**Exhibit      3.5**

**CERTIFICATE      OF CORRECTION **

**OF      THE**

**CERTIFICATE      OF AMENDMENT**

**OF      THE**

**CERTIFICATE      OF INCORPORATION**

**OF**

**ALLIANCE      PHARMACEUTICAL CORP.**

|   | “THIRD:                The amendment effected by this Certificate of Amendment is as follows:                The                third paragraph of Section 4 of the Certificate of Incorporation                is                amended to increase the total number of shares of Common Stock, par                value                $.01 per share, that the Corporation is authorized to issue from                125,000,000 shares to 150,000,000 shares, an increase of 25,000,000                shares. Prior to this Certificate of Amendment, the Corporation was                authorized to issue 130,000,000 shares of stock, of which 125,000,000                shares were designated Common Stock, par value $.01 per share, and                5,000,000 shares were designated Preferred Stock, par value $.01                per                share. Pursuant to this Certificate of Amendment, the Corporation                will be                authorized to issue 155,000,000 shares of stock, of which 150,000,000                shares will be designated Common Stock, par value $.01 per share,                and                5,000,000 shares will be designated Preferred Stock, par value $.01                per                share. Except for the increase in the number of shares of Common                Stock,                par value $.01 per share, that the Corporation is authorized to issue,                the                Corporation’s Common Stock, par value $.01 per share, will not be affected                in any manner. The 5,000,000 shares of Preferred Stock, par value                $.01 per                share, that the Corporation is authorized to issue will not be affected                by                such amendment.” |
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| Date: December 15, 2006 | By:                                                  |                                                      /s/ B. Jack                DeFranco                                       |
|                         | Name: B. Jack DeFranco                                    |
|                         | Title:              President and Chief Operating Officer |