exv4w3



 

  

Exhibit
4.3






	COMMON STOCK COMMON STOCK PAR VALUE $0.01 PAR VALUE $0.01




	NSPH




	NANOSPHERE, INC.




	INCORPORATED UNDER THE LAWS CUSIP 63009F 10 5 OF THE STATE OF DELAWARE




	SEE REVERSE FOR CERTAIN DEFINITIONS




	This is to Certify that
BY            COUNTERSIGNED




	AND REGISTERED:




	is the owner of




	FULLY PAID AND NON-ASSESSABLE SHARES OF COMMON STOCK, PAR VALUE $0.01 PER
SHARE, OF




	NANOSPHERE, INC. (the “Corporation”) transferable only on the books of the Corporation by the
holder hereof in person or by duly authorized attorney or legal representative, upon surrender of
this Certificate properly endorsed. This Certificate is not valid unless countersigned and
registered by the Transfer Agent and Registrar.




	WITNESS the facsimile signatures of the duly authorized officers of
the Corporation. Dated:




	AUTHORIZED TRANSFER AGENT AND AMERICAN STOCK TRANSFER & TRUST COMPANY

SIGNATURE REGISTRAR




	CHIEF FINANCIAL OFFICER AND TREASURER PRESIDENT AND CHIEF EXECUTIVE OFFICER




	AMERICAN BANK NOTE COMPANY PRODUCTION COORDINATOR: TODD DeROSSETT 931-490-1720




	711 ARMSTRONG LANE PROOF OF: OCTOBER 25, 2007




	COLUMBIA, TENNESSEE 38401 NANOSPHERE, INC. (931)
388-3003 TSB 28537 FC




	SALES: PATRICK SHEERIN 773-523-8171 OPERATOR: AP 7 / LIVE
JOBS / N / NANOSPHERE 28537 FC NEW




	COLORS SELECTED FOR PRINTING: Logo prints PMS 293 AND COOL GRAY 8. Intaglio prints in SC-7 dark
blue.




	COLOR: This proof was printed from a digital file or artwork on a graphics quality, color laser
printer. It is a good representation of the color as it will appear on the final product. However,
it is not an exact color rendition, and the final printed product may appear slightly different
from the proof due to the difference between the dyes and printing ink.




	PLEASE INITIAL THE APPROPRIATE SELECTION FOR THIS PROOF: OK AS IS OK WITH CHANGES MAKE CHANGES AND
SEND ANOTHER PROOF





 









 









	The following abbreviations, when used in the inscription on the face of this certificate,
shall be construed as though they were written out in full according to applicable laws or
regulations:




	TEN COM — as tenants in common
UNIF GIFT MIN ACT — Custodian




	TEN ENT — as tenants by the entireties (Cust) (Minor) JT TEN — as joint tenants with right of
under Uniform Gifts to Minors survivorship and not as tenants Act in common




	(State)
UNIF TRF MIN ACT — Custodian (until age )




	(Cust) under
Uniform Transfers




	(Minor) to
Minors Act




	(State)
Additional abbreviations may also be used though not in the above list.
FOR VALUE RECEIVED, hereby sell, assign and transfer unto




	PLEASE INSERT SOCIAL SECURITY OR OTHER




	IDENTIFYING NUMBER OF ASSIGNEE




	(PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE)




	Shares of the capital stock represented by the within Certificate, and do hereby irrevocably
constitute and appoint




	Attorney to transfer the said stock on the books of the within named Corporation with full
power of substitution in the premises.




	Dated




	NOTICE: THE SIGNATURE(S) TO THIS ASSIGNMENT MUST CORRESPOND WITH
THE NAME(S) AS WRITTEN UPON THE FACE OF




	THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION
OR ENLARGEMENT OR ANY CHANGE WHATEVER.




	SIGNATURE(S) GUARANTEED:




	THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN
ELIGIBLE GUARANTOR INSTITUTION (BANKS,
STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND
CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED
SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT
TO S.E.C. RULE 17Ad-15.