| **Income Taxes (Tables)**                       | 12 Months Ended                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |
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| **Income Taxes [Abstract]**                     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    |
| Schedule of deferred tax assets and liabilities | Deferred tax assets and liabilities as of December 31, 2012 and 2011, consisted of the following:  2012  2011 Deferred tax assets:    Depreciation and amortization $6,497  $6,865 R&E tax credit carry-forwards  11,843   11,966 NYS investment tax credit carry-forwards  1,084   1,088 AMT credit carry-forwards  211   211 Net operating loss carry-forwards  112,966   85,110 Capitalized research and development expenditures  30,884   43,113 Stock compensation  14,436   13,789 Other items  2,193   3,600 Total gross deferred tax assets  180,114   165,742 Less: Valuation allowance  (178,045)  (165,742)Deferred tax assets  2,069   - Deferred tax liability - current  (2,069)  - Net deferred tax asset (liability) $-  $-   |
| Schedule of reconciliation of income taxes      | The following is a reconciliation of income taxes computed at the Federal statutory income tax rate to the actual effective income tax provision during 2012, 2011 and 2010:  2012 2011 2010       U.S. Federal statutory rate   (35.0)%   35.0%   (34.0)%State income taxes, net of Federal benefit (5.4) 8.0 (5.1)Research and experimental tax credit - (4.1) (1.7)Change in valuation allowance 34.7 (22.6) 38.2Effect of federal tax rate bracket change on valuation allowance - (34.8) -Equity compensation 4.2 17.0 2.3Investment tax credit - (0.1) 0.1Other 1.5 1.6 0.1Income tax provision (benefit)    0.0%    0.0%    (0.1)%                                                                                                                                                                                                                                                      |

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| - Definition
Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.
+ References
Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319
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| - Definition
Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.
+ References
Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319
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