| **Accounts Receivable (Details) (USD $)In Thousands, unless otherwise specified** | Dec. 31, 2013 | Dec. 31, 2012 |
|-----------------------------------------------------------------------------------|---------------|---------------|
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | $ 2,879       | $ 6,937       |
| Allowance for Doubtful Accounts Receivable                                        | (7)           | 0             |
| Collaborators [Member]                                                            |          |          |
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | 12            | 6,125         |
| Royalties [Member]                                                                |          |          |
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | 2,862         | 781           |
| Research grants [Member]                                                          |          |          |
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | 0             | 12            |
| Other [Member]                                                                    |          |          |
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | 12            | 19            |
| Subtotal [Member]                                                                 |          |          |
| **Accounts, Notes, Loans and Financing Receivable [Line Items]**                  |          |          |
| Accounts receivable                                                               | $ 2,886       | $ 6,937       |

| X                                                                                                                                                                            |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| - Details**Name:**us-gaap_AccountsNotesAndLoansReceivableLineItems**Namespace Prefix:**us-gaap_**Data Type:**xbrli:stringItemType**Balance Type:**na**Period Type:**duration |
| X                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               |
|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| - Definition
Amount due from customers or clients, within one year of the balance sheet date (or the normal operating cycle, whichever is longer), for goods or services (including trade receivables) that have been delivered or sold in the normal course of business, reduced to the estimated net realizable fair value by an allowance established by the entity of the amount it deems uncertain of collection.
+ References
Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.3-4) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 3 -Subparagraph a(1) -Article 5Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 4 -Article 5
+ Details**Name:**us-gaap_AccountsReceivableNetCurrent**Namespace Prefix:**us-gaap_**Data Type:**xbrli:monetaryItemType**Balance Type:**debit**Period Type:**instant |
| X                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| - Definition
For an unclassified balance sheet, a valuation allowance for receivables due a company that are expected to be uncollectible.
+ References
Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 4 -Article 5Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section 50 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=28368275&loc=d3e5074-111524Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.4) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682
+ Details**Name:**us-gaap_AllowanceForDoubtfulAccountsReceivable**Namespace Prefix:**us-gaap_**Data Type:**xbrli:monetaryItemType**Balance Type:**credit**Period Type:**instant |