## Cover Letter

The ePMN file was too large and could not be processed properly by CDX at the EPA. Therefore the PMN is being submitted in pieces through CDX. Therefore, six toxicity and environmental studies are being sent as supplemental data even though they are part of this original submission and really are attachments to the PMN file. The SNUN substance has been in commerce globally since 2001 as 3M(TM) Novec(TM) 7000 Engineered Fluid. The original PMN submission (P-01-320) was followed by a SNUR (68 FR 70181, 40 CFR 721.8145) restricting use to the original PMN applications - heat transfer fluid and refrigerant - in addition to a production volume cap of 100 MT/yr. In 2004, a SNUN (S04-2) was submitted for use of Novec 7000 as an aerosol cleaning solvent which was granted; an increase in the volume cap was not requested by 3M at that time. {XXX} Several new toxicology and environmental studies concerning this chemical have been generated since the original PMN submission in 2001, some were submitted with the 2004 SNUN submission and others are included in this submission. 3M believes the results of these studies should alleviate most, if not all, of the human health concerns the EPA had with the original PMN submission resulting in the issuance of the SNUR. {XXX}

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### 1000225261 NOVE101007481808630 GG0610

X X X X
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Page 3 SANITIZED SUBMISSIONBriana Hagen Regulatory Specialist 3M Company 3M Center, Bldg. 236-1B-10 St. Paul MN 55144-1000 blhagen@mmm.com

Glen Giacoletto Regulatory Specialist 3M Company 3M Center, Bldg. 236-1B-10 St. Paul MN 55144-1000 gmgiacoletto@mmm.com 651-736-4544 

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## X

Propane, 1,1,1,2,2,,3,3-heptafluoro-3-methoxy375-03-1 

## X C4H3F7O See Attachment 001 (SNUN Substance Chemical Structure.pdf)

SNUN Substance Chemical Structure.pdf Page 5 SANITIZED SUBMISSIONPage 6 SANITIZED SUBMISSIONPage 7 SANITIZED SUBMISSIONPage 8 SANITIZED SUBMISSIONXXX

methyl perfluoropropyl ether, Novec HFE-7000, Novec 7000 

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XXX XXX 

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## (1)

XXX XXX 

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X Flush cleaning XXX 

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### X 0 0 100 0 Foam blowing XXX 

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### X 0 0 100 0 Deposition coating XXX 

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### X 0 0 100 0 Histology baths XXX 

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## (1)

Vapor degreasing XXX 

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XXX XXX XXX 

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XXX 

## X 3M Cordova 22614 Route 84 North Cordova Rock Island IL 61242

Page 13 SANITIZED SUBMISSIONSee Attachment 002 (SNUN Substance Manufacturing Flow Diagram Santized.doc)

SNUN Substance Manufacturing Flow Diagram Santized.doc Page 14 SANITIZED SUBMISSIONPage 15 SANITIZED SUBMISSIONXXX XXX XXX XXX XXX 

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XXX XXX XXX 

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XXX 

## X 3M Cordova 22614 Route 84 North Cordova Rock Island IL 61242

Page 17 SANITIZED SUBMISSIONSee Attachment 003 (SNUN Substance Processing Flow Diagram Santized.doc)

SNUN Substance Processing Flow Diagram Santized.doc Page 18 SANITIZED SUBMISSIONXXX XXX XXX XXX XXX XXX 

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## X

See Attachment 004 (Deposition Coating.pdf)

Deposition Coating.pdf XXX 

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Page 21 SANITIZED SUBMISSIONP10SB1(a)(4)1 Part II, Section B, 1(a)(4). Operation Site Locations

XXX

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See Attachment 005 (Flush Cleaning.pdf)

Flush Cleaning.pdf XXX 

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Page 24 SANITIZED SUBMISSIONP10SB1(a)(4)2 Part II, Section B, 1(a)(4). Operation Site Locations

XXX

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XXX 

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1 None None



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2 Trace 

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## X

See Attachment 007 (Vapor Degreasing.pdf)

Vapor Degreasing.pdf XXX 

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Page 29 SANITIZED SUBMISSIONP10SB1(a)(4)4 Part II, Section B, 1(a)(4). Operation Site Locations

XXX

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XXX XXX XXX XXX



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## X

See Attachment 006 (Histology.pdf)

Histology.pdf XXX 

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Page 32 SANITIZED SUBMISSIONP10SB1(a)(4)5 Part II, Section B, 1(a)(4). Operation Site Locations

XXX

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Page 34 SANITIZED SUBMISSIONThe SNUN material has now been in commerce globally for several years. It is part of 3M's family of hydrofluoroether-based enginnering fluid

products that in several applications have successfully replaced CFC, HCFC and PFC substances that have high global warming potentials, long atmospheric lifetimes and/or are ozone depletors. Due to it's unique chemical and physical properties, the SNUN substances has found utility in additional applications to replace PFCs (e.g., various perfluoroalkanes and perfluoroamines), CFCs ( e.g., trichloroethylene, perchloroethylene, methylene chloride), or flammable ( e.g., isopentane, acetone) substances which is the purpose of this SNUN application. The SNUN substance has been recognized by the EPA's Significant New Alternatives Policy (SNAP) as an acceptable alternative for CFCs and HCFCs in various heat transfer, refrigeration, and precision/electronics cleaning applications.

Page 35 SANITIZED SUBMISSION001 Structure SNUN Substance Chemical Structure.pdf Pt.I, Sec.B, 1e. 1 002 SNUN Substance Manufacturing Flow Diagram SNUN Substance Manufacturing Flow Diagram Santized.doc Pt.2, Sec.A, 1d. 1 003 SNUN Substance Processing Flow Diagram SNUN Substance Processing Flow Diagram Santized.doc Pt.2, Sec.A, 1d. (#2) 1 004 Deposition Coating Deposition Coating.pdf Pt.2, Sec.B, 1a. 1 005 Flush Cleaning Flush Cleaning.pdf Pt.2, Sec.B, 1a. (#2) 1 006 Histology Histology.pdf Pt.2, Sec.B, 1a. (#5) 2 007 Vapor Degreasing Vapor Degreasing.pdf Pt.2, Sec.B, 1a. (#4) 3 008 Novec 7000 MSDS Novec 7000 MSDS.pdf 9 009 Toxicological Assessment Toxicological Assessment TSCA Sanitized.pdf 8 010 Sanit tox zebra fish 96-Hour Acute Toxicity in ZebraFish - Static TSCA Sanitized.pdf 32 011 Sanit Activated Sludge Activated Sludge Respiration Inhibition Test TSCA 13 012 Sanit Acute Eye Irritation Acute Eye Irritation-Corrosion 13 013 Sanitized Daphnia Acute Tox in Daphnia Magna Semi-Static TSCA Sanitized.pdf 28 014 Sanitized Hypersensitivity Contact Hypersensitivity in the Mouse TSCA Santized.pdf 20 015 Sanitized Algal Growth Fresh Water Algal Growth 33

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## X Measured 403 Measured 20 1.4 Measured
< 50 ppm Measured 20 -122.5 Measured 34 Measured 760
3.72 Measured

Not flammable Measured Not explosive Measured
415 C Measured Auto-ignition Temperature Page 37 SANITIZED SUBMISSIONFlash point None Measured

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## ATTACHMENT HEADER SHEET Attachment Number 001 Attachment Name Structure 

## Associated PMN Section Number

Pt.I, Sec.B, 1e. Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 002 Attachment Name SNUN Substance Manufacturing Flow Diagram 

## Associated PMN Section Number

Pt.2, Sec.A, 1d. Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 003 Attachment Name SNUN Substance Processing Flow Diagram 

## Associated PMN Section Number

Pt.2, Sec.A, 1d. (#2) Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 004 Attachment Name Deposition Coating 

## Associated PMN Section Number

Pt.2, Sec.B, 1a. Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 005 Attachment Name Flush Cleaning 

## Associated PMN Section Number

Pt.2, Sec.B, 1a. (#2) Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 006 Attachment Name Histology 

## Associated PMN Section Number

Pt.2, Sec.B, 1a. (#5) Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 007 Attachment Name Vapor Degreasing 

## Associated PMN Section Number

Pt.2, Sec.B, 1a. (#4) Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 008 Attachment Name Novec 7000 MSDS 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 009 Attachment Name Toxicological Assessment 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 010 Attachment Name Sanit tox zebra fish 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 011 Attachment Name Sanit Activated Sludge 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 012 Attachment Name Sanit Acute Eye Irritation 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 013 Attachment Name Sanitized Daphnia 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 014 Attachment Name Sanitized Hypersensitivity 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630

## ATTACHMENT HEADER SHEET Attachment Number 015 Attachment Name Sanitized Algal Growth 

## Associated PMN Section Number

N/A Does not contain CBI 

## Report Number NOVE101007481808630