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SECURITIES AND EXCHANGE COMMISSIONWASHINGTON, DC 20549

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FORM 10-Q

(Mark One)

|  |                                                                                          
|- | -----------------------------------------------------------------------------------------
|x | QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934 
|  |                                                                                          
|  | For the quarterly period ended March 31, 2003                                            
|  |                                                                                          
|  | OR                                                                                       
|  |                                                                                          
|o | TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT OF 1934
|  |                                                                                          
|  | For the transition period from ______ to _______                                         

Commission File Number 0-12950

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ALLIANCE PHARMACEUTICAL CORP.(Exact name of Registrant as specified in its charter)

|                                                               |  |                                        
|-------------------------------------------------------------- |  | ---------------------------------------
|New York                                                       |  | 14-1644018                             
|                                                               |  |                                        
|(State or other jurisdiction of incorporation or organization) |  | (I.R.S. Employer Identification Number)
|                                                               |  |                                        
|6175 Lusk Boulevard San Diego, California                      |  | 92121                                  
|                                                               |  |                                        
|(Address of principal executive offices)                       |  | Zip Code                               
|                                                               |  |                                        

Registrants telephone number, including area code:  858/410-5200

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Indicate by a check whether the registrant (1) has filed all reports required to be filed by section 13 or 15 (d) of the Securities Exchange Act of 1934 during the
preceding 12 months (or for such shorter period that the Registrant was required to file such reports), and (2) has been subject to filing requirements for the past 90 days.

YesxNoo

Indicate by a check mark if the Registrant is an accelerated filer (as defined in Exchange Act Rule 12b-2).

YesoNox

As of May 12, 2003, Registrant had 20,923,961
shares of its Common Stock, $.01 par value, outstanding.

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ALLIANCE PHARMACEUTICAL CORP.

|                                                                                                |                                                      |         
|----------------------------------------------------------------------------------------------- | ---------------------------------------------------- | --------
|INDEX                                                                                           |                                                     
|                                                                                                |                                                      | Page No.
|PART I -
FINANCIAL INFORMATION                                                                  |                                                     
|                                                                                                |                                                     
|Item 1.  
Financial Statements                                                                  |                                                     
|                                                                                                |                                                      |         
|                                                                                                | Condensed Consolidated Balance Sheets                | 3       
|                                                                                                |                                                      |         
|                                                                                                | Condensed Consolidated Statements of Operations      | 4       
|                                                                                                |                                                      |         
|                                                                                                | Condensed Consolidated Statements of Cash Flows      | 5       
|                                                                                                |                                                      |         
|                                                                                                | Notes to Condensed Consolidated Financial Statements | 6       
|                                                                                                |                                                     
|Item 2.  
Managements Discussion and Analysis of Financial Condition and Results of Operations | 10                                                  
|                                                                                                |                                                      |         
|Item 3.  
Quantitative and Qualitative Disclosures About Market Risk                            | 17                                                  
|                                                                                                |                                                     
|Item 4.  
Controls And Procedures                                                               | 17                                                  
|                                                                                                |                                                     
|PART II -
OTHER INFORMATION                                                                     |                                                     
|                                                                                                |                                                     
|Item 6.  
Exhibits and Reports on Form 8-K                                                      | 18                                                  

2



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Part I     
Financial Information:

Item 1.     
Financial Statements

ALLIANCE PHARMACEUTICAL CORP.CONDENSED CONSOLIDATED BALANCE SHEETS

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|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |              |            |  
|---------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ------------------------------------ | --------------- | ----------- | - | ------------- | ------------ | ---------- | -
|                                               |                                                                                                                                                                                                |                                      | March 31,  2003 |             |   | June 30, 2002 |             
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                |                                      | (Unaudited)     |             |   | (Note)        |             
|Assets                                         |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|Current assets:                                |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               | Cash and cash equivalents                                                                                                                                                                      | $                                    | 274,000         |             |   | $             | 1,416,000    |           
|                                               | Other current assets                                                                                                                                                                           |                                      | 32,000          |             |   |               | 804,000      |           
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                | Total current assets                 |                 | 306,000     |   |               |              | 2,220,000  |  
|Property, plant and equipment - net            |                                                                                                                                                                                                | 8,475,000                            |                 |             |   | 11,198,000    |             
|Purchased technology - net                     |                                                                                                                                                                                                | 8,829,000                            |                 |             |   | 10,540,000    |             
|Investment in joint venture                    |                                                                                                                                                                                                | 5,000,000                            |                 |             |   | 5,000,000     |             
|Restricted cash                                |                                                                                                                                                                                                | 740,000                              |                 |             |   | 940,000       |             
|Other assets - net                             |                                                                                                                                                                                                | 953,000                              |                 |             |   | 1,271,000     |             
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                |                                      | $               | 24,303,000  |   |               | $            | 31,169,000 |  
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|Liabilities and Stockholders Equity (Deficit) |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|Current liabilities:                           |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               | Accounts payable                                                                                                                                                                               | $                                    | 7,664,000       |             |   | $             | 4,254,000    |           
|                                               | Accrued expenses                                                                                                                                                                               |                                      | 4,311,000       |             |   |               | 1,858,000    |           
|                                               | Deferred revenue                                                                                                                                                                               |                                      | 150,000         |             |   |               |             |           
|                                               | Current portion of long-term debt                                                                                                                                                              |                                      | 20,580,000      |             |   |               | 10,480,000   |           
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                | Total current liabilities            |                 | 32,705,000  |   |               |              | 16,592,000 |  
|Deferred revenue                               |                                                                                                                                                                                                | 10,000,000                           |                 |             |   | 10,000,000    |             
|Long-term debt                                 |                                                                                                                                                                                                | 8,702,000                            |                 |             |   | 10,960,000    |             
|Stockholders equity (deficit):                |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               | Preferred stock - $.01 par value; 5,000,000 shares authorized; 793,750 and 787,500 shares of Series F Preferred Stock issued and
outstanding at March 31, 2003 and June 30, 2002, respectively |                                      | 8,000           |             |   |               | 8,000        |           
|                                               | Common stock - $.01 par value; 125,000,000 shares authorized; 20,823,961 and 17,368,849 shares issued and outstanding at March 31, 2003 and
June 30, 2002, respectively                        |                                      | 208,000         |             |   |               | 174,000      |           
|                                               | Additional paid-in capital                                                                                                                                                                     |                                      | 462,903,000     |             |   |               | 461,529,000  |           
|                                               | Accumulated deficit                                                                                                                                                                            |                                      | (490,223,000    | )           |   |               | (468,094,000 | )         
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                | Total stockholders equity (deficit) |                 | (27,104,000 | ) |               |              | (6,383,000 | )
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             
|                                               |                                                                                                                                                                                                |                                      | $               | 24,303,000  |   |               | $            | 31,169,000 |  
|                                               |                                                                                                                                                                                                |                                      |                 |             |   |               |             



|      |                                                                                                                                                                                                                                                         
|----- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|Note: | The balance sheet at June 30, 2002 has been derived from the audited financial statements at that date but does not include all of the information and footnotes required by generally accepted accounting
principles for complete financial statements.

See accompanying notes to condensed consolidated financial statements.

3



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ALLIANCE PHARMACEUTICAL CORP.CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

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|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |   |   |             |            |  
|------------------------------------ | ---------------------------- | ---------------------------- | ---------- | - | --------------------------- | ---------- | ---------- | ---- | - | ----------- | ---------- | - | - | ----------- | ---------- | -
|                                     |                              | Three months ended March 31, |            |   | Nine months ended March 31, |           
|                                     |                              |                              |            |   |                             |           
|                                     |                              | 2003                         |            |   | 2002                        |            |            | 2003 |   |             | 2002       |  
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|                                     |                              | (Unaudited)                  |            |   | (Unaudited)                 |           
|Revenues:                            |                              |                              |            |   |                             |            |            |      |   |             |            |   |   |             |           
|                                     | License and research revenue | $                            | 22,000     |   |                             | $          | 4,516,000  |      |   | $           | 53,000     |   |   | $           | 9,583,000  |  
|Operating expenses:                  |                              |                              |            |   |                             |            |            |      |   |             |            |   |   |             |           
|                                     | Research and development     |                              | 2,818,000  |   |                             |            | 8,234,000  |      |   |             | 13,008,000 |   |   |             | 25,260,000 |  
|                                     | General and administrative   |                              | 1,183,000  |   |                             |            | 2,258,000  |      |   |             | 5,980,000  |   |   |             | 6,803,000  |  
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|                                     |                              |                              | 4,001,000  |   |                             |            | 10,492,000 |      |   |             | 18,988,000 |   |   |             | 32,063,000 |  
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|Loss from operations                 |                              | (3,979,000                   | )          |   |                             | (5,976,000 | )          |      |   | (18,935,000 | )          |   |   | (22,480,000 | )         
|Investment income                    |                              | 11,000                       |            |   |                             | 45,000     |            |      |   | 60,000      |            |   |   | 228,000     |           
|Other income                         |                              |                             |            |   |                             |           |            |      |   | 329,000     |            |   |   |            |           
|Loss on investment                   |                              |                             |            |   |                             |           |            |      |   | (500,000    | )          |   |   |            |           
|Interest expense                     |                              | (1,086,000                   | )          |   |                             | (282,000   | )          |      |   | (3,083,000  | )          |   |   | (1,378,000  | )         
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|Net loss applicable to common shares | $                            | (5,054,000                   | )          |   | $                           | (6,213,000 | )          |      | $ | (22,129,000 | )          |   | $ | (23,630,000 | )         
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|Net loss per common share:           |                              |                              |            |   |                             |            |            |      |   |             |            |   |   |             |           
|                                     | Basic and diluted            | $                            | (0.26      | ) |                             | $          | (0.36      | )    |   | $           | (1.19      | ) |   | $           | (1.75      | )
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  
|Weighted average shares outstanding: |                              |                              |            |   |                             |            |            |      |   |             |            |   |   |             |           
|                                     | Basic and diluted            |                              | 19,730,000 |   |                             |            | 17,282,000 |      |   |             | 18,597,000 |   |   |             | 13,471,000 |  
|                                     |                              |                              |            |   |                             |            |            |      |   |             |            |  

See accompanying notes to condensed consolidated financial statements.

4



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ALLIANCE PHARMACEUTICAL CORP. CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

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|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |           |            |  
|----------------------------------------------------------------------- | ----------------------------------------------------------------- | -------------------------------------------- | -------------------------------------------- | --------------------------- | --------- | ----------- | ----------- | --------- | ---------- | -
|                                                                        |                                                                   |                                              |                                              | Nine months ended March 31, |          
|                                                                        |                                                                   |                                              |                                              |                             |          
|                                                                        |                                                                   |                                              |                                              | 2003                        |           |             | 2002        |          
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|                                                                        |                                                                   |                                              |                                              | (Unaudited)                 |          
|Operating activities:                                                   |                                                                   |                                              |                                              |                             |           |             |            
|                                                                        | Net loss                                                          | $                                            | (22,129,000                                  | )                           |           | $           | (23,630,000 | )        
|                                                                        | Adjustments to reconcile net loss to net cash used in operations: |                                              |                                              |                             |           |             |             |          
|                                                                        |                                                                   | Depreciation and amortization                |                                              | 4,363,000                   |           |             |             | 5,485,000 |           
|                                                                        |                                                                   | Expense associated with warrant issuance     |                                              | 226,000                     |           |             |             | 126,000   |           
|                                                                        |                                                                   | Loss on investment                           |                                              | 500,000                     |           |             |             |          |           
|                                                                        |                                                                   | Loss on sale of equity securities            |                                              |                            |           |             |             | 251,000   |           
|                                                                        |                                                                   | Non-cash compensation - net                  |                                              |                            |           |             |             | 267,000   |           
|                                                                        |                                                                   | Changes in operating assets and liabilities: |                                              |                             |           |             |             |           |           
|                                                                        |                                                                   |                                              | Restricted cash and other assets             |                             | 790,000   |             |             |           | 5,466,000  |  
|                                                                        |                                                                   |                                              | Accounts payable, accrued expenses and other |                             | 5,863,000 |             |             |           | (1,986,000 | )
|                                                                        |                                                                   |                                              | Deferred revenue                             |                             | 150,000   |             |             |           |           |  
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Net cash used in operating activities                                   |                                                                   | (10,237,000                                  | )                                            |                             |           | (14,021,000 | )          
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Investing activities:                                                   |                                                                   |                                              |                                              |                             |           |             |            
|                                                                        | Sales and maturities of short-term investments                    |                                              |                                             |                             |           |             | 49,000      |          
|                                                                        | Property, plant and equipment - net                               |                                              | 71,000                                       |                             |           |             | (15,000     | )        
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Net cash provided by investing activities                               |                                                                   | 71,000                                       |                                              |                             |           | 34,000      |            
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Financing activities:                                                   |                                                                   |                                              |                                              |                             |           |             |            
|                                                                        | Issuance of common stock                                          |                                              | 130,000                                      |                             |           |             | 13,666,000  |          
|                                                                        | Issuance of convertible preferred stock - net                     |                                              | 250,000                                      |                             |           |             | 5,704,000   |          
|                                                                        | Proceeds from long-term debt                                      |                                              | 6,860,000                                    |                             |           |             |            |          
|                                                                        | Proceeds from revolving line of credit                            |                                              | 1,784,000                                    |                             |           |             |            |          
|                                                                        | Principal payments on long-term debt                              |                                              |                                             |                             |           |             | (4,611,000  | )        
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Net cash provided by financing activities                               |                                                                   | 9,024,000                                    |                                              |                             |           | 14,759,000  |            
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Increase (decrease) in cash and cash equivalents                        |                                                                   | (1,142,000                                   | )                                            |                             |           | 772,000     |            
|Cash and cash equivalents at beginning of period                        |                                                                   | 1,416,000                                    |                                              |                             |           | 6,185,000   |            
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Cash and cash equivalents at end of period                              | $                                                                 | 274,000                                      |                                              |                             | $         | 6,957,000   |            
|                                                                        |                                                                   |                                              |                                              |                             |           |             |             |          
|Supplemental disclosure of cash flow information:                       |                                                                   |                                              |                                              |                             |           |             |            
|Interest paid                                                           | $                                                                 | 235,000                                      |                                              |                             | $         | 1,207,000   |            
|Supplemental disclosure of non-cash investing and financing activities: |                                                                   |                                              |                                              |                             |           |             |            
|Issuance of common stock upon conversion of notes                       | $                                                                 | 900,000                                      |                                              |                             | $         | 9,900,000   |            

See accompanying notes to condensed consolidated financial statements.

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ALLIANCE PHARMACEUTICAL CORP.NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

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1.     ORGANIZATION AND SUMMARY OF SIGNIFICANT
ACCOUNTING POLICIES

Organization

Alliance Pharmaceutical Corp. and its subsidiaries (collectively, the
Company or Alliance) are engaged in identifying, designing, and developing novel medical products.

Principles of Consolidation

The consolidated financial statements include the accounts of Alliance Pharmaceutical Corp., the accounts of its wholly owned subsidiary Molecular Biosystems, Inc. (MBI) from the
acquisition date of December 29, 2000, its wholly owned subsidiaries Astral, Inc., MDV Technologies, Inc., Alliance Pharmaceutical GmbH, and its majority-owned subsidiary Talco Pharmaceutical, Inc. All significant intercompany accounts and
transactions have been eliminated. Certain amounts in fiscal 2002 have been reclassified to conform to the current years presentation.

Interim Condensed Financial
Statements

The condensed consolidated balance sheet as of March 31, 2003, the condensed consolidated statements of operations for the three and nine months ended
March 31, 2003 and 2002, and the condensed consolidated statements of cash flows for the nine months ended March 31, 2003 and 2002 are unaudited. In the opinion of management, such unaudited financial statements include all adjustments, consisting
only of normal recurring accruals, necessary for a fair presentation of the results for the periods presented. Interim results are not necessarily indicative of the results to be expected for the full year. The financial statements should be read in
conjunction with the Companys consolidated financial statements and footnotes thereto included in the Companys annual report on Form 10-K for the year ended June 30, 2002.

Purchased
Technology

The majority of the purchased technology was acquired as a result of the merger of Fluoromed Pharmaceutical, Inc. in 1989. The technology acquired is the
Companys core perfluorochemical (PFC) technology and was valued based on an analysis of the future cash flows anticipated from this technology at that time. The Company identified alternative future uses for the PFC technology,
including the Oxygent(temporary blood substitute) product. Purchased technology also includes $4.5 million for technology acquired in connection with the purchase of MBI in December 2000.

The PFC technology is the basis for the Companys main drug development programs and is being amortized over a 20-year life. The PFC technology has a net book value of $6.9 million and $7.7
million, and is reported net of accumulated amortization of $16.3 million and $15.5 million at March 31, 2003 and June 30, 2002, respectively. The technology acquired from MBI has a book value of $2 million and $2.8 million, net of accumulated
amortization of $2.5 million and $1.7 million at March 31, 2003 and June 30, 2002, respectively, and is being amortized over four years.

6



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The carrying value of purchased technology is reviewed periodically based on the projected cash flows to be received from the potential sale of technology,
license fees, milestone payments, royalties and other product revenues. If such cash flows are less than the carrying value of the purchased technology, the difference will be charged to expense. A portion of the PFC technology has been licensed to
the joint venture with Baxter Healthcare Corporation (Baxter). In connection with the joint venture, the Company invested $5 million in the joint venture and received an advanced royalty payment of $10 million from the joint venture,
which is non refundable and has been recorded as deferred revenue. Net of deferred revenue, the carrying value of the PFC technology and investment is $1.9 million.

Comprehensive Income and
Loss

Financial Accounting Standards Boards (FASB) Statement No. 130, Comprehensive Income (SFAS No. 130) establishes new
rules for the reporting and display of comprehensive income and its components. SFAS No. 130 requires unrealized gains and losses on the Companys available-for-sale securities to be included in comprehensive income. During the three months
ended March 31, 2003 and 2002, the total comprehensive loss, which includes the unrealized gain or loss on available-for-sale securities, was $5,054,000 and $6,213,000, respectively. During the nine months ended March 31, 2003 and 2002, the total
comprehensive loss, which includes the unrealized gain or loss on available-for-sale securities, was $22,129,000 and $23,410,000, respectively.

Stock-based
Compensation

The Company has adopted the disclosure-only provisions of SFAS No. 123 and SFAS No. 148, an amendment to SFAS No. 123. In accordance with their
provisions, the Company applies Accounting Principles Board Opinion No. 25 and related interpretations in accounting for its stock option plans, and accordingly, no compensation cost has been recognized for stock options during the three months
ended March 31, 2003 and 2002 or the nine months ended March 31, 2003 and 2002. If the Company had elected to recognize compensation cost based on the fair value of the options granted at grant date and amortized to expense over their vesting period
as prescribed by SFAS No. 123, the Companys net loss applicable to common shares and net loss per share would have been increased to the pro forma amounts indicated below for the three-month and nine-month periods ended March 31, 2003 and
2002:

|                                                |             |                              |       |   |                             |            |       |      |   |             |       |   |   |             |       |  
|----------------------------------------------- | ----------- | ---------------------------- | ----- | - | --------------------------- | ---------- | ----- | ---- | - | ----------- | ----- | - | - | ----------- | ----- | -
|                                                |             | Three months ended March 31, |       |   | Nine months ended March 31, |           
|                                                |             |                              |       |   |                             |           
|                                                |             | 2003                         |       |   | 2002                        |            |       | 2003 |   |             | 2002  |  
|                                                |             |                              |       |   |                             |            |       |      |   |             |       |  
|Net loss as reported                            | $           | (5,054,000                   | )     |   | $                           | (6,213,000 | )     |      | $ | (22,129,000 | )     |   | $ | (23,630,000 | )    
|Fair Value of stock-based employee compensation |             | (609,000                     | )     |   |                             | (1,459,000 | )     |      |   | (2,564,000  | )     |   |   | (4,605,000  | )    
|                                                |             |                              |       |   |                             |            |       |      |   |             |       |  
|Pro forma net loss                              |             | (5,663,000                   | )     |   |                             | (7,672,000 | )     |      |   | (24,693,000 | )     |   |   | (28,235,000 | )    
|                                                |             |                              |       |   |                             |            |       |      |   |             |       |  
|Net loss per share (basic and diluted)          |             |                              |       |   |                             |            |       |      |   |             |       |   |   |             |      
|                                                | As reported | $                            | (0.26 | ) |                             | $          | (0.36 | )    |   | $           | (1.19 | ) |   | $           | (1.75 | )
|                                                | Pro forma   |                              | (0.29 | ) |                             |            | (0.44 | )    |   |             | (1.33 | ) |   |             | (2.10 | )

7



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The impact of outstanding non-vested stock options granted prior to 1996 has been excluded from the pro forma calculations; accordingly, the pro
forma adjustments for the three-month and nine-month periods ended March 31, 2003 and 2002 are not indicative of future period pro forma adjustments if the calculation reflected all applicable stock options. The fair value of options at date of
grant was estimated using the Black-Scholes option-pricing model with the following assumptions for all periods: risk-free interest rate range of 3.375% to 6.5%; dividend yield of 0%; volatility factor of 103%; and a weightedaverage expected
term of 7 years. The estimated weighted average fair value at grant date for the options granted during the three-month periods of 2003 and 2002 and the nine-month periods of 2003 and 2002 was $0.06, $2.40, $0.24 and $2.57 per option,
respectively.

Net Loss Per Share

The Company computes net loss per common share in accordance with Financial
Accounting Standards No. 128, Earnings Per Share (SFAS No. 128). SFAS No. 128 requires the presentation of basic and diluted earnings per share amounts. Basic earnings per share is calculated based upon the weighted average
number of common shares outstanding during the period while diluted earnings per share also gives effect to all potential dilutive common shares outstanding during the period such as common shares underlying options, warrants and convertible
securities, and contingently issuable shares. All potential dilutive common shares have been excluded from the calculation of diluted earnings per share as their inclusion would be anti-dilutive.

New Accounting Requirements

In August 2001, the FASB issued FAS 144, Accounting for the Impairment or Disposal of Long-Lived
Assets. FAS 144 replaces FAS 121, Accounting for the Impairment of Long-Lived Assets and for Long-Lived Assets to Be Disposed Of. The FASB issued FAS 144 to establish a single accounting model, based on the framework established in
FAS 121, as FAS 121 did not address the accounting for a segment of a business accounted for as a discontinued operation under APB 30, Reporting The Results of Operations  Reporting The Effects of Disposal of a Segment of a Business, and
Extraordinary Unusual and Infrequently Occurring Events and Transactions. FAS 144 also resolves significant implementation issues related to FAS 121. Companies are required to adopt FAS 144 for fiscal years beginning after December 15, 2001,
but early adoption is permitted. The adoption of this standard did not have a material impact on the Companys results of operations and financial position.

In June 2002,
the FASB issued Statement No. 146, or SFAS No. 146, Accounting for Costs Associated with Exit or Disposal. SFAS No. 146 addresses financial accounting and reporting for costs associated with exit or disposal activities and nullifies EITF
Issue No. 94-3, Liability Recognition for Certain Employee Termination Benefits and Other Costs to Exit an Activity (including Certain Costs Incurred in a Restructuring). The principal difference between Statement 146 and Issue 94-3
relates to Statement 146s requirements for recognition of a liability for a cost associated with an exit or disposal activity. Statement 146 requires that a liability for a cost associated with an exit or disposal activity be recognized when
the liability is incurred. Under Issue 94-3, a liability for an exit cost as generally defined in Issue 94-3 was recognized at the date of an entitys commitment to an exit plan. The provisions of this Statement 146 are effective for exit or
disposal activities that are initiated after December 31,

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2002. The adoption of this standard did not have a material impact on the consolidated financial statements.

2.     SALE OF MEDICAL IMAGING ASSETS

In November 2002, Alliance and Photogen Technologies, Inc. (Photogen)
executed a term sheet for Photogen to acquire certain of the assets of Alliance related to medical imaging, including all manufacturing and marketing rights to Imagent® (formerly Imavist), Alliances
ultrasound contrast agent that was approved by the U.S. Food and Drug Administration (FDA) for marketing in the United States in June 2002. The transaction is subject to completion of due diligence, negotiation of definitive agreements
and other contingencies, including Photogen obtaining financing for the acquisition. Under certain circumstances, if the acquisition does not occur, Alliance may be required to pay a break-up fee to Photogen. The financing structure contemplated by
the term sheet includes Photogen providing to Alliance a cash payment at closing, future payments based on product sales, and bridge financing for Imagent activities prior to the acquisition.

3.     FINANCING

As of March 31, 2003, the Company received $3.9 million through the issuance of 8% Convertible Secured
Promissory Notes (the Notes) to various institutional investors and Photogen. The Notes mature in two years from the date of issuance and are convertible into shares of Alliances common stock at $0.35 per share. Alliances
obligations under the Notes are secured by certain of its assets, including all of its assets related to and its rights and interests in Imagent and Oxygent. In connection with the issuance of the Notes, Alliance obtained the consent
and waiver of anti-dilution rights from a majority of the investors in the Companys October 2001 private placement. The Company also obtained a similar consent and waiver from the holders of its 5% Convertible Debentures (the 2004
Debentures) issued in 2000. As amended in February 2003, these consents and waivers apply to any future issuance of notes by the Company on the same terms as the Notes up to an aggregate of $5 million. The Company reduced the exercise price on
the warrants issued to the investors in the October 2001 private placement from $3.38 to $0.35 per share, in accordance with the terms of the warrants. Alliance reduced the conversion rate of the 2004 Debentures to $1.60 per share. Alliance also
agreed to issue warrants exercisable for an aggregate of 2,000,000 shares of common stock, at an exercise price of $0.50 per share, to holders of its 2004 Debentures and granted them a junior lien in the assets securing the Notes. The Company
recorded a charge to finance expense for the warrants, based upon a Black-Scholes valuation, of $80,000 in the second quarter of fiscal year 2003. Subsequent to March 31, 2003, the Company received an additional $1.2 million through the issuance of
similar Notes to Photogen.

In July and August 2002, the Company entered into two separate loan and security agreements, totaling $3 million, with an investment firm at an
effective 100% annualized interest rate. The loans are due at the earlier of 90 days after the date of the loans or the date on which the Company completes and receives the proceeds from a financing with aggregate proceeds of at least $5 million.
Amounts borrowed are secured by Imagent intangible assets. In October and November 2002, the Company did not pay the principal and accrued interest on the due dates, which constitutes an event of default under the loan terms. In connection
with the transaction, the Company issued warrants to purchase up to 200,000 shares of common stock at an exercise

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price of $3.38 per share. The Company has recorded deferred interest expense on the warrants, based upon a Black-Scholes valuation, of $48,000.

In March 2002, the Company entered into a five-year exclusive agreement with Cardinal Health, Inc. (Cardinal) to assist in the marketing of Imagent. Under the agreement,
Cardinal will perform certain packaging, distribution, and sales services for Alliance under a fee-for-service arrangement. Cardinal has extended to Alliance a revolving line of credit, up to $5 million, which will be repaid from product revenues.
Amounts due will accrue interest at a rate of 10% and will be repaid over a twelve-month period commencing in March 2004 or when the loan payable equals $5 million. The balance outstanding on this line of credit was $2.2 million and $428,000 at
March 31, 2003 and June 30, 2002, respectively.

In July 2002, Baxter purchased $250,000 of Series F Preferred Stock.

4.     LOSS ON INVESTMENT

In July 1997, the Company entered into a development agreement (the Development
Agreement) with Metracor Technologies, Inc. (Metracor) for the joint development of RODA®(Real-time Oxygen Dynamics Analyzer). In June 2001, the Development Agreement was terminated and a new
agreement was executed, whereby Metracor obtained an exclusive royalty-free license to all of Alliances rights and interest in and to RODA, and an option was granted by Alliance to Metracor to acquire all of Alliances rights to
RODA in the future upon the occurrence of certain events. Alliance also entered into an agreement to acquire approximately 2.5 million shares of Series B Preferred Stock of Metracor (Metracor B Stock) in exchange for approximately
$500,000 cash and the Metracor license. During the second quarter of fiscal 2003, the Company determined that the decline in the valuation of its investment in Metracor was other than temporary. Accordingly, the Company recorded a loss
on investment of $500,000 during the quarter.

5.     SUBSEQUENT EVENT

Subsequent to March 31, 2003,
the Company received $1.2 million through the issuance of Notes to Photogen. The Notes mature in two years from the date of issuance and are convertible into shares of Alliances common stock at $0.35 per share. Alliances obligations
under the Notes are secured by certain of its assets, including all of its assets related to and its rights and interests in Imagent and Oxygent.

Item 2.    
 Managements Discussion and Analysis of Financial Condition and Results of Operations(References to years are to the Companys fiscal years ended June 30.)

Since commencing operations in 1983, the Company has applied substantially all of its resources to research and development programs and to clinical trials. The Company has incurred losses since
inception and, as of March 31, 2003, has an accumulated deficit of $490.2 million. The Company expects to incur significant losses over at least the next few years as the Company continues its research and product development efforts and attempts to
commercialize its products.

The Companys revenues have come primarily from collaborations with corporate partners, including research and development and milestone
payments. The Companys expenses

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have consisted primarily of research and development costs and administrative costs. To date, the Companys revenues from the sale of products have not been significant.
The Company believes its future operating results may be subject to quarterly fluctuations due to a variety of factors, including the timing of future collaborations and the achievement of milestones under collaborative agreements, whether and when
new products are successfully developed and introduced by the Company or its competitors, and market acceptance of products under development.

Liquidity and Capital
Resources

Through March 2003, the Company financed its activities primarily from public and private sales of equity and funding from collaborations with corporate
partners.

As of March 31, 2003, the Company received $3.9 million through the issuance of 8% Convertible Secured Promissory Notes (the Notes) to various
institutional investors and Photogen. The Notes mature in two years from the date of issuance and are convertible into shares of Alliances common stock at $0.35 per share. Alliances obligations under the Notes are secured by certain of
its assets, including all of its assets related to and its rights and interests in Imagent and Oxygent. In connection with the issuance of the Notes, Alliance obtained the consent and waiver of anti-dilution rights from a majority of
the investors in the Companys October 2001 private placement. The Company also obtained a similar consent and waiver from the holders of its 5% Convertible Debentures (the 2004 Debentures) issued in 2000. As amended in February
2003, these consents and waivers apply to any future issuance of notes by the Company on the same terms as the Notes up to an aggregate of $5 million. The Company reduced the exercise price on the warrants issued to the investors in the October 2001
private placement from $3.38 to $0.35 per share, in accordance with the terms of the warrants. Alliance reduced the conversion rate of the 2004 Debentures to $1.60 per share. Alliance also agreed to issue warrants exercisable for an aggregate of
2,000,000 shares of common stock, at an exercise price of $0.50 per share, to holders of its 2004 Debentures and granted them a junior lien in the assets securing the Note. The Company recorded a charge to finance expense for the warrants, based
upon a Black-Scholes valuation, of $80,000 in the second quarter of fiscal year 2003. Subsequent to March 31, 2003, the Company received an additional $1.2 million through the issuance of similar Notes.

In July 1997, the Company entered into a Development Agreement with Metracor for the joint development of RODA®. In June 2001, the Development Agreement was terminated and a
new agreement was executed, whereby Metracor obtained an exclusive royalty-free license to all of Alliances rights and interest in and to RODA, and an option was granted by Alliance to Metracor to acquire all of Alliances rights
to RODA in the future upon the occurrence of certain events. Alliance also entered into an agreement to acquire approximately 2.5 million shares of Metracor B Stock in exchange for approximately $500,000 cash and the Metracor license. During
the second quarter of fiscal 2003, the Company determined that the decline in the valuation of its investment in Metracor was other than temporary. Accordingly, the Company recorded a loss on investment of $500,000 during the
quarter.

In December 2002, Alliance and Mixture Sciences, Inc. (Mixture Sciences) entered into an exclusive license agreement for all rights to a proprietary
immunotherapy platform technology developed by Astral, Inc., a wholly-owned subsidiary of Alliance. Under the terms of the

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agreement, Mixture Sciences, as licensee, will provide an undisclosed license fee and future royalties to Alliance. The parties also intend to explore the possibility of
combining their entire technologies into a single entity over the next several months.

On October 18, 2002, Alliances common stock was delisted from the NASDAQ National
Market for failure to meet the National Market continued listing requirements. The Companys common stock is now trading on NASDAQs Over-the-Counter Bulletin Board under the symbol ALLP.OB.

In August and September 2000, the Company sold $12 million of its 2004 Debentures to certain investors. On March 31, 2003, the balance outstanding on these debentures was $9.1 million. In August
2002, the Company did not pay the accrued interest on the due date, which constitutes an event of default under the debenture terms. Accordingly, the outstanding principal and accrued interest are due and payable and classified in the current
liabilities section of the Consolidated Balance Sheet at March 31, 2003. In October 2002, approximately $550,000 of the 2004 Debentures were converted into 1,576,070 shares of Alliance common stock. In March 2003, approximately $348,000 of the 2004
Debentures were converted into 995,357 shares of Alliance common stock. In connection with the issuance of the 8% Convertible Secured Promissory Notes, Alliance reduced the conversion rate of the 2004 Debentures to $1.60 per share.

In July and August 2002, the Company entered into two separate loan and security agreements, totaling $3 million, with an investment firm at an effective 100% annualized interest rate.
The loans are due at the earlier of 90 days after the date of the loans or the date on which the Company completes and receives the proceeds from a financing with aggregate proceeds of at least $5 million. Amounts borrowed are secured by
Imagent intangible assets. In October and November 2002, the Company did not pay the principal and accrued interest on the due dates, which constitutes an event of default under the loan terms. In connection with the transaction, the Company
issued warrants to purchase up to 200,000 shares of common stock at an exercise price of $3.38 per share. The Company has recorded deferred interest expense on the warrants, based upon a Black-Scholes valuation, of $48,000.

In November 2000, the Company sold $7 million of five-year 6% subordinated convertible notes to certain investors. Currently, the Company has other debt in default, which constitutes an event of
default under these convertible note terms. Accordingly, the outstanding principal and accrued interest are due and payable and classified in the current liabilities section of the Consolidated Balance Sheet at March 31, 2003.

In January 2003, Alliance signed a letter of intent with Baxter under which Alliance would acquire an option to purchase Baxters ownership interest in PFC Therapeutics, LLC (PFC
Therapeutics), the joint venture established by Alliance and Baxter in May 2000 to commercialize Oxygent, an intravascular oxygen carrier, in North America and Europe. The definitive agreement for the purchase of the option will provide
that Alliance would pay Baxter a royalty on the sales of Oxygent by PFC Therapeutics, its licensees, or its assignees following regulatory approval. In addition, Alliance would have six months to exercise its option to purchase Baxters
ownership interest in PFC Therapeutics. Under the terms of the letter of intent, Baxter would retain a right of first offer to market Oxygent in the U.S. Alliance also retained Burrill & Company, a life sciences merchant bank, to assist
Alliance and PFC Therapeutics in

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seeking strategic and financial partners to provide the resources necessary to conduct pending international Phase 3 clinical studies with Oxygent.

In January 2003, Theodore D. Roth resigned his position as Alliances President and Chief Operating Officer, but will remain a member of the Board of Directors and will serve as an unpaid
consultant to the Company. Helen M. Ranney, MD, a renowned hematologist, retired from the Board, but will continue to advise the Company regarding scientific and medical matters. In February 2003, Timothy T. Hart, Chief Financial Officer, resigned
his positions, but will serve as a consultant to the Company.

The Company had net working capital deficit of ($32.4 million) at March 31, 2003, compared to a deficit ($14.4
million) at June 30, 2002. The Companys cash, cash equivalents, and short-term investments decreased to $274,000 at March 31, 2003, from $1.4 million at June 30, 2002. The decrease resulted primarily from net cash used in operations of $10.2
million, partially offset by net proceeds of $6.9 million from long-term debt and proceeds of $1.8 million from a revolving line of credit. The Companys operations to date have consumed substantial amounts of cash and are expected to continue
to do so for the foreseeable future.

The Company continually reviews its product development activities in an effort to allocate its resources to those product candidates that
the Company believes have the greatest commercial potential. Factors considered by the Company in determining the products to pursue include projected markets and need, potential for regulatory approval and reimbursement under the existing
healthcare system, status of its proprietary rights, technical feasibility, expected and known product attributes, and estimated costs to bring the product to market. Based on these and other factors, the Company may from time to time reallocate its
resources among its product development activities. Additions to products under development or changes in products being pursued can substantially and rapidly change the Companys funding requirements.

The Company expects to incur substantial expenditures associated with product development, particularly for OxygentandImagent. The Company may seek additional collaborative
research and development relationships with suitable corporate partners for its products. There can be no assurance that such relationships, if any, will successfully reduce the Companys funding requirements. Additional equity or debt
financing may be required, and there can be no assurance that such financing will be available on reasonable terms, if at all. Because adequate funds were not available, the Company has delayed its Oxygent development efforts and it may be
required to delay, scale back, or eliminate one or more of its other product development programs, or obtain funds through arrangements with collaborative partners or others that may require the Company to relinquish rights to certain of its
technologies, product candidates, or products that the Company would not otherwise relinquish.

The Company believes it lacks sufficient working capital to fund operations for
the entire fiscal year ending June 30, 2003 and, without the bridge financing from Photogen, cannot fund its current obligations. Therefore, substantial additional capital resources will be required to fund the ongoing operations related to the
Companys research, development, manufacturing and business development activities. As noted in the report of the Companys independent auditors on the financial statements for the year ended June 30, 2002, the report included a paragraph
which noted that the Companys financial condition raises substantial doubt about its ability to

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continue as a going concern. Assuming the closing of the Photogen transaction for the sale of the medical imaging assets, management is evaluating a number of potential
alternatives available to meet the continuing capital requirements for the development of Oxygent such as public or private financings or collaborative agreements. As of March 31, 2003, the Company received a total of $3.9 million through the
issuance of 8% Convertible Secured Promissory Notes to various institutional investors and subsequent to March 31, 2003, had received an additional $1.2 million from similar notes. The Company is negotiating the issuance of comparable notes to
provide additional funding for operations. In November 2002, Alliance and Photogen executed a term sheet for Photogen to acquire certain of the assets of Alliance related to medical imaging, including all manufacturing and marketing rights to
Imagent. The transaction is subject to completion of due diligence, negotiation of definitive agreements and other contingencies, including Photogen obtaining financing for the acquisition. The financing structure contemplated by the term
sheet includes Photogen providing to Alliance a cash payment at closing, future payments based on product sales, and bridge financing for Imagent activities prior to the acquisition. The sale of Imagent has not been finalized;
therefore there can be no assurance that these financing arrangements will be consummated in the necessary time frames needed for continuing operations or on terms favorable to the Company.

The Company is taking continuing actions to reduce its ongoing expenses, including the reduction in the number of employees and the consolidation of facilities. If adequate funds are not
available, the Company will be required to significantly curtail its operating plans and may have to sell or license out significant portions of the Companys technology or potential products. The 2003 financial statements do not include any
adjustment to reflect the possible future effects on the recoverability and classification of assets or the amount and classification of liabilities that may result from the outcome of this uncertainty.

The Companys future capital requirements will depend on many factors, including, but not limited to, continued scientific progress in its research and development programs, progress with
preclinical testing and clinical trials, the time and cost involved in obtaining regulatory approvals, patent costs, competing technological and market developments, changes in existing collaborative relationships, the ability of the Company to
establish additional collaborative relationships, and the cost of manufacturing scale-up.

While the Company believes that it has material to initiate new clinical trials for
Oxygent and that it can produce materials for market launch for Imagentat its existing San Diego facility, it may need to expand its commercial manufacturing capabilities for its products in the future. Any expansion for any of its
products may occur in stages, each of which would require regulatory approval, and product demand could at times exceed supply capacity. The Company has not selected a site for such expanded facilities and cannot predict the amount it will expend
for the construction of such facilities. There can be no assurance as to when or whether the FDA will determine that such facilities comply with Good Manufacturing Practices. The projected location and construction of such facilities will depend on
regulatory approvals, product development, and capital resources, among other factors. The Company has obtained regulatory approval for its Imagent production facility.

Except for historical information, the statements made herein and elsewhere are forward-looking. The Company wishes to caution readers that these statements are only predictions and that the
Companys business is subject to significant risks. The factors discussed

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herein and other important factors, in some cases have affected, and in the future could affect, the Companys actual results and could cause the Companys actual
consolidated results for 2003, and beyond, to differ materially from those expressed in any forward-looking statements made by, or on behalf of, the Company. These risks include, but are not limited to, the inability to obtain adequate financing for
the Companys development efforts; the inability to enter into collaborative relationships to further develop and commercialize the Companys products; changes in any such relationships, or the inability of any collaborative partner to
adequately commercialize any of the Companys products; the uncertainties associated with the lengthy regulatory approval process, including uncertainties associated with FDA decisions and timing on product development or approval; and the
uncertainties associated with obtaining and enforcing patents important to the Companys business; and possible competition from other products. Furthermore, even if the Companys products appear promising at an early stage of development,
they may not reach the market for a number of important reasons. Such reasons include, but are not limited to, the possibilities that the potential products will be found ineffective during clinical trials; failure to receive necessary regulatory
approvals; difficulties in manufacturing on a large scale; failure to obtain market acceptance; and the inability to commercialize because of proprietary rights of third parties. The research, development, and market introduction of new products
will require the application of considerable technical and financial resources, while revenues generated from such products, assuming they are developed successfully, may not be realized for several years. Other material and unpredictable factors
which could affect operating results include, without limitation, the uncertainty of the timing of product approvals and introductions and of sales growth; the ability to obtain necessary raw materials at cost-effective prices or at all; the effect
of possible technology and/or other business acquisitions or transactions; and the increasing emphasis on controlling healthcare costs and potential legislation or regulation of healthcare pricing. Further cautionary information is contained in
documents the Company files with the Securities and Exchange Commission from time to time, including the last Form 10-K, and those risk factors set forth in the most recent registration statement on Form S-3 (File No. 333-72844) and Form S-4 (File
No. 333-49676).

Results of Operations

Nine Months ended March 31, 2003 as Compared with Nine Months ended
March 31, 2002

The Companys license and research revenue decreased to $53,000 for the nine months ended March 31, 2003, compared to $9.6 million for the nine months
ended March 31, 2002. The decrease was primarily a result of $4.5 million in revenue recorded in connection with the Inhale supplemental agreement for PulmoSpheres technology in March 2002 and $5 million received from Mallinckrodt in
connection with the amendment of the Optison Product Rights Agreement in August 2001.

Research and development expenses decreased by 49% to $13 million for the nine
months ended March 31, 2003, compared to $25.3 million for the nine months ended March 31, 2002. The decrease in expenses was primarily due to a $5.2 million decrease in staffing costs for employees engaged in research and development activities, a
$1.5 million decrease in repairs and maintenance expense, a $1.5 million decrease in payments to outside researchers for clinical trials and other product development work, a $1.2 million decrease in facility rent expense, a

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$1.2 million decrease in supplies and chemicals, a $866,000 decrease in depreciation expense, as well as other decreases related to the Company's research and development
activities.

General and administrative expenses were $6 million for the nine months ended March 31, 2003, compared to $6.8 million for the nine months ended
March 31, 2002. The decrease in general and administrative expenses was primarily due to a decrease of $1 million related to the fiscal year 2002 non-recurring adjustment of a prepaid royalty as a result of the amendment of the
Optison Product Rights Agreement with Mallinckrodt in August 2001, a $1.1 million decrease in staffing costs, a $341,000 decease in travel, seminars and related expenses, a $225,000 decrease in depreciation expense, as well as other
decreases related to the Company's general and administrative activities. The decreases were offset by an increase of $2 million in professional fees primarily related to Imagent marketing activities.

Investment income was $60,000 for the nine months ended March 31, 2003, compared to $228,000 for the nine months ended March 31, 2002. The decrease was primarily a result of lower
average cash balances.

Other income was $329,000 for the nine months ended March 31, 2003. This was primarily a result of proceeds recorded from the settlement of a
lawsuit.

Loss on investment of $500,000 was recorded in fiscal year 2003 when the Company determined that the decline in the valuation of its investment in Metracor was
other than temporary.

Interest expense was $3.1 million for the nine months ended March 31, 2003, compared to $1.4 million for the nine months ended
March 31, 2002. The increase was primarily a result of higher average long-term debt balances and higher interest rates.

Three Months ended March 31, 2003 as
Compared with Three Months ended March 31, 2002

The Companys license and research revenue decreased to $22,000 for the three months ended March 31, 2003,
compared to $4.5 million for the three months ended March 31, 2002. In fiscal 2002, Alliance recorded $4.5 million in revenue in connection with the Inhale supplemental agreement for PulmoSpheres® technology in March
2002.

Research and development expenses decreased by 66% to $2.8 million for the three months ended March 31, 2003, compared to $8.2 million for the three months
ended March 31, 2002. The decrease in expenses was primarily due to a $2.3 million decrease in staffing costs for employees engaged in research and development activities, a $640,000 decrease in repairs and maintenance expense, a $623,000
decrease in payments to outside researchers for clinical trials and other product development work, a $534,000 decrease in facility rent expense, a $463,000 decrease in supplies and chemicals, a $421,000 decrease in depreciation expense, as well as
other decreases related to the Company's research and development activities.

General and administrative expenses were $1.2 million for the three months ended
March 31, 2003, compared to $2.3 million for the three months ended March 31, 2002. The decrease in general and administrative expenses was primarily due to a $610,000 decrease in staffing costs, a $153,000 decrease in travel,
seminars and related expenses, a $147,000 decrease

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in depreciation expense, as well as other decreases related to the Company's general and administrative activities.

Investment income and other was $11,000 for the three months ended March 31, 2003, compared to $45,000 for the three months ended March 31, 2002. The decrease was primarily a result of
lower average cash balances.

Interest expense was $1.1 million for the three months ended March 31, 2003, compared to $282,000 for the three months ended March 31,
2002. The increase was primarily a result of higher average long-term debt balances and higher interest rates.

Alliance expects to continue to incur substantial expenses
associated with its research and development programs. Operating losses may fluctuate from quarter to quarter as a result of differences in the timing of revenues earned and expenses incurred and such fluctuations may be substantial. The
Companys historical results are not necessarily indicative of future results.

Item 3.     
Quantitative and Qualitative Disclosures About Market Risk

The Company is or has been exposed to changes in interest rates primarily from its
long-term debt arrangements and, secondarily, its investments in certain securities. Under its current policies, the Company does not use interest rate derivative instruments to manage exposure to interest rate changes. The Company believes that a
hypothetical 100 basis point adverse move in interest rates along the entire interest rate yield curve would not materially affect the fair value of the Company's interest sensitive financial instruments at March 31, 2003.

Item 4.     
Controls And Procedures

(a)     The Company maintains disclosure controls and procedures that are designed to ensure that information required to be
disclosed in its Exchange Act Filings and Reports is recorded, processed, summarized and reported within the timelines specified in the Security and Exchange Commissions rules and forms, and that such information is accumulated and
communicated to the Companys management, including its Chief Executive Officer and Chief Financial Officer, to allow timely disclosure. In designing and evaluating the disclosure controls and procedures, management recognized that any
controls and procedures, no matter how well designed and operated, can only provide reasonable assurance of achieving the desired control objectives.

Within 90 days prior to
the date of this report, the Company carried out an evaluation, under the supervision and with the participation of its management, including its Chief Executive Officer and Chief Financial Officer, of the effectiveness of the design and operation
of its disclosure controls and procedures. Based on the foregoing, the Companys Chief Executive Officer and Chief Financial Officer concluded that its disclosure controls and procedures were effective.

(b)     There have been no significant changes in the Companys internal controls or in other factors that could significantly affect these controls subsequent to the date it carried out this
evaluation.

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Part II     
Other Information:

Item 6.     
Exhibits and Reports on Form 8-K

|    |                     |              
|--- | ------------------- | -------------
|(a) | Exhibits           
|    |                     |              
|    | 99.1                | Certification
|    |                     |              
|(b) | Reports on Form 8-K
|    |                     |              
|    | NONE.              

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant
has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

|                   |                               |                                                             
|------------------ | ----------------------------- | ------------------------------------------------------------
|                   | ALLIANCE PHARMACEUTICAL CORP.
|                   | (Registrant)                 
|                   |                               |                                                             
|                   |                               | /s/ DUANE J. ROTH                                           
|                   |                               |                                                             
|                   |                               | Duane J. Roth                                               
|                   |                               | Chairman, Chief Executive Officerand Chief Financial Officer
|                   |                               |                                                             
|Date: May 15, 2003 |                               |                                                             

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CERTIFICATION

I, Duane J. Roth, Chief Executive Officer and Chief Financial Officer
of Alliance Pharmaceutical Corp. (the Company), certify that:

1.     I have reviewed this quarterly report on Form 10-Q of the
Company;

2.     Based on my knowledge, this quarterly report does not contain any untrue statement of a material fact or omit to state a material
fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this quarterly report;

3.     Based on my knowledge, the financial statements, and other financial information included in this quarterly report, fairly present in all material respects
the financial condition, results of operations and cash flows of the Company as of, and for, the periods presented in this quarterly report;

4.     I am responsible for establishing and maintaining disclosure controls and procedures (as such term is defined in Exchange Act Rules 13a-14 and 15d-14 for the Company and I have:

(a)     designed such disclosure controls and procedures to ensure that material information
relating to the Company, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this quarterly report is being prepared;

(b)     evaluated the effectiveness of the Companys disclosure controls and procedures as of
a date within 90 days prior to the filing date of this quarterly report (Evaluation Date); and

(c)     presented in this quarterly report my conclusions about the effectiveness of the disclosure controls and procedures based on my evaluation as of the
Evaluation Date.

5.     I have disclosed, based on my most recent evaluation, to the Companys auditors and the audit committee of the
Companys Board of Directors:

(a)    all significant deficiencies in the design
or operation of internal controls which could adversely affect the Companys ability to record, process, summarize and report financial data and have identified for the Companys auditors any material weaknesses in internal controls;
and

(b)     any fraud, whether or not material, that involves management or other employees who have a significant role in the Companys internal
controls; and

6.     I have indicated in this quarterly report whether or not there were significant changes in internal controls or in other
factors that could significantly affect internal controls subsequent to the date of our most recent evaluation, including any corrective actions with regard to significant deficiencies and material weaknesses.

Dated:  May 15, 2003

|    |                                                     | 
|--- | --------------------------------------------------- | 
|By: | /s/ DUANE J. ROTH                                   | 
|    |                                                     | 
|    | Duane J. Roth                                       | 
|    | Chief Executive Officer and Chief Financial Officer | 

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