| **Commitments and Contingencies (Details) (USD $)In Thousands, unless otherwise specified** | 12 Months Ended                                                                                                                                                                                                                                              |
|---------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
||
| **Future minimum annual payments under operating lease agreements [Abstract]**              |                                                                                                                                                                                                                                                         |   |   |
| 2013                                                                                        | $ 2,410                                                                                                                                                                                                                                                      |   |   |
| 2014                                                                                        | 2,410                                                                                                                                                                                                                                                        |   |   |
| 2015                                                                                        | 2,470                                                                                                                                                                                                                                                        |   |   |
| 2016                                                                                        | 2,532                                                                                                                                                                                                                                                        |   |   |
| 2017                                                                                        | 2,595                                                                                                                                                                                                                                                        |   |   |
| Thereafter                                                                                  | 8,182                                                                                                                                                                                                                                                        |   |   |
| Total                                                                                       | 20,599                                                                                                                                                                                                                                                       |   |   |
| Rental expense                                                                              | 2,074                                                                                                                                                                                                                                                        | 3,475 | 3,544 |
| Adjustments to rental expense                                                               | 419                                                                                                                                                                                                                                                          | 63 | 181 |
| Additional facility charges                                                                 | 2,845                                                                                                                                                                                                                                                        | 4,033 | 3,645 |
| **Licensing, Service, Supply and Related Party Agreements [Abstract]**                      |                                                                                                                                                                                                                                                         |   |   |
| License fees and supply costs                                                               | 1,170                                                                                                                                                                                                                                                        | 578 | 1,266 |
| **Consulting Agreements [Abstract]**                                                        |                                                                                                                                                                                                                                                         |   |   |
| Expenses with regard to consulting agreements with scientific specialists                   | 8                                                                                                                                                                                                                                                            | 27 | 179 |
| Fair value of options vested included in consulting expenses (in dollars per share)         |                                                                                                                                                                                                                                                         | 11 | 42 |
| **Retirement Agreement [Abstract]**                                                         |                                                                                                                                                                                                                                                         |   |   |
| Expenses for termination of employment agreement                                            | 1,789                                                                                                                                                                                                                                                        |   |   |
| **MTS-Related Party Agreement**                                                             |                                                                                                                                                                                                                                                         |   |   |
| Consulting agreement monthly retainer amount                                                | 10                                                                                                                                                                                                                                                           |   |   |
| Success fee                                                                                 | 300                                                                                                                                                                                                                                                          |   |   |
| Lonza Sales AG [Member] | Parent Company [Member]                                           |                                                                                                                                                                                                                                                         |   |   |
| **Licensing, Service, Supply and Related Party Agreements [Abstract]**                      |                                                                                                                                                                                                                                                         |   |   |
| Commitments, paid from inception                                                            | 909                                                                                                                                                                                                                                                          |   |   |
| Future Commitments                                                                          | 808                                                                                                                                                                                                                                                          |   |   |
| Terms                                                                                       | Annual license fee payments, milestones and royalties, as applicable, in respect of oncology and other products.                                                                                                                                             |   |   |
| Seattle Genetics, Inc. [Member] | PSMA Development Company LLC [Member]                     |                                                                                                                                                                                                                                                         |   |   |
| **Licensing, Service, Supply and Related Party Agreements [Abstract]**                      |                                                                                                                                                                                                                                                         |   |   |
| Commitments, paid from inception                                                            | 4,400                                                                                                                                                                                                                                                        |   |   |
| Future Commitments                                                                          | 13,800                                                                                                                                                                                                                                                       |   |   |
| Terms                                                                                       | Milestone and periodic maintenance payments to use ADC technology to link chemotherapeutic agents to monoclonal antibodies that target prostate specific membrane antigen. ADC technology is based in part on technology licensed by SGI from third parties. |   |   |
| Amgen Fremont, Inc. (formerly Abgenix) [Member] | PSMA Development Company LLC [Member]     |                                                                                                                                                                                                                                                         |   |   |
| **Licensing, Service, Supply and Related Party Agreements [Abstract]**                      |                                                                                                                                                                                                                                                         |   |   |
| Commitments, paid from inception                                                            | 1,350                                                                                                                                                                                                                                                        |   |   |
| Future Commitments                                                                          | 5,750                                                                                                                                                                                                                                                        |   |   |
| Terms                                                                                       | Milestones and royalties to use XenoMouse® technology for generating fully human antibodies to PSMA LLC's PSMA antigen.                                                                                                                                 |   |   |
| Former Member of PSMA LLC [Member] | PSMA Development Company LLC [Member]                  |                                                                                                                                                                                                                                                         |   |   |
| **Licensing, Service, Supply and Related Party Agreements [Abstract]**                      |                                                                                                                                                                                                                                                         |   |   |
| Commitments, paid from inception                                                            | 241                                                                                                                                                                                                                                                          |   |   |
| Future Commitments                                                                          | $ 52,216                                                                                                                                                                                                                                                     |   |   |
| Terms                                                                                       | Annual minimum royalty payments and milestones to use technology related to PSMA.                                                                                                                                                                            |   |   |

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Amount of required minimum rental payments maturing in the next fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Amount of required minimum rental payments maturing in the fifth fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Amount of required minimum rental payments maturing in the forth fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Amount of required minimum rental payments maturing in the third fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Amount of required minimum rental payments maturing in the second fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Amount of required minimum rental payments maturing after the fifth fiscal year following the latest fiscal year for operating leases having an initial or remaining non-cancelable letter-terms in excess of one year.
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Rental expense for the reporting period incurred under operating leases, including minimum and any contingent rent expense, net of related sublease income.
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A fee charged for services from professionals such as doctors, lawyers and accountants. The term is often expanded to include other professions, for example, pharmacists charging to maintain a medicinal profile of a client or customer.
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Fair value of options vested. Excludes equity instruments other than options, for example, but not limited to, share units, stock appreciation rights, restricted stock.
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