| Name                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |   | Jurisdiction of Incorporation |
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|-------------------------------|
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |   |                          |
| Excelsior Life Sciences Ireland Limited                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          |   | Ireland                       |
| Molecular Insight Pharmaceuticals, Inc.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          |        | Delaware                      |
| Molecular Insight Limited*                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       |        | England and Wales             |
| Progenics Life Sciences Limited                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |   | England and Wales             |
| Progenics Pharmaceuticals Nevada, Inc.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |   | Nevada                        |
| PSMA Development Company LLC                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     |   | Delaware                      |
|                                                                                                          |   |                          |
| * Subsidiary of Molecular Insight Pharmaceuticals, Inc.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          |   |                          |