----

----

----

----

----

| Amount    | Event  |
|-----------|--------|
|      |   |
| (1) [*].- | [*]    |
|      |   |
| (2) [*].- | [*]    |
|      |   |
| (3) [*].- | [*]    |
|      |   |
| (4) [*].- | [*]    |

----

|  | (1) | File an IND or an exploratory IND or a European equivalent within [*] of the Effective Date; and |
|--|-----|------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

|  | (2) | File a NDA or an European equivalent within [*] (or as otherwise mutually agreed by the Parties) of filing an IND or an exploratory IND or a European equivalent; and |
|--|-----|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

| (a) | Progress Reports. |
|-----|------------------------|

----

----

----

----

----

----

----

----

----

----

----

| LICENSOR--University of Zurich                                                                                     |                  |
|-------------------------------------------------------------------------------------------------------------------------|-----------------------|
| Date: April 11, 2012                                                                                               |                  |
| By:  Prof. Dr. Roger Alberto                                                                   | /s/ Roger Alberto     |
|                                                                                                                    | (Signature)           |
| Date: April 11, 2012                                                                                               |                  |
| By:  Prof. Dr. Daniel Wyler      Vice President                  | /s/ Daniel Wyler      |
|                                                                                                                    | (Signature)           |
| LICENSOR--Paul Scherrer lnstitut                                                                                        |                  |
|  Date: May 2, 2012                                                                                            |                  |
| By:            Prof. Dr. Joel Mesot Director | /s/ Joel Mesot        |
|  Date: May 4, 2012                                                                                            | (Signature)      |
| By:  Prof. Dr. Gebhard F. X. Schertler                                          | /s/ Gebhard Schertler |
|                                                                                                                    | (Signature)           |
|                                                                                                                    |                       |
| LICENSEE- MOLECULAR INSIGHT PHARMACEUTICALS, INC.                                              |                  |
| Date: May 2, 2012                                                                                                  | /s/ John Babich       |
| By:  John Babich, President                                                                    | (Signature)      |

----

----