments, 

livestock, and pet 

applications) and for use 

on other sites as a surface 

or space spray.

Entry Restriction for products applied dry:

“Do not enter or allow others to enter until dusts have settled.”

Entry Restriction for products applied as a surface spray (does not apply to 

products applied directly to domestic animals): 

“Except when (insert application method or site that allows people to be present), 

do not enter or allow others to enter treated area until sprays have dried.”

Entry Restriction for products applied as a space spray or as a fog:

“Except when (insert application method or site that allows people to be present), 

do not enter or allow others to enter until vapors, mists, and aerosols have 

dispersed, and the treated area has been thoroughly ventilated.”

Note to Registrant: An example is as follows: Except when applying to pets or 

livestock, do not enter or allow others to enter until sprays have dried.

Total release foggers labeled for indoor use must contain the following entry 

restriction:

“Wait two (2) hours after application, then open windows, vents and doors for 

two hours. If an odor is still detected additional ventilation is required.” 

Note to registrant- If you have any information that justifies a change in the 

duration after application (2 hours), submit the information to the Agency. 
16

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

General Application 

Restrictions for products 

with WPS or non-WPS 

uses on the label

Note: This excludes 

products that contain any 

directions for when 

people are permitted to be 

present in the treated area 

(e.g. wide-area mosquito 

adulticide applications, 

fabric treatments, and 

applications to livestock 

and pets) 

“Do not apply this product in a way that will contact workers or other persons, 

either directly or through drift.” 

“Only protected handlers may be in the area during application.”

Place in the Direction for Use.

General Application 

Restrictions for products 

with WPS and non-WPS 

uses on the label AND 

are labeled for use when 

people may be present 

(e.g. . wide-area mosquito 

adulticide applications, 

fabric treatments, and 

applications to livestock 

and pets)

“Except when” (insert application method or site that allows people to be present) 

“do not apply this product in a way that will contact workers or other persons, 

either directly or through drift.” 

“Except when” (insert application method or site that allows people to be present) 

“only protected handlers may be in the area during application.”

“Do not breathe dusts, vapors, or spray mist.”

For applications to food/feed handling and service areas:

“Do not apply when food is present.”

“Do not use in food areas of food handling establishments, restaurants, or other 

areas where food is commercially prepared or processed. Do not use in serving 

Place in the Direction for Use. 
17

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

areas while food is exposed or facility is in operation. Serving areas are areas 

where prepared foods are served, such as dining rooms, but excluding areas where 

foods may be prepared or held. In the home, all food processing surfaces and 

utensils should be covered during treatment or thoroughly washed before use. 

Exposed food should be covered or removed.”

General Application 

Restrictions for products 

solely labeled for use 

when people may be 

present (e.g. wide-area 

mosquito adulticide 

applications, fabric 

treatments, and 

applications to livestock 

and pets)

No general application restrictions are required. See below under “Use 

Restrictions” for further requirements. 

Place in the Direction for Use. 

General Application 

Restrictions for all 

products that do not 

contain directions for use 

in drains or sewers

Products labeled for use around or near floor drains must contain the 

following statement. 

“Application is prohibited directly into sewers or drains, or to any area like a 

gutter where drainage to sewers, storm drains, water bodies, or aquatic habitat can 

occur. Do not allow the product to enter any drain during or after application.”

Directions for Use

General Application 

Restrictions for all 

products that contain 

directions for use in 

drains or sewers

“Do not apply directly to sewers or drains, or to any area like a gutter where 

drainage to sewers, storm drains, water bodies, or aquatic habitat can occur, 

except as directed by this label.”

Directions for Use

Use-Specific Application 

Restrictions 

Products labeled for use in mushroom houses:

“Use of high pressure hand wand prohibited in mushroom houses.” 

Directions for Use
18

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Products labeled for use in dairy barns:

“When used in dairy barns or facilities: Close milk bulk tank lids to prevent 

contamination from

Products labeled for or intended for use as directed surface sprays for use on 

residential indoor surfaces (excludes Ready to Use products and Total 

Release Foggers): 

“Do not apply as a broadcast or spot-treatment to indoor surfaces at residential 

sites, including nurseries, day care centers, schools, hospitals, and nursing 

homes.” 

General Outdoor Surface and Space Sprays (except for outdoor fogging 

devices):

“All outdoor applications must be limited to spot or crack-and-crevice treatments 

only, except for the following permitted uses:

(1) Treatment to soil or vegetation around structures;

(2) Applications to lawns, turf, and other vegetation;

(3) Applications to building foundations, up to a maximum height of 3 feet. 

Other than applications to building foundations, all outdoor applications to 

impervious surfaces such as sidewalks, driveways, patios, porches and structural 

surfaces (such as windows, doors, and eaves) are limited to spot and crack-andcrevice applications, only.”

Formulation-Specific 

Application Restrictions 

Requirements for all Formulations with existing aircraft uses:

“Do not use in aircraft cabins .” 

Requirements for Granular Formulations labeled or intended for outdoor 
19

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

residential uses: 

“Apply this product directly to the lawn or garden area. Water treated area as 

directed on this label. Do not water to the point of run-off.”

“Do not make applications during rain.”

Requirements for Liquid, Dust, and Ready to Use Formulations products 

labeled or intended for outdoor residential uses: 

“Do not water the treated area to the point of run-off.”

“Do not make applications during rain.”

Products formulated as Dusts:

“Use of handheld power duster equipment is prohibited.”

Products formulated into cold or thermal foggers for commercial use:

“Use in a handheld cold or thermal foggeris prohibited.”

Use-Specific Rate 

Restrictions – NonAgricultural

Liquid and Ready to Use Products labeled or intended for use on residential 

indoor surfaces (excludes Ready to Use products and Total Release 

Foggers)::

All liquid and RTU products labeled for use on indoor surfaces (broadcast, 

baseboard, spot, and crack and crevice) at residential sites must be formulated to 

contain no more than 0.5% of permethrin active ingredient. 

Directions for Use under Application Instructions
20

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

All liquid products (excluding RTU aerosols) labeled for use on indoor surfaces 

must state the following “Not for broadcast use.”

Note to Registrant: The Agency will consider specialized sprays with higher 

concentrations, up to 3% ai, which are intended to be injected directly into cracks 

and crevices and behind walls or spaces if the registrants of the products can 

provide justification or data to the Agency which demonstrates that the 

specialized use will result in little to no exposure. 

Total Release Foggers labeled for use on residential indoor spaces: 

Total release foggers labeled for indoor use at residential sites must be formulated 

to contain no more than 0.58% permethrin active ingredient.

Note to Registrant: The Agency will consider products with higher 

concentrations if the registrants of the products can provide justification or data to 

the Agency which demonstrates that an equivalent ISR of 5.6 μg/cm2, or less, will 

results in a room size of 2000 ft3 or less. 

Use-Specific Rate 

Restrictions –

Agricultural 

(Note: The maximum 

application rate and 

maximum seasonal rates 

specified in this table 

must be listed as pounds 

Amend all agricultural use product labels with use on pine seed orchards to 

reflect the following use directions:

 Seedbug and coneworm: 

Ground (low and high volume applications): Use 8-16 fuid oz of 

product/treated acre (0.2-0.4 lb ai/treated acre) using a final carrier solution 

of 25-400 gallons depending on the type of sprayer system being used. 

Make up to three applications per season. 

Air: Use 24 fluid oz of product/treated acre (0.6 lb ai/treated acre). Apply in 

Directions for Use under Application Instructions
21

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

or gallons of formulated 

product per acre/square 

ft/ppm/cubic feet etc., not 

just as pounds active 

ingredient)

See Appendix A for all 

rate restrictions.

a minimum of 5 gallons of finished spray per acre. Apply once per season.

Amend all agricultural use product labels with the following crops to reflect 

the following maximum application rate, retreatment intervals, and seasonal 

maximum application rates: 

Crop Maximum rate 

per application 

(lb ai/A)

Retreatment 

interval

(Days)

Seasonal 

Maximum 

Application 

Rate (lb ai/A)

Alfalfa 0.2 30 0.2 per cutting

Almonds 0.25 10 0.75

Hazelnuts 0.25 10 0.75

Pistachios 0.3 10 0.9

Walnuts 0.25 10 0.75

Apples 0.25 10 0.5

Pears 0.25

(0.4 dormant only)

10 0.65

Cherries 0.2 10 0.6

Peaches/

Nectarines

0.25 10 0.75

Artichokes 0.3 10 0.9

Asparagus 0.1 7 0.4

Avocados 0.2 7 0.8

Broccoli 0.2 5 0.8

Brussels Sprouts 0.1 5 0.4

Cabbage 0.2 5 0.4 (0.8 in HI)

Cauliflower 0.1 5 0.4 (0.6 in HI)

Cantaloupes 0.2 7 0.8 (1.2 in HI)
22

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Cucumbers 0.2 7 1.2

Pumpkins 0.2 7 1.2

Squash (summer, 

winter)

0.2 7 1.2

Watermelon 0.2 7 1.2

Eggplant 0.15 7 0.6 (1.0 in HI)

Peppers, bell 0.2 5 0.8

Tomatoes 0.2 7 0.6 (0.8 in HI)

Celery 0.2 7 1.0 (1.2 in HI)

Lettuce 0.2 7 0.8 (1.2 in HI)

Spinach 0.2 3 0.6

Collards 0.15 3 0.45

Greens, Turnip 0.15 3 0.45

Corn, Field 0.15 7 0.45

Sweet Corn 0.2 3 0.8

Garlic 0.2 10 0.8

Onions 0.3 7 1.0

Horseradish 0.15 10 0.45

Papaya 0.15 10 0.75

Potatoes 0.2 10 0.8

Soybeans 0.2 10 0.4

Use-Specific Application 

Restrictions for all liquid 

and wettable powder 

labels

Outdoor residential 

Misting System

requirement

Products not labeled or intended for use in outdoor residential misting 

systems must contain the following statement: 

“Not for use in outdoor residential misting systems.”

Products labeled or intended for use in outdoor residential misting systems 

must contain the following statements: 

Directions for Use under General Precautions and 

Restrictions and/or Application Instructions
23

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Note to registrant: also 

express this application 

rate as pounds or gallons 

of end-use product 

formulation.

“Directions for use in outdoor residential misting systems:

When using this product installers and service technicians must comply with the 

license, certification, or registration requirements of the state(s), tribe(s), or local 

authority(ies) where they are installed.” 

“Do not use in an evaporative cooling system.”

“Direct nozzles to spray towards the target area and away from swimming pools, 

water bodies, or eating and cooking areas.” 

“Do not set nozzles to direct mist near outside air condition systems or other 

home air intakes.”

“If used in a system with a reservoir tank for the end use dilution, the system 

reservoir tank must be locked. Securely attach the end use pesticide label and a 

dilution statement to the system reservoir tank in a weather protected area or 

plastic sleeve. The dilution statement must be phrased as follows: this container 

holds __ parts [product name] to __ parts water”

“If used in a direct injection system, the pesticide container must be locked. 

Securely attach the end use label to the pesticide container in a weather protected 

area or plastic sleeve.” (These instructions not applicable to wettable powder 

products). 

“If the system works on an automatic timer, set the timing for application when 

people, pets, and/or food are unlikely to be present.”
24

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

“If the system works when a person operates a remote activation device, then 

application of this pesticide when people, pets, and/or food are present is 

prohibited.”

“Contact the system manufacture for guidance or assistance to ensure compliance 

with the following requirement: 

This product may only be used in systems that have been calibrated to apply no 

more than the maximum application rate of 0.25 grams per 1000 cubic feet per 

day.” 

Use-Specific Application 

Restrictions for all liquid 

and wettable powder 

labels

Indoor Misting Systems 

Used in Commercial 

Barns, Stables, and 

Animal Quarters

“Directions for use in commercial animal premise automatic misting 

systems”

“Not for use in outdoor residential misting systems (indoor or outdoor).”

“Do not apply this product in barns or stables where animals intended for 

slaughter or human consumption will be maintained.”

“Do not apply when food, feed, or water is present.”

“Do not apply directly to animals.”

“When using this product, installers and service technicians must comply with the 

license, certification, or registration requirements of the state(s), tribe(s), or local 

authority(ies) where they are installed.” 

“When applying via a remote activation device, do not apply when people and 

pets are present. If possible, when applying via automatic timer, set the timing 

for application when people and pets are unlikely to be present.”

Directions for Use under General Precautions and 

Restrictions and/or Application Instructions
25

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

“Direct nozzles to spray towards the target area and away from areas where 

people are typically present.”

“Do not use in an evaporative cooling system.”

“Do not use in misters located within 3 feet of air vents, air conditioner units, or 

windows.”

“If used in a system with a reservoir tank for the end use dilution, the system 

reservoir tank must be locked. Securely attach the end use pesticide label and a 

dilution statement to the system reservoir tank in a weather protected area or 

plastic sleeve. The dilution statement must be phrased as follows: this container 

holds __ parts [product name] to __ parts water”

“If used in a direct injection system, the pesticide container must be locked. 

Securely attach the end use label to the pesticide container in a weather protected 

area or plastic sleeve.” (These instructions not applicable to wettable powder 

products). 

“This product must only be used in systems that have been calibrated to apply no 

more than the maximum application rate of” [insert product application rate]. 

Note to registrant: Also express this application rate as pounds or gallons of 

end-use product formulation.

Use-Specific Application 

Restrictions for all liquid 

and wettable powder 

labels

Pre-construction 

Termiticide 

Products labeled for preconstruction termiticide applications:

“The treatment site must be covered prior to a rain event in order to prevent runoff of the pesticide into non-target areas. 

The applicator must either cover the soil him/herself or provide written 

notification of the above requirement to the contractor on site and to the person 

Directions for Use
26

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Applications commissioning the application (if different than the contractor). If notice is 

provided to the contractor or the person commissioning the application, then they 

are responsible under FIFRA to ensure that: 1) if the concrete slab cannot be 

poured over the treated soil within 24 hours of application the treated soil is 

covered with a waterproof covering (such as polyethylene sheeting), and 2) the 

treated soil is covered if precipitation is predicted to occur before the concrete 

slab is scheduled to be poured.”

“Do not treat soil that is water-saturated or frozen.”

“Do not treat when raining.”

“Do not allow treatment to runoff from the target area.”

“Do not apply within 10 feet of storm drains. Do not apply within 25 feet of 

aquatic habitats (such as, but not limited to, lakes; reservoirs; rivers; permanent 

streams; marshes or ponds; estuaries; and commercial fish farm ponds).” 

“Do not make on-grade applications when sustained wind speeds are above 10 

mph (at application site) at nozzle end height.”

Products with use 

instructions for use as a 

wide area mosquito

adulticide 

(PR Notice 2005-1 

recommends that separate 

registrations be issued for 

products with these use 

patterns.) 

Amend label instruction to reflect the following:

 Recommendations and requirements specified in Pesticide Registration 

Notice 2005-1;

 Remove 100 foot buffer zone use restriction from the product label;

 Maximum application rate 0.007 lb ai/A; and

 Remove the following restriction from all wide area mosquito adulticide 

products: "Do not spray on or over pasturelands.

Directions for Use under General Precautions and 

Restrictions and/or Application Instructions
27

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

In addition, labels must be amended to include the following statements: 

“For use by federal, state, tribal, or local government officials responsible for 

public health or vector control, or by persons certified in the appropriate category 

or otherwise authorized by the state or tribal lead pesticide regulatory agency to 

perform adult mosquito control applications, or by persons under their direct 

supervision.”

“Do not retreat site more than once in 3 days. Do not exceed 25 applications at 

0.007 pounds of permethrin per acre or 0.18 pounds of permethrin per acre in any 

given season. More frequent treatments may be made to prevent or control a 

threat to public and/or animal health determined by a state, tribal or local health or 

vector control agency on the basis of documented evidence of disease causing 

agents in vector mosquitoes or the occurrence of mosquito-borne diseases in 

animal or human populations, or if specifically approved by the state or tribe 

during a natural disaster recovery effort.”

“Apply when wind speed is greater than 1 mph.”

“Do not apply by fixed wing aircraft at a height less than 100 feet, or by 

helicopter at a height less than 75 feet unless specifically approved by the state or 

tribe based on public health needs.” 

“Aerial Application made at ≤200 above ground elevation:

Spray equipment must be adjusted so that the volume median diameter product is 

less than 60 microns (Dv 0.5 < 60 um) and that 90% of the spray is contained in 

droplets smaller than 100 microns (Dv 0.9 < 100 microns). The effects of flight 

speed and, for non-rotary nozzles, nozzle angle on the droplet size spectrum must 
28

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

be considered. Directions from the equipment manufacturer or vendor, pesticide 

registrant or a test facility using a wind tunnel and laser-based measurement 

instrument must be used to adjust equipment to produce acceptable droplet size 

spectra. Application equipment must be tested at least annually to confirm that 

pressure at the nozzle and nozzle flow rate(s) are properly calibrated.”

“Aerial Application made at >200 above ground elevation:

Spray equipment must be adjusted so that the volume median diameter product is 

less than 70 microns (Dv 0.5 < 70 um) and that 90% of the spray is contained in 

droplets smaller than 145 microns (Dv 0.9 < 145 microns). The effects of flight 

speed and, for non-rotary nozzles, nozzle angle on the droplet size spectrum must 

be considered. Directions from the equipment manufacturer or vendor, pesticide 

registrant or a test facility using a wind tunnel and laser-based measurement 

instrument must be used to adjust equipment to produce acceptable droplet size 

spectra. Application equipment must be tested at least annually to confirm that 

pressure at the nozzle and nozzle flow rate(s) are properly calibrated.”

“Ground-based application:

Spray equipment must be adjusted so that the volume median diameter is less than 

30 microns (Dv 0.5 < 30 um) and that 90% of the spray is contained in droplets 

smaller than 50 microns (Dv 0.9 < 50 um). Directions from the equipment 

manufacturer or vendor, pesticide registrant or a test facility using a laxer-based 

measurement instrument must be used to adjust equipment to produce acceptable 

droplet size spectra. Application equipment must be tested at least annually to 

confirm that pressure at the nozzle and nozzle flow rate(s) are properly 

calibrated.”

Buffer Zone 

Requirements for 

Agricultural Products

BUFFER ZONES

Vegetative Buffer Strip

Directions for Use under General Precautions and 

Restrictions and/or Application Instructions
29

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

“Construct and maintain a minimum 10-foot-wide vegetative filter strip of grass 

or other permanent vegetation between the field edge and down gradient aquatic 

habitat (such as, but not limited to, lakes; reservoirs; rivers; permanent streams; 

marshes or natural ponds; estuaries; and commercial fish farm ponds).” 

“Only apply products containing permethrin onto fields where a maintained 

vegetative buffer strip of at least 10 feet exists between the field and down 

gradient aquatic habitat.” 

For guidance, refer to the following publication for information on constructing 

and maintaining effective buffers:

Conservation Buffers to Reduce Pesticide Losses. Natural Resources 

Conservation Services. USDA, NRCS. 2000. Fort Worth, Texas. 21 pp.

http://www.in.nrcs.usda.gov/technical/agronomy/newconbuf.pdf

Buffer Zone for Ground Application (groundboom, overhead chemigation, 

or airblast)

“Do not apply within 25 feet of aquatic habitats (such as, but not limited to, lakes, 

reservoirs, rivers, streams, marshes, natural ponds, estuaries, and commercial fish 

ponds).” 

Buffer Zone for ULV Aerial Application

“Do not apply within 450 feet of aquatic habitats (such as, but not limited to, 

lakes, reservoirs, rivers, streams, marshes, natural ponds, estuaries, and 

commercial fish ponds).” 

Buffer Zone for Non-ULV Aerial Application

“Do not apply within 150 feet of aquatic habitats (such as, but not limited to, 

lakes, reservoirs, rivers, streams, marshes, natural ponds, estuaries, and 

commercial fish ponds).” 
30

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

Spray Drift Requirements

for Agricultural Products

Spray Drift Requirements:

Wind Direction and Speed

“Only apply this product if the wind direction favors on-target deposition.” 

“Do not apply when the wind velocity exceeds 15 mph.” 

Temperature Inversion

“Do not make aerial or ground applications into temperature inversions.” 

“Inversions are characterized by stable air and increasing temperatures with 

height above the ground. Mist or fog may indicate the presence of an inversion in 

humid areas. The applicator may detect the presence of an inversion by 

producing smoke and observing a smoke layer near the ground surface.”

Droplet Size

“Use only Medium or coarser spray nozzles (for ground and non-ULV aerial 

application) according to ASAE (S572) definition for standard nozzles. In 

conditions of low humidity and high temperatures, applicators should use a 

coarser droplet size.” 

Additional Requirements for Ground Applications

“Wind speed must be measured adjacent to the application site on the upwind 

side, immediately prior to application.” 

“For ground boom applications, apply using a nozzle height of no more than 4 

Directions for Use under Spray Drift Requirements. 
31

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

feet above the ground or crop canopy.” 

“For airblast applications, turn off outward pointing nozzles at row ends and when 

spraying the outer two rows. To minimize spray loss over the top in orchard 

applications, spray must be directed into the canopy.” 

Additional Requirements for Aerial Applications

“The spray boom should be mounted on the aircraft as to minimize drift caused by 

wingtip or rotor vortices. The minimum practical boom length should be used 

and must not exceed 75% of the wing span or 80% rotor diameter.” 

“Flight speed and nozzle orientation must be considered in determining droplet 

size.”

“Spray must be released at the lowest height consistent with pest control and 

flight safety. Do not release spray at a height greater than 10 feet above the crop 

canopy unless a greater height is required for aircraft safety.” 

“When applications are made with a cross-wind, the swath will be displaced 

downwind. The applicator must compensate for this displacement at the 

downwind edge of the application area by adjusting the path of the aircraft 

upwind.”

End Use Products Primarily Intended for Residential Use

Environmental hazard 

statements on Liquid 

Concentrate consumer 

outdoor products (e.g., 

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

Environmental Hazard Statement
32

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

liquids mixed with water 

by the user for a tank 

sprayer or hose-end 

attachment)

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

Rinsing application equipment over the treated area will help avoid run off to 

water bodies or drainage systems.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental hazard 

statements on Broadcast 

Granular consumer 

outdoor products (e.g., 

ready-to-use granular 

products which may be 

combined with fertilizers 

and broadcast applied 

with a drop or rotary 

spreader)

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area. 

Sweeping any product that lands on a driveway, sidewalk, or street, back onto the

treated area of the lawn or garden will help to prevent run off to water bodies or 

drainage systems.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Environmental hazard 

statements on Dusts 

consumer outdoor 

products (e.g., for garden 

or ornamental)

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Environmental hazard “This pesticide is extremely toxic to aquatic organisms, including fish and Environmental Hazard Statement
33

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

statements on Liquid 

Ready-to-Use consumer 

outdoor products (except 

aerosols and foggers)

invertebrates. To protect the environment, do not allow pesticide to enter or run 

off into storm drains, drainage ditches, gutters or surface waters. Applying this 

product in calm weather when rain is not predicted for the next 24 hours will help 

to ensure that wind or rain does not blow or wash pesticide off the treatment area.

This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard 

Statements aerosol 

consumer (including 

foggers) outdoor products

For products that have outdoor uses:

“This pesticide is extremely toxic to aquatic organisms, including fish and 

invertebrates. Do not apply directly to or near water. Drift and run-off may be 

hazardous to fish in water adjacent to treated areas. Do not contaminate water 

when disposing of equipment, washwater, or rinsate. See Directions for Use for 

additional precautions and requirements.” 

“This pesticide is highly toxic to bees exposed to direct treatment on blooming 

crops or weeds. Do not apply this product or allow it to drift to blooming crops or 

weeds while bees are actively visiting the treatment area.” 

Environmental Hazard Statement

Precautionary statement 

for all permethrin canine 

spot on products (i.e. 

45/65% permethrin 

concentrations spot-on 

products for dogs)

Note to registrant:

All cat warning labels will be placed within a shaded box within the 

Precautionary Statements on the label. The coloring of the box and text will be 

such to provide a contrasting color to other label text. The shaded box must 

contain the following.

“DO NOT USE ON CATS. May be toxic or potentially fatal if applied to or 

ingested by cats. Accidental application to cats and/or grooming a recently 

treated dog may result in tremors and/or uncoordinated muscle movements. If 

Precautionary Statement
34

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

this occurs, immediate veterinary care should be provided.”

Each label must include at least one cat slash icon. This icon may be in the 

shaded box or in other areas on the label. 

Each individual tube must be labeled with the “DO NOT USE ON CATS” 

statement or cat slash icon. 

Include the following statement prominently on the front panel of product 

packaging (in bold), “DO NOT USE ON CATS”

Entry Restrictions 

for products that do not 

contain any directions for 

uses when people are 

permitted to be present in 

the treated area (e.g. . 

applications to pets)

Entry Restriction for products applied as a spray except for sprays applied 

directly to domestic animals: 

“Do not allow adults, children, or pets to enter the treated area until sprays have 

dried.”

Entry Restriction for products applied dry:

“Do not allow adults, children, or pets to enter the treated area until dusts have 

settled.”

Entry Restriction for products applied as a space spray or as a fog:

“Do not allow adults, children, or pets to enter until vapors, mists, and aerosols 

have dispersed, and the treated area has been thoroughly ventilated.”

Total release foggers labeled for indoor use must contain the following entry 

restriction:

Directions for use under General Precautions and 

Restrictions
35

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

“Wait two (2) hours after application, then open windows, vents and doors for 

two hours. If an odor is still detected additional ventilation is required.” 

Note to Registrant: If there is information that justified a change in the duration 

after application (2 hours), submit the information to the Agency.

Entry Restrictions for 

products products that 

only contain directions 

for uses when people are 

permitted to be present 

(e.g. pet applications)

Note to Registrants: No entry restrictions are required. See below under Use 

Restrictions for further requirements. 

Directions for use under General Precautions and 

Restrictions

Entry Restrictions for 

products that contain 

directions for uses when 

people are permitted to be 

present in the treated area 

(e.g. applications to pets) 

AND for use on other 

sites as a surface spray.

Entry restriction for products applied as a space spray ( except for sprays 

applied directly to domestic animals): 

“Except when (insert application method), do not allow adults, children, or pets to 

enter the treated area until sprays have dried.”

Products labeled for use as a surface spray (does not apply to products 

applied directly to domestic animals): 

“Except when (insert application method) do not allow adults, children, or pets to 

enter until sprays have dried.”

Note to Registrant: An example is as follows, “Except when applying to pets or 

livestock, do not enter or allow other to enter until sprays have dried.”

Directions for use under General Precautions and 

Restrictions

General Application 

Restrictions for products 

solely labeled for use 

No general application restrictions are required. See below under “Use 

Restrictions” for further requirements. 

Place in the Direction for Use. 
36

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

when people may be 

present (e.g. misting 

systems, fabric treatments 

and pet applications)

General Application 

Restrictions for all 

products that do not 

contain directions for use 

in drains or sewers

Products labeled for use around or near floor drains must contain the 

following statement. 

“Application is prohibited directly into sewers or drains, or to any area like a 

gutter where drainage to sewers, storm drains, water bodies, or aquatic habitat can 

occur. Do not allow the product to enter any drain during or after application.”

Directions for Use

General Application 

Restrictions for all 

products that contain 

directions for use in 

drains or sewers

“Do not apply directly to sewers or drains, or to any area like a gutter where 

drainage to sewers, storm drains, water bodies, or aquatic habitat can occur, 

except as directed by this label.”

Directions for Use

Additional Application 

Restrictions For Outdoor 

Residential Use

General Outdoor Surface and Space Sprays, except for outdoor fogging 

devices):

“All outdoor applications must be limited to spot or crack-and-crevice treatments 

only, except for the following permitted uses:

(1) Treatment to soil or vegetation around structures;

(2) Applications to lawns, turf, and other vegetation;

(3) Applications to building foundations, up to a maximum height of 3 feet. 

Other than applications to building foundations, all outdoor applications to 

impervious surfaces such as sidewalks, driveways, patios, porches and structural 

surfaces (such as windows, doors, and eaves) are limited to spot and crack-andcrevice applications, only.”

Note to registrant: If the end use product does not contain directions for use 

consistent with the exceptions above the exceptions may be eliminated from the 

Directions for Use under General Precautions and 

Restrictions 
37

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

label.

Requirements for Granular Formulations labeled or intended for outdoor 

residential uses: 

“Apply this product directly to the lawn or garden area. Water treated area as 

directed on this label. Do not water to the point of run-off.”

“Do not make applications during rain.”

Requirements for Liquid, Dust, and Ready to Use Formulations products 

labeled or intended for outdoor residential uses: 

“Do not water the treated area to the point of run-off.”

“Do not make applications during rain.”

Additional Application 

Restrictions For Indoor 

Residential Use

Products labeled for or intended for use as directed surface sprays for use on 

residential indoor surfaces (excludes Ready to Use products and Total 

Release Foggers: 

“Do not apply as a broadcast treatment to indoor surfaces at residential sites, 

including nurseries, day care centers, schools, hospitals, and nursing homes.” 

Formulation into products intended for use in Total Release Foggers

(residential indoor use):

Total release foggers labeled for indoor use at residential sites must be formulated 

Directions for Use under General Precautions and 

Restrictions
38

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

to contain no more than 0.58% permethrin active ingredient.

Note to Registrant: The Agency will consider products with higher 

concentrations if the registrants of the products can provide justification or data to 

the Agency which demonstrates that an equivalent ISR of 5.6 μg/cm2, or less, will 

results in a room size of 2000 ft3 or less. 

Use-Specific Application 

Restrictions for all liquid 

and wettable powder 

labels 

(Outdoor residential 

misting system 

requirement)

Note to registrant: also 

express this application 

rate as pounds or gallons 

of end-use product 

formulation.

Products not labeled or intended for use in outdoor residential misting 

systems must contain the following statement: 

“Not for use in outdoor residential misting systems.”

Products labeled or intended for use in outdoor residential misting systems 

must contain the following statements: 

“Directions for use in outdoor residential misting systems:”

“When using this product installers and service technicians must comply with the 

license, certification, or registration requirements of the state(s), tribe(s), or local 

authority(ies) where they are installed.” 

“Do not apply this pesticide when people, pets, and/or food are present.”

“Do not use in an evaporative cooling system.”

“Direct nozzles to spray towards the target area and away from swimming pools, 

water bodies, or eating and cooking areas.” 

Directions for Use under General Precautions and 

Restrictions and/or Application Instructions
39

Summary of Labeling Changes for Permethrin

Revised 8/29/2011

Description Amended Labeling Language Placement on Label

“Do not set nozzles to direct mist near outside air condition systems or other 

home air intakes.”

“If used in a system with a reservoir tank for the end use dilution, the system 

reservoir tank must be locked. Securely attach the end use pesticide label and a 

dilution statement to the system reservoir tank in a weather protected area or 

plastic sleeve. The dilution statement must be phrased as follows: this container 

holds __ parts [product name] to __ parts water”

“If used in a direct injection system, the pesticide container must be locked. 

Securely attach the end use label to the pesticide container in a weather protected 

area or plastic sleeve.” (These instructions not applicable to wettable powder 

products). 

“If the system works on an automatic timer, set the timing for application when 

people, pets, and/or food are unlikely to be present.”

“If the system works when a person operates a remote activation device, then 

application of this pesticide when people, pets, and/or food are present is 

prohibited.”

“Contact the system manufacture for guidance or assistance to ensure compliance 

with the following requirement: 

This product may only be used in systems that have been calibrated to apply no 

more than the maximum application rate of 0.25 grams per 1000 cubic feet per 

day.” 

1

PPE that is established on the basis of Acute Toxicity of the end-use product must be compared to the active ingredient PPE in this document. The more 

protective PPE must be placed in the product labeling. For guidance on which PPE is considered more protective, see PR Notice 93-7. 
40