TABLE OF CONTENTS 

TERBUTHYLAZINE : PRODUCT CHEMISTRY/ ENVIRONMENTAL 

FATE AND ECO-EFFECTS SCOPING DOCUMENT 

PAGE 

No. 

TERBUTYL AZINE............................................ 

 2 

APPENDICES--------------------------------------------------------------------------------- 

12 

2
REGISTRATION REVIEW DOCUMENT

PRODUCT CHEMISTRY, ENVIRONMENTAL FATE AND

 ECOLOGICAL EFFECTS SUMMARY FOR TERBUTYLAZINE

PCCode: 080814 Case No. 2645

Chemical name Use patterns/use sites 

AMA-204 Recirculating cooling 

towers/ornamental fountains 

Bellacide 325 Recirculating cooling towers 

Bellacide 320 Recirculating cooling towers 

Bellacide 329 Recirculating cooling towers 

Regulatory History

 As an herbicide Terbuthylazine was first registered in 1975. For its uses on or in 

corn fodder, and forage, corn grain (popcorn grain included), sorghum forage and grain, 

tolerances were established earlier; however since no herbicidal uses were registered, 

these tolerances were revoked in 1992.This document only addresses the antimicrobial 

uses of this chemical 

Antimicrobial uses of algaecide, microbiocide/ microbiostats as end-use formulations of 

Terbuthylazine were registered in 1986. At present four products containing 

Terbuthylazine are registered to a total of 2 companies. 

Table 1: Registered Active Products for TurbuthylAzine 

EPA Reg. 

Number 

Product Name Formulation 

Type 

% Active 

Ingredient

Registrant 

83451-7 Bellacide 320 MUP 96 BWA Water Additives 

US, LLC 

9386-34 AMA-204 Aqueous 

Dispersion 

4.0 Kemira Chemicals, Inc 

83451-8 Bellacide 329 Aqueous 

Dispersion

44.7 BWA Water 

Additives US, LLC 

83451-9 Bellacide 325 Aqueous 

Dispersion

4.0 BWA Water 

Additives US, LLC 

3
Table 2. Chemical Identity 

Common Name Terbuthylazine 

Chemical Name 6-chloro-N-(1,1-dimethylethyl)-N-ethyl)-1,3,5-triazine 

2,4-dimamine 

IUPAC 6-chloro-N-(1,1-dimethylethyl)-N-ethyl)-1,3,5-triazine 

2,4-dimamine 

Molecular Weight 229.71 

PC Code 80814 

CAS Registry Number 5915-41-3 

Molecular Formula C9H16ClN5

Registration Review Case No. 2645 

Registration Review Case Name Terbuthylazine 

Classification: Organic 

Structure: 

 

Science Findings:

A few data gaps for each discipline are noted below. 

Product Chemistry Summary

Table 3: Physical and Chemical Properties of Terbuthylazine

Guideline 

No. 

Physical and Chemical Properties Value 

830.1550 Product identity and composition Refer to Table 2 

830.1600 Description of materials used to 

produce the product 

CBI 

830.1620 Description of production process CBI 

830.1650 Description of formulation process CBI 

4
Guideline 

No. 

Physical and Chemical Properties Value 

830.1670 Discussion of formation of impurities CBI 

830.1700 Preliminary analysis CBI 

830.1750 Certified limits CBI 

830.1800 Enforcement analytical method No data 

830.1900 Submittal of samples CBI 

830.6302 Color Off-White 1 

830.6303 Physical State Powdery, globular solid1 

830.6304 Odor Rancid, putrid1 

830.6313 Stability to sunlight, normal and 

elevated temperature 

Not sensitive to metal and metal ions; stable at 

elevated temperature. Not sensitive to sunlight1 

830.6314 Oxidation/Reduction: Chemical 

Incompatibility 

No data 

830.6315 Flammability 

Flash Point 

No data 

830.6316 Explodability No data 

830.6317 Storage Stability Moderate temperature: < 1%/year1 

Tropical temperature:< 1%/year1 

830.6319 Miscibility No data 

830.6320 Corrosion Characteristic No data 

830.6321 Dielectric breakdown voltage No data 

830.7000 pH No data 

830.7050 UV/Visible absorption spectra No data 

830.7100 Viscosity No data 

830.7200 Melting Point 178-179o C1 

830.7220 Boiling point Not applicable

830.7300 Density/ Bulk density 22.04 lbs/ft3 1 /1.009 g/cc at 20 o C2 

830.7370 Dissociation Constants in water pKa is 1.9 ± 0.1 at 21 o C1 

830.7520 Particle size Not applicable 

830.7550 Octanol/water partition coefficient 

(KOW) (Log Kow ) 

3.21±0.39 1 

830.7840 Solubility in water 1.5 ppm in water1 

830-7840 Solubility in organic solvents in g/100 

ml 

Acetone: 4.3 g/100ml; ethanol: 1.5 g/100 ml; 

toluene: 1.04 g/100 ml; n-octanol: 1.25 g/100 ml; 

ethylene glycol: 0.236 g/100 ml 1 

830.7950 Vapor pressure 5.8 x 10-7 mm Hg at 25 o C1 

Note: 1) The data in Table 3 are reported from industry data submitted in 1990 (MRID#: 

416033-03; 2) Calculated by the present reviewer 

Product Chemistry Data Gaps: Table 3 lists the guideline tests that are missing; The 

Agency is requiring these data to be submitted. Appendix C outlines the data 

justifications for these missing data. 

Environmental Fate and Transport Data Summary:

EPA’s Reregistration Eligibility Decision (RED) on Terbuthylazine was completed in 

1992 as it was registered as an herbicide. As an antimicrobial, it is registered for uses in 

recirculating cooling tower (outdoor use), and ornamental fountains (indoor use). Both 

uses are likely to end up in wastewater streams through down-the-drain process. 

5
Antimicrobials Division has in its database a number of environmental fate studies that 

were submitted for the agricultural uses. These studies are not sufficient to conduct an 

environmental fate and transport risk assessment/risk characterization for AD uses. Table 

4 provides the environmental fate and transport profile of terbuthylazine. The fate studies 

were conducted on the MUP (96%) Bellacide 320 

 Table 4 

 Environmental Fate and Transport Data 

Guideline No. / Study Type Results/Conclusions Reference 

835.2120/ Hydrolysis: 

Abiotic 

Half life at pH 5 ~ 73 days; 

Half life at pH 7 = 205 

days; 

Half life at pH 9 = 194 days 

Conclusions:

Terbuthylazine is stable and 

persistent at all three pHs 

under abiotic conditions 

MRID#: 419077-07 

Study was accepted 

835.2240/ Photodegradation 

in water 

Abiotic 

The study was done at pH 

7, with radiolabeled (C-14) 

Bellacide 320. 

Conclusions:

Terbuthylazine did not 

degrade to any noticeable 

point and can be considered 

as stable persistent 

photochemically. This 

indicates that 

Terbuthylazine will not 

degrade on surface water 

bodies under abiotic 

conditions 

MRID#: 419948-01 

Study was accepted 

835.4300/Aerobic Aquatic 

Metabolism 

Biotic 

Under aerobic conditions, in 

a hydrosoil system, 

Terbuthylazine has a half 

life of ~ 39 days 

Conclusions: 

Terbuthylazine is stable in 

soil, but is not classified as 

persistent as the half life is 

< 60 days. 

MRID#: 427900-01 

Study was accepted 

835. 4400: Anaerobic 

Aquatic Metabolism 

Biotic 

Under anaerobic conditions, 

and in a hydrosol system 

Terbuthylazine degraded 

with a half life of about 69 

days 

MRID#: 431762-01 

Study was accepted 

6
Conclusions: 

Terbuthylazine is stable 

under anaerobic condition, 

but can be classified as 

moderately persistent under 

anaerobic conditions. 

Environmental Fate and Transport Conclusions: 

Terbuthylazine is persistent under abiotic conditions and also moderately stable under 

biotic, aerobic and anaerobic conditions in aquatic systems 

Environmental Fate and Transport Data Gaps: The Agency anticipates requiring for 

the following data sets on environmental fate and transport for terbuthylazine 

(835.3110) Ready Biodegradability 

(835.1110) Activated Sludge Isotherm 

Ecological Effects Data Summary:

Terbuthylazine was assessed for eco-effects as an agricultural pesticide and a RED 

document was issued in 1992. For its antimicrobial uses, the acute eco-effects data is not 

sufficient to assess risks to estuarine/marine fish and mollusk; also no data is available to 

assess risks to aquatic and terrestrial (semi-aquatic) plants. Chronic data is totally absent 

at the present time. The Agency, therefore, anticipates requiring additional data to 

conduct chronic risk eco-effects risk assessment. 

Table 5 summarizes the eco-toxicity data that AD has in its database. 

 Table 5 

 Eco-Toxicity Data for Terbuthylazine 

Guideline No/ Study Type Results/Conclusions MRID# 

850.1010 

Aquatic invertebrate acute 

toxicity (daphnid) 

The 48 hour LC50 = 39.4 

mg ai/L 

Conclusions: 

Test materials is slightly 

toxic to daphnia magna 

The study did not identify 

the percent purity of the 

test substance. 

129595/92180007 

Since the study did not 

identify the percent purity 

of the test substance, this 

study is classified as 

supplemental. 

850.1010 

Aquatic invertebrate acute 

toxicity (daphnids) 

48 hour LC50 = 21.2 mg 

ai/L; NOEL < 10 mg/L 

Conclusions: 

Test material is slightly 

toxic to daphnia magna; 

Purity of the test was not 

specified 

159290 

Study not accepted as the 

purity of the substance was 

not specified 

7
850.1035 

Mysid acute toxicity test 

(shrimp) 

96 hour LC50 = 0.092 mg 

ai/L 

NOEL could not be 

established due to death at 

all doses 

Purity: 99.24% 

Conclusions: 

The test material is very 

highly toxic to mysid 

shrimp 

40543701 

Study accepted 

850. 1075 

Fish acute toxicity test 

(bluegill) 

96 hour LC50 = 7.6 ppm 

Purity: 98% 

Conclusions: 

The test material is 

moderately toxic to bluegill 

fish 

129593/92180005 

Study accepted 

850.1075 

Fish acute toxicity test 

(rainbow trout) 

96 hour LC50 = 3.6 ppm 

Purity: 98% 

Conclusions: 

The test material is 

moderately toxic to rainbow 

trout 

129594/92180006 

Study accepted 

850.2100 

Avian acute oral toxicity 

test (Mallard Duck) 

LD50 > 2510 mg ai/kg bw 

No overt toxicity symptom 

was observed; a slight body 

weight change was 

observed with the highest 

dose: 2510 mg/kg 

Conclusions: 

Terbuthylazine practically 

non-toxic to mallard 

ducklings 

Purity: 99.8% 

129142/ 92180002 

Study accepted 

850.2200 

Avian acute dietary toxicity 

test (Mallard Duck)) 

LC50 > 5620 mg/kg (usually 

expressed as ppm) 

A concentration related 

reduction in body weight 

gain and feed consumption 

was observed 

Conclusions: 

Terbuthylazine is 

practically non-toxic to 

mallard ducklings 

Purity: 99.8% 

129143/ 92180004 

Study accepted 

850.2200 

Avian acute dietary toxicity 

LC50 > 5620 mg/kg (usually 

expressed as ppm) 

129144/92180003 

Study accepted 

8
test (Bobwhite Quail) 30% mortality at 178 ppm 

level; 20% mortality at 

3160 ppm and 30% 

mortality at 5620 ppm level 

Conclusions: 

Terbuthylazine is 

practically non-toxic to 

mallard duck 

Purity: 99.8% 

Hazard Conclusions: On the acute basis, the limited data available categorize technical 

grade terbuthylazine as being very highly toxic to estuarine/marine invertebrates, 

moderately toxic to freshwater fish and slightly toxic to freshwater invertebrates. Acute 

toxicity data are not available for estuarine fish and mollusks. Aquatic and terrestrial 

(semi-aquatic) plant toxicity data are not available. Terbuthylazine is practically nontoxic to birds. 

Eco-Effects Data Gaps: 

(850.1075) Estuarine/marine fish, Acute 

(850.1055 or 850.1025) Estuarine mollusk, Acute. 

(850. 4400) Aquatic plant growth (vascular), Tier II, 4 species 

(859.5400) Aquatic plant growth (algal), Tier II 

 

Down-the drain (EFAST, version 2.0): For Estimating Surface Water Concentration 

of Terbuthylazine if disposed off into the down-the-drain from AD Uses 

Input Parameters: 

Production volume: ~ 46,000 kg/year (The Agency has assumed that the production 

volume of this chemical has not changed since 1995 RED) 

Release days: 365 days 

Wastewater Removal: 7.93 % (EPI Suite, Version 4.00) 

Bioconcentration Factor (BCF): 18.54 L/Kg (EPI Suite, Version 4.0) 

 Table 6 

 Down-the-Drain Outputs 

Dilution factor Concentration (μg/L) 

(50th percentile): 

24.22 

0.0425 

(10th percentile) 1.0 1.03 

9
Note: Table 6 shows that the concentration of terbuthylazine going to the wastewater 

treatment plant to the receiving (surface) waters is 0.0425 μg/L at 50th percentile and 1.03 

μg/L at 10th percentile. These concentrations are taken as effective environmental 

concentrations in surface water and based on these estimated values, Risk Quotients for 

acute eco-effects for aquatic organisms are calculated. Data from Table 5 and six is used. 

Results are summarized in Table 7. 

Table 7 

Estimation of Risk Quotients for Acute-Eco-Effects of Aquatic Organisms 

(Guideline #)/ 

Organisms 

LC50 

(in μg/L 

units) 

Effective 

Environmental 

Concentration 

(EEC); μg/L: 

 50* 10* 

*(percentile) 

RQ = EEC/LC50 

*(percentile) 

50 * 10* 

850.1010: Aquatic 

invertebrate (daphnids) 

39.4 E3 (48 hr) 0.0425 1.03 1.07E-6 2.6E-5 

850.1010: Aquatic 

invertebrate (daphnids) 

21.2 E3 (48 hr) 0.0425 1.03 2E-6 4.8E-5 

850.1035: Mysid acute 

toxicity test (shrimp) 

0.092 (96 hours) 0.0425 1.03 0.46 11.19 

850.1075: fish acute 

toxicity(bluegill) 

7.6E3 (96 hours) 0.0425 1.03 5.5E-6 1.35E-4 

850.1075: fish acute 

toxicity (rainbow trout) 

3.6E3 (96 hours) 0.0425 1.03 1.18E-5 2.8E-4 

Table 7 clearly indicates that no adverse acute-toxic risks are anticipated for aquatic 

invertebrates. 

10
BIBLIOGRAPHY FOR: PRODUCT CHEMISTRY, ENVIRONMENTAL FATE 

AND TRANSPORT, AND ECO-EFFECTS 

• Reregistration Eligibility Decision (RED) Terbuthylazine, March, 1995. 

http://www.epa.gov/pesticides/reregistration/status.htm

* EFAST (Version 2) 

11
 APPENDIX A 

 DATA JUSTIFICATIONS 

 ENVIRONMENTAL FATE AND TRANSPORT 

 For TERBUTHYLAZINE 

Guideline Number: 835.1110 

Study Title: Activated Sludge Sorption Isotherm 

Rationale for Requiring the Data 

The results from activated sludge sorption study would allow EPA to assess the distribution of the 

antimicrobial among the solid, aqueous, and vapor phases of WWTPs. Specifically, this study identifies 

those chemicals which sorbs to sludge biomass. 

Practical Utility of the Data 

1. How will the data be used? 

The data would be used to determine the sorption potential of terbuthylazine to activated sludge 

biomass and in biological wastewater treatment systems. 

2. How could the data impact the Agency’s future decision-making? 

If terbuthylazine is not sorbed or biodegraded then, it would pass through a biological treatment system 

unaffected and it may contaminate surface and drinking waters and also may have potential adverse 

effects to nontarget organisms.

3. What is triggering the need for this data?

Studies are needed to conduct environmental fate assessment and to determine the sorption potential of 

activated sludge for the removal of specific chemical compounds in biological wastewater treatment 

systems.

Guideline Number: 835.3110 

Data Requirement: Ready Biodegradability

Rationale for Requiring the Data 

The ready biodegradability study would enable the Agency to determine the likelihood that the 

antimicrobial pesticide of biodegrading in aquatic environments under aerobic conditions.

Practical Utility of the Data 

1. How would the data be used? 

The results from the data would be used to determine the rate and extent of aerobic biodegradation 

of terbuthylazine when it is released into aquatic environments and would help establish if 

terbuthylazine is stable or not stable under real environmental conditions. 

2. How could the data affect the risk assessment? 

If the result shows low biodegradability then, terbuthylazine would occur in significant quantities in 

WWTP effluents (water and biosolids) and in environmental compartments (e.g., surface waters) 

such that potential adverse effects to nontarget organisms, found in such environmental 

compartments, may occur. 

3. What is triggering the need for this data? 

Data are needed to conduct environmental fate assessment and to determine the ready biodegradability

of terbuthylazine

12
 APPENDIX B 

 ECOLOGICAL EFFECTS DATA REQUIREMENTS 

 TERBUTHYLAZINE 

Guideline Number: 850.1055 

Data Requirement: Acute Marine Bivalve Embryo Larvae Toxicity 

Rationale for Requiring the Data 

As part of a Tier I risk assessment, three aquatic animal species are routinely tested by the agency as 

indicators of potential toxicity to aquatic life and ecosystem health. These studies allow the Agency to 

categorize terbuthylazine as toxic or non-toxic to aquatic animal life and to perform ecological risk 

assessments. If toxic, additional higher tier tests would be needed to refine the risk assessment. An 

endangered species assessment for endangered or threatened estuarine and marine aquatic fish and 

invertebrates is not possible without these studies. Research bears out that data for a fish cannot serve as a 

surrogate for an invertebrate and that shrimp react differently to toxicants than bi-valves due to their 

physiology and location in the water column. Also, data for freshwater species cannot serve as surrogate 

data for estuarine/marine species due to differences in water pH, salt content, and other variables that may 

affect the test substance. 

Practical Utility of the Data 

1. How would the data be used? 

These studies would be used to evaluate the toxicity of terbuthylazine to non-target and 

endangered/threatened aquatic animals in estuarine and marine aquatic ecosystems. 

2. How could the data affect the risk assessment? 

Adverse effects to aquatic animal species in estuarine and marine aquatic ecosystems may result in 

mitigation to protect species at risk. Mitigation might include reduced label dosages, neutralization of 

effluents prior to discharge into water, restrictions on use in sensitive ecosystems or where endangered 

species are present, or other mitigation measures. 

3. What is triggering the need for this data? 

Increased concern from state regulators and the public to evaluate impacts on endangered species and 

persistence in the environment, since initial registration, have triggered the need for these studies. Aquatic 

animals are critical to the food chain and ecosystem health and productivity. 

13
Guideline Number: 850.1075 

Data Requirement: Acute Fish Toxicity (estuarine/marine)

Rationale for Requiring the Data 

Sport fishing and commercial fishing have a high impact on the United States economy. The acute 

toxicity tests with estuarine/marine fish are designed to measure mortality during short-term (96-h) 

aquatic exposure to a range of concentrations of the pesticide in water. The preferred test species is 

Atlantic silverside (Menidia menidia) for salt water.

Practical Utility of the Data 

1. How will the data be used? 

Data would be used to determine concentration-response curves and calculate LC50's (with 95% 

confidence intervals) for 24, 48, 72, and 96 h. Additionally, a NOEC for 96 h is reported. The 

results from these studies may also provide information for a concentration-selection rationale for 

fish early-life stage study (OPPTS 850.1400) and the fish life cycle study (OPPTS 850.1500). 

2. How could the data affect the risk assessment? 

There are many estuarine/marine fish species that are listed as threatened and endangered in the 

United States. Although the Atlantic silverside is the preferred species, the sheepshead minnow is 

considered a surrogate species to represent all marine/estuarine fish species in the risk assessment 

process. As part of the acute risk assessment for aquatic animals, the lowest EC50 or LC50 for 

estuarine/marine fish is used in the RQ equation. An acute RQ > 0.5 would indicate an acute LOC, 

defined as the potential for acute risk to non-target organisms which may warrant regulatory action 

in addition to restricted use classification. An acute RQ > 0.1 would result in an acute restricted use 

LOC, defined as the potential for acute risk to non-target organisms, which may be mitigated 

through restricted use classification. An acute RQ > 0.05 would fall under the LOC for acute 

endangered species. 

3. What is triggering the need for this data? 

Data are needed in order to conduct an ecological risk assessment for the proposed use of 

terbuthylazine in cooling towers and determine the acute toxicity of terbuthylazine to 

estuarine/marine fish.

14
Guideline Number: 850.4400

Data Requirement: Aquatic plant growth using floating macrophyte Lemna gibba (Tier I) 

Rationale for Requiring the Data 

Aquatic plants are essential components of any healthy ecosystem. Plants provide food, shelter, and 

oxygen to animal species. Lemna represents floating aquatic macrophytes. As part of a Tier I risk 

assessment, one freshwater aquatic plant indicator species, (Lemna gibba or L. minor), is exposed to 

a range of concentrations of terbuthylazine in fresh water to measure phytotoxicity.

Practical Utility of the Data 

1. How would the data be used? 

This study would be used to evaluate the toxicity of terbuthylazine to non-target plants in aquatic 

ecosystems. Data from these studies would be used to plot concentration response curves for total 

frond number, growth rate (as number of fronds per day), and mortality (percentage of dead fronds to 

total number of fronds). EC05s, EC50s, and EC90s would be calculated from the curves. Tier II 

(definitive) testing is not required if Tier I testing results in an EC50 greater than 1000 mg/L or less 

than the analytical detection limit. Tier II tests may also include endpoints such as measurements of 

chlorophyll pigments, biomass, and more detailed observations of frond appearance (i.e., decrease in 

size, necrosis, chlorosis, or sinking). 

2. How could the data affect the risk assessment? 

Lemna spp. is used to represent all aquatic plants in the risk assessment process. Adverse effects to 

non-target plants in aquatic ecosystems may result in mitigation to protect species at risk. Mitigation 

might include reduced label dosages, neutralization of effluents prior to discharge into water, 

restrictions on use in sensitive ecosystems or where endangered species are present, or other 

mitigation measures. 

Aquatic plants may be affected where terbuthylazine is used as a bacteriostat or fungicide. If EPA is 

unable to evaluate the potential risks to aquatic plants associated with the bacteriostat or fungicide 

uses of terbuthylazine, these risks must be presumed. As part of the risk assessment for aquatic 

vascular plants, the lowest EC50 is used in the RQ equation. The LOC for endangered and nonendangered plants is defined as a RQ > 1. 

3. What is triggering the need for this data? 

Data are needed in order to conduct an ecological risk assessment for the uses of terbuthylazine as a 

bacteriostat and fungicide and determine its effects on aquatic plants because they are critical to 

ecosystem health and productivity.

15
Guideline Number: 850.5400 

Study Title: Algal toxicity (Tier II)

Rationale for Requiring the Data

As part of a Tier I risk assessment, one indicator plant species is tested for phytotoxicity. This study 

would allow the Agency to categorize terbuthylazine as toxic or non-toxic to plants. If toxic, 

additional higher tier plant tests would be needed. An endangered species assessment for endangered or 

threatened plants is not possible without this study.

Practical Utility of the Data

1. How will the data be used? 

This study would be used to evaluate the toxicity of terbuthylazine to non-target plants in terrestrial and 

aquatic ecosystems.

2. How could the data impact the Agency’s future decision-making? 

Adverse effects to non-target plants in terrestrial and aquatic ecosystems may result in mitigation to 

protect species at risk. Mitigation might include reduced label dosages, neutralization of effluents prior 

to discharge into water, restrictions on use in sensitive ecosystems or where endangered species are 

present, or other mitigation measures. 

3. What is triggering the need for this data?

Increased concern from state regulators and the public to evaluate impacts on WWTP operations, 

endangered species, and persistence in the environment, since initial registration, have triggered the need 

for this study. Green algae are critical to ecosystem health and productivity. 

16
17

 APPENDIX C 

 PRODUCT CHEMISTRY DATA REQUIREMENTS 

Guideline Number: 830.1800 

Study Title: Enforcement Analytical Method 

Guideline Number: 830.6314 

Study Title: Oxidation/Reduction: Chemical Incompatibility 

Guideline Number: 830.6315 

Study Title: Flammability/Flash Point 

Guideline Number: 830.6316 

Study Title: Explodability 

Guideline Number: 830.6319 

Study Title: Miscibility 

Guideline Number: 830.6320 

Study Title: Corrosion Characteristic 

Guideline Number: 830.6321 

Study Title: Dielectric Breakdown Voltage 

Guideline Number: 830. 7000 

Study Title: pH 

Guideline Number: 830.7050 

Study Title: UV/VIS absorption Spectra 

Guideline Number: 830.7100 

Study Title: Viscosity 

Rationale for Requiring the Data 

Product chemistry requirements are necessary for registration of a pesticide. These data provide the 

complete characterization of a chemical. 

Practical Utility of the Data 

1. What is the value of this study? 

These data are needed to support the registration to allow EPA to evaluate the potential of the product 

to cause unreasonable adverse effects on man and the environment. The data requirements are intended 

to generate the data and information necessary to address concerns pertaining to the identity, 

composition, potential adverse effects and the environmental fate of each product. Product chemistry 

data requirements are comprised of product identity and composition data along with the physical and 

chemical characteristics of a pesticide chemical. 

2. How will the data be used? 

This is basic information about the chemical which ensures chemical identity and is used to form the 

basis for labeling and product safety. 

3. How could the data affect the risk assessment? 

Product chemistry data help in the characterization of the pesticide and some of these 

characteristics become important parameters in various sections or risk assessment (vapor 

pressure for exposure, Kow for bioaccumulation etc.)