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CHAPTER TWO 

TABLE OF CONTENTS 

Section Page 

2.0 INTRODUCTION 1 

2.1 GUIDANCE REGARDING FLEXIBILITY INHERENT TO SW-846 METHODS AND THE 2 

PRECEDENCE OF SW-846 QUALITY CONTROL CRITERIA 

2.2 INFORMATION NECESSARY FOR CHOOSING THE CORRECT PROCEDURE 4 

2.3 CHOOSING PROCEDURES FOR ORGANIC ANALYSES 7 

2.4 CHOOSING PROCEDURES FOR CHARACTERISTIC ANALYSES 11 

2.5 CHOOSING PROCEDURES FOR GROUNDWATER ANALYSES 11

2.6 CHOOSING PROCEDURES FOR INORGANIC ANALYSES 12 

2.7 REFERENCES 12 

TABLE 

2-1 DETERMINATIVE METHODS FOR ORGANIC ANALYTES 13 

2-2 METHOD 8011 (MICROEXTRACTION AND GAS CHROMATOGRAPHY) 30 

2-3 METHOD 8015 (GC/FID) - NONHALOGENATED VOLATILES 30 

2-4 METHOD 8021 (GC, PHOTOIONIZATION AND ELECTROLYTIC CONDUCTIVITY 31 

DETECTORS) - AROMATIC AND HALOGENATED VOLATILES 

2-5 METHODS 8031 AND 8033 (GC WITH NITROGEN-PHOSPHORUS DETECTION) 32 

AND METHOD 8032 (GC WITH ELECTRON CAPTURE DETECTION) 

2-6 METHOD 8041 (GC) - PHENOLS 32 

2-7 METHOD 8061 (GC/ECD) - PHTHALATE ESTERS 33 

2-8 METHOD 8070 (GC) - NITROSAMINES 33 

2-9 METHOD 8081 (GC) - ORGANOCHLORINE PESTICIDES- 34 

2-10 METHOD 8082 (GC) - POLYCHLORINATED BIPHENYLS 35 

2-11 METHOD 8085 (GC/AED) – PESTICIDES 36 

2-12 METHOD 8091 (GC) - NITROAROMATICS AND CYCLIC KETONES 38 

2-13 METHOD 8095 (GC) - EXPLOSIVES 38 

2-14 METHOD 8100 - POLYNUCLEAR AROMATIC HYDROCARBONS 39 

2-15 METHOD 8111 (GC) - HALOETHERS 39 

2-16 METHOD 8121 (GC) - CHLORINATED HYDROCARBONS 40

2-17 METHOD 8131 (GC) - ANILINE AND SELECTED DERIVATIVES 40 

2-18 METHOD 8141 (GC) - ORGANOPHOSPHORUS COMPOUNDS 41 

2-19 METHOD 8151 (GC USING METHYLATION OR PENTAFLUOROBENZYLATION 42 

DERIVATIZATION) - CHLORINATED HERBICIDES 

2-20 METHOD 8260 (GC/MS) - VOLATILE ORGANIC COMPOUNDS 42 

2-21 METHOD 8261 (VD/GC/MS) - VOLATILE ORGANIC COMPOUNDS 44 
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Table 

2-22 

CHAPTER TWO 

TABLE OF CONTENTS (continued) 

METHOD 8270 (GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDSPage 

45 

2-23 METHOD 8275 (TE/GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 50 

2-24 METHODS 8280 (HRGC/LRMS) AND 8290 (HRGC/HRMS) - POLYCHLORINATED 51 

DIBENZO-p-DIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS 

 (PCDFs) 

2-25 METHOD 8310 (HPLC) - POLYNUCLEAR AROMATIC HYDROCARBONS 51 

2-26 METHOD 8315 - CARBONYL COMPOUNDS 52 

2-27 METHOD 8316 (HPLC) 52 

2-28 METHOD 8318 (HPLC) - N-METHYLCARBAMATES 52 

2-29 METHOD 8321 (HPLC/TS/MS) - NONVOLATILE ORGANIC COMPOUNDS 53 

2-30 METHOD 8325 (HPLC/PB/MS) - NONVOLATILE ORGANIC COMPOUNDS 55 

2-31 METHOD 8330 (HPLC) - NITROAROMATICS AND NITRAMINES 55 

2-32 METHOD 8331 (HPLC) 55 

2-33 METHOD 8332 (HPLC) 56 

2-34 METHOD 8410 - SEMIVOLATILE ORGANIC COMPOUNDS 56 

2-35 METHOD 8430 (GC/FT-IR) - BIS(2-CHLOROETHYL) ETHER AND ITS HYDROLYSIS 57 

 PRODUCTS 

2-36 METHOD 8510 (COLORIMETRIC SCREENING) - RDX AND HMX 57 

2-37 METHOD 8535 (COLORIMETRIC SCREENING) - VOLATILE ORGANIC HALIDES 57 

2-38 METHOD 8540 (UV-INDUCED COLORIMETRY) - PENTACHLOROPHENOL 58 

2-39 DETERMINATIVE METHODS FOR INORGANIC ANALYTES 58 

2-40 (A) RECOMMENDED CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING 60 

 TIMES FOR ORGANIC ANALYTES 

2-40 (B) RECOMMENDED CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING 64 

 TIMES FOR INORGANIC AND OTHER ANALYTES IN AQUEOUS MATRICES 

2-41 PREPARATION METHODS FOR ORGANIC ANALYTES 66 

2-42 CLEANUP METHODS FOR ORGANIC ANALYTE EXTRACTS 70 

2-43 DETERMINATIVE METHODS ORGANIC ANALYTES 71 

2-44 PREPARATION METHODS FOR INORGANIC ANALYSES 72 

2-45 USE OF LEACHING, EXTRACTION AND DIGESTION METHODS FOR INORGANIC 73 

 ANALYSIS (IN ORDER OF INCREASING STRENGTH) 

2-46 IMMUNOASSAY SCREENING METHODS FOR ORGANIC ANALYTES 75 

FIGURE 

2-1 ORGANIC ANALYSIS OPTIONS FOR SOLID AND LIQUID MATRICES 76 

2-2 SCHEMATIC OF SEQUENCE TO DETERMINE IF A WASTE IS HAZARDOUS BY 77 

 CHARACTERISTIC 

2-3 A RECOMMENDED SW-846 METHODS FOR ANALYSIS OF EP LEACHATES 79 

2-3 B RECOMMENDED SW-846 METHODS FOR ANALYSIS OF TCLP LEACHATES 80 

2-4 A GROUNDWATER ANALYSIS - ORGANIC ANALYTES 81 

2-4 B GROUNDWATER ANALYSIS - INDICATOR ANALYTES 82 

2-4 C GROUNDWATER ANALYSIS - INORGANIC ANALYTES 83 

Appendix A SUMMARY OF UPDATES/CHANGES IN CHAPTER 2 84 
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CHAPTER TWO 

CHOOSING THE CORRECT PROCEDURE

 SW-846 is not intended to be an analytical training manual. Therefore, method 

procedures are written based on the assumption that they will be performed by analysts who are 

formally trained in at least the basic principles of chemical analysis and in the use of the subject 

technology. 

 In addition, SW-846 methods, with the exception of required method use for the analysis 

of method-defined parameters, are intended to be guidance methods which contain general 

information on how to perform an analytical procedure or technique which a laboratory can use 

as a basic starting point for generating its own detailed Standard Operating Procedure (SOP), 

either for its own general use or for a specific project application. The performance data 

included in these methods are for guidance purposes only, and are not intended to be and must 

not be used as absolute QC acceptance criteria for the purposes of laboratory accreditation. 

 

2.0 INTRODUCTION 

 The purpose of this chapter is to aid the analyst in choosing the appropriate methods for 

sample analyses, based upon the sample matrix and the analytes to be determined. The 

ultimate responsibility for producing reliable analytical results lies with the entity subject to the 

regulation. Therefore, members of the regulated community are advised to refer to this chapter 

and to consult with knowledgeable laboratory personnel when choosing the most appropriate 

suite of analytical methods. In addition, analysts and data users are advised that, except where 

explicitly specified in a regulation, the use of SW-846 methods is not mandatory in response to 

Federal testing requirements. 

 SW-846 analytical methods are written as quantitative trace analytical methods to 

demonstrate that a waste does not contain analytes of concern that cause it to be managed as 

a hazardous waste. As such, these methods typically contain relatively stringent recommended 

quality control (QC) criteria appropriate to trace analyses. However, if a particular application 

does not require data of this quality, less stringent QC criteria may and should be used. 

 The choice of the appropriate sequence of analytical methods depends on the information 

sought and on the experience of the analyst. Appropriate selection is confirmed by the usability 

of data (i.e., adequate for its intended use). The use of the recommended procedures, whether 

they are approved or mandatory, does not release the analyst from demonstrating the correct 

execution of the method. 

 Sec. 2.1 provides guidance regarding the analytical flexibility inherent to SW-846 methods 

and the precedence of various QC criteria. Sec. 2.2 reviews the information required to choose 

the correct combination of methods for an analytical procedure. Sec. 2.3 provides useful 

information on implementing the method selection guidance for organic analyses. Sec. 2.4 

provides guidance on choosing procedures for characteristic analyses. Sec. 2.5 provides 

guidance on the determination of analytes in groundwater. Finally, Sec. 2.6 provides 

information regarding choosing procedures for inorganic analyte analyses. Tables and figures 

referenced in this chapter are sequentially located after the last page chapter text. 
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2.1 GUIDANCE REGARDING FLEXIBILITY INHERENT TO SW-846 METHODS AND THE 

PRECEDENCE OF SW-846 QUALITY CONTROL CRITERIA 

 The specific products and instrument settings cited in SW-846 methods represent those 

products and settings used during method development or subsequently evaluated by the 

Agency for use in the method. Glassware, reagents, supplies, equipment and settings other 

than those listed in this manual may be employed, provided that method performance 

appropriate for the intended RCRA application has been documented. Such performance 

includes consideration of precision, accuracy (or bias), recovery, representativeness, 

comparability, and sensitivity (quantitation or reporting limits) relative to the data quality 

objectives for the intended use of the analytical results. In response to this inherent flexibility, if 

an alternative analytical procedure is employed, then EPA expects the laboratory to 

demonstrate and document that the procedure is capable of providing appropriate performance 

for its intended application. This demonstration must not be performed after the fact, but as part 

of the laboratory’s initial demonstration of proficiency with the method. The documentation 

should be in writing, maintained in the laboratory, and available for inspection upon request by 

authorized representatives of the appropriate regulatory authorities. The documentation should 

include the performance data as well as a detailed description of the procedural steps as 

performed (i.e., a written standard operating procedure). 

 Given this allowance for flexibility, EPA wishes to emphasize that this manual also 

contains procedures for "method-defined parameters," where the analytical result is wholly 

dependent on the process used to make the measurement. Examples include: the use of the 

toxicity characteristic leaching procedure (TCLP) to prepare a leachate, and the flash point, pH, 

paint filter liquids, and corrosivity tests. In these instances, changes to the specific methods 

may change the end result and incorrectly identify a waste as nonhazardous. Therefore, when 

the measurement of such method-defined parameters is required by regulation, those methods 

are not subject to the flexibility afforded in other methods. 

 Analysts and data users are advised that even for those analytes that are not methoddefined, different procedures may produce some difference in results. Common examples 

include the differences in recoveries of phenolic compounds extracted from water by separatory 

funnel (Method 3510) and continuous liquid-liquid (Method 3520) extraction techniques, 

differences in recoveries of many compounds between Soxhlet (Method 3540) and ultrasonic 

(Method 3550) extraction techniques, and differences resulting from the choice of acid digestion 

of metals (Method 3050) or microwave digestion (Method 3051). Where practical, the Agency 

has included guidance in the individual methods regarding known potential problems, and 

analysts are advised to review this information carefully in choosing or modifying analytical 

procedures. Chapter One describes a variety of QC procedures that may be used to evaluate 

the quality of the analytical results. Additional QC procedures may be described in the 

individual methods. The results of these QC procedures should be used by the analyst to 

evaluate if the analytical procedures and/or any modifications are appropriate to generate data 

of the quality necessary to satisfy the data quality needs of the intended application. 

 The performance data included in the SW-846 methods are not intended to be used as 

absolute QC acceptance criteria for method performance. The data are intended to be 

guidance, by providing typical method performance in typical matrices, to assist the analyst in 

selection of the appropriate method for the intended application. In addition, it is the 

responsibility of the laboratory to establish actual operating parameters and in-house QC 

acceptance criteria, based on its own laboratory SOPs and in-house QC program, to 
SW-846 Update V TWO - 3 Revision 5 

October 2012

demonstrate appropriate performance of the methods used in that laboratory for the RCRA 

analytical applications for which they are intended. 

 

 The regulated community is further advised that the methods here or from other sources 

need only be used for those specific analytes of concern that are subject to regulation or other 

monitoring requirements. The fact that a method provides a long list of analytes does not mean 

that each of those analytes is subject to any or all regulations, or that all of those analytes must 

be analyzed each time the method is employed, or that all of the analytes can be analyzed 

using a single sample preparation procedure. It is EPA’s intention that the target analyte list for 

any procedure includes those analytes necessary to meet the data quality objectives of the 

project, i.e., those analytes subject to monitoring requirements and set out in a RCRA permit (or 

other applicable regulation), plus those analytes used in the methods for QC purposes, such as 

surrogates, internal standards, system performance check compounds, etc. Additional 

analytes, not included on the analyte list of a particular method(s) but needed for a specific 

project, may be analyzed by that particular method(s), if appropriate performance can be 

demonstrated for the analytes of concern in the matrices of concern at the levels of concern. 

 2.1.1 Trace analysis vs. macroanalysis 

 Through the choice of sample size and concentration procedures, the methods presented 

in SW-846 were designed to address the problem of "trace" analyses (<1000 ppm), and have 

been developed for an optimized working range. These methods are also applicable to "minor" 

(1000 ppm - 10,000 ppm) and "major" (>10,000 ppm) analyses, as well, through use of 

appropriate sample preparation techniques that result in analyte concentrations within that 

optimized range. Such sample preparation techniques include: 

 1. adjustment of size of sample prepared for analysis (for homogeneous samples), 

2. adjustment of injection volumes, 

3. dilution or concentration of sample, 

4. elimination of concentration steps prescribed for "trace" analyses, and 

5. direct injection (of samples to be analyzed for volatile constituents). 

 The performance data presented in each of these methods were generated from "trace" 

analyses, and may not be applicable to "minor" and "major" analyses. Generally, extraction 

efficiency improves as concentration increases. 

CAUTION: Great care should be taken when performing trace analyses after the analysis of 

concentrated samples, given the possibility of contamination. 

 2.1.2 Choice of apparatus and preparation of reagents 

 Since many types and sizes of glassware and supplies are commercially available, and 

since it is possible to prepare reagents and standards in many different ways, the apparatus, 

reagents, and volumes included in these methods may be replaced by any similar types as long 

as this substitution does not affect the overall quality of the analyses. 

 2.1.3 Quality control criteria precedence 
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 Chapter One contains general quality control (QC) guidance for analyses using SW-846 

methods. QC guidance specific to a given analytical technique (e.g., extraction, cleanup, 

sample introduction, or analysis) may be found in Methods 3500, 3600, 5000, 7000, and 8000. 

Method-specific QC criteria may be found in Sec. 8.0 of most older individual methods, in Sec. 

9.0 of newer methods, or in Sec. 11.0 of some air sampling methods. When inconsistencies 

exist between the information in these locations, method-specific QC criteria take precedence 

over both technique-specific criteria and those criteria given in Chapter One, and techniquespecific QC criteria take precedence over the criteria in Chapter One. 

2.2 INFORMATION NECESSARY FOR CHOOSING THE CORRECT PROCEDURE 

 In order to choose the correct combination of methods to comprise the appropriate 

analytical procedure, some basic information is necessary. This includes information on: 

-The physical state of the sample 

-The analytes of interest 

-The sensitivity or quantitation limits needed 

-The analytical objective 

-Whether the purpose is quantitation or monitoring 

-What sample containers and preservation will be used and what holding times may apply 

 2.2.1 Physical state(s) of sample 

 The phase characteristics of the sample must be known. There are several general 

categories of phases into which the sample may be categorized, including: 

 Aqueous Oil or other Organic Liquid 

 Sludge Stack Sampling (VOST) Condensate

 TCLP or EP Extract Multiphase Sample 

 Solid 

 Groundwater 

 There may be a substantial degree of overlap between the phases listed above and it may 

be useful to further divide these phases in certain instances. A multiphase sample may be a 

combination of aqueous, organic liquid, sludge, and/or solid phases, and generally must 

undergo a phase separation as the first step in the analytical procedure. 

 2.2.2 Analytes of interest 

 Analytes may be divided into various classes, based on the determinative methods which 

are used to identify and quantify them. The most basic differentiation is between organic (e.g., 

carbon-containing) analytes and inorganic (e.g., metals and anions) analytes. 

 Table 2-1 is an alphabetical list of analytes cited within the SW-846 organic determinative 

methods (excludes immunoassay and other screening methods). These analytes have been 

evaluated by those methods. The methods may also be applicable to other analytes that are 

similar to those listed. Tables 2-2 through 2-38 list the analytes for each organic determinative 

method. Table 2-39 indicates which methods are applicable to inorganic analytes. 

NOTE: Analysts should review the discussion in Sec. 2.1 of this chapter with regard to the 

presence of an analyte in a method versus the need for its analysis for a given project. 
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 2.2.3 Sensitivity or quantitation limits 

 Some regulations may require a specific sensitivity or quantitation limit for an analysis, as 

in the determination of analytes for the Toxicity Characteristic (TC). Drinking water quantitation 

limits, for those specific organic and metallic analytes covered by the National Primary Drinking 

Water Regulations, are desired in the analysis of groundwater. 

 

2.2.4 Analytical objective 

 Knowledge of the analytical objective is essential in the choice of sample preparation 

procedures and in the selection of a determinative method. This is especially true when the 

sample has more than one phase. Knowledge of the analytical objective may not be possible or 

desirable at all management levels, but that information should be included in the project 

planning document and transmitted to the analytical laboratory management to ensure that the 

correct techniques are used during the analytical effort. Screening methods or composite 

sampling may be highly beneficial for some applications in order to generate a broader view of 

contaminant distribution than may be possible with a more precise and more costly method. 

Table 2-46 identifies some screening methods appropriate for different classes of organic 

chemicals in certain matrices. 

 2.2.5 Quantitation or monitoring 

 The strategy for quantitation of compounds in environmental or process samples may be 

contrasted with the strategy for collecting monitoring data. When there is little information 

available about the composition of the sample source, e.g., a well or process stream, mass 

spectral identification of organic analytes leads to fewer false positive results. Thus, the most 

practical form of quantitation for organic analytes is often mass spectral identification. However, 

where the sensitivity requirements exceed those that can be achieved using mass spectral 

methods (e.g., GC/MS or HPLC/MS), it may be necessary to employ a more sensitive 

quantitation method (e.g., electron capture). In these instances, the risk of false positive results 

may be minimized by confirming the results through a second analysis with a dissimilar detector 

or chromatographic column. Thus, the choice of technique for organic analytes may be 

governed by the quantitation limit requirements and potential interferants. 

 Similarly, the choice of technique for metals is governed by the quantitation limit 

requirements and potential interferants. 

 In contrast, monitoring samples are analyzed to confirm existing and on-going conditions, 

tracking the presence or absence of known constituents in an environmental or process matrix. 

In well-defined matrices and under stable analytical conditions, less compound-specific 

quantitation modes may be used, as the risk of false positive results is less. 

 2.2.6 Sample preservation and holding times 

 Table 2-40 provides information regarding recommended sample preservation techniques, 

sample holding times, and other information. Similar information may be found in Table 3-1 of 

Chapter Three (inorganic analytes) and Table 4-1 of Chapter Four (organic analytes). Samples 

need to be extracted and analyzed within the recommended holding times for the results to be 

considered reflective of native concentrations as collected. Analytical data generated outside of 

the recommended holding times should typically be considered as minimum values only. Such 

data may be used to demonstrate that a waste is hazardous where it shows the concentration of 
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a constituent to be above the regulatory threshold, but cannot be used to demonstrate that a 

waste is not hazardous. However, regarding the information in Table 2-40, a longer holding 

time may be appropriate if it can be demonstrated that reported concentrations are not 

adversely affected from preservation, storage and analyses performed outside the 

recommended holding times. 

2.3 CHOOSING PROCEDURES FOR ORGANIC ANALYSES 

 Table 2-1 summarizes the organic analysis options available in SW-846. 

2.3.1 Extraction and sample preparation procedures for organic analytes 

 SW-846 methods for preparing samples for organic analytes are shown in Table 2-41. 

Method 3500 and associated methods should be consulted for further details on preparing the 

sample for analysis. 

 2.3.1.1 Aqueous samples 

 Methods 3510, 3520, and 3535 may be used for extraction of the semivolatile 

organic compounds from aqueous samples. The choice of a preparative method depends 

on the sample. Method 3510, a separatory funnel liquid-liquid extraction technique, is 

appropriate for samples which will not form a persistent emulsion interface between the 

sample and the extraction solvent. The formation of an emulsion that cannot be broken up 

by mechanical techniques will prevent proper extraction of the sample. Method 3520, a 

continuous liquid-liquid extraction technique, may be used for any aqueous sample and 

will minimize emulsion formation. 

 Method 3535 is solid-phase extraction technique that has been tested for 

organochlorine pesticides, phthalate esters, polychlorinated biphenyls (PCBs), 

organophosphorus pesticides, nitroaromatics and nitramines, and some explosive 

compounds, and may be applicable to other semivolatile and extractable compounds as 

well. The aqueous sample is passed through a solid sorbent material which traps the 

analytes. They are then eluted from the solid-phase sorbent with a small volume of 

organic solvent. This technique may be used to minimize the volumes of organic solvents 

that are employed, but may not be appropriate for aqueous samples with high suspended 

solids contents. 

 2.3.1.1.1 Acidic extraction of phenols and acid analytes 

 The solvent extract obtained by performing Method 3510, 3520, or 3535 

at a pH less than or equal to 2 will contain the phenols and acid/neutral extractable 

organics of interest, and may contain some mildly basic compounds. The 

particular pH extraction conditions needs to be defined during the project planning 

process based on the desired target analytes and performance goals. 

 2.3.1.1.2 Basic or neutral extraction of semivolatile analytes 

 The solvent extract obtained by performing Method 3510, 3520, or 3535 

at a basic pH will contain the organic bases of interest, if acid extraction is 

performed first. It will also contain the neutral compounds of interest, if acid 

extraction is not performed. Refer to Table 1 in the extraction methods (3510 
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and/or 3520) for guidance on the requirements for pH adjustment prior to extraction 

and analysis. 

 2.3.1.2 Solid samples 

 Soxhlet extraction (Methods 3540, 3541 and 3542), pressurized fluid extraction 

(Method 3545), microwave extraction (Method 3546) and ultrasonic extraction (Method 

3550) may be used with solid samples. Consolidated samples should be ground finely 

enough to pass through a 1-mm sieve. In limited applications, waste dilution (Methods 

3580 and 3585) may be used if the entire sample is soluble in the specified solvent. 

 Methods 3540, 3541, 3542, 3545, 3546 and 3550 are neutral-pH extraction 

techniques and therefore, depending on the analysis requirements, acid-base partition 

cleanup (Method 3650) may be necessary. Method 3650 will only be needed if 

chromatographic interferences are severe enough to prevent quantitation of the analytes 

of interest. This separation will be most important if a GC method is chosen for analysis of 

the sample. If GC/MS is used, the ion selectivity of the technique may compensate for 

chromatographic interferences. 

 There are three extraction procedures for solid samples that employ supercritical 

fluid extraction (SFE). Method 3560 is a technique for the extraction of petroleum 

hydrocarbons from various solid matrices using carbon dioxide at elevated temperature 

and pressure. Method 3561 may be used to selectively extract polynuclear aromatic 

hydrocarbons (PAHs) from solid matrices using supercritical carbon dioxide and 

appropriate modifiers, based on the determinative procedure to be used. Method 3562 

may be used to selectively extract organochlorine pesticides or PCBs from solid matrices 

using supercritical carbon dioxide. 

 2.3.1.3 Oils and organic liquids 

 Method 3580, waste dilution, may be used to prepare oils and organic liquid 

samples for analysis of semivolatile and extractable organic analytes by GC or GC/MS. 

Method 3585 may be employed for the preparation of these matrices for volatiles analysis 

by GC or GC/MS. To avoid overloading the analytical detection system, care must be 

exercised to ensure that proper dilutions are made. Methods 3580 and 3585 give 

guidance on performing waste dilutions. 

 To remove interferences for semivolatiles and extractables, Method 3611 (Alumina 

cleanup) may be performed on an oil sample directly, without prior sample preparation. 

 Method 3650 is the only other preparative procedure for oils and other organic 

liquids. This procedure is a back extraction into an aqueous phase. It is generally 

introduced as a cleanup procedure for extracts rather than as a preparative procedure. 

Oils generally have a high concentration of semivolatile compounds and, therefore, 

preparation by Method 3650 should be done on a relatively small aliquot of the sample. 

Generally, extraction of 1 mL of oil will be sufficient to obtain a saturated aqueous phase 

and avoid emulsions. 

 NOTE: The use of traditional extraction techniques, i.e., 3510, 3520, 3535, 3540, 3541, 

3545, 3546, and 3550, is neither suitable nor recommended for use in these 
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matrices due to a high potential for hydrocarbon interferences and decreased 

determinative method sensitivity, i.e., poor analytical performance. 

 2.3.1.4 Sludge samples 

 Determining the appropriate methods for analysis of sludges is complicated 

because of the lack of precise definitions of sludges with respect to the relative percent of 

liquid and solid components. There is no set ratio of liquid to solid which enables the 

analyst to determine which of the three extraction methods cited is the most appropriate. 

Sludges may be classified into three categories: liquid sludges, solid sludges, and 

emulsions, but with appreciable overlap. 

 If the sample is an organic sludge (solid material and organic liquid, as opposed to 

an aqueous sludge), the sample should be handled as a multiphase sample. 

 

2.3.1.4.1 Liquid sludges 

 Method 3510 or Method 3520 may be applicable to sludges that behave 

like, and have the consistency of, aqueous liquids. Ultrasonic extraction (Method 

3550) and Soxhlet-type (Method 3540 series) procedures will, most likely, be 

ineffective because of the overwhelming presence of the liquid aqueous phase. 

 2.3.1.4.2 Solid sludges 

 Soxhlet extraction (Methods 3540 and 3541), pressurized fluid (Method 

3545) extraction, microwave extraction (Method 3546) and ultrasonic extraction 

(Method 3550) will be more effective when applied to sludge samples that 

resemble solids. Samples may be dried or centrifuged to form solid materials for 

subsequent determination of semivolatile compounds.

 Using Method 3650, Acid-Base Partition Cleanup, on the extract may be 

necessary, depending on whether chromatographic interferences prevent 

determination of the analytes of interest. 

 2.3.1.4.3 Emulsions 

 Attempts should be made to break up and separate the phases of an 

emulsion. Several techniques are effective in breaking emulsions or separating the 

phases of emulsions, including: 

 1. Freezing/thawing -- Certain emulsions will separate if exposed to 

temperatures below 0 °C. 

 2. Salting out -- Addition of a salt to make the aqueous phase of an emulsion too 

polar to support a less polar phase promotes separation. 

 3. Centrifugation -- Centrifugal force may separate emulsion components by 

density. 

 4. Addition of water or ethanol -- Emulsion polymers may be destabilized when a 

preponderance of the aqueous phase is added. 
SW-846 Update V TWO - 9 Revision 5 

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5. Forced filtering through glass wool -- Many emulsions can be broken by 

forcing the emulsion through a pad of Pyrex glass wool in a drying column 

using a slight amount of air pressure (using a rubber bulb usually provides 

sufficient pressure). 

 If techniques for breaking emulsions fail, use Method 3520. If the 

emulsion can be broken, the different phases (aqueous, solid, or organic liquid) 

may then be analyzed separately. 

 2.3.1.5 Multiphase samples 

 Choice of the procedure for separating multiphase samples is highly dependent on 

the objective of the analysis. With a sample in which some of the phases tend to separate 

rapidly, the percent weight or volume of each phase should be calculated and each phase 

should be individually analyzed for the required analytes. 

 

 An alternate approach is to obtain a homogeneous sample and attempt a single 

analysis on the combination of phases. This approach will give no information on the 

abundance of the analytes in the individual phases other than what can be implied by 

solubility. 

 A third alternative is to select phases of interest and to analyze only those selected 

phases. This tactic must be consistent with the sampling/analysis objectives or it will yield 

insufficient information for the time and resources expended. The phases selected should 

be compared with Figure 2-1 and Table 2-41 for further guidance. 

 2.3.2 Cleanup procedures 

 Cleanup procedure selection is determined by the analytes of interest within the extract. 

Each analyte type in Table 2-42, Cleanup Methods for Organic Analyte Extracts, corresponds to 

one or more of the possible determinative methods available in the manual. However, the 

necessity of performing cleanup may also depend upon the matrix from which the extract was 

developed. Cleanup of a sample may be done exactly as instructed in the cleanup method for 

some of the analytes. There are some instances when cleanup using one of the methods may 

only proceed after the procedure is modified to optimize recovery and separation. Several 

cleanup techniques may be possible for each analyte category. The information provided is not 

meant to imply that any or all of these methods must be used for the analysis to be acceptable. 

Extracts with components which interfere with spectral or chromatographic determinations are 

expected to be subjected to cleanup procedures. 

 The analyst in consultation with the regulator, customer and other project planning 

participants, as necessary, must determine the necessity for cleanup procedures, as there are 

no clear cut criteria for indicating their use. Method 3600 and associated methods should be 

consulted for further details on extract cleanup. 
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 2.3.3 Determinative procedures 

 In Table 2-43, the determinative methods for organic analytes are divided into four 

categories, specifically: gas chromatography/mass spectrometry (GC/MS); gas 

chromatography (GC) with electromagnetic spectrometric (ES) detectors, i.e., Fourier Transform 

infrared (FT-IR) or atomic emission (AES); specific quantitation methods, i.e., gas 

chromatography (GC) with specific non-MS detectors; and high performance liquid 

chromatography (HPLC). This division is intended to help an analyst choose which 

determinative method will apply. Under each analyte column, SW-846 method numbers are 

indicated, if appropriate, for the determination of the analyte. A blank has been left if no 

chromatographic determinative method is available. 

 Generally, the MS procedures are more specific but less sensitive than the appropriate 

gas chromatographic/specific quantitation or ES method. 

 Method 8000 gives a general description of the techniques of gas chromatography and 

high performance liquid chromatography. Method 8000 should be consulted prior to application 

of any of the gas chromatographic methods. 

 Method 8081 (organochlorine pesticides), Method 8082 (polychlorinated biphenyls), 

Method 8141 (organophosphorus pesticides), and Method 8151 (chlorinated herbicides), are 

preferred over GC/MS because of the combination of selectivity and sensitivity of the flame 

photometric, nitrogen-phosphorus, and electron capture detectors. 

 Method 8260 is a GC/MS method for volatile analytes, which employs a capillary column. 

A variety of sample introduction techniques may be used with Method 8260, including Methods 

5021, 5030, 5031, 5035, 5041, and 3585. A GC with a selective detector is also useful for the 

determination of volatile organic compounds in a monitoring scenario, as described in Sec. 

2.2.5. 

 Method 8270 is a GC/MS method for semivolatile analytes, which employs a capillary 

column. Method 8410 is another capillary GC method for semivolatile analytes which uses a 

Fourier Transform IR (FT-IR) detector. Method 8085 is a capillary GC method for pesticides 

which uses an atomic emission detector (AES). 

 Table 2-43 lists several GC and HPLC methods that apply to only a small number of 

analytes. Methods 8031 and 8033 are GC methods for acrolein, acrylonitrile, and acetonitrile. 

Methods 8315 and 8316 are HPLC methods for these three analytes. Method 8316 also 

addresses acrylamide, which may be analyzed by Method 8032. 

 HPLC methods have been developed for other types of analytes, most notably N-methyl 

carbamates (Method 8318); azo dyes, phenoxy acid herbicides, carbamates, and 

organophosphorus pesticides (Method 8321); PAHs (Method 8310); explosives (Methods 8330, 

8331, and 8332); and some volatile organics (Methods 8315 and 8316). 

 Method 8430 utilizes a fourier transform infrared spectrometer (FT-IR) coupled to a gas 

chromatograph to determine bis(2-chloroethyl) ether and its hydrolysis products. The sample is 

introduced by direct aqueous injection. Method 8440 may be employed for the determination of 

total recoverable petroleum hydrocarbons (TRPH) in solid samples by infrared (IR) 
SW-846 Update V TWO - 11 Revision 5 

October 2012

spectrophotometry. The samples may be extracted with supercritical carbon dioxide, using 

Method 3560. 

2.4 CHOOSING PROCEDURES FOR CHARACTERISTIC ANALYSES

 2.4.1 Figure 2-2 outlines a sequence for determining if a waste exhibits one or more of 

the characteristics of a hazardous waste. 

 2.4.2 EP and TCLP extracts 

 The leachate obtained from using either the EP (Figure 2-3A) or the TCLP (Figure 2-3B) is 

an aqueous sample, and therefore, requires further solvent extraction prior to the analysis of 

semivolatile compounds. 

 The TCLP leachate is solvent extracted with methylene chloride at a pH <2 and at a pH 

>11 by either Method 3510 or 3520. The leachate may also be extracted as received for 

organochlorine pesticides and semivolatiles and at pH <1.0 for phenoxyacid herbicides using 

the solid phase extraction (SPE) disk option in Method 3535. The best recoveries are usually 

obtained using either Method 3520 or Method 3535. 

 The solvent extract obtained by performing either Method 3510 or 3520 at an acidic pH will 

contain the acid/neutral compounds of interest. Refer to the specific determinative method for 

guidance on the pH requirements for extraction prior to analysis. Method 5031 (azeotropic 

distillation) may be used as an effective preparative method for pyridine. 

 Due to the high concentration of acetate in the TCLP extract, it is recommended that 

purge-and-trap be used to introduce the volatile sample into the gas chromatograph. 

 The EP and TCLP extracts can also be digested using acids (Method 3010, 3015, or 

3020) and analyzed for metals using a 6000 or 7000 series method (Figures 2-3A and 2-3B). 

2.5 CHOOSING PROCEDURES FOR GROUNDWATER ANALYSES 

 Appropriate analysis schemes for the determination of analytes in groundwater are 

presented in Figures 2-4A, 2-4B, and 2-4C. Quantitation limits for the inorganic analytes should 

correspond to the drinking water limits, where such limits are available. 

 2.5.1 Special techniques for inorganic analytes 

 All atomic absorption analyses should employ appropriate background correction systems 

whenever spectral interferences could be present. Several background correction techniques 

are employed in modern atomic absorption spectrometers. Matrix modification can complement 

background correction in some cases. Since no approach to interference correction is 

completely effective in all cases, the analyst should attempt to verify the adequacy of correction. 

If the interferant is known (e.g., high concentrations of iron in the determination of selenium), 

accurate analyses of synthetic solutions of the interferant (with and without analyte) could 

establish the efficacy of the background correction. If the nature of the interferant is not 

established, good agreement of analytical results using two substantially different wavelengths 

could substantiate the adequacy of the background correction. 
SW-846 Update V TWO - 12 Revision 5 

October 2012

 To reduce matrix interferences, all graphite furnace atomic absorption (GFAA) analyses 

should be performed using techniques which maximize an isothermal environment within the 

furnace cell. Data indicate that two such techniques, L'vov platform and the delayed 

atomization cuvette (DAC), are equivalent in this respect, and produce high quality results. 

 All furnace atomic absorption analysis should be carried out using the best matrix modifier 

for the analysis. Some examples of modifiers are listed below. (See also the appropriate 

methods.) 

Element(s) Modifier(s) 

As and Se Nickel nitrate, palladium 

Pb Phosphoric acid, ammonium phosphate, palladium 

Cd Ammonium phosphate, palladium 

Sb Ammonium nitrate, palladium 

Tl Platinum, palladium 

 ICP, AA, and GFAA calibration standards need to match the acid composition and 

strength of the acids contained in the samples. Acid strengths of the calibration standards 

should be stated in the raw data. When using a method which permits the use of internal 

standardization, and the internal standardization option is being used, matrix matching is not 

required. 

2.6 CHOOSING PROCEDURES FOR INORGANIC ANALYSES 

 Methods for preparing different sample matrices for inorganic analyses are shown in Table 

2-44. Guidance regarding the use of leaching and digestive methods for inorganic analysis is 

provided in Table 2-45. 

2.7 REFERENCES 

1. M. J. Barcelona, "TOC Determinations in Ground Water," Ground Water 1984, 22(1), 18-

24. 

2. R. Riggin, et al.; Development and Evaluation of Methods for Total Organic Halide and 

Purgeable Organic Halide in Wastewater; U.S. Environmental Protection Agency; Office of 

Research and Development; Environmental Monitoring and Support Laboratory; ORD 

Publication Offices of Center for Environmental Research Information; Cincinnati, OH, 

1984; EPA-600/4-84-008. 

3. G. McKee, et al.; Determination of Inorganic Anions in Water by Ion Chromatography

(Technical addition to Methods for Chemical Analysis of Water and Wastewater, EPA 

600/4-79-020); U.S. Environmental Protection Agency; Environmental Monitoring and 

Support Laboratory; ORD Publication Offices of Center for Environmental Research 

Information; Cincinnati, OH, 1984; EPA-600/4-84-017. 
SW-846 Update V TWO - 13 Revision 5 

October 2012

TABLE 2-1 

 DETERMINATIVE METHODS FOR ORGANIC ANALYTES 

 Analytes are listed in alphabetical order and alternative analyte names are in parenthesis. 

 The applicable method listing does not include immunoassay or screening methods. 

Analyte Applicable Method 

Abate (Temephos) ................................................................................................................ 8085 

Acenaphthene ............................................................................... 8100, 8270, 8275, 8310, 8410 

Acenaphthylene .............................................................................8100, 8270, 8275, 8310, 8410 

Acetaldehyde ........................................................................................................................ 8315 

Acetone................................................................................................... 8015, 8260, 8261, 8315 

Acetonitrile .............................................................................................. 8015, 8033, 8260, 8261 

Acetophenone ............................................................................................................. 8261, 8270 

2-Acetylaminofluorene .......................................................................................................... 8270 

1-Acetyl-2-thiourea ................................................................................................................ 8270 

Acifluorfen ................................................................................................................... 8085, 8151 

Acrolein (Propenal) ........................................................................8015, 8260, 8261, 8315, 8316 

Acrylamide .................................................................................................................. 8032, 8316 

Acrylonitrile ................................................................................... 8015, 8031, 8260, 8261, 8316 

Alachlor ........................................................................................................................ 8081,8085 

Aldicarb (Temik) .......................................................................................................... 8318, 8321 

Aldicarb sulfone .......................................................................................................... 8318, 8321 

Aldicarb sulfoxide .................................................................................................................. 8321 

Aldrin ................................................................................................................ 8081, 8085, 8270 

Allyl alcohol ................................................................................................................. 8015, 8260 

Allyl chloride ...................................................................................................... 8021, 8260, 8261 

Ametryn ................................................................................................................................ 8085 

2-Aminoanthraquinone .......................................................................................................... 8270 

Aminoazobenzene ................................................................................................................ 8270 

4-Aminobiphenyl ................................................................................................................... 8270 

Aminocarb ............................................................................................................................. 8321 

2-Amino-4,6-dinitrotoluene (2-Am-DNT) ...................................................................... 8095, 8330 

4-Amino-2,6-dinitrotoluene (4-Am-DNT) ...................................................................... 8095, 8330 

3-Amino-9-ethylcarbazole ..................................................................................................... 8270 

t-Amyl alcohol (TAA) ............................................................................................................. 8015 

t-Amyl ethyl ether (TAEE, 4,4-Dimethyl-3-oxahexane) ................................................ 8015, 8261 

t-Amyl methyl ether (TAME) ........................................................................................ 8015, 8261 

Anilazine ............................................................................................................................... 8270 

Aniline ............................................................................................................... 8131, 8261, 8270 

o-Anisidine ............................................................................................................................ 8270 

Anthracene ....................................................................................8100, 8270, 8275, 8310, 8410 

Aramite ................................................................................................................................. 8270 

Aroclor-1016 (PCB-1016) ............................................................................................ 8082, 8270 

Aroclor-1221 (PCB-1221) ............................................................................................ 8082, 8270 

Aroclor-1232 (PCB-1232) ............................................................................................ 8082, 8270 

Aroclor-1242 (PCB-1242) ............................................................................................ 8082, 8270 

Aroclor-1248 (PCB-1248) ............................................................................................ 8082, 8270 

Aroclor-1254 (PCB-1254) ............................................................................................ 8082, 8270 
SW-846 Update V TWO - 14 Revision 5 

October 2012

Aroclor-1260 (PCB-1260) ............................................................................................ 8082, 8270 

Aspon ................................................................................................................................... 8141 

Asulam .................................................................................................................................. 8321 

Atraton .................................................................................................................................. 8085 

Atrazine............................................................................................................. 8041, 8085, 8141 

Azinphos-ethyl (Ethyl guthion) ..................................................................................... 8085, 8141 

Azinphos-methyl (Guthion) ................................................................................ 8085, 8141, 8270 

Barban ........................................................................................................................ 8270, 8321 

Baygon (Propoxur) ...................................................................................................... 8318, 8321 

Bendiocarb ........................................................................................................ 8141, 8318, 8321 

Benefin ................................................................................................................................. 8091 

Benfluralin ............................................................................................................................. 8085 

Benomyl ................................................................................................................................ 8321 

Bentazon ............................................................................................................................... 8151 

Benzal chloride ..................................................................................................................... 8121 

Benzaldehyde ....................................................................................................................... 8315 

Benz(a)anthracene ........................................................................8100, 8270, 8275, 8310, 8410 

Benzene.................................................................................................. 8015, 8021, 8260, 8261 

Benzenethiol (Thiophenol) .................................................................................................... 8270 

Benzidine .................................................................................................................... 8270, 8325 

Benzo(b)fluoranthene.............................................................................. 8100, 8270, 8275, 8310 

Benzo(j)fluoranthene ............................................................................................................. 8100 

Benzo(k)fluoranthene .............................................................................. 8100, 8270, 8275, 8310 

Benzoic acid ............................................................................................................... 8270, 8410 

Benzo(g,h,i)perylene ............................................................................... 8100, 8270, 8275, 8310 

Benzo(a)pyrene .............................................................................8100, 8270, 8275, 8310, 8410 

p-Benzoquinone .................................................................................................................... 8270 

Benzotrichloride .................................................................................................................... 8121 

Benzoylprop ethyl ................................................................................................................. 8325 

Benzyl alcohol ....................................................................................................................... 8270 

Benzyl chloride.................................................................................................. 8021, 8121, 8260 

α-BHC (α-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

β-BHC (β-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

δ-BHC (δ-Hexachlorocyclohexane) ......................................................... 8081, 8085, 8121, 8270 

γ-BHC (Lindane, γ-Hexachlorocyclohexane) ........................................... 8081, 8085, 8121, 8270 

Bis(2-chloroethoxy)methane ............................................................................. 8111, 8270, 8410 

Bis(2-chloroethyl) ether .......................................................................... 8111, 8270, 8410, 8430 

Bis(2-chloroethyl)sulfide ........................................................................................................ 8260 

Bis(2-chloro-1-methylethyl) ether ............................................................ 8021, 8111, 8270, 8410 

Bis(2-n-butoxyethyl) phthalate ............................................................................................... 8061 

Bis(2-ethoxyethyl) phthalate .................................................................................................. 8061 

Bis(2-ethylhexyl) phthalate ................................................................................ 8061, 8270, 8410 

Bis(2-methoxyethyl) phthalate ............................................................................................... 8061 

Bis(4-methyl-2-pentyl)-phthalate ........................................................................................... 8061 

Bolstar (Sulprofos) ...................................................................................................... 8085, 8141 

Bromacil ...................................................................................................................... 8085, 8321 

Brominal (Bromoxynil) ................................................................................................. 8085, 8270 

Bromoacetone............................................................................................................. 8021, 8260 

4-Bromoaniline ...................................................................................................................... 8131 

Bromobenzene............................................................................................................ 8021, 8260 
SW-846 Update V TWO - 15 Revision 5 

October 2012

Bromochloromethane ........................................................................................ 8021, 8260, 8261 

2-Bromo-6-chloro-4-nitroaniline ............................................................................................. 8131 

Bromodichloromethane ..................................................................................... 8021, 8260, 8261 

2-Bromo-4,6-dinitroaniline ..................................................................................................... 8131 

Bromoform ....................................................................................................... 8021, 8260, 8261 

Bromomethane ................................................................................................. 8021, 8260, 8261 

4-Bromophenyl phenyl ether ................................................................... 8111, 8270, 8275, 8410 

Bromoxynil (Brominal) ................................................................................................. 8085, 8270 

Butachlor ............................................................................................................................... 8085 

Butanal ................................................................................................................................. 8315 

1-Butanol (n-Butyl alcohol, n-Butanol) ................................................................................... 8260 

n-Butanol (1-Butanol, n-Butyl alcohol) ................................................................................... 8260 

2-Butanone (Methyl ethyl ketone, MEK) ............................................................ 8015, 8260, 8261 

Butifos (DEF) ........................................................................................................................ 8085 

Butralin ................................................................................................................................. 8091 

n-Butyl alcohol (1-Butanol, n-Butanol) ................................................................................... 8260 

t-Butyl alcohol ............................................................................................................. 8015, 8260 

Butylate ............................................................................................................. 8085, 8141, 8321 

n-Butylbenzene ................................................................................................. 8021, 8260, 8261 

sec-Butylbenzene ............................................................................................. 8021, 8260, 8261 

tert-Butylbenzene .............................................................................................. 8021, 8260, 8261 

Butyl benzyl phthalate ....................................................................................... 8061, 8270, 8410 

2-sec-Butyl-4,6-dinitrophenol (DNBP, Dinoseb) .............................8041, 8085, 8151, 8270, 8321 

Captafol ............................................................................................................ 8081, 8085, 8270 

Captan ........................................................................................................................ 8085, 8270 

Carbaryl (Sevin) ...................................................................................... 8270, 8318, 8321, 8325 

Carbendazim ........................................................................................................................ 8321 

Carbofuran (Furaden) ....................................................................................... 8270, 8318, 8321 

Carbofuran phenol ................................................................................................................ 8321 

Carbon disulfide .......................................................................................................... 8260, 8261 

Carbon tetrachloride ............................................................................... 8021, 8260, 8261, 8535 

Carbophenothion .................................................................................... 8081, 8085, 8141, 8270 

Carbosulfan .......................................................................................................................... 8321 

Carboxin ............................................................................................................................... 8085 

Casoron (Dichlobenil) ............................................................................................................ 8085 

Chloral hydrate...................................................................................................................... 8260 

Chloramben .......................................................................................................................... 8151 

Chlordane (NOS) ........................................................................................................ 8081, 8270 

cis-Chlordane ........................................................................................................................ 8081 

trans-Chlordane .......................................................................................................... 8085, 8081 

Chlorfenvinphos .......................................................................................................... 8141, 8270 

Chloroacetonitrile .................................................................................................................. 8260 

2-Chloroaniline ...................................................................................................................... 8131 

3-Chloroaniline ...................................................................................................................... 8131 

4-Chloroaniline .................................................................................................. 8131, 8270, 8410 

Chlorobenzene.................................................................................................. 8021, 8260, 8261 

Chlorobenzilate ........................................................................................................... 8081, 8270 

2-Chlorobiphenyl ......................................................................................................... 8082, 8275 

2-Chloro-1,3-butadiene (Chloroprene) ........................................................................ 8021, 8260 

1-Chlorobutane ..................................................................................................................... 8260 

Chlorodibromomethane (Dibromochloromethane) ............................................. 8021, 8260, 8261 
SW-846 Update V TWO - 16 Revision 5 

October 2012

2-Chloro-4,6-dinitroaniline ..................................................................................................... 8131 

1-Chloro-2,4-dinitrobenzene.................................................................................................. 8091 

1-Chloro-3,4-dinitrobenzene.................................................................................................. 8091 

Chloroethane .................................................................................................... 8021, 8260, 8261 

2-Chloroethanol ................................................................................................ 8021, 8260, 8430 

2-(2-Chloroethoxy)ethanol .................................................................................................... 8430 

2-Chloroethyl vinyl ether ............................................................................................. 8021, 8260 

Chloroform ........................................................................................................ 8021, 8260, 8261 

1-Chlorohexane .................................................................................................................... 8260 

Chloromethane ................................................................................................. 8021, 8260, 8261 

5-Chloro-2-methylaniline ....................................................................................................... 8270 

Chloromethyl methyl ether .................................................................................................... 8021 

2-Chloro-5-methylphenol ....................................................................................................... 8041 

4-Chloro-2-methylphenol ....................................................................................................... 8041 

4-Chloro-3-methylphenol ................................................................................... 8041, 8270, 8410 

3-(Chloromethyl)pyridine hydrochloride ................................................................................. 8270 

1-Chloronaphthalene.................................................................................................. 8270, 8275 

2-Chloronaphthalene......................................................................................... 8121, 8270, 8410 

Chloroneb ............................................................................................................................. 8081 

2-Chloro-4-nitroaniline ........................................................................................................... 8131 

4-Chloro-2-nitroaniline ........................................................................................................... 8131 

1-Chloro-2-nitrobenzene ....................................................................................................... 8091 

1-Chloro-4-nitrobenzene ....................................................................................................... 8091 

2-Chloro-6-nitrotoluene ......................................................................................................... 8091 

4-Chloro-2-nitrotoluene ......................................................................................................... 8091 

4-Chloro-3-nitrotoluene ......................................................................................................... 8091 

2-Chlorophenol ................................................................................................. 8041, 8270, 8410 

3-Chlorophenol ..................................................................................................................... 8041 

4-Chlorophenol ..................................................................................................................... 8410 

4-Chloro-1,2-phenylenediamine ............................................................................................ 8270 

4-Chloro-1,3-phenylenediamine ............................................................................................ 8270 

4-Chlorophenyl phenyl ether ............................................................................. 8111, 8270, 8410 

2-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

3-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

4-Chlorophenyl 4-nitrophenyl ether ....................................................................................... 8111 

o-Chlorophenyl thiourea ........................................................................................................ 8325 

Chloroprene (2-Chloro-1,3-butadiene) ........................................................................ 8021, 8260 

3-Chloropropionitrile .............................................................................................................. 8260 

Chloropropham ........................................................................................................... 8085, 8321 

Chloropropylate ..................................................................................................................... 8081 

Chlorothalonil ........................................................................................................................ 8081 

2-Chlorotoluene ................................................................................................ 8021, 8260, 8261 

4-Chlorotoluene ................................................................................................ 8021, 8260, 8261 

Chloroxuron .......................................................................................................................... 8321 

Chlorpyrifos ................................................................................................................. 8085, 8141 

Chlorpyrifos methyl ............................................................................................................... 8141 

Chlorthalonil (Daconil) ........................................................................................................... 8085 

Chrysene .......................................................................................8100, 8270, 8275, 8310, 8410 

Coumaphos ..................................................................................................... 8085, 8141, 8270 

p-Cresidine ........................................................................................................................... 8270 

o-Cresol (2-Methylphenol) ................................................................................. 8041, 8270, 8410 
SW-846 Update V TWO - 17 Revision 5 

October 2012

m-Cresol (3-Methylphenol) .......................................................................................... 8041, 8270 

p-Cresol (4-Methylphenol) ................................................................................. 8041, 8270, 8410 

Crotonaldehyde ................................................................................................. 8015, 8260, 8315 

Crotoxyphos ................................................................................................................ 8141, 8270 

m-Cumenyl methylcarbamate ..................................................................................... 8318, 8321 

Cyanazine ............................................................................................................................. 8085 

Cycloate ................................................................................................................................ 8085 

Cyclohexanone ..................................................................................................................... 8315 

2-Cyclohexyl-4,6-dinitrophenol .................................................................................... 8041, 8270 

2,4-D ........................................................................................................................... 8151, 8321 

2,4-D (acid) ........................................................................................................................... 8085 

2,4-D (butoxyethanol ester) ................................................................................................... 8321 

2,4-D (ethylhexyl ester) ......................................................................................................... 8321 

Dacthal (DCPA) .......................................................................................................... 8081, 8085 

Daconil (Chlorthalonil) ........................................................................................................... 8085 

Dalapon ...................................................................................................................... 8151, 8321 

2,4-DB ........................................................................................................................ 8151, 8321 

2,4-DB (acid) ......................................................................................................................... 8085 

DBCP (1,2-Dibromo-3-chloropropane) ................................. 8011, 8021, 8081, 8260, 8261, 8270 

2,4-D, butoxyethanol ester .................................................................................................... 8321 

DCM (Dichloromethane, Methylene chloride) .................................................... 8021, 8260, 8261 

DCPA (Dacthal) .......................................................................................................... 8081, 8085 

DCPA diacid ......................................................................................................................... 8151 

2,4'-DDD ............................................................................................................................... 8085 

4,4'-DDD ........................................................................................................... 8081, 8085, 8270 

2,4'-DDE ............................................................................................................................... 8085 

4,4'-DDE ........................................................................................................... 8081, 8085, 8270 

2,4'-DDT ............................................................................................................................... 8085 

4,4'-DDT ........................................................................................................... 8081, 8085, 8270 

DDVP (Dichlorvos, Dichlorovos) ............................................................. 8085, 8141, 8270, 8321 

2,2',3,3'4,4'5,5',6,6'-Decachlorobiphenyl ............................................................................... 8275 

Decanal................................................................................................................................. 8315 

DEF (Butifos) ........................................................................................................................ 8085 

Demeton-O, and Demeton-S ............................................................................. 8085, 8141, 8270 

2,4-D, ethylhexyl ester .......................................................................................................... 8321 

Diallate .............................................................................................................. 8081, 8085, 8270 

Diamyl phthalate ................................................................................................................... 8061 

2,4-Diaminotoluene ............................................................................................................... 8270 

Diazinon ...................................................................................................................... 8085, 8141 

Dibenz(a,h)acridine ............................................................................................................... 8100 

Dibenz(a,j)acridine ...................................................................................................... 8100, 8270 

Dibenz(a,h)anthracene ............................................................................ 8100, 8270, 8275, 8310 

7H-Dibenzo(c,g)carbazole .................................................................................................... 8100 

Dibenzofuran .................................................................................................... 8270, 8275, 8410 

Dibenzo(a,e)pyrene .................................................................................................... 8100, 8270 

Dibenzo(a,h)pyrene .............................................................................................................. 8100 

Dibenzo(a,i)pyrene ................................................................................................................ 8100 

Dibenzothiophene ................................................................................................................. 8275 

Dibromochloromethane (Chlorodibromomethane) ............................................. 8021, 8260, 8261 

1,2-Dibromo-3-chloropropane (DBCP) ................................. 8011, 8021, 8081, 8260, 8261, 8270 

Dibromofluoromethane .......................................................................................................... 8260 
SW-846 Update V TWO - 18 Revision 5 

October 2012

Dibromomethane .............................................................................................. 8021, 8260, 8261 

1,2-Dibromoethane (EDB, Ethylene dibromide) ................................................. 8011, 8021, 8260 

2,6-Dibromo-4-nitroaniline ..................................................................................................... 8131 

2,4-Dibromophenyl 4-nitrophenyl ether ................................................................................. 8111 

Dibutyltin dichloride ............................................................................................................... 8323 

Di-n-butyl phthalate ........................................................................................... 8061, 8270, 8410 

Dicamba............................................................................................................ 8085, 8151, 8321 

Dichlobenil (Casoron) ............................................................................................................ 8085 

Dichlone ...................................................................................................................... 8081, 8270 

Dichloran ............................................................................................................................... 8081 

3,4-Dichloroaniline ................................................................................................................ 8131 

1,2-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

1,3-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

1,4-Dichlorobenzene ............................................................ 8021, 8121, 8260, 8261, 8270, 8410 

3,3'-Dichlorobenzidine .................................................................................................. 8270,8325 

3,5-Dichlorobenzoic acid ............................................................................................. 8085, 8151 

2,3-Dichlorobiphenyl ............................................................................................................. 8082 

3,3'-Dichlorobiphenyl ............................................................................................................. 8275 

cis-1,4-Dichloro-2-butene ............................................................................................ 8260, 8261 

trans-1,4-Dichloro-2-butene ........................................................................................ 8260, 8261 

Dichlorodifluoromethane ................................................................................... 8021, 8260, 8261 

1,1-Dichloroethane ............................................................................................ 8021, 8260, 8261 

1,2-Dichloroethane ............................................................................................ 8021, 8260, 8261 

1,1-Dichloroethene (Vinylidene chloride) ........................................................... 8021, 8260, 8261 

cis-1,2-Dichloroethene ...................................................................................... 8021, 8260, 8261 

trans-1,2-Dichloroethene ................................................................................... 8021, 8260, 8261 

Dichlorofenthion .................................................................................................................... 8141 

Dichloromethane (DCM, Methylene chloride) .................................................... 8021, 8260, 8261 

2,6-Dichloro-4-nitroaniline ..................................................................................................... 8131 

2,3-Dichloronitrobenzene ...................................................................................................... 8091 

2,4-Dichloronitrobenzene ...................................................................................................... 8091 

3,5-Dichloronitrobenzene ...................................................................................................... 8091 

3,4-Dichloronitrobenzene ...................................................................................................... 8091 

2,5-Dichloronitrobenzene ...................................................................................................... 8091 

2,3-Dichlorophenol ................................................................................................................ 8041 

2,4-Dichlorophenol ............................................................................................ 8041, 8270, 8410 

2,5-Dichlorophenol ................................................................................................................ 8041 

2,6-Dichlorophenol ...................................................................................................... 8041, 8270 

3,4-Dichlorophenol ................................................................................................................ 8041 

3,5-Dichlorophenol ................................................................................................................ 8041 

2,4-Dichlorophenol 3-methyl-4-nitrophenyl ether ................................................................... 8111 

2,3-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,4-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,5-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

2,6-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

3,4-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

3,5-Dichlorophenyl 4-nitrophenyl ether .................................................................................. 8111 

Dichloroprop (Dichlorprop) ................................................................................ 8085, 8151, 8321 

1,2-Dichloropropane ......................................................................................... 8021, 8260, 8261 

1,3-Dichloropropane ......................................................................................... 8021, 8260, 8261 

2,2-Dichloropropane ......................................................................................... 8021, 8260, 8261 
SW-846 Update V TWO - 19 Revision 5 

October 2012

1,3-Dichloro-2-propanol .............................................................................................. 8021, 8260 

1,1-Dichloropropene ......................................................................................... 8021, 8260, 8261 

cis-1,3-Dichloropropene .................................................................................... 8021, 8260, 8261 

trans-1,3-Dichloropropene ................................................................................ 8021, 8260, 8261 

Dichlorovos (DDVP, Dichlorvos) ............................................................. 8085, 8141, 8270, 8321 

Dichlorprop (Dichloroprop) ................................................................................ 8085, 8151, 8321 

Dichlorvos (DDVP, Dichlorovos) ............................................................. 8085, 8141, 8270, 8321 

Dicrotophos ................................................................................................................. 8141, 8270 

Diclofol (Kelthane) ................................................................................................................ 8085 

Diclofop-methyl ................................................................................................................... 8085 

Dicofol ................................................................................................................................. 8081 

Dicyclohexyl phthalate .......................................................................................................... 8061 

Dieldrin ............................................................................................................. 8081, 8085, 8270 

1,2,3,4-Diepoxybutane .......................................................................................................... 8260 

Diesel range organics (DRO) ................................................................................................ 8015 

Diethylene glycol ................................................................................................................... 8430 

Diethyl ether ...................................................................................................... 8015, 8260, 8261 

Diethyl phthalate ............................................................................................... 8061, 8270, 8410 

Diethylstilbestrol .................................................................................................................... 8270 

Diethyl sulfate ....................................................................................................................... 8270 

Dihexyl phthalate .................................................................................................................. 8061 

Diisobutyl phthalate ............................................................................................................... 8061 

Diisopropyl ether (DIPE) ............................................................................................. 8015, 8261 

Dimethoate .............................................................................................. 8141, 8270,8085, 8321 

3,3'-Dimethoxybenzidine ............................................................................................. 8270, 8325 

Dimethylaminoazobenzene ................................................................................................... 8270 

2,5-Dimethylbenzaldehyde .................................................................................................... 8315 

7,12-Dimethylbenz(a)anthracene .......................................................................................... 8270 

3,3'-Dimethylbenzidine ................................................................................................ 8270, 8325 

4,4-Dimethyl-3-oxahexane (t-Amyl ethyl ether, TAEE) ................................................ 8015, 8261 

α,α-Dimethylphenethylamine ................................................................................................. 8270 

2,3-Dimethylphenol ............................................................................................................... 8041 

2,4-Dimethylphenol ..................................................................................................... 8041, 8270 

2,5-Dimethylphenol ............................................................................................................... 8041 

2,6-Dimethylphenol ............................................................................................................... 8041 

3,4-Dimethylphenol ............................................................................................................... 8041 

Dimethyl phthalate ............................................................................................ 8061, 8270, 8410 

Dinitramine ............................................................................................................................ 8091 

2,4-Dinitroaniline .................................................................................................................. 8131 

3,5-Dinitroaniline ................................................................................................................... 8095 

1,2-Dinitrobenzene ...................................................................................................... 8091, 8270 

1,3-Dinitrobenzene (1,3-DNB) ................................................................. 8091, 8095, 8270, 8330 

1,4-Dinitrobenzene ...................................................................................................... 8091, 8270 

4,6-Dinitro-2-methylphenol .......................................................................................... 8270, 8410 

2,4-Dinitrophenol ............................................................................................... 8041, 8270, 8410 

2,5-Dinitrophenol ................................................................................................................... 8041 

2,4-Dinitrotoluene (2,4-DNT) ..........................................................8091, 8095, 8270, 8330, 8410 

2,6-Dinitrotoluene (2,6-DNT) ..........................................................8091, 8095, 8270, 8330, 8410 

Dinocap................................................................................................................................. 8270 

Dinonyl phthalate .................................................................................................................. 8061 

Dinoseb (2-sec-Butyl-4,6-dinitrophenol, DNBP) .............................8041, 8085, 8151, 8270, 8321 
SW-846 Update V TWO - 20 Revision 5 

October 2012

Di-n-octyl phthalate ........................................................................................... 8061, 8270, 8410 

Dioxacarb .............................................................................................................................. 8318 

1,4-Dioxane ................................................................................................................ 8260, 8261 

Dioxathion ................................................................................................................... 8085, 8141 

Di-n-propyl phthalate ............................................................................................................. 8410 

DIPE (Diisopropyl ether) ............................................................................................. 8015, 8261 

Diphenamid ........................................................................................................................... 8085 

Diphenylamine ...................................................................................................................... 8270 

5,5-Diphenylhydantoin .......................................................................................................... 8270 

1,2-Diphenylhydrazine .......................................................................................................... 8270 

Diphenyltin dichloride ............................................................................................................ 8323 

Disperse Blue 3 ..................................................................................................................... 8321 

Disperse Blue 14 ................................................................................................................... 8321 

Disperse Brown 1 .................................................................................................................. 8321 

Disperse Orange 3 ................................................................................................................ 8321 

Disperse Orange 30 .............................................................................................................. 8321 

Disperse Red 1 ..................................................................................................................... 8321 

Disperse Red 5 ..................................................................................................................... 8321 

Disperse Red 13 ................................................................................................................... 8321 

Disperse Red 60 ................................................................................................................... 8321 

Disperse Yellow 5 ................................................................................................................. 8321 

Disulfoton ................................................................................................ 8085, 8141, 8270, 8321 

Diuron ............................................................................................................... 8085, 8321, 8325 

1,3-DNB (1,3-Dinitrobenzene) ................................................................. 8091, 8095, 8270, 8330 

DNBP (2-sec-Butyl-4,6-dinitrophenol, Dinoseb) .............................8041, 8085, 8151, 8270, 8321 

2,4-DNT (2,4-Dinitrotoluene) ..........................................................8091, 8095, 8270, 8330, 8410 

2,6-DNT (2,6-Dinitrotoluene) ................................................................... 8091, 8270, 8330, 8410 

EDB (1,2-Dibromoethane, Ethylene dibromide) ................................................. 8011, 8021, 8260 

Endosulfan I ...................................................................................................... 8081, 8085, 8270 

Endosulfan II ..................................................................................................... 8081, 8085, 8270 

Endosulfan sulfate ............................................................................................ 8081, 8085, 8270 

Endrin ............................................................................................................... 8081, 8085, 8270 

Endrin aldehyde ................................................................................................ 8081, 8085, 8270 

Endrin ketone .................................................................................................... 8081, 8085, 8270 

Epichlorohydrin ........................................................................................................... 8021, 8260 

EPN .................................................................................................................. 8141, 8085, 8270 

Eptam (EPTC)................................................................................................... 8085, 8141, 8321 

EPTC (Eptam)................................................................................................... 8085, 8141, 8321 

ETBE (Ethyl tert-butyl ether) ....................................................................................... 8015, 8261 

Ethalfluralin (Sonalan) ........................................................................................................... 8085 

Ethanol ............................................................................................................. 8015, 8260, 8261 

Ethion ............................................................................................................... 8085, 8141, 8270 

Ethoprop ..................................................................................................................... 8085, 8141 

Ethyl acetate ..................................................................................................... 8015, 8260, 8261 

Ethyl benzene ......................................................................................... 8015, 8021, 8260, 8261 

Ethyl carbamate .................................................................................................................... 8270 

Ethyl cyanide (Propionitrile)............................................................................... 8015, 8260, 8261 

Ethylene dibromide (EDB, 1,2-Dibromoethane) ................................................. 8011, 8021, 8260 

Ethylene glycol ...................................................................................................................... 8430 

Ethyl guthion (Azinphos-ethyl) ..................................................................................... 8085, 8141 

Ethylene oxide ............................................................................................................ 8015, 8260 
SW-846 Update V TWO - 21 Revision 5 

October 2012

Ethyl methacrylate ...................................................................................................... 8260, 8261 

Ethyl methanesulfonate ......................................................................................................... 8270 

Ethyl tert-butyl ether (ETBE) ....................................................................................... 8015, 8261 

Etridiazole ............................................................................................................................. 8081 

Famphur ........................................................................................................... 8141, 8270, 8321 

Fenamiphos .......................................................................................................................... 8085 

Fenarimol .............................................................................................................................. 8085 

Fenitrothion ................................................................................................................. 8085, 8141 

Fensulfothion .......................................................................................... 8085, 8141, 8270, 8321 

Fenthion ............................................................................................................ 8085, 8141, 8270 

Fenuron ................................................................................................................................ 8321 

Fluchloralin ........................................................................................................................... 8270 

Fluometuron .......................................................................................................................... 8321 

Fluoranthene ..................................................................................8100, 8270, 8275, 8310, 8410 

Fluorene.........................................................................................8100, 8270, 8275, 8310, 8410 

Fluridone ............................................................................................................................... 8085 

Fonophos .................................................................................................................... 8085, 8141 

Formaldehyde ....................................................................................................................... 8315 

Formetanate hydrochloride ......................................................................................... 8318, 8321 

Furaden (Carbofuran) ....................................................................................... 8270, 8318, 8321 

Gardona (Tetrachlovinphos, Stirophos) ............................................................... 80858141, 8270 

Garlon (Triclopyr) .................................................................................................................. 8085 

Gasoline range organics (GRO) ............................................................................................ 8015 

Guthion (Azinphos-methyl) ................................................................................ 8085, 8141, 8270 

Halowax-1000 ....................................................................................................................... 8081 

Halowax-1001 ....................................................................................................................... 8081 

Halowax-1013 ....................................................................................................................... 8081 

Halowax-1014 ....................................................................................................................... 8081 

Halowax-1051 ....................................................................................................................... 8081 

Halowax-1099 ....................................................................................................................... 8081 

Heptachlor ........................................................................................................ 8081, 8085, 8270 

2,2',3,3',4,4',5-Heptachlorobiphenyl ............................................................................ 8082, 8275 

2,2',3,4,4',5,5'-Heptachlorobiphenyl ............................................................................ 8082, 8275 

2,2',3,4,4',5',6-Heptachlorobiphenyl ...................................................................................... 8082 

2,2',3,4',5,5',6-Heptachlorobiphenyl ............................................................................ 8082, 8275 

Heptachlor epoxide ........................................................................................... 8081, 8085, 8270 

Heptanal ............................................................................................................................... 8315 

Hexachlorobenzene ............................................................. 8081, 8085, 8121, 8270, 8275, 8410 

2,2',3,3,4,4'-Hexachlorobiphenyl ........................................................................................... 8275 

2,2',3,4,4',5'-Hexachlorobiphenyl ................................................................................. 8082, 8275 

2,2',3,4,5,5'-Hexachlorobiphenyl ........................................................................................... 8082 

2,2',3,5,5',6-Hexachlorobiphenyl ........................................................................................... 8082 

2,2',4,4',5,5'-Hexachlorobiphenyl ........................................................................................... 8082 

Hexachlorobutadiene (1,3-Hexachlorobutadiene) ................ 8021, 8121, 8260, 8261, 8270, 8410 

α-Hexachlorocyclohexane (α-BHC) ......................................................... 8081, 8085, 8121, 8270 

β-Hexachlorocyclohexane (β-BHC) ......................................................... 8081, 8085, 8121, 8270 

δ-Hexachlorocyclohexane (δ-BHC) ......................................................... 8081, 8085, 8121, 8270 

γ-Hexachlorocyclohexane (γ-BHC, Lindane) ........................................... 8081, 8085, 8121, 8270 

Hexachlorocyclopentadiene ...........................................................8081, 8085, 8121, 8270, 8410 

Hexachloroethane ................................................................................... 8121, 8260, 8270, 8410 

Hexachlorophene .................................................................................................................. 8270 
SW-846 Update V TWO - 22 Revision 5 

October 2012

Hexachloropropene ..................................................................................................... 8141, 8270 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) .................................................... 8095, 8330, 8510 

Hexamethyl phosphoramide (HMPA) .................................................................................. , 8270 

Hexanal................................................................................................................................. 8315 

2-Hexanone ................................................................................................................ 8260, 8261 

Hexazinone ........................................................................................................................... 8085 

Hexyl 2-ethylhexyl phthalate ................................................................................................. 8061 

HMPA (Hexamethyl phosphoramide) .......................................................................... 8141, 8270 

HMX (Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine) ............................................... 8095, 8330 

1,2,3,4,6,7,8-HpCDD................................................................................................... 8280, 8290 

HpCDD, total ............................................................................................................... 8280, 8290 

1,2,3,4,6,7,8-HpCDF ................................................................................................... 8280, 8290 

1,2,3,4,7,8,9-HpCDF ................................................................................................... 8280, 8290 

HpCDF, total ............................................................................................................... 8280, 8290 

1,2,3,4,7,8-HxCDD ...................................................................................................... 8280, 8290 

1,2,3,6,7,8-HxCDD ...................................................................................................... 8280, 8290 

1,2,3,7,8,9-HxCDD ...................................................................................................... 8280, 8290 

HxCDD, total ............................................................................................................... 8280, 8290 

1,2,3,4,7,8-HxCDF ...................................................................................................... 8280, 8290 

1,2,3,6,7,8-HxCDF ...................................................................................................... 8280, 8290 

1,2,3,7,8,9-HxCDF ...................................................................................................... 8280, 8290 

2,3,4,6,7,8-HxCDF ...................................................................................................... 8280, 8290 

HxCDF ........................................................................................................................ 8280, 8290 

Hydroquinone ....................................................................................................................... 8270 

3-Hydroxycarbofuran................................................................................................... 8318, 8321 

5-Hydroxydicamba ................................................................................................................ 8151 

2-Hydroxypropionitrile ........................................................................................................... 8260 

Igran (Terbutryn) ................................................................................................................... 8085 

Imidan (Phosmet) .............................................................................................. 8085, 8141, 8270 

Indeno(1,2,3-cd)pyrene ........................................................................... 8100, 8270, 8275, 8310 

Iodomethane (Methyl iodide) ....................................................................................... 8260, 8261 

Ioxynil ................................................................................................................................... 8085 

Isobutyl alcohol (2-Methyl-1-propanol) ........................................................................ 8260, 8261 

Isodrin ......................................................................................................................... 8081, 8270 

Isophorone .................................................................................................................. 8270, 8410 

Isopropalin ............................................................................................................................ 8091 

Isopropyl alcohol (2-Propanol) .................................................................................... 8015, 8260 

Isopropylbenzene ........................................................................................................ 8021, 8260 

p-Isopropyltoluene ............................................................................................ 8021, 8260, 8261 

Isosafrole .............................................................................................................................. 8270 

Isovaleraldehyde ................................................................................................................... 8315 

Kelthane (Diclofol) ................................................................................................................. 8085 

Kepone ................................................................................................................................. 8270 

Kerb (Pronamide) ...................................................................................................... 8085, 8270 

Lannate (Methomyl) .................................................................................................... 8318, 8321 

Leptophos ................................................................................................................... 8141, 8270 

Lindane (γ-Hexachlorocyclohexane, γ-BHC) ........................................... 8081, 8085, 8121, 8270 

Linuron (Lorox)............................................................................................................ 8321, 8325 

Lorox (Linuron)............................................................................................................ 8321, 8325 

Malathion ......................................................................................................... 8085, 8141, 8270 

Maleic anhydride ................................................................................................................... 8270 
SW-846 Update V TWO - 23 Revision 5 

October 2012

Malononitrile ......................................................................................................................... 8260 

MCPA ......................................................................................................................... 8151, 8321 

MCPA (acid) ......................................................................................................................... 8085 

MCPP ......................................................................................................................... 8151, 8321 

MCPP (acid) ......................................................................................................................... 8085 

MEK (Methyl ethyl ketone, 2-Butanone) ............................................................ 8015, 8260, 8261 

Merphos ............................................................................................................ 8085, 8141, 8321 

Mestranol .............................................................................................................................. 8270 

Mesurol (Methiocarb) ........................................................................................ 8141, 8318, 8321 

Methacrylonitrile .......................................................................................................... 8260, 8261 

Metalaxyl ............................................................................................................................... 8085 

Methanol ..................................................................................................................... 8015, 8260 

Methapyrilene ....................................................................................................................... 8270 

Methiocarb (Mesurol) ........................................................................................ 8141, 8318, 8321 

Methomyl (Lannate) .................................................................................................... 8318, 8321 

Methoxychlor .................................................................................................... 8081, 8085, 8270 

Methyl acrylate ...................................................................................................................... 8260 

Methyl chlorpyrifos ................................................................................................................ 8085 

Methyl-tert-butyl ether (MTBE) .......................................................................... 8015, 8260, 8261 

3-Methylcholanthrene.................................................................................................. 8100, 8270 

2-Methyl-4,6-dinitrophenol .................................................................................................... 8041 

4,4'-Methylenebis(2-chloroaniline) ......................................................................................... 8270 

4,4'-Methylenebis(N,N-dimethylaniline) ................................................................................. 8270 

Methyl ethyl ketone (MEK, 2-Butanone) ............................................................ 8015, 8260, 8261 

Methylene chloride (Dichloromethane, DCM) .................................................... 8021, 8260, 8261 

Methyl iodide (Iodomethane) ....................................................................................... 8260, 8261 

Methyl isobutyl ketone (MIBK, 4-Methyl-2-pentanone) ................................................ 8260, 8261 

Methyl methacrylate .................................................................................................... 8260, 8261 

Methyl methanesulfonate ...................................................................................................... 8270 

1-Methylnaphthalene............................................................................................................. 8261 

2-Methylnaphthalene......................................................................................... 8261, 8270, 8410 

Methyl paraoxon ................................................................................................................... 8085 

Methyl parathion (Parathion, methyl) ....................................................... 8085, 8270, 8141, 8321 

4-Methyl-2-pentanone (MIBK, Methyl isobutyl ketone) ................................................ 8260, 8261 

2-Methylphenol (o-Cresol) ................................................................................. 8041, 8270, 8410 

3-Methylphenol (m-Cresol) .......................................................................................... 8041, 8270 

4-Methylphenol (p-Cresol) ................................................................................. 8041, 8270, 8410 

2-Methyl-1-propanol (Isobutyl alcohol) ........................................................................ 8260, 8261 

2-Methyl-2-propanol (t-Butyl alcohol) .......................................................................... 8015, 8260 

2-Methylpyridine (2-Picoline) ..................................................................... 8015, 8260, 82618270 

Methyl-2,4,6-trinitrophenyl-nitramine (Tetryl) ......................................................................... 8330 

Metolachlor ........................................................................................................................... 8085 

Metolcarb .................................................................................................................... 8318, 8321 

Metribuzin ............................................................................................................................. 8085 

Mevinphos ........................................................................................................ 8085, 8141, 8270 

Mexacarbate ..................................................................................................... 8270, 8318, 8321 

MGK-264 .............................................................................................................................. 8085 

MIBK (Methyl isobutyl ketone, 4-Methyl-2-pentanone) ................................................ 8260, 8261 

Mirex ................................................................................................................. 8081, 8085, 8270 

Molinate ............................................................................................................ 8085, 8141, 8321 

Monobutyltin trichloride ......................................................................................................... 8323 
SW-846 Update V TWO - 24 Revision 5 

October 2012

Monocrotophos ................................................................................................. 8141, 8270, 8321 

Monophenyltin trichloride ...................................................................................................... 8323 

Monuron...................................................................................................................... 8321, 8325 

MTBE (Methyl-tert-butyl ether) .......................................................................... 8015, 8260, 8261 

Naled ................................................................................................................ 8141, 8270, 8321 

Naphthalene .................................................... 8021, 8100, 8260, 8261, 8270, 8275, 8310, 8410 

Napropamide ........................................................................................................................ 8085 

NB (Nitrobenzene) ............................................................... 8091, 8095, 8260, 8270, 8330, 8410 

1,2-Naphthoquinone ............................................................................................................. 8091 

1,4-Naphthoquinone ................................................................................................... 8270, 8091 

1-Naphthylamine ................................................................................................................... 8270 

2-Naphthylamine ................................................................................................................... 8270 

Neburon ................................................................................................................................ 8321 

Nicotine ................................................................................................................................. 8270 

5-Nitroacenaphthene............................................................................................................. 8270 

2-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

3-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

4-Nitroaniline ..................................................................................................... 8131, 8270, 8410 

5-Nitro-o-anisidine ................................................................................................................. 8270 

Nitrobenzene (NB) ............................................................... 8091, 8095, 8260, 8270, 8330, 8410 

4-Nitrobiphenyl ...................................................................................................................... 8270 

Nitrofen ....................................................................................................................... 8081, 8270 

Nitroglycerin ................................................................................................................ 8095, 8332 

2-Nitrophenol ................................................................................................... 8041, 8270, 8410 

3-Nitrophenol ....................................................................................................................... 8041 

4-Nitrophenol .................................................................................8041, 8085, 8151, 8270, 8410 

4-Nitrophenyl phenyl ether .................................................................................................... 8111 

2-Nitropropane ...................................................................................................................... 8260 

Nitroquinoline-1-oxide ........................................................................................................... 8270 

N-Nitroso-di-n-butylamine (N-Nitrosodibutylamine) ................................. 8015, 8260, 8261, 8270 

N-Nitrosodiethylamine ................................................................................................. 8261, 8270 

N-Nitrosodimethylamine .......................................................................... 8070, 8261, 8270, 8410 

N-Nitrosodiphenylamine .................................................................................... 8070, 8270, 8410 

N-Nitroso-di-n-propylamine ..................................................................... 8070, 8261, 8270, 8410 

N-Nitrosomethylethylamine ......................................................................................... 8261, 8270 

N-Nitrosomorpholine ............................................................................................................. 8270 

N-Nitrosopiperidine ............................................................................................................... 8270 

N-Nitrosopyrrolidine .............................................................................................................. 8270 

2-Nitrotoluene (o-Nitrotoluene, 2-NT) ................................................................ 8091, 8095, 8330

3-Nitrotoluene (m-Nitrotoluene, 3-NT) ............................................................... 8091, 8095, 8330 

4-Nitrotoluene (p-Nitrotoluene, 4-NT) ................................................................ 8091, 8095, 8330

o-Nitrotoluene (2-Nitrotoluene, 2-NT) ................................................................ 8091, 8095, 8330 

m-Nitrotoluene (3-Nitrotoluene, 3-NT) ............................................................... 8091, 8095, 8330 

p-Nitrotoluene (4-Nitrotoluene, 4-NT) ................................................................ 8091, 8095, 8330 

5-Nitro-o-toluidine ................................................................................................................. 8270 

trans-Nonachlor .................................................................................................................... 8081 

2,2'3,3'4,4'5,5'6-Nonachlorobiphenyl ........................................................................... 8082, 8275 

Nonanal ................................................................................................................................ 8315 

Norflurazon ........................................................................................................................... 8085 

2-NT (2-Nitrotoluene, o-Nitrotoluene) ................................................................ 8091, 8095, 8330 

3-NT (3-Nitrotoluene, m-Nitrotoluene) ............................................................... 8091, 8095, 8330 
SW-846 Update V TWO - 25 Revision 5 

October 2012

4-NT (4-Nitrotoluene, p-Nitrotoluene) ................................................................ 8091, 8095, 8330 

OCDD ......................................................................................................................... 8280, 8290 

OCDF ......................................................................................................................... 8280, 8290 

2,2',3,3',4,4'5,5'-Octachlorobiphenyl ...................................................................................... 8275 

Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) ............................................... 8095, 8330 

Octamethyl pyrophosphoramide ........................................................................................... 8270 

Octanal ................................................................................................................................. 8315 

Oxamyl ...................................................................................................................... 8318, 8321 

4,4'-Oxydianiline ................................................................................................................... 8270 

Oxyfluorfen ........................................................................................................................... 8085 

Paraldehyde ................................................................................................................ 8015, 8260 

Parathion .................................................................................................................... 8085, 8270 

Parathion, ethyl ..................................................................................................................... 8141 

Parathion, methyl .................................................................................... 8085, 8270, 8141, 8321 

PCB-1016 (Aroclor-1016) ............................................................................................ 8082, 8270 

PCB-1221 (Aroclor-1221) ............................................................................................ 8082, 8270 

PCB-1232 (Aroclor-1232) ............................................................................................ 8082, 8270 

PCB-1242 (Aroclor-1242) ............................................................................................ 8082, 8270 

PCB-1248 (Aroclor-1248) ............................................................................................ 8082, 8270 

PCB-1254 (Aroclor-1254) ............................................................................................ 8082, 8270 

PCB-1260 (Aroclor-1260) ............................................................................................ 8082, 8270 

PCBs, as congeners ............................................................................................................. 8082 

PCNB (Pentachloronitrobenzene) ..................................................................... 8081, 8091, 8270 

Pebulate............................................................................................................ 8085, 8141, 8321 

1,2,3,7,8-PeCDD ......................................................................................................... 8280, 8290 

PeCDD, total ............................................................................................................... 8280, 8290 

1,2,3,7,8-PeCDF ......................................................................................................... 8280, 8290 

2,3,4,7,8-PeCDF ......................................................................................................... 8280, 8290 

PeCDF, total ............................................................................................................... 8280, 8290 

Pendimethaline (Penoxalin) ........................................................................................ 8085, 8091 

Penoxalin (Pendimethaline) ........................................................................................ 8085, 8091 

Pentachlorobenzene ................................................................................................... 8121, 8270 

2,2',3,4,5'-Pentachlorobiphenyl ............................................................................................. 8082 

2,3',4,4',5-Pentachlorobiphenyl ............................................................................................. 8275 

2,2',4,5,5'-Pentachlorobiphenyl ................................................................................... 8082, 8275 

2,3,3',4',6-Pentachlorobiphenyl ............................................................................................. 8082 

Pentachloroethane ...................................................................................................... 8260, 8261 

Pentachloronitrobenzene (PCNB) ..................................................................... 8081, 8091, 8270 

Pentachlorophenol .........................................................................8041, 8085, 8151, 8270, 8410 

Pentaerythritoltetranitrate ...................................................................................................... 8095 

Pentafluorobenzene .............................................................................................................. 8260 

Pentanal (Valeraldehyde) ...................................................................................................... 8315 

2-Pentanone ............................................................................................................... 8015, 8260 

Perchloroethylene (Tetrachloroethene, Tetrachloroethylene) ............................ 8021, 8260, 8261 

Permethrin (cis + trans) ......................................................................................................... 8081 

Perthane ............................................................................................................................... 8081 

Phenacetin ............................................................................................................................ 8270 

Phenanthrene ................................................................................8100, 8270, 8275, 8310, 8410 

Phenobarbital ........................................................................................................................ 8270 

Phenol .............................................................................................................. 8041, 8270, 8410 

1,4-Phenylenediamine .......................................................................................................... 8270 
SW-846 Update V TWO - 26 Revision 5 

October 2012

1,2-Phenylenediamine (o-Phenylenediamine) ............................................................. 8141, 8321 

Phorate ................................................................................................... 8085, 8141, 8270, 8321 

Phosalone ............................................................................................................................. 8270 

Phosmet (Imidan) .............................................................................................. 8085, 8141, 8270 

Phosphamidon .................................................................................................. 8085, 8141, 8270 

Phthalic anhydride ................................................................................................................ 8270 

Physostigmine....................................................................................................................... 8321 

Physostigmine salicylate ....................................................................................................... 8321 

Picloram ...................................................................................................................... 8085, 8151 

2-Picoline (2-Methylpyridine) ................................................................... 8015, 8260, 8261, 8270 

Piperonyl sulfoxide ................................................................................................................ 8270 

Polychlorinated biphenyls (PCBs), as Aroclors or congeners ..................................... 8082, 8270 

Profluralin .................................................................................................................... 8085, 8091 

Pramitol 5p (Prometon) ......................................................................................................... 8085 

Promecarb .................................................................................................................. 8318, 8321 

Prometon (Pramitol 5p) ......................................................................................................... 8085 

Prometryn ............................................................................................................................. 8085 

Pronamide (Kerb) ....................................................................................................... 8085, 8270 

Propachlor (Ramrod)................................................................................................... 8081, 8085 

Propanal (Propionaldehyde) .................................................................................................. 8315 

1-Propanol (n-Propyl alcohol) ...................................................................................... 8015, 8260 

2-Propanol (Isopropyl alcohol) ................................................................................... 8015, 8260 

Propargite (S-181) ................................................................................................................ 8085 

Propargyl alcohol .................................................................................................................. 8260 

Propazine .............................................................................................................................. 8085 

Propenal (Acrolein) ........................................................................8015, 8260, 8261, 8315, 8316 

Propetamidophos .................................................................................................................. 8085 

Propham ..................................................................................................................... 8141, 8321 

ß-Propiolactone ..................................................................................................................... 8260 

Propionaldehyde (Propanal).................................................................................................. 8315 

Propionitrile (Ethyl cyanide) .............................................................................. 8015, 8260, 8261 

Propoxur (Baygon) ...................................................................................................... 8318, 8321 

n-Propylalcohol (1-Propanol) ....................................................................................... 8015, 8260 

n-Propylamine ....................................................................................................................... 8260 

n-Propylbenzene ............................................................................................... 8021, 8260, 8261 

Propylthiouracil ..................................................................................................................... 8270 

Prosulfocarb ................................................................................................................ 8141, 8321 

Prothiophos (Tokuthion) ........................................................................................................ 8141 

Pyrene ...........................................................................................8100, 8270, 8275, 8310, 8410 

Pyridine ............................................................................................................. 8015, 8260, 8261 

Ramrod (Propachlor ) ............................................................................................................ 8085 

RDX (Hexahydro-1,3,5-trinitro-1,3,5-triazine) .............................................................. 8095, 8330 

Resorcinol ............................................................................................................................. 8270 

Ronnel ........................................................................................................................ 8085, 8141 

Rotenone .............................................................................................................................. 8325 

S-181 (Propargite) ................................................................................................................ 8085 

Safrole .................................................................................................................................. 8270 

Sevin (Carbaryl) ...................................................................................... 8270, 8318, 8321, 8325 

Siduron ....................................................................................................................... 8321, 8325 

Simazine ..................................................................................................................... 8085, 8141 

Silvex (2,4,5-TP) ............................................................................................... 8085, 8151, 8321 
SW-846 Update V TWO - 27 Revision 5 

October 2012

Solvent Red 3 ....................................................................................................................... 8321 

Solvent Red 23 ..................................................................................................................... 8321 

Sonalan (Ethalfluralin) ........................................................................................................... 8085 

Stirophos (Tetrachlorvinphos, Gardona)............................................................ 8085, 8141, 8270 

Strobane ............................................................................................................................... 8081 

Strychnine ............................................................................................................................. 8270 

Styrene ............................................................................................................. 8021, 8260, 8261 

Sulfallate ............................................................................................................................... 8270 

Sulfotepp ..................................................................................................................... 8085, 8141 

Sulprofos (Bolstar) ...................................................................................................... 8085, 8141 

2,4,5-T ........................................................................................................................ 8151, 8321 

2,4,5-T (acid) ........................................................................................................................ 8085 

2,4,5-TB ................................................................................................................................ 8085 

TAA (t-Amyl alcohol) ............................................................................................................. 8015 

TAEE (t-Amyl ethyl ether, 4,4-Dimethyl-3-oxahexane) ................................................ 8015, 8261 

TAME (t-Amyl methyl ether) ........................................................................................ 8015, 8261 

2,4,5-T, butoxyethanol ester.................................................................................................. 8321 

2,4,5-T, butyl ester ................................................................................................................ 8321 

2,3,7,8-TCDD .............................................................................................................. 8280, 8290 

TCDD, total ................................................................................................................. 8280, 8290 

2,3,7,8-TCDF .............................................................................................................. 8280, 8290 

TCDF, total ................................................................................................................. 8280, 8290 

Tebuthiuron ................................................................................................................. 8085, 8321 

Temephos (Abate) ................................................................................................................ 8085 

Temik (Aldicarb) .......................................................................................................... 8318, 8321 

TEPP (Tetraethyl pyrophosphate) ............................................................................... 8141, 8270 

Terbacil ................................................................................................................................. 8085 

Terbufos...................................................................................................................... 8141, 8270 

Terbutryn (Igran) ................................................................................................................... 8085 

1,2,3,4-Tetrachlorobenzene .................................................................................................. 8121 

1,2,3,5-Tetrachlorobenzene .................................................................................................. 8121 

1,2,4,5-Tetrachlorobenzene ........................................................................................ 8121, 8270 

2,2',3,5'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

2,2',4,5'-Tetrachlorobiphenyl ................................................................................................. 8275 

2,2',5,5'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

2,3',4,4'-Tetrachlorobiphenyl ....................................................................................... 8082, 8275 

1,1,1,2-Tetrachloroethane ........................................................................................... 8021, 8260 

1,1,2,2-Tetrachloroethane ................................................................................. 8021, 8260, 8261 

Tetrachloroethene (Perchloroethylene, Tetrachloroethylene) ............................ 8021, 8260, 8261 

2,3,4,5-Tetrachloronitrobenzene ........................................................................................... 8091 

2,3,5,6-Tetrachloronitrobenzene ........................................................................................... 8091 

2,3,4,5-Tetrachlorophenol ........................................................................................... 8041, 8085 

2,3,4,6-Tetrachlorophenol ................................................................................. 8041, 8085, 8270 

2,3,5,6-Tetrachlorophenol ..................................................................................................... 8041 

Tetrachlorvinphos (Stirophos, Gardona)............................................................ 8085, 8141, 8270 

Tetraethyl dithiopyrophosphate ............................................................................................. 8270 

Tetraethyl pyrophosphate (TEPP) ............................................................................... 8141, 8270 

Tetrahydrofuran (THF) .......................................................................................................... 8261 

THF (Tetrahydrofuran) .......................................................................................................... 8261 

Tetrazene .............................................................................................................................. 8331 

Tetryl (Methyl-2,4,6-trinitrophenylnitramine) .......................................................................... 8330 
SW-846 Update V TWO - 28 Revision 5 

October 2012

Thiodicarb ................................................................................................................... 8318, 8321 

Thiofanox .............................................................................................................................. 8321 

Thiophanate-methyl .............................................................................................................. 8321 

Thionazin (Zinophos) .................................................................................................. 8141, 8270 

Thiophenol (Benzenethiol) .................................................................................................... 8270 

1,3,5-TNB (1,3,5-Trinitrobenzene) ..................................................................... 8095, 8270, 8330 

2,4,6-TNT (2,4,6-Trinitrotoluene) ................................................................................. 8095, 8330 

TOCP (Tri-o-cresylphosphate) .............................................................................................. 8141 

Tokuthion (Prothiofos) ........................................................................................................... 8141 

m-Tolualdehyde .................................................................................................................... 8315 

o-Tolualdehyde ..................................................................................................................... 8315 

p-Tolualdehyde ..................................................................................................................... 8315 

Toluene ................................................................................................... 8015, 8021, 8260, 8261 

Toluene diisocyanate ............................................................................................................ 8270 

o-Toluidine .............................................................................................. 8015, 8260, 8261, 8270 

Toxaphene ........................................................................................................ 8081, 8270, 8272 

2,4,5-TP (Silvex) ............................................................................................... 8085, 8151, 8321 

Treflan (Trifluralin) ................................................................................... 8081, 8085, 8091, 8270 

Triademefon .......................................................................................................................... 8085 

Triallate ............................................................................................................. 8085, 8141, 8321 

Tributyltin chloride ................................................................................................................. 8323 

Triclopyr (Garlon) .................................................................................................................. 8085 

Trichlorfon ................................................................................................................... 8141, 8321 

2,4,6-Trichloroaniline............................................................................................................. 8131 

2,4,5-Trichloroaniline............................................................................................................. 8131 

1,2,3-Trichlorobenzene ........................................................................... 8021, 8121, 8260, 8261 

1,2,4-Trichlorobenzene .............................................. 8021, 8121, 8260, 8261, 8270, 8275, 8410 

1,3,5-Trichlorobenzene ......................................................................................................... 8121 

2,2',5-Trichlorobiphenyl ............................................................................................... 8082, 8275 

2,3',5-Trichlorobiphenyl ......................................................................................................... 8275 

2,4',5-Trichlorobiphenyl ............................................................................................... 8082, 8275 

1,1,1-Trichloroethane ........................................................................................ 8021, 8260, 8261 

1,1,2-Trichloroethane ........................................................................................ 8021, 8260, 8261 

Trichloroethene (Trichloroethylene) ......................................................... 8021, 8260, 8261, 8535 

Trichlorofluoromethane ..................................................................................... 8021, 8260, 8261 

Trichloronate ......................................................................................................................... 8141 

1,2,3-Trichloro-4-nitrobenzene .............................................................................................. 8091 

1,2,4-Trichloro-5-nitrobenzene .............................................................................................. 8091 

2,4,6-Trichloronitrobenzene .................................................................................................. 8091 

2,3,4-Trichlorophenol ............................................................................................................ 8041 

2,3,5-Trichlorophenol ............................................................................................................ 8041 

2,3,6-Trichlorophenol ............................................................................................................ 8041 

2,4,5-Trichlorophenol .............................................................................. 8041, 8085, 8270, 8410 

2,4,6-Trichlorophenol .............................................................................. 8041, 8085, 8270, 8410 

2,3,4-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,3,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,3,6-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,4,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

2,4,6-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

3,4,5-Trichlorophenyl 4-nitrophenyl ether .............................................................................. 8111 

1,2,3-Trichloropropane ...................................................................................... 8021, 8260, 8261 
SW-846 Update V TWO - 29 Revision 5 

October 2012

Tri-o-cresylphosphate (TOCP) .............................................................................................. 8141 

Triethylamine ........................................................................................................................ 8015 

O,O,O-Triethyl phosphorothioate .......................................................................................... 8270 

Trifluralin (Treflan) ................................................................................... 8081, 8085, 8091, 8270 

Trihalomethanes ................................................................................................................... 8535 

2,4,5-Trimethylaniline ............................................................................................................ 8270 

1,2,4-Trimethylbenzene .................................................................................... 8021, 8260, 8261 

1,3,5-Trimethylbenzene .................................................................................... 8021, 8260, 8261 

Trimethyl phosphate ............................................................................................................. 8270 

1,3,5-Trinitrobenzene (1,3,5-TNB)..................................................................... 8095, 8270, 8330 

2,4,6-Trinitrophenylmethylnitramine ...................................................................................... 8095 

2,4,6-Trinitrotoluene (2,4,6-TNT) ................................................................................. 8095, 8330 

Triphenyltin chloride .............................................................................................................. 8323 

Tris-BP (Tris(2,3-dibromopropyl) phosphate) .............................................................. 8270, 8321 

Tri-p-tolyl phosphate ............................................................................................................. 8270 

Tris(2,3-dibromopropyl) phosphate (Tris-BP) .............................................................. 8270, 8321 

Valeraldehyde (Pentanal) ...................................................................................................... 8315 

Vernolate .............................................................................................................................. 8085 

Vinyl acetate ......................................................................................................................... 8260 

Vinyl chloride .................................................................................................... 8021, 8260, 8261 

Vinylidene chloride (1,1-Dichloroethene) ........................................................... 8021, 8260, 8261 

m-Xylene ................................................................................................. 8015, 8021, 8260, 8261

o-Xylene.................................................................................................. 8015, 8021, 8260, 8261 

p-Xylene.................................................................................................. 8015, 8021, 8260, 8261 

Zinophos (Thionazin) .................................................................................................. 8141, 8270 

 
SW-846 Update V TWO - 30 Revision 5 

October 2012

TABLE 2-2 

 METHOD 8011 (MICROEXTRACTION AND GAS CHROMATOGRAPHY) 

1,2-Dibromo-3-chloropropane (DBCP) 

1,2-Dibromoethane (EDB) 

TABLE 2-3 

 METHOD 8015 (GC/FID) - NONHALOGENATED VOLATILES 

Acetone Ethyl tert-butyl ether (ETBE) 

Acetonitrile Gasoline range organics (GRO) 

Acrolein Isopropyl alcohol 

Acrylonitrile Methanol 

Allyl alcohol Methyl ethyl ketone (MEK, 2-

Butanone) 

t-Amyl alcohol (TAA) N-Nitroso-di-n-butylamine 

t-Amyl ethyl ether (TAEE) Paraldehyde 

t-Amyl methyl ether (TAME) 2-Pentanone 

Benzene 2-Picoline 

t-Butyl alcohol 1-Propanol (n-Propyl alcohol) 

Crotonaldehyde Propionitrile 

Diesel range organics (DRO) Pyridine 

Diethyl ether Toluene 

Diisopropyl ether (DIPE) o-Toluidine 

Ethanol o-Xylene 

Ethyl acetate m-Xylene 

Ethyl benzene p-Xylene 

Ethylene oxide Triethylamine 
SW-846 Update V TWO - 31 Revision 5 

October 2012

TABLE 2-4 

 METHOD 8021 (GC, PHOTOIONIZATION AND ELECTROLYTIC 

 CONDUCTIVITY DETECTORS) - AROMATIC AND HALOGENATED VOLATILES 

Allyl chloride cis-1,2-Dichloroethene 

Benzene trans-1,2-Dichloroethene 

Benzyl chloride 1,2-Dichloropropane 

Bis(2-chloro-1-methylethyl) ether 1,3-Dichloropropane 

Bromoacetone 2,2-Dichloropropane 

Bromobenzene 1,3-Dichloro-2-propanol 

Bromochloromethane 1,1-Dichloropropene 

Bromodichloromethane cis-1,3-Dichloropropene 

Bromoform trans-1,3-Dichloropropene 

Bromomethane Epichlorhydrin 

n-Butylbenzene Ethylbenzene 

sec-Butylbenzene Hexachlorobutadiene 

tert-Butylbenzene Isopropylbenzene 

Carbon tetrachloride p-Isopropyltoluene 

Chlorobenzene Methylene chloride 

Chlorodibromomethane Naphthalene 

Chloroethane n-Propylbenzene 

2-Chloroethanol Styrene 

2-Chloroethyl vinyl ether 1,1,1,2-Tetrachloroethane

Chloroform 1,1,2,2-Tetrachloroethane 

Chloromethyl methyl ether Tetrachloroethene 

Chloroprene Toluene 

Chloromethane 1,2,3-Trichlorobenzene 

2-Chlorotoluene 1,2,4-Trichlorobenzene 

4-Chlorotoluene 1,1,1-Trichloroethane 

1,2-Dibromo-3-chloropropane 1,1,2-Trichloroethane 

1,2-Dibromoethane Trichloroethene 

Dibromomethane Trichlorofluoromethane 

1,2-Dichlorobenzene 1,2,3-Trichloropropane 

1,3-Dichlorobenzene 1,2,4-Trimethylbenzene 

1,4-Dichlorobenzene 1,3,5-Trimethylbenzene 

Dichlorodifluoromethane Vinyl chloride 

1,1-Dichloroethane o-Xylene 

1,2-Dichloroethane m-Xylene 

1,1-Dichloroethene p-Xylene 
SW-846 Update V TWO - 32 Revision 5 

October 2012

TABLE 2-5 

 METHODS 8031 AND 8033 (GC WITH NITROGEN-PHOSPHORUS DETECTION) 

 AND METHOD 8032 (GC WITH ELECTRON CAPTURE DETECTION) 

Method 8031: Acrylonitrile 

Method 8032: Acrylamide 

Method 8033: Acetonitrile 

TABLE 2-6 

 METHOD 8041 (GC) - PHENOLS 

2-Chloro-5-methylphenol 2,5-Dinitrophenol 

4-Chloro-2-methylphenol Dinoseb (2-sec-butyl-4,6-dinitro phenol) 

4-Chloro-3-methylphenol 2-Methyl-4,6-dinitrophenol 

2-Chlorophenol 2-Methylphenol (o-Cresol) 

3-Chlorophenol 4-Methylphenol (p-Cresol) 

4-Chlorophenol 2-Nitrophenol 

2-Cyclohexyl-4,6-dinitrophenol 3-Nitrophenol 

2,3-Dichlorophenol 4-Nitrophenol 

2,4-Dichlorophenol Pentachlorophenol 

2,5-Dichlorophenol Phenol 

2,6-Dichlorophenol 2,3,4,5-Tetrachlorophenol 

3,4-Dichlorophenol 2,3,4,6-Tetrachlorophenol 

3,5-Dichlorophenol 2,3,5,6-Tetrachlorophenol 

2,3-Dimethylphenol 2,3,4-Trichlorophenol 

2,4-Dimethylphenol 2,3,5-Trichlorophenol 

2,5-Dimethylphenol 2,3,6-Trichlorophenol 

2,6-Dimethylphenol 2,4,5-Trichlorophenol 

3,4-Dimethylphenol 2,4,6-Trichlorophenol 

2,4-Dinitrophenol 

 
SW-846 Update V TWO - 33 Revision 5 

October 2012

TABLE 2-7 

METHOD 8061 (GC/ECD) - PHTHALATE ESTERS 

Benzyl benzoate Dihexyl phthalate 

Bis(2-n-butoxyethyl) phthalate Diisobutyl phthalate 

Bis(2-ethoxyethyl) phthalate Di-n-butyl phthalate 

Bis(2-ethylhexyl) phthalate Diethyl phthalate 

Bis(2-methoxyethyl) phthalate Dinonyl phthalate 

Bis(4-methyl-2-pentyl)-phthalate Dimethyl phthalate

Butyl benzyl phthalate Di-n-octyl phthalate 

Diamyl phthalate Hexyl 2-ethylhexyl phthalate 

Dicyclohexyl phthalate 

TABLE 2-8 

METHOD 8070 (GC) - NITROSAMINES 

N-Nitrosodimethylamine 

N-Nitrosodiphenylamine 

N-Nitrosodi-n-propylamine 
SW-846 Update V TWO - 34 Revision 5 

October 2012

TABLE 2-9 

METHOD 8081 (GC) - ORGANOCHLORINE PESTICIDES 

Alachlor Diallate Hexachlorobenzene 

Aldrin Dichlone Hexachlorocyclopentadiene 

α-BHC Dichloran Isodrin 

β-BHC Dicofol Methoxychlor 

δ-BHC Dieldrin Mirex 

γ-BHC (Lindane) Endosulfan I Nitrofen 

Captafol Endosulfan II trans-Nonachlor 

Carbophenothion Endosulfan sulfate Pentachloronitrobenzene (PCNB) 

cis-Chlordane Endrin Permethrin (cis + trans) 

trans-Chlordane Endrin aldehyde Perthane 

Chlordane (NOS) Endrin ketone Propachlor 

Chlorobenzilate Etridiazole Strobane 

Chloroneb Halowax-1000 Toxaphene 

Chloropropylate Halowax-1001 Trifluralin 

Chlorothalonil Halowax-1013 

DBCP Halowax-1014 

Dacthal (DCPA) Halowax-1051 

4,4'-DDD Halowax-1099 

4,4'-DDE Heptachlor 

4,4'-DDT Heptachlor epoxide 
SW-846 Update V TWO - 35 Revision 5 

October 2012

TABLE 2-10 

METHOD 8082 (GC) - POLYCHLORINATED BIPHENYLS 

Aroclor 1016 2,3',4,4'-Tetrachlorobiphenyl 

Aroclor 1221 2,2',3,4,5'-Pentachlorobiphenyl 

Aroclor 1232 2,2',4,5,5'-Pentachlorobiphenyl 

Aroclor 1242 2,3,3',4',6-Pentachlorobiphenyl 

Aroclor 1248 2,2',3,4,4',5'-Hexachlorobiphenyl 

Aroclor 1254 2,2',3,4,5,5'-Hexachlorobiphenyl 

Aroclor 1260 2,2',3,5,5',6-Hexachlorobiphenyl 

PCBs as congeners 2,2',4,4',5,5'-Hexachlorobiphenyl

2-Chlorobiphenyl 2,2',3,3',4,4',5-Heptachlorobiphenyl 

2,3-Dichlorobiphenyl 2,2',3,4,4',5,5'-Heptachlorobiphenyl 

2,2',5-Trichlorobiphenyl 2,2',3,4,4',5',6-Heptachlorobiphenyl 

2,4',5-Trichlorobiphenyl 2,2',3,4',5,5',6-Heptachlorobiphenyl 

2,2',3,5'-Tetrachlorobiphenyl 2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl 

2,2',5,5'-Tetrachlorobiphenyl 
SW-846 Update V TWO - 36 Revision 5 

October 2012

TABLE 2-11 

METHOD 8085 (GC/AED) - PESTICIDES 

Abate (Temephos) Dichlorprop Metolachlor 

Acifluorfen Dichlorvos (DDVP) Metribuzin 

Alachlor Diclofol (Kelthane) Mevinphos 

Aldrin Diclofop-methyl MGK-264 

Ametryn Dieldrin Mirex 

Atraton Dimethoate Molinate 

Atrazine Dinoseb Napropamide 

Azinphos ethyl (Ethyl guthion) Dioxathion Norflurazon 

Azinphos methyl (Guthion) Diphenamid 4-Nitrophenol 

Benfluralin Disulfoton (Disyston) Oxyfluorfen 

α-BHC Diuron Parathion 

β-BHC Endosulfan I Pebulate 

δ-BHC Endosulfan II Pendimethalin 

γ-BHC (Lindane) Endosulfan sulfate Pentachlorophenol (PCP) 

Bromacil Endrin Phorate 

Bromoxynil (Brominal) Endrin aldehyde Phosphamidon 

Butachlor Endrin ketone Picloram 

Butylate EPN Profluralin 

Captafol Eptam (EPTC) Prometon (Pramitol 5p) 

Captan Ethalfluralin (Sonalan) Prometryn 

Carbophenothion Ethion Pronamide (Kerb) 

Carboxin Ethoprop Propachlor (Ramrod) 

trans-Chlordane Fenamiphos Propargite (S-181) 

Chlorpropham Fenarimol Propazine 

Chlorpyrifos Fenitrothion Propetamidophos 

Chlorthalonil (Daconil) Fensulfothion Ronnel 

Cyanazine Fluridone Simazine 
SW-846 Update V TWO - 37 Revision 5 

October 2012

TABLE 2-11 (continued) 

Cycloate Fonofos Sulfotepp 

2,4-D acid Gardona (Tetrachlovinphos) Sulprofos (Bolstar) 

Coumaphos Fenthion Silvex 

2,4-DB acid Heptachlor 2,4,5-T acid 

DCPA (Dacthal) Heptachlor epoxide 2,4,5-TB 

2,4'-DDD Hexachlorobenzene Tebuthiuron 

4,4'-DDD Hexachlorocyclopentadiene Terbacil 

2,4'-DDE Hexazinone Terbutryn (Igran) 

4,4'-DDE Imidan (Phosmet) 2,3,4,5-Tetrachlorophenol

2,4'-DDT Ioxynil 2,3,4,6-Tetrachlorophenol 

4,4'-DDT Malathion Triademefon 

DEF (Butifos) MCPA acid Triallate 

Demeton-O MCPP acid Triclopyr (Garlon) 

Demeton-S Merphos 2,4,5-Trichlorophenol 

Diallate Metalaxyl 2,4,6-Trichlorophenol 

Diazinon Methoxychlor Trifluralin (Treflan) 

Dicamba Methyl chlorpyrifos Vernolate 

Dichlobenil (Casoron) Methyl paraoxon 

3,5-Dichlorobenzoic acid Methyl parathion 
SW-846 Update V TWO - 38 Revision 5 

October 2012

TABLE 2-12 

METHOD 8091 (GC) - NITROAROMATICS AND CYCLIC KETONES 

Benefin 2,4-Dinitrotoluene 

Butralin 2,6-Dinitrotoluene 

1-Chloro-2,4-dinitrobenzene Isopropalin 

1-Chloro-3,4-dinitrobenzene 1,2-Naphthoquinone 

1-Chloro-2-nitrobenzene 1,4-Naphthoquinone 

1-Chloro-4-nitrobenzene Nitrobenzene 

2-Chloro-6-nitrotoluene 2-Nitrotoluene 

4-Chloro-2-nitrotoluene 3-Nitrotoluene 

4-Chloro-3-nitrotoluene 4-Nitrotoluene 

2,3-Dichloronitrobenzene Penoxalin [Pendimethalin] 

2,4-Dichloronitrobenzene Pentachloronitrobenzene 

3,5-Dichloronitrobenzene Profluralin 

3,4-Dichloronitrobenzene 2,3,4,5-Tetrachloronitrobenzene 

2,5-Dichloronitrobenzene 2,3,5,6-Tetrachloronitrobenzene 

Dinitramine 1,2,3-Trichloro-4-nitrobenzene 

1,2-Dinitrobenzene 1,2,4-Trichloro-5-nitrobenzene 

1,3-Dinitrobenzene 2,4,6-Trichloronitrobenzene 

1,4-Dinitrobenzene Trifluralin 

TABLE 2-13 

METHOD 8095 (GC) - EXPLOSIVES 

2-Amino-4,6-dinitrotoluene 2-Nitrotoluene 

4-Amino-2,6-dinitrotoluene 3-Nitrotoluene 

3,5-Dinitroaniline 4-Nitrotoluene 

1,3-Dinitrobenzene Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine 

2,4-Dinitrotoluene Pentaerythritoltetranitrate 

2,6-Dinitrotoluene 1,3,5-Trinitrobenzene 

Hexahydro-1,3,5-trinitro-1,3,5-triazine 2,4,6-Trinitrophenylmethylnitramine 

Nitrobenzene 2,4,6-Trinitrotoluene 

Nitroglycerine 
SW-846 Update V TWO - 39 Revision 5 

October 2012

TABLE 2-14 

METHOD 8100 - POLYNUCLEAR AROMATIC HYDROCARBONS 

Acenaphthene Dibenz(a,h)anthracene 

Acenaphthylene 7H-Dibenzo(c,g)carbazole 

Anthracene Dibenzo(a,e)pyrene 

Benz(a)anthracene Dibenzo(a,h)pyrene 

Benzo(b)fluoranthene Dibenzo(a,i)pyrene 

Benzo(j)fluoranthene Fluoranthene 

Benzo(k)fluoranthene Fluorene 

Benzo(g,h,i)perylene Indeno(1,2,3-cd)pyrene 

Benzo(a)pyrene 3-Methylcholanthrene 

Chrysene Naphthalene 

Dibenz(a,h)acridine Phenanthrene 

Dibenz(a,j)acridine Pyrene 

TABLE 2-15 

METHOD 8111 (GC) - HALOETHERS 

Bis(2-chloroethoxy)methane 2,5-Dichlorophenyl 4-nitrophenyl ether 

Bis(2-chloroethyl) ether 2,4-Dichlorophenyl 4-nitrophenyl ether 

Bis(2-chloro-1-methylethyl) ether 2,3-Dichlorophenyl 4-nitrophenyl ether 

4-Bromophenyl phenyl ether 3,4-Dichlorophenyl 4-nitrophenyl ether 

4-Chlorophenyl phenyl ether 4-Nitrophenyl phenyl ether 

2-Chlorophenyl 4-nitrophenyl ether 2,4,6-Trichlorophenyl 4-nitrophenyl ether 

3-Chlorophenyl 4-nitrophenyl ether 2,3,6-Trichlorophenyl 4-nitrophenyl ether 

4-Chlorophenyl 4-nitrophenyl ether 2,3,5-Trichlorophenyl 4-nitrophenyl ether 

2,4-Dibromophenyl 4-nitrophenyl ether 2,4,5-Trichlorophenyl 4-nitrophenyl ether 

2,4-Dichlorophenyl 3-methyl-4-nitrophenyl ether 3,4,5-Trichlorophenyl 4-nitrophenyl ether 

2,6-Dichlorophenyl 4-nitrophenyl ether 2,3,4-Trichlorophenyl 4-nitrophenyl ether 

3,5-Dichlorophenyl 4-nitrophenyl ether 
SW-846 Update V TWO - 40 Revision 5 

October 2012

TABLE 2-16 

METHOD 8121 (GC) - CHLORINATED HYDROCARBONS 

Benzal chloride δ-Hexachlorocyclohexane (δ-BHC) 

Benzotrichloride γ-Hexachlorocyclohexane (γ-BHC) 

Benzyl chloride Hexachlorocyclopentadiene 

2-Chloronaphthalene Hexachloroethane 

1,2-Dichlorobenzene Pentachlorobenzene 

1,3-Dichlorobenzene 1,2,3,4-Tetrachlorobenzene 

1,4-Dichlorobenzene 1,2,3,5-Tetrachlorobenzene 

Hexachlorobenzene 1,2,4,5-Tetrachlorobenzene 

Hexachlorobutadiene 1,2,3-Trichlorobenzene 

α-Hexachlorocyclohexane (α-BHC) 1,2,4-Trichlorobenzene 

β-Hexachlorocyclohexane (β-BHC) 1,3,5-Trichlorobenzene 

TABLE 2-17 

METHOD 8131 (GC) - ANILINE AND SELECTED DERIVATIVES

Aniline 2,6-Dibromo-4-nitroaniline 

4-Bromoaniline 3,4-Dichloroaniline 

2-Bromo-6-chloro-4-nitroanilne 2,6-Dichloro-4-nitroaniline 

2-Bromo-4,6-dintroaniline 2,4-Dinitroaniline 

2-Chloroaniline 2-Nitroaniline 

3-Chloroaniline 3-Nitroaniline 

4-Chloroaniline 4-Nitroaniline 

2-Chloro-4,6-dinitroaniline 2,4,6-Trichloroaniline 

2-Chloro-4-nitroaniline 2,4,5-Trichloroaniline 

4-Chloro-2-nitroaniline 
SW-846 Update V TWO - 41 Revision 5 

October 2012

TABLE 2-18 

METHOD 8141 (GC) - ORGANOPHOSPHORUS COMPOUNDS 

Aspon Disulfoton Parathion, methyl 

Atrazine EPN Pebulate 

Azinphos-ethyl EPTC o-Phenylenediamine 

Azinphos-methyl Ethion Phorate 

Bendiocarb Ethoprop Phosmet 

Bolstar (Sulprofos) Famphur Phosphamidon 

Butylate Fenitrothion Propham 

Carbophenothion Fensulfothion Prosulfocarb 

Chlorfenvinphos Fenthion Ronnel 

Chlorpyrifos Fonophos Simazine 

Chlorpyrifos methyl Hexamethyl phosphoramide 

(HMPA) 

Stirophos (Tetrachlorvinphos, 

Gardona) 

Coumaphos Leptophos Sulfotepp 

Crotoxyphos Malathion Tetraethyl pyrophosphate (TEPP) 

Demeton-O, and -S Merphos Terbufos 

Diazinon Methiocarb Triallate 

Dichlorofenthion Mevinphos Thionazin (Zinophos) 

Dichlorvos (DDVP) Molinate Tokuthion (Prothiofos) 

Dicrotophos Monocrotophos Trichlorfon 

Dimethoate Naled Trichloronate 

Dioxathion Parathion, ethyl Tri-o-cresyl phosphate (TOCP) 
SW-846 Update V TWO - 42 Revision 5 

October 2012

TABLE 2-19 

METHOD 8151 (GC USING METHYLATION OR PENTAFLUOROBENZYLATION 

DERIVATIZATION) - CHLORINATED HERBICIDES 

Acifluorfen Dicamba MCPP 

Bentazon 3,5-Dichlorobenzoic acid 4-Nitrophenol 

Chloramben Dichloroprop Pentachlorophenol 

2,4-D Dinoseb Picloram 

Dalapon 5-Hydroxydicamba 2,4,5-TP (Silvex) 

2,4-DB MCPA 2,4,5-T 

DCPA diacid 

TABLE 2-20 

METHOD 8260 (GC/MS) - VOLATILE ORGANIC COMPOUNDS 

Acetone Dibromofluoromethane Methylene chloride 

Acetonitrile Dibromomethane Methyl acrylate 

Acrolein (Propenal) 1,2-Dichlorobenzene Methyl methacrylate 

Acrylonitrile 1,3-Dichlorobenzene 4-Methyl-2-pentanone (MIBK) 

Allyl alcohol 1,4-Dichlorobenzene Naphthalene 

Allyl chloride cis-1,4-Dichloro-2-butene Nitrobenzene 

Benzene trans-1,4-Dichloro-2-

butene 

2-Nitropropane 

Benzyl chloride Dichlorodifluoromethane N-Nitroso-di-n-butylamine 

Bis(2-chloroethyl)-sulfide 1,1-Dichloroethane Paraldehyde 

Bromoacetone 1,2-Dichloroethane Pentachloroethane 

Bromobenzene 1,1-Dichloroethene Pentafluorobenzene 

Bromochloromethane cis-1,2-Dichloroethene 2-Pentanone 

Bromodichloromethane trans-1,2-Dichloroethene 2-Picoline 

Bromoform 1,2-Dichloropropane 1-Propanol 

Bromomethane 1,3-Dichloropropane 2-Propanol 
SW-846 Update V TWO - 43 Revision 5 

October 2012

TABLE 2-20 (continued) 

n-Butanol 2,2-Dichloropropane Propargyl alcohol 

2-Butanone (MEK) 1,3-Dichloro-2-propanol ß-Propiolactone 

t-Butyl alcohol 1,1-Dichloropropene Propionitrile (Ethyl cyanide) 

n-Butylbenzene cis-1,3-Dichloropropene n-Propylamine 

sec-Butylbenzene trans-1,3-Dichloropropene n-Propylbenzene 

tert-Butylbenzene 1,2,3,4-Diepoxybutane Pyridine 

Carbon disulfide Diethyl ether Styrene 

Carbon tetrachloride 1,4-Dioxane 1,1,1,2-Tetrachloroethane 

Chloral hydrate Epichlorohydrin 1,1,2,2-Tetrachloroethane 

Chloroacetonitrile Ethanol Tetrachloroethene 

Chlorobenzene Ethyl acetate Toluene 

1-Chlorobutane Ethylbenzene o-Toluidine 

Chlorodibromomethane Ethylene oxide 1,2,3-Trichlorobenzene 

Chloroethane Ethyl methacrylate 1,2,4-Trichlorobenzene 

2-Chloroethanol Hexachlorobutadiene 1,1,1-Trichloroethane 

2-Chloroethyl vinyl ether Hexachloroethane 1,1,2-Trichloroethane 

Chloroform 2-Hexanone Trichloroethene 

1-Chlorohexane 2-Hydroxypropionitrile Trichlorofluoromethane 

Chloromethane Iodomethane 1,2,3-Trichloropropane 

Chloroprene Isobutyl alcohol 1,2,4-Trimethylbenzene

3-Chloropropionitrile Isopropylbenzene 1,3,5-Trimethylbenzene 

2-Chlorotoluene p-Isopropyltoluene Vinyl acetate 

4-Chlorotoluene Malononitrile Vinyl chloride 

Crotonaldehyde Methacrylonitrile o-Xylene 

1,2-Dibromo-3-chloropropane Methanol m-Xylene 

1,2-Dibromoethane Methyl-t-butyl ether p-Xylene 

 
SW-846 Update V TWO - 44 Revision 5 

October 2012

TABLE 2-21 

METHOD 8261 (VD/GC/MS) - VOLATILE ORGANIC COMPOUNDS

Acetone 1,3-Dichlorobenzene Methacrylonitrile 

Acetonitrile 1,4-Dichlorobenzene Methyl t-butyl ether (MTBE) 

Acetophenone cis-1,4-Dichloro-2-butene Methylene chloride 

Acrolein trans-1,4-Dichloro-2-butene Methyl methacrylate 

Acrylonitrile Dichlorodifluoromethane 1-Methylnaphthalene 

Allyl Chloride 1,1-Dichloroethane 2-Methylnaphthalene 

t-Amyl ethyl ether (TAEE) 

(4,4-Dimethyl-3-oxahexane) 

1,2-Dichloroethane 4-Methyl-2-pentanone 

t-Amyl methyl ether (TAME) 1,1-Dichloroethene Naphthalene 

Aniline trans-1,2-Dichloroethene N-Nitrosodimethylamine 

Benzene cis-1,2-Dichloroethene N-Nitrosodi-n-propylamine 

Bromochloromethane 1,2-Dichloropropane N-Nitrosomethylethylamine 

Bromodichloromethane 1,3-Dichloropropane N-Nitrosodibutylamine 

Bromoform 2,2-Dichloropropane N-Nitrosodiethylamine 

Bromomethane 1,1-Dichloropropene Pentachloroethane 

2-Butanone cis-1,3-Dichloropropene 2-Picoline 

n-Butylbenzene trans-1,3-Dichloropropene Propionitrile 

sec-Butylbenzene Diethyl ether n-Propylbenzene 

tert-Butylbenzene Diisopropyl ether (DIPE) Pyridine 

Carbon disulfide 1,4-Dioxane Styrene 

Carbon tetrachloride Ethanol 1,1,2,2-Tetrachloroethane 

Chlorobenzene Ethyl acetate Tetrachloroethene 

Chlorodibromomethane Ethylbenzene Tetrahydrofuran 

Chloroethane Ethyl t-butyl ether (ETBE) Toluene 

Chloroform Ethyl methacrylate o-Toluidine 

Chloromethane Hexachlorobutadiene 1,2,3-Trichlorobenzene 

2-Chlorotoluene 2-Hexanone 1,2,4-Trichlorobenzene 

4-Chlorotoluene Iodomethane 1,1,1-Trichloroethane 

1,2-Dibromo-3-chloropropane Isobutyl alcohol 1,1,2-Trichloroethane 

Dibromomethane Isopropylbenzene Trichloroethene 

1,2-Dichlorobenzene p-Isopropyltoluene Trichlorofluoromethane 
SW-846 Update V TWO - 45 Revision 5 

October 2012

TABLE 2-21 (continued) 

1,2,3-Trichloropropane o-Xylene 

1,2,4-Trimethylbenzene m-Xylene 

1,3,5-Trimethylbenzene p-Xylene 

Vinyl chloride 

TABLE 2-22 

METHOD 8270 (GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene Endrin aldehyde 

Acenaphthylene Endrin ketone 

Acetophenone EPN 

2-Acetylaminofluorene Ethion 

1-Acetyl-2-thiourea Ethyl carbamate 

Aldrin Ethyl methanesulfonate 

2-Aminoanthraquinone Famphur 

Aminoazobenzene Fensulfothion 

4-Aminobiphenyl Fenthion 

3-Amino-9-ethylcarbazole Fluchloralin 

Anilazine Fluoranthene 

Aniline Fluorene 

o-Anisidine Heptachlor 

Anthracene Heptachlor epoxide 

Aramite Hexachlorobenzene 

Aroclor-1016 Hexachlorobutadiene 

Aroclor-1221 Hexachlorocyclopentadiene 

Aroclor-1232 Hexachloroethane 

Aroclor-1242 Hexachlorophene 

Aroclor-1248 Hexachloropropene 
SW-846 Update V TWO - 46 Revision 5 

October 2012

Table 2-22 (continued) 

Aroclor-1254 Hexamethylphosphoramide 

Aroclor-1260 Hydroquinone 

Azinphos-methyl Indeno(1,2,3-cd)pyrene 

Barban Isodrin 

Benz(a)anthracene Isophorone 

Benzidine Isosafrole 

Benzo(b)fluoranthene Kepone 

Benzo(k)fluoranthene Leptophos 

Benzoic acid Malathion 

Benzo(g,h,i)perylene Maleic anhydride 

Benzo(a)pyrene Mestranol 

p-Benzoquinone Methapyrilene 

Benzyl alcohol Methoxychlor 

α-BHC 3-Methylcholanthrene 

β-BHC 4,4'-Methylenebis(2-chloroaniline) 

δ-BHC 4,4'-Methylenebis(N,N-dimethylaniline) 

γ-BHC (Lindane) Methyl methanesulfonate 

Bis(2-chloroethoxy)-methane 2-Methylnaphthalene 

Bis(2-chloroethyl)ether Methyl parathion 

Bis(2-chloro-1-methylethyl)ether 2-Methylphenol 

Bis(2-ethylhexyl)phthalate 3-Methylphenol 

4-Bromophenyl phenyl ether 4-Methylphenol 

Bromoxynil Mevinphos 

Butyl benzyl phthalate Mexacarbate 

Captafol Mirex 

Captan Monocrotophos 

Carbaryl Naled 

Carbofuran Naphthalene 
SW-846 Update V TWO - 47 Revision 5 

October 2012

Table 2-22 (continued) 

Carbophenothion 1,4-Naphthoquinone 

Chlordane (NOS) 1-Naphthylamine 

Chlorfenvinphos 2-Naphthylamine 

4-Chloroaniline Nicotine 

Chlorobenzilate 5-Nitroacenaphthene 

5-Chloro-2-methylaniline 2-Nitroaniline 

4-Chloro-3-methylphenol 3-Nitroaniline 

3-(Chloromethyl)pyridine hydrochloride 4-Nitroaniline 

1-Chloronaphthalene 5-Nitro-o-anisidine 

2-Chloronaphthalene Nitrobenzene 

2-Chlorophenol 4-Nitrobiphenyl 

4-Chloro-1,2-phenylenediamine Nitrofen 

4-Chloro-1,3-phenylenediamine 2-Nitrophenol 

4-Chlorophenyl phenyl ether 4-Nitrophenol 

Chrysene Nitroquinoline-1-oxide 

Coumaphos N-Nitrosodi-n-butylamine 

p-Cresidine N-Nitrosodiethylamine 

Crotoxyphos N-Nitrosodimethylamine 

2-Cyclohexyl-4,6-dinitrophenol N-Nitrosodiphenylamine 

4,4'-DDD N-Nitrosodi-n-propylamine 

4,4'-DDE N-Nitrosomethylethylamine 

4,4'-DDT N-Nitrosomorpholine 

Demeton-O N-Nitrosopiperidine 

Demeton-S N-Nitrosopyrrolidine 

Diallate (cis or trans) 5-Nitro-o-toluidine 

2,4-Diaminotoluene Octamethyl pyrophosphoramide 

Dibenz(a,j)acridine 4,4'-Oxydianiline 

Dibenz(a,h)anthracene Parathion 
SW-846 Update V TWO - 48 Revision 5 

October 2012

Table 2-22 (continued) 

Dibenzofuran Pentachlorobenzene 

Dibenzo(a,e)pyrene Pentachloronitrobenzene 

1,2-Dibromo-3-chloropropane Pentachlorophenol 

Di-n-butyl phthalate Phenacetin 

Dichlone Phenanthrene 

1,2-Dichlorobenzene Phenobarbital 

1,3-Dichlorobenzene Phenol 

1,4-Dichlorobenzene 1,4-Phenylenediamine 

3,3'-Dichlorobenzidine Phorate 

2,4-Dichlorophenol Phosalone 

2,6-Dichlorophenol Phosmet 

Dichlorovos Phosphamidion 

Dicrotophos Phthalic anhydride 

Dieldrin 2-Picoline (2-Methylpyridine) 

Diethyl phthalate Piperonyl sulfoxide 

Diethylstilbestrol Pronamide 

Diethyl sulfate Propylthiouracil 

Dimethoate Pyrene 

3,3'-Dimethoxybenzidine Resorcinol 

Dimethylaminoazobenzene Safrole 

7,12-Dimethylbenz(a)anthracene Strychnine 

3,3'-Dimethylbenzidine Sulfallate 

α,α-Dimethylphenethylamine Terbufos 

2,4-Dimethylphenol 1,2,4,5-Tetrachlorobenzene 

Dimethyl phthalate 2,3,4,6-Tetrachlorophenol 

1,2-Dinitrobenzene Tetrachlorvinphos 

1,3-Dinitrobenzene Tetraethyl dithiopyrophosphate 

1,4-Dinitrobenzene Tetraethyl pyrophosphate 
SW-846 Update V TWO - 49 Revision 5 

October 2012

Table 2-22 (continued) 

4,6-Dinitro-2-methylphenol Thionazine 

2,4-Dinitrophenol Thiophenol (Benzenethiol) 

2,4-Dinitrotoluene Toluene diisocyanate 

2,6-Dinitrotoluene o-Toluidine 

Dinocap Toxaphene 

Di-n-octyl phthalate 1,2,4-Trichlorobenzene 

Diphenylamine 2,4,5-Trichlorophenol 

5,5-Diphenylhydantoin 2,4,6-Trichlorophenol 

1,2-Diphenylhydrazine O,O,O-Triethylphosphorothioate 

Dinoseb Trifluralin 

Disulfoton 2,4,5-Trimethylaniline 

Endosulfan I Trimethyl phosphate 

Endosulfan II 1,3,5-Trinitrobenzene 

Endosulfan sulfate Tris(2,3-dibromopropyl)phosphate

Endrin Tri-p-tolyl phosphate 

 
SW-846 Update V TWO - 50 Revision 5 

October 2012

TABLE 2-23 

METHOD 8275 (TE/GC/MS) - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene 1,2,4-Trichlorobenzene 

Acenaphthylene 2-Chlorobiphenyl 

Anthracene 3,3'-Dichlorobiphenyl 

Benz(a)anthracene 2,2',5-Trichlorobiphenyl 

Benzo(a)pyrene 2,3',5-Trichlorobiphenyl 

Benzo(b)fluoranthene 2,4',5-Trichlorobiphenyl 

Benzo(g,h,i)perylene 2,2',5,5'-Tetrachlorobiphenyl 

Benzo(k)fluoranthene 2,2'4,5'-Tetrachlorobiphenyl 

4-Bromophenyl phenyl ether 2,2'3,5'-Tetrachlorobiphenyl 

1-Chloronaphthalene 2,3',4,4'-Tetrachlorobiphenyl 

Chrysene 2,2',4,5,5'-Pentachlorobiphenyl 

Dibenzofuran 2,3',4,4',5-Pentachlorobiphenyl 

Dibenz(a,h)anthracene 2,2',3,4,4',5'- Hexachlorobiphenyl 

Dibenzothiophene 2,2',3,3',4,4'- Hexachlorobiphenyl

Fluoranthene 2,2',3,4',5,5',6- Heptachlorobiphenyl 

Fluorene 2,2',3,4,4',5,5'- Heptachlorobiphenyl 

Hexachlorobenzene 2,2',3,3',4,4',5- Heptachlorobiphenyl 

Indeno(1,2,3-cd)pyrene 2,2',3,3',4,4',5,5'- Octachlorobiphenyl 

Naphthalene 2,2',3,3'4,4',5,5',6- Nonachlorobiphenyl 

Phenanthrene 2,2',3,3'4,4',5,5',6,6'- Decachlorobiphenyl 

Pyrene 
SW-846 Update V TWO - 51 Revision 5 

October 2012

TABLE 2-24 

METHODS 8280 (HRGC/LRMS) AND 8290 (HRGC/HRMS) - POLYCHLORINATED DIBENZOp-DIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS (PCDFs) 

2,3,7,8-TCDD 1,2,3,7,8-PeCDF 

TCDD, total 2,3,4,7,8-PeCDF 

1,2,3,7,8-PeCDD PeCDF, total 

PeCDD, total 1,2,3,4,7,8-HxCDF 

1,2,3,4,7,8-HxCDD 1,2,3,6,7,8-HxCDF 

1,2,3,6,7,8-HxCDD 1,2,3,7,8,9-HxCDF 

1,2,3,7,8,9-HxCDD 2,3,4,6,7,8-HxCDF 

HxCDD, total HxCDF, total 

1,2,3,4,6,7,8-HpCDD 1,2,3,4,6,7,8-HpCDF 

HpCDD, total 1,2,3,4,7,8,9-HpCDF 

OCDD HpCDF, total 

2,3,7,8-TCDF OCDF 

TCDF, total 

TABLE 2-25 

METHOD 8310 (HPLC) - POLYNUCLEAR AROMATIC HYDROCARBONS 

Acenaphthene Chrysene 

Acenaphthylene Dibenzo(a,h)anthracene 

Anthracene Fluoranthene 

Benz(a)anthracene Fluorene 

Benzo(a)pyrene Indeno(1,2,3-cd)pyrene 

Benzo(b)fluoranthene Naphthalene 

Benzo(g,h,i)perylene Phenanthrene 

Benzo(k)fluoranthene Pyrene 
SW-846 Update V TWO - 52 Revision 5 

October 2012

TABLE 2-26 

METHOD 8315 - CARBONYL COMPOUNDS 

Acetaldehyde Decanal Octanal 

Acetone 2,5-Dimethylbenzaldehyde Pentanal (Valeraldehyde) 

Acrolein Formaldehyde Propanal (Propionaldehyde) 

Benzaldehyde Heptanal m-Tolualdehyde 

Butanal (Butyraldehyde) Hexanal (Hexaldehyde) o-Tolualdehyde 

Crotonaldehyde Isovaleraldehyde p-Tolualdehyde 

Cyclohexanone Nonanal 

TABLE 2-27 

METHOD 8316 (HPLC) 

Acrylamide 

Acrylonitrile 

Acrolein 

TABLE 2-28 

METHOD 8318 (HPLC) - N-METHYLCARBAMATES 

Aldicarb (Temik) Dioxacarb Mexacarbate 

Aldicarb sulfone Formetanate hydrochloride Oxamyl 

Bendiocarb 3-Hydroxycarbofuran Promecarb 

Carbaryl (Sevin) Methiocarb (Mesurol) Propoxur (Baygon) 

Carbofuran (Furadan) Methomyl (Lannate) Thiodicarb 

m-Cumenyl methylcarbamate Metolcarb 
SW-846 Update V TWO - 53 Revision 5 

October 2012

TABLE 2-29 

METHOD 8321 (HPLC/TS/MS) - NONVOLATILE ORGANIC COMPOUNDS 

Azo Dyes Carbamates

Disperse Red 1 Aldicarb 

Disperse Red 5 Aldicarb sulfone 

Disperse Red 13 Aldicarb sulfoxide 

Disperse Yellow 5 Aminocarb 

Disperse Orange 3 Barban 

Disperse Orange 30 Benomyl 

Disperse Brown 1 Bendiocarb 

Solvent Red 3 Bromacil 

Solvent Red 23 Butylate 

Carbaryl 

Carbendazim 

Chlorinated Phenoxyacid Compounds Carbofuran 

2,4-D Carbofuran phenol 

2,4-D, butoxyethanol ester Carbosulfan 

2,4-D, ethylhexyl ester Chloropropham 

2,4-DB Chloroxuron 

Dalapon m-Cumenyl methyl carbamate 

Dicamba Diuron 

Dichlorprop EPTC 

Dinoseb Fenuron 

MCPA Fluometuron 

MCPP Formetanate hydrochloride 

Silvex (2,4,5-TP) 3-Hydroxycarbofuran 

2,4,5-T Linuron 

2,4,5-T, butyl ester Methiocarb 

2,4,5-T, butoxyethanol ester Methomyl 
SW-846 Update V TWO - 54 Revision 5 

October 2012

Table 2-29 (continued) 

Organophosphorus Compounds Carbamates (cont.)

Asulam Metolcarb 

Fensulfothion Mexacarbate 

Dichlorvos (DDVP) Molinate 

Dimethoate Monuron 

Disulfoton Neburon 

Parathion methyl Oxamyl 

Merphos Pebulate 

Methomyl o-Phenylenediamine 

Monocrotophos Physostigmine 

Famphur Physostigmine salicylate 

Naled Promecarb 

Phorate Propham 

Trichlorfon Propoxur 

Thiofanox Prosulfocarb 

Tris(2,3-dibromopropyl) phosphate (Tris-BP) Siduron

Tebuthiuron 

Anthraquinone Dyes Thiodicarb 

Disperse Blue 3 Thiophanate-methyl 

Disperse Blue 14 Triallate 

Disperse Red 60 

 
SW-846 Update V TWO - 55 Revision 5 

October 2012

TABLE 2-30 

METHOD 8325 (HPLC/PB/MS) - NONVOLATILE ORGANIC COMPOUNDS 

Benzidine 3,3'-Dimethylbenzidine 

Benzoylprop ethyl Diuron 

Carbaryl Linuron (Lorox) 

o-Chlorophenyl thiourea Monuron 

3,3'-Dichlorobenzidine Rotenone 

3,3'-Dimethoxybenzidine Siduron 

TABLE 2-31 

METHOD 8330 (HPLC) - NITROAROMATICS AND NITRAMINES 

4-Amino-2,6-dinitrotoluene (4-Am-DNT) Nitrobenzene (NB) 

2-Amino-4,6-dinitrotoluene (2-Am-DNT) 2-Nitrotoluene (2-NT) 

1,3-Dinitrobenzene (1,3-DNB) 3-Nitrotoluene (3-NT) 

2,4-Dinitrotoluene (2,4-DNT) 4-Nitrotoluene (4-NT) 

2,6-Dinitrotoluene (2,6-DNT) Octahydro-1,3,5,7-tetranitro-1,3,5,7- 

tetrazocine (HMX) 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 1,3,5-Trinitrobenzene (1,3,5-TNB) 

Methyl-2,4,6-trinitrophenyl-nitramine (Tetryl) 2,4,6-Trinitrotoluene (2,4,6-TNT) 

TABLE 2-32 

METHOD 8331 (HPLC) 

Tetrazene 
SW-846 Update V TWO - 56 Revision 5 

October 2012

TABLE 2-33 

METHOD 8332 (HPLC) 

Nitroglycerine 

TABLE 2-34 

METHOD 8410 - SEMIVOLATILE ORGANIC COMPOUNDS 

Acenaphthene 2,6-Dinitrotoluene 

Acenaphthylene Di-n-octyl phthalate 

Anthracene Di-n-propyl phthalate 

Benzo(a)anthracene Fluoranthene 

Benzo(a)pyrene Fluorene 

Benzoic acid Hexachlorobenzene 

Bis(2-chloroethoxy)methane 1,3-Hexachlorobutadiene 

Bis(2-chloroethyl)ether Hexachlorocyclopentadiene 

Bis(2-chloro-1-methylethyl)ether Hexachloroethane 

Bis(2-ethylhexyl) phthalate Isophorone 

4-Bromophenyl phenyl ether 2-Methylnaphthalene 

Butyl benzyl phthalate 2-Methylphenol 

4-Chloroaniline 4-Methylphenol 

4-Chloro-3-methylphenol Naphthalene 

2-Chloronaphthalene 2-Nitroaniline 

2-Chlorophenol 3-Nitroaniline 

4-Chlorophenol 4-Nitroaniline 

4-Chlorophenyl phenyl ether Nitrobenzene 

Chrysene 2-Nitrophenol 

Dibenzofuran 4-Nitrophenol 

Di-n-butyl phthalate N-Nitrosodimethylamine 

1,2-Dichlorobenzene N-Nitrosodiphenylamine 

1,3-Dichlorobenzene N-Nitroso-di-n-propylamine 

1,4-Dichlorobenzene Pentachlorophenol 

2,4-Dichlorophenol Phenanthrene 

Diethyl phthalate Phenol 
SW-846 Update V TWO - 57 Revision 5 

October 2012

Table 2-34 (continued) 

Dimethyl phthalate Pyrene 

4,6-Dinitro-2-methylphenol 1,2,4-Trichlorobenzene 

2,4-Dinitrophenol 2,4,5-Trichlorophenol 

2,4-Dinitrotoluene 2,4,6-Trichlorophenol 

TABLE 2-35 

METHOD 8430 (GC/FT-IR) - BIS(2-CHLOROETHYL) ETHER AND ITS HYDROLYSIS 

PRODUCTS 

Bis(2-chloroethyl) ether 

2-Chloroethanol 

2-(2-Chloroethoxy)ethanol 

Diethylene glycol 

Ethylene glycol 

TABLE 2-36 

METHOD 8510 (COLORIMETRIC SCREENING) - RDX AND HMX 

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 

Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) 

TABLE 2-37 

METHOD 8535 (COLORIMETRIC SCREENING) - VOLATILE ORGANIC HALIDES 

Trichloroethylene 

Perchloroethylene (Tetrachloroethene) 

Carbon tetrachloride 

Trihalomethanes 
SW-846 Update V TWO - 58 Revision 5 

October 2012

TABLE 2-38 

METHOD 8540 (UV-INDUCED COLORIMETRY) - PENTACHLOROPHENOL 

Pentachlorophenol 

TABLE 2-39 

DETERMINATIVE METHODS FOR INORGANIC ANALYTES 

Analyte Applicable Methods 

Aluminum ............................................................................................... 6010, 6020, 7000, 7010 

Antimony .............................................................................. 6010, 6020, 6200, 6800, 7000, 7062 

Arsenic ....................................................................... 6010, 6020, 6200, 7010, 7061, 7062, 7063 

Barium ................................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Beryllium ................................................................................................. 6010, 6020, 7000, 7010 

Boron .......................................................................................................................... 6010, 6800 

Bromide ............................................................................................................ 6500, 9056, 9211 

Cadmium ............................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Calcium ..........................................................................................6010, 6020, 6200, 6800, 7000 

Chloride ..................................................................... 6500, 9056, 9057, 9212, 9250, 9251, 9253 

Chromium ............................................................................ 6010, 6020, 6200, 6800, 7000, 7010 

Chromium, hexavalent ......................................................... 6800, 7195, 7196, 7197, 7198, 7199 

Cobalt ............................................................................................6010, 6020, 6200, 7000, 7010 

Copper ................................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Cyanide...................................................................... 9010, 9012, 9013, 9014, 9015, 9016, 9213 

Fluoride ............................................................................................................. 6500, 9056, 9214 

Iron ...................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Lead ..................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Lithium ........................................................................................................................ 6010, 7000 

Magnesium ............................................................................................. 6010, 6020, 6800, 7000 

Manganese ....................................................................................6010, 6020, 6200, 7000, 7010 

Mercury ................................................. 6010, 6020, 6200, 6800, 7470, 7471, 7472, 7473, 7474 

Molybdenum ..................................................................................6010, 6200, 6800, 7000, 7010 

Nickel ................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Nitrate ............................................................................................................... 6500, 9056, 9210 

Nitrite ................................................................................................................ 6500, 9056, 9216 

Osmium ................................................................................................................................ 7000 

Perchlorate ................................................................................................................. 6850, 6860

Phosphate ................................................................................................................... 6500, 9056 

Phosphorus ........................................................................................................................... 6010 

Phosphorus, white ................................................................................................................ 7580 

Potassium ......................................................................................6010, 6020, 6200, 6800, 7000 

Rubidium ............................................................................................................................... 6200 

Selenium .................................................................... 6010, 6020, 6200, 6800, 7010, 7741, 7742 

Silver .................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Silica ..................................................................................................................................... 6010 
SW-846 Update V TWO - 59 Revision 5 

October 2012

Table 2-39 (continued) 

 

Sodium ............................................................................................................. 6010, 6020, 7000 

Strontium ................................................................................................ 6010, 6200, 6800, 7000 

Sulfate ...........................................................................................6500, 9035, 9036, 9038, 9056 

Sulfide ............................................................................................................... 9030, 9031, 9215 

Thallium ............................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Thorium................................................................................................................................. 6200 

Tin ..................................................................................................................... 6010, 6200, 7000 

Titanium ...................................................................................................................... 6010, 6200 

Vanadium ............................................................................. 6010, 6020, 6200, 6800, 7000, 7010 

Zinc ...................................................................................... 6010, 6020, 6200, 6800, 7000, 7010 

Zirconium .............................................................................................................................. 6200 
 SW-846 Update V TWO - 60 Revision 5 

 October 2012

TABLE 2-40(A) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANIC CHEMICALSa

(Note: Footnotes are located on the last page of the table.) 

VOLATILE ORGANICS

Sample Matrix Container Preservative1 Holding Time1Concentrated waste samples 

Method 5035: See the method. Method 5021: See the method. Methods 5031 and 5032: See the methods. Use PTFE-lined lids for all procedures. 

Cool to ≤6 °C. 14 days 

Aqueous samples with no 

residual chlorine present 

Methods 5030, 5031, and 5032: 2 x 40-mL vials with PTFE-lined septum caps 

Cool to ≤6 °C and adjust pH to less than 2 with 

H2SO4, HCl, or solid NaHSO4

If carbonaceous materials are present, or if MTBE and other fuel oxygenate ethers are 

present and a high temperature sample preparative method is to be used, do not acid preserve the samples. 

If the reactive compound 2-chloroethyl vinyl etherb is an analyte of interest, collect a 

second set of samples without acid 

preservatives and analyze immediately. 

14 days 

7 days 7 days
TABLE 2-40(A) (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANIC CHEMICALSa 

 SW-846 Update V TWO - 61 Revision 5 

 October 2012

VOLATILE ORGANICS (continued)

Sample Matrix Container Preservative1 Holding Time1

Aqueous samples WITH 

residual chlorine present 

Methods 5030, 5031, and 5032: 2 x 40-mL vials with PTFE-lined septum caps 

Collect sample in a 125-mL container which has been pre-preserved with 4 drops of 10% sodium thiosulfate solution. Gently swirl to mix sample and transfer to a 40-mL VOA vial. Cool to ≤6 °C and adjust pH to less than 2 with 

H2SO4, HCl, or solid NaHSO4. If carbonaceous materials are present, or if 

MTBE and other fuel oxygenate ethers are 

present and a high temperature sample preparative method is to be used, do not acid preserve the samples. 

If the reactive compound 2-chloroethyl vinyl etherb is an analyte of interest, collect a 

second set of samples without acid 

preservatives and analyze immediately.

14 days 

7 days

 7 days

Acrolein and acrylonitrile 

in aqueous samples 

Methods 5030, 5031, and 5032: 2 x 40-mL vials with PTFE-lined septum caps 

Adjust to pH 4-5. Cool to ≤6 °C. 

These compounds are highly reactive and should be analyzed as soon as possible.

7 days 

Solid samples (e.g. soils, sediments, sludges, ash) 

Method 5035: See the method. Method 5021: See the method. Methods 5031 and 5032: See the methods. 

See the individual methods. If vinyl chloride, styrene, or 2-chloroethyl vinyl ether are analytes of interest, collect a second set of samples without acid preservatives and analyze as soon as possible.

 14 days 

7 days 
TABLE 2-40(A) (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANIC CHEMICALSa 

 SW-846 Update V TWO - 62 Revision 5 

 October 2012

SEMIVOLATILE ORGANICS/ORGANOCHLORINE PESTICIDES AND HERBICIDES 

Sample Matrix Container Preservative1 Holding Time1Concentrated waste samples 

125-mL wide-mouth glass with PTFE-lined lid 

None Samples extracted 

within 14 days and extracts analyzed within 40 days following extraction. 

Aqueous samples with no 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Cool to ≤6 °C. Samples extracted 

within 7 days and extracts analyzed within 40 days following extraction. 

Aqueous samples WITH 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Add 3-mL 10% sodium thiosulfate solution per 

gallon (or 0.008%). Addition of sodium thiosulfate solution to sample container may be performed in the laboratory prior to field use. Cool to ≤6 °C. 

Samples extracted within 7 days and extracts analyzed within 40 days following extraction. 

Solid samples (e.g. soils, sediments, sludges, ash) 

250-mL wide-mouth glass container with PTFE-lined lid 

Cool to ≤6 °C. Samples extracted 

within 14 days and extracts analyzed within 40 days following extraction. 
TABLE 2-40(A) (continued) 

RECOMMENDED SAMPLE CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR ORGANIC CHEMICALSa 

 SW-846 Update V TWO - 63 Revision 5 

 October 2012

a The information presented in this table does not represent EPA requirements, but rather it is intended solely as guidance. Selection of containers, 

preservation techniques and applicable holding times should be based on the stated project-specific data quality objectives.

1 The exact sample, extract, and standard storage temperature should be based on project-specific requirements and/or manufacturer's 

recommendations for commercially available standards. Furthermore, alternative storage temperatures may be appropriate based on demonstrated analyte stability in a given matrix, provided the stated data quality objectives for a project-specific application are still attainable. 

2 A longer holding time may be appropriate if it can be demonstrated that the reported analyte concentrations are not adversely affected from 

preservation, storage and analyses performed outside the recommended holding times. 

POLYCHLORINATED BIPHENYLS, POLYCHLORINATED DIBENZO-p-DIOXINS, AND POLYCHLORINATED DIBENZOFURANS 

Sample Matrix Container Preservative1 Holding Time2Concentrated waste samples 

125-mL wide-mouth glass with PTFE-lined lid 

None None 

Aqueous samples with no 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Cool to ≤6 °C. None 

Aqueous samples WITH 

residual chlorine present 

4 x 1-L amber glass container with PTFElined lid, or other size, as appropriate, to allow use of entire sample for analysis. 

Add 3-mL 10% sodium thiosulfate solution per 

gallon (or 0.008%). Addition of sodium thiosulfate solution to sample container may be performed in the laboratory prior to field use. Cool to ≤6 °C 

None 

Solid samples (e.g. soils, sediments, sludges, ash) 

250-mL wide-mouth glass container with PTFE-lined lid. 

Cool to ≤6 °C. None 
SW-846 Update V TWO - 64 Revision 5 

 October 2012 

TABLE 2-40(B) 

RECOMMENDED CONTAINERS, PRESERVATION TECHNIQUES, AND HOLDING TIMES FOR INORGANIC AND 

OTHER ANALYTES IN AQUEOUS MATRICES 

(SEE CHAPTER THREE FOR MORE DETAILED GUIDANCE, INCLUDING REGARDING SOLID MATRICES) 

(Footnotes are located on the next page.) 

Name Container1 Preservation2 Holding Time3Inorganic Tests: Chloride P, G None required 28 days Cyanide, total and amenable to chlorination 

P, G Cool to ≤6 ̊C; if oxidizing agents present add 5 mL 0.1N NaAsO2

per L or 0.06 g of ascorbic acid per L; adjust pH>12 with 50% NaOH. See Method 9010 for other interferences. 

14 days 

Hydrogen ion (pH) P, G None required As soon as possible Nitrate P, G Cool to ≤6 ̊C. 48 hours Sulfate P, G Cool to ≤6 ̊C. 28 days Sulfide P, G Cool to ≤6 ̊C , add zinc acetate, NaOH to pH >9 7 days Metals: Chromium VI P, G Cool to ≤6 ̊C. 24 hours 

Mercury P, G HNO3 to pH<2 28 days 

Mercury (soil/sediment) P, G Cool to ≤6 ̊C. 28 days Mercury Species in soil/sediment P, G Cool to ≤6 ̊C. 5 days 

All Other Metals P, G HNO3 to pH<2 6 months 

Hexane Extractable Material (HEM; Oil and grease) 

G Cool to ≤6 ̊C,HCl or H2SO4 to pH<2 28 days 

Organic carbon, total (TOC) P, G Cool to ≤6 ̊C, store in dark; HCl or H2SO4 to pH<2 28 days Radiological Tests: 
SW-846 Update V TWO - 65 Revision 5 

 October 2012 

Name Container1 Preservation2 Holding Time3

Alpha, beta and radium P, G HNO3 to pH<2 6 months 

a The information presented in this table does not represent EPA requirements, but rather it is intended solely as guidance. Selection of 

containers, preservation techniques and applicable holding times should be based on the stated project-specific data quality objectives. 

See Chapter Three, Chapter Four, or the individual methods for more information. 1 Polyethylene (P) or glass (G) 2 The exact sample, extract, and standard storage temperature should be based on project-specific requirements and/or manufacturer's 

recommendations for commercially available standards. Furthermore, alternative storage temperatures may be appropriate based on demonstrated analyte stability in a given matrix, provided the stated data quality objectives for a project-specific application are still 

attainable. 

3 A longer holding time may be appropriate if it can be demonstrated that the reported analyte concentrations are not adversely affected 

by preservation, storage and analyses performed outside the recommended holding times. 
SW-846 Update V TWO - 66 Revision 5 

 October 2012 

TABLE 2-41 

PREPARATION METHODS FOR ORGANIC ANALYTES 

(Note: Footnotes are located on the last page of the table.) 

 Matrix 

Analyte Type Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 

Acid Extractable 3510 

3520 

(pH ≤ 2) 

3540 

3541 

354213

3545 

3546 

3550 

3520 

(pH ≤ 2) 

3650 

35803

Acrolein12, Acrylonitrile12, and 

Acetonitrile 

5031 

503212

5031 

503212

5031 

503212

3585 

Acrylamide 80324 

Aniline and Selected 

Derivatives 

3510 

3520 

(pH >11) 

503111

3540 

3541 

3545 

3550 

3520 

(pH >11) 

35803

Aromatic Volatiles 5021 

5030 

5032 

5021 

5032 

5035 

5030 

5032 

3585 

Base/Neutral Extractable 3510 

3520 

(pH >11) 

3540 

3541 

354213

3545 

3546 

3550 

3520 

(pH >11) 

3650 

35803

Carbamates 83185

8321 

83185

8321 

83185 83185

 

Chlorinated Herbicides 3535 

(pH < 1) 

81516

(pH ≤ 2) 

8321 

3545 

3546 

81516

8321 

81516

(pH ≤ 2) 

35803

Chlorinated Hydrocarbons 3510 

3520 

(pH as 

received) 

3540 

3541 

3550 

3520 

(pH as 

received) 

35803

Dyes 3510 

3520 

3540 

3541 

3545 

3550 

 
SW-846 Update V TWO - 67 Revision 5 

 October 2012 

TABLE 2-41 (continued) 

PREPARATION METHODS FOR ORGANIC ANALYTES 

Matrix 

Analyte Type Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 

Explosives 3535 

83307

83318

83307

83318

 

Formaldehyde 83159 83159 

Haloethers 3510 

3520 

3540 

3541 

3545 

3550 

Halogenated Volatiles 5021 

5030 

5032 

5021 

5032 

5035 

5030 5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 

Nitroaromatics 

and Cyclic Ketones 

3510 

3520 

(pH 5-9) 

3535 

3540 

3541 

3545 

3550 

3520 

(pH 5-9) 

35803

Nitrosamines 3510 

3520 

3540 

3541 

3545 

3550 

 

Non-halogenated Volatiles 5021 

5030 

5031 

5032 

5021 

5031 

5032 

5035 

5021 

5031 

5032 

5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 

Organochlorine Pesticides 3510 

3520 

3535 

(pH 5-9) 

3540 

3541 

3545 

3546 

3550 

3562 

3520 

(pH 5-9) 

35803

Organophosphorus 

Pesticides 

3510 

3520 

(pH 5-8) 

3535 

3540 

3541 

3545 

3546 

3520 

(pH 5-8) 

35803
SW-846 Update V TWO - 68 Revision 5 

 October 2012 

1

 The pH at which extraction should be performed is shown in parentheses. 

2

 If attempts to break an emulsion are unsuccessful, these methods may be used. 

3

 Method 3580 is only appropriate if the sample is soluble in the specified solvent. 

4

 Method 8032 contains the extraction, cleanup, and determinative procedures for this analyte. 

5

 Method 8318 contains the extraction, cleanup, and determinative procedures for these analytes. 

6

 Method 8151 contains the extraction, cleanup, and determinative procedures for these analytes. 

7

 Method 8330 contains the extraction, cleanup, and determinative procedures for these analytes. 

TABLE 2-41 (continued) 

PREPARATION METHODS FOR ORGANIC ANALYTES 

Matrix 

 Aqueous1 Solids 

Sludges and 

Emulsions1,2

Organic 

Liquids, 

Tars, Oils 3650 

35803

Phenols 3510 

3520 

(pH ≤ 2) 

3535 

3540 

3541 

3545 

3546 

3550 

3562 

3520 

(pH ≤ 2) 

3650 

35803

Phthalate Esters 3510 

3520 

3535 

(pH 5-7) 

3540 

3541 

3545 

3546 

3550 

3520 

(pH 5- 7) 

35803

Polychlorinated Biphenyls 3510 

3520 

3535 

(pH 5-9) 

3540 

3541 

3545 

3546 

3562 

3520 

(pH 5-9) 

35803

PCDDs and PCDFs 828010

829010

3545 

3546 

828010

829010

828010

829010

828010

829010

Polynuclear Aromatic 

Hydrocarbons 

3510 

3511 

3520 

(pH as 

received) 

3540 

3541 

3545 

3546 

3550 

3561 

3520 

(pH as 

received) 

35803

Volatile Organics 5021 

5030 

5031 

5032 

5021 

5031 

5032 

5035 

5021 

5030 

5031 

5032 

5021 

(methanol extr) 

5035 / 5030 

(methanol extr) 

5032 

3585 
SW-846 Update V TWO - 69 Revision 5 

 October 2012 

8

 Method 8331 is for Tetrazene only, and contains the extraction, cleanup, and determinative 

procedures for this analyte. 

9

 Method 8315 contains the extraction, cleanup, and determinative procedures for this analyte. 

10 Methods 8280 and 8290 contain the extraction, cleanup, and determinative procedures for these 

analytes. 

11 Method 5031 may be used when only aniline is to be determined. 

12 Method 5032 may be used for acrolein and acrylonitrile. 

13 Method 3542 is used for extraction of semivolatiles from stack samples collected using Method 

0010. 
SW-846 Update V TWO - 70 Revision 5 

 October 2012 

 TABLE 2-42 

 CLEANUP METHODS FOR ORGANIC ANALYTE EXTRACTS 

Analyte Type Method 

Acid Extractable 3650, 3640 

Base/Neutral Extractable 3650, 3640 

Carbamates 83181

Chlorinated Herbicides 81512

Chlorinated Hydrocarbons 3620, 3640 

Haloethers 3620, 3640 

Nitroaromatics & Cyclic Ketones 3620, 3640 

Nitrosamines 3610, 3620, 3640 

Organochlorine Pesticides 3620, 3630, 3640 

3660 

Organophosphorus Pesticides 3620 

Phenols 3630, 3640, 3650 

80413

Phthalate Esters 3610, 3611, 3620 

3640 

Polychlorinated Biphenyls 3620, 3630, 3640 

3660, 3665 

Polychlorinated Dibenzo-p-Dioxins and Polychlorinated Dibenzofurans 82804

82904

Polynuclear Aromatic Hydrocarbons 3610, 3611 

3630, 3640, 

3650 

1

 Method 8318 contains the extraction, cleanup, and determinative procedures for these analytes. 

2

 Method 8151 contains the extraction, cleanup, and determinative procedures for these analytes. 

3

 Method 8041 includes a derivatization technique followed by GC/ECD analysis, if interferences are encountered using GC/FID. 

4

 Methods 8280 and 8290 contain the extraction, cleanup, and determinative procedures for these analytes. 
SW-846 Update V TWO - 71 Revision 5 

 October 2012 

TABLE 2-43 

 DETERMINATIVE METHODS ORGANIC ANALYTES 

Analyte Type 

GC/MS 

Method 

Specific GC 

Method6

HPLC 

Method 

Acid Extractable 8270 84106 

Acrolein, Acrylonitrile, Acetonitrile 8260, 8261 8015, 8031, 

80331

 83152, 8316 

Acrylamide 8260 8032 8316 

Aniline and Selected Derivatives 8270 8131 

Aromatic Volatiles 8260, 8261 8021 

Base/Neutral Extractable 8270 84106

 83254

Carbamates 8318, 8321 

Chlorinated Herbicides 82703 8151 8321 

Chlorinated Hydrocarbons 8270 8121 

Diesel Range Organics (DRO) 8015, 84407

 

Dyes 8321 

Explosives 8095 8330, 8331, 8332 

Formaldehyde 8315 

Gasoline Range Organics (GRO) 8015 

Haloethers 8270 8111 

Halogenated Volatiles 8260, 8261 8011, 8021 

Nitroaromatics and Cyclic Ketones 8270 8091 83305

Nitrosoamines 8270 8070 

Non-halogenated Volatiles 8260 8015 8315 

Organochlorine Pesticides 82703 8081, 80856 

Organophosphorus Pesticides 82703 8141, 80856 8321 

Phenols 8270 8041, 84106 

Phthalate Esters 8270 8061, 84106 

Polychlorinated Biphenyls 82703 8082 

PCDDs and PCDFs 8280, 8290 

Polynuclear Aromatic Hydrocarbons 8270 8100, 84106

 8310 

Volatile Organics 8260, 8261 8011, 8015, 

8021, 8031, 

8032, 8033 

8315, 8316 

1

 Of these analytes, Method 8033 is for acetonitrile only. 

2

 Of these analytes, Method 8315 is for acrolein only. 

3

 This method is an alternative confirmation method, not the method of choice. 

4

 Benzidines and related compounds. 

5

 Nitroaromatics (see "Explosives"). 

6

 Includes GC/ES methods, e.g., Methods 8085 and 8410. 

7

 FT-IR determinative method only. Does not use GC.
SW-846 Update V TWO - 72 Revision 5 

 October 2012 

TABLE 2-44 

 PREPARATION METHODS FOR INORGANIC ANALYSES 1

Matrix Method 

Surface water 3005, 3010, 3015, 3020 

Groundwater 3005, 3010, 3015, 3020 

Extracts 3010, 3015, 3020 

Aqueous samples containing suspended solids 3010, 3015, 3020 

Oils 3031, 3040, 3051, 30522

Oil sludges 3031, 30522

Tars 3031, 30522

Waxes 3031, 3040, 30522

Paints 3031, 30522

Paint sludges 3031, 30522

Petroleum products 3031, 3040, 30522

Sediments 3050, 3051, 30522, 30603, 32004

Sludges 3050, 3051, 30522

, 30603

Soil samples 3050, 3051, 30522, 30603, 32004

Ashes 30522

Biological tissues 30522

1

It is the responsibility of the analyst to refer to each analytical method to determine applicability 

of the chosen method to a specific waste type and target analyte. 

2For total decomposition analysis ONLY. 

3For the analysis of samples for hexavalent chromium ONLY. 

4For the analysis of samples for mercury or mercury species ONLY.
SW-846 Update V TWO - 73 Revision 5 

 October 2012 

TABLE 2-45 

USE OF LEACHING, EXTRACTION AND DIGESTION METHODS 

FOR INORGANIC ANALYSIS (In order of increasing strength) 

Method Method Name Reagents & Conditions Use

1310 Extraction Procedure (EP) Toxicity Test 

Method and Structural Integrity Test 

Dilute acetic acid Simulate leaching that would result 

from codisposal of a solid waste and municipal waste in a sanitary landfill

1

1311 Toxicity Characteristic Leaching Procedure Extraction Fluid # 1 -- Dilute glacial acetic 

acid and NaOH, pH 4.93 ± 0.05 Extraction Fluid # 2 -- Dilute glacial acetic acid, pH 2.88 ± 0.05 

Simulate leaching that would result from codisposal of a solid waste and municipal waste in a sanitary landfill

1

1312 Synthetic Precipitation Leaching Procedure Dilute H2SO4 and HNO3 (synthetic acid rain) Simulate acid rain leaching of a waste 

1313 Liquid-Solid Partitioning as a Function of 

Extract pH Batch Extraction Procedure 

Dilute HNO3, KOH Industrial wastes, soils, sludges, 

combustion residues, sediments, stabilized materials, construction materials, and mining wastes 

1316 Liquid-Solid Partitioning as a Function of 

Liquid-to-Solid Ratio in Solid Materials Using a Parallel Batch Procedure 

None Industrial wastes, soils, sludges, 

combustion residues, sediments, stabilized materials, construction materials, and mining wastes 

1320 Multiple Extraction Procedure Dilute H2SO4 and HNO3 (synthetic acid rain) Simulate long-term acid rain leaching of 

a waste 

3005 Acid Digestion of Waters for Total 

Recoverable or Dissolved Metals Analysis by FLAA or ICP Spectroscopy 

HNO3, heat Surface water and groundwater 

3010 Acid Digestion of Aqueous Samples and 

Extracts for Total Metals for Analysis by FLAA or ICP Spectroscopy 

HNO3, HCl, heat Aqueous samples and extracts 

3015 Microwave Assisted Acid Digestion of 

Aqueous Samples and Extracts 

HNO3 or alternatively HNO3 and HCl, 

(pressure, heat) 

Aqueous samples and extracts 
SW-846 Update V TWO - 74 Revision 5 

 October 2012 

TABLE 2-45 (continued) 

USE OF LEACHING, EXTRACTION AND DIGESTION METHODS 

FOR INORGANIC ANALYSIS (In order of increasing strength) 

Method Method Name Reagents & Conditions Use

3020 Acid Digestion of Aqueous Samples and 

Extracts for Total Metals for Analysis by GFAA Spectroscopy 

HNO3, heat Aqueous samples and extracts for 

GFAA work only 

3031 Acid Digestion of Oils for Metals Analysis by 

Atomic Absorption or ICP Spectrometry 

Potassium permanganate, H2SO4, HNO3, 

HCl, heat 

Oils, oily sludges, tars, waxes, paint, paint sludge, and other viscous petroleum products 

3040 Dissolution Procedure for Oils, Greases, or 

Waxes 

Solvent (e.g., xylene, kerosene, or MIBK) Dissolution of oils, oily wastes, greases 

and waxes 

3050 Acid Digestion of Sediments, Sludges, and 

Soils 

HNO3 and H

O2 2, heat 

(for GFAA or ICPMS) HNO3, H

O2 2, and HCl, heat (for ICP-AES or 

FLAA) 

Sediments, soils, and sludges 

3051 A Microwave Assisted Acid Digestion of 

Sediments Sludges, Soils, and Oils 

HNO3, or alternatively HNO3 and HCl, 

microwave assisted (pressure, heat) 

Sludges, sediments, soils and oils 

3052 Microwave Assisted Acid Digestion of 

Siliceous and Organically Based Matrices 

HNO3, HF, HCl (optional) H

O2 2 (optional), 

heat, pressure 

Siliceous, organic and other complex matrices for total sample decomposition 

3060A Alkaline Digestion for Hexavalent Chromium Na2CO3/NaOH, heat Soils, sludges, sediments and some 

industrial wastes for the analysis of hexavalent chromium only.

1 As described in the respective background documents developed in support of the rulemakings which added required use of these methods to 

the Toxicity Characteristic regulation (Method 1311 replaced Method 1310 for Toxicity Characteristic determinations on March 29, 1990, 55 FR 

11862). 
SW-846 Update V TWO - 75 Revision 5 

 October 2012 

TABLE 2-46 

SCREENING METHODS FOR ORGANIC ANALYTES 

 Matrix 

Analyte Type Aqueous Solids 

Sludges and 

Emulsions 

Organic 

Liquids, 

Tars, Oils 

Chlordane 4041 

2,4-Dichlorophenoxyacetic 

acid 

4015 4015 

Hexahydro-1,3,5-trinitro1,3,5-triazine (RDX)  4051 

8510 

 

Octahydro-1,3,5,7-tetranitro1,3,5,7-tetrazocine (HMX)  8510 

Pentachlorophenol 4010 4010 

8540 

4010 

Petroleum Hydrocarbons 4030 

Poly-Chlorinated Biphenyls 

(PCBs) 

4425 

(coplanar) 

4020 

4425 

(coplanar) 

 4020 

(non-aqueous) 

Polychlorinated 

Dibenzodioxins 

4425 4425 

Polychlorinated 

Dibenzofurans 

4425 4425 

Polynuclear Aromatic 

Hydrocarbons (PAHs) 

4425 4035 

4425 

 

Toxaphene 4040 

Triazine Pesticides 4670 

(quantitative) 

 

1,1,1,-Trichloro-2,2-

bis(chlorophenyl)ethane 

(DDT) and breakdown 

products 

 4042 

Trinitrotoluene (TNT) 4050 

8515 

 
SW-846 Update V TWO - 76 Revision 5 

 October 2012 

Sample

Is sample

 to be analyzed for

extractables or

volatiles?

Physical

characteristic of

sample.

Sample Prep:

5030, 5031, 5032,

8011

Sample Prep:

3585

Analysis

Procedure?

Volatile

Aqueous Liquid

Sample Prep:

5021, 2032, 5035

Solid or Sludge

Organic Liquid or Oil

GC/MS Anaylsis

Procedure:

8260, 8261

GC/MS

GC Analysis Procedures:

EDB and DBCP: 8011

Nonhalogenated Volatile Compounds: 8015

Halogenated Volatile Compounds: 8021

Acrylonitrile: 8031

Acrylamide: 8032

Acetonitrile: 8033

HPLC Analysis Procedures:

Acrolein, Acrylonitrile, Acrylanide: 8316

Carbaryl Compounds: 8315

GC

HPLC

Dioxin?

Physical

characteristic of

sample.

Extraction

Procedure:

3510, 3520, 3535

Extraction

Procedure:

3540, 3541, 3545,

3546, 3550, 3560,

3561, 3562, 3580

Is cleanup

needed?

Extractable

Aqueous Sample

Extraction

Procedure:

3650 or 3580

Organic Liquid

Oil

Solid

Cleanup Procedures:

Alumina Column: 3610

Alumina Column for Petroleum Wastes: 3611

Florisil Column: 3620

Silicia Gel Column: 3630

Gel Permeation: 3640

Acid Base Partitioning: 3650

Sulfure: 3660

Sulfuric Acid Cleanup: 3665

HPLC Analysis Procedures:

8310, 8318, 8321, 8325,

8330, 8331, 8332

Yes

No

Yes 8280 or 8290

No

Does the

sample need

extraction?

No

Yes

Analysis

Procedure?

GC/MS

Procedure:

8270, 8275

GC/MS

HPLC

GC Analysis Procedures:

Phenols: 8041

Phthalate Esters: 8061

Nitrosamines: 8070

Organochlorine Pesticides: 8081, 8085

PCBs: 8082

Nitroaromatics and Cyclic Ketones: 8091

Explosives: 8095

Polynuclear Aromatic Hydrocarbons: 8100

Haloethers: 8111

Chlorinated Hydrocarbons: 8121

Organophosphorus Pesticides: 8085, 8141

Chlorinated Herbicides: 8151

GC

FIGURE 2-1 

ORGANIC ANALYSIS OPTIONS FOR SOLID AND LIQUID MATRICES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 for information on the flexibility inherent in 

SW-846 methods. 
SW-846 Update V TWO - 77 Revision 5 

 October 2012 

FIGURE 2-2 

SCHEMATIC OF SEQUENCE TO DETERMINE 

IF A WASTE IS HAZARDOUS BY CHARACTERISTIC
SW-846 Update V TWO - 78 Revision 5 

 October 2012 

FIGURE 2-2 (continued) 

(continued) 

 
SW-846 Update V TWO - 79 Revision 5 

 October 2012 

FIGURE 2-3A 

 RECOMMENDED SW-846 METHODS FOR ANALYSIS OF EP LEACHATES 
SW-846 Update V TWO - 80 Revision 5 

 October 2012 

FIGURE 2-3B 

RECOMMENDED SW-846 METHODS FOR ANALYSIS OF TCLP LEACHATES 
SW-846 Update V TWO - 81 Revision 5 

 October 2012 

FIGURE 2-4A 

 GROUNDWATER ANALYSIS - ORGANIC ANALYTES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 for information on the flexibility inherent in 

SW-846 methods. 
SW-846 Update V TWO - 82 Revision 5 

 October 2012 

FIGURE 2-4B 

 GROUNDWATER ANALYSIS - INDICATOR ANALYTES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 regarding the flexibility inherent in SW-846 methods.
SW-846 Update V TWO - 83 Revision 5 

 October 2012 

FIGURE 2-4C 

 GROUNDWATER ANALYSIS - INORGANIC ANALYTES 

For illustrative purposes only. See the disclaimer and Sec. 2.1 regarding the flexibility inherent in SW-846 methods. 
SW-846 Update V TWO - 84 Revision 5 

 October 2012 

Appendix A: Summary of Updates/Changes in Chapter 2

1. Improved overall method formatting for consistency with new SW-846 methods style 

guidance. The entire document was reformatted in Microsoft Word 2007.docx format 

from the original .WPD and .PDF files. 

2. The Revision number was changed to Revision 5, updated for release October 2012. 

3. A Table of Contents was compiled and added to make finding information easier. 

4. Minor editorial and grammatical changes such as, removing extra spaces between 

words, adding commas, etc. were made throughout sections 1.0 to 2.7. The disclaimer 

statement in Section 1.0 was numbered to keep the format consistent, as it started at 

section 2.0 originally. 

5. Graphics in the Figures Section were modified from Corel Drawing Objects V.10 to .jpg 

graphical images where needed to remove artifacts from the conversion process. The 

text titles of each figure was centered and formatted. 

6. This Appendix was added to document non-significant changes made during the 

editorial process. 

7. Bis(2-choroisopropyl) ether was corrected to Bis(2-chloro-1-methylethyl) ether in Tables 

2-1, 2-4, 2-15, 2-22, and 2-34. 

8. Revised Table 2-40(A) to reflect current sample preservation guidance for styrene and 

vinyl chloride in aqueous samples (i.e., deletion of previously recommended practice of 

collecting a second set of samples without acid preservatives and analyze immediately, 

if styrene and vinyl chloride are analytes of interest).. 

9. Revised Table 2-41. 

10. Revised Table 2-45 to include Methods 1313 and 1316. 

11. Added Table 2-46. 

12. Added Figure(s) for new leaching procedure(s). 

13. Revised Table 2-40(B) to include Mercury Speciation hold times in addition to totals.