Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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the parent compound only. For water, the highest estimate from conservative models was used 

for both the acute and the chronic dietary exposure analyses.

Based on these highly conservative assumptions, acute dietary (food and water) risk estimates at 

the 95th percentile of exposure are less than or equal to 9.4% of the acute population-adjusted 

dose (aPAD) for all population subgroups. Chronic dietary (food and water) risk estimates are 

less than or equal to 44% of the chronic population-adjusted dose (cPAD) for all population 

subgroups. Generally, HED is concerned when risk estimates exceed 100% of the PAD; 

therefore, all acute and chronic dietary risk estimates are below HED’s level of concern (LOC).

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. For acute 

and chronic assessments, the risk is expressed as a percentage of a maximum acceptable dose 

(i.e., the dose that HED has concluded will result in no unreasonable adverse health effects). 

This dose is referred to as the population adjusted dose (PAD). The PAD is equivalent to the 

point of departure (POD, NOAEL, LOAEL, e.g.) divided by the required uncertainty or safety 

factors.

For acute and non-cancer chronic exposures, HED is concerned when estimated dietary risk 

exceeds 100% of the PAD. References that discuss the acute and chronic risk assessments in 

more detail are available on the EPA/pesticides web site: “Available Information on Assessing 

Exposure from Pesticides, A User’s Guide,” 21-JUN-2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 (20-AUG1999).

The most recent dietary risk assessment for thiamethoxam was conducted by Dennis McNeilly

(D392489, 29 Sept 2011).

II. Residue Information

Tolerances have been established for both thiamethoxam (40CFR §180.565) and clothianidin 

(40CFR §180.586) on a variety of commodities. These analyses were performed to support the 

Section 3 request for an increased tolerance for thiamethoxam residues in/on imported coffee. 

Thiamethoxam is used to treat various agricultural crops, turf grass, sod farms, golf courses, 

residential lawns, indoor residential area (crack and crevice treatment), ornamental plants grown 

in greenhouses, and Christmas tree farms. Tolerances are established for residues of 

thiamethoxam and its metabolites and degradates in or on numerous food and feed commodities. 

Tolerances range from 0.02 ppm in several commodities to 4.5 ppm in head and stem Brassica

(subgroup 5A). The residue of concern for this dietary risk assessment is thiamethoxan and its 

metabolite, clothianidin.
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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As discussed above, thiamethoxam’s major metabolite is CGA-322704, which is also the 

registered active ingredient clothianidin. Clothianidin has a complete toxicological database and 

appears to have effects in mammals that are different from those of thiamethoxam. Prior to 

receipt of the complete toxicity database for clothianidin, the Agency assumed, based on 

structural similarity, that the toxicity profile for clothianidin was equivalent to that of 

thiamethoxam, and conducted risk assessments on the combined thiamethoxam and clothianidin 

residues. The complete database has demonstrated that clothianidin does not have the same 

toxicity profile, and residues of clothianidin need not be added to residues of thiamethoxam and 

compared to the thiamethoxam endpoints for risk assessment. Instead separate dietary exposure 

and risk assessments should be conducted for thiamethoxam and clothianidin. However, given 

the complexity of previous assessments with combined residues, the Agency is continuing to 

include residues of clothianidin from thiamethoxam uses in the thiamethoxam risk assessment 

recognizing that this is an overestimate of risk. 

Table 1. HED-Recommended Food Tolerance for Thiamethoxam’s Use in/on Imported 

Coffee Beans.

Commodity Proposed 

Tolerance (ppm)

Recommended 

Tolerance (ppm)

Comments; Correct 

Commodity Definition

Tolerances Proposed under 180.565(a)

Coffee 0.20 0.20 Coffee, bean, green

1

Note: The current tolerance for 

coffee, bean, green is 0.05 ppm.

1 – There are no US registrations as of Nov 15, 2012.

Acute Assessment

The acute assessment is based on tolerance level residues of thiamethoxam/clothianidin (the 

tolerance is for combined residues). The drinking water estimate for the acute analysis provided 

in Table 2 (and explained in Table 3) includes residues of thiamethoxam from thiamethoxam 

uses, and is discussed in Section IV below. A complete listing of the residues and processing 

factors used in the acute analysis is included in Attachment 1.

Chronic Assessment

All of the inputs, except for the increased tolerance for coffee, are derived from HED’s Sept 29, 

2011 review for thiamethoxam (D392489, Dennis McNeilly). The HED-recommended tolerance 

level for coffee is used (0.20 ppm). The drinking water estimate for the chronic analysis 

provided in Table 2 (and explained in Table 3) includes residues of thiamethoxam from 

thiamethoxam uses, and is discussed in Section IV below. Tolerance level (4.0 ppm) was used 

for leaf lettuce for both the acute and chronic analyses. A complete listing of the residues and 

processing factors used in the chronic analysis is in Attachment 3.
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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The chronic assessment makes use of tolerance level residues, average residue values or the 

highest observed residue value from the thiamethoxam field trials. Anticipated residues were 

evaluated for selected commodities only, which were listed in HED’s dietary analyses for 

thiamethoxam (D392489, D. McNeilly, 29 Sept 2011). Although monitoring data are available 

for some commodities, field trial residues were used for all the uses, along with a high-end 

estimate of residues in drinking water. Therefore this assessment is considered to be highly 

conservative.

For the purpose of determining an FHE anticipated residue, the FHE tolerance of 0.02 was 

divided by a factor of 2 (ChemSAC Database, Policy Issues Addressed (Updated 2/27/98), 

2_POLICY.TBL.doc). As a result, a residue value of 0.01 ppm was used for all commodities for 

which tolerances have not been established.

Processing factors

Empirical processing factors were used when available. For food forms without empirical 

processing factors, DEEM 7.81 default values were used. A complete listing of the empirical 

processing factors used can be found in Table 2 below. Note: Processing factors are not used 

for residues reflecting the use in food handling establishments. Use of processing factors would 

not be appropriate for this case since the processed commodities would likely be treated after 

processing.

Livestock 

HED continues to conclude that residues in eggs and poultry meat, fat, and meat byproducts 

remain a 40CFR §180.6[a][3] situation (there is no expectation of finite residues in these 

commodities). As a result, tolerances are still not required in any poultry commodities.

The dietary burden for cattle and/or swine have not increased significantly from those previously 

calculated. Therefore, the current tolerances in livestock commodities are still appropriate, and 

the residue estimates for livestock commodities are as recommended in the previous 

thiamethoxam risk assessment (D392489, D. McNeilly, 29 Sept 2011).
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TABLE 2. INPUT TABLE FOR SELECTED THIAMETHOXAM COMMODITIES.

RAC Blending 

Classification

Data

Source

No. of

Samples

No. of

Detectable

Residues

LOD or 

LOQ

(Avg. in 

PPM)

Reference Processing

Factors (PF)1

Anticipated Residue Estimates/Tolerance

Chronic (Tol., AR)2

Artichoke, globe NB/PB FT 6 6 0.02

D281702/

D325447

N/A 0.19

Barley, grain B FT 16 10 0.02

D281702/

D325447

(PF Ref -

D281702)

0.3 pearled

0.3 bran

0.1 flour

0.086

Brassica, head and stem, 

subgroup 5-A

NB/PB FT 

(cabbage) 12 10 0.02

D281702/

D325447

N/A 0.98

Brassica, leafy greens, 

subgroup 5-B

NB/PB

FT

(mustard 

greens)

10 10 0.02

D281702/

D325447

N/A 0.82

Caneberry subgroup

13-A

PB FT 12 12 0.02

D281702/

D325447

N/A 0.12

Cereal Grains, Group 15

(except barley and rice)

B Tol. NA NA NA D391723 NA 0.02

Coffee B Tol. NA NA NA D402441 NA 0.20

Citrus, fruits:

 Orange

 Grapefruit

 Lemon

NB/PB FT

28

16

12

27

16

12

0.02 D349272

0.6 oil

0.6 juice

0.10

0.07

0.09

Food Handling 

Establishments NA FT

42

42

183

8

0.02 D376367 NA 0.01
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TABLE 2. INPUT TABLE FOR SELECTED THIAMETHOXAM COMMODITIES.

RAC Blending 

Classification

Data

Source

No. of

Samples

No. of

Detectable

Residues

LOD or 

LOQ

(Avg. in 

PPM)

Reference Processing

Factors (PF)1

Anticipated Residue Estimates/Tolerance

Chronic (Tol., AR)2

Fruit, pome, group 11 NB/PB

FT (apple)

FT (pear)

26

12

26

10

0.02

D281702/

D325447

& D265079

0.75 juice

0.06

0.06

Fruit, stone, group 12

 Cherry

 Peach 

(apricots/nectarines)

 Plum

PB

NB/PB

NB/PB

FT

FT

FT

20

20

20

20

19

8

0.02 W. Cutchin, 

12/10/03 DERs

1 prunes

0.21

0.07

0.071

Grape PB FT 24 22 0.02

D281702/

D325447

1.1 juice 0.06

Grape, raisin PB FT (grape) 24 22 0.02

D281702/

D325447

PF – D281702

2.3 0.06

Leaf Lettuce

/Crop Group 4

NB Tol. NA NA 0.02

D281702/

D343521

NA 4.0 

Peanut B FT 54 10 0.02 D376367 0.31 oil 0.05

Rice B FT 32 1 0.02

D357449/

D357450

PF – D357449

0.9 polished 

rice and rice 

bran

0.01

Soybeans B FT 30 0 0.02

D281702/

D325447

N/A 0.01
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TABLE 2. INPUT TABLE FOR SELECTED THIAMETHOXAM COMMODITIES.

RAC Blending 

Classification

Data

Source

No. of

Samples

No. of

Detectable

Residues

LOD or 

LOQ

(Avg. in 

PPM)

Reference Processing

Factors (PF)1

Anticipated Residue Estimates/Tolerance

Chronic (Tol., AR)2

Spearmint oil B N/A N/A N/A N/A

D281702/

D325447

0.05X 

(translated 

from the mint 

study) 

Tree Nuts, group 14 PB FT 12 0 0.02 D349272 N/A 0.01

Tropical Fruits NB FT 

(avocado) 10 2 0.02

D357449/

D357450

N/A 0.11

Vegetable, fruiting,’

 group 8

Tomato

Pepper

NB/PB FT

40

42

-

42

0.02

0.02

D281702/

D325447 +

D265079

PF – D265079

Tomato puree 

1.7

Tomato paste 

3.8

0.08

0.08

Vegetable, legume, group 

6

B/PB

FT

Snap beans

Lima beans

16

10

0

0

0.02

S. Tadayon,

26 Nov 2002

N/A 0.01

0.01

Vegetable, root, subgroup 

1C

NB/PB Tolerance N/A

D357449/

D357450

Potato chips 

1.2

Potato flakes 

1.7

0.05

Water (direct, indirect) N/A EFED N/A N/A N/A N/A N/A Acute= 0.13177 ppm Chronic= 0.01131 ppm

1 - The processing factors for existing uses are taken from HED’s 29 Sept 2011 memo, the sources for these processing factors are cited in the

 reference column. An average processing of 0.31 for peanut oil is the only new processing factor associated with the proposed new uses.

2 - Anticipated residues were calculated using 1⁄2 LOQ for all values below the LOQ.

3- Separate analyses were conducted and reported for thiamethoxam and clothianidin. Each compound has an LOQ of 0.01 ppm, with a combined LOQ of 0.02 ppm
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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The USDA Pesticide Data Program (PDP) monitored pesticide residues in catfish in 2008, 2009, 

and 2010. Over this 3-year period, PDP analyzed 1479 samples of catfish for thiamethoxam 

residues. None of the samples contained detectable residues. As a result, residues in fish were 

not included in the assessment.

III. Percent Crop Treated Information

Percent crop treated information was not used in either the acute or chronic analysis. 

IV. Drinking Water Data

The drinking water residues used in these dietary risk assessments were provided by EFED 

(D391528, C. Koper, 28 July 2011; and D373378, C. Koper, 20 May 2010), and incorporated 

directly into the dietary assessments. Water residues were incorporated in DEEM-FCID via 

entry into the food categories “water, direct, all sources” and “water, indirect, all sources.” 

Clothianidin, a major metabolite of thiamethoxam in plants and livestock, is not a significant 

degradate of thiamethoxam in surface or groundwater sources of drinking water. 

For surface water, the EDWCs for the crops evaluated/modeled in this assessment did not exceed 

the EDWCs for rice reported in the previous drinking water assessment (D363202, F. Khan, 07 

April 2009). The reported acute concentration of 131.77 μg/L, annual mean (chronic) 

concentration of 11.31 μg/L, and the highest 30 year annual average concentration of 11.31 μg/L 

from the rice model are higher than the reported EDWCs for various uses in Table 3. Therefore, 

the current EDWCs for surface water do not supersede the drinking water concentrations 

previously estimated for this chemical (D363202).

For groundwater, based on the proposed highest annual use rate for dry bulb onions (0.3 lbs 

ai/acre), the SCI-GROW model concentration of thiamethoxam is 4.66 μg/L. This value is the 

recommended EDWC for groundwater.

Typically, HED uses the higher of the surface or groundwater estimates for each duration when 

assessing dietary risk. For thiamethoxam, the results from the rice model are the highest 

estimates for each duration and were used in the dietary assessments. 

The models and their descriptions are available at the EPA internet website via the web link, 

http://www.epa.gov/oppefed1/models/water/. 

Table 3. Tier II Estimated Drinking Water Concentrations (EDWCs) resulting from 

applications of Thiamethoxam.

Drinking Water 

Source (model)

Use

Scenario

(modeled rate)

1-in-10 year 

acute (μg/L)

1-in-10 year 

chronic (μg/L)

30- year

average (μg/L)

Tail water 

(Rice Model)

Rice

(0.173 lbs ai/A/year)

131.771,2 11.311,3 11.311,3

Cranberry

(0.188 lbs ai/A/year)

54.7524.5034.503
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Table 3. Tier II Estimated Drinking Water Concentrations (EDWCs) resulting from 

applications of Thiamethoxam.

Drinking Water 

Source (model)

Use

Scenario

(modeled rate)

1-in-10 year 

acute (μg/L)

1-in-10 year 

chronic (μg/L)

30- year

average (μg/L)

Groundwater 

(SCI-GROW)

Dry bulb onions:

(1 app. X 0.30 lbs. 

ai/acre)

4.66 4.66 4.66

Bold text denotes maximum estimated EDWC values. All values adjusted with PCA factor of 

0.87.

1. Recommended EDWCs for surface water. 2. EDWCs based on day 1. 3. EWDCs based on average of 365 days.

Water Monitoring Data

Only very limited monitoring data are available for thiamethoxam and these data are discussed 

below; due to this limitation HED used modeling data for the drinking water residue estimate for 

both the acute and chronic dietary risk assessments.

Two small-scale prospective groundwater (PGW) monitoring studies were initiated in southwest 

Michigan in June 2001 and southwestern Georgia in the spring of 2002, to determine the 

potential for the active ingredient thiamethoxam and its degradates to reach groundwater when 

used in a vulnerable hydrogeologic setting. Analytical data were collected for 47 months (from

treatment in the spring of 2001 until May 2005) in the Michigan study and for 36 months (from 

treatment in the spring of 2002 until May 2005) in the Georgia study.

In Michigan, thiamethoxam residues found in soil-pore water samples have clearly peaked and 

then declined. No quantifiable residues of thiamethoxam > LOQ (0.05 ppb) were observed in any 

of the 3, 6, and 9-ft lysimeters after the 36, 16, and 41-MAT sampling events, respectively. By 

the 47-MAT sampling event, only trace level detections of thiamethoxam were observed in three 

of the 15-ft. lysimeter units (maximum concentration 0.11 ppb).

In Georgia, thiamethoxam residues have only been confirmed in four shallow monitoring wells 

(MW-1S, MW-3S, MW-5S, and MW-8S) during 47 months of sampling. Thiamethoxam 

residues in groundwater peaked at 43-MAT, and by 47-MAT residues were confined to two 

shallow monitoring wells only (maximum concentration 0.12 ppb). No detections of 

thiamethoxam at or greater than the analytical method LOQ have been observed in any 

groundwater samples collected from the deep monitoring wells during 47 months of sampling.

V. DEEM-FCID Program and Consumption Information

Thiamethoxam acute and chronic dietary exposure assessments were conducted using the 

Dietary Exposure Evaluation Model software with the Food Commodity Intake Database 

DEEM-FCID, Version 3.16, which incorporates consumption data from USDA’s 

NHANES/WWEIA. This dietary survey was conducted from 2003 to 2008. The data are based 

on the reported consumption of more than 20,000 individuals over two non-consecutive survey 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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days. Foods “as consumed” (e.g., apple pie) are linked to EPA-defined food commodities (e.g.,

apples, peeled fruit - cooked; fresh or N/S; baked; or wheat flour - cooked; fresh or N/S, baked) 

using publicly available recipe translation files developed jointly by USDA/ARS and EPA. For 

chronic exposure assessment, consumption data are averaged for the entire U.S. population and 

within population subgroups. However, for acute exposure assessment, consumption data are 

retained as individual consumption events. Based on analysis of the 2003-2008 WWEIA 

consumption data, which took into account dietary patterns and survey respondents, HED 

concluded that it is most appropriate to report risk for the following population subgroups: the 

general U.S. population, all infants (<1 year old), children 1-2, children 3-5, children 6-12, youth 

13-19, adults 20-49, females 13-49, and adults 50-99 years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food or foodform (e.g., orange or orange juice) on the food commodity residue list is multiplied by the 

average daily consumption estimate for that food/food form to produce a residue intake estimate. 

The resulting residue intake estimate for each food/food form is summed with the residue intake 

estimates for all other food/food forms on the commodity residue list to arrive at the total 

average estimated exposure. Exposure is expressed in mg/kg body weight/day and as a percent 

of the cPAD. This procedure is performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on an 

individual-by-individual basis. The reported consumption amounts of each food item can be 

multiplied by a residue point estimate and summed to obtain a total daily pesticide exposure for a 

deterministic exposure assessment, or “matched” in multiple random pairings with residue values 

and then summed in a probabilistic assessment. The resulting distribution of exposures is 

expressed as a percentage of the aPAD on both a user (i.e., only those who reported eating 

relevant commodities/food forms) and a per-capita (i.e., those who reported eating the relevant 

commodities as well as those who did not) basis. In accordance with HED policy, per capita 

exposure and risk are reported for analyses performed at all levels of refinement. However, for 

deterministic assessments, any significant differences in user vs. per capita exposure and risk are 

specifically identified and noted in the risk assessment.

VI. Toxicological Information

The toxicology database for thiamethoxam is complete. The scientific quality is relatively high 

and the toxicity profile of thiamethoxam can be characterized for most effects, including 

potential carcinogenic, mutagenic, developmental, and neurotoxic effects.

The Agency has determined that the 10X FQPA safety factor for the protection of infants and 

children can be reduced to 1X. There is no quantitative or qualitative evidence of increased 

susceptibility of rat or rabbit fetuses to in utero exposure to thiamethoxam in the developmental 

toxicity studies. The developmental NOAELs are either higher than or equal to the maternal 

NOAELs. The Developmental Neurotoxity (DNT) Workgroup concluded there was no evidence 

of increased quantitative susceptibility in the DNT study in rats, based on evaluation of 

additional brain morphometric data for the low- and mid-dose pups (January 17, 2007 meeting). 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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Although there is evidence of increased quantitative susceptibility for male pups of both two 

generation reproductive studies, NOAELs and LOAELs were established in these studies, and 

the Agency selected the NOAEL for testicular effects in F1 pups as the basis for risk assessment. 

The Agency is confident that the NOAEL selected for risk assessment is protective of the most 

sensitive effect (testicular effects) for the most sensitive subgroup (pups) observed in the 

toxicological database. 

In addition, the NOAELs selected for risk assessment are protective of all toxicological effects 

observed in the database including treatment-related changes in the adrenal gland, thyroid, testes 

and ovaries. Thus, the Agency believes the FQPA safety factor can be reduced to 1X and still be 

conservatively protective of human health risk.

Table 4. Toxicological Doses and Endpoints for Thiamethoxam for Use in Human Health 

Risk Assessments.

Exposure/

Scenario

Point of 

Departure

Uncertainty/ 

FQPA Safety 

Factors

Level of 

Concern for 

Risk 

Assessment

Study and Toxicological 

Effects

Acute Dietary

All populations

including 

infants and 

children 

NOAEL = 

34.5 

mg/kg/day

UFA= 10x

UFH= 10x

SFFQPA=1

aRfD=0.35 

mg/kg/day

aPAD=0.35 

mg/kg/day

Rat Developmental Neurotoxicity 

study 

LOAEL = 298.7 mg/kg/day based 

on delayed sexual maturation in 

male pups, and reduced brain

morphometric measurements.

Chronic Dietary

All populations

including 

infants and 

children

NOAEL= 1.2 

mg/kg/day 

UFA= 10x

UFH= 10x

SFFQPA=1

cRfD=0.012 

mg/kg/day

cPAD=0.012 

mg/kg/day

2-Generation reproduction study 

in Rats

LOAEL = 1.8 mg/kg/day based on

increased incidence and severity of 

tubular atrophy in testes of F1 

generation males.

2-Generation reproduction study 

in Rats (46402904) 

LOAEL = 3 (males), not determined 

(females) mg/kg/day based on 

sperm abnormalities in F1 males.

Cancer (oral, 

dermal, 

inhalation)

“Not Likely to be Carcinogenic to Humans” based on convincing evidence that a nongenotoxic mode of action for liver tumors was established in the mouse and that the carcinogenic 

effects are a result of a mode of action dependent on sufficient amounts of a hepatotoxic 

metabolite produced persistently. Quantification of cancer risk is not required. 

VII. Results/Discussion 

The DEEM-FCIDTM analyses estimate the dietary exposure of the US population and various 

population subgroups. The results of the assessments are shown in Table 5, below.
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Table 5. Summary of Estimated Dietary (Food + Drinking Water) Exposures and Risk for 

Thiamethoxam.

Population 

Subgroup

aPAD, 

mg/kg/day

Acute Estimates (95th

Percentile)1

cPAD, 

mg/kg/day

Chronic Estimates

Exposure, 

mg/kg/day

Risk,

% aPAD

Exposure, 

mg/kg/day

Risk, 

% cPAD

U.S. Population 0.35 0.017192 4.9 0.012 0.002663 22

All infants (< 1 year)20.35 0.027915 8.0 0.012 0.002560 21

Children 1-2 yrs 0.35 0.032993 9.4 0.012 0.005286 44

Children 3-5 yrs 0.35 0.027008 7.7 0.012 0.004446 37

Children 6-12 yrs 0.35 0.017406 5.0 0.012 0.002767 23

Youth 13-19 yrs 0.35 0.012830 3.7 0.012 0.002026 17

Adults 20-49 yrs 0.35 0.016102 4.6 0.012 0.002502 21

Adults 50-99 yrs 0.35 0.015572 4.5 0.012 0.002585 22

Females 13-49 yrs 0.35 0.016655 4.8 0.012 0.002585 22

1 - Results for the 99th and 99.9th percentile are reported in Attachment 2. 

2 - The population subgroup with the highest estimated exposure/risk is bolded.

The results reported in Table 5 are for the general U.S. population, all infants (<1 year old), 

children 1-2, children 3-5, children 6-12, youth 13-19, females 13-49, adults 20-49, and adults 

50-99 years. The acute results summarized in Table 5 are for the 95th percentile of exposure. A 

complete listing of acute exposure and risk estimates can be found in Attachments 1 and 2, 

respectively. A complete listing of chronic exposure and risk estimates can be found in 

Attachments 3 and 4, respectively.

As previously stated, for acute and chronic assessments, HED is concerned when dietary risk 

exceeds 100% of the PAD. The analyses indicate that the requested uses of thiamethoxam, 

coupled with currently registered uses, will result in acute and chronic dietary (food + drinking 

water) exposures that are below HED’s level of concern for all population subgroups, including 

those of infants and children.

The acute assessment indicates that Children 1-2 yrs are the most highly-exposed subgroup, 

utilizing 9.4% of the aPAD, while the general US population utilizes 4.9% of the aPAD; all risk 

estimates are below HED’s level of concern (Table 5). Similarly, risk estimates for the chronic 

dietary exposure analysis are below HED’s level of concern, with Children 1-2 years being the 

most highly-exposed subgroup, utilizing 44% of the chronic population-adjusted dose (cPAD), 

while the general U.S. population utilizes 22% of the cPAD.

VIII. Characterization of Inputs/Outputs

This assessment is based on tolerance level or anticipated residues derived from field trial 

residue data and assumes 100% CT. The exposure values represent high-end estimates and 

should be considered to be highly conservative, health-protective estimates of dietary exposure 

and risk. The Tier I Rice Model used to generate the EDWCs is expected to produce

conservative estimates of pesticides in water bodies well downstream of rice paddies. The 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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modeled estimates may exceed actual pesticide concentrations by less than one order of 

magnitude to multiple orders of magnitude.

Various other refinements could be made to the assessments. However, as there are no risk 

estimates of concern (including aggregate risk concerns), no additional refinements were 

incorporated.

IX. Conclusions

Based on highly conservative assumptions, there are no dietary (food + drinking water) risk 

estimates of concern for thiamethoxam.

HED is confident that the assessment does not underestimate risk to the general U.S. population 

or any population subgroup.

X. List of Attachments

Attachment 1. Input file for the acute dietary exposure analyses of thiamethoxam.

Attachment 2. Summary of the acute dietary exposure analysis for thiamethoxam.

Attachment 3. Input file for the chronic dietary exposure analyses of thiamethoxam.

Attachment 4. Summary of the chronic dietary exposure analysis for thiamethoxam.
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

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Attachment 1. Input File for the Acute Dietary Exposure Estimates.

Filename: C:\Documents and Settings\dmcneill\My Documents\Thiamethoxam5\060109 2010 ACUTE 

T+WATER.R08

Chemical: thiamethoxam

RfD(Chronic): .012 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): .35 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 09-26-2012/09:32:49 Program ver. 3.16, 03-08-d

Comment: Acute and Chronic RfDs = aPAD and cPAD

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

0101050000 1AB Beet, garden, roots 0.050000 1.000 1.000 

 Full comment: D357449, recommended tol.

0101050001 1AB Beet, garden, roots-babyfood 0.050000 1.000 1.000 

0101052000 1A Beet, sugar 0.050000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.050000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 0.050000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 0.050000 1.000 1.000 

0101067000 1AB Burdock 0.050000 1.000 1.000 

0101078000 1AB Carrot 0.050000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.050000 1.000 1.000 

0101079000 1AB Carrot, juice 0.050000 1.000 1.000 

0101084000 1AB Celeriac 0.050000 1.000 1.000 

0101100000 1AB Chicory, roots 0.050000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.050000 1.000 1.000 

0101190000 1AB Horseradish 0.050000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.050000 1.000 1.000 

0101251000 1AB Parsnip 0.050000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.050000 1.000 1.000 

0101314000 1AB Radish, roots 0.050000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.050000 1.000 1.000 

0101327000 1AB Rutabaga 0.050000 1.000 1.000 

0101331000 1AB Salsify, roots 0.050000 1.000 1.000 

0101388000 1AB Turnip, roots 0.050000 1.000 1.000 

0103296000 1C Potato, chips 0.250000 1.200 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.250000 1.700 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.250000 1.700 1.000 

0103298000 1C Potato, flour 0.250000 1.700 1.000 

0103298001 1C Potato, flour-babyfood 0.250000 1.700 1.000 

0103299000 1C Potato, tuber, w/peel 0.250000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.250000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.250000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.250000 1.000 1.000 

0103366000 1CD Sweet potato 0.020000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.020000 1.000 1.000 

0103371000 1CD Tanier, corm 0.020000 1.000 1.000 

0103387000 1CD Turmeric 0.020000 1.000 1.000 

0103406000 1CD Yam, true 0.020000 1.000 1.000 

0103407000 1CD Yam bean 0.020000 1.000 1.000 

0200315000 2 Radish, tops 0.800000 1.000 1.000 

0200317000 2 Radish, Oriental, tops 0.800000 1.000 1.000 

0301237000 3A Onion, bulb 0.030000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.030000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.030000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.030000 9.000 1.000 

0401005000 4A Amaranth, leafy 4.000000 1.000 1.000 

0401018000 4A Arugula 4.000000 1.000 1.000 

0401104000 4A Chrysanthemum, garland 4.000000 1.000 1.000 

0401133000 4A Cress, garden 4.000000 1.000 1.000 

0401134000 4A Cress, upland 4.000000 1.000 1.000 

0401138000 4A Dandelion, leaves 4.000000 1.000 1.000 

0401150000 4A Endive 4.000000 1.000 1.000 

0401204000 4A Lettuce, head 4.000000 1.000 1.000 

0401205000 4A Lettuce, leaf 4.000000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 16 of 32

0401248000 4A Parsley, leaves 4.000000 1.000 1.000 

0401313000 4A Radicchio 4.000000 1.000 1.000 

0401355000 4A Spinach 4.000000 1.000 1.000 

0401355001 4A Spinach-babyfood 4.000000 1.000 1.000 

0402076000 4B Cardoon 4.000000 1.000 1.000 

0402085000 4B Celery 4.000000 1.000 1.000 

0402085001 4B Celery-babyfood 4.000000 1.000 1.000 

0402086000 4B Celery, juice 4.000000 1.000 1.000 

0402087000 4B Celtuce 4.000000 1.000 1.000 

0402152000 4B Fennel, Florence 4.000000 1.000 1.000 

0402322000 4B Rhubarb 4.000000 1.000 1.000 

0402367000 4B Swiss chard 4.000000 1.000 1.000 

0501061000 5A Broccoli 4.500000 1.000 1.000 

0501061001 5A Broccoli-babyfood 4.500000 1.000 1.000 

0501062000 5A Broccoli, Chinese 4.500000 1.000 1.000 

0501064000 5A Brussels sprouts 4.500000 1.000 1.000 

0501069000 5A Cabbage 4.500000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 4.500000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 4.500000 1.000 1.000 

0501083000 5A Cauliflower 4.500000 1.000 1.000 

0501196000 5A Kohlrabi 4.500000 1.000 1.000 

0502063000 5B Broccoli raab 3.000000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 3.000000 1.000 1.000 

0502117000 5B Collards 3.000000 1.000 1.000 

0502194000 5B Kale 3.000000 1.000 1.000 

0502229000 5B Mustard greens 3.000000 1.000 1.000 

0502318000 5B Rape greens 3.000000 1.000 1.000 

0502389000 5B Turnip, greens 3.000000 1.000 1.000 

0600347000 6 Soybean, seed 0.020000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.020000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.020000 1.000 1.000 

0600350000 6 Soybean, oil 0.020000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.020000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.020000 1.000 1.000 

0601043001 6A Bean, snap, succulent-babyfood 0.020000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.020000 1.000 1.000 

0602031000 6B Bean, broad, succulent 0.020000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.020000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.020000 1.000 1.000 

0602255000 6B Pea, succulent 0.020000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.020000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.020000 1.000 1.000 

0603030000 6C Bean, black, seed 0.020000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.020000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.020000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.020000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.020000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.020000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.020000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.020000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.020000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.020000 1.000 1.000 

0603098000 6C Chickpea, seed 0.020000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.020000 1.000 1.000 

0603099000 6C Chickpea, flour 0.020000 1.000 1.000 

0603182000 6C Guar, seed 0.020000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.020000 1.000 1.000 

0603203000 6C Lentil, seed 0.020000 1.000 1.000 

0603256000 6C Pea, dry 0.020000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.020000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.020000 1.000 1.000 

0603348000 6C Soybean, flour 0.020000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.020000 1.000 1.000 

0801374000 8A Tomatillo 0.250000 1.000 1.000 

0801375000 8A Tomato 0.250000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.250000 1.000 1.000 

0801376000 8A Tomato, paste 0.800000 1.000 1.000 Tol.
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 17 of 32

0801376001 8A Tomato, paste-babyfood 0.800000 1.000 1.000 Tol.

0801377000 8A Tomato, puree 0.250000 1.700 1.000 

0801377001 8A Tomato, puree-babyfood 0.250000 1.700 1.000 

0801378000 8A Tomato, dried 0.250000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.250000 14.300 1.000 

0801379000 8A Tomato, juice 0.250000 1.500 1.000 

0802148000 8BC Eggplant 0.250000 1.000 1.000 

0802234000 8BC Okra 0.250000 1.000 1.000 

0802270000 8B Pepper, bell 0.250000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.250000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.250000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.250000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.250000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.250000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.250000 1.000 1.000 

0901075000 9A Cantaloupe 0.200000 1.000 1.000 

0901187000 9A Honeydew melon 0.200000 1.000 1.000 

0901399000 9A Watermelon 0.200000 1.000 1.000 

0901400000 9A Watermelon, juice 0.200000 1.000 1.000 

0902021000 9B Balsam pear 0.200000 1.000 1.000 

0902088000 9B Chayote, fruit 0.200000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.200000 1.000 1.000 

0902135000 9B Cucumber 0.200000 1.000 1.000 

0902308000 9B Pumpkin 0.200000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.200000 1.000 1.000 

0902356000 9B Squash, summer 0.200000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.200000 1.000 1.000 

0902357000 9B Squash, winter 0.200000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.200000 1.000 1.000 

1001106000 10A Citron 0.400000 1.000 1.000 D348703

1001107000 10A Citrus hybrids 0.400000 1.000 1.000 

1001108000 10A Citrus, oil 0.400000 0.600 1.000 D348272

1001240000 10A Orange 0.400000 1.000 1.000 

1001241000 10A Orange, juice 0.400000 0.600 1.000 D348272

1001241001 10A Orange, juice-babyfood 0.400000 0.600 1.000 D348272

1001242000 10A Orange, peel 0.400000 1.000 1.000 

1001369000 10A Tangerine 0.400000 1.000 1.000 

1001370000 10A Tangerine, juice 0.400000 0.600 1.000 D348272

1002197000 10B Kumquat 0.400000 1.000 1.000 

1002199000 10B Lemon 0.400000 1.000 1.000 

1002200000 10B Lemon, juice 0.400000 0.600 1.000 D348272

1002200001 10B Lemon, juice-babyfood 0.400000 0.600 1.000 D349272

1002201000 10B Lemon, peel 0.400000 1.000 1.000 

1002206000 10B Lime 0.400000 1.000 1.000 

1002207000 10B Lime, juice 0.400000 0.600 1.000 D348272

1002207001 10B Lime, juice-babyfood 0.400000 0.600 1.000 D349272

1003180000 10C Grapefruit 0.400000 1.000 1.000 

1003181000 10C Grapefruit, juice 0.400000 0.600 1.000 D349272

1003307000 10C Pummelo 0.400000 1.000 1.000 

1100007000 11 Apple, fruit with peel 0.200000 1.000 1.000 

1100008000 11 Apple, peeled fruit 0.200000 1.000 1.000 

1100008001 11 Apple, peeled fruit-babyfood 0.200000 1.000 1.000 

1100009000 11 Apple, dried 0.200000 8.000 1.000 

1100009001 11 Apple, dried-babyfood 0.200000 8.000 1.000 

1100010000 11 Apple, juice 0.200000 0.750 1.000 

1100010001 11 Apple, juice-babyfood 0.200000 0.750 1.000 

1100011000 11 Apple, sauce 0.200000 1.000 1.000 

1100011001 11 Apple, sauce-babyfood 0.200000 1.000 1.000 

1100129000 11 Crabapple 0.200000 1.000 1.000 

1100210000 11 Loquat 0.200000 1.000 1.000 

1100266000 11 Pear 0.200000 1.000 1.000 

1100266001 11 Pear-babyfood 0.200000 1.000 1.000 

1100267000 11 Pear, dried 0.200000 6.250 1.000 

1100268000 11 Pear, juice 0.200000 1.000 1.000 

1100268001 11 Pear, juice-babyfood 0.200000 1.000 1.000 

1100310000 11 Quince 0.200000 1.000 1.000 

1201090000 12A Cherry 0.500000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 18 of 32

1201090001 12A Cherry-babyfood 0.500000 1.000 1.000 

1201091000 12A Cherry, juice 0.500000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.500000 1.500 1.000 

1202012000 12B Apricot 0.500000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.500000 1.000 1.000 

1202013000 12B Apricot, dried 0.500000 6.000 1.000 

1202014000 12B Apricot, juice 0.500000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.500000 1.000 1.000 

1202230000 12B Nectarine 0.500000 1.000 1.000 

1202260000 12B Peach 0.500000 1.000 1.000 

1202260001 12B Peach-babyfood 0.500000 1.000 1.000 

1202261000 12B Peach, dried 0.500000 7.000 1.000 

1202261001 12B Peach, dried-babyfood 0.500000 7.000 1.000 

1202262000 12B Peach, juice 0.500000 1.000 1.000 

1202262001 12B Peach, juice-babyfood 0.500000 1.000 1.000 

1203285000 12C Plum 0.500000 1.000 1.000 

1203285001 12C Plum-babyfood 0.500000 1.000 1.000 

1203286000 12C Plum, prune, fresh 0.500000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.500000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.500000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.500000 5.000 1.000 

1203288000 12C Plum, prune, juice 0.500000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.500000 1.400 1.000 

1301055000 13A Blackberry 0.350000 1.000 1.000 

1301056000 13A Blackberry, juice 0.350000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 0.350000 1.000 1.000 

1301058000 13A Boysenberry 0.350000 1.000 1.000 

1301208000 13A Loganberry 0.350000 1.000 1.000 

1301320000 13A Raspberry 0.350000 1.000 1.000 

1301320001 13A Raspberry-babyfood 0.350000 1.000 1.000 

1301321000 13A Raspberry, juice 0.350000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 0.350000 1.000 1.000 

1302057000 13B Blueberry 0.300000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.300000 1.000 1.000 

1302136000 13B Currant 0.200000 1.000 1.000 

1302137000 13B Currant, dried 0.200000 1.000 1.000 

1302149000 13B Elderberry 0.200000 1.000 1.000 

1302174000 13B Gooseberry 0.200000 1.000 1.000 

1302191000 13B Huckleberry 0.200000 1.000 1.000 

1304175000 13D Grape 0.200000 1.000 1.000 

1304176000 13D Grape, juice 0.200000 1.100 1.000 D281702

1304176001 13D Grape, juice-babyfood 0.200000 1.100 1.000 

1304179000 13D Grape, wine and sherry 0.200000 1.000 1.000 

1307130000 13G Cranberry 0.020000 1.000 1.000 

1307130001 13G Cranberry-babyfood 0.020000 1.000 1.000 

1307131000 13G Cranberry, dried 0.020000 1.000 1.000 

1307132000 13G Cranberry, juice 0.020000 1.100 1.000 

1307132001 13G Cranberry, juice-babyfood 0.020000 1.100 1.000 

1307359000 13G Strawberry 0.300000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.300000 1.000 1.000 

1307360000 13G Strawberry, juice 0.300000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.300000 1.000 1.000 

1400003000 14 Almond 0.020000 1.000 1.000 

1400003001 14 Almond-babyfood 0.020000 1.000 1.000 

1400004000 14 Almond, oil 0.020000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.020000 1.000 1.000 

1400059000 14 Brazil nut 0.020000 1.000 1.000 

1400068000 14 Butternut 0.020000 1.000 1.000 

1400081000 14 Cashew 0.020000 1.000 1.000 

1400092000 14 Chestnut 0.020000 1.000 1.000 

1400155000 14 Hazelnut 0.020000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.020000 1.000 1.000 

1400185000 14 Hickory nut 0.020000 1.000 1.000 

1400213000 14 Macadamia nut 0.020000 1.000 1.000 

1400269000 14 Pecan 0.020000 1.000 1.000 

1400282000 14 Pistachio 0.020000 1.000 1.000 

1400391000 14 Walnut 0.020000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 19 of 32

1500025000 15 Barley, pearled barley 0.400000 0.300 1.000 D281702

1500025001 15 Barley, pearled barley-babyfood 0.400000 0.300 1.000 D281702

1500026000 15 Barley, flour 0.400000 0.100 1.000 D281702

1500026001 15 Barley, flour-babyfood 0.400000 0.100 1.000 D281702

1500027000 15 Barley, bran 0.400000 0.300 1.000 D281702

1500065000 15 Buckwheat 0.020000 1.000 1.000 

1500066000 15 Buckwheat, flour 0.020000 1.000 1.000 

1500120000 15 Corn, field, flour 0.020000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.020000 1.000 1.000 

1500121000 15 Corn, field, meal 0.020000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.020000 1.000 1.000 

1500122000 15 Corn, field, bran 0.020000 1.000 1.000 

1500123000 15 Corn, field, starch 0.020000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.020000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.020000 1.500 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.020000 1.500 1.000 

1500125000 15 Corn, field, oil 0.020000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.020000 1.000 1.000 

1500126000 15 Corn, pop 0.020000 1.000 1.000 

1500127000 15 Corn, sweet 0.020000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.020000 1.000 1.000 

1500226000 15 Millet, grain 0.020000 1.000 1.000 

1500231000 15 Oat, bran 0.020000 1.000 1.000 

1500232000 15 Oat, flour 0.020000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 0.020000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 0.020000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 0.020000 1.000 1.000 

1500323000 15 Rice, white 0.020000 1.000 1.000 

1500323001 15 Rice, white-babyfood 0.020000 1.000 1.000 

1500324000 15 Rice, brown 0.020000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 0.020000 1.000 1.000 

1500325000 15 Rice, flour 0.020000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 0.020000 1.000 1.000 

1500326000 15 Rice, bran 0.020000 0.900 1.000 D357449

1500326001 15 Rice, bran-babyfood 0.020000 0.900 1.000 D357449

1500328000 15 Rye, grain 0.020000 1.000 1.000 

1500329000 15 Rye, flour 0.020000 1.000 1.000 

1500344000 15 Sorghum, grain 0.020000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.020000 1.000 1.000 

1500381000 15 Triticale, flour 0.020000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 0.020000 1.000 1.000 

1500401000 15 Wheat, grain 0.020000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.020000 1.000 1.000 

1500402000 15 Wheat, flour 0.020000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.020000 1.000 1.000 

1500403000 15 Wheat, germ 0.020000 1.000 1.000 

1500404000 15 Wheat, bran 0.020000 1.000 1.000 

1500405000 15 Wild rice 0.020000 1.000 1.000 

2001163000 20A Flax seed, oil 0.020000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.020000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 0.020000 1.000 1.000 

2002330000 20B Safflower, oil 0.020000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.020000 1.000 1.000 

2002364000 20B Sunflower, seed 0.020000 1.000 1.000 

2002365000 20B Sunflower, oil 0.020000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.020000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.100000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.100000 1.000 1.000 

3100044000 31 Beef, meat 0.020000 1.000 1.000 

3100044001 31 Beef, meat-babyfood 0.020000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 

3100046000 31 Beef, meat byproducts 0.040000 1.000 1.000 

3100046001 31 Beef, meat byproducts-babyfood 0.040000 1.000 1.000 

3100048000 31 Beef, kidney 0.040000 1.000 1.000 

3100049000 31 Beef, liver 0.040000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.040000 1.000 1.000 

3200169000 32 Goat, meat 0.020000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 20 of 32

3200170000 32 Goat, meat byproducts 0.040000 1.000 1.000 

3200172000 32 Goat, kidney 0.040000 1.000 1.000 

3200173000 32 Goat, liver 0.040000 1.000 1.000 

3300189000 33 Horse, meat 0.020000 1.000 1.000 

3400290000 34 Pork, meat 0.020000 1.000 1.000 

3400290001 34 Pork, meat-babyfood 0.020000 1.000 1.000 

3400292000 34 Pork, meat byproducts 0.020000 1.000 1.000 

3400292001 34 Pork, meat byproducts-babyfood 0.020000 1.000 1.000 

3400294000 34 Pork, kidney 0.020000 1.000 1.000 

3400295000 34 Pork, liver 0.020000 1.000 1.000 

3500339000 35 Sheep, meat 0.020000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.020000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.040000 1.000 1.000 

3500342000 35 Sheep, kidney 0.040000 1.000 1.000 

3500343000 35 Sheep, liver 0.040000 1.000 1.000 

3600222000 36 Milk, fat 0.020000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.020000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.020000 1.000 1.000 

3600224000 36 Milk, water 0.020000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.020000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.020000 1.000 1.000 

3800221000 38 Meat, game 0.020000 1.000 1.000 

3900312000 39 Rabbit, meat 0.020000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.131770 1.000 1.000 D373378

8602000000 86B Water, indirect, all sources 0.131770 1.000 1.000 D373378

9500016000 O Artichoke, globe 0.450000 1.000 1.000 

9500020000 O Avocado 0.400000 1.000 1.000 

9500074000 O Canistel 0.400000 1.000 1.000 

9500089000 O Cherimoya 0.110000 1.000 1.000 

9500115000 O Coffee, roasted bean 0.200000 1.000 1.000 

9500116000 O Coffee, instant 0.200000 1.000 1.000 

9500177000 O Grape, leaves 0.200000 1.000 1.000 

9500178000 O Grape, raisin 0.300000 1.000 1.000 

9500188000 O Hop 0.100000 1.000 1.000 

9500215000 O Mango 0.400000 1.000 1.000 

9500215001 O Mango-babyfood 0.400000 1.000 1.000 

9500216000 O Mango, dried 0.400000 1.000 1.000 

9500217000 O Mango, juice 0.400000 1.000 1.000 

9500217001 O Mango, juice-babyfood 0.400000 1.000 1.000 

9500245000 O Papaya 0.400000 1.000 1.000 

9500245001 O Papaya-babyfood 0.400000 1.000 1.000 

9500246000 O Papaya, dried 0.400000 1.800 1.000 

9500247000 O Papaya, juice 0.400000 1.500 1.000 

9500263000 O Peanut 0.050000 1.000 1.000 

9500264000 O Peanut, butter 0.050000 1.890 1.000 

9500265000 O Peanut, oil 0.050000 0.310 1.000 D376367

9500275000 O Peppermint 1.500000 1.000 1.000 

9500276000 O Peppermint, oil 1.500000 0.050 1.000 

9500333000 O Sapote, Mamey 0.400000 1.000 1.000 

9500352000 O Spearmint 1.500000 1.000 1.000 

9500353000 O Spearmint, oil 1.500000 0.050 1.000 D281702
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 21 of 32

Attachment 2. Summary of the acute dietary exposure analysis for thiamethoxam.

US EPA Ver. 3.16, 03-08-d

DEEM-FCID ACUTE Analysis for THIAMETHOXAM NHANES 2003-2008 2-Day

Residue file: 060109 2010 ACUTE T+WATER.R08 Adjustment factor #2 NOT used.

Analysis Date: 09-26-2012/14:26:46 Residue file dated: 09-26-2012/09:32:49

RAC/FF intake summed over 24 hours

Run Comment: "Acute and Chronic RfDs = aPAD and cPAD"

===============================================================================

Summary calculations--per capita:

 95th Percentile 99th Percentile 99.9th Percentile

Exposure % aRfD Exposure % aRfD Exposure % aRfD 

 ---------- -------- ---------- -------- ---------- --------

Total US Population:

 0.017192 4.91 0.027541 7.87 0.048974 13.99 

All Infants:

 0.027915 7.98 0.038939 11.13 0.075416 21.55 

Children 1-2:

 0.032992 9.43 0.056203 16.06 0.091348 26.10 

Children 3-5:

 0.027008 7.72 0.043605 12.46 0.087861 25.10 

Children 6-12:

 0.017406 4.97 0.028752 8.21 0.046149 13.19 

Youth 13-19:

 0.012830 3.67 0.020081 5.74 0.034580 9.88 

Adults 20-49:

 0.016102 4.60 0.023724 6.78 0.045071 12.88 

Adults 50-99:

 0.015572 4.45 0.023018 6.58 0.034280 9.79 

Female 13-49:

 0.016655 4.76 0.025707 7.34 0.045164 12.90 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 22 of 32

Attachment 3. Input File for the Chronic Dietary Exposure Estimates.

Filename: C:\Documents and Settings\dmcneill\My Documents\Thiamethoxam5\060109 2010 

T+FHE+WATER.R08

Chemical: thiamethoxam

RfD(Chronic): .012 mg/kg bw/day NOEL(Chronic): 0 mg/kg bw/day

RfD(Acute): .35 mg/kg bw/day NOEL(Acute): 0 mg/kg bw/day

Date created/last modified: 09-26-2012/08:05:29 Program ver. 3.16, 03-08-d

Comment: Acute and Chronic RfDs = aPAD and cPAD

-----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Commodity Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

0101050000 1AB Beet, garden, roots 0.050000 1.000 1.000 

0101050001 1AB Beet, garden, roots-babyfood 0.050000 1.000 1.000 

0101052000 1A Beet, sugar 0.050000 1.000 1.000 

0101052001 1A Beet, sugar-babyfood 0.050000 1.000 1.000 

0101053000 1A Beet, sugar, molasses 0.050000 1.000 1.000 

0101053001 1A Beet, sugar, molasses-babyfood 0.050000 1.000 1.000 

0101067000 1AB Burdock 0.050000 1.000 1.000 

0101078000 1AB Carrot 0.050000 1.000 1.000 

0101078001 1AB Carrot-babyfood 0.050000 1.000 1.000 

0101079000 1AB Carrot, juice 0.050000 1.000 1.000 

0101084000 1AB Celeriac 0.050000 1.000 1.000 

0101100000 1AB Chicory, roots 0.050000 1.000 1.000 

0101168000 1AB Ginseng, dried 0.050000 1.000 1.000 

0101190000 1AB Horseradish 0.050000 1.000 1.000 

0101250000 1AB Parsley, turnip rooted 0.050000 1.000 1.000 

0101251000 1AB Parsnip 0.050000 1.000 1.000 

0101251001 1AB Parsnip-babyfood 0.050000 1.000 1.000 

0101314000 1AB Radish, roots 0.050000 1.000 1.000 

0101316000 1AB Radish, Oriental, roots 0.050000 1.000 1.000 

0101327000 1AB Rutabaga 0.050000 1.000 1.000 

0101331000 1AB Salsify, roots 0.050000 1.000 1.000 

0101388000 1AB Turnip, roots 0.050000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.010000 1.000 1.000 FHE

0103015001 1CD Arrowroot, flour-babyfood 0.010000 1.000 1.000 FHE

0103017000 1CD Artichoke, Jerusalem 0.010000 1.000 1.000 FHE

0103082000 1CD Cassava 0.010000 1.000 1.000 FHE

0103082001 1CD Cassava-babyfood 0.010000 1.000 1.000 FHE

0103139000 1CD Dasheen, corm 0.010000 1.000 1.000 FHE

0103166000 1CD Ginger 0.010000 1.000 1.000 FHE

0103166001 1CD Ginger-babyfood 0.010000 1.000 1.000 FHE

0103167000 1CD Ginger, dried 0.010000 1.000 1.000 FHE

0103296000 1C Potato, chips 0.250000 1.200 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.250000 1.700 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.250000 1.700 1.000 

0103298000 1C Potato, flour 0.250000 1.700 1.000 

0103298001 1C Potato, flour-babyfood 0.250000 1.700 1.000 

0103299000 1C Potato, tuber, w/peel 0.250000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.250000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.250000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.250000 1.000 1.000 

0103366000 1CD Sweet potato 0.020000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.020000 1.000 1.000 

0103371000 1CD Tanier, corm 0.020000 1.000 1.000 

0103387000 1CD Turmeric 0.250000 1.000 1.000 

0103406000 1CD Yam, true 0.020000 1.000 1.000 

0103407000 1CD Yam bean 0.020000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 23 of 32

0200051000 2 Beet, garden, tops 0.010000 1.000 1.000 FHE

0200101000 2 Chicory, tops 0.010000 1.000 1.000 FHE

0200140000 2 Dasheen, leaves 0.010000 1.000 1.000 FHE

0200315000 2 Radish, tops 0.010000 1.000 1.000 FHE

0200317000 2 Radish, Oriental, tops 0.010000 1.000 1.000 FHE

0200332000 2 Salsify, tops 0.010000 1.000 1.000 FHE

0301165000 3A Garlic, bulb 0.010000 1.000 1.000 FHE

0301165001 3A Garlic, bulb-babyfood 0.010000 1.000 1.000 FHE

0301237000 3A Onion, bulb 0.030000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.030000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.030000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.030000 9.000 1.000 

0301338000 3A Shallot, bulb 0.000000 1.000 1.000 

0302103000 3B Chive, fresh leaves 0.010000 1.000 1.000 FHE

0302198000 3B Leek 0.010000 1.000 1.000 FHE

0302239000 3B Onion, green 0.010000 1.000 1.000 FHE

0302338500 3B Shallot, fresh leaves 0.010000 1.000 1.000 FHE

0401005000 4A Amaranth, leafy 4.000000 1.000 1.000 

0401018000 4A Arugula 4.000000 1.000 1.000 

0401104000 4A Chrysanthemum, garland 4.000000 1.000 1.000 

0401133000 4A Cress, garden 4.000000 1.000 1.000 

0401134000 4A Cress, upland 4.000000 1.000 1.000 

0401138000 4A Dandelion, leaves 4.000000 1.000 1.000 

0401150000 4A Endive 4.000000 1.000 1.000 

0401204000 4A Lettuce, head 4.000000 1.000 1.000 

0401205000 4A Lettuce, leaf 4.000000 1.000 1.000 

0401248000 4A Parsley, leaves 4.000000 1.000 1.000 

0401313000 4A Radicchio 4.000000 1.000 1.000 

0401355000 4A Spinach 4.000000 1.000 1.000 

0401355001 4A Spinach-babyfood 4.000000 1.000 1.000 

0402076000 4B Cardoon 4.000000 1.000 1.000 

0402085000 4B Celery 4.000000 1.000 1.000 

0402085001 4B Celery-babyfood 4.000000 1.000 1.000 

0402086000 4B Celery, juice 4.000000 1.000 1.000 

0402087000 4B Celtuce 4.000000 1.000 1.000 

0402152000 4B Fennel, Florence 4.000000 1.000 1.000 

0402322000 4B Rhubarb 4.000000 1.000 1.000 

0402367000 4B Swiss chard 4.000000 1.000 1.000 

0501061000 5A Broccoli 0.980000 1.000 1.000 D281702

0501061001 5A Broccoli-babyfood 0.980000 1.000 1.000 

0501062000 5A Broccoli, Chinese 0.980000 1.000 1.000 

0501064000 5A Brussels sprouts 0.980000 1.000 1.000 

0501069000 5A Cabbage 0.980000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.980000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.980000 1.000 1.000 

0501083000 5A Cauliflower 0.980000 1.000 1.000 

0501196000 5A Kohlrabi 0.980000 1.000 1.000 

0502063000 5B Broccoli raab 0.820000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 0.820000 1.000 1.000 D281702

0502117000 5B Collards 0.820000 1.000 1.000 

0502194000 5B Kale 0.820000 1.000 1.000 

0502229000 5B Mustard greens 0.820000 1.000 1.000 

0502318000 5B Rape greens 0.820000 1.000 1.000 

0502389000 5B Turnip, greens 0.820000 1.000 1.000 

0600347000 6 Soybean, seed 0.010000 1.000 1.000 D281702

0600349000 6 Soybean, soy milk 0.010000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.010000 1.000 1.000 

0600350000 6 Soybean, oil 0.010000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.010000 1.000 1.000 

0601043000 6A Bean, snap, succulent 0.010000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 24 of 32

0601043001 6A Bean, snap, succulent-babyfood 0.010000 1.000 1.000 

0601257000 6A Pea, edible podded, succulent 0.010000 1.000 1.000 

0601349500 6AB Soybean, vegetable 0.000000 1.000 1.000 

0602031000 6B Bean, broad, succulent 0.010000 1.000 1.000 

0602033000 6B Bean, cowpea, succulent 0.010000 1.000 1.000 

0602037000 6B Bean, lima, succulent 0.010000 1.000 1.000 

0602255000 6B Pea, succulent 0.010000 1.000 1.000 

0602255001 6B Pea, succulent-babyfood 0.010000 1.000 1.000 

0602259000 6B Pea, pigeon, succulent 0.010000 1.000 1.000 

0603030000 6C Bean, black, seed 0.010000 1.000 1.000 

 Full comment: S,. Tayayin, 26 Nov 2002

0603032000 6C Bean, broad, seed 0.010000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.010000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.010000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.010000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.010000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.010000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.010000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.010000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.010000 1.000 1.000 

0603098000 6C Chickpea, seed 0.010000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.010000 1.000 1.000 

0603099000 6C Chickpea, flour 0.010000 1.000 1.000 

0603182000 6C Guar, seed 0.010000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.010000 1.000 1.000 

0603203000 6C Lentil, seed 0.010000 1.000 1.000 

0603256000 6C Pea, dry 0.010000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.010000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.010000 1.000 1.000 

0603348000 6C Soybean, flour 0.010000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.010000 1.000 1.000 

0801374000 8A Tomatillo 0.080000 1.000 1.000 

0801375000 8A Tomato 0.080000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.080000 1.000 1.000 

0801376000 8A Tomato, paste 0.080000 3.800 1.000 D265079

0801376001 8A Tomato, paste-babyfood 0.080000 3.800 1.000 

0801377000 8A Tomato, puree 0.080000 1.700 1.000 D265079

0801377001 8A Tomato, puree-babyfood 0.080000 1.700 1.000 

0801378000 8A Tomato, dried 0.080000 14.300 1.000 

0801378001 8A Tomato, dried-babyfood 0.080000 14.300 1.000 

0801379000 8A Tomato, juice 0.080000 1.500 1.000 

0801380000 8A Tomato, Tree 0.010000 1.000 1.000 FHE

0802148000 8BC Eggplant 0.080000 1.000 1.000 

 Full comment: D281702, tomato

0802234000 8BC Okra 0.080000 1.000 1.000 

0802270000 8B Pepper, bell 0.080000 1.000 1.000 

 Full comment: D281702, pepper 

0802270001 8B Pepper, bell-babyfood 0.080000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.080000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.080000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.080000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.080000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.080000 1.000 1.000 

0901075000 9A Cantaloupe 0.200000 1.000 1.000 

0901187000 9A Honeydew melon 0.200000 1.000 1.000 

0901399000 9A Watermelon 0.200000 1.000 1.000 

0901400000 9A Watermelon, juice 0.200000 1.000 1.000 

0902021000 9B Balsam pear 0.200000 1.000 1.000 

0902088000 9B Chayote, fruit 0.200000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.200000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 25 of 32

0902135000 9B Cucumber 0.200000 1.000 1.000 

0902308000 9B Pumpkin 0.200000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.200000 1.000 1.000 

0902356000 9B Squash, summer 0.200000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.200000 1.000 1.000 

0902357000 9B Squash, winter 0.200000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.200000 1.000 1.000 

1001106000 10A Citron 0.100000 1.000 1.000 

1001107000 10A Citrus hybrids 0.100000 1.000 1.000 

1001108000 10A Citrus, oil 0.100000 0.600 1.000 

1001240000 10A Orange 0.100000 1.000 1.000 

1001241000 10A Orange, juice 0.100000 0.600 1.000 

1001241001 10A Orange, juice-babyfood 0.100000 0.600 1.000 

1001242000 10A Orange, peel 0.100000 1.000 1.000 

1001369000 10A Tangerine 0.100000 1.000 1.000 

1001370000 10A Tangerine, juice 0.100000 0.600 1.000 

1002197000 10B Kumquat 0.400000 1.000 1.000 

1002199000 10B Lemon 0.090000 1.000 1.000 

1002200000 10B Lemon, juice 0.090000 0.600 1.000 

1002200001 10B Lemon, juice-babyfood 0.090000 0.600 1.000 

1002201000 10B Lemon, peel 0.090000 1.000 1.000 

1002206000 10B Lime 0.100000 1.000 1.000 

1002207000 10B Lime, juice 0.100000 2.000 1.000 

1002207001 10B Lime, juice-babyfood 0.100000 2.000 1.000 

1003180000 10C Grapefruit 0.070000 1.000 1.000 

1003181000 10C Grapefruit, juice 0.070000 0.600 1.000 

1003307000 10C Pummelo 0.100000 1.000 1.000 

1100007000 11 Apple, fruit with peel 0.060000 1.000 1.000 

 Full comment: D281702 & D265079

1100008000 11 Apple, peeled fruit 0.060000 1.000 1.000 

1100008001 11 Apple, peeled fruit-babyfood 0.060000 1.000 1.000 

1100009000 11 Apple, dried 0.060000 8.000 1.000 

1100009001 11 Apple, dried-babyfood 0.060000 8.000 1.000 

1100010000 11 Apple, juice 0.060000 0.750 1.000 

1100010001 11 Apple, juice-babyfood 0.060000 0.750 1.000 

1100011000 11 Apple, sauce 0.060000 1.000 1.000 

1100011001 11 Apple, sauce-babyfood 0.060000 1.000 1.000 

1100129000 11 Crabapple 0.060000 1.000 1.000 

1100173500 11 Goji berry 0.000000 1.000 1.000 

1100210000 11 Loquat 0.060000 1.000 1.000 

1100266000 11 Pear 0.060000 1.000 1.000 

1100266001 11 Pear-babyfood 0.060000 1.000 1.000 

1100267000 11 Pear, dried 0.060000 6.250 1.000 

1100268000 11 Pear, juice 0.060000 0.750 1.000 

1100268001 11 Pear, juice-babyfood 0.060000 0.750 1.000 

1100310000 11 Quince 0.060000 1.000 1.000 

1201090000 12A Cherry 0.210000 1.000 1.000 

1201090001 12A Cherry-babyfood 0.210000 1.000 1.000 

1201091000 12A Cherry, juice 0.210000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.210000 1.500 1.000 

1202012000 12B Apricot 0.070000 1.000 1.000 

 Full comment: W. Cuthchin 12/10/03 DERs

1202012001 12B Apricot-babyfood 0.070000 1.000 1.000 

1202013000 12B Apricot, dried 0.070000 6.000 1.000 

1202014000 12B Apricot, juice 0.070000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.070000 1.000 1.000 

1202230000 12B Nectarine 0.070000 1.000 1.000 

1202260000 12B Peach 0.070000 1.000 1.000 

1202260001 12B Peach-babyfood 0.070000 1.000 1.000 

1202261000 12B Peach, dried 0.070000 7.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 26 of 32

1202261001 12B Peach, dried-babyfood 0.070000 7.000 1.000 

1202262000 12B Peach, juice 0.070000 1.000 1.000 

1202262001 12B Peach, juice-babyfood 0.070000 1.000 1.000 

1203285000 12C Plum 0.071000 1.000 1.000 

1203285001 12C Plum-babyfood 0.071000 1.000 1.000 

1203286000 12C Plum, prune, fresh 0.071000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.071000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.071000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.071000 5.000 1.000 

1203288000 12C Plum, prune, juice 0.071000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.071000 1.400 1.000 

1301055000 13A Blackberry 0.120000 1.000 1.000 D281702

1301056000 13A Blackberry, juice 0.120000 1.000 1.000 

1301056001 13A Blackberry, juice-babyfood 0.120000 1.000 1.000 

1301058000 13A Boysenberry 0.120000 1.000 1.000 

1301208000 13A Loganberry 0.120000 1.000 1.000 

1301320000 13A Raspberry 0.120000 1.000 1.000 

1301320001 13A Raspberry-babyfood 0.120000 1.000 1.000 

1301321000 13A Raspberry, juice 0.120000 1.000 1.000 

1301321001 13A Raspberry, juice-babyfood 0.120000 1.000 1.000 

1302057000 13B Blueberry 0.300000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.300000 1.000 1.000 

1302136000 13B Currant 0.200000 1.000 1.000 

1302137000 13B Currant, dried 0.200000 1.000 1.000 

1302149000 13B Elderberry 0.200000 1.000 1.000 

1302174000 13B Gooseberry 0.200000 1.000 1.000 

1302191000 13B Huckleberry 0.200000 1.000 1.000 

1303227000 13C Mulberry 0.010000 1.000 1.000 FHE

1304175000 13D Grape 0.060000 1.000 1.000 D281702

1304176000 13D Grape, juice 0.060000 1.100 1.000 

1304176001 13D Grape, juice-babyfood 0.060000 1.100 1.000 

1304179000 13D Grape, wine and sherry 0.060000 1.000 1.000 

1304195000 13D Kiwifruit, fuzzy 0.010000 1.000 1.000 FHE

1307130000 13G Cranberry 0.020000 1.000 1.000 

1307130001 13G Cranberry-babyfood 0.020000 1.000 1.000 

1307131000 13G Cranberry, dried 0.020000 1.000 1.000 

1307132000 13G Cranberry, juice 0.020000 1.100 1.000 

1307132001 13G Cranberry, juice-babyfood 0.020000 1.100 1.000 

1307359000 13G Strawberry 0.300000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.300000 1.000 1.000 

1307360000 13G Strawberry, juice 0.300000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.300000 1.000 1.000 

1400003000 14 Almond 0.010000 1.000 1.000 D349272

1400003001 14 Almond-babyfood 0.010000 1.000 1.000 

1400004000 14 Almond, oil 0.010000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.010000 1.000 1.000 

1400059000 14 Brazil nut 0.010000 1.000 1.000 

1400068000 14 Butternut 0.010000 1.000 1.000 

1400081000 14 Cashew 0.010000 1.000 1.000 

1400092000 14 Chestnut 0.010000 1.000 1.000 

1400155000 14 Hazelnut 0.010000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.010000 1.000 1.000 

1400185000 14 Hickory nut 0.010000 1.000 1.000 

1400213000 14 Macadamia nut 0.010000 1.000 1.000 

1400269000 14 Pecan 0.010000 1.000 1.000 

1400278000 14 Pine nut 0.010000 1.000 1.000 FHE

1400282000 14 Pistachio 0.010000 1.000 1.000 

1400391000 14 Walnut 0.010000 1.000 1.000 

1500025000 15 Barley, pearled barley 0.086000 0.300 1.000 

 Full comment: D281702/D325447
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 27 of 32

1500025001 15 Barley, pearled barley-babyfood 0.086000 0.300 1.000 

1500026000 15 Barley, flour 0.086000 0.100 1.000 

1500026001 15 Barley, flour-babyfood 0.086000 0.100 1.000 

1500027000 15 Barley, bran 0.086000 0.300 1.000 

1500065000 15 Buckwheat 0.020000 1.000 1.000 

1500066000 15 Buckwheat, flour 0.020000 1.000 1.000 

1500120000 15 Corn, field, flour 0.020000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.020000 1.000 1.000 

1500121000 15 Corn, field, meal 0.020000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.020000 1.000 1.000 

1500122000 15 Corn, field, bran 0.020000 1.000 1.000 

1500123000 15 Corn, field, starch 0.020000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.020000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.020000 1.500 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.020000 1.500 1.000 

1500125000 15 Corn, field, oil 0.020000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.020000 1.000 1.000 

1500126000 15 Corn, pop 0.020000 1.000 1.000 

1500127000 15 Corn, sweet 0.020000 1.000 1.000 

1500127001 15 Corn, sweet-babyfood 0.020000 1.000 1.000 

1500226000 15 Millet, grain 0.020000 1.000 1.000 

1500231000 15 Oat, bran 0.020000 1.000 1.000 

1500232000 15 Oat, flour 0.020000 1.000 1.000 

1500232001 15 Oat, flour-babyfood 0.020000 1.000 1.000 

1500233000 15 Oat, groats/rolled oats 0.020000 1.000 1.000 

1500233001 15 Oat, groats/rolled oats-babyfood 0.020000 1.000 1.000 

1500323000 15 Rice, white 0.010000 1.000 1.000 

1500323001 15 Rice, white-babyfood 0.010000 1.000 1.000 

1500324000 15 Rice, brown 0.010000 1.000 1.000 

1500324001 15 Rice, brown-babyfood 0.010000 1.000 1.000 

1500325000 15 Rice, flour 0.010000 1.000 1.000 

1500325001 15 Rice, flour-babyfood 0.010000 1.000 1.000 

1500326000 15 Rice, bran 0.010000 0.900 1.000 

1500326001 15 Rice, bran-babyfood 0.010000 0.900 1.000 

1500328000 15 Rye, grain 0.020000 1.000 1.000 

1500329000 15 Rye, flour 0.020000 1.000 1.000 

1500344000 15 Sorghum, grain 0.020000 1.000 1.000 

1500345000 15 Sorghum, syrup 0.020000 1.000 1.000 

1500381000 15 Triticale, flour 0.020000 1.000 1.000 

1500381001 15 Triticale, flour-babyfood 0.020000 1.000 1.000 

1500401000 15 Wheat, grain 0.020000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.020000 1.000 1.000 

1500402000 15 Wheat, flour 0.020000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.020000 1.000 1.000 

1500403000 15 Wheat, germ 0.020000 1.000 1.000 

1500404000 15 Wheat, bran 0.020000 1.000 1.000 

1500405000 15 Wild rice 0.020000 1.000 1.000 

1800002000 18 Alfalfa, seed 0.010000 1.000 1.000 FHE

1901028000 19A Basil, fresh leaves 0.010000 1.000 1.000 FHE

1901028001 19A Basil, fresh leaves-babyfood 0.010000 1.000 1.000 FHE

1901029000 19A Basil, dried leaves 0.010000 1.000 1.000 FHE

1901029001 19A Basil, dried leaves-babyfood 0.010000 1.000 1.000 FHE

1901102500 19A Chive, dried leaves 0.000000 1.000 1.000 

1901118000 19A Cilantro, leaves 0.010000 1.000 1.000 FHE

1901118001 19A Cilantro, leaves-babyfood 0.010000 1.000 1.000 FHE

1901144000 19A Dillweed 0.010000 1.000 1.000 FHE

1901184000 19A Herbs, other 0.010000 1.000 1.000 FHE

1901184001 19A Herbs, other-babyfood 0.010000 1.000 1.000 FHE

1901202000 19A Lemongrass 0.010000 1.000 1.000 FHE

1901220000 19A Marjoram 0.010000 1.000 1.000 FHE
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 28 of 32

1901220001 19A Marjoram-babyfood 0.010000 1.000 1.000 FHE

1901249000 19A Parsley, dried leaves 0.010000 1.000 1.000 FHE

1901249001 19A Parsley, dried leaves-babyfood 0.010000 1.000 1.000 FHE

1901334000 19A Savory 0.010000 1.000 1.000 FHE

1902105000 19B Cinnamon 0.010000 1.000 1.000 FHE

1902105001 19B Cinnamon-babyfood 0.010000 1.000 1.000 FHE

1902119000 19B Coriander, seed 0.010000 1.000 1.000 FHE

1902119001 19B Coriander, seed-babyfood 0.010000 1.000 1.000 FHE

1902143000 19B Dill, seed 0.010000 1.000 1.000 FHE

1902274000 19B Pepper, black and white 0.010000 1.000 1.000 FHE

1902274001 19B Pepper, black and white-babyfood 0.010000 1.000 1.000 FHE

1902354000 19B Spices, other 0.010000 1.000 1.000 FHE

1902354001 19B Spices, other-babyfood 0.010000 1.000 1.000 FHE

2001163000 20A Flax seed, oil 0.020000 1.000 1.000 Tol.

2001319000 20A Rapeseed, oil 0.020000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 0.020000 1.000 1.000 

2001336000 20A Sesame, seed 0.010000 1.000 1.000 FHE

2001336001 20A Sesame, seed-babyfood 0.010000 1.000 1.000 FHE

2001337000 20A Sesame, oil 0.010000 1.000 1.000 FHE

2001337001 20A Sesame, oil-babyfood 0.010000 1.000 1.000 FHE

2002330000 20B Safflower, oil 0.020000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.020000 1.000 1.000 

2002364000 20B Sunflower, seed 0.020000 1.000 1.000 

2002365000 20B Sunflower, oil 0.020000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.020000 1.000 1.000 

2003114001 20C Coconut, oil-babyfood 0.010000 1.000 1.000 FHE

2003128000 20C Cottonseed, oil 0.100000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.100000 1.000 1.000 

2100228000 21 Mushroom 0.010000 1.000 1.000 FHE

3100044000 31 Beef, meat 0.020000 1.000 1.000 

3100044001 31 Beef, meat-babyfood 0.020000 1.000 1.000 

3100045000 31 Beef, meat, dried 0.020000 1.920 1.000 

3100046000 31 Beef, meat byproducts 0.040000 1.000 1.000 Rec.Tol.

3100046001 31 Beef, meat byproducts-babyfood 0.040000 1.000 1.000 

3100047000 31 Beef, fat 0.010000 1.000 1.000 FHE

3100047001 31 Beef, fat-babyfood 0.010000 1.000 1.000 FHE

3100048000 31 Beef, kidney 0.040000 1.000 1.000 

3100049000 31 Beef, liver 0.040000 1.000 1.000 

3100049001 31 Beef, liver-babyfood 0.040000 1.000 1.000 

3200169000 32 Goat, meat 0.020000 1.000 1.000 

3200170000 32 Goat, meat byproducts 0.040000 1.000 1.000 Rec. Tol.

3200171000 32 Goat, fat 0.005000 1.000 1.000 FHE

3200172000 32 Goat, kidney 0.040000 1.000 1.000 

3200173000 32 Goat, liver 0.040000 1.000 1.000 

3300189000 33 Horse, meat 0.020000 1.000 1.000 

3400290000 34 Pork, meat 0.020000 1.000 1.000 

3400290001 34 Pork, meat-babyfood 0.020000 1.000 1.000 

3400291000 34 Pork, skin 0.010000 1.000 1.000 FHE

3400292000 34 Pork, meat byproducts 0.020000 1.000 1.000 

3400292001 34 Pork, meat byproducts-babyfood 0.020000 1.000 1.000 

3400293000 34 Pork, fat 0.010000 1.000 1.000 FHE

3400293001 34 Pork, fat-babyfood 0.010000 1.000 1.000 FHE

3400294000 34 Pork, kidney 0.020000 1.000 1.000 

3400295000 34 Pork, liver 0.020000 1.000 1.000 

3500339000 35 Sheep, meat 0.020000 1.000 1.000 

3500339001 35 Sheep, meat-babyfood 0.020000 1.000 1.000 

3500340000 35 Sheep, meat byproducts 0.040000 1.000 1.000 

3500341000 35 Sheep, fat 0.010000 1.000 1.000 FHE

3500341001 35 Sheep, fat-babyfood 0.010000 1.000 1.000 FHE

3500342000 35 Sheep, kidney 0.040000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 29 of 32

3500343000 35 Sheep, liver 0.040000 1.000 1.000 

3600222000 36 Milk, fat 0.020000 1.000 1.000 

3600222001 36 Milk, fat-baby food/infant formu 0.020000 1.000 1.000 

3600223000 36 Milk, nonfat solids 0.020000 1.000 1.000 

3600223001 36 Milk, nonfat solids-baby food/in 0.020000 1.000 1.000 

3600224000 36 Milk, water 0.020000 1.000 1.000 

3600224001 36 Milk, water-babyfood/infant form 0.020000 1.000 1.000 

3600225001 36 Milk, sugar (lactose)-baby food/ 0.020000 1.000 1.000 

3800221000 38 Meat, game 0.020000 1.000 1.000 

3900312000 39 Rabbit, meat 0.020000 1.000 1.000 

4000093000 40 Chicken, meat 0.010000 1.000 1.000 FHE

4000093001 40 Chicken, meat-babyfood 0.010000 1.000 1.000 FHE

4000094000 40 Chicken, liver 0.010000 1.000 1.000 FHE

4000095000 40 Chicken, meat byproducts 0.010000 1.000 1.000 FHE

4000095001 40 Chicken, meat byproducts-babyfoo 0.010000 1.000 1.000 FHE

4000096000 40 Chicken, fat 0.010000 1.000 1.000 FHE

4000096001 40 Chicken, fat-babyfood 0.010000 1.000 1.000 FHE

4000097000 40 Chicken, skin 0.010000 1.000 1.000 FHE

4000097001 40 Chicken, skin-babyfood 0.010000 1.000 1.000 FHE

5000382000 50 Turkey, meat 0.010000 1.000 1.000 FHE

5000382001 50 Turkey, meat-babyfood 0.010000 1.000 1.000 FHE

5000383000 50 Turkey, liver 0.010000 1.000 1.000 FHE

5000383001 50 Turkey, liver-babyfood 0.010000 1.000 1.000 FHE

5000384000 50 Turkey, meat byproducts 0.010000 1.000 1.000 FHE

5000384001 50 Turkey, meat byproducts-babyfood 0.010000 1.000 1.000 FHE

5000385000 50 Turkey, fat 0.010000 1.000 1.000 FHE

5000385001 50 Turkey, fat-babyfood 0.010000 1.000 1.000 FHE

5000386000 50 Turkey, skin 0.010000 1.000 1.000 FHE

5000386001 50 Turkey, skin-babyfood 0.010000 1.000 1.000 FHE

6000301000 60 Poultry, other, meat 0.010000 1.000 1.000 FHE

6000302000 60 Poultry, other, liver 0.010000 1.000 1.000 FHE

6000303000 60 Poultry, other, meat byproducts 0.010000 1.000 1.000 FHE

6000304000 60 Poultry, other, fat 0.010000 1.000 1.000 FHE

6000305000 60 Poultry, other, skin 0.010000 1.000 1.000 FHE

7000145000 70 Egg, whole 0.010000 1.000 1.000 FHE

7000145001 70 Egg, whole-babyfood 0.010000 1.000 1.000 FHE

7000146000 70 Egg, white 0.010000 1.000 1.000 FHE

7000146001 70 Egg, white (solids)-babyfood 0.010000 1.000 1.000 FHE

7000147000 70 Egg, yolk 0.010000 1.000 1.000 FHE

7000147001 70 Egg, yolk-babyfood 0.010000 1.000 1.000 FHE

8000157000 80 Fish-freshwater finfish 0.010000 1.000 1.000 FHE

8000158000 80 Fish-freshwater finfish, farm ra 0.010000 1.000 1.000 FHE

8000159000 80 Fish-saltwater finfish, tuna 0.010000 1.000 1.000 FHE

8000160000 80 Fish-saltwater finfish, other 0.010000 1.000 1.000 FHE

8000161000 80 Fish-shellfish, crustacean 0.010000 1.000 1.000 FHE

8000162000 80 Fish-shellfish, mollusc 0.010000 1.000 1.000 FHE

8601000000 86A Water, direct, all sources 0.011310 1.000 1.000 

8601100000 86A Water, direct, tap 0.000000 1.000 1.000 

8601200000 86A Water, direct, bottled 0.000000 1.000 1.000 

8601300000 86A Water, direct, other 0.000000 1.000 1.000 

8601400000 86A Water, direct, source-NS 0.000000 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.011310 1.000 1.000 

8602100000 86B Water, indirect, tap 0.000000 1.000 1.000 

8602200000 86B Water, indirect, bottled 0.000000 1.000 1.000 

8602300000 86B Water, indirect, other 0.000000 1.000 1.000 

8602400000 86B Water, indirect, source-NS 0.000000 1.000 1.000 

9500000500 O Acai berry 0.000000 1.000 1.000 

9500001000 O Acerola 0.010000 1.000 1.000 FHE

9500001500 O Agave 0.000000 1.000 1.000 

9500006000 O Amaranth, grain 0.010000 1.000 1.000 FHE
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 30 of 32

9500016000 O Artichoke, globe 0.190000 1.000 1.000 

 Full comment: D281702/D325447

9500019000 O Asparagus 0.010000 1.000 1.000 FHE

9500019500 O Atemoya 0.000000 1.000 1.000 

9500020000 O Avocado 0.110000 1.000 1.000 

 Full comment: D357449/D357450

9500022000 O Bamboo, shoots 0.010000 1.000 1.000 FHE

9500023000 O Banana 0.010000 1.000 1.000 FHE

9500023001 O Banana-babyfood 0.010000 1.000 1.000 FHE

9500024000 O Banana, dried 0.010000 1.000 1.000 FHE

9500024001 O Banana, dried-babyfood 0.010000 1.000 1.000 FHE

9500054000 O Belgium endive 0.010000 1.000 1.000 FHE

9500060000 O Breadfruit 0.010000 1.000 1.000 FHE

9500073000 O Cactus 0.010000 1.000 1.000 FHE

9500074000 O Canistel 0.400000 1.000 1.000 

9500077000 O Carob 0.010000 1.000 1.000 FHE

9500089000 O Cherimoya 0.110000 1.000 1.000 

9500109000 O Cocoa bean, chocolate 0.010000 1.000 1.000 FHE

9500110000 O Cocoa bean, powder 0.010000 1.000 1.000 FHE

9500111000 O Coconut, meat 0.010000 1.000 1.000 FHE

9500111001 O Coconut, meat-babyfood 0.010000 1.000 1.000 FHE

9500112000 O Coconut, dried 0.010000 1.000 1.000 FHE

9500113000 O Coconut, milk 0.010000 1.000 1.000 FHE

9500114000 O Coconut, oil 0.010000 1.000 1.000 FHE

9500115000 O Coffee, roasted bean 0.200000 1.000 1.000 

9500116000 O Coffee, instant 0.200000 1.000 1.000 

9500141000 O Date 0.010000 1.000 1.000 FHE

9500151000 O Feijoa 0.010000 1.000 1.000 FHE

9500153000 O Fig 0.010000 1.000 1.000 FHE

9500154000 O Fig, dried 0.010000 1.000 1.000 FHE

9500177000 O Grape, leaves 0.200000 1.000 1.000 

9500178000 O Grape, raisin 0.060000 2.300 1.000 

 Full comment: D281702

9500183000 O Guava 0.010000 1.000 1.000 FHE

9500183001 O Guava-babyfood 0.010000 1.000 1.000 FHE

9500186000 O Honey 0.010000 1.000 1.000 FHE

9500186001 O Honey-babyfood 0.010000 1.000 1.000 FHE

9500188000 O Hop 0.100000 1.000 1.000 

9500193000 O Jackfruit 0.010000 1.000 1.000 FHE

9500209000 O Longan 0.010000 1.000 1.000 FHE

9500211000 O Lychee 0.010000 1.000 1.000 FHE

9500212000 O Lychee, dried 0.010000 1.000 1.000 FHE

9500214000 O Mamey apple 0.010000 1.000 1.000 FHE

9500215000 O Mango 0.110000 1.000 1.000 

 Full comment: D357449, avacado

9500215001 O Mango-babyfood 0.110000 1.000 1.000 

9500216000 O Mango, dried 0.110000 1.000 1.000 

9500217000 O Mango, juice 0.110000 1.000 1.000 

9500217001 O Mango, juice-babyfood 0.110000 1.000 1.000 

9500218000 O Maple, sugar 0.010000 1.000 1.000 FHE

9500219000 O Maple syrup 0.010000 1.000 1.000 FHE

9500235000 O Olive 0.010000 1.000 1.000 FHE

9500236000 O Olive, oil 0.010000 1.000 1.000 FHE

9500243000 O Palm heart, leaves 0.010000 1.000 1.000 FHE

9500244000 O Palm, oil 0.010000 1.000 1.000 FHE

9500244001 O Palm, oil-babyfood 0.010000 1.000 1.000 FHE

9500245000 O Papaya 0.110000 1.000 1.000 

9500245001 O Papaya-babyfood 0.110000 1.000 1.000 

9500246000 O Papaya, dried 0.110000 1.800 1.000 

9500247000 O Papaya, juice 0.110000 1.500 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 31 of 32

9500252000 O Passionfruit 0.010000 1.000 1.000 FHE

9500252001 O Passionfruit-babyfood 0.010000 1.000 1.000 FHE

9500253000 O Passionfruit, juice 0.010000 1.000 1.000 FHE

9500253001 O Passionfruit, juice-babyfood 0.010000 1.000 1.000 FHE

9500254000 O Pawpaw 0.010000 1.000 1.000 FHE

9500263000 O Peanut 0.050000 1.000 1.000 

9500264000 O Peanut, butter 0.050000 1.890 1.000 

9500265000 O Peanut, oil 0.050000 0.310 1.000 

9500275000 O Peppermint 1.500000 1.000 1.000 

9500276000 O Peppermint, oil 1.500000 0.050 1.000 

9500277000 O Persimmon 0.010000 1.000 1.000 FHE

9500279000 O Pineapple 0.010000 1.000 1.000 FHE

9500279001 O Pineapple-babyfood 0.010000 1.000 1.000 FHE

9500280000 O Pineapple, dried 0.010000 1.000 1.000 FHE

9500281000 O Pineapple, juice 0.010000 1.000 1.000 FHE

9500281001 O Pineapple, juice-babyfood 0.010000 1.000 1.000 FHE

9500283000 O Plantain 0.010000 1.000 1.000 FHE

9500284000 O Plantain, dried 0.010000 1.000 1.000 FHE

9500289000 O Pomegranate 0.010000 1.000 1.000 FHE

9500306000 O Psyllium, seed 0.010000 1.000 1.000 FHE

9500311000 O Quinoa, grain 0.010000 1.000 1.000 FHE

9500333000 O Sapote, Mamey 0.400000 1.000 1.000 

9500335000 O Seaweed 0.010000 1.000 1.000 FHE

9500335001 O Seaweed-babyfood 0.010000 1.000 1.000 FHE

9500346000 O Soursop 0.010000 1.000 1.000 FHE

9500351000 O Spanish lime 0.010000 1.000 1.000 FHE

9500352000 O Spearmint 1.500000 1.000 1.000 

9500353000 O Spearmint, oil 1.500000 0.050 1.000 D281702 

9500358000 O Starfruit 0.010000 1.000 1.000 FHE

9500361000 O Sugar apple 0.010000 1.000 1.000 FHE

9500362000 O Sugarcane, sugar 0.010000 1.000 1.000 FHE

9500362001 O Sugarcane, sugar-babyfood 0.010000 1.000 1.000 FHE

9500363000 O Sugarcane, molasses 0.010000 1.000 1.000 FHE

9500363001 O Sugarcane, molasses-babyfood 0.010000 1.000 1.000 FHE

9500368000 O Tamarind 0.010000 1.000 1.000 FHE

9500372000 O Tea, dried 0.010000 1.000 1.000 FHE

9500373000 O Tea, instant 0.010000 1.000 1.000 FHE

9500373500 O Teff, flour 0.000000 1.000 1.000 

9500390000 O Vinegar 0.010000 1.000 1.000 FHE

9500397000 O Water chestnut 0.000000 1.000 1.000 

9500398000 O Watercress 0.000000 1.000 1.000 
Thiamethoxam (060109) Dietary Exposure and Risk Assessment DP Number D406562 

Page 32 of 32

Attachment 4. Summary of the chronic dietary exposure analysis for thiamethoxam.

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for THIAMETHOXAM NHANES 2003-2008 2-day

Residue file name: C:\Documents and Settings\dmcneill\My 

Documents\Thiamethoxam5\060109 2010 T+FHE+WATER.R08

 Adjustment factor #2 NOT used.

Analysis Date 09-26-2012/09:36:22 Residue file dated: 09-26-2012/08:05:29

Reference dose (RfD, Chronic) = .012 mg/kg bw/day

COMMENT 1: Acute and Chronic RfDs = aPAD and cPAD

===============================================================================

 Total exposure by population subgroup

-------------------------------------------------------------------------------

 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.002663 22.2%

Hispanic 0.002547 21.2%

Non-Hisp-White 0.002754 22.9%

Non-Hisp-Black 0.002134 17.8%

Non-Hisp-Other 0.003014 25.1%

Nursing Infants 0.001493 12.4%

Non-Nursing Infants 0.003037 25.3%

Female 13+ PREG 0.002501 20.8%

Children 1-6 0.004625 38.5%

Children 7-12 0.002599 21.7%

Male 13-19 0.001950 16.3%

Female 13-19/NP 0.002104 17.5%

Male 20+ 0.002315 19.3%

Female 20+/NP 0.002740 22.8%

Seniors 55+ 0.002576 21.5%

All Infants 0.002560 21.3%

Female 13-50 0.002584 21.5%

Children 1-2 0.005286 44.1%

Children 3-5 0.004446 37.1%

Children 6-12 0.002767 23.1%

Youth 13-19 0.002026 16.9%

Adults 20-49 0.002502 20.9%

Adults 50-99 0.002585 21.5%

Female 13-49 0.002585 21.5%

-------------------------------------------------------------------------------