EXHIBIT 10(an)
                                                                  --------------

                               AMENDMENT No. 1 to
                           PURCHASE AND SALE AGREEMENT
                        50MW SOLAR MODULE PRODUCTION LINE

                                     Between

                                SPIRE CORPORATION
                                       and
                               UNI-CHEM CO., LTD.

     This Amendment is made effective September 17, 2009, by and between Spire
Corporation ("Spire") and Uni-CHEM Co., Ltd. ("Uni-CHEM") to amend the Purchase
and Sale Agreement: 50MW Solar Module Production Line dated August 26, 2009
("Module Agreement"; individually referred to as "Party" and collectively
referred to as "Parties").


WHEREAS, the Parties entered into a Module Agreement on August 26, 2009;

WHEREAS, the Parties intend to restate and revise certain intents and
obligations within the MOA;

NOW THEREFORE, the Parties agree to and shall amend the Module Agreement as
follows:

     1.   The first paragraph in Article 3 shall be replaced entirely with the
          following:

          "The Products bought by Buyer and sold by Seller are set forth in this
          Article below and will be shipped to Buyer on or before July 1, 2010.
          (reference section 5d) The capacity of the line is based on twenty
          four-hours per-day, seven days per-week, fifty weeks per-year
          operation. The exact dimensions and specs of the modules to be
          produced shall be mutually agreed on in writing by the Parties at a
          future date. Partial shipments are allowed as needed and any shipment
          may be transshipped as may be appropriate. The specifications of the
          Products are delineated in Attachment B hereto:"

     2.   Article 3 (NOTE) shall be amended to state that the shipment schedule
          is contingent on Seller's receipt of Buyer's initial non-refundable
          down payment on or before November 20, 2009.

     3.   Article 4(c1) shall be amended to state that the shipment schedule is
          contingent on Seller's receipt of Buyer's initial non-refundable down
          payment on or before November 20, 2009.

     4.   Article 4(c2) shall be amended to state that the Letter of Credit
          shall be established on or before April 1, 2010.
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     5.   Article 5(a)(ii) shall be amended to state that the down payment shall
          be received on or before November 20, 2009.

     6.   Article 5(d) shall be replaced entirely with the following:

          "To accommodate the Buyer's request for an earlier start date on ther
          Module line, the Seller will install a 25MW semi automated line by
          April 15, 2010. The line will be operational and producing functional
          PV modules. During the operation of the 25MW semi automated line, the
          Buyer will be phasing in the Fully Automated Line of 50MW starting in
          July 2010. During the phase-in period, the 25MW semi automated line
          will continue to be fully operational until the 50MW Fully automated
          Line is complete."

     7.   Attachment A(11) shall be amended to state that shipment will be made
          "on or before July 1, 2010."

Except as expressly set forth herein, all other terms and conditions of the
Module Agreement shall remain unchanged.

IN WITNESS WHEREOF, the parties hereto have executed this Agreement and these
Amendments as of the date first above written.


Offered By:                             Acknowledged and Accepted By:


Spire Corporation                       Uni-CHEM CO., Ltd.

/s/ Rodger W. LaFavre                   /s/ Hochan Lee
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By                                      By

C.O.O.                                  Chairman
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Title                                   Title

Sept. 17, 2009                          September 17, 2009
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Date                                    Date