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  <xs:element name="RestructuringChargesAmountPayableInCommonStockShares" id="pgnx_RestructuringChargesAmountPayableInCommonStockShares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" abstract="false" xbrli:periodType="instant" />
  <xs:element name="MaximumLicenseFeeReceivableOnCommencementOfUSOrExUSPhase3TrialOfPro140" id="pgnx_MaximumLicenseFeeReceivableOnCommencementOfUSOrExUSPhase3TrialOfPro140" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" />
  <xs:element name="MaximumLicenseFeeReceivableUponUSOrEUMarketingApprovalOfPro140" id="pgnx_MaximumLicenseFeeReceivableUponUSOrEUMarketingApprovalOfPro140" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" />
  <xs:element name="EligibleToReceivePro140Abstract" id="pgnx_EligibleToReceivePro140Abstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" abstract="true" xbrli:periodType="duration" />
  <xs:element name="ProceedsFromLicenseFeesReceivedPro140" id="pgnx_ProceedsFromLicenseFeesReceivedPro140" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" />
</xs:schema>
</XBRL>