FIRST
AMENDMENT TO PURCHASE AND SALE AGREEMENT


 


THIS
FIRST AMENDMENT TO PURCHASE AND SALE AGREEMENT (“Amendment”) is made as of this __ day of March, 2018,
by and between HEMISPHERX BIOPHARMA, INC., a Delaware corporation (the “Seller”), and 783 JERSEY
AVENUE, LLC, a New Jersey limited liability company, successor-by-assignment to Capital Realty & Investment Co., LLC (the
“Purchaser”).


 


WITNESSETH:


 


WHEREAS,
Seller and Purchaser entered into a Purchase and Sale Agreement dated as of January 8, 2018 (the “Original Agreement”)
with respect to the “Property” defined therein located at 783 Jersey Avenue, New Brunswick, New Jersey; and


 


WHEREAS,
Seller and Purchaser have agreed to amend the Original Agreement as set forth in this Amendment.


 


NOW,
THEREFORE, In consideration of the mutual covenants and agreements set forth herein, for valuable consideration, the receipt of
which is hereby acknowledged, the parties hereto do hereby agree as follows:


 


ARTICLE
I. definitions


 


All
capitalized terms not defined in this Amendment shall have the meanings ascribed to them in the Original Agreement. All references
to the “Agreement” contained in this Amendment and in the Original Agreement shall hereafter be deemed to refer to
the Original Agreement, as modified and amended by this Amendment. The Recitals above shall be a part of this Amendment, and are
incorporated by reference.


 


ARTICLE
II. Amendment of original agreement


 


	2.1	Purchase
    Price. Section 2.1 of the Original Agreement is hereby modified to increase the Purchase Price to FOUR MILLION
    EIGHTY THOUSAND AND 00/100 DOLLARS ($4,080,000.00).
	 	 
	2.2	Inventory
    of Personal Property. Exhibit B-1 attached to the Original Agreement is hereby replaced with Exhibit
    B-1 attached to this Amendment.
	 	 
	2.3	Seller
    Lease. Exhibit B-3 attached to the Original Agreement is hereby replaced with Exhibit B-3
    attached to this Amendment.


 






    	-1-



    	 



    

 


ARTICLE
III. MISCELLANEOUS


 


	3.1	Other
    Provisions Unaffected. Except as modified hereby, all other provisions of the Original Agreement shall remain in in full
    force and effect, unmodified by this Amendment, and are hereby fully ratified, confirmed and adopted by Purchaser and Seller.
	 	 
	3.2	Entire
    Agreement. The Original Agreement, as modified by this Amendment, together with the Exhibits hereto, constitutes the entire
    understanding between the parties with respect to the Transaction and all prior agreements, understandings, representations
    and statements, oral or written, are merged into this Amendment.
	 	 
	3.3	Governing
    Law. This Amendment shall be governed by, and construed in accordance with, the law of the State of New Jersey.
	 	 
	3.4	Severability.
    If any term or provision of this Amendment or the application thereof to any persons or circumstances shall, to any extent,
    be invalid or unenforceable, the remainder of this Amendment or the application of such term or provision to persons or circumstances
    other than those as to which it is held invalid or unenforceable shall not be affected thereby, and each term and provision
    of this Amendment shall be valid and enforced to the fullest extent permitted by Law.
	 	 
	3.5	Counterparts.
    This Amendment may be executed in counterparts, each of which shall be an original and all of which counterparts taken together
    shall constitute one and the same agreement. Any executed counterpart delivered by electronic mail or telephone facsimile
    shall have the same force and effect as an original counterpart.


 


[REMAINDER
OF THIS PAGE LEFT INTENTIONALLY BLANK]


 




    	-2-



    	 



    

 


IN
WITNESS WHEREOF, each party hereto has caused this Amendment to be duly executed on its behalf on the day and year first
above written.


 


	 	SELLER:
	 	 	 
	 	HEMISPHERX
    BIOPHARMA, INC. A Delaware corporation
	 	 	 
	 	By:	/s/
    Wayne Springate
	 	Name:
    	Wayne
    Springate
	 	Title:
    	Sr.
    VP     of Operations
	 	 	 
	 	PURCHASER:
	 	 	 
	 	783
    JERSEY AVENUE, LLC, a New Jersey limited liability
	 	 	 
	 	By:	Kerron,
    LLC, a New Jersey limited liability company, an authorized manager
	 	 	 
	 	By:	/s/
    Aaron T. Feiler
	 	Name:
    	Aaron
    T. Feiler
	 	Title:
    	Member


 




    	-3-



    	 



    

 


EXHIBIT
B-1


 


INVENTORY
OF PERSONAL PROPERTY


 


	RM#
    129	Equipment
    Description
	HB#
    2222	Thermo
    Electron -70C Freezer
	HB#2051	Forma
    Scientific -70C Freezer
	HB#
    2262	Thermo
    Electron -70C Freezer
	HB#2294	Thermo
    Electron -70C Freezer
	HB#2261	Thermo
    Electron -70C Freezer
	HB#2223	Thermo
    Electron -70C Freezer
	HB#
    2245	Leer
    -20C Walk In Freezer
	HB#3256	VWR
    Symphony -70C Freezer
	HB#
    3346	Whirlpool
    -20C Freezer
	HB#
    3255	VWR
    Symphony -70C Freezer
	HB#
    2334	Dometic
    -70C Freezer
	HB#
    3341	Thermo
    Scientific -70C Freezer
	HB#
    3005	Darwin
    Stability Refrigerator
	HB#
    3340	Thermo
    Scientific -70C Freezer
	HB#
    2265	Thermo
    Electron -70C Freezer
	HB#
    1995	Magic
    Chef -20C Freezer
	HB#
    2333	Dometic
    -70C Freezer
	HB#
    2244	Leer
    -20C Walk In Freezer
	HB#
    3006	VWR
    Humidity Stability Chamber
	HB#2335	Dometic
    -70C Freezer
	 	 
	RM
    #330	Equipment
    Description
	HB#
    1958	Forma
    Scientific Dry Incubator
	HB#
    3148	Thermo
    Scientific Dry Incubator
	HB#
    3149	Thermo
    Scientific Dry Incubator
	HB#
    1666	SterilGARD
    Biological Safety Cabinet
	HB#
    1789	SterilGARD
    Biological Safety Cabinet
	HB#
    1278	Quebec
    Colony Counter
	HB#
    1997	Met
    One Particle Counter
	HB#
    1779	RCS
    Air Sampler
	HB#
    1260	Leitz
    Microscope
	 	 
	RM#325	Equipment
    Description
	HB#
    2221	Thermo
    Electron -70C Freezer
	HB#
    1883	Gibson
    -20C Freezer
	HB#
    2214 (Top & Bottom)	Forma
    Scientific Water Jacketed CO2 Incubator
	HB#
    3151/ HB#3150	Thermo
    Scientific Water Jacketed CO2 Incubator
	HB#
    2231	Mettler
    Toledo pH meter
	HB#3207	Thermo
    Scientific UV Spectrophotometer
	HB#
    3363	Fisher
    Scientific Dry Incubator
	HB#2186	Mettler
    PM 200 Balance



 




    	B1-1



    	 



    

 





	RM
    323	Equipment
    Description
	HB#
    2343	SterilGARD
    Biological Safety Cabinet
	HB#
    2344	SterilGARD
    Biological Safety Cabinet
	HB#
    2282	VWR
    Waterbath
	HB#3174	VWR
    Waterbath
	HB#1204	Wild
    M40 Microscope
	N/A	DELL
    Computer for CPE Calculations
	HB#
    3283	TRUE
    Refrigerator
	HB#
    3296	TRUE
    Refrigerator
	HB#
    3168	Fisher
    Depyrogenation Oven
	HB#
    3362	Kenmore
    Freezer
	 	 
	RM
    327	Equipment
    Description
	HB#
    1131	Forma
    Quick Glassware Dryer
	HB#
    2306	Primus
    Sterilizer
	HB#
    2300	Miele
    Professional Laboratory Equipment Washer
	 	 
	RM#
    322	Equipment
    Description
	HB#
    2330	Tecan
    Plate Reader
	HB#
    1101	Mettler
    Toledo Balance
	Computer
    #55	DELL
    Computer for Tecan Plate Reader
	HB#
    1228	Bellco
    Glass Biological Safety Cabinet
	HB#
    3325	Nuaire
    Biological Safety Cabinet
	HB#
    1289	Bausch
    & Lomb Microscope
	HB#
    1127	Beckman
    Centrifuge
	HB#
    1631	Titertek
    Plate Reader
	HB#
    3001	Chromate
    Plate Reader
	HB#
    3404	Plate
    Gyratory Shaker
	Computer
    # 54	DELL
    Computer for CPE Calculation
	 	 
	RM#324	Equipment
    Description
	HB#
    3054	VWR
    Waterbath
	HB#
    1269	Diavert
    Microscope
	HB#
    1205	BioGARD
    Biological Safety Cabinet
	HB#
    3262/ 3263	Forma
    Scientific Water Jacketed CO2 Incubator
	HB#
    3291	SANYO
    Water Jacketed CO2 Incubator
	HB#1255	Bransonic
    Sonicator
	 	 
	RM#310
    (SSI)	Equipment
    Description
	HB#
    2353	Millipore
    Filter Integrity Tester
	HB#
    2354	Guava
    Cell counter
	HB#
    2251	Mettler
    Toledo Balance
	HB#
    3154	Fisher
    Scientific IsoTemp Water Bath
	HB#
    2345	SterilGARD
    Biological Safety Cabinet
	HB#
    1646	Sorvall
    Centrifuge
	HB#
    1677	Waterbath




 




    	B1-2



    	 



    

 





	RM
    #226	Equipment
    Description
	HB#
    3349	Sievers
    M-9 TOC Analyzer
	Computer
    #53	DELL
    Computer for TOC Analyzer
	HB#
    3232	Mettler
    Toledo Conductivity Meter
	HB#3332	Mettler
    Toledo Conductivity Meter
	HB#
    2104	Fisher
    Scientific Oven
	HB#
    3098	Desiccator
	HB#
    2347	Glas-Col
    Heating Mantle
	HB#
    2346	Maflar
    Furnace
	HB#
    1498	Sartorius
    Balance
	HB#
    1502	UV-160
    Shimadzu UV Spectrophotometer
	HB#
    1776	Perkin
    Elmer 1420 Infrared Spectrophotometer
	HB#
    1589	Fume
    Hood
	 	 
	RM#
    225	Equipment
    Description
	HB#2359	Agilent
    HPLC
	HB#
    1824	RCA
    Refrigerator
	HB#
    2172	Agilent
    HPLC
	HB#
    3008	Agilent
    GC
	HB#
    3372	Advance
    Osmometer
	Computer
    #47	DELL
    Computer for HPLC & GC
	HB#1888	Savant
    Speed Vac
	 	 
	RM#218	Equipment
    Description
	HB#
    2212	Bally
    Walk In Refrigerator
	HB#
    1919	Frigidaire
    -20C Freezer
	HB#3369	Eppendorf
    Centrifuge
	HB#
    2215	Edge
    Gard Hood
	HB#
    2216	Edge
    Gard Hood
	HB#
    2274	Denver
    Conductivity Meter
	HB#
    1518	Shimadzu
    Densitometer
	HB#
    2283	Brookfield
    Viscometer
	HB#
    2291	JASCO
    CD Spectrophotometer
	HB#
    2289	Mettler
    Toledo pH meter
	HB#
    3146	VWR
    Viscometer (waterbath)
	HB#
    2340	Malvern
    GPC
	HB#
    2227	Precision
    Waterbath
	HB#
    2275	Beckman
    HPLC
	HB#
    2242	Beckman
    HPLC
	HB#
    2318	Beckman
    Microfuge 12
	Computer
    # 48	DELL
    Computer for JASCO CD
	Computer
    # 49	IBM
    Computer for Beckman HPLCs
	Computer
    # 50	DELL
    Computer for GPC




 




    	B1-3



    	 



    

 





	RM#221	Equipment
    Description
	HB#
    3299	Labconco
    Freezer dry System
	HB#
    3417	UVP
    UVGL-58 Paper Chromatography
	HB#
    3448	Fotodyne
    Gel Imaging System
	HB#2277	Beckman
    Ultracentrifuge
	HB#
    2246	Beckman
    Ultracentrifuge
	HB#
    2188	Mettler
    Toledo Balance
	HB#
    2187	Mettler
    Toledo Balance
	HB#
    1588	Labconco
    Hood
	HB#
    3152	Mettler
    Toledo Karl Fisher
	HB#
    2349	UVP
    Gel Imaging System
	Computer
    #33	ACER
    Computer for UVP
	Computer
    #44	IBM
    Computer for Beckman
	Computer
    #44	IBM
    Computer for Beckman
	 	 
	RM#
    222	Equipment
    Description
	HB#
    1799	Fisher
    Scientific Incubator
	HB#
    3046	Thermo
    Scientific Nanodrop
	HB#
    2219	Sartorius
    Balance
	HB#
    3274	Sorvall
    Centrifuge
	HB#
    3002	Horiba
    Spectrofluorometer
	HB#
    1894	GE
    Refrigerator/Freezer
	HB#
    3430	Centromix
    Microcentrifuge
	HB#
    3438	Pharmacia
    Electrophoresis Power Supply
	HB#
    3185	Invitrogen
    Electrophoresis Power Supply
	HB#
    1507	Thermolyne
    Heating Block
	HB#
    1800	Thermolyne
    Heating Block
	HB#
    3067	Fisher
    Scientific Heating Block
	HB#
    1908	Bio
    Rad Electrophoresis Power Supply
	HB#
    3432	Bio
    Rad Electrophoresis Power Supply
	HB#
    2289	Benchmark
    Shaker
	HB#
    3433	Labline
    Plate Rotator
	Computer
    #46	Dell
    computer for Horiba Spectrofluorometer
	 	 







	RM
    #130	Equipment
    Description
	HB#
    2174	Ludlum
    Geiger Counter
	HB#
    3350	Ludlum
    Geiger Counter
	HB#
    1593	Fume
    Hood
	 	 
	RM#131	Equipment
    Description
	HB#
    2005	Sorvall
    Centrifuge
	N/A	Controlled
    Environment Incubator Shaker
	HB#
    3300	GE
    Freezer
	HB#
    1891	Admiral
    Double door Refrigerator
	 	 
	Polymer
    Manufacturing	Equipment
    Description
	HB#
    3317	Thermo
    Scientific Liquid Nitrogen Tank




 




    	B1-4



    	 



    

 


Administrative
Offices (Inventory List)


 


	 	● 	Front
    Office Conf. Rm- Chairs-7, Desk-1, Phone-1, Chalkboard-1 Table-1
	 	●	Front
    Rec Area - Chairs-3, Desk-1, Phone-1 , File Cabinets-2, Scanner-1/(Fujitsu), Monitor-1, Laptop-1/(#LT-02), Shredder-1/(Fellowes),
    Glass Table-1
	 	● 	Open
    Area Chairs-3, Desk-1 (with 2 corner extensions), Printer-1/(Sharp MX-624ON), Shredmaster-1/(6550X), File Cabinets-5, Bulletin
    Boards-2, Monitors-3, Computers-3 (#76, # 12, no #)
	 	● 	Open
    Area/Back) File Cabinet-1, Mail slots/For employees/(Large) 
	 	●	Rm
    107 Chairs-2, Desks-2, Monitors-3, Computer-1 (#15), Laptops-2 (#lt-07), (Laptop #36), File Cabinets-2
	 	●	Rm-104
    Chairs-2, Desks-2, Monitors-2, Computer-1(#16), Laptop-1(#93), Phones-2, File Cabinets-2, DVD Player/(Samsung), Laminating
    Machine-1 (Royal Sovereign)
	 	●	Rm-108
    File Cabinets-7
	 	●	Rm-114
    File Cabinets-28
	 	●	Rm-115
    File Cabinets-15
	 	●	Rm-117
    Chairs-2, Desks-3, Monitor-1, Laptop-1/(#79), Phone-1, File Cabinets-2
	 	●	Rm-118
    Chairs-2, Desks-2, Computer-1(#35), File Cabinet-1, Phone-1, Bulletin Board-1
	 	● 	Rm-119
    Chairs-2, Desk-1(with 2 corner extensions), File Cabinets-2, Monitor-1, Laptops-3/Computer #73, (no #’s for the other
    2, Phone-1
	 	● 	Rm-120
    Chairs-2, Desk-1 (with 2 corner extensions), Monitor-1, Laptop-1/(computer# 69), File Cabinet-1 Phone-1
	 	● 	Rm-121
    Chairs-2, Desk-1 (with 2 corner extensions), Phone-1, File Cabinets-2, Monitor-1, Computer-1 (#14) Printer-1 (MFC-8480DN)
	 	● 	Rm-122
    Chairs-2, Desk-1(with -2 corner extensions), Phone-1, Printer-1, Monitor-1 Laptop(no #)
	 	● 	Rm-205
    Chairs-2, Desk-1(with 2 corner extensions) Phone-1, File Cabinets-3, Monitor-1, Printer-1
	 	● 	Rm-206
    Chairs-2, Desk-1 (with 2 corner extensions) Phone-1 File Cabinets-2, Monitor-1, Laptop-1, Printer-1, Bulletin Boards-2 , Small
    cart-1
	 	● 	Rm-207
    Chairs-2, Desk-1 (with 2 corner extensions) Phone-1 File Cabinets-3, Monitor-1, Laptop-1,(Computer #78)
	 	● 	Rm-208
    Chairs-5, Desk-1, Table-1, Phone-1, File Cabinets-1, Monitor-1, Laptop-1,(no #), Printer-1
	 	● 	Rm-209
    Chairs-3, Desk-1, File Cabinets-3, Cart-1, Phone-1, Monitor-1, Laptop-1(Computer #29), Bulletin Board-1
	 	● 	Rm-214
    Chairs-7, Desks-2, Table-1, Phone-1
	 	● 	Upstairs
    Conf Area/Open.......Chairs-8, Table-1, File Cabinets-8, Phone-2/(wall mounted), Lockers-18
	 	● 	Upstairs
    Conf Rm-502 Chairs-17, Table-3/(1 Large/2 Small), Sofa-1, File Cabinets-3, Polycom-1, Printer-1/(Brother MFC-9460CDN), Flatscreen
    TV,(Panasonic)-1, Presentation Board-1, Large Chalkboard-1, Bullentin Board-1, Extra Cabinets-2/wood
	 	● 	Rm-503-
    Chairs-6, Table-1, Sharp TV-1, Large Cart-1, Presentation Board/Chalkboard-1, Bulletin Board-1
	 	● 	Boiler
    Area Chair-1, Desk-1, File Cabinet-1, Phone-1, Monitor-1, Laptop-1(no #),
	 	● 	Rm-604
    Chairs-3, Desks-3, Monitors-4, Phone-1, File Cabinets-2, Laptops-2/(no #’s), Computer-1(#13), Bulletin Board-1
	 	● 	Rm-605
    Chairs-3, Desks-2, Phone-2, FileCabinet-1,Computer-1(no #), Laptop-1(no #)
	 	● 	Rm-606
    Printer-2/(Hp Officejet 7310,), (Ricoh SPC410DN)/ Monitors-4, Phone-1, Laptops-2/(#40/no # for other laptop), Computer-8 (#42,
    #11, #61,#22, #37, #25, #31,/no # )
	 	● 	Rm-607
    Desk-1, Phone-1, Bulletin Boards-3, Printer-1/(Hewlett Packard Design Jet 750C Plus Plotter
	 	● 	Rm
    608 Desk-1, Phone-1, Chairs-3, Bulletin Boards-2, mail slots-2/small
	 	● 	 Rm-609
    Desks-2, Chairs-2, File Cabinets-3, Laptops-3(computer # 21/no # for the other 2), Computer-10 (#33, #60, #26, #30, #22, #10,
    #9, #28, #8, #27), Servers-6
	 	● 	Rm-610
    Chairs-3, Desks-2, Phone-1, File Cabinets-4,Monitors-2, Bulletin boards-2, Laptop-1(no #)
	 	● 	Rm-611
    Chairs-10, Desk-1, Bulletin boards-2, Phone-1 File cabinets-2, Laptops-3/(computer# 26/no #’s for the other 2)
	 	● 	Rm
    -612 Chairs-4, Desk-1, Phone-1, File Cabinets-4, Bulletin board-1
	 	● 	Rm-613
    Chairs-2, Desk-1, File cabinets-6, Phones-2, Printer-1(Hp), Laminating Machine/(Epson 4490 Photo Perfection, Monitors-11,
    Computer-12 (#17, #7, #77, #75,#2, #19, #3., #4/the other 4 no #’s)


 




    	B1-5



    	 



    

 


 





 




    	B1-6



    	 



    

 





 




    	B1-7



    	 



    

 


EXHIBIT
B-3


 


FORM
OF SELLER LEASE


 


[Attached]