1 Subject: FW: Re: 2012 paper in AJE on autonomic and vascular dysfunction

Attachments: IQRs in Cardiac study in AJE 2012.xlsx

From: Wei Huang [ mailto:whuang@pku.edu.cn ]

Sent: Thursday, May 09, 2013 6:26 AM

To: Luben, Tom

Cc: tzhu

Subject: Re: 2012 paper in AJE on autonomic and vascular dysfunction

Hi Tom:

Enclosed please find the summary of IQRs applied in the estimates in Table 4 and 5. Yes,

different IQRs were developed and used for the dif ferent ave raging time, for each of the

pollutants and the outcomes. Let me know if you have any questions.

Best wishes,

Wei

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To: Tom" "Luben < Luben.Tom@epa.gov >

From: Wei Huang < whuang@pku.edu.cn >

Cc: tzhu < tzhu@pku.edu.cn >

Date: Wed, 08 May 2013 20:24:14 +0800 (CST)

Subject: Re: 2012 paper in AJE on autonomic and vascular dysfunction

Hi Wei,

Thank you very much for your quick response. I was able to locate the IQRs for the 4

‐ h r MA.

In looking through the results, it appears as though the IQR for the 12

‐ hr avg was 48.4,

This led me to believe that different IQRs were used for each of the different averaging

times for each of the different pollutants. I'm specifically interested in the IQRs used for

the 1

‐ hr and 12

‐ hr results in Table 4 and the 30

‐ min, 2

‐ hr, 12

‐ hr and 24

‐ hr results in Table

5. I would really appreciate any information you could provide regarding these results.

Thank you,

Tom

Tom Luben, PhD

National Center for Environmental Assessment Office of Research and De velopment U.S.

Environ mental Protection Agency RTP, NC 27711

(919) 541

‐ 5762

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From: Wei Huang [ mailto:whuang@pku.edu.cn ]

Sent: Wednesday, May 08, 2013 5:36 AM

To: Luben, Tom

Cc: tzhu

Subject: Re: 2012 paper in AJE on autonomic and vascular dysfunction2 Tom:

During the study period, the IQRs for 4

‐ hr MA PM2.5, BC, NO2, SO2, CO, and O3 were:

51.84, 2.02, 13.7, 6.3, 0.66, 36.15 (10

‐ hour max values of hourly ozone was used in the

estimates)

Thank you for your interest in our work, and let us know if you hav e further inquiry!

Best wishes,

Wei

Wei Huang, ScD

Professor

Dept of Occupational and Environmental Health Peking University School of Public Health

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From: Zhu Tong < tzhu@pku.edu.cn >

To: Tom' 'Luben < Luben.Tom@epa.gov >

抄送 : whuang@pku.edu.cn

Date: Tue, 07 May 2013 21:04:42 +0800 (CST)

Re: 2012 paper in AJE on autonomic and vascular dysfunction

Dr. Luben,

I am also sending this email to my colleague, Dr. Wei Huang, the first author of this paper,

for responding to your request.

Best

Tong

Tong Zhu, Dr.

Professor, College of Envir onmental Sciences and Engineering Director, Centre for Environment

and Health Peking University, Beijing 100871, China Tel:+86

‐ 10

‐ 62754789 ; Fax:+86

‐ 10

‐ 62760755

< http://cese.pku.edu.cn > http://cese.pku.edu.cn

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From: Luben, Tom [ mailto:Luben.Tom@epa.gov ]

Date: Tuesday 2013 May 7 21:01

To: tzhu@pku.edu.cn

From: 2012 paper in AJE on autonomic and vascular dysfunction

Dr. Zhu,

I have been reviewing your 2012 paper, "Air pollution and autonomic and vascular dysfunction

in patients with cardiovascular disease: interactions of systemic inflammation, overweight,

and gender" (AJE 176(2): 117

‐ 126), for inclusion in our upcoming Integrated Science

Assessment on Oxi des of Nitrogen. I was able to find the IQR that you used for the 4

‐ h

effect estimates in Table 4, but was hoping that you could send me the IQR values used for

the other exposure periods in Tables 4 and 5?

Thank you,

Tom Luben, PhD

Epidemiologist, N ational Center for Environmental Assessment U.S. Environmental Protection

Agency

### PM2.5 BC NO2 SO2 CO O3

IQRs in Table 4 (HRV)

1hr 55.87 2.25 15.2 5.7 0.67 39.95

4hr 51.84 2.02 13.7 6.3 0.66 36.15

12hr 48.38 1.93 10.9 6.2 0.66 28.03

IQRs in Table 5 (BP)

30min 56.9 1.26 14.49 6.52 0.47 30.62

2hr 57.4 1.18 13.24 5.6 0.49 33.79

12hr 45.5 0.88 8.28 4.29 0.36 34.03

24hr 32.3 0.9 6.91 2.25 0.22 21.29