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SECURITIES AND EXCHANGE COMMISSION
 Washington, D.C. 20549
 FORM 11-K
  þ
    
    ANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 For the fiscal year ended December 31, 2010
 OR
 o
    
    TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 For the transition period from  to
 Commission file number 000-14902
 A.
    
    Full title of the plan and the address of the plan, if different from
that of the issuer named below:
 Meridian Bioscience, Inc.
 Savings and Investment Plan
 B.
    
    Name of issuer of the securities held pursuant to the plan and the
address of its principal executive office:
 Meridian Bioscience, Inc.
 3471 River Hills Drive
Cincinnati, OH 45241




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Meridian Bioscience, Inc. Savings and Investment Plan
 Financial Statements
 As of December 31, 2010 and 2009 and for the year ended December 31, 2010
 Contents
 Report of Independent Registered Public Accounting Firm
    
    
    1Financial Statements:Statements of Net Assets Available for Benefits
    
    
    2Statement of Changes in Net Assets Available for Benefits
    
    
    3Notes to Financial Statements
    
    
    4Supplemental Schedules:Schedule of Assets (Held At End of Year)
    
    
    14Signature
    
    
    15Exhibits
    
    
    16EX-23.1




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1




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Meridian Bioscience, Inc. Savings and Investment Plan
 
 STATEMENTS OF NET ASSETS AVAILABLE FOR BENEFITS
  ASSETS
    
    2010
    
    
    2009Cash
    
    $
    298
    
    
    $
    297Investments, at fair value:Common stock
    
    
    137,729
    
    
    
    105,547Registered mutual funds
    
    
    22,299,944
    
    
    
    18,898,910Collective trust
    
    
    3,309,033
    
    
    
    2,824,691Total investments
    
    
    25,746,706
    
    
    
    21,829,148Receivables:Employer contributions
    
    
    614,913
    
    
    
    588,764Notes receivable from participants
    
    
    645,375
    
    
    
    424,666Total receivables
    
    
    1,260,288
    
    
    
    1,013,430Total assets
    
    
    27,007,292
    
    
    
    22,842,875Excess contributions payable
    
    
    (94,648
    )
    
    
    (132,910
    )Net assets available for
benefits, at fair value
    
    
    26,912,644
    
    
    
    22,709,965Adjustment from fair value to
contract value for interest in
the collective trust relating to
fully benefit-responsive
investment contracts
    
    
    
    
    
    
    204,900Net assets available for benefits
    
    $
    26,912,644
    
    
    $
    22,914,865
   2




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Meridian Bioscience, Inc. Savings and Investment Plan
 
 STATEMENT OF CHANGES IN NET ASSETS AVAILABLE FOR BENEFITS
  Additions to net assets attributed to:Net appreciation in fair value of investments
    
    $
    2,264,062Dividend and interest income
    
    
    511,422Participant contributions
    
    
    1,672,472Employer contributions
    
    
    1,203,742Rollover contributions
    
    
    58,081Interest income on notes receivable from participants
    
    
    27,516Total additions
    
    
    5,737,295Deductions from net assets attributed to:Benefit payments
    
    
    1,732,756Administrative expenses
    
    
    6,760Total deductions
    
    
    1,739,516Net increase
    
    
    3,997,779Net assets available for benefits:Beginning of year
    
    
    22,914,865End of year
    
    $
    26,912,644
   3




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NOTES TO FINANCIAL STATEMENTS  Meridian Bioscience, Inc. Savings and Investment Plan
 NOTE A  DESCRIPTION OF PLAN
  General
  Participation
  Trustee
  Contributions
  Participant Accounts
   4




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NOTE A  DESCRIPTION OF PLAN
 Vesting
  Years of Service
    
    Vesting PercentageLess than 1 year
    
    
    0
    %1 year
    
    
    20
    %2 years
    
    
    40
    %3 years
    
    
    60
    %4 years
    
    
    80
    %5 years
    
    
    100
    %
 Notes Receivable from Participants
  Payment of Benefits
  Expenses of the Plan
  Forfeitures
   5




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NOTE A  DESCRIPTION OF PLAN
 Investment Options
   NOTE B  SIGNIFICANT ACCOUNTING POLICIES
 Basis of Accounting
  Use of Estimates
  Investment Valuation and Income Reporting
   Notes Receivable from Participants
  Payment of Benefits
   6




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NOTE B  SIGNIFICANT ACCOUNTING POLICIES
 Risks and Uncertainties
  Fully Benefit-Responsive Investment Contracts held in Collective Trust
      7




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NOTE B  SIGNIFICANT ACCOUNTING POLICIES
 Recent Accounting Pronouncements
 Improving
Disclosures about Fair Value Measurements
 Reporting Loans to
Participants by Defined Contribution Pension Plans
 Amendments to Achieve
Common Fair Value Measurement and Disclosure Requirements in U.S. GAAP and IFRSs.
  8




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NOTE C  INVESTMENTS
  2010
    
    
    2009ML Retirement Preservation Trust**
    
    $
    3,309,033
    
    
    $
    3,029,591American Funds Washington Mutual Investors Fund
    
    
    2,961,435
    
    
    
    3,094,223Columbia Acorn Fund
    
    
    2,568,379
    
    
    
    Blackrock Basic Value Fund
    
    
    2,489,142
    
    
    
    2,336,017American Funds Euro Pacific Growth Fund
    
    
    2,435,158
    
    
    
    2,217,053Blackrock S&P 500 Index Fund
    
    
    2,181,272
    
    
    
    PIMCO Total Return Fund
    
    
    2,045,945
    
    
    
    1,320,001Blackrock Small/Mid Cap Growth Equity Portfolio
    
    
    1,751,876
    
    
    
    1,351,784American Century Diversified Bond Fund
    
    
    1,425,058
    
    
    
    Blackrock Value Opportunities Fund
    
    
    
    
    
    
    1,990,519Allianz CCM Capital Appreciation Fund
    
    
    
    
    
    
    1,766,177American Funds Bond Fund of America
    
    
    
    
    
    
    1,268,531
 **
    
    The fair values of the fund were $3,309,033 and $2,824,691 at December 31, 2010 and 2009,
respectively.  Common stock
    
    $
    11,104Registered mutual funds
    
    
    2,252,958$
    2,264,062
 NOTE D  TAX STATUS
  NOTE E  PRIORITIES UPON TERMINATION OF THE PLAN
   9




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NOTE F  PARTY-IN-INTEREST TRANSACTIONS
  NOTE G  FAIR VALUE MEASUREMENTS
       Common stock/mutual funds
 Collective trust
  10




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NOTE G  FAIR VALUE MEASUREMENTS
   Level 1
    
    
    Level 2
    
    
    Level 3
    
    
    TotalCompany common stock
    
    $
    137,729
    
    
    $
    
    
    
    $
    
    
    
    $
    137,729Mutual funds:Capital growth funds
    
    
    17,451,962
    
    
    
    
    
    
    
    
    
    
    
    17,451,962Balanced funds
    
    
    2,520,958
    
    
    
    
    
    
    
    
    
    
    
    2,520,958Income funds
    
    
    1,943,037
    
    
    
    
    
    
    
    
    
    
    
    1,943,037Other funds
    
    
    383,987
    
    
    
    
    
    
    
    
    
    
    
    383,987Collective trust  short term bond
fund
    
    
    
    
    
    
    3,309,033
    
    
    
    
    
    
    
    3,309,033Total assets at fair value
    
    $
    22,437,673
    
    
    $
    3,309,033
    
    
    $
    
    
    
    $
    25,746,706
  Level 1
    
    
    Level 2
    
    
    Level 3
    
    
    TotalCompany common stock
    
    $
    105,547
    
    
    $
    
    
    
    $
    
    
    
    $
    105,547Mutual funds:Capital growth funds
    
    
    15,205,288
    
    
    
    
    
    
    
    
    
    
    
    15,205,288Balanced funds
    
    
    1,717,658
    
    
    
    
    
    
    
    
    
    
    
    1,717,658Income funds
    
    
    1,552,888
    
    
    
    
    
    
    
    
    
    
    
    1,552,888Other funds
    
    
    423,076
    
    
    
    
    
    
    
    
    
    
    
    423,076Collective trust  stable value fund
    
    
    
    
    
    
    2,824,691
    
    
    
    
    
    
    
    2,824,691Total assets at fair value
    
    $
    19,004,457
    
    
    $
    2,824,691
    
    
    $
    
    
    
    $
    21,829,148
 Fair Value
Measurements and Disclosures
  11




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NOTE H  RECONCILIATION TO FORM 5500
   Net assets available for benefits per the financial statements
    
    $
    22,914,865Less: Adjustment from contract value to fair value for fully
benefit-responsive investment contracts
    
    
    (204,900
    )Net assets available for benefits per the Form 5500
    
    $
    22,709,965
  Total additions per the financial statements
    
    $
    5,737,295Add: Excess contributions payable
    
    
    94,648Add: 2009 Adjustment from contract value to fair value for fully
benefit-responsive investment contracts
    
    
    204,900Total income per the Form 5500
    
    $
    6,036,843
  Total deductions per the financial statements
    
    $
    1,739,516Add: Classification of corrective distributions
    
    
    94,648Total deductions per the Form 5500
    
    $
    1,834,164
 NOTE I  SUBSEQUENT EVENT
    12




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SUPPLEMENTAL INFORMATION
  13




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Meridian Bioscience, Inc. Savings and Investment Plan
EIN 31-0888197 Plan No 001
 FORM 5500, SCHEDULE H, PART IV, LINE 4i-
 
 SCHEDULE OF ASSETS (HELD AT END OF YEAR)
December 31, 2010
 (b)Description ofinvestmentincludingmaturity date,(a)
    
    rate of interest,Identity of issuer, borrower, lessor, or
    
    collateral, par or
    
    
    (c)
    
    
    (d)similar party
    
    maturity value
    
    
    Cost
    
    
    Current valueRegistered Mutual FundsAmerican Century Diversified Bond Fund
    
    132,439 shares
    
    
    **
    
    
    $
    1,425,058American Funds Balanced Fund
    
    26,596 shares
    
    
    **
    
    
    
    475,013American Funds Euro Pacific Growth Fund
    
    59,935 shares
    
    
    **
    
    
    
    2,435,158American Funds Growth Fund of America
    
    21,963 shares
    
    
    **
    
    
    
    658,438American Funds Washington Mutual Investors Fund
    
    109,440 shares
    
    
    **
    
    
    
    2,961,435* Blackrock Basic Value Fund
    
    97,270 shares
    
    
    **
    
    
    
    2,489,142* Blackrock Global Allocation Fund
    
    19,773 shares
    
    
    **
    
    
    
    383,987* Blackrock Small/Mid Cap Growth Equity Portfolio
    
    142,661 shares
    
    
    **
    
    
    
    1,751,876* Blackrock S&P 500 Index Fund
    
    141,825 shares
    
    
    **
    
    
    
    2,181,272Columbia Acorn Fund
    
    87,838 shares
    
    
    **
    
    
    
    2,568,379Delaware Emerging Markets Fund
    
    38,710 shares
    
    
    **
    
    
    
    619,751Eaton Vance Income Fund of Boston
    
    52,234 shares
    
    
    **
    
    
    
    305,048Janus Adviser Forty Fund
    
    14,896 shares
    
    
    **
    
    
    
    502,581Perkins Small Cap Value Fund
    
    22,948 shares
    
    
    **
    
    
    
    549,596PIMCO Commodity Real Return Strategy Fund
    
    23,246 shares
    
    
    **
    
    
    
    212,931PIMCO Total Return Fund
    
    188,566 shares
    
    
    **
    
    
    
    2,045,945Thornburg International Value
    
    26,301 shares
    
    
    **
    
    
    
    734,334Total registered mutual funds
    
    
    
    
    
    
    
    
    
    
    22,299,944Collective Trust* Merrill Lynch Retirement Preservation Trust
    
    3,309,033 units
    
    
    **
    
    
    
    3,309,033Common Stock* Meridian Bioscience, Inc.
    
    5,947 shares
    
    
    **
    
    
    
    137,729* Participant Loans
    
    Interest rates ranging from 4.25% to 10.50%, maturing through 2015
    
    
    
    
    
    
    645,375Total assets held for investment purposes
    
    
    
    
    
    
    
    
    
    $
    26,392,081
 *
    
    Indicates party-in-interest.**
    
    Cost of asset is not required to be disclosed as investment is participant-directed.  14




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Meridian Bioscience, Inc. Savings and Investment PlanDate: June 29, 2011
    By:
    /s/    Melissa A. LuekeMelissa A. LuekeExecutive Vice President Finance,
Chief Financial Officer  15




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INDEX TO EXHIBITS
 Exhibit No.
    
    Description23.1
    
    
    Consent of Grant Thornton LLP
  16