Exhibit 10.13


 


LICENSE AGREEMENT

AMENDMENT #4


 


WHEREAS,
effective as of December 1, 2014, and as further amended September 20, 2016, September 12, 2017, and February 21, 2017, Miromatrix
Medical Inc., a corporation organized under the laws of the State of Delaware and having an office 10399 West 70th Street, Eden Prairie,
MN 55344 ("Miromatrix") and Mayo Foundation for Medical Education and Research, a not for profit corporation with an address
at 200 First Street SW, Rochester, MN 55905 ("Mayo") executed a License Agreement (the "Agreement") for Services as
outlined in the Agreement.


 


WHEREAS, Miromatrix and Mayo wish to amend said Agreement.


 


NOW, THEREFORE, Miromatrix and Mayo agree as follows:


 


		1.	The Term of the Agreement shall be extended for an additional 6 month period. Accordingly,
the new expiration date of the Agreement shall be June 30, 2019.



		2.	Miromatrix has agreed to provide additional funding of $444,448 for year three
of the Project. Accordingly, the attached Exhibit B-2 shall amend Section 3 of the Agreement.



		3.	The parties wish to add an additional project to the Statement of Work. Accordingly,
the attached Exhibit A-1 shall hereby amend the Statement of Work/the Project.



		4.	Except as specifically provided herein, the terms and conditions of the Agreement
shall remain in force.



 


IN WITNESS WHEREOF, the
Parties have executed this Amendment which shall be effective as of the last dated signature below.


 


	MIROMATRIX MEDICAL INC.  	 	MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH    
   
	 	 	 
	By:	/s/ Jeff Ross	 	By:	/s/ Virginia M. Bruce
	Name:	Jeff Ross	 	Name:	Virginia M. Bruce
	Title:	CEO	 	Title:	Director, Legal Contract Adminis-tration
	Date:	1/23/2018	 	Date:	1/24/2018






 






     


     


    

 





Budget - Exhibit
B-2


 


	U MAYO CLINIC  

                                                          

                                                         PI
Name:          Scott Nyberg, MD, PhD  

                                                          

                                                         MCR Funding Proposal Number: FP86573-A1-A1-A1-A1  

                                                          

                                                         Sponsor: Miromatrix Medical Inc.

Date: 12/27/07              

	Study Title: Amendment #4: Miromatrix/Mayo Transplantable Liver Project (Nyberg)



 


	 	 	1/1/18-12/31/18**	 
	Personnel: (Includes salary and benefits*):	 	$	77,683	 
	Dr. Scott Nyberg, PI	 	 	 	 
	Bruce Amiot, Business Analyst	 	 	 	 
	 	 	 	 	 
	Lab Supplies:	 	 	 	 
	Media	 	$	108,000	 
	ICP Probes	 	$	29,000	 
	 	 	 	 	 
	Internal Services:	 	 	 	 
	Cr scans	 	$	7,200	 
	Pigs + OR	 	$	72,000	 
	Pig Harvests	 	$	24,000	 
	Auto Transplants	 	$	24,000	 
	 	 	 	 	 
	Sub-Total	 	$	341,883	 
	lndirects (30%)	 	$	102,565	 
	 	 	 	 	 
	BUDGET TOTAL	 	$	444,448	 




 


Payment Terms: The total budget above will be payable in four quarterly payments of $111,112 each. The first payment of $111,112 will be payable upon execution of the contract amendment. The remaining three payments will be invoiced at 3 months, 6 months, and 12 months after contract amendment execution.


 


*Salary and benefit rate information is confidential. Mayo cannot share individual costs or rate information, as this would be against Mayo policy


 


** This budget only reflects the additional funds that are being added with amendment #4.


 






     


     


    

 


Exhibit A-1


 


Project 1: Implantation of a revascularized decellularized
liver graft with autologous portal hepatocyte seeding post transplantation.


 


Project 2: The model development and testing of a recellularized
liver grafts to provide functional support in a pig model for 48 hours.