**Exhibit 31.1**

 

**CERTIFICATION**

 

I, Steven B. Rash certifythat:

 

1.                           Ihave reviewed this quarterly report on Form 10-QSB of Power3 MedicalProducts, Inc.;

 

2.                           Basedon my knowledge, this report does not contain any untrue statement of amaterial fact or omit to state a material fact necessary to make the statementsmade, in light of the circumstances under which such statements were made, notmisleading with respect to the period covered by this  report;

 

3.                           Basedon my knowledge, the financial statements, and other financial informationincluded in the this  report, fairlypresent in all material respects the financial condition, results of operationsand cash flows of the small business issuer as of, and for the periodspresented in this  report;

 

4.                           Thesmall business issuer’s other certifying officer(s) and I are responsible forestablishing and maintaining disclosure controls and procedures (as defined inExchange Act Rules 13a-15(e) and 15d-15(e)) for the small businessissuer and have:

 

a.                                       Designedsuch disclosure controls and procedures, or caused such disclosure controls andprocedures to be designed under our supervision, to ensure that materialinformation relating to the small business issuer, including its consolidatedsubsidiaries, is made known to us by others within those entities, particularlyduring the period in which this  reportis being prepared;

 

b.                                      Evaluatedthe effectiveness of the small business issuer’s disclosure controls andprocedures and presented in this report our conclusions about the effectivenessof the disclosure controls, as of the end of the period covered by this reportbased on such evaluation;; and

 

c.                                       Disclosedin this report any change in the small business issuer’s internal control overfinancial reporting that occurred during the small business issuer’s mostrecent fiscal quarter (the small business issuer’s fourth fiscal quarter in thecase of an annual report) that has materially affected, or is reasonably likelyto materially affect, the small business issuer’s internal control overfinancial reporting; and

 

5.                           Thesmall business issuer’s other certifying officer(s) and I have disclosed, basedon our most recent evaluation of internal control over financial reporting tothe small business issuer’s auditors and audit committee of the small businessissuer’s  board of directors (or personsperforming the equivalent functions);

 

a.                                       Allsignificant deficiencies in the design or operation of internal control overfinancial reporting which are reasonably likely to adversely affect the smallbusiness issuer’s ability to record, process, summarize, and report financialinformation; and

 

b.                                      Anyfraud, whether or not material, that involves management or other employees whohave a significant role in the small business issuer’s internal control overfinancial reporting.

 
| Date:  | November 14,  2005 | /s/ Steven B.  Rash                          |   |
|--------|-------------------------|----------------------------------------------|--------|
|   |                    | By: Steven B.  Rash                          |
|   |                    | Title: Chairman  and Chief Executive Officer |

 

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