Exhibit 10.24



PREMIER PURCHASING PARTNERS, L.P.

AMENDMENT NUMBER #223 TO GROUP PURCHASING AGREEMENT



CONTRACT#: PP-PH-APP01



Product Category: Pharmaceuticals



(Extension
of Term)



This Amendment Number 223
(Amendment), is entered into effective December 12, 2003, (the Effective Date), and shall amend and modify the Group Purchasing Agreement (Contract #: PP-PH-APP01) by and between Premier Purchasing Partners, L.P.
(Purchasing Partners), and American Pharmaceutical Partners, Inc. (Seller), dated effective December 12, 1997 (the Agreement), as follows:



1. Extension of Term of Contract. Article 1.0 of the Agreement is hereby amended such that the term of the Agreement
shall be extended until March 31, 2004 (the Expiration Date). The Agreement shall remain in effect until the Expiration Date, unless earlier terminated pursuant to the terms of the Agreement.



2. Other terms and Conditions. All other terms and conditions of the
Agreement shall remain in full force and effect.



This
Amendment is hereby executed as of the Effective Date by the parties authorized representative set forth below.







|                                                          |  |  |  | 
|--------------------------------------------------------- |  |  |  | 
|PREMIER PURCHASING PARTNERS, L.P. (Purchasing Partners) |  |  |  | 

|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|--- |  | ---------------------------------------- |  | ---------------------------- |  | ------------------------------------------------- |  | ------------- |  | ----------------------------
|By: |  | PREMIER PLANS, LLC., Its General
Partner |  |                              |  | AMERICAN PHARMACEUTICAL PARTNERS, INC. (Seller)
|    |  |                                          |  |                              | 
|    |  | By:                                      |  | /s/    Anthony J. Gulczynski |  |                                                   |  | By:           |  | /s/    Jeff Davey           
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              | 
|    |  | Printed Name:                            |  | Anthony J. Gulczynski        |  |                                                   |  | Printed Name: |  | Jeff Davey                  
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              | 
|    |  | Title:                                   |  | Vice President, Pharmacy     |  |                                                   |  | Title:        |  | Manager, Corporate Marketing
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              | 
|    |  | By:                                      |  |                              |  |                                                   |  | By:           |  | /s/    Jeffrey Yordon       
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              | 
|    |  | Printed Name:                            |  | Robert L. Hamon              |  |                                                   |  | Printed Name: |  | Jeffrey Yordon              
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  | Senior Vice President, Group |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              | 
|    |  | Title:                                   |  | Purchasing Services          |  |                                                   |  | Title:        |  | C.O.O.                      
|    |  |                                          |  |                              |  |                                                   |  |               |  |                             
|    |  |                                          |  |                              |  |                                                   |  |               |  |