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[Federal Register Volume 76, Number 81 (Wednesday, April 27, 2011)]
[Notices]
[Pages 23600-23601]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-10146]

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency for Toxic Substances and Disease Registry

[CDC-2011-0005]

Availability of Draft Toxicological Profile

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR), 
Department of Health and Human Services (DHHS).

ACTION: Notice of availability.

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SUMMARY: This notice announces the availability of the Toxicological 
Profile for Uranium (Update) for review and comment. These comments can 
include additional information or reports on studies about the health 
effects of uranium. Although ATSDR considered key studies for uranium 
during the profile development process, this Federal Register notice 
solicits any relevant, additional studies, particularly unpublished 
data. ATSDR will evaluate the quality and relevance of such data or 
studies for possible addition to the profile. ATSDR remains committed 
to providing a public comment period for this document as a means to 
best serve public health and our clients.
    The Comprehensive Environmental Response, Compensation, and 
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments 
and Reauthorization Act of 1986 (SARA), Sec.  104(i)(3), [42 U.S.C. 
9604(i)(3)], directs the ATSDR administrator to prepare toxicological 
profiles of priority hazardous substances and, as necessary, to revise 
and publish each updated toxicological profile.

DATES: To be considered, comments on this draft toxicological profile 
must be received not later than July 29th, 2011. Comments received 
after the close of the public comment period will be considered at the 
discretion of ATSDR, based upon what is deemed to be in the best 
interest of the general public.

ADDRESSES: Requests for printed copies of the draft toxicological 
profile should be sent via e-mail to cdcinfo@cdc.gov, or

[[Page 23601]]

to Ms. Delores Grant, Division of Toxicology and Environmental 
Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F-
62, 1600 Clifton Road, NE., Atlanta, Georgia 30333. Electronic access 
to this document is also available at the ATSDR Web site: http://www.atsdr.cdc.gov/toxprofiles/index.asp.
    Electronic comments may be sent via http://www.regulations.gov, 
docket control number CDC-2011-0005. Please follow the directions on 
the site to submit comments. Comments may also be sent to the attention 
of Ms. Nickolette Roney, Division of Toxicology and Environmental 
Medicine, Agency for Toxic Substances and Disease Registry, Mailstop F-
62, 1600 Clifton Road, NE., Atlanta, Georgia 30333, e-mail: 
tppubliccomment@cdc.gov. Send one copy of all comments and three copies 
of all supporting documents. Because all public comments regarding 
ATSDR toxicological profiles are available for public inspection, no 
confidential business information or other confidential information 
should be submitted in response to this notice.

FOR FURTHER INFORMATION CONTACT: Ms. Delores Grant, Division of 
Toxicology and Environmental Medicine, Agency for Toxic Substances and 
Disease Registry, Mailstop F-62, 1600 Clifton Road, NE., Atlanta, 
Georgia 30333, telephone (770) 488-3351.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization 
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental 
Response, Compensation, and Liability Act (CERCLA or Superfund) (42 
U.S.C. 9601 et seq.) by establishing certain responsibilities for ATSDR 
and the U.S. Environmental Protection Agency (U.S. EPA) with regard to 
hazardous substances most commonly found at facilities on the CERCLA 
National Priorities List (NPL). As part of these responsibilities, the 
ATSDR administrator must prepare toxicological profiles for substances 
enumerated on the priority list of hazardous substances. This list 
identifies 275 hazardous substances which, according to ATSDR and U.S. 
EPA, pose the most significant potential threat to human health. The 
availability of the revised priority list of 275 hazardous substances 
was announced in the Federal Register on March 6, 2008 (73 FR 12178). 
In addition, ATSDR has the authority to prepare toxicological profiles 
for substances not found at sites on the National Priorities List, in 
an effort to ``* * * establish and maintain inventory of literature, 
research, and studies on the health effects of toxic substances'' under 
CERCLA Section 104(i)(1)(B), to respond to requests for consultation 
under section 104(i)(4), and as otherwise necessary to support the 
site-specific response actions conducted by ATSDR.
    Each profile will include an examination, a summary, and an 
interpretation of available toxicological information and 
epidemiological evaluations. This information and these data identify 
the levels of significant human exposure for the substance and for the 
associated health effects. The profiles must also include a 
determination of whether adequate information on the health effects of 
each substance is available or is in the process of development. If 
adequate information is not available, ATSDR, in cooperation with the 
National Toxicology Program (NTP), is required to ensure the initiation 
of research to determine such health effects.
    All toxicological profiles issued as ``Drafts for Public Comment'' 
represent ATSDR's best efforts to provide important toxicological 
information on priority hazardous substances.
    The draft toxicological profile will be made available to the 
public on or about April 29th, 2011.

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                    Hazardous substance                        CAS No.
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Uranium (Update)...........................................    7440-61-1
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    Dated: April 21, 2011.
Ken Rose,
Director, Office of Policy, Planning and Evaluation, National Center 
for Environmental Health/Agency for Toxic Substances and Disease 
Registry.
[FR Doc. 2011-10146 Filed 4-26-11; 8:45 am]
BILLING CODE 4163-70-P
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