Page 2 of 12

(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons (also referred to herein as Alkyl Alcohol Alkoxylates or AAA) C >14 , ethoxylated ( CAS Reg. No. 251553 - 55 - 6 ) in pesticide formulations acts as a dispersant, an emulsifier, a solvent or as a surfactant. The registrant requests the exemption with no limitation as to the concentration of the material in final pesticide formulations. The purpose of this document is to assess, as required under the Federal Food Drug and Cosmetic Act (FFDCA), the risk of the use of an additional CAS Reg. No. as an inert ingredient in pesticide products and is based on previous assessments for AAAs along with a rationale provided by the petitioner as to why the additional CAS Reg. No. can be considered safe under the existing tolerance exemption descriptors for AAA . The petition contends that alcohols C >14 , ethoxylated ( CAS Reg. No. 251553 - 55 - 6 ) is structurally similar to the group Alkyl Alcohol Alkoxylates (AAA) previously reviewed in the Agency ’s risk assessment (Davis et al . 1993) . Specificall y, the contention is that CAS Reg. No . 251553 - 55 - 6 meets the chemical identity ɑ- alkyl - ω - hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers where the alkyl chain contains a minimum of six carbons. According to the petition , the degree of alkoxylation for the petitioned substance c an vary in number average molecular weight from a range of approximately 591 to 5,513. In cases where the minimum number average molecular weight is 1,100 or more, the petition’s basis for support for establishment of an exemption from the requirement of tolerance under 40 CFR §180.960 is that AAAs with high molecular weights meet the criteria for a low - risk polymer as defined under 40 CFR § 723.250. Further, for the remaining AAAs, those with lower molecular weights between 591 and 1,100, the petition se eks to establish tolerance exemptions for all AAAs under 40 CFR § 180.910, 180.930 and 180.940(a). The petition suggests that for the higher molecular weight polymers that would fall under 180.960, there are no risk concerns since molecules of such high molecular weight are not likely to be absorbed significantly by any route of exposure that is reasonably foreseeable. Thus it is posited that there is low concern for potential hazards to the general population or for infants and children. For the lower molecular weight AAA’s that would fall under 40 CFR § 180.910, 180.930 and 180.940(a) , the registrant is relying upon the Agency’s previous review of the AAAs as noted earlier. The petitioner has been granted permission by the data owner(s) to cite MRIDs 47067001, 47676801, 47050602, 47676803, and 47676802 in support of the proposed request for the exemption from the requirements of a tolerance. The Agency has reviewed the petitioner’s claim that the addition of the requested CAS Reg. No. is acceptable under the current tolerance exemption descriptors for AAA. . The CITAB has confirmed that the requested CAS Reg. No. is appropriately added to the currently approved descriptors and that no further review is required. The requested CAS Reg. No. does con sist of compounds that meets the chemical identity ɑ- alkyl - ω - hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers where the alkyl chain contains a minimum of six carbons.Page 3 of 12

The Agency has determined that the proposed addition of the requested CAS Reg. No. is adequately supported by the existing data and assessment and that no additional data or review is required. Inclusion of the additional chemicals described above in the risk assessments for ɑ- alkyl - ω - hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers would in no way alter the prior risk assessments given the generic findings on toxicity and the worst case exposure assumptions used in those risk assessments. Accordingly, based on the findings in the earlier rules, EPA has determined that there is a reasonable certainty that no harm to any p opulation subgroup, including infants and children, will result from aggregate exposure to ɑalkyl - ω - hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers by including the additional chemical described above, under reasonably foreseeable circumstances. Therefore, the amendment of an exemption from the requirements of a tolerance under 4 0 CFR 180. 910, 180.930, 180.940(a) and 180.960 is approved on the bases where the minimum number average molecular weight is 1,100 or more, qualifies for exemption under 40 CFR §180.960 and that the remaining AAAs, those with lower molecular weights betwe en 591 and 1,100, would qualify under 40 CFR § 180.910, 180.930 and 180.940(a). Based upon the information summarized above from the Agency’s previous assessment s , the Agency approves of the request to amend an existing tolerance exemption descriptor for ɑ- alkyl - ω hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers by adding one CAS Reg. No. (251553 - 55 - 6 for alcohols, C > 14 , ethoxylated) to a grouping of closely related substances with associated CAS Reg. Nos. rather than to a single chemical entity. Therefore the regulatory text associated with the tolerance exemption for α - alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers under 40 CFR 180.910 and 930 will be revised to read as follows:

Inert ingredients Limits Uses α- alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers where the alkyl chain contains a minimum of six carbons (CAS Reg. Nos.: 9002 - 92 - 0; 9004 - 95 - 9; 9004 - 98 - 2; 9005 - 00 - 9; 9035 - 85 - 2; 9038 - 29 - 3; 9038 - 43 - 1; 9040 - 05 - 5; 9043 - 30 - 5; 9087 - 53 - 0; 2519 0 - 05 - 0; 24938 - 91 - 8; 25231 - 21 - 4; 251553 - 55 - 6; 26183 - 52 - 8; 26468 - 86 - 0; 26636 - 39 - 5; 27252 - 75 - 1; 27306 - 79 - 2; 31726 - 34 - 8; 34398 - 01 - 1; 34398 - 05 - 5; 37251 - 67 - 5; 37311 - 00 - 5; 37311 - 01 - 6; 37311 - 02 - 7; 37311 - 04 - 9; 39587 - 22 - 9; 50861 - 66 - 0; 52232 - 09 - 4; 52292 - 17 - 8; 52609 - 1 9 - 5; 57679 - 21 - 7; 59112 - 62 - 8; 60828 - 78 - 6; 61702 - 78 - 1; 61725 - 89 - 1; 61791 - 13 - 7; 61791 - 20 - 6; 61791 - 28 - 4; 61804 - 34 - 0; 61827 - 42 - 7; 61827 - 84 - 7; 62648 - 50 - 4; 63303 - 01 - 5; 63658 - 45 - 7; 63793 - 60 - 2; 64366 - 70 - 7; 64415 - Surfactants, related adjuvants of surfactantsPage 4 of 12

24 - 3; 64415 - 25 - 4; 64425 - 86 - 1; 65104 - 72 - 5; 65150 - 81 - 4; 66455 - 14 - 9: 66455 - 15 - 0; 67254 - 71 - 1; 67763 - 08 - 0; 68002 - 96 - 0; 68002 - 97 - 1; 68131 - 39 - 5; 68131 - 40 - 8; 68154 - 96 - 1; 68154 - 97 - 2; 68154 - 98 - 3; 68155 - 01 - 1; 68213 - 23 - 0; 68213 - 24 - 1; 68238 - 81 - 3; 68238 - 82 - 4; 68409 - 58 - 5; 68409 - 59 - 6; 68439 - 30 - 5; 68439 - 45 - 2; 68439 - 46 - 3; 684 39 - 48 - 5; 68439 - 49 - 6; 68439 - 50 - 9; 68439 - 51 - 0; 68439 - 53 - 2; 68439 - 54 - 3; 68458 - 88 - 8; 68526 - 94 - 3; 68526 - 95 - 4; 68551 - 12 - 2; 68551 - 13 - 3; 68551 - 14 - 4; 68603 - 20 - 3; 68603 - 25 - 8; 68920 - 66 - 1; 68920 - 69 - 4; 68937 - 66 - 6; 68951 - 67 - 7; 68954 - 94 - 9; 68987 - 81 - 5; 68991 - 48 - 0; 69011 - 3 6 - 5; 69013 - 18 - 9; 69013 - 19 - 0; 69227 - 20 - 9; 69227 - 21 - 0; 69227 - 22 - 1; 69364 - 63 - 2; 70750 - 27 - 5; 70879 - 83 - 3; 70955 - 07 - 6; 71011 - 10 - 4; 71060 - 57 - 6; 71243 - 46 - 4; 72066 - 65 - 0; 72108 - 90 - 8; 72484 - 69 - 6; 72854 - 13 - 8; 72905 - 87 - 4; 73018 - 31 - 2; 73049 - 34 - 0; 74432 - 13 - 6; 74499 - 34 - 6; 78330 - 19 - 5; 78330 - 20 - 8; 78330 - 21 - 9; 78330 - 23 - 1; 79771 - 03 - 2; 84133 - 50 - 6; 85422 - 93 - 1; 97043 - 91 - 9; 97953 - 22 - 5; 102782 - 43 - 4; 103331 - 86 - 8; 103657 - 84 - 7; 103657 - 85 - 8; 103818 - 93 - 5; 103819 - 03 - 0; 106232 - 83 - 1; 111905 - 54 - 5; 116810 - 31 - 2; 116810 - 32 - 3; 116810 - 33 - 4; 1203 13 - 48 - 6; 120944 - 68 - 5; 121617 - 09 - 2; 126646 - 02 - 4; 126950 - 62 - 7; 127036 - 24 - 2; 139626 - 71 - 4; 152231 - 44 - 2; 154518 - 36 - 2; 157627 - 86 - 6; 157627 - 88 - 8; 157707 - 41 - 0; 157707 - 43 - 2; 159653 - 49 - 3; 160875 - 66 - 1; 160901 - 20 - 2; 160901 - 09 - 7; 160901 - 19 - 9; 161025 - 21 - 4; 161025 - 22 - 5; 166736 - 08 - 9; 169107 - 21 - 5; 172588 - 43 - 1; 176022 - 76 - 7; 196823 - 11 - 7; 287935 - 46 - 0; 288260 - 45 - 7; 303176 - 75 - 2; 954108 - 36 - 2) The regulatory text associated with the tolerance exemption for α - alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers under 40 CFR 180.940(a) will be revised to read as follows:

Pesticide Chemical CAS Reg. No Limits α- alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers where the alkyl 9002 - 92 - 0; 9004 - 95 - 9; 9004 - 98 - 2;Page 5 of 12

chain contains a minimum of six carbons ( CAS Reg. No 251553 - 55 - 6) 9005 - 00 - 9; 9035 - 85 - 2; 9038 - 29 - 3; 9038 - 43 - 1; 9040 - 05 - 5; 9043 - 30 - 5; 9087 - 53 - 0; 25190 - 05 - 0; 24938 - 91 - 8; 25231 - 21 - 4; 251553 - 55 - 6; 26183 - 52 - 8; 26468 - 86 - 0; 266 36 - 39 - 5; 27252 - 75 - 1; 27306 - 79 - 2; 31726 - 34 - 8; 34398 - 01 - 1; 34398 - 05 - 5; 37251 - 67 - 5; 37311 - 00 - 5; 37311 - 01 - 6; 37311 - 02 - 7; 37311 - 04 - 9; 39587 - 22 - 9; 50861 - 66 - 0; 52232 - 09 - 4; 52292 - 17 - 8; 52609 - 19 - 5; 57679 - 21 - 7; 59112 - 62 - 8; 60828 - 78 - 6; 61702 - 78 - 1; 61725 - 89 - 1; 61791 - 1 3 - 7; 61791 - 20 - 6; 61791 - 28 - 4; 61804 - 34 - 0; 61827 - 42 - 7; 61827 - 84 - 7; 62648 - 50 - 4; 63303 - 01 - 5; 63658 - 45 - 7; 63793 - 60 - 2; 64366 - 70 - 7; 64415 - 24 - 3; 64415 - 25 - 4; 64425 - 86 - 1;Page 6 of 12 65104 - 72 - 5; 65150 - 81 - 4; 66455 - 14 - 9: 66455 - 15 - 0; 67254 - 71 - 1; 67763 - 08 - 0; 68002 - 96 - 0; 68002 - 97 - 1; 68131 - 39 - 5; 68131 - 40 - 8; 68154 - 96 - 1; 68154 - 97 - 2; 68154 - 98 - 3; 68155 - 01 - 1; 68213 - 23 - 0; 68213 - 24 - 1; 68238 - 81 - 3; 68238 - 82 - 4; 68409 - 58 - 5; 68409 - 59 - 6; 68439 - 30 - 5; 68439 - 45 - 2; 68439 - 46 - 3; 68439 - 48 - 5; 68439 - 49 - 6; 68439 - 50 - 9; 68439 - 51 - 0; 68439 - 53 - 2; 68439 - 54 - 3; 684 58 - 88 - 8; 68526 - 94 - 3; 68526 - 95 - 4; 68551 - 12 - 2; 68551 - 13 - 3; 68551 - 14 - 4; 68603 - 20 - 3; 68603 - 25 - 8; 68920 - 66 - 1; 68920 - 69 - 4; 68937 - 66 - 6; 68951 - 67 - 7; 68954 - 94 - 9; 68987 - 81 - 5; 68991 - 48 - 0; 69011 - 36 - 5; 69013 - 18 - 9;Page 7 of 12 69013 - 19 - 0; 69227 - 20 - 9; 69227 - 21 - 0; 69227 - 22 - 1; 69364 - 6 3 - 2; 70750 - 27 - 5; 70879 - 83 - 3; 70955 - 07 - 6; 71011 - 10 - 4; 71060 - 57 - 6; 71243 - 46 - 4; 72066 - 65 - 0; 72108 - 90 - 8; 72484 - 69 - 6; 72854 - 13 - 8; 72905 - 87 - 4; 73018 - 31 - 2; 73049 - 34 - 0; 74432 - 13 - 6; 74499 - 34 - 6; 78330 - 19 - 5; 78330 - 20 - 8; 78330 - 21 - 9; 78330 - 23 - 1; 79771 - 03 - 2; 84133 - 50 - 6; 85422 - 93 - 1; 97043 - 91 - 9; 97953 - 22 - 5; 102782 - 43 - 4; 103331 - 86 - 8; 103657 - 84 - 7; 103657 - 85 - 8; 103818 - 93 - 5; 103819 - 03 - 0; 106232 - 83 - 1; 111905 - 54 - 5; 116810 - 31 - 2; 116810 - 32 - 3; 116810 - 33 - 4; 120313 - 48 - 6; 120944 - 68 - 5; 121617 - 09 - 2; 126646 - 02 - 4; 126950 - 62 - 7; 127036 - 24 - 2 ;Page 8 of 12 139626 - 71 - 4; 152231 - 44 - 2; 154518 - 36 - 2; 157627 - 86 - 6; 157627 - 88 - 8; 157707 - 41 - 0; 157707 - 43 - 2; 159653 - 49 - 3; 160875 - 66 - 1; 160901 - 20 - 2; 160901 - 09 - 7; 160901 - 19 - 9; 161025 - 21 - 4; 1 61025 - 22 - 5; 166736 - 08 - 9; 169107 - 21 - 5; 172588 - 43 - 1; 176022 - 76 - 7; 196823 - 11 - 7; 287935 - 46 - 0; 288260 - 45 - 7; 303176 - 75 - 2; 954108 - 36 - 2 The regulatory text associated with the tolerance exemption for α - alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene ) polymers under 40 CFR 180.960 will be revised to read as follows: Polymer CAS No. α- alkyl - ω -hydroxypoly (oxypropylene) and/or poly (oxyethylene) polymers where the alkyl chain contains a minimum of six carbons and a minimum number average molecular we ight (in amu) 1,100 9002 - 92 - 0; 9004 - 95 - 9; 9004 - 98 - 2; 9005 - 00 - 9; 9035 - 85 - 2; 9038 - 29 - 3; 9038 - 43 - 1; 9040 - 05 - 5; 9043 - 30 - 5; 9087 - 53 - 0; 25190 - 05 - 0; 24938 - 91 - 8; 25231 - 21 - 4; 251553 - 55 - 6; 26183 - 52 - 8; 26468 - 86 - 0; 26636 - 39 - 5; 27252 - 75 - 1; 27306 - 79 - 2; 31726 - 34 - 8; 34398 - 01 - 1; 34398 - 05 - 5; 37251 - 67 - 5; 37311 - 00 - 5; 37311 - 01 - 6; 37311 - 02 - 7; 37311 - 04 - 9;Page 9 of 12 39587 - 22 - 9; 50861 - 66 - 0; 52232 - 09 - 4; 52292 - 17 - 8; 52609 - 19 - 5; 57679 - 21 - 7; 59112 - 62 - 8; 60828 - 78 - 6; 61702 - 78 - 1; 61725 - 89 - 1; 61791 - 13 - 7; 61791 - 20 - 6; 61791 - 28 - 4; 61804 - 34 - 0; 61827 - 42 - 7; 61827 - 84 - 7; 62648 - 50 - 4; 63303 - 01 - 5; 63658 - 45 - 7; 63793 - 60 - 2; 64366 - 70 - 7; 64415 - 24 - 3; 64415 - 25 - 4; 64425 - 86 - 1; 65104 - 72 - 5; 65150 - 81 - 4; 66455 - 14 - 9: 66455 - 15 - 0; 67254 - 71 - 1; 67763 - 08 - 0; 68002 - 96 - 0; 68002 - 97 - 1; 68131 - 39 - 5; 68131 - 40 - 8; 68154 - 96 - 1; 68154 - 97 - 2; 6 8154 - 98 - 3; 68155 - 01 - 1; 68213 - 23 - 0; 68213 - 24 - 1; 68238 - 81 - 3; 68238 - 82 - 4; 68409 - 58 - 5; 68409 - 59 - 6; 68439 - 30 - 5; 68439 - 45 - 2; 68439 - 46 - 3; 68439 - 48 - 5; 68439 - 49 - 6; 68439 - 50 - 9; 68439 - 51 - 0; 68439 - 53 - 2; 68439 - 54 - 3; 68458 - 88 - 8; 68526 - 94 - 3; 68526 - 95 - 4; 68551 - 12 - 2; 68551 - 13 - 3; 68551 - 14 - 4; 68603 - 20 - 3; 68603 - 25 - 8; 68920 - 66 - 1; 68920 - 69 - 4; 68937 - 66 - 6; 68951 - 67 - 7; 68954 - 94 - 9; 68987 - 81 - 5; 68991 - 48 - 0; 69011 - 36 - 5; 69013 - 18 - 9; 69013 - 19 - 0; 69227 - 20 - 9; 69227 - 21 - 0; 69227 - 22 - 1; 69364 - 63 - 2; 70750 - 27 - 5; 70879 - 83 - 3; 70955 - 07 - 6; 71011 - 10 - 4; 71060 - 57 - 6; 71243 - 46 - 4; 72066 - 65 - 0; 72108 - 90 - 8; 72484 - 69 - 6; 72854 - 13 - 8; 72905 - 87 - 4; 73018 - 31 - 2; 73049 - 34 - 0; 74432 - 13 - 6; 74499 - 34 - 6; 78330 - 19 - 5; 78330 - 20 - 8;Page 10 of 12 78330 - 21 - 9; 78330 - 23 - 1; 79771 - 03 - 2; 84133 - 50 - 6; 85422 - 93 - 1; 97043 - 91 - 9; 97953 - 22 - 5; 102782 - 43 - 4; 103331 - 86 - 8; 103657 - 84 - 7; 103657 - 85 - 8; 103818 - 93 - 5; 103819 - 03 - 0; 106232 - 83 - 1; 111905 - 54 - 5; 116810 - 31 - 2; 116810 - 32 - 3; 116810 - 33 - 4; 120313 - 48 - 6; 120944 - 68 - 5; 121617 - 09 - 2; 126646 - 02 - 4; 126950 - 62 - 7; 127036 - 24 - 2; 139626 - 71 - 4; 152231 - 44 - 2; 154518 - 36 - 2; 157627 - 86 - 6; 157627 - 88 - 8; 157707 - 41 - 0; 157707 - 43 - 2; 159653 - 49 - 3; 160875 - 66 - 1; 160901 - 20 - 2; 160901 - 09 - 7; 160901 - 19 - 9; 161025 - 21 - 4; 161025 - 22 - 5; 166736 - 08 - 9; 169107 - 21 - 5; 172588 - 43 - 1; 176022 - 76 - 7; 196823 - 11 - 7; 287935 - 46 - 0; 288260 - 45 - 7; 303176 - 75 - 2; 954108 - 36 - 2Page 11 of 12

Reference Davis, D., B - H. Chin, A. LaMay, M. Lloyd, C. Olinger, S. Piper. 2009. Alkyl Alcohol Alkoxylate Phosphate and Sulfate Derivatives (AAAPDs and AAASDs

– JITF CST 2 Inert Ingredients). Human Health Assessment to S upport Proposed Exemption from the Requirement of a Tolerance When Used as Inert Ingredients in Pesticide Formulations. CASRN 9046 - 01 - 9. PC Code 911339. Unpublished Memorandum 8 June 2009 to K. Leifer U.S. EPA.

RDI: PV Shah, K. Leifer M.I.Dow:S7 958 :PY1:(703)305 - 5533: IIAB:7505PPage 12 of 12