Initial to indicate certification as to information on this page

(full text of certification is on page one).

Date

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. 

Use additional sheet(s) if necessary.

2. Case # and Name 3. Date and Type of DCI and Number

4. EPA Product 

Registration

5. I wish to cancel 

this product 

registration 

voluntarily

6. Generic Data 7. Product Specific Data

6a. I am claiming a Generic Data 

Exemption because I obtain the 

active ingredient from the source 

EPA registration number listed 

below.

6b. I agree to satisfy Generic Data

Requirements as indicated on the 

attached form entitled 

"Requirements Status and 

Registrant's Response."

7a. My product is an MUP and I 

agree to satisfy the MUP 

requirement on the attached form

entitled "Requirements Status and

Registrant's Response."

7b. My product is an EUP and I 

agree to satisfy the EUP 

requirement on the attached form 

entitled "Requirements Status and 

Registrant's Response."

OMB Approval 2070-0174

1. Company Name and Address

 

0248 - Malathion (NO INERT USE)

Chemical # and Name: 057701

Malathion

12-Aug-2010

GENERIC

ID # GDCI-057701-830

United States Environmental Protection Agency

Washington, D.C. 20460

DATA CALL-IN RESPONSE

Page of 1 1

8. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

Signature and Title of Company's Authorized Representative ______________________________________________________

10. Name of Company

N/A N/A

9. Date

11. Phone Number 
Initial to indicate certification as to information on this page (full text of certification is on page one) 

13. Phone Number

10. Certification: I certify that the statements made on this form and all attachments are true, accurate, and complete. I acknowledge that any 

knowingly false or misleading statement may be punishable by fine, imprisonment or both under applicable law.

12. Name of Company

11. Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

Signature and Title of Company's Authorized Representative _________________________________________________________________

 

Environmental Fate Data Requirements (Conventional 

Chemical)

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

835.1230

835.4100

835.4300

835.6100

835.6200

850.1010

850.1075

850.1350

Sediment and soil absorption/desorption for parent 

and degradates

Aerobic soil metabolism

Aerobic aquatic metabolism

Terrestrial field dissipation

Aquatic field dissipation

Aquatic invertebrate acute toxicity, test, freshwater 

daphnids

Fish acute toxicity test, freshwater and marine

Mysid chronic toxicity test

0248 - Malathion (NO INERT USE)

Chemical # and Name: 057701

Malathion

12-Aug-2010

GENERIC

ID # GDCI-057701-830

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

EP; PAI; TGAI

TGAI or PAIRA

TGAI or PAIRA

TEP

TEP

EP; PAI; TGAI

EP; PAI; TGAI

TGAI

12

24

24

24

24

12

12

12

Page 1 of 

(4, 20)

(5, 7, 8)

(6)

(8, 9, 12)

(9, 11)

(1, 10, 14)

(3, 10, 14)

(15, 16, 19)

N

N

N

N

N

N

N

N

2
Date

OMB Approval 2070-0174

United States Environmental Protection Agency 

Washington, D.C. 20460

REQUIREMENTS STATUS AND REGISTRANT'S RESPONSE

INSTRUCTIONS: Please type or print in ink. Please read carefully the attached instructions and supply the information requested on this form. Use additional sheet(s) if necessary.

4. Guideline

Requirement

Number

5. Study Title Progress 

Reports

1 2 3

6. Use 

Pattern

7. Test 

Substance

8. Time

Frame 

(Months)

9. Registrant

Response

P

R

O

T

O

C

O

L

1. Company Name and Address 2. Case # and Name 3. Date and Type of DCI and Number

 

Terrestrial and Aquatic Nontarget Organisms Data 

Requirements (Conventional Chemical)

850.1400

850.2100

Fish early-life stage toxicity test

Avian acute oral toxicity test

0248 - Malathion (NO INERT USE)

Chemical # and Name: 057701

Malathion

12-Aug-2010

GENERIC

ID # GDCI-057701-830

U,HH,J,A,II,K,C,B,Q

U,HH,J,A,II,K,C,B,Q

TGAI

EP; PAI; TGAI

12

12

Page 2 of 

(15, 17, 18)

(2, 13)

N

N

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0248 - Malathion (NO INERT USE)

GDCI-057701-830

1

2

3

4

5

6

7

8

9

10

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

The malathion degradate malaoxon should be the test substance. An acute study in daphids is required.

The following acute oral studies should be included: Test substance malathion, acute LD50 in Passerine Species; Test Substance malaoxon, acute LD50 in the same passerine species as used 

for the malathion study.

Test substance should be the malathion degradate malaoxon. Acute studies in bluegill sunfish and rainbow trout are required.

Test substance should be the malathion degradate malaoxon.

Study should measure the same degradates as the respective malathion and malaoxon hydrolysis studies.

Study should examine the environmental fate of malathion and its degradates in acidic soil and water conditions (pH of approximately 5.5 to 6.5).

Should examine the fate of malathion in acidic soil and water conditions (pH of approximately 5.5 to 6.5). Aerobic soil metabolism data is also required on the malathion degradate malaoxon 

under the same conditions.

Required for aquatic food and nonfood crop uses for aquatic sites that are intermittently dry. Such sites include, but are not limited to cranberry bogs and rice paddies.

Only environmental chemistry methods are needed. Malathion and malaoxon should be studied.

Freshwater fish LC50 (the most sensitive of the species tested), freshwater invertebrate EC50 (preferably Daphnia), and acute LC50/EC50 estuarine and marine organisms studies using the EP

or TEP are required for any product which meets any of the following conditions: (i) The end-use pesticide will be introduced directly into an aquatic environment (e.g., aquatic herbicides and 

mosquito larvicides) when used as directed; (ii) the maximum expected environmental concentration (MEEC) or the estimated environmental concentration (EEC) in the aquatic environment is 

Case # and Name:

DCI Number:

Page: 1 of

Footnotes: The following footnotes are referenced in column two (5. Study Title) of the Requirements Status and Registrant's Response form. 

These footnotes apply in addition to any test notes included in 40 CFR Part 158 with respect to the particular data requirement.

Use Categories Key:

A - Terrestrial food crop

B - Terrestrial feed crop

C - Terrestrial nonfood crop

J - Forestry use

K - Residential

Q - Residential outdoor use

U - Residential and public access premises

HH - Occupational Use Conventional Chemical

II - Residential Use Conventional Chemical

2
United States Environmental Protection Agency 

Washington, D.C. 20460

FOOTNOTES AND KEY DEFINITIONS FOR GUIDELINE REQUIREMENTS

0248 - Malathion (NO INERT USE)

GDCI-057701-830

11

12

13

14

15

16

17

18

19

20

Key: Residue of Concern = Residue of Concern; TEP = Typical End Use Product [TEP]; TGAI = Technical Grade Active Ingredient [TGAI]; TGAI/PAIRA = Technical Grade of the Active Ingredient or Pure Active 

Ingredient, Radio Labelled; TGAI, TEP = Technical Grade of the Active Ingredient or Technical End-Use Product; TGAI/PAI = Technical Grade Active Ingredient, Pure Active Ingredient

equal to or greater than one-half the LC50 or EC50 of the TGAI when the EP is used as directed; (iii) an ingredient in the end-use formulation other than the active ingredient is expected to 

enhance the toxicity of the active ingredient or to cause toxicity to aquatic organisms.

Environmental chemistry methods used to generate data associated with this study must include results of a successful confirmatory method trial by an independent laboratory. Test standards 

and procedures for independent laboratory validation are available as addenda to the guideline for this test requirement.

Environmental chemistry methods used to generate data associated with this study must include results of a successful confirmatory method trial by an independent laboratory. The 

environmental chemistry methods must include a statement of no data confidentiality claims, i.e., non-CBI. Test standards and procedures for independent laboratory validation are available as 

addenda to the guideline for this test requirement.

Data using the TGAI are required to support all outdoor end-use product uses including, but not limited to turf. Data are generally not required to support end-use products in the form of a gas, a 

highly volatile liquid, a highly reactive solid, or a highly corrosive material.

Data using the TGAI are required to support all outdoor end-use product uses including turf. Data are generally not required to support end use products in the form of a gas, a highly volatile 

liquid, a highly reactive solid, or a highly corrosive material. 

Data are required on estuarine species if the product is: (i) intended for direct application to the estuarine or marine environment; (ii) expected to enter this environment in significant 

concentrations because of its expected use or mobility patterns, and (iii) if the acute LC50 or EC50 < 1 mg/l; or (iv) if the estimated environmental concentration in water is equal to or greater 

than 0.01 of the acute EC50 or LC50 and any of the following conditions exist: (a) studies of other organisms indicate the reproductive physiology of fish and/or invertebrates may be affected; 

(b) physicochemical properties indicate bioaccumulation of the pesticide; (c) the pesticide is persistent in water (e.g., half-life in water greater than 4 days).

Data are generally not required for outdoor residential uses, other than turf, unless data indicate that pesticide residues from the proposed use(s) can potentially enter waterways.

Data are generally not required for other, non-turf, outdoor residential uses, i.e., gardens and ornamentals.

Chronic toxicity study should examine the effects of malathion on estuarine/marine fish.

Chronic toxicity study should examine the effect of malathion on estuarine/marine invertebrates.

Adsorption and desorption using a batch equilibrium method is preferred. However in some cases, for example, where the pesticide degrades rapidly, soil column leaching with unaged or aged 

columns may be more appropriate to fully characterize the potential mobility of the parent compound and major transformation products.

Case # and Name:

DCI Number:

Page: 2 of 2
United States Environmental Protection Agency 

Washington, D.C. 20460

LIST OF ALL REGISTRANTS SENT THIS DATA CALL-IN NOTICE

Case # and Name: 0248 - Malathion (NO INERT USE)

Page: 1 of 1

4787 CHEMINOVA A/S

Co. Nr. Company Name Agent For Company

CHEMINOVA INC. 1600 WILSON BLVD., SUITE 700

Address City ZIP

ARLINGTON 22209 

OMB Approval 2070-0174

State

VA

 DCI Number: GDCI-057701-830
LINKS TO FORMS:

The pesticide registration forms that are listed below can be found at:

http://www.epa.gov/opprd001/forms/

Link to Confidential Statement of Formula and Instructions (Form # 8570-4)

http://www.epa.gov/opprd001/forms/8570-4.pdf

Certification of Attempt to Enter Into an Agreement With Registrants for 

Development of Data (Form # 8570-32)

http://www.epa.gov/opprd001/forms/8570-32.pdf

Certification With Respect to Citation of Data (Form # 8570-34)

http://www.epa.gov/opprd001/forms/8570-34.pdf