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EPA REGISTRATION DIVISION COMPANY NOTICE OF FILING FOR PESTICIDE PETITIONS PUBLISHED IN THE FEDERAL REGISTER EPA Registration Division contact: W. Cutchin 703 - 305 - 7990 INSTRUCTIONS: Please utilize this outline in preparing the pesticide petition. In cases where the outline element does not apply, please insert “NA - Remove” and maintain the outline. Please do not change the margins, font, or format in your pesticide petition. Simply re place the instructions that appear in green , i.e., “ [ insert company name ] ,” with the information specific to your action. TEMPLATE: Stepan Company 2E8000 EPA has received a pesticide petition 2E8000 from Stepan Company, 22 West Frontage Rd., Northfield Illinois 60093 request ing, pursuant to section 408(d) of the Federal Food, Drug, and Cosmetic Act (FFDCA), 21 U.S.C. 346a(d), to amend 40 CFR part 180 to establish an exemption from the requirement of a tolerance for α - (ρ Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) (CAS No.: 37251 - 69 - 7 ; Mn = 1889 Daltons) when used as a pesticide inert ingredient as a surfactant in pesticide formulations under CFR part 180.960 in or on all raw agricultural c ommodities without limitations . EPA has determined that the petition contains data or information regarding the elements set forth in section 408 (d)(2) of FDDCA; however, EPA has not fully evaluated the sufficiency of the submitted data at this time o r whether the data supports granting of the petition. Additional data may be needed before EPA rules on the petition. A. Residue Chemistry 1. Plant metabolism. Stepan Company is petitioning that α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7; Mn=1889 Daltons ) be exempt from the requirement of a tolerance based upon the definition of a low - risk polymer under 40 CFR 723.250. Therefore, plant metabolism in treated crops is not relevant. 2. Analytical method . Stepan Company is petitioning that α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7; Mn=1889 Daltons ) be exempt from the requirement of a tolerance based upon the definition of a low - risk polymer under 40 CFR 723 .250. Therefore, an analytical method to determine residues on treated crops is not relevant.2 3. Magnitude of residues. Stepan Company is petitioning that α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene ) ( CAS# 37251 - 69 - 7; Mn=18 89 Daltons ) be exempt from the requirement of a tolerance based upon the definition of a low - risk polymer under 40 CFR 723.250. Therefore, magnitude of residues on treated crops is not relevant . B. Toxicological Profile 1. Acute toxicity. No toxicological data is submitted with, or referenced in this tolerance exemption petition because α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7; Mn=1889 Daltons ) meets the definition of a low - risk polymer und er 40 CFR 723.250. 1 a . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 is a polymer molecule as defined by 40 CFR 723.250(b). That is, it contains a sequence of at least 3 monomer units which are covalently bound to at least one other monomer unit or other reactant. 1b . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 has a number average molecular weight of 1889 and contains less th an 0.1 percent oligomeric material below molecular weight 500 and 1,000 molecular weight. 1c . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 is not a cationic polymer and is not anticipated to become a cationic polymer in a natural aquatic environment. 1d . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 only contains the elements carbon, hydrogen, and oxygen; therefore, it meets the c riteria for elemental composition. 1e . The polymer does not contain as an integral part of its composition, except as impurities, any element other than those listed in 40 CFR 723.250(d)(2)(ii). 1f . α - (p - Nonylphenyl)poly(oxypropylene) block polymer wit h poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 is not designed or reasonably anticipated to substantially degrade, decompose, or depolymerize under normal use conditions. 1g . Fatty α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyet hylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 is not manufactured or imported from monomers and/or other reactants that are not already included on the TSCA Chemical Substance Inventory or manufactured under an applicable TSCA section 5 exemption. 1h . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 is not a water - absorbing polymer with a number average molecular weight above 10,000 daltons. 1i . α - (p - Nonylphenyl)poly(oxypropylene) block polymer wi th poly(oxyethylene); Mn=1889 Daltons; CAS# 37251 - 69 - 7 contains no reactive functional groups that fail to meet the low - risk polymer exemption criteria under 40 CFR 723.250(e). ]3 2. Genotoxicty. Not applicable - remove. 3. Reproductive and developmental toxicity. Not applicable - remove. 4. Subchronic toxicity. Not applicable - remove. 5. Chronic toxicity. Not applicable - remove. 6. Animal metabolism. Not applicable - remove. 7. Metabolite toxicology . Not applicable - remove. 8. Endocrine disruption . Not applicable - remove. C. Aggregate Exposure 1. Dietary exposure. The physical and chemical characteristics of α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ) lead to the conclusion that there is a reasonable certainty of no harm from exposure to the polymer from food or drinking water. i. Food. Not applicable - remove. ii. Drinking water . Not applicable - remove. 2. Non - dietary exposure . The physical and chemical characteristics of α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ) lead to the conclusion that there is a reasonable certainty of no harm from exposure to the polymer t hrough non - dietary means. D. Cumulative Effects α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ) is a low - risk polymer. There is no information at this time to suggest that any toxic effects produced by this inert ingredient would be cumulative with any other chemical . E. Safety Determination 1. U.S. population. α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ) meets all the criter ia for qualification as a low - risk polymer under 40 CFR 723.250. Adverse effects on the U.S. population are not expected from the use of this inert ingredient in pesticide formulations. 2. Infants and children . α - (p - Nonylphenyl)poly(oxypropylene) block polymer with poly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ) is a low - risk polymer4

under 40 CFR 723.250. No adverse effects are expected from use of this inert ingredient in pesticide formulations. Based on the physical and chemical properties of the molecule, there is no reason to believe that infants and children will be disproportionately at risk. F. International Tolerances There are no known U.S. or international tolerances for α - (p - Nonylphenyl)poly(oxypropylene) block polymer with po ly(oxyethylene) ( CAS# 37251 - 69 - 7 ; Mn=1889 Daltons ).