UNITED STATES

                  SECURITIES AND EXCHANGE COMMISSION

                       Washington,  D.C.  20549

                               FORM 10Q

Quarterly Report Pursuant to Section 13 OR 15(d) of the Securities
Exchange Act of 1934

For the quarterly period ended September 30, 2000

Commission File Number: 2-88927

                      FIRST KEYSTONE CORPORATION
        (Exact name of registrant as specified in its charter)


           Pennsylvania                        23-2249083
(State or other jurisdiction of            (I.R.S. Employer
incorporation or organization)            identification No.)


111 West Front Street, Berwick, PA               18603
(Address of principal executive offices)       (Zip Code)


Registrant's telephone number, including area code:  (570) 752-3671

     Indicate by check mark whether the registrant (1) has filed all
reports required to be filed by Section 13 or 15(d) of the Securities
Exchange Act of 1934 during the preceding 12 months (or for such
shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90
days.

                         Yes   X     No


     Indicate the number of shares outstanding of each of the issuer's
classes of common stock, as of the latest practical date:

Common Stock, $2 Par Value, 2,833,727 shares as of September 30, 2000.


<PAGE>


                    PART I. - FINANCIAL INFORMATION

Item. 1  Financial Statements

<TABLE>

                      FIRST KEYSTONE CORPORATION
                            BALANCE SHEETS
                              (Unaudited)

<CAPTION>

(Amounts in thousands, except per share data)

                                                 September     December
                                                    2000          1999
<S>                                          <C>            <C>
ASSETS
Cash and due from banks                             $  5,968       $  6,884
Interest bearing deposits with banks                      47             80
Available-for-sale securities carried
  at estimated fair value                            143,042        123,468
Investment securities, held to maturity
  securities, estimated fair value of
  $8,794 and $11,335                                   8,975         11,563
Loans, net of unearned income                        186,797        185,231
Allowance for loan losses                             (2,576)        (2,600)
                                                    ________       ________
Net loans                                           $184,221       $182,631
                                                    ________       ________
Bank premises and equipment                            3,668          3,881
Other real estate owned                                   13             85
Interest receivable                                    2,440          2,239
Other assets                                           1,814          2,685
                                                    ________       ________
  Total Assets                                      $350,188       $333,516

LIABILITIES AND STOCKHOLDERS' EQUITY
LIABILITIES
Deposits
  Non-interest bearing                              $ 24,538       $ 20,919
  Interest bearing                                   235,265        223,761
                                                    ________       ________
  Total deposits                                    $259,803       $244,680
Short-term borrowings                                 23,359         31,594
Long-term borrowings                                  31,250         26,000
Accrued expenses and other
  liabilities                                          2,360          1,884
                                                    ________       ________
  Total Liabilities                                 $316,772       $304,158

STOCKHOLDERS' EQUITY
Common stock, par value $2 per share                $  5,867       $  5,867
Surplus                                                9,761          9,761
Retained earnings                                     22,514         20,285
Accumulated other comprehensive
  income (loss)                                       (1,630)        (3,459)
Treasury stock at cost 100,000
  shares in 2000 and 100,000 in 1999                  (3,096)        (3,096)
                                                    ________        _______

  Total Stockholders' Equity                        $ 33,416       $ 29,358
                                                    ________       ________
  Total Liabilities and Stockholders'
    Equity                                          $350,188       $333,516

See Accompanying Notes to Financial Statements

</TABLE>

                                   1

<PAGE>


<TABLE>

                      FIRST KEYSTONE CORPORATION
                         STATEMENTS OF INCOME
        FOR THE THREE MONTHS ENDED September 30, 2000 AND 1999
                              (Unaudited)

<CAPTION>

(Amounts in thousands except per share data)

                                                  2000          1999
<S>                                        <C>             <C>
INTEREST INCOME
Interest and fees on loans                        $   4,031       $   3,706
Interest and dividend income on
  securities                                          2,520           2,182
Interest on deposits in banks                     1                      12
                                                  _________       _________
  Total Interest Income                           $   6,552       $   5,900

INTEREST EXPENSE
Interest on deposits                              $   2,786       $   2,356
Interest on short-term borrowings                       384             395
Interest on long-term borrowings                        479             279
                                                  _________       _________
  Total Interest Expense                          $   3,649       $   3,030

Net interest income                               $   2,903       $   2,870
Provision for loan losses                                75              50
                                                  _________       _________
Net Interest Income After
  Provision for Loan Losses                       $   2,828       $   2,820

OTHER INCOME
Service charges on deposit accounts               $     264       $     227
Other non-interest income                               191             157
Investment securities gains (losses)
  net                                                    70              77
                                                  _________       _________
  Total Other Income                              $     525       $     461

OTHER EXPENSES
Salaries and employee benefits                    $     938       $     884
Net occupancy and fixed asset expense                   273             234
Other non-interest expense                              451             470
                                                  _________       _________
  Total Other Expenses                            $   1,662       $   1,588

Income before income taxes                        $   1,691       $   1,693
Applicable income tax (benefit)                         328             338
                                                  _________       _________
Net Income                                        $   1,363       $   1,355

Per Share Data
  Net Income                                      $     .48       $     .47
  Cash dividends                                        .19             .17
  Weighted average shares outstanding             2,833,727       2,872,718

See Accompanying Notes to Financial Statements

</TABLE>

                                   2

<PAGE>


<TABLE>
                      FIRST KEYSTONE CORPORATION
                         STATEMENTS OF INCOME
         FOR THE NINE MONTHS ENDED September 30, 2000 AND 1999
                              (Unaudited)

<CAPTION>

(Amounts in thousands except per share data)

                                                  2000          1999
<S>                                         <C>            <C>
INTEREST INCOME
Interest and fees on loans                         $  11,809      $  10,728
Interest and dividend income on
  securities                                           7,022          6,207
Interest on deposits in banks                              4            165
                                                   _________      _________
  Total Interest Income                            $  18,835      $  17,100

INTEREST EXPENSE
Interest on deposits                               $   8,045      $   7,082
Interest on short-term borrowings                      1,021            989
Interest on long-term borrowings                       1,142            698
                                                   _________      _________
  Total Interest Expense                           $  10,208      $   8,769

Net interest income                                $   8,627      $   8,331
Provision for loan losses                                235            225
                                                   _________      _________
Net Interest Income After
  Provision for Loan Losses                        $   8,392      $   8,106

OTHER INCOME
Service charges on deposit accounts                $     719      $     645
Other non-interest income                                490            485
Investment securities gains (losses)
  net                                                    123            173
                                                   _________      _________
  Total Other Income                               $   1,332      $   1,303

OTHER EXPENSES
Salaries and employee benefits                     $   2,833      $   2,501
Net occupancy and fixed asset expense                    758            717
Other non-interest expense                             1,479          1,378
                                                   _________      _________
  Total Other Expenses                             $   5,070      $   4,596

Income before income taxes                         $   4,654      $   4,813
Applicable income tax (benefit)                          810            935
                                                   _________      _________
Net Income                                         $   3,844      $   3,878

Per Share Data
  Net Income                                       $    1.36      $    1.35
  Cash dividends                                         .57            .51
  Weighted average shares outstanding              2,833,727      2,872,718

See Accompanying Notes to Financial Statements

</TABLE>

                                   3

<PAGE>


<TABLE>

                      FIRST KEYSTONE CORPORATION
                       STATEMENTS OF CASH FLOWS
         FOR THE NINE MONTHS ENDED September 30, 2000 AND 1999
                              (Unaudited)

<CAPTION>

(Amounts in thousands)

                                                  2000          1999
<S>                                          <C>            <C>
OPERATING ACTIVITIES
Net income                                          $  3,844       $  3,878
Adjustments to reconcile net
  income to net cash provided
  by operating activities:
  Provision for loan losses                                                       235       225
  Provision for depreciation
    and amortization                                     302            301
  Premium amortization on
    investment securities                                 76            197
  Discount accretion on
    investment securities                               (647)          (142)
  Gain on sale of mortgage loans                         (19)            (9)
  Proceeds from sale of mortgage
    loans                                              1,812          4,016
  Originations of mortgage loans
    for resale                                        (2,441)        (6,341)
  (Gain) loss on sales of investment
    securities                                          (123)           (77)
  (Gain) loss on sales of other real
    estate owned                                          36              0
  Deferred income tax (benefit)                          (27)           (44)
  (Increase) decrease in interest
    receivable and other assets                         (195)          (452)
  Increase (decrease) in interest
    payable, accrued expenses and
    other liabilities                                    476            251
                                                    ________       ________
  Net Cash Provided by Operating
    Activities                                      $  3,329       $  1,803

INVESTING ACTIVITIES
  Purchases of investment securities
    available-for-sale                              $(54,755)      $(55,358)
  Proceeds from sales of investment
    securities available for sale                     34,718         24,124
  Proceeds from maturities and
    redemptions of investment
    securities available for sale                      3,166         12,942
  Purchase of investment securities
    held-to-maturity                                       0              0
  Proceeds from maturities and
    redemption of investment
    securities held to maturity                        3,314          1,858
  Net (increase) decrease in loans                    (1,273)       (16,781)
  Purchase of premises and equipment                     (89)                    (431)
  Proceeds from sale of other real
    estate owned                                         118              0
                                                    ________       ________
  Net Cash Used by Investing Activities             $(14,801)      $(33,646)

FINANCING ACTIVITIES
  Net increase (decrease) in deposits               $ 15,123       $  2,885
  Net increase (decrease) in
    short-term borrowings                             (8,235)        23,789
  Net increase (decrease) in
    long-term borrowings                               5,250          9,000
  Acquisition of treasury stock                            0         (1,906)
  Cash dividends                                      (1,615)        (1,461)
                                                    ________       ________
  Net Cash Provided by Financing
    Activities                                      $ 10,523       $ 32,307
Increase (Decrease) in Cash
    and Cash Equivalent                                 (949)          $464
Cash and Cash Equivalents, Beginning                   6,964          7,055
                                                    ________       ________
Cash and Cash Equivalents, Ending                   $  6,015       $  7,519

SUPPLEMENTAL DISCLOSURE OF CASH
  FLOW INFORMATION
  Cash paid during period for
    Interest                                        $ 10,029       $  8,707
    Income Taxes                                         695            923


See Accompanying Notes to Financial Statements

</TABLE>

                                   4

<PAGE>



                      FIRST KEYSTONE CORPORATION
              CONSOLIDATED NOTES TO FINANCIAL STATEMENTS
                          September 30, 2000
                              (Unaudited)


Note 1.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

     The accounting policies of First Keystone Corporation and
Subsidiary (the "Corporation") are in accordance with generally
accepted accounting principles and conform to common practices within
the banking industry. The more significant policies follow:

PRINCIPLES OF CONSOLIDATION
     The consolidated financial statements include the accounts of
First Keystone Corporation and its wholly-owned Subsidiary, The First
National Bank of Berwick (the "Bank"). All significant inter-company
balances and transactions have been eliminated in consolidation.

NATURE OF OPERATIONS
     The Corporation, headquartered in Berwick, Pennsylvania, provides
a full range of banking, trust and related services through its wholly
owned Bank subsidiary and is subject to competition from other
financial institutions in connection with these services. The Bank
serves a customer base which includes individuals, businesses, public
and institutional customers primarily located in the Northeast Region
of Pennsylvania. The Bank has nine full service offices and 12 ATMs
located in Columbia, Luzerne and Montour Counties. The Corporation and
its subsidiary must also adhere to certain federal banking laws and
regulations and are subject to periodic examinations made by various
federal agencies.
     The Corporation has a commercial banking operation and trust
department as its major lines of business. The commercial banking
operation includes a commercial services and retail services area and
has historically constituted over 90% of the Corporation's revenue and
profit and is the only reportable segment. Commercial services
includes lending and related financial services to small and medium
sized corporations and other business entities. The retail services
includes sales and distribution (direct lending, deposit gathering,
and retail mortgage lending) primarily to individuals. The trust
department includes investment management, estate planning, employee
benefit administration, and personal trust services which produce fee
based income. The business units are identified by the products or
services offered by the business unit and the channel through which
the product or service is delivered. The accounting policies of the
individual business units are the same as those of the Corporation.

USE OF ESTIMATES
     The preparation of these consolidated financial statements in
conformity with generally accepted accounting principles requires
management to make estimates and assumptions that affect the reported
amounts of assets and liabilities and disclosure of contingent assets
and liabilities at the date of these consolidated financial statements
and the reported amounts of income and expenses during the reporting
periods. Actual results could differ from those estimates.

INVESTMENT SECURITIES
     The Corporation classifies its investment securities as either
"Held-to-Maturity" or "Available-for-Sale" at the time of purchase.
Debt securities are classified as held-to-maturity when the
Corporation has the ability and positive intent to hold the securities
to maturity. Investment securities Held-to-Maturity are carried at
cost adjusted for amortization of premium and accretion of discount to
maturity.
     Debt securities not classified as Held-to-Maturity and equity
securities are included in the Available-for-Sale category and are
carried at fair value. The amount of any unrealized gain or loss, net
of the effect of deferred income taxes, is reported as other
comprehensive income as a component of Stockholders' Equity.
Management's

                                   5

<PAGE>


decision to sell available-for-sale securities is based on changes in
economic conditions controlling the sources and applications of funds,
terms, availability of and yield of alternative investments, interest
rate risk and the need for liquidity.
     The cost of debt securities classified as Held-to-Maturity or
Available-for-Sale is adjusted for amortization of premiums and
accretion of discounts to maturity. Such amortization and accretion,
as well as interest and dividends is included in interest income from
investments. Realized gains and losses are included in net investment
securities gains. The cost of investment securities sold, redeemed or
matured is based on the specific identification method.

LOANS
     Loans are stated at their outstanding unpaid principal balances,
net of deferred fees or costs, unearned income and the allowance for
loan losses. Interest on installment loans is recognized as income
over the term of each loan, generally, by the "actuarial method".
Interest on all other loans is primarily recognized based upon the
principal amount outstanding. Loan origination fees and certain direct
loan origination costs have been deferred with the net amount
amortized using the interest method over the contractual life of the
related loans as an interest yield adjustment.
     Mortgage loans held for resale are carried at the lower of cost
or market on an aggregate basis. These loans are sold without recourse
to the Corporation.

Non-Accrual Loans - Generally, a loan is classified as non-accrual and
the accrual of interest on such a loan is discontinued when the
contractual payment of principal or interest has become 90 days past
due or management has serious doubts about further collectibility of
principal or interest, even though the loan currently is performing. A
loan may remain on accrual status if it is in the process of
collection and is either guaranteed or well secured. When a loan is
placed on non-accrual status, unpaid interest credited to income in
the current year is reversed and unpaid interest accrued in prior
years is charged against the allowance for loan losses.
Certain non-accrual loans may continue to perform, that is, payments are still
being received. Generally, the payments are applied to principal.
These loans remain under constant scrutiny and if performance
continues, interest income may be recorded on a cash basis based on
management's judgement as to collectibility of principal.

Allowance for Loan Losses - The allowance for loan losses is
established through provisions for loan losses charged against income.
Loans deemed to be uncollectible are charged against the allowance for
loan losses and subsequent recoveries, if any, are credited to the
allowance.
     A principal factor in estimating the allowance for loan losses is
the measurement of impaired loans. A loan is considered impaired when,
based on current information and events, it is probable that the
Corporation will be unable to collect all amounts due according to the
contractual terms of the loan agreement. Under current accounting
standards, the allowance for loan losses related to impaired loans is
based on discounted cash flows using the effective interest rate of
the loan or the fair value of the collateral for certain collateral
dependent loans.
     The allowance for loan losses is maintained at a level estimated
by management to be adequate to absorb potential loan losses.
Management's periodic evaluation of the adequacy of the allowance for
loan losses is based on the Corporation's past loan loss experience,
known and inherent risks in the portfolio, adverse situations that may
affect the borrower's ability to repay (including the timing of future
payments), the estimated value of any underlying collateral,
composition of the loan portfolio, current economic conditions, and
other relevant factors. This evaluation is inherently subjective as it
requires material estimates including the amounts and timing of future
cash flows expected to be received on impaired loans that may be
susceptible to significant change.

PREMISES AND EQUIPMENT
     Premises and equipment are stated at cost less accumulated
depreciation computed principally on the straight-line method over the
estimated useful lives of the assets. Maintenance and minor repairs
are charged to operations as incurred. The cost and accumulated
depreciation of the premises and equipment retired or sold are
eliminated from the property accounts at the time of retirement or
sale, and the resulting gain or loss is reflected in current
operations.

                                   6

<PAGE>


MORTGAGE SERVICING RIGHTS
     The Corporation originates and sells real estate loans to
investors in the secondary mortgage market. After the sale, the
Corporation retains the right to service certain loans. When
originated mortgage loans are sold and servicing is retained, a
servicing asset is capitalized based on relative fair value at the
date of sale. Servicing assets are amortized as an offset to other
fees in proportion to, and over the period of, estimated net servicing
income. The unamortized cost is included in other assets in the
accompanying consolidated balance sheet. The servicing rights are
periodically evaluated for impairment based on their relative fair
value.

OTHER REAL ESTATE OWNED
     Real estate properties acquired through, or in lieu of, loan
foreclosure are held for sale and are initially recorded at fair value
on the date of foreclosure establishing a new cost basis. After
foreclosure, valuations are periodically performed by management and
the real estate is carried at the lower of carrying amount or fair
value less cost to sell. Revenues derived from and costs to maintain
the assets and subsequent gains and losses on sales are included in
other non-interest income and expense.

INCOME TAXES
     The provision for income taxes is based on the results of
operations, adjusted primarily for tax-exempt income. Certain items of
income and expense are reported in different periods for financial
reporting and tax return purposes. Deferred tax assets and liabilities
are determined based on the differences between the consolidated
financial statement and income tax bases of assets and liabilities
measured by using the enacted tax rates and laws expected to be in
effect when the timing differences are expected to reverse. Deferred
tax expense or benefit is based on the difference between deferred tax
asset or liability from period to period.

PER SHARE DATA
     Statement of Financial Accounting Standards (SFAS) No. 128,
Earnings Per Share, requires dual presentation of basic and fully
diluted earnings per share. Basic earnings per share is calculated by
dividing net income by the weighted average number of shares of common
stock outstanding at the end of each period. Fully diluted earnings
per share is calculated by increasing the denominator for the assumed
conversion of all potentially dilutive securities. The Corporation's
dilutive securities are limited to stock options which currently have
no effect on earnings per share since the market price per share
historically has not been greater than the lowest stock option
exercise price.
     Per share data has been adjusted retroactively for stock splits
and stock dividends.

CASH FLOW INFORMATION
     For purposes of reporting consolidated cash flows, cash and cash
equivalents include cash on hand and due from other banks and interest
bearing deposits in other banks. The Corporation considers cash
classified as interest bearing deposits with other banks as a cash
equivalent since they are represented by cash accounts essentially on
a demand basis.

TRUST ASSETS AND INCOME
     Property held by the Corporation in a fiduciary or agency
capacity for its customers is not included in the accompanying
consolidated financial statements since such items are not assets of
the Corporation. Trust Department income is recognized on a cash basis
and is not materially different than if it were reported on an accrual
basis.

NEW ACCOUNTING STANDARDS
     Statement of Financial Accounting Standards (SFAS) No. 133 (as
amended by SFAS No. 137), "Accounting for Derivative Instruments and
Hedging Activities", becomes effective for financial reporting periods
beginning after June 15, 2000. SFAS 133 requires fair value accounting
for all stand-alone derivatives and many derivatives embedded in other
instruments and contracts. Since the Corporation does not enter into
transactions involving derivatives described in the standard and does
not engage in hedging activities, the standard is not expected to have
a significant impact on the Corporation's consolidated financial
condition or results of operations.

                                   7

<PAGE>


Note 2.  ALLOWANCE FOR LOAN LOSSES

     Changes in the allowance for loan losses for the periods ended
September 30, 2000, and September 30, 1999, were as follows:

<TABLE>
<CAPTION>

(amounts in thousands)
                                               2000          1999
<S>                                        <C>           <C>
Balance, January 1                               $2,600        $2,421
Provision charged to operations                     235           225
Loans charged off                                  (274)         (154)
Recoveries                                           15            80
                                                               ______   ______
Balance, September 30                            $2,576        $2,572

</TABLE>

     At September 30, 2000, the recorded investment in loans that are
considered to be impaired as defined by SFAS No. 114 was $71,935. No
additional charge to operations was required to provide for the
impaired loans since the total allowance for loan losses is estimated
by management to be adequate to provide for the loan loss allowance
required by SFAS No. 114 along with any other potential losses.
     At September 30, 2000, there were no significant commitments to
lend additional funds with respect to non-accrual and restructured
loans.


Note 3.  SHORT-TERM BORROWINGS

     Federal funds purchased, securities sold under agreements to
repurchase and Federal Home Loan Bank advances generally represent
overnight or less than 30-day borrowings. U.S. Treasury tax and loan
notes for collections made by the Bank are payable on demand.


Note 4.  LONG-TERM BORROWINGS

     Long-term borrowings are comprised of advances from the Federal
Home Loan Bank (FHLB). Under terms of a blanket agreement, collateral
for the loans are secured by certain qualifying assets of the
Corporation's banking subsidiary which consist principally of first
mortgage loans.


Note 5.  FINANCIAL INSTRUMENTS WITH OFF-BALANCE SHEET RISK AND
         CONCENTRATIONS OF CREDIT RISK

The Corporation is a party to financial instruments with off-balance sheet
         risk in the normal course of business to meet the
financing needs of its customers. These financial instruments include
commitments to extend credit and standby letters of credit. Those
instruments involve, to varying degrees, elements of credit and
interest rate risk in excess of the amount recognized in the
consolidated balance sheets. The contract or notional amounts of those
instruments reflect the extent of involvement the Corporation has in
particular classes of financial instruments. The Corporation does not
engage in trading activities with respect to any of its financial
instruments with off-balance sheet risk.
     The Corporation's exposure to credit loss in the event of
nonperformance by the other party to the financial instrument for
commitments to extend credit and standby letters of credit is
represented by the contractual notional amount of those instruments.
     The Corporation uses the same credit policies in making
commitments and conditional obligations as it does for on-balance
sheet instruments.

                                   8

<PAGE>


     The Corporation may require collateral or other security to
support financial instruments with off-balance sheet credit risk. The
contract or notional amounts at September 30, 2000, and December 31,
1999, were as follows:

<TABLE>
<CAPTION>

(amounts in thousands)                      September 30,     December 31,
                                               2000              1999
<S>                                        <C>             <C>
Financial instruments whose
  contract amounts represent
  credit risk:
  Commitments to extend credit                     $14,748        $17,348
  Standby letters of credit                        $   993        $   633

</TABLE>


     Commitments to extend credit are agreements to lend to a customer
as long as there is no violation of any condition established in the
contract. Commitments generally have fixed expiration dates or other
termination clauses that may require payment of a fee. Since many of
the commitments are expected to expire without being drawn upon, the
total commitment amounts do not necessarily represent future cash
requirements. The Corporation evaluates each customer's
creditworthiness on a case-by-case basis. The amount of collateral
obtained, if deemed necessary by the Corporation upon extension of
credit, is based on management's credit evaluation of the counter-party.
        Collateral held varies but may include accounts receivable,
inventory, property, plant and equipment, and income-producing
commercial properties.
     Standby letters of credit are conditional commitments issued by
the Corporation to guarantee the performance of a customer to a third
party. The credit risk involved in issuing letters of credit is
essentially the same as that involved in extending loan facilities to
customers. The Corporation may hold collateral to support standby
letters of credit for which collateral is deemed necessary.
   The Corporation grants commercial, agribusiness and residential
loans to customers within the state. It is management's opinion that
the loan portfolio was balanced and diversified at September 30, 2000,
to the extent necessary to avoid any significant concentration of
credit risk.


Note 6.  STOCKHOLDERS' EQUITY

     Changes in Stockholders' Equity for the period ended September
30, 2000, were are follows:


<TABLE>
<CAPTION>

(Amounts in thousands, except common share data)

                                         Common          Common
                                         Shares         Stock        Surplus
                                         ______          ______      _______

<S>                                  <C>              <C>          <C>

Balance at January 1, 2000                2,933,727        $5,867       $9,761

Comprehensive Income:
  Net Income
    Change in unrealized
    gain (loss) on
    investment securities
    available-for-sale,
    net of reclassification
    adjustment and tax
    effects
  Total Comprehensive
    income (loss)
Cash dividends -
  $.57 per share
                                          _________        ______       ______
Balance at September 30, 2000             2,933,727        $5,867       $9,761


<CAPTION>
(Amounts in thousands, except common share data)

                                     Compre-                       Other
                                     hensive       Retained   Comprehensive
                                     Income         Earnings      Income
                                    ________       ________   _____________

<S>                                <C>          <C>           <C>

Balance at January 1, 2000                           $20,285       $(3,459)

Comprehensive Income:
  Net Income                            3,844          3,844
    Change in unrealized
    gain (loss) on
    investment securities
    available-for-sale,
    net of reclassification
    adjustment and tax
    effects                             1,829                        1,829
                                        _____
  Total Comprehensive
    income (loss)                       5,673
Cash dividends -
   $.57 per share                                     (1,615)
                                                     _______       _______
Balance at September 30, 2000                        $22,514       $(1,630)


<CAPTION>
(Amounts in thousands, except common share data)

                                                Treasury
                                                  Stock         Total
                                                 ______         _____

<S>                                          <C>            <C>
Balance at January 1, 2000                        $(3,096)       $29,358

Comprehensive Income:
  Net Income                                                       3,844
    Change in unrealized
    gain (loss) on
    investment securities
    available-for-sale,
    net of reclassification
    adjustment and tax
    effects                                                        1,829
  Total Comprehensive
    income (loss)
Cash dividends -
  $.57 per share                                                  (1,615)
                                                  _______        _______
Balance at September 30, 2000                     $(3,096)       $33,416


</TABLE>


                                 9


<PAGE>


Note 7.  MANAGEMENT'S ASSERTIONS AND COMMENTS REQUIRED TO BE
         PROVIDED WITH FORM 10Q FILING

     In management's opinion, the consolidated interim financial
statements reflect fair presentation of the consolidated financial
position of First Keystone Corporation and Subsidiary, and the results
of their operations and their cash flows for the interim periods
presented.  Further, the consolidated interim financial statements
reflect all adjustments, which are in the opinion of management,
necessary to present fairly the consolidated financial condition and
consolidated results of operations and cash flows for the interim
period presented and that all such adjustments to the consolidated
financial statements are of a normal recurring nature.

     The results of operations for the nine-month period ended
September 30, 2000, are not necessarily indicative of the results to
be expected for the full year.

     These consolidated interim financial statements have been
prepared in accordance with requirements of Form 10Q and therefore do
not include all disclosures normally required by generally accepted
accounting principles applicable to financial institutions as included
with consolidated financial statements included in the Corporation's
annual Form 10K filing.  The reader of these consolidated interim
financial statements may wish to refer to the Corporation's annual
report or Form 10K for the period ended December 31, 1999, filed with
the Securities and Exchange Commission.


Note 8.  AMENDMENT OF RULE 10-01 OF REGULATION S-X REQUIRING
         REVIEWED QUARTERLY FINANCIAL STATEMENTS

     In accordance with the new amendment effective for the period
ended March 31, 2000, the accompanying consolidated financial
statements have been reviewed by Independent Certified Public
Accountants whose report is being submitted as an integral part of
this Form 10Q filing.


                                   10


<PAGE>


REPORT OF INDEPENDENT CERTIFIED PUBLIC ACCOUNTS

Board of Directors and Stockholders of First Keystone Corporation:


We have reviewed the accompanying consolidated balance sheet of First
Keystone Corporation and Subsidiary as of September 30, 2000, and the
related consolidated statements of income and cash flows for the three
and nine-month periods then ended.  These consolidated financial
statements are the responsibility of the management of First Keystone
Corporation and Subsidiary.

We conducted our review in accordance with standards established by
the American Institute of Certified Public Accountants.  A review of
interim financial information consists principally of applying
analytical procedures to financial data and making inquiries of
persons responsible for financial and accounting matters.  It is
substantially less in scope than an audit conducted in accordance with
generally accepted auditing standards, the objective of which is the
expression of an opinion regarding the financial statements taken as a
whole.  Accordingly, we do not express such an opinion.

Based on our review, we are not aware of any material modifications
that should be made to the September 30, 2000, financial statements
for them to be in conformity with generally accepted accounting
principles.

The accompanying balance sheet of First Keystone Corporation and
Subsidiary for the year ended December 31, 1999, was audited by us as
part of our audit of the financial statements for the year ended
December 31, 1999, taken as a whole and we expressed an unqualified
opinion on them in our report dated January 10, 2000, but we have not
performed any auditing procedures since that date.

The accompanying statements of income and cash flows of First Keystone
Corporation and Subsidiary for the three and nine-month periods ended
September 30, 1999, were not audited by us and, accordingly, we do not
express an opinion on them.





/s/ J. H. Williams & Co., LLP
J. H. Williams & Co., LLP




Kingston, Pennsylvania
October 26, 2000


                                   11


<PAGE>


Item 2.  First Keystone Corporation Management's Discussion
         and Analysis of Financial Condition and
         Results of Operation as of September 30, 2000




RESULTS OF OPERATIONS

     First Keystone Corporation realized earnings for the third
quarter of 2000 of $1,363,000, an increase of $8,000, or 0.6% over the
third quarter of 1999.  Nine months net income for the period ended
September 30, 2000, amounted to $3,844,000, a decrease of 0.9% over
the $3,878,000 net income reported September 30, 1999.  On a per share
basis net income per share increased to $1.36 for the nine months of
2000 compared to $1.35 for the first nine months of 1999, while
dividends increased to $.57 per share up from $.51 in 1999, an
increase of 11.8%.

     Year-to-date net income annualized amounts to a return on average
common equity of 1.51% and a return on assets of 16.76%.  For the nine
months ended September 30, 1999, these measures were 1.59% and 15.79%,
respectively on an annualized basis.


NET INTEREST INCOME

     The major source of operating income for the Corporation is net
interest income, defined as interest income less interest expense.  In
the third quarter of 2000, interest income amounted to $6,552,000, an
increase of $652,000 or 11.1% over the third quarter of 1999.
Interest expense amounted to $3,649,000 in the third quarter of 2000,
an increase of $619,000, or 20.4% over the third quarter of 1999.
Accordingly, net interest income amounted to $2,903,000 in the third
quarter of 2000, an increase of $33,000, or 1.1% over the third
quarter of 1999.  Year-to-date for the nine months ended September 30,
2000, total interest income increased $1,735,000, or 10.1% over the
first nine months of 1999.  Total interest expense increased
$1,439,000, or 16.4% for the first nine months of 2000 over 1999.
This resulted in net interest income increasing $296,000, or 3.6% for
the nine months ended September 30, 2000, over 1999.

     Our net interest margin for the quarter ended September 30, 2000,
was 3.94% compared to 3.91% for the quarter ended September 30, 1999.
For the nine months ended September 30, 2000, our net interest margin
was 4.10% compared to 3.98% for the first nine months of 1999.


PROVISION FOR LOAN LOSSES

     The provision for loan losses for the quarter ended September 30,
2000, was $75,000 compared to $50,000 for the third quarter of 1999.
Year-to-date, the provision for loan losses amounts to $235,000 in
2000 as compared to the $225,000 provision for the period ended
September 30, 1999.  The provision for possible loan losses increased
in 2000.  Our allowance for loan losses of $2,576,000 as of September
30, 2000, is down slightly compared to our allowance for loan losses
of $2,600,000 as of December 31, 1999.  Net charge-offs totaled
$259,000 for the nine months ended September 30, 2000, as compared to
$74,000 for the first nine months of 1999.

     The allowance for loan losses as a percentage of loans, net of
unearned interest was 1.38% as of September 30, 2000, and 1.40% as of
December 30, 1999.


                                   12


<PAGE>


NON-INTEREST INCOME

     Total non-interest or other income was $525,000 for the quarter
ended September 30, 2000, as compared to $461,000 for the quarter
ended September 30, 1999.  Excluding investment security gains and
losses, non-interest income was $455,000 for the third quarter of
2000, an increase of $71,000 over the third quarter of 1999.  For the
nine months ended September 30, 2000, total non-interest income was
$1,332,000, an increase of $29,000, or 2.2% over the first nine months
of 1999.  An increase in service charges on deposit accounts, was the
primary reason for the gain in non-interest income year-to-date in
2000.


NON-INTEREST EXPENSES

     Total non-interest, or other expenses, was $1,662,000 for the
quarter ended September 30, 2000, as compared to $1,588,000 for the
quarter ended September 30, 1999.  The increase of $74,000 is
comprised of salary and benefits increasing $54,000, occupancy expense
increasing $39,000, and other non-interest expense decreasing $19,000.

     For the nine months ended September 30, 2000, total non-interest
expense was $5,070,000, an increase of $474,000, or 10.3% over the
first nine months of 1999.  Expenses associated with employee expense
and benefits continues to be the largest category of non-interest
expenses.  Salaries and benefits amount to 55.9% of total non-interest
expense for the nine months ended September 30, 2000, as compared to
54.4% for the first nine months of 1999.  Salaries and benefits
amounted to $2,833,000 for the nine months ended September 30, 2000,
an increase of $332,000, or 13.3% over the first nine months of 1999.
The increase was a result of normal salary adjustments, higher
employee benefit costs and an increased number of employees.  Net
occupancy expense amounted to $758,000 for the nine months ended
September 30, 2000, an increase of $41,000, or 5.7% over 1999.  Other
non-interest expenses amounted to $1,479,000 for the nine months ended
September 30, 2000, an increase of $101,000, or 7.3% over the first
nine months of 1999.  Our overall non-interest expense of less than 2%
of average assets on an annualized basis for 2000 and 1999, places us
among the leaders of our peer financial institutions at controlling
total non-interest expense.


INCOME TAXES

     Effective tax planning has helped produce favorable net income.
The effective total income tax rate was 19.4% for the third quarter of
2000 as compared to 20.0% for the third quarter of 1999.  For the nine
months ended September 30, 2000, our tax liability amounted to
$810,000, a decrease of $125,000 over 1999.  Our effective tax rate of
17.4% as of September 30, 2000, compared to an effective tax rate of
19.4% for the first nine months of 1999.


ANALYSIS OF FINANCIAL CONDITION

ASSETS

     Total assets increased to $350,188,000 as of September 30, 2000,
an increase of $16,672,000, or 5.0% over year-end 1999.  Total
deposits increased to $259,803,000 as of September 30, 2000, an
increase of $15,123,000, or 6.2% over year-end 1999.

     The Corporation was able to reduce borrowed funds with the
increase in total deposits.  Short-term borrowings decreased to
$23,359,000, a decrease of $8,235,000 over December 31, 1999.
 Long-term borrowings increased in to $31,250,000 as of September 30, 2000,
up from $26,000,000 at year-end 1999.  Accordingly, total borrowings
amounted to $54,609,000 as of September 30, 2000, as compared to
$57,594,000 as of December 31, 1999, a decrease of $2,985,000.


                                   13


<PAGE>


EARNING ASSETS

     Our primary earning asset, loans, net of unearned income
increased to $186,797,000 as of September 30, 1999, up $1,566,000, or
0.8% since year-end 1999.  The loan portfolio is well diversified and
increases in the portfolio have been primarily from increased
originations of residential real estate loans and commercial real
estate loans.

     In addition to loans, our investment portfolio, another earning
asset, increased in size from December 31, 1999, to September 30,
2000.  Held-to-maturity securities amounted to $8,975,000 as of
September 30, 2000, a decrease of $2,588,000 since year-end 1999.
However, available-for-sale securities increased to $143,042,000 as of
September 30, 2000, an increase of $19,574,000, or 15.9% from year-end
1999.  Interest bearing deposits with banks amounted to $47,000 on
September 30, 2000, as compared to $80,000 as of December 31, 1999.


ALLOWANCE FOR LOAN LOSSES

     Management performs a quarterly analysis to determine the
adequacy of the allowance for loan losses.  The methodology in
determining adequacy incorporates specific and general allocations
together with a risk/loss analysis on various segments of the
portfolio according to an internal loan review process.  Management
maintains its loan review and loan classification standards consistent
with those of its regulatory supervisory authority.  Management feels,
considering the conservative portfolio composition, which is largely
composed of small retail loans (mortgages and installments) with
minimal classified assets, low delinquencies, and favorable loss
history, that the allowance for loan loss is adequate to cover
foreseeable future losses.

     Any loans classified for regulatory purposes as loss, doubtful,
substandard, or special mention that have not been disclosed under
Industry Guide 3 do not (i) represent or result from trends or
uncertainties which management reasonably expects will materially
impact future operating results, liquidity, or capital resources, or
(ii) represent material credits about which management is aware of any
information which causes management to have serious doubts as to the
ability of such borrowers to comply with the loan repayment terms.

     The company was required to adopt Financial Accounting Standards
Board Statement No. 114, "Accounting by Creditors for Impairment of a
Loan" - Refer to Note 5 above for details.


NON-PERFORMING ASSETS

     Non-performing assets consist of non-accrual and restructured
loans, other real estate and foreclosed assets, together with the
loans past-due 90 days or more and still accruing.  As of September
30, 2000, total non-performing assets were $1,142 as compared to
$750,000 on December 31, 1999.  Non-performing assets to total loans
and foreclosed assets was .61% as of September 30, 2000, and .40% as
of December 31, 1999.

     Interest income received on non-performing loans as of September
30, 2000, was $19,904 compared to $6,380 as of December 31, 1999.
Interest income, which would have been recorded on these loans under
the original terms as of September 30, 2000, and December 31, 1999,
was $65,306 and $68,569, respectively.  As of September 30, 2000 and
December 31, 1999, there was no outstanding commitments to advance
additional funds with respect to these non-performing loans.

                                   14


<PAGE>


DEPOSITS AND OTHER BORROWED FUNDS

     As indicated previously, deposit growth amounted to $15,123,000
as total deposits increased to $259,803,000 as of September 30, 2000,
up from $244,680,000 as of year-end 1999.  During 2000, the
Corporation has experienced deposit growth in both non-interest
bearing deposits and interest bearing deposits.  Total short-term and
long-term borrowings decreased by $2,985,000 from year-end 1999.


CAPITAL STRENGTH

     Normal increases in capital are generated by net income, less
cash dividends paid out.  Also, net unrealized losses on investment
securities available-for-sale decreased shareholders' equity, or
capital by $1,630,000 as of September 30, 2000, and $3,459,000 as of
December 31, 1999.  Our stock repurchase plan had repurchased 100,000
shares as of September 30, 2000 and December 31, 1999.  This had an
effect of our reducing our total stockholders' equity by $3,096,000.

     Total stockholders' equity was $33,416,000 as of September 30,
2000, and $29,358,000 as of
December 31, 2000.

     Leverage ratio and risk based capital ratios remain very strong.
As of September 30, 2000, our leverage ratio was 10.09% compared to
10.02% as of December 31, 1999.  In addition, Tier I risk based
capital and total risk based capital ratio as of September 30, 2000,
were 16.53% and 17.82%, respectively.  The same ratios as of December
31, 1999, were 16.43% and 17.85%, respectively.


LIQUIDITY

     The liquidity position of the Corporation remains adequate to
meet customer loan demand and deposit fluctuation.  Managing liquidity
remains an important segment of asset liability management.  Our
overall liquidity position is maintained by an active asset liability
management committee.

     Management feels its current liquidity position is satisfactorily
given a very stable core deposit base which has increased annually.
Secondly, our loan payments and principal paydowns on our mortgage
backed securities provide a steady source of funds.  Also, short-term
investments and maturing investment securities represent additional
sources of liquidity.  Finally, short-term borrowings are readily
accessible at the Federal Reserve Bank discount window, Atlantic
Central Bankers Bank, or the Federal Home Loan Bank.


YEAR 2000 COMPLIANCE

     During 1999, management completed the process of preparing its
computer systems and applications for the Year 2000. The process
involves identifying and remediating date recognition problems in
computer systems and software and other operating equipment that could
be caused by the date change from December 31, 1999, to January 1,
2000. In addition, the process involved working with third parties to
address their year 2000 issues and developing contingency plans to
address potential risks in the event of Year 2000 failures. To date,
First Keystone Corporation has successfully managed the transition
into the Year 2000.

     Unanticipated problems associated with non-compliance by third
parties and disruptions to the economy in general resulting from Year
2000 issues could still have a negative impact on First Keystone
Corporation.  Management will continue to monitor all business
processes, including interaction with customers, vendors, and other
third parties throughout 2000 to address any issues and insure all
processes and systems continue to function properly.


                                   15


<PAGE>


     Through 1999, the Corporation estimates that its total Year 2000
project cost did not exceed $100,000. The expenses for maintenance or
modification of software associated with the Year 2000 were expensed
as incurred. The costs of new software were capitalized and amortized
over the software's useful life. The aforementioned Year 2000 project
cost may change as the Corporation progresses through 2000. Some
additional project costs are expected to be incurred in 2000 for
ongoing monitoring and support activities. These costs will be
expensed as incurred and are estimated not to exceed $25,000.

     Management believes it has an effective plan in place to address
the Year 2000 issues in a timely manner and, thus far, activities have
tracked in accordance with the original plan.


                                   16


<PAGE>


                      PART II - OTHER INFORMATION

     Item 1.     Legal Proceedings

                 None.


     Item 2.     Changes in Securities

                 None.


     Item 3.     Defaults Upon Senior Securities

                 None.


     Item 4.     Submission of Matters to a Vote of Security Holders

                 Annual Meeting of Shareholders of First Keystone
                 Corporation held on Tuesday, April 18, 2000,
                 at 10:00 a.m.


<TABLE>
<CAPTION>

                                                     Votes      Votes
Directors Elected                  Votes For        Against      Withheld
_________________                  _________       ______       _______
<S>                            <C>              <C>             <C>
Budd L. Beyer                  2,404,890        4,268           0
Frederick E. Crispin, Jr.      2,404,890        4,268           0
Jerome F. Fabian               2,406,188        2,970           0
Robert J. Wise                 2,405,140        4,018           0


<CAPTION>
                                                Broker
Directors Elected              Abstentions      Non-Votes
_________________              ___________      _________
<S>                            <C>              <C>
Budd L. Beyer                  0                0
Frederick E. Crispin, Jr.      0                0
Jerome F. Fabian               0                0
Robert J. Wise                 0                0

</TABLE>

Directors Continuing:

John L. Coates, term expires in 2002
Dudley P. Cooley, term expires in 2002
Stanley E. Oberrender, term expires in 2002
John E. Arndt, term expires in 2001
J. Gerald Bazewicz, term expires in 2001
Robert E. Bull, term expires in 2001


Matters Voted Upon:

Selection of J. H. Williams & Co. LLP, as auditors for the
Corporation.

Votes For -  2,406,872
Votes Against -  1,204
Votes Withheld -  0
Abstentions -  1,082
Broker Non-Votes -  0


     Item 5.     Other Information

           None.


                                   17


<PAGE>


     Item 6.     Exhibits and Reports on Form 8-K

                 (a)  Exhibits required by Item 601 Regulation S-K


Exhibit Number                  Description of Exhibit

    3(i)               Articles of Incorporation, as amended
                       (Incorporated by reference to Exhibit 3(i) to
                       Registrant's Form 10Q for the Quarter Ended
                       June 30, 1998 and Exhibit 3(i) to Registrant's
                       Annual Report on Form 10-KSB for the year ended
                       December 31, 1996.)

    3(ii)              Bylaws, as amended (Incorporated by reference
                       to Exhibit 3(ii) to Registrant's Annual Report
                       on Form 10-KSB for the year ended
                       December 31, 1996.)

    10                 Material Contracts (Incorporated by reference
                       to Exhibit 10 to Registrant's Form 10Q for the
                       quarter ended June 30, 1997)

    11                 Statement RE:  Computation of Earnings Per
                                      Share.

    27                        Financial Data Schedule.


                 (b)  The Registrant has filed no reports on Form
                      8-K for this quarter.


                                   18


<PAGE>


                      FIRST KEYSTONE CORPORATION

                              SIGNATURES


     Pursuant to the requirements of the Securities Exchange Act of
1934, the Registrant has duly cause this report to be signed on its
behalf by the undersigned, thereunto duly authorized.


                              FIRST KEYSTONE CORPORATION
                              Registrant


November 8, 2000              /s/ J. Gerald Bazewicz
                              J. Gerald Bazewicz
                              President and
                              Chief Executive Officer
                              (Principal Executive Officer)



November 8, 2000              /s/ David R. Saracino
                              David R. Saracino
                              Treasurer/Assistant Secretary
                              (Principal Accounting Officer)


                                   19


<PAGE>


                           INDEX TO EXHIBITS

Exhibit             Description

  10                Material Contracts
                       Profit Sharing Plan Summary (Incorporated by
                       reference to Exhibit 10 (Page 16) to
                       Registrant's Form 10Q for the quarter
                       ended June 30, 1997) Deferred Compensation
                       (Incorporated by reference to Exhibit 10
                       (Page 17) to Registrant's Form 10Q
                       for the quarter ended June 30, 1997)
                         Other Executive Benefits (Incorporated by
                         reference to Exhibit 99 (Page 9) of
                         the Corporation's Annual Report on
                         Form 10-KSB for the year ended December
                         31, 1996)
                       Management Incentive Compensation Plan
                       (Incorporated by reference to Exhibit 10
                       (Page 18) to Registrant's Form 10Q for
                       the quarter ended June 30, 1997)


  11                Computation of Earnings Per Share

  27                Financial Data Schedule


                                   20


<PAGE>