NUREG/CR-4884 '. 

BNL-NUREG-52063 

IAt~~pretation of c~"" ' 

Br~.a~say Measurements 

:;~<" . ;:'" . .,,' 

" ,', !< ", .~;. .. ;,:: 

" : Prepared by 

, , ~', 

Edward 1. Lessard, Xia Yihua, Kenneth W. Skrable, George E. Chabot, 

Clay tonS. French, Thomas R, Labone, John R. Johnson, Darrell R. Fisher, 

Richard Befanger, Joyce Landmann Lipsltein 

Brookhaven National labOratory" 

Upton, Long Island, New York 11973' 

" :'.~ 

Prepared for 

~,U .S .. N~c1.ear Regulatory 

" CommlSSlon " , 

i 

Reprinted May 1988 
I 

I nterpretationof 

Bioassay Measurements 

Manuscript Completed: June 1987 

Date Published: July 1987 

~r .. n"'rA" by 

... n'>l\lAI~n T, Lessard, Brookhaven National Laboratory. Upton. New York 

Xia Yihua. Institute of Atomic Energy. Beijing. People's Republic of China 

Kenneth W. Skrable. University of Lowell. Lowell. Massachusetts 

George E. Chabot. University of Lowell. Lowell. Massachusetts 

Clayton S. French. University of Lowell, Lowell. Massachusetts 

ThomasR. Labone, University of Lowell. Lowell, Massachusetts 

John R. Johnson. Chalk River Nuclear Laboratory, Ontario. Canada 

Darrell R. Fisher. Battelle Pacific Northwest Laboratory, Richland. Washington 

Richard Belanger, Science Applications International Corporation, San Diego, California 

Joyce Landmann Lipsztein, Commissao Nacional de Energia Nuclear. Sao Paulo. Brazil 

NRC Project Managers - B.G. Brooks and A. Brodsky 

Prepared for 

Division of Regulatory Applications 

Office of Nuclear Regulatory Research 

U.S. Nuclear Regulatory Commission 

Washington, DC 20555 

NRC FIN A-3289 

NUREG/CR-4884 

BNL-NUREG-52063 
NOTICE 

This report was prepared as an accoun t of work sponsored by an agency of the United 

States Government. Neither the United States Government nor any agency thereof,or 

any of their employees, makes any warranty, expressed or implied, or assumes any 

legal liability or responsibility for any third party's use, or the results of such use, of 

any information, apparatus, product or process disclosed in this report, or represents 

that its use by such third party would not infringe privately owned rights. 

The views expressed in this report are not necessarily those of the U.S. Nuclear 

Regulatory Commission. 

Available from 

Superintendent of Documents 

U.S. Government Printing Office 

P.O. Box 87082 

Washington, DC 20013-7982 

and 

National Technical Information Service 

Springfield, Virginia 22161 
ABSTRACT 

This is a comprehensive manual describing how to compute intakes 

from both in-vivo and in-vitro bioassay measurements. To date, 

interpretations of intake have been inconsistent, particularly in 

the early phases after an accidental intake. This manual is aimed 

at completely describing a consistent approach and instructing 

others on how to compute intakes and committed organ dose equi valents. Tables for the interpretation of bioassay results are 

compiled for several hundred radionuclides. Measurements which 

employ a whole-body counter, a thyroid counter, a lung counter, or 

measurements on excreta can be converted into estimates of intake 

based on the tables presented in the appendices. The values in the 

tables were determined by using lung, gastrointestinal tract and 

systemic retention models published by the International Commission 

on Radiological Protection (ICRP79). In a few cases, pseudoretention functions, organ retention functions, and excretion 

functions were used to generate the tabulated values. The biological and radiological input parameters are included in an appendix, 

and a description of the mathematical approach that was used to 

derive the tabulated data is included in the methods section. 

Calculations for various particle sizes are addressed along with 

methods to interpret multiple or continuous exposures. Examples of 

use are based on actual bioassay measurements following accidental 

intakes, including tritium, Mn-54, Co-60, Sr-90, Nb-95, radioiodines, Cs-137, Ce-141, Ce-144, U-233, U-Nat, and Am-241. 

iii 
CORTENTS 

ABSTRACT ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• 111 

LIST OF FIGURES ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• viii 

LIST OF TABLES •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• ix 

PREFACE ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• x1 

ACKNOWLEDGMENT •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• xiii 

1. INTRODUCTION •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• 1 

1.1 Problems Associated with Internal Dose Assessment •••••••••••••••••• 1 

1.2 Criteria for Selecting This Approach, Literature Reviewed, 

Validation and Verification Methods •••••••••••••••••••••••••••• 2 

1.3 Premise of the Manual •••••••••••••••••••••••••••••••••••••••••••••• 3 

2. DESCRIPTION OF CALCULATIONAL METHOD •••••••••••••••••••••••••••••••••••••• 4 

2.1 Introduction ••••••••••••••••••••••••••••••••••••••••••••••••••••••• 4 

2.2 Terminology Needed for Interpretation of Bioassay 

Measurements ••••••••••••••••••••••••••••••••••••••••••••••••••• 6· 

2.3 Limitations Associated with Use of Metabolic Models •••••••••••••••• 9 

2.4 Intake Retention Functions and Their Applications •••••••••••••••••• 9 

2.5 Catenary Pathways from Intake to Excretion •••••••••••••••••••••••• 10 

2.5.1 Radioelement Intake Retention Function in(t) 

for the nth Catenary Compartment ••••••••••••••••••••••••••• 15 

2.5.2 Inhalation Intake Retention Functions for Lungs •••••••••••• 16 

2.5.2.1 Inhalation Intake Retention Functions for 

GI Tract and Accumulated Feces •••••••••••••••• 16 

2.5.2.2 Inhalation Intake Retention Functions for the 

Systemic Whole Body and Urinary Excretion 

for Stable Cobalt ••••••••••••••••••••••••••••• 17 

3. RETENTION AND EXCRETION FRACTION TABLES ••••••••••••••••••••••••••••••••• 21 

3.1 Description of Tables ••••••••••••••••••••••••••••••••••••••••••••• 21 

3.2 Best Estimate of Intake from Several Bioassay Measurements •••••••• 22 

4. USE OF RETENTION FRACTIONS TO CALCULATE INTERNAL DOSE ••••••••••••••••••• 23 

4.1 An Example of Use for Inhalation of Class D 1-131 ••••••••••••••••• 23 

5. DESIGN AND CONDUCT OF A BIOASSAY PROGRAM •••••••••••••••••••••••••••••••• 25 

5.1 Derived Investigation Levels •••••••••••••••••••••••••••••••••••••• 25 

5.2 Frequency of Monitoring ••••••••••••••••••••••••••••••••••••••••••• 26 

5.3 Table of Derived Investigation Levels ••••••••••••••••••••••••••••• 27 

6. GENERAL EVALUATION •••••••••••••••••••••••••••••••••••••••••••••••••••••• 33 

6.1 Validation of Tabulated Results ••••••••••••••••••••••••••••••••••• 33 

v 
6.1.1 

6.1.2 

6.1.3 

6.1.4 

6.1.5 

General Description of the REMedy Model •••••••••••••••••••• 33 

General Description of DOSEDAY and DOSEYR •••••••••••••••••• 34 

Input Values for Validation Tests •••••••••••••••••••••••••• 34 

Validation Results ••••••••••••••••••••••••••••••••••••••••• 35 

Conclusions Drawn ,from Validation Study •••••••••••••••••••• 36 

6.2 Applications and Limitations of IRF Values •••••••••••••••••••••••• 48 

6.2.1 Pitfalls Associated w/Interpreting Bioassay Measurements ••• 48 

6.3 Recommendations for Further -Study ••••••••••••••••••••••••••••••••• 50 

7. SUMMARy ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• 51 

8. BIBLIOGRAPHy •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• 52 

APPENDIX A - EXAMPLE OF USE AND VERIFICATION BASED ON EXPERIENCES •••••••••• A-1 

1. INTRODUCTION ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• A-1 

2. INHALATION OF CLASS D URANIUM •••••••••••••••••••••••••••••••••••••••••• A-2 

3. INHALATION OF CLASS D Cs-137 AND CLASS W Co-60 ••••••••••••••••••••••••• A-5 

4. RADIOIODINE INGESTION AND INHALATION ••••••••••••••••••••••••••••••••••• A-6 

5. IN~LATION OF THORIUM AND URANIUM •••••••••••••• ~ •••••••••••••••••••••• A-11 

6. EXPOSURE TO TRITIUM •••••••••••••••••••••••••••••••••••••••••••••••••• A-14 

7. VERIFICATION OF INHALATION AND INGESTION MODELS FOR Mn-54, Co-60 

Sr-90, Nb-95, Cs-137, Ce-141, Ce-144, U-233, and Am-241 ••••••••••• A-15 

8. BIBLIOGRAPHY ••••••••••••••••••••••••••••••••••••••••••••••••••••••••• A-30 

APPENDIX B - TABULAtED DATA •••••••••••••••••••••••••••••••• ~ ••••••••••••••• B-1 

1. INTRODUCTION ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• B2. 

3. 

4. 

5. 

6. 

7. 

1.1 Class D Tables Listed by Atomic Number ••••••••••••••••••••••••••• B-2 

1.2 Class W Tables Listed by Atomic Number ••••••••••••••••••••••••••• B-4 

1.3 Class Y Tables Listed by Atomic Number ••••••••••••••••••••••••••• B-6 

1.4 Ingestion Tables Listed by Atomic Number ••••••••••••••••••••••••• B-7 

1.5 Biological and Radiological Parameters Listed by Atomic Number ••• B-9 

TABLES OF RETENTION AND EXC.RETION FRACTIONS FOR SINGLE 

INHALATION OF CLASS D AEROSOLS OF 1 MICROMETER AMAD ••••••••••••••••••• B-12 

TABLES OF RETENTION AND EXCRETION FRACTIONS FOR SINGLE 

INHALATION OF CLASS W AEROSOLS OF 1 MICROMETER AMAD •••••••••••••••••• B-164 

TABLES OF RETENTION AND EXCRETION FRACTIONS FOR SINGLE 

INHALATION OF CLASS Y AEROSOLS OF 1 MICROMETER AMAD •••••••••••••••••• B-359 

TABLES OF RETENTION AND EXCRETION FRACTIONS FOR SINGLE INGESTION ••••• B-·467 

TABLES OF RETENTION AND EXCRETION FRACTIONS FOR SINGLE INTAKE 

OF C-14 DIOXIDE, C-14 MONOXIDE, AND U-3 WATER OR VAPOUR •••••••••••••• B-708 

BIOLOGICAL AND RADIOLOGICAL PARAMETERS USED IN THIS STUDY ••••• ~.~ •••• B-712 

vi 
8. RETENTION FRACTION FOR SIZE DISTRIBUTIONS OTHER THAN 

1 MICROMETER AMAD •••••••••••••••••••••••••••••••••••••••••••••••••••• B-800 

9. RETENTION FRACTION FOR MULTIPLE AND CONTINUOUS INTAKES OF 

SELECTED NUCLIDES ••••••••••••••••••••••••••••••••••••• · ••••••••••••••• B.-803 

10. BIBLIOGRAPHy ••••••••••••••••••••••••••••••••••••••••••••••••••••••••• B-808 

11. ALPHABETICAL INDE~ TO APPENDIX B ••••••••••••••••••••••••••••••••••••• B-809 

vii 
i· 

LIST 01' PIGIJ.RES 

2.1 Catenary pathways from intake to excretion •••••••••••••••••••••••• 12 

2.2 Inhalation intake retention functions for lungs for 1 micrometer AMAD aerosols of stable Class D, W, or Y compounds •••••••••• 18 

2.3 Inhalation intake retention functions for GI tract and 

accumulated feces for 1 micrometer AMAD aerosols of stable 

Class D, w, or Y compounds for which f1 and ff equal zero ••••••••• 19 

2.4 Systemic retention and urinary excretion post single 

inhalation intake of 1 micrometer AMAD aerosols of stable 

Class W, cobalt for which f1 = 0.05 and fu = 0.8 •••••••••••••••••• 20 

viii 
LIST OF TABIBS 

4.1.1 Example of Intake Estimate for Iodine-HI Exposure 

Using Two Different Measuring Devices and Thyroid IRFs ••••••••••• 24 

5.1.1 Derived Investigation Levels for Urine Samples and Time Post 

Intake of Class W, 1 Micrometer AMAD Aerosols of 

70.8 Day Co-58 ••••••••••••••••••••••••••••••••••••••••••••••••••• 26 

5.3.1 Derived Investigation Levels for an Acute Intake ••••••••••••••••• 28 

6.1.1 Validation of Inhalation Results for Excreta Measurements •••••••• 37 

6.1.2 Validation of Inhalation Results for In Vivo Measurements •••••••• 43 

6.1.3 Validation of Ingestion Results •••••••••••••••••••••••••••••••••• 46 

6.1.4 Validation of Thyroid Retention Results •••••••••••••••••••••••••• 47 

ix 
PREFACE 

The purpose of this report is to provide a practical and consistent method for 

estimating intakes from bioassay measurements, and to provide guidance in 

order to establish an effective internal radiation protection program. Our 

procedure for estimating intakes provides a way to rapidly assess the significance of an exposure. Users of this document will be able to demonstrate 

compliance with the provisions of 10CFR Part 20, and be able to assure adequate interpretation of bioassay measurements. Additionally this report may 

be useful in order to (1) establish derived investigation levels in the body 

or in excreta of exposed persons, (2) determine the frequency of monitoring 

individuals, and (3) determine the appropriate method of monitoring. Users of 

this document will be able to adjust their estimate of intake for particle 

sizes between 0.2 and 10 micrometers, and be able to interpret measurements 

associated with single, DJ.lltip1e or continuous intakes. Use of this report 

may also lead to further refinement of models which are used to interpret 

bioassay measurements. 

xi 
i . 

I 

The authors would like to thank Mr. Robert E. Alexander, Office of Nuclear 

Regulatory Research, United States Nuclear Regulatory Commission, for having 

the vision and initiative to appreciate the need for this work, to obtain the 

funds for it, and to recommend a group to work on the project. 

We wish to express our sincere appreciation for the scientific review and 

sound advice from Dr. Allen Brodsky, Program Manager, Radiation Risk 

Management, Nuclear Regulatory Commission, and from Dr. John Baum, Associate 

Head for Research, Safety and Environmental Protection Division, Brookhaven 

National Laboratory. Additionally, we wish to thank Barbara Brooks, Program 

Manager, Office of Nuclear Regulatory Research, Nuclear Regulatory Commission, 

for helping to bring this program to completion. 

We wish to acknowledge the contributions of the following persons and thank 

them for a job well done. They are: E.P. Hope, C.L. Clary, and B.E. 

Kirstein, Science Applications International Corporation; we thank them for 

modifying and applying the REMedy and DOSEDAY/OOSEYR programs for use in the 

validation effort. We also thank Marie Cooney, Br90khaven National Laboratory 

for typing the manuscript, and Cheryll Christie for assisting in this work. 

xiii 
INTEllPRETATION OF BIOASSAY HEASOBEHEIITS 

1. IITRODUCTION 

1.1 Problems Associated with Internal Dose Assessment 

The estimation of internal radiation doses from radionuclides taken into the 

body, either by workers or by members of the public, often depends on the 

proper interpretation of bioassay measurements. Measurements of radioactivity 

in body organs or in the whole body (in vivo), or measurements in samples of 

excretion (in vitro), must be interpreted first in terms of the quantity of 

radioactive material taken into the body by using dynamic mathematical models 

that describe the translocation, distribution and elimination of specific 

radionuclides in specified physical and chemical forms. Although area air 

sampling results can provide estimates of intake for demonstrating compliance 

with regulatory limits, they are unreliable and inaccurate if exposure to 

concentrations vary in space and in time. In such cases, personnel monitoring 

procedures such as breathing zone air sampling and bioassay should be used for 

the estimation of intakes by workers (Ca 72). After known or suspected exposures have occurred or when the potential for such exposures is sufficiently 

great, bioassay has been required as a final quality control procedure under 

the provisions of 10CFR Part 20 (FR86) in order to assure adequate functioning 

of the air monitoring program and other elements of the internal radiation 

protection program. 

Dose conversion factors have been calculated from ICRP Publication 30 and 

other models by various authors, and these factors are available to convert 

estimated or assumed intakes into 50 year committed doses to various body 

organs or into the so called committed effective dose equivalent to the whole 

body. However, the models of ICRP Publication 30 used in these calculations 

do not provide for excretion compartments. Thus, they do not provide a direct 

way to calculate intakes from excreta bioassay measurements. Intake 

calculations from bioassay measurements were found to be in demand after the 

Three Mile Island accident as well as after other significant cases of human 

intake of radioactive material by workers. Such calculations are made not 

only to determine compliance with applicable regulations on intake of radioactive material but a~o to provide continued refinement of estimates of 

internal dose. Such dose estimates may be needed for both early emergency 

medical decisions and long-term medical follow up of significantly exposed 

workers. 

To date, the interpretations of bioassay data in terms of intakes have been 

made using various empirical models that have often produced inconsistent 

estimates, particularly in the early emergency phases after an accidental 

intake. The guide we have developed provides a consistent approach to calculating intakes of all important radionuclides from bioassay measurements. 

In this guide we describe these calculations and present tables of values for 

intake retention functions, thus providing a practical and consistent way of 

computing intakes from both in vivo and in vitro bioassay measurements. 

For each radionuclide included in Appendix B, intake retention fractions 

(IRFs) for the inhalation of ICRP Publication 30 Classes D, W, ·and Y materials 

are provided. Similar IRF values are given for ingestion intakes. The 

1 
tabulated values in Appendix B include the decay factor. The lRF values are 

applicable to whole-body and lung measurement results as well as the results 

from urine and fecal analyses. A table of lRF values for the thyroid is 

provided for converting the results of thyroid measurements into estimates 

intake of iodine isotopes. Methods for extending the use of the tables to 

include conditions of multiple and continuous intakes and for aerosols havi 

a particle size distribution other than 1 micrometer Activity Median 

Aerodynamic Diameter (AMAD), as used in lCRP Publication 30, are given. 

1.2 Criteria for Selecting this Approach, Literature Reviewed, Validation and 

Verification Methods 

The computational method used here was selected because it was recently 

documented and illustrated in publications by Skrable (Sk80, Sk81, Sk83). 

Methods for solving for quantities associated with compartmental models, using 

microcomputers and algorithms, have also been described by Birchall (Bi86), 

and he indicates a specific algorithm, using BASIC, which executes in seconds. 

Skrable (Sk81), on the other hand, has written programs using Hewlett Packard 

language on the HP41CV for solving the retention and excretion of inhaled or 

ingested materials. The serial-transformation kinetics equation used by both 

these authors requires that all pathways leading to a compartment of interest 

be defined. Thus, many applications of the equation are needed to follow a 

nuclide through the body. Without computers these computations would be 

tedious. In addition, recent compilations have become available (ICRP74, 

ICRP77, ICRPS3), which are specific for radiation protection, for standard 

radiological and physiological parameters that describe a radionuclide's fate 

in the body of a reference adult male. Thus, the computational approach for 

lRFs was selected based on the availability of current models and parameters, 

plus the availability of computers. 

The ease of computing intakes, on the other hand, can be improved from the 

availability of tabulated values of the lRFs for both in vivo and in vitro 

bioassay compartments. The data in these tables are obtained by repetitive 

application of algorithms similar to those supplied by Birchall and Skrable. 

In addition, tabular data giving the intake retention fractions, expected to 

be present in various bioassay compartments are helpful in choosing a bioassay 

procedure. 

In ICRP Publication 30 (ICRP79), the whole-body systemic uptake retention 

functions in many instances are expressed as a sum of exponential terms. 

Because of this and because this suited our approach, the criteria used to 

select an excretion or systemic uptake retention expression was that it be 

expressed as an exponential or sum of exponentials. Exponential functions are 

suitable for models which incorporate feedback and recycling of an element 

such as those for iodine and those used in this manual for the alkaline earth 

elements. In this study, we use a pseudo-retention function for plutonium 

based upon an excretion function recently reported by Jones (J085).' Exponential models were fitted to the alkaline earth metabolism described in ICRP 

Publication ,20 (ICRP72) based upon a model .reported by Johnson and Myers (in 

Sk83), and we used these fitted functions for Ca,Sr, Ba and Ra. These models 

duplicate the ICRP Task Group's retention function (lCRP72) over the period 

0.1 day to 20,000 days post intake but they are used here since they are appropriate functions for the computational method developed by Skrable (Sk83). 

For all other elements the whole-body systemic uptake ret~ntion functions 

2 
ICRP Publication 30 were used. We note that the iodine metabolism suggested 

by Riggs (Ri52) was used here, and we caution users of ICRP Publication 30 

(ICRP74) that the correct description of the Rigg's whole-body systemic uptake 

retention function for iodine appears in an Addendum to ICRP Publication 30 

(ICRP81). 

The Dosimetric Research Branch, Chalk River Nuclear Laboratory (CRNL), has 

been monitoring employees and others for internal contamination and interpreting the results in terms of dose using ICRP or other models for more than 

35 years. When ICRP Publication 26 introduced the committed effective dose 

equivalent and annual limits on intake in 1977, they initiated a complete 

review of models and procedures for interpreting internal contamination 

monitoring. Part of this review involved the development of computer codes 

and data bases to carry out detailed calculations. These computer codes and 

data bases contain the latest ICRP recommended models and parameters as well 

as other models, as appropriate. For the most part, they contain the metabolic models and parameters and dosimetric data used in ICRP Publication 30. 

These facilities at CRNL were used to validate the tabulations of retention 

and excretion fractions listed in this document. 

Researchers at Science Applications International Corporation (SAIC) have been 

involved in the development of computer programs to' predict retention and 

excretion from ICRP 30 metabolic models for the last three years. As part of 

the quality control process used in the production of this document, selected 

tabular results were validated by comparison to results predicted by SAIC 

models for the same assumed set of conditions. Two SAIC programs were used in 

the validation tests. These programs, which are described in Section 6.1, 

were developed by different individuals and feature completely different 

computational approaches. One is a Pascal-language program which incorporates 

an analytic solution algorithm much like the BNL model employed to generate 

the tabular values. The other is a BASIC program which employs Runge-Kutta 

numerical integration techniques. 

The SAIC validation process involved comparison of inhalation and ingestion 

retention results for the following radionuclides: Fe-59, Co-60, Sr-90, 1-131, 

Cs-137, Ce-144, Th-232 , U-235, Pu-239, and Am-241. This process was valuable 

in identifying programming or computational errors in the draft results. 

After correction of identified errors, very good agreement was reached between 

the tabulated results and those generated by the other programs. 

Actual case studies were used to verify the models used in this report, and 

these studies were presented in Appendix A. Dr. Darrell Fisher, from Battelle 

Pacific Northwest Laboratories, and Dr. Joyce Landmann Lipsztein, from 

Brazil's National Commission for Nuclear Energy, provided most of this work 

based on their. experiences. These case studies included: (1) inhalation of 

Co-60, Mn-54 , Sr-90, Ce-141, Ce-144, U-233, Am-241, 1-131, thorium and natural 

uranium and (2) ingestion of Co-60, Nb-95, Cs-137, Ce-141, Ce-144, Sr-90 and 

1-131. Additionally, several case studies based on the experiences of staff 

from Brookhaven National Laboratory were included. 

1.3 Premise of the Manual 

The estimate of intake of radioactive material depends on the proper interpretation of bioassay measurements, and Qften the method for interpretation is 

poorly documented. Because the interpretation of bioassay data involves many 

3 
physical relationships between a multitude of variables, part of the problem 

of interpretation involves this complexity. In some cases, refinement of the 

interpretation may continue for years after the initial assessment of the 

intake and dose equivalent. Thus, a proper approach to interpretation is to 

establish a clear record of the methods used throughout the assessment. We 

intend this manual to provide an easy to use method, yet one that incorporates 

the complexity of current mathematical models. This obviously leads to 

certain limitations that must be recognized, e.g., the use of Reference Man or 

other standard models for estimating the intakes by actual workers. We 

provide a detailed description of the approach as well as practical examples. 

When significant exposures occur, we encourage others to perform more detailed 

investigations that could provide data useful in the validation or improvement 

of the models and approaches used in this report. 

2. DESCRIPTION OF CALCULATIONAL METHOD 

2.1 Introduction 

This section describes a way to obtain intake retention functions. These 

functions give the fraction of an intake of radioactive material expected to 

be present in a bioassay compartment at any time aFter an acute exposure or 

after onset of a continuous exposure. The intake is estimated from the 

quotient of the quantity of a radionuclide measured in a bioassay compartment 

by the intake retention fraction for that compartment. The intake can be 

compared to the NRC quarterly intake limit, the ICRP Publication 30 Annual 

Limit on Intake, or with other appropriate reference levels. This procedure 

for estimating intakes provides for a rapid assessment of the Significance of 

measured results and thus provides a way to distinguish between exposures that 

require further investigation from exposures that do not. The model is based 

upon Reference Man models which are summarized in ICRP Publications 23 and 30 

(ICRP74, ICRP79), but other metabolic models that fit the ICRP structure also 

can be used. The bioassay compartments may represent specific physiological 

entities such as the lungs or the gastrointestional tract, total body or 

excreta. Intake pathways which we consider here include inhalation and ingestion. We discuss the estimation of intakes and internal radiation doses and 

the frequency of monitoring required for detection. Our approach to Qbtaining 

intake retention functions can be implemented into any bioassay monitoring 

program that employs measurements on people or measurements of excreta. 

Intake retention functions that are based upon Reference Man can be used to 

make a rapid assessment of the committed effective dose equivalent and the 

committed organ or tissue dose equivalent. The quotient of the estimated 

intake by the stochastic Annual Limit on Intake (ALI) value, which is given in 

ICRP Publication 30, when multiplied by 0.05 Sv (5 rem), gives the committed 

effective dose equivalent of an exposed worker. 

One may also obtain organ or tissue dose equivalent by computing the product 

of the intake and the committed dose equivalent in target organs or tissues 

per intake of unit activity. A weighting factor representing the ratio of the 

risk arising from irradiation of the organ or tissue to the total risk when 

the whole body is irradiated uniformly may be multiplied by the committed 

organ or tissue dose equivalent. The sum of the weighted committed dose 

equivalents in target organs or tissues is the committed effective dose 

equivalent. The factors for dose equivalent per unit activity intake (Sv per 

Bq) appear in supplements to ICRP Publication 30. Age and gender averaged 

4 
weighting factors appear in lCRP Publication 26 (ICRP77), but under certain 

circumstances they may be modified to reflect competing causes of death or 

reflect the gender of the exposed person. Thus, a more direct estimate of 

weighted committed, or committed organ and tissue, dose equivalent may be made 

from the estimate of intake and the Sv per Bq factors. 

Nuclear facilities are designed so that combined exposures to people from 

external and internal radiation sources are maintained below the lCRP and the 

proposed NRC committed dose limits (See ICRP77 or NRC84). It is important that 

internal dose assessment procedures, as well as investigation, action, and 

recording reference levels be established with respect to these committed dose 

limits. A quantity derived from these committed limits is the Annual Limit on 

Intake given by ICRP. To assure that significant internal radiation exposures 

are detected, properly investigated, and recorded, all internal radiation dose 

assessment procedures should be designed to translate measurements into 

estimated intakes. Otherwise, significant doses, for example the dose to the 

lungs, may be neglected if only the systemic burden is estimated from excretion bioassay measurements. Because of the direct relationship between intake 

and committed dose, the use of intake provides a way to combine external and 

internal doses. Thus, the total committed organ dose or the committed 

effective dose equivalent to the whole body can be estimated for exposures 

received by workers during each year of practice. 

The detection of an intake that is significant with respect to the ALI may 

require monitoring of both the working environment and the worker. Neither 

bioassay nor air sampling are mutually exclusive; both may be required for an 

accurate assessment of internal radiation exposures (Sk85). When bioassay 

procedures do not have the required sensitivity and accuracy, then breathing 

zone air-sampling should be used to estimate intakes by workers having a 

potential for significant exposures. Accurate assessments of exposures often 

require a proper balance between monitoring the environment and monitoring 

workers. Additionally, information on the physical and biochemical 

characteristics of radionuclides, which can be obtained from monitoring the 

working environment, may be used with Reference Man metabolic models to 

generate intake retention functions that are needed for the estimation of 

intakes from bioassay data. 

Intake retention functions, which give the fractions of an intake expected in 

various in vivo and in vitro bioassay compartments at any time, provide 

necessary information for a rapid and efficient determination of the significance of bioassay results. In addition, intake retention functions can be 

used in the design and operation of a bioassay program. For example, numerical values obtained for intake retention functions can be used to identify 

those bioassay procedures that have sufficient sensitivity. They also can be 

used to calculate derived investigation levels. Following accidents, values 

for intake retention functions can be used to identify special bioassay procedures that confirm and improve estimates of intake. 

In the following, we discuss applications of intake retention functions, 

including some of their limitations. The text includes derivations of these 

functions, derivations which are made via the application of a single catenary 

kinetics equation to a multi compartmental model. These derivations are based 

upon models that describe the transport and retention of elements from intake 

to excretion. The recursive nature of the catenary kinetics equation facili5 
tates programming on calculators or computers. Details related to the 

derivation of various types of intake retention functions and details related 

to fitting of repetitive bioassay measurements are also provided. 

Sections 2.2 through 2.5 provide a detailed description of the calculational 

procedures used to derive the tabulations of intake retention fractions for 

use with in vivo and in vitro measurements. The main points of the 

description are: 

1. the tables, which are derived from the equation given in Section 

2.5.1, give the fraction of intake retained, the fraction excreted in 

24 hours, and the fraction accumulated in excreta as a function of 

time post intake; 

2. intakes can be estimated by dividing the measured value, for lung, 

thyroid, whole-body, urine or fecal activity, by the IRF value which 

is associated with the compartment of interest; 

3. derived investigation levels can be set below which no action is 

required, and above which further measurement to estimate committed 

effective dose equivalent should be made; and 

4. it is unrealistic to assume that individual results will fit model 

results in most exposure cases. The magnitude of the uncertainity is 

indicated in Appendix A, Example of Use Based on Experiences. 

If you require a detailed description of the calculational method, please read 

Sections 2.2 to 2.5, otherwise, advance to Section 3, Retention and Excretion 

Fraction Tables. 

2.2 Terminology Needed for Interpretation of Bioassay Measurements 

There are various quantities or terms used by health physicists for bioassay 

and internal dose assessment and various retention functions have been 

associated with these quantities. The definitions of these quantities are 

important in order to understand the mathematics used in the derivation. 

Terms or quantities include intake, uptake, depOSition, and content: 

intake 

uptake 

depOSition 

content 

fundamental 

= quantity of a radioelement taken into the body by 

inhalation, ingestion, or wound, 

- quantity of a radioelement taken up by the systemic 

circulation, e.g., by injection into the blood, by 

absorption from compartments in the respiratory or GI 

tracts, or by absorption near the site of a wound, 

= quantity of a radioelement deposited, e.g., in the 

respiratory tract following an acute inhalation intake or 

in the stomach following an ingestion intake, 

z quantity of a radioelement present in some bioassay 

compartment of the model, which may be an organ, a group 

of tissues, the whole body, or an excretion compartment. 

rate constant = the instantaneous fractional rate of removal of the 

content of a compartment by biological processes only. 

6 
Each type of retention function applies to the content of a particular 

compartment, relative to the referenced quantity. Thus, each type of function 

yields the fraction of an intake, uptake, or a deposition expected in the 

compartment at some time t, post an intake, uptake, or deposition, respectively. In general, upper case letters are used as symbols in equations in 

order to represent quantities for stable elements while lower case letters are 

used to represent quantities for radionuc1ides. Subscripts are used to 

identify compartments. 

Consider an acute inhalation intake of radioactive aerosols in which 63% of 

the inhaled activity is expected to deposit in the lungs. The initial 

fraction of the intake expected to be deposited in the lungs, which is given 

by the intake retention function for the lungs for t equal 0, is 0.63, while 

the initial fraction of the deposition expected to be present in the lungs, 

which is given by the deposition retention function for the lungs for t equal 

0, is 1.0. The uptake retention function gives the fraction of an acute 

uptake expected in some compartment at some time after an uptake. The values 

of the uptake retention functions for the systemic whole body and the extracellular fluid must equal 1.0 for t equal O. The values of the uptake retention functions for peripheral tissues and organs must equal 0 for t equal O. 

Another important term is fundamental rate constant. Removal can involve 

excretion from the body or simply return to extracellular fluid. A fundamental rate constant can be associated with any organ or tissue. These 

fundamental rate constants may be difficult to determine because a portion of 

the deposition once removed from an organ may be returned to that organ at 

some later time. Thus, a measured rate of loss from the organ would appear to 

be slower than the fundamental rate of loss because small amounts of material 

may be recycled back to the organ. 

The uptake retention function is a mathematical construct or empirical function that may have several exponential terms. Under certain conditions some 

of these terms may be associated with physiologically identifiable compartments. One term in the construct may represent the central compartment if 

there is no significant recycling. The central compartment may be vaguely 

defined as the compartment which includes blood and extracellular fluid, i.e. 

material in this compartment is free-moving. The remaining terms in the 

mathematical construct may be associated with peripheral organs, such as bone 

or thyroid. Material in these compartments includes that contained in cells 

plus that attached to organ surfaces. Again, this physiologic association is 

purposely vague and applies only if there is no significant recycling. 

If the metabolic process, which describes the removal of a radioelement from a 

compartment, is described by linear first-order kinetics, then the deposition 

retention function is given by a single exponential term, with coefficient of 

unity. This simple deposition retention function gives the fraction of 

deposition expected at some later time. This type of deposition retention 

function is used for the stomach for intake via ingestion as well as some 

compartments within the respiratory tract. 

If the retention of a systemic organ or tissue is simple, then the organ's 

deposition retention function is given by a single exponential term, with a 

coefficient of unity_ The function represents the fraction of a single 

deposition expected at some time after deposition, neglecting any recycling of 

7 
the element. However, because of recycling, such deposition retention 

functions would not describe the actual content of organs or tissues. 

If there is no direct excretion from an organ, the fundamental biological ra 

constant, which is a term in the exponent of an organ deposition retention 

function, describes the transfer of a stable element to the central 

compartment. The deposition retention function of a single organ may be given 

by a single exponential term, but on the other hand, the uptake retention 

function for that same organ, will often be given by a sum of exponential 

terms with constant coefficients. The algebraic sum of these coefficients 

must equal 0 at t equal O. A number of peripheral organ and tissue compartments could each have a simple deposition retention function described by a 

single exponential term containing a characteristic fundamental rate 

constant. The value of this rate constant would characterize total biological 

removal to direct excretion or the central compartment. 

If significant recycling of the stable element occurs, then the uptake retention functions for each peripheral compartment and for the central compartment 

would contain the same number of exponential terms. However, rate constants 

in these exponential terms would not equal the fundamental rate constants. In 

the case of recycling, the uptake retention function of each compartment and 

the uptake retention function of the systemic whole body would have the same 

exponential terms but different coefficients. If significant recycling does 

occur, the rate constants in the uptake retention function for the systemic 

whole body do not describe the actual retention of a deposition within a 

specific compartment. These rate constants are effective rate constants, 

which account for recycling of a contaminant between the central and 

peripheral compartments. In such a case, no single exponential term can in 

reality be associated with a particular structured compartment (Sk80). 

If there is no significant recycling, the rate constants in the uptake 

retention functions equal the fundamental rate constants. In such a case, the 

stable element uptake retention function for the central compartment would be 

given by a single exponential term. This central compartment term would 

contain the fundamental rate constant that describes removal by all pathways. 

In the case of no significant recycling, the uptake retention function for a 

stable element for each peripheral organ compartment would contain two exponential terms, one with the fundamental total removal rate constant for the 

central compartment and one with the total biological removal rate constant 

for the organ. In such a case, the individual exponential terms in the uptake 

retention function for the systemic whole body could be associated with 

specific tissues or organs. 

The description of the distribution and retention of elements in ICRP 

Publication 30 (ICRP79) has descriptive simplifications that relate to 

recycling. Because individual exponential terms of most retention functions 

cannot be associated with specific organs, care must be exercised in using the 

ICRP Publication 30 description for the development of bioassay models which 

are needed to make an initial assessment of the significance of bioassay 

data. Additionally, we do not include the ICRP so called "transfer compartment" in the derivation of our intake retention function. The ICRP adds this 

transfer compartment for mathematical convenience (ICRP79) while in fact the 

retention of any transfer compartment must already be included in the systemic 

whole body, empirical, uptake retention function. 

8 
2.3 Limitations Associated With The Use Of Metabolic Models 

Many assumptions are required to translate bioassay data into estimates of 

intakes and internal radiation doses. Such assumptions may include parameter 

values for the fraction of systemic excretion passing into the bioassay excretion compartment as well as assumptions regarding uptake following deposition 

of the radionuclide in the respiratory tract. Because of the physical. 

chemical, and biological complexities that affect the distribution of a radionuclide within the body. neither the annual nor committed effective dose 

equivalent can be obtained from the whole body retention function without 

making many assumptions. Assumptions that may have order of magnitude impact 

apply to single excreta bioassay measurements. This uncertainty can be 

reduced by collecting several samples in sequence. Although frequent and 

careful excreta measurements can be used to obtain the worker's excretion 

function applicable to the time over which measurements are made, many 

assumptions including the physical and biochemical characteristics of the 

inhaled aerosol, the uptake fraction, and the systemic excretion fraction will 

be required for the estimation of intakes and internal radiation doses. 

To estimate the intake and corresponding internal radiation doses, a practical 

alternative is to use information on the known physical and biochemical 

characteristics of inhaled radionuclides, and apply these assumptions to the 

applicable metabolic model for Reference Man. This is the basis for the 

practical use of intake retention functions that are based on Reference Man or 

other appropriate models. 

2.4 Intake Retention Functions and Their A2plications 

Intake retention functions can be used in the design and conduct of bioassay 

programs. They can be used to generate tabular values for stable or radioactive element intake retention fractions (IRFs) as well as derived investigation levels. Such derived investigation levels can provide the operational 

health phYSicist information on procedures which have the required sensitivity 

and accuracy for the minimum amount that can be detected by a given bioassay 

procedure. 

When large accidental exposures occur, attempts should be made to estimate the 

actual retention and dose distribution in the exposed worker rather than rely 

on Reference Man models. ~n such cases, the uncertainties associated with 

using the individual's own metabolic parameters in the estimation of the 

committed doses should be evaluated carefully. , 

When a number of bioassay measurements are used to evaluate an incident, the 

intake retention function. which is derived from Reference Man metabolic 

models, can be used as a fitting function. The amount of the intake is then 

estimated as that which gives the best fit of individual measurements to their 

respective expectation values that are obtained from the product of the estimated intake and values derived from the intake retention fitting function. 

This procedure certainly is justified in most caseswher~ limited and poor 

bioassay data are available. If more extensive and accurate bioassay data are 

available 'from accidental exposure cases, then the residuals obtained from the 

difference between measurements and the expectation values should be examined 

for any apparent structure and discrepancy associated with the use of an 

intake retention fUDction derived from Reference Man models. If large discre9 
pancies are noted, then attempts should be made to improve the assumptions and 

parameter values used to derive the intake retention function used in the fit. 

Committee 4 of the ICRP has published two reports relating to the evaluation 

of radiation doses from bioassay data, Publication 10 (ICRP68) and Publicati 

lOA (IeRP71). These publications are limited to the evaluation of uptakes as 

opposed to intakes. Because of the delay in uptake from compartments in the 

respiratory and GI tracts to the systemic organs, models that incorporate this 

delay in uptake are needed. Specifically, what are needed are intake retention functions, which give the fractions of an intake expected in bioassay 

compartments at various times after an intake. 

2.5 Catenary Pathways from Intake to Excretion 

The metabolism of elements is described here by linear first order kinetics 

which can be depicted as one way transfers between compartments; transfers 

that begin with some intake compartment and end with some excretion 

compartment as depicted in Figure 2.1. The term catenary refers to a one-way 

chain in which material is transfered from one compartment to another. The 

metabolism of all elements can be described in this way. Because the 

metabolism can be described in terms of these simple one way transfers, a 

recursive catenary kinetics equation can be used to obtain the expected 

content of all in vivo and in vitro bioassay compartments. Even though the 

metabolism is described by these one-way tranfers, the intake retention 

functions derived from this model account for recycling within the systemic 

whole body provided that an appropriate whole-body systemic uptake-retention 

function is used in the derivation. An excretion compartment is simply 

treated as the last compartment in each chain. Removal of a radioelement from 

an excretion compartment is described entirely by its radioactive decay 

constant, while total removal from an in vivo compartment is described by the 

sum of the decay constant and all applicable biological removal rate 

constants. It is recognized that this model and description of the metabolism 

is a gross oversimplification of the actual metabolism. 

Provided that appropriate values are chosen and lacking more specific details, 

the catenary model can provide reasonable values for the intake retention 

fractions. On the other hand, care must be exercised in the interpretation of 

the short term kinetics, especially during the first few days following 

accidental intakes. 

Chains of compartments can be determined for inhalation intakes, ingestion 

intakes, instantaneous uptake, or exponential uptake, for example from a 

wound. If several chains lead to a particular compartment of interest, the 

total retention function for that compartment is obtained by summing the 

contributions from all chains. If a system of organs and tissues, such as the 

systemic whole body, is modeled as if it were comprised of a number of 

independent catenary compartments, the total retention function is obtained 

from the sum of retention functions for the individual compartments. 

There are a number of chains for each type of intake and each chain begins 

with an intake compartment and ends with an excretion compartment. Chains 

involving inhalation intakes, with depositions into various regions of the 

respiratory tract, are shown on the upper left, and pathways involving ingestion intakes are shown on the right in Figure 2.1. 

10 
Inhalation involves eight compartments of deposition in the respiratory tract, 

each of which initiates a separate catenary system. Ingestion begins with one 

compartment of deposition, the stomach. 

Arrows leaving a compartment show the specific removal pathways, which are 

characterized by specific translocation rate constants for particular 

pathways. In addition to biological removal, radioelements are removed from 

each catenary compartment by radioactive decay, which is characterized by the 

decay constant for the radioelement. 

Compartments associated with the respiratory tract are shown on the upper left 

hand side of Figure 2.1. The arrows designated by 0NPI, 0TBI, and OpI 

represent depositions in the three regions of the respiratory tract. These 

arrows lead into the nasal passage region (NP), tracheobronchi region (TB), 

and pulmonary region (P) of the respiratory tract. The symbol I represents 

the intake and DNP ' 0TB' and Op represent the fractional depositions. The 

deposition fractions for an inhalation intake of 1 micrometer AMAO aerosols 

are 0.3, 0.08, and 0.25 for the NP, TB, and P regions, respectively. 

Compartments a, c, and e shown on the left-hand side of the respiratory tract 

schematic are cleared directly to the systemic circulation. Compartment h 

represents clearance to the lymph nodes, which are comprised of two compartments i and j. Compartment i clears to the systemic circulation and compartment j is a sink. The only removal from compartment j is by radioactive 

decay. Compartments b, d, f, and g are shown on the right hand side of the 

schematic and are cleared to the stomach. 

The fraction of a deposition cleared by a particular pathway and the 

associated clearance half-time are designated for three chemical compound 

classifications: days (D), weeks (W), and years (Y), which are representative 

of the clearance half-times from compartments e, g, and h in the pulmonary 

lungs. These clearance half-times are 0.5, 50, and 500 days for Class D, W, 

and Y compounds, respectively. However, there is no clearance for compartment 

g for Class D compounds since there is no deposition in it. 

11 
E 

INHALATION 

I 

~ DNPI 

c d 

e 

h 9 

LYMPH NODES 

'---.....--''------''--'-.E 

SYS'E.MIC EXCRETION 

1 F

f 

Ff 

TOTAL EXCRETION COMP. I FECES (5) 

n 

Rs(t): I CiS e-o,t FOR SYSTEMIC 

1~1 WHOLE BODY 

FIGURE 2.1 Catenary pathways from intake to excretion. Respiratory tract 

compartments are a through j. Gastrointestinal tract 

compartments are 1 - 4. RS(t) defines the stable element uptake 

retention function for the systemic whole body which is expressed 

by a sum of exponential terms (i = 1 to n) with constant 

coefficients. 

12 
Shown on the right-hand side of Figure 2.1 are the four segments of the gastrointestinal tract. An ingestion intake is first deposited in the stomach. The 

intake is translocated from one segment of the gastrointestinal tract to 

another and then finally to the feces, which are designated here as compartment 

5. The feces are considered part of the total excretion compartment. In ICRP 

Publication 30, instantaneous uniform mixing and linear first-order kinetics 

are assumed to apply to each segment of the tract. These assumptions result in 

an overestimate of the early fecal excretion. The mean residence time in each 

segment of the tract are 1 hour for the Rtomach, 4 hours for the small intestine, 13 hours for the upper large intestine, and 24 hours for the lower large 

intestine. Partial absorption of a radioelement into the blood is assumed to 

occur only in the small intestine. If the radioelement is completely absorbed, 

absorption is considered to occur from the stomach, and this pathway is shown 

by a broken arrow to the upper right of Figure 2.1. The translocation rate_1 constant that is associated with this pathway is simply set equal to 24 day , 

which is that associated with the removal of the contents from the stomach. 

The inverse of the mean residence time for the contents of each segment gives 

the translocation rate constant for both the contents and contained 

radionuclides. 

Absorption into the syst'emic circulation is shown to lead to a horizontal line 

designated by U, which represents uptake. Absorption into the systemic 

circulation itself is identified by the symbol S. All pathways combine at U 

and then divide into n compartments. These compartments are designated by the 

n exponential terms in the whole-body systemic uptake retention function Rs(t) 

shown at the bottom of Figure 2.1. 

The second translocation rate constant, which describes transfer from a 

compartment that feeds a systemic compartment via uptake into the systemic 

circulation, is obtained by multiplying the first translocation rate constant 

from the feed compartment to the systemic circulation by the coefficient CiS of 

the exponential term in RS(t) that pertains to the pseudo catenary compartment 

of interest. For example, consider an ingestio~ intake where fl = 1 so that 

the translocation rate constant kI,s of 24 day- describes transfer from the 

stomach to the systemic circulation. To obtain the rate constant kl is' which 

describes transfer from the stomach to the is compartment, the rate ~onstant 

kI,s is multiplied by the coefficient CiS for the psuedo catenary compartment 

of interest. 

Each ith exponential term in RS(t) is treated as,a deposition retention 

function of a pseudo catenary compartment, and each compartment is modeled to 

be cleared directly to systemic excretion E" at an ins'tantaneous fractional rate 

given by the effective rate constant ai of the ith exponential term. The 

effective fraction of an uptake U that passes into the ith pseudo catenary 

compartment of the systemic whole body, as noted above, is given by the 

coefficient CiS of the exponential term in RS(t). 

Because the intake retention function Rs(t) embodies, in principle, all of the 

dynamic processes that describe the metabolism of stable elements in the 

systemic whole body, including the recycling of elements, the intake function 

IS(t) which is derived from the function RS(t) also embodies all these metabolic processes plus the metabolic processes that occur in all of the 

compartments ,that feed the systemic circulation. It is fortunate that each 

exponential term of the uptake retention function for the systemic whole body 

13 
can be treated as a deposition retention function for a pseudo catenary compartment. It greatly simplifies the derivation of intake retention functions 

from the general catenary kinetics equation shown as equation 2.5.1 below. 

Atoms of a radioelement that leave one of the pseudo catenary compartments 

the systemic whole body are shown to go directly to systemic excretion, whi 

is deSignated here by a horizontal line identified by E in Figure 2.1. The 

rate constant that describes the fractional rate of excretion from each is 

compartment is the eigenvalue rate constant gi in the exponential exp(-ait) of 

the uptake retention function RS(t). The it exponential term of RS(t) thus 

represents the deposition retention function for the is compartment, and loss 

from this compartment is shown to go directly to excretion. Because parameter 

values in RS(t) are effective values that incorporate recycling, it can be 

shown that this interpretation is mathematically correct. 

The line E is necessary for designating the fraction of excretion that leaves 

the systemic whole body via the fecal excretion pathway, and by all other 

pathways. The fraction ff of systemic excretion via the fecal pathway is shown 

to enter feces directly. The primary pathway is probably that involving 

biliary excretion, which passes into the duodenum or first part of the small 

intestine. The systemic fecal excretion pathway is shown here to bypass the GI 

tract. Thus, the fraction ff of systemic fecal excretion should be considered 

an effective value. 

Although this model simplifies the mathematics, it is not realistic. Because 

of the lack of data for the systemic fecal excretion pathway, this simplifying 

assumption seems reasonable for developing bioassay models. 

All systemic excretion, as well as direct fecal excretion, is shown in Figu 

2.1 to end up in the compartment that is designated as the total excretion 

compartment. This compartment is treated as any other catenary compartment; 

is the last compartment of all catenary systems. The only removal process from 

this compartment is radioactive decay. Thus, the total removal rate constant 

kj that describes removal from this compartment is set equal to the decay 

constant A for a radioele~ent, or zero for a stable element. 

Intake retention functions for acute inhalation can be obtained for specific 

organs, organ systems, and excretion by summing the functions for the appropriate compartments. This includes: (1) the nasal passages, compartments a 

and b; (2) the lungs, compartments c through j; (3) the GI tract, compartments 

1 through 4; (4) the systemic whole body, compartments IS through nS; (5) a 

specific systemic organ x, compartments Ix through nx corresponding to the 

exponential terms in the stable uptake retention function Rx(t) for the organ 

x; (6) the accumulated total systemic excretion, compartment E; (7) the 

accumulated total fecal excretion, compartment 5; (8) the ac~umulated urinary 

excretion, which is obtained from the product of f~ times the intake retention 

function for compartment E if fu is constant; and \9) the total body, which is 

the sum of (1) through (4) above. In the same way as above, intake retention 

functions can be obtained for ingestion intakes, instantaneous uptakes, or 

delayed uptakes through a wound. 

To apply a general catenary kinetics equation, one must identify the appropriate chains of compartments, specify the translocation and total removal rate 

constants within each chain, and specify the decay constant for the radio14 
element. Numerical values for the fraction of an intake expected in a compartment are easily obtained because the same recursive kinetics equation is used 

for each chain that leads to the compartment of interest. 

2.5.1 Radioelement Intake Retention Function in(t) for nth Catenary 

Compartment 

The concise catenary kinetics equation shown here as equation 2.5.1 can be 

applied to all of those catenary pathways that lead to an nth compartment of 

interest to obtain the radioelement intake retention function in(t) for that 

compartment: 

where: 

C 

n-l 

= 1: FC[ II 

C p=1 

n 

kp,p+l [ E 

j=1 

..;;;.e_-k ...... jl....t ___ ] ] 2.5.1 

= 

= 

n 

II (kp -kj ) 

p-l 

p=j 

fraction of g single acute intake of radioelement expected at 

time t in nt compartment, 

one of the chains that leads to the nth catenary compartment 

of interest, 

fraction of intake deposited into the first compartment of 

chain C, 

kp ,p+1 ... rate constant that describes transfer of element from pth to 

(p+l)th compartment, 

= 

-

total rate constant that describes total removal of the 

radioelement from the jth compartment, and given by the sum of 

the total biological removal rate constant Kj and the decay 

constant A of the radionuclide, and 

total rate constant describing removal from pth compartment. 

The subscript n on in(t) is a general numerical index for the compartment of 

interest. For a given catenary pathway that leads to an nth compartment of 

intere~t, n could have one value. For another pathway, the particular compartment of interest could then be symbolized by another value of n or perhaps the 

same value. For example, consider the intake retention function id(t) for 

compartment d in the TB region of the respiratory tract. Three catenary 

systems contribute to the fraction of an inhalation intake that is present in 

compartment d. These are direct deposition for which n=l, translocation to 

compartment d from compartment f for which n=2, and translocation to compartment d from compartment g for which n=2. 

In the case where two different compartments have the same value for transfer 

rate constant, kp ... ki , one can make kp a little different from k., and thus be 

able to use equation z.5.1. The error is the same order of magnitude of the 

15 
difference assumed between kp and k1• Assuming a small difference, <10 E-4%, 

yields accurate results for In (Bi8~). 

The ICRP Publication 30 respiratory tract model provides the parameter value 

needed for the application of equation 2.5.1. The parameter values genera 

depend on the particle size distribution and the compound classification of 

inhaled aerosol. Particles containing a radioelement and soluble materials 

that are translocated from compartments f and g to compartment d are assumed to 

instantaneously mix with the contents of d, which is cleared by translocation 

to the stomach. The translocation to the stomach, S(I), from d is described by 

a translocation rate constant kd l' which can be obtained from the clearance 

half-time of 0.2 days given in ItRP Publication 30 for all compound classes. 

Equation 2.5.1 is summed over three separate chains C in order to obtain the 

intake retention function id(t) for compartment d in the TB region of the 

lungs. The radioelement intake retention function iL(t) for the lungs is 

obtained by repeating this procedure for the other lung compartments c, e, f, 

g, h, i, and j, all of which mayor may not be applicable for each chemical 

compound classification. For example, for the highly transportable compound 

Class D, the clearance pathways designated by f and g are not used. 

2.5.2 Inhalation Intake Retention Functions for Lungs 

Figure 2.2 shows values for the stable element acute intake retention functions 

IL(t) for the lungs for Class D, Class W, and Class Y compounds and for the 

inhalation of 1 micrometer AMAD aerosols by Reference Man. The curves are for 

an intake at time zero. The plots show that in vivo lung counting can be a 

practical bioassay procedure for the highly transportable Class D compounds 

only if measurements are made soon after an exposure incident. Because of 

large and early absorption into the systemic circulation, in vivo whole-body 

counting may be used as an alternative procedure for Class D compounds. 

counting is applicable to Class Y compounds and practical for Class W compounds 

for tens of days post intake. For Class Y compounds, compartment j is a sink 

that will ultimately contain 0.00375 of an inhalation intake of a stable 

element contained in 1 micrometer AMAD aerosols. Thus, the limiting value for 

IL(t) is 0.00375 for stable Class Y compounds. Lung counting would not be a 

practical bioassay procedure for the inhalation of non-respirable particles 

having sizes above about 20 micrometers. However, GI tract counting and/or 

fecal analysis could then be practical. In ,accidental intake cases, these 

curves and a series of lung measurements can be compared in order to estimate 

the compound classes and intakes. 

2.5.2.1 Inhalation Intake Retention Functions for GI Tract and Accumulated 

.. ,,' Feces 

Figure 2.3 shows values for the acute intake retention functions for the GI 

tract contents and for the accumulated feces compartment for Class D, Class W, 

and Class Y compounds. The curves are for an inhalation of 1 micrometer AMAD 

aerosols at a time of zero. The functions were evaluated for the case where 

the fraction fl absorbed into the blood from the small intestine and the 

fraction ff of systemic excretion via the fecal pathway are both zero. 

The plots show that the GI tract segments can contain up to 40% of an inhalation intake of 1 micrometer AMAD aerosols, during the first weeks post in 

16 
. ,.:." 

This fact should be taken into consideration for the proper interpretation of a 

lung count or a whole body count when the GI tract contents contribute 

significantly to the response of the detector. 

The plots show that the accumulated fecal compartment will contain up to about 

60% of an element contained in an inhalation intake of 1 micrometer AMAD 

aerosols. In serious exposure cases, it is recommended that all of the fecal 

excretion over the first five or six days be collected and analyzed. This will 

make the measurements less sensitive to the model assumptions and will give a 

better estimate of the respiratory tract deposition cleared to the fecal 

excretion pathway. 

2.5.2.2 Inhalation Intake ,Retention Functions for Systemic Whole Body and 

Urinary Excretion for Stable Cobalt 

Figure 2.4 shows the expected systemic retention and urinary excretion after a 

single inhalation intake of stable cobalt. The plots apply to Class W compounds and 1 micrometer AMAD aerosols. The ICRP Publicatioq 30 respiratory and 

GI tract models were used to obtain the values for these intake retention 

functions. The systemic whole-body uptake retention function RS(t) given in 

ICRP Publication 30 was used according to the procedure outlined in Figure 

2.1. The value of 0.05 was used for the fraction f1 of stable cobalt absorbed 

from the small intestine into the blood. The value of 0.8 was used for the 

fraction fu of systemic excretion via the urinary pathway. We note that 0.8 

for fu was used based upon a better fit to the reported urine data used to 

obtain the ICRP Publication 30 model for stable cobalt. 

Values that are plotted for stable cobalt include: (1) the systemic whole-body 

intake retention function, which gives the fraction of a single intake that is 

expected to be present in the systemic whole-body at time t post the intake; 

(2) the accumulated urine intake retention function, which gives the fraction 

of intake expected to be present at time t in accumulated urine; (3) the 1 day 

incremental urine intake retention function, which gives the fraction expected 

to be present at time t in an incremental sample of urine that is collected 

from day t-1 to t post intake; and (4) the instantaneous urine excretion rate 

function, which gives the instantaneous fraction of the intake that is expected 

to be excreted per day in the urine at time t post intake. When in vivo or in 

vitro bioassay measurements are made at time t, the intake is estimated by 

dividing the results cOrrected for decay by the value of the applicable stable 

element retention or excretion functions, respectivity, evaluated at t. 

It is not correct to consider an early 24 hour sample as an instantaneous daily 

rate of excretion. As can be seen from Figure 2.4, the incremental function· 

for cobalt exceeds the instantaneous function at early times by a factor of 2. 

Only after about 10 days do values for these two functions come close to one 

another. Thus, a procedure that is used for e~aluating spot urine measurements 

as instantaneous rates of excretion can give high estimates of the intake and 

associated dose equivalent. 

The log-log plots of the urinary excretion of cobalt, following a single acute 

inhalation intake of 1 micrometer AMAD, Class W aerosols, approximate straight 

lines. One might conclude that the underlying metabolism, considering the 

normal variance that is expected in bioassay measurements, is best described by 

a power function in time. However, such a conclusion would be wrong because 

these plots are based upon linear first order kinetics that yield a sum of 

exponential terms with both positive and negative constant coefficients. 

17 
tZ 

lLJ 0.1 (J) 

lLJ 

0::: 

a.. 

z 

0 

tu 0.01 <t 

0::: 

LL 

FIGURE 2.2 

10 100 1000 10000 

TI ME POST INTAKE, days 

Inhalation intake retention functions for lungs for 1 micron 

AMAD aerosols of stable Class D, W, or Y compounds. 

18 
.-

z 

w 

en 0.1 

I.1.J 

cr::: 

0... 

Z 

o 

.-

~ 0.01 

cr::: 

l.L. 

ACCUMULATED 

D FECES 

0.0010.

1 10 100 

FIGURE 2.3 

TIME POST I NTAKE, days 

Inhalation intake retention functions for GI tract and 

accumulated feces for 1 micron AMAD aerosols of stable Class D, 

W, or Y compounds for which f1 and ff equal zero. 

19 
>. 1.0 

0 

"'0 

...... 

0 ACCUMULATED w 

I- URINE 

w 0.1 

0::: 

u 

x SYSTEMIC WHOLE 

w BODY 

0:: 

0 I DAY INCREMENTAL 

I- URINE SAMPLE 

z 

w INSTANTANEOUS FRACTION 

CJ) 

w EXCRETED PER DAY INTO URINE 

0:: 0.001 a.. 

z 

0 

lt) 

~ 0.00011.0 10 

LL 

FIGURE 2.4 

TIME POST INTAKE, days 

Systemic retention and urinary excretion post single 

inhalation intake of 1 micron AMAD aerosols of stable Class W 

cobalt for which f1 = 0.05 and fu -= 0.8. 

20 
The straightness of these excretion curves are fortuitous. In fact, these 

curves embody: (1) the translocation of cobalt in and absorption of cobalt 

from compartments within the respiratory and GI tracts; (2) the delay in uptake 

of cobalt from these compartments; (3) the metabolism of cobalt within the 

systemic whole body including the recirculation of cobalt between cells and 

extracellular fluid; and (4) the final excretion of cobalt from the body, 

partially within urine. 

To make an initial assessment of the significance of bioassay results, we 

recommend the use of intake retention functions that are based upon the ICRP or 

other appropriate Reference Man metabolic models. If the metabolic models are 

based upon the ICRP Publication 30 models, then the assessment will be 

consistent with annual limit on intake and derived air concentration quantities. In serious exposures, appropriate follow-up bioassay procedures should 

be used, along with information on the physical and chemical forms of radionuclides, in order to make a better estimate of the intake and dose and in 

order to provide guidance on possible medical procedures that might be used to 

reduce the committed dose. It would be difficult, in the usual case, to obtain 

values of all parameters for each exposed person. For practicality and other 

reasons, Reference Man metabolic models are best suited to the assessment of 

the significance of the bioassay data of workers in terms of estimated intakes. 

However, if suitable parameter values can be obtained for a specific 

individual, then they should be used to interpret the bioassay measurements, 

and these parameter values should be introduced to the available literature on 

radiation protection. 

3. RETENTION AND EXCRETION FRACTION TABLES 

3.1 Description of Tables 

In the tables in Appendix B, the intake retention fractions are for particular 

in vivo and in vitro compartments of interest at various times after single 

intake. The tables in Appendix B are applicable to inhalation of Class D, 

Class W, and Class Y aerosols of 1 micrometer AMAD or to ingestion intakes. In 

most instances, the IRFs are listed for the stable element plus common radioisotopes of the element. In all, tables for about 200 nuclides are included 

for assessing inhalation and ingestion intakes. The IRFs which are listed for 

Class D, Class W, Class Y and ingestion are in Sections 2, 3, 4 and 5 respectively. All values of IRFs are expressed in exponential notation; for example, 

3.78 E-02 is 0.0378. The IRF values have three significant figures and values 

were rounded originally from calculations which were done using doubleprecision mathematics functions. Time after single intake is given in units of 

days, and in many tables time extends to 20,000 days after a single intake. An 

IRF cutoff of 1.0 E-08 was chosen as an endpoint; thus, the in vivo and in vitro 

IRF values extend to all points in time that may be of practical interest. 

The IRFs apply to in vivo measurements for the systemic organs, lungs, nasal 

passages, gastrointestinal tract and total body. The total body IRFs are the 

sum of IRFs for systemic and non-systemic compartments, and they are useful for 

whole-body counting measurements when the field of view is the total body. For 

example, the IRFs for inhalation of Class W lanthanum 140 for one day after 

intake are 4.75 £-02 for the systemic organs, 1.39 £-01 for the lungs, 3.26 E02 for the nasal passages, 1.75 £-01 for the gastrointestinal tract, and 3.95 

E-Ol for the total body. Thus, nearly 40% of an inhalation intake of 1 micro21 
meter Class W aerosols of lanthanum 140 remains in the total body at one day 

after single intake; 14% of the intake is in the lungs, 18% in the gastrointestinal tract, 3% in the nasal passage, while only 5% has been absorbed 

retained in the systemic region of the body. Since lanthanum 140 is a 

emitter, an in vivo measurement is useful to estimate intake using the 

The intake is estimated by simply dividing the measurement by the IRF. 

Tables of IRFs for excretion compartments are given except for elements that are 

not significantly eliminated from the whole body, for example fluorine. In many 

instances, the IRFs are listed for 24-hour urine, accumulated urine, 24-hour 

feces and accumulated feces. These 24-hour IRF values are incremental values 

while all other IRFs listed in all the tables are instantaneous values. In some 

cases, the fractions of systemic burden excreted via the feces (ff) and the 

fraction excreted via the urine pathway (fu) are unknown. Thus, elimination of 

the uptake is defined as that which goes to a systemic excreta compartment. 

For nuclides with undefined ff or fu' there is an estimate of the portion of the 

intake that is deposited in the respiratory tract and directly eliminated via 

the gastrointestinal tract into the feces. Therefore, IRFs are listed for 24-

hour feces and accumulated feces for that portion of the respiratory tract 

deposit that is not absorbed into the systemic region of the body. In order to 

obtain the total IRF for total excreta, one would add the IRF for systemic and 

non-systemic excreta. For example, the total fraction of intake in a 24-hour 

systemic plus non-systemic sample, which may be the total radioactivity in a 

urinary plus a fecal sample, is 2.79E-02 for inhalation of Class W lanthanum 140 

at one day after single intake. In this case, virtually none of the excreted 

lanthanum 140 comes from the systemic uptake; only 9.22 E-06. In cases where 

the fraction via urine and the fraction via feces are not defined, it may be 

prudent to examine the systemic and non-systemic IRFs which are listed for 

excreta and determine if measurement on feces or urine or both would provide 

adequate information. In this example, measurements on a 24-hour fecal sample 

would suffice for lanthanum 140. 

In many instances, we provide tables which describe IRFs for stable isotopes of 

the elements. These tables may be useful in determining the IRFs for a radioactive isotope of an element, for which there is no tabulation. The approach is 

to multiply the stable IRF by the decay factor associated with the radionuclide. 

For example, the IRF for the total body for stable iodine for 1~ days after 

ingestion is 2.96 E-01. If the nuclide of interest is iodine 125, then the IRF 

is the product of the decay factor evaluated for 10 days of decay and the stable 

iodine IRF or (2.96 E-01) x (8.91 E-01) = 2.64 E-Ol. 

3.2 Best Estimate of Intake from Several Bioassay Measurements 

Following an accidental inhalation or ingestion, several in vitro or in vivo 

measurements for an individual are desirable in order to reduce the propagation 

of the day-to-day variation associated with a sample measurement. A regression 

should be used in order to best fit all the measurements, and the following 

analytical method is recommended: 

I = ~ IRF(i) A(i) 

1: 

i 

3.2 

22 
where: 

I = best estimate of intake with units the same as A(i), 

IRF(i) = intake retention fraction associated with the ith measurement, 

A(i) = value of the ith measurement with appropriate units; for example, 

Bq, ').ICi or pg. 

A more detailed explanation and description of use of equation 3.2 may be 

found in the examples which are covered in Appendix A. 

4. USE OF RETENTION FRACTIONS TO CALCULATE INTERNAL DOSE 

4.1 An Example of Use for Inhalation of Class D 1-131 

The following example illustrates how IRFs may be used to interpret bioassay 

measurements. Additional examples of use of the IRF values for the evaluation 

of actual exposure cases are given in Appendix A. 

A radiopharmicist was measured for 1-131 in the thyroid on May 5, 1986 at the 

whole-body counter at a national laboratory. The measurement followed a 

routine area survey which occurred two days before and which revealed loose 

contamination in the radiopharmacy. The thyroid burden measurement and the 

subsequent discussion with the radiopharmicist indicated to the local safety 

representative and to a health physicist that an inhalation intake of 3.1 E+05 

Bq (8.3 uCi) 1-131 occurred on April 7, 1986, and that some additional 1-131 

was spattered about the work area. The thyroid dose equivalent was initially 

estimated to be 0.091 Sv (9.1 rem) and minor contamination was found on the 

radiopharmicist's car on May 6 and on his clothing on May 7, 1986. The type 

of whole-body counter used to measure thyroid activity was a single large NaI 

crystal which viewed the upper torso in addition to the thyroid. 

The estimated thyroid dose equivalent exceeded the Department of Energy 

quarterly limit of 0.05 Sv (5 rem). On the other hand, it was less than the 

0.5 Sv (50 rem) annual limit recommended by the International Commission on 

Radiological Protection (ICRP), and it was not in excess of the Department of 

Energy annual limit of 0.15 Sv (15 rem). However, it indicated inadequacies 

in the radiation protection program. 

The work was planned to occur in a fume hood. Instead, this work was done in 

a laminar flow cabinet with an exhaust. The guide for laboratory workplace 

standards for dispersible radionuclides indicated to the safety representative 

that a more stringent workplace was required which in this case would have 

been a glove box since the radiopharmicist had no previous experience with 1-

131. Additionally, the April 7th work proceeded in a hurried manner and the 

radiopharmicist may have opened the vial containing 1-131 in the room and not 

in the laminar cabinet, plus he added the wrong reagents. 

The reagent error was corrected the following day but it was done by another 

person, who was unfamiliar with this work and it was done using new techniques, and was the likely cause of the spattered 1-131. All persons associ-

~ted with this work were subsequently checked for contamination but only the 

radiopharmicist was contaminated. Additionally, this work was repeated twice 

on April 22, 1986 in the laminar flow cabinet and the radiopharmicist did not 

23 
have contamination on his hands afterwards. However, all the April 22, 1986 

work was performed according to written procedure and no errors were made. 

The health physicist and safety representative recommended that the foIl 

interim steps be taken immediately but they were not listed in order of 

importance: 

• All sealed vials with MBq (mCi) amounts of 1-131 are to be 

refrigerated prior to opening, are to experience minimal exposure to 

light, and only be opened in a fume hood. Most of the procedure is to 

be performed in a fume hood and the procedure-should be performed by 

trained personnel. 

• The procedure should be written down, and if changed at a later time, 

then the safety representative should be informed. The written 

procedure should be reviewed and approved. 

• A thin-window pancake Gieger~uller instrument should be purchased and 

used in order to check for contamination. The radiopharmicist should 

be trained to monitor hands, clothing, and the work area following 

each work session. The instrument previously used was somewhat 

insensitive to beta, and his monitoring technique needed improvement. 

Subsequent to the initial assessment by the safety representative and the 

health physicist, a formal investigation occurred. It was learned that the 1-

131 compound was a fatty acid and its distribution and retention were different from that chosen for the original dose assessment. Follow-up counting, 

with a multi-crystal whole-body counter, located 40% of the activity fixed in 

the heart and lung regions. Based on the new information, the 1-131 intake 

was reassessed: 

Table 4.1.1 Example of Intake Estiaate for Iodine-131 Exposure 

USing Two Different Measuring Devices and Thyroid IRFs 

Time After 

Accident, 

Days' 

28 

39 

Fraction of 

Intake Retained 

in Thyroid, 

IRFa 

0.0138 

.00505 

Thyroid 

.a_~me~ 

Bq(PCi} 

4.3 E+03 (0.115) 

1.0 E+03 (0.0270) 

Estimated 

Intake, 

Bq(pCi) Comment 

3.1 E+05 (8.3) Single crystal 

torso detector, 

100% in thyroid 

(assumed) 

2.0 E+05 (5.4) Multi-crystal 

whole-body 

detector, 60% in 

thyroid (measured) 

a Fractions obtained from interpolation of values in Appendix B, page B-I03. 

24 
.' .... 

Because the intake could have occurred on April 22nd rather than April 7th, a 

----~urinary sample was taken on the day of the second whole-body count. The ratio 

of measured 24-hour urine activity to thyroid activity was 7.0 E-03. The 

ratio of 24-hour urine IRF to thyroid IRF on day 39 after the accident was 

6.13 E-03. The IRFs for this ratio are obtained from interpolation of the 

values in Appendix B. If the accident occurred on April 22nd, the IRF ratio 

would be 4.9 E-03. Thus, April 7th appeared to be the day of intake. 

However, the metabolism of fatty acid 1-131 has unknown impact on the IRF as 

used in this case, thus the events as described by the radiopharmacist are 

equally important in setting the date of exposure. 

The DOE limit for organ dose equivalent for workers is in terms of quarterly 

and annual dose equivalent, thus the dose conversion factors, Sv/Bq (rem/pCi) 

inhaled, must be in terms of quarterly or annual dose equivalent per Bq (Ci) 

inhaled. For the thyroid, the limits are 0.05 Sv (5 rem) per quarter and 

0.015 Sv (15 rem) per year. However, the half-life of 1-131 is short compared 

to 13 weeks, thus the ICRP Publication 30 value for the committed thyroid dose 

equivalent per unit activity inhaled may be applied in order to estimate organ 

dose equivalent received in one quarter year: 

2.0 E+05 Bq x 2.9 E-07 Sv = 5.8 E-02 SV (5.8 rem) to thyroid -=-""""'!'"-=---=-""""':""-- Bq inhaled 

The remaining activity, which was in the heart and lung regions, appeared to 

decay according to the 8.04 day half-life of 1-131. It was assumed that this 

activity was distributed over a larger mass than that associated with the 

thyroid. Thus, the thyroid activity resulted in the largest organ dose equivalent. By assuming a weighting factor of 0.06, a mass of 332 grams and an 

estimated uptake of 1.9 E+04 Bq (0.52 ~Ci) for the heart, a weighted committed 

heart dose equivalent of 1.1 E-04 Sv (0.011 rem) is computed. Adding this 

value to the weighted thyroid dose equivalent, which is 1.7 E-03 Sv (0.17 rem) 

which is calculated by using a weight of 0.03 (ICRP77), yields a committed 

effective dose equivalent of 1.8 E-03 Sv (0.18 rem). 

S. DESIGN AND CONDUCT OF A BIOASSAY PROGRAM 

5.1 Derived Investigation Levels 

To demonstrate how intake retention functions can be used for the design and 

conduct of a bioassay program, derived investigation levels have.been calculated for 24-hour incremental urine samples. The levels were determined by 

multiplying values of the incremental urine intake-retention function by an 

investigation level based upon 5% ALI, or an investigation level based upon 

the ICRP Publication 26 recommendation of 0.3 x f x ALI, where f is the 

fraction of the year to which the monitoring applies. Values for an inhalation 

intake of Class W, 1 micrometer AMAD aerosols of 770.8 day C~-58 are summarized 

in Table 5.1.1. The value for the ALI is 4 x 10 Bq (1.lx10 uCi), which is 

the stochastic value given in ICRP Publication 30 based upon consideration of 

limiting the risk from stochastic effects to that corresponding to a wholebody committed effective dose equivalent of 0.05 sv (5 rem). Thus, the 5% 

ALI-based derived investigation level corresponds to a committed effective 

dose equivalent of 2.5 mSv (250 mrem) to the whole body of Reference Man. 

Monitoring is assumed to take place every t days post intake; thus, the 

fraction f of the year is calculated here by dividing the time t in days by 

365 days. The daily frequencies of monitoring associated with small values of 

25 
t would not be realistic. However, an investigation is normally triggered by 

a single measurement and it is most appropriate to base the derived investigation level on the fraction of three-tenths of the limit corresponding to the 

fraction of the year to which the monitoring of an individual refers. 

Numerical values are shown for the purpose of comparing these two definit 

of an investigation level. Because the ICRP Publication 26 investigation 

level depends on the frequency of monitoring, the ICRP Publication 26 based 

values first decrease to about 5 days but then increase over a small time 

period before decreasing again. It is noted that NRC has not yet recommended 

these methods of determining derived investigation levels. 

table 5.1.1 Derived Investigation Levels for Urine Samples and Time Post 

Intake of Class W~ 1 Micrometer AMAD Aerosols of 70.8 Day Co-58 

TIME DERIVED INVESTIGATION LEVELS 

POST 

INTAKE 

FRACTION OF 

INTAKE IN 

24-HOUR URINE 

SAMPLE 

FOR 5% of ALI FOR O • .3xfxALI 

Bq (nCi) Bq (nCi) 

1 2. 56E-02 5. 12E04 (1.38E03) 8.41E02 (2. 27EOI) 

2 1.08E-02 2. 16E04 (5.84E02) 7. IlE02 (l.92E01) 

5 2. 16E-03 4.31E03 (I.17E02) 3. 55E02 (9.60EOO) 

7 1. 56E-03 3. 13E03 (8. 47EOI) 3.60E02 (9.74EOO) 

10 I. 15E-03 2.31E03 (6.24EOI) 3.79E02 (I.03E01 ) 

20 5. 47E-04 1.lOE03 (2.96E01) 3.60E02 (9. nEOO) 

100 7.23E-05 1.45E02 (3.91EOO) 2. 38E02 (6.42EOO) 

5.2 Freguencx of Monitoring 

The minimum frequency of monitoring can be determined from the derived 

investigation levels shown in Table 5.1.1. To demonstrate this application, 

suppose that an analytical procedure has a minimum detectable activity of III 

Bq (3 nCi). From values that are summarized in Table 5.1.1 for a constant 

investigation level of 0.05 ALI, the minimum frequency of monitoring is 

approximately every 100 days since the derived investigation level approaches 

the minimum detection limit. Obviously, other factors such as the potential 

for exposure and the exposure history should be considered in the establishment of the bioassay monitoring frequency. If air monitoring data and the 

exposure history of workers show little potential and infrequent and insignificant exposures, the frequency of monitoring can be relaxed. The potentially highest exposed workers can be randomly selected for bioassays as a 

quality control procedure, and operational monitoring can be used to demonstrate the adequacy of the internal radiation protection programs. 

1n considering other factors, the exposure history is important since 

continuous or multiple exposures to nuclides with long half-lives and long 

retentions limit the usefulness of single intake IRFs for the derivation of 

investigation levels. Continuous intake IRF values and corresponding derived 

investigation levels could then be used. However, for most radiation workers 

in nuclear medicine, in nuclear power plants, and in the national laboratories, inhalation and ingestion of radioactive materials are not planned t 

occur; rather, acute intake following an unplanned exposure is encountered 

Thus, single intake IRFs are useful for the derivation of investigation le 

26 
Intake retention functions can be used to determine those routine bioassay 

procedures that have sufficient sensitivity and accuracy for the internal 

radiation protection program. Consider, for example, the appropriateness of 

lung counting for Pu-239 as a routine bioassay procedure. The draft ANSI 13.30 

standard, "Draft Performance Criteria for Radiobioassay," specifies the 

acceptable minimum detectable activity as 190 Bq (5 nCi) L X-rays per nuclear 

transformation for lung counting of transuranics (ANSI86). This value is 

acceptable since it represents the current state of the art. For the reported L 

X-ray yield of Pu-239 of 4.2% (ICRP83), this corresponds to an acceptable 

minimum detectable activity of 4.4 kBq (120 nCi). Based upon approximately 0.15 

of an intake of Class Wand Class Y compounds expected to be present in the 

lungs at 7 days, this corresponds to a minimum detectable intake of 2.9 E+04 Bq 

(790 nCi). The Class W and Class Y ALls for Pu-239 are respectively 200 Bq (5.4 

nCi) and 500 Bq (14 nCi). Thus, the minimum detectable intake corresponds to 

150 ALI for Class Wand 56 ALI for Class Y compounds of Pu-239 and committed 

doses to bone surfaces of 73 Sv (7,300 rem) and 28 Sv (2,800 rem) respectively. Although lung counting may be useful for very large accidental 

exposures to Pu-239, it should not be relied upon as the primary routine 

bioassay procedure. Other internal dose assessment procedures, such as fecal 

monitoring, attocuric-Ievel urine monitoring (M086), or the use of personal 

breathing zone air samplers (Sk85) should be used for assuring adequate 

protection from exposures involving Pu-239. « 

Urinary monitoring for Pu-239 may be a good choice if sufficient sensitivity is 

available. Recent advances in radiochemical separation of Pu in urine, in the 

presence of uranium, have resulted in a technique which has a minimum detectable 

activity (MDA) of 90 attocuries per liter for a one day urine sample (see ANSI86 

for the MDA equations for bioassay). The new system relies on a fluence of 

neutrons and the fissioning of Pu. However, even with attocurie sensitivity for 

Pu-239 for urine, the estimate of intake relies on associating the activity in 

urine with 1.0E-04 to 1.0E-07 of the activity inhaled or ingested. Thus, 

several urinary measurements are needed in order to reduce the order-ofmagnitude uncertainty associated with variation in Pu excretion due to diet. On 

the other hand, recent work by Jones on a urinary excretion function for Pu 

shows realistic estimates of uptake are obtained from sets of urinary 

measurements when judged against autopsy data (J085). Better agreement of the 

estimate of uptake from urinary results with autopsy results will occur if new 

values for retention of Pu in bone and liver are adopted by ICRP (ICRP85). 

Thus, urinary monitoring of Pu-239 is very appropriate, prOVided sufficient 

sensitivity is available. Because the annual limit of intake is based on the 

radiotoxic effects to bone, urinary monitoring may be more appropriate than 

feces monitoring, which may be associated mainly with the lung and gastrointestinal deposit of Pu-239. 

5.3 Table of Derived Investigation Levels 

To demonstrate how intake retention fractions can be used for the design and 

conduct of a bioassay program, derived investigation levels (DILs) have been 

calculated for some in-vivo or in-vitro compartments of interest. The levels 

were determined based upon the ICRP Publication 26 recommendation of 0.3 x f x 

ALI, where f is the fraction of the year to which the routine monitoring applies, and ALI is the annual limit on intake from ICRP Publication 30. Values 

for inhalation and ingestion intake of tritiated water, Co-60, 1-131, Cs-137, 

Sr-90, U-238, Pu-239 and Am-241 are summarized in Table 5.3.1. 

27 
Tahle 5.3.1 Derived Investigation Levels for An Acute Intake 

Time IRF In Compartment DIL In Compartment, Bq 

Post 

Intake, Total 24-Hour 

days Lungs Body Urine Lungs Body Urine 

Tritiated Water, Ingestion or Inhalation, ALI - 2.55 E+09 Bq 

1.0 9. 32E-01 3. 92E-02 1.95E+06 8. 22E+04 

5.0 7.05E-01 2. 96E-02 7.39E+06 3.lOE+05 

10.0 4.97E-01 2.09E-02 1.04E+07 4.38E+05 

30.0 1. 22E-01 5. 14E-03 7.67E+06 3. 23E+05 

100.0 9. 12E-04 3. 83E-05 1.91E+05 8.03E+03 

200.0 8. 32E-07 3. 49E-08 3.49E+02 1. 46E+01 

365.0 

Co-60, Ingestion, ALI = 2.02E+07 Bq 

1.0 7.06E-01 1. 25E-02 1. 17E+04 2.08E+02 

5.0 3. 54E-02 8. 48E-04 2. 94E+03 7.04E+01 

10.0 1.43E-02 4. 52E-04 2.37E+03 7.50E+01 

30.0 8.80E-03 7.21E-05 4.38E+03 3.59E+01 

100.0 5. 95E-03 1. 51E-05 9. 88E+03 2.51E+01 

200.0 4. 38E-03 6. 14E-06 1. 45E+04 2.04E+ 

365.0 3.28E-03 2. 57E-06 1. 99E+04 1.56E+0 

Co-60, Class W Inhalation, ALl = 5.43E+06 Bq 

1.0 2. 11E-01 5. 66E-01 2.59E-02 9. 42E+02 2. 53E+03 1. 16E+02 

5.0 1. 44E-01 2.06E-01 2. 26E-03 3.21E+03 4.60E+03 5.04E+01 

10.0 1.32E-01 1.63E-01 1.27E-03 5. 89E+03 7.27E+03 5. 67E+01 

30.0 1.01E-01 1.23E-01 4. 48E-04 1. 35E+04 1. 65E+04 6.00E+01 

100.0 4.03E-02 5. 77E-02 1.85E-04 1.80E+04 2.58E+04 8. 26E+01 

200.0 1.07E-02 2. 44E-02 6. 86E-05 9. 55E+03 2. 18E+04 6. 12E+01 

365.0 1.47E-03 1. 16E-02 1.77E-05 2.39E+03 1.89E+04 2.88E+01 

Co-60 • Class Y Iobalation, ALI - 8.47E+05 Bq 

. . 

1.0 2. 13E-01 5.83E-01 4.64E-03 1. 48E+02 4.06E+02 3. 23E+00 

5.0 1.52E-01 1.90E-01 8. 17E-04 5.29E+02 6.61E+02 2. 84E+00 

10.0 1.48E-01 1.57E-01 3. 33E-04 1.03E+03 1.09E+03 2. 32E+00 

30.0 1.43E-01 1.49E-01 6. 43E-05 2.99E+03 3.11E+03 1.34E+00 

100.0 1.30E-01 1.34E-01 2.60E-05 9.05E+03 9. 33E+03 1.81E+00 

200.0 1. 13E-01 1.llE-01 1.99E-05 1.57E+04 1. 63E+04 2. 77E+OO 

365.0 9.08E-02 9.37E-02 1. 64E-05 2.31E+04 2. 38E+04 4. 17E+00 

28 
Table 5.3.1 continued 

Time IRF In Compartment DIL In Compartment, Bq 

Post 

Intake, Total 24-Hour Total 24-Hour 

days Lungs Body Urine Lungs Body Urine 

Sr-90, Ingestion, ALI = 1.OOE+06 Bq 

1.0 7.1SE-01 S.8SE-02 S.88E+02 4. 81E+01 

S.O 1.S8E-01 1.30E-02 6.49E+02 S.34E+01 

10.0 9.90E-O'2 S.60E-03 8. 14E+02 4.60E+01 

30.0 6.04E-02 3. 41E-04 1.49E+03 8.41E+00 

100.0 S.11E-02 7.1SE-OS 4.20E+03 S.88E+00 

200.0 4.44E-02 4.21E-OS 7.30E+03 6.92E+00 

36S.0 3.80E-02 2. 37E-OS 1. 14E+04 7.11E+00 

Sr-90, Class D Inhalation, ALI = 7.008+05 Bq 

1.0 7.97E-02 S.OSE-01 8. S7E-02 4. S9E+01 2.91E+02 4. 93E+01 

S.O S.80E-04 2. 67E-01 2.4SE-02 1. 67E+00 7. 68E+02 7.0SE+01 

10.0 8.96E-07 1.78E-0l 1.04E-02 S.16E-03 1.02E+03 S.98E+01 

30.0 0.00 1.06E-01 6. 21E-04 0.00 1.83E+03 1.07E+01 

100.0 8.99E-02 1.26E-04 S.17E+03 7.2SE+OO 

200.0 7.81E-02 7.42E-OS 8.99E+03 8.S4E+00 

36S.0 6.68E-02 4.18E-OS 1.40E+04 8.78E+00 

Sr-90, Class Y Inhalation, ALI .. 1.00E+05 Bq 

1.0 2. 13E-01 S.86E-01 1.34E-03 1.7SE+01 4. 81E+0l lolOE-Ol 

S.O 1.S3E-01 1.8SE-01 4. 22E-04 6.29E+01 7.60E+01 1.73E-01 

10.0 1. 48E-0l 1.S2E-01 1.87E-04 1.22E+02 1.2SE+02 1. S4E-01 

30.0 1.4SE-0l 1.47E-01 2. 32E-OS 3. S8E+02 3.62E+02 S.72E-02 

100.0 1.34E-01 1.36E-01 1. SSE-OS 1.lOE+03 1. 12E+03 1.28E-01 

200.0 1.20E-01 1. 22E-01 1. SOE-OS 1.97E+03 2.01E+03 2.47E-01 

36S.0 1.00E-0l 1.03E-0l 1.47E-OS 3.00E+03 3.09E+03 4.41E-01 

I-l3I, Class D Inhalation, ALI = 1.858+06 Bq 

1.0 1.33E-01 2.74E-01 3.04E-01 2.02E+02 4.17E+02 4.62E+02 :'~"'w' S.O 1.20E-01 1.2SE-01 1. 31E-03 9. 12E+02 9.S0E+02 9. 96E+00 

10.0 7.S1E-02 8.00E-02 1.88E-04 1. 14E+03 1.22E+03 2.86E+00 

30.0 1.l6E-02 1. 32E-02 6.2SE-OS S.29E+02 6.02E+02 2.8SE+00 

100.0 1.80E-OS 2. lIE-OS 1. 24E-07 2.74E+00 3.21E+00 1.89E-02 

200.0 

36S.0 

29 
Table 5.3.1 continued 

Time IRF In Compartment DIL In Compartment, Bq 

Post 

Intake, Total 24-Hour Total 

days Lungs Body Urine Lungs Body 

I-131~ Ingestion, ALI = 1.33E+06 Bq 

1.0 2.S4E-01 3.21E-01 6. 43E-01 2.78E+02 3.S1E+02 7.03E+02 

S.O 1.88E-0l 1.94E-Ol 1.49E-03 1.03E+03 1.06E+03 8. 14E+00 

10.0 1.17E-0l 1.2SE-Ol 8.76E-04 1.28E+03 1.37E+03 9.S8E+00 

30.0 1.82E-02 2.06E-02 1. 16E-04 S.97E+02 6.76E+02 3.80E+00 

100.0 2. 82E-OS 3. 29E-OS 1.66E-07 3.08E+OO 3.60E+00 1.81E-02 

200.0 

36S.0 

Cs-137 , Ingestion, ALI = 3.57E+06 Bq 

1.0 9.66E-Ol 2.70E-02 2. 83E+03 7. 92E+Ol 

S.O 8.90E-Ol 1.03E-02 1.31E+04 1. SIE+02 

10.0 8. 48E-Ol S.32E-03 2. 49E+04 1. S6E+02 

30.0 7.44E-Ol 3.76E-03 6.SSE+04 3.31E+02 

100.0 4.76E-01 2.41E-03 1.40E+OS 7.07E+02 

200.0 2. S2E-Ol 1.27E-03 1.48E+OS 7.4SE+02 

36S.0 9. 24E-02 4. 68E-04 9.90E+04 5.01E+02 

Cs-137~ Class D Inhalation, ALI = 5.60E+06 Bq 

1.0 7.97E-02 6. 22E-01 1.3SE-02 3.67E+02 2. 86E+03 6.21E+Ol 

S.O 5.80E-04 5.72E-01 7.16E-03 1.33E+Ol 1. 32E+04 1.65E+02 

10.0 8.96E-07 5.43E-Ol 3.51E-03 4. 12E-02 2.50E+04 1.61E+02 

30.0 O.OOE+OO 4.76E-01 2. 41E-03 O.OOE+OO 6. 57E+04 3. 33E+02 

100.0 3.0SE-0l 1.54E-03 1.40E+05 7.09E+02 

200.0 1.61E-0l 8. 16E-04 1. 48E+05 7.51E+02 

36S.0 S.93E-02 3.00E-04 9.96E+04 5.04E+02 

U-238, Class D Inhalation, ALI ... 5.01E+04 Bq 

1.0 7.97E-02 4.lOE-0l 1. 87E-0l 3. 28E+00 1. 69E+Ol 7.70E+00 

5.0 5. 81E-04 1.68E-Ol 1.31E-02 1.20E-Ol 3. 46E+Ol 2.70E+OO 

10.0 8.96E-07 1.21E-0l 7.26E-03 3.69E-04 4.98E+Ol 2.99E+00 

30.0 O.OOE+OO 5.06E-02 1.7lE-03 O.OOE+OO 6. 25E+OI 2.11E+OO 

100.0 1.47E-02 1.11E-04 6.05E+Ol 4.57E-Ol 

200.0 1. 15E-02 S.15E-06 9.47E+01 4. 24E-02 

365.0 1.11E-02 1.72E-06 1.67E+02 2.S9E-02 

30 
Table 5.3.1 continued 

Time IRF In Compartment DIL In Compartment» Bq 

Post 

Intake, Total 24-Hour Total 24-Hour 

days Lungs Body Urine Lungs Body Urine 

8-238, Class W Inha1ation, ALl = 2.52E-t()4 Bq 

1.0 2.llE-0l S.S7E-0l 4.l3E-02 4. 37E+00 1.lSE+Ol S. SSE-Ol 

S.O 1.4SE-01 2.03E-Ol 2. 69E-03 1.SOE+Ol 2.l0E+Ol 2.79E-Ol 

10.0 1. 32E-0l I.S9E-0l I.7SE-03 2. 73E+OI 3. 29E+OI 3.62E-Ol 

30.0 I.02E-OI 1.I7E-OI 7.2SE-04 6. 34E+OI 7.27E+OI 4.S2E-OI 

100.0 4. ISE-02 4.SIE-02 2.43E-04 S.66E+OI 9.96E+OI S.03E-OI 

200.0 I.lSE-02 I.S7E-02 7.49E-OS 4. 76E+Ol 6.S0E+OI 3.1OE-OI 

36S.0 1. 66E-03 S.14E-03 I.29E-OS I.2SE+Ol 3.S9E+Ol 9.7SE-02 

U-238, Class Y Inhalation, ALl = 1.51E+03 Bq 

1.0 2.13E-OI S.SSE-Ol 2.23E-03 2.64E-OI 7.26E-OI 2.77E-03 

S.O 1.S3E-OI I.S3E-OI I.3IE-04 9.49E-OI I.14E+00 S.13E-04 

10.0 I.4SE-Ol 1.SOE-0l 8.42E-OS 1. 84E+00 1.S6E+00 I.04E-03 

30.0 1.4SE-OI 1. 46E-Ol 3. 27E-OS S.40E+00 S.43E+00 1. 22E-03 

100.0 1.3SE-Ol 1.3SE-OI 1. S7E-OS 1.6SE+OI 1.6SE+Ol 2.32E-03 

200.0 1.22E-Ol 1.22E-01 1. SlE-OS 3.02E+OI 3.03E+Ol 4.49E-03 

36S.0 I.03E-OI I.04E-0l I.S2E-OS 4. 67E+OI 4.71E+OI 8.26E-03 

U-238, Ingestion, ALl = 7.33E+06 Bq 

1.0 7.0IE-OI 2.76E-OI 4. 22E+03 1. 66E+03 

5.0 3.37E-02 2. 89E-02 1.02E+03 S.71E+02 

10.0 1.23E-02 2.00E-04 7.4IE+02 I.20E+OI 

30.0 S.I4E-03 0.00 9. 29E+02 0.00 

100.0 I.SOE-03 9.04E+02 

200.0 I.ISE-03 I.42E+03 

36S.0 I.14E-03 2.SIE+03 

Pu-239, Class W Inhalation, ALl = 2.03E+02 Bq 

1.0' 2.IIE-0l S.96E-OI 2.S3E-04 3.52E-02 9.94E-02 4. 72E-OS , S.O I.4SE-OI 2.4SE-OI S.39E-OS I.2lE-OI 2.04E-Ol 4.S0E-OS 

10.0 1.32E-OI 2.09E-Ol 2.S4E-OS 2.20E-OI 3. 49E-OI 4.24E-OS 

30.0 1.02E-Ol I.86E-OI 1. 76E-OS S.llE-OI 9.3IE-OI S.SlE-OS 

100.0 4.1SE-02 I.42E-OI I.12E-OS 6.97E-Ol 2. 37E+OO I.S7E-04 

200.0.· I.ISE-02 I.2IE-OI 7.S9E-06 3.S4E-0l 4.04E+00 2. 63E-04 

36S.0 I.66E-03 I.I4E-OI 4. 96E-06 I.OIE-OI 6.94E+00 3.02E-04 

31 
'Table 5.3.1 continued 

Time IRF In Compartment DIL In Compart ment , 

Post 

Intake, Total 24-Hour Total 

days Lungs Body Urine Lungs Body 

Pu-239, Class Y Inhalation, ALI = 5.26E+02 Bq 

1.0 2. 13E-01 5.87E-01 1. 55E-05 9.21E-02 2.54E-01 6.70E-06 

5.0 1.53E-01 . 1.85E-01 2. 87E-06 3.31E-01 4.00E-01 6.20E-06 

10.0 1.48E-01 1.53E-01 1.29E-06 6.40E-01 6.61E-01 5. 58E-06 

30.0 1.45E-01 1.49E-01 8.81E-07 1. 88E+00 1. 93E+00 1.14E-05 

100.0 1.35E-01 1.41E-01 ' 6.99E-07 5. 84E+00 6.lOE+00 3.02E-05 

200.0 1.22E-01 1.29E-01 7.73E-07 1. 05E+01 1. 12E+01 6. 68E-05 

365.0 1. 03E-01 1. 14E-01 8.03E-07 1.63E+01 1.80E+01 1.27E-04 

Pu-239, Ingestion, ALI = 2.43E+05 Bq 

1.0 2.82E-01 3. 31E-07 5.63E+01 6.61E-05 

5.0 3. 14E-02 7.42E-08 3. 14E+01 7.41E-05 

10.0 2.20E-04 2.84E-08 4. 39E-01 5. 67E-05 

30.0 O.OOE+OO 1.57E-08 O.OOE+OO 9.41E-05 

100.0 

200.0 

365.0 

Am-243, Ingestion, ALI = 5.00E+04 Bq 

1.0 7.14E-01 2. 86E-01 2. 93E+01 1. 18E+01 

5.0 1.87E-02 3.06E-02 3. 84E+00 6. 29E+00 

10.0 5.74E-04 2. 13E-04 2. 36E-01 8.75E-02 

30.0 4.50E-04 O.OOE+OO 5.54E-01 O.OOE+OO 

100.0 4.49E-04 1.85E+00 

200.0 4.47E-04 3.67E+00 

365.0 4. 45E-04 6. 68E+00 

Aa-243, Class W Inbalation, ALI = 2.00E+02 Bq 

« 

" .... , . 1.0 2.11E-01 5.90E-01 4.21E-02 3.47E-02 9.70E-02 6. 92E-03 

" . ! ' 5.0 1.45E-01 2. 39E-01 3.41E-02 1.19E-01 1.96E-01 2.80E-02 

10.0 1.32E-01 2.03E-01 2.07E-03 2.17E-01 3.34E-01 3.40E-03 

30.0 1.02E-01 1.80E-01 9.44E-04 5.03E-01 8. 88E-01 4. 66E-03 

100.0 4. 18E-02 1. 36E-01 3.58E-04 6.87E-01 2.24E+00 5. 88E-03 

200.0 1. 15E-02 1. 15E-01 8. 94E-05 3.78E-01 3.78E+00 2. 94E-03 

, 365.0 1.66E-03 1.09E-01 1. 15E-0,5 9.96E-02 6. 54E+00 6.90E-04 

32 
6. GENERAL EVALUATION 

6.1 Validation of Tabulated Results 

This section describes the methods used in the validation of tabular values, and 

presents results of selected validation tests. 

Validation was a process aimed at confirming that tabular data were correctly 

presented in Appendix B. However, the validation procedure does not verify or 

substantiate the correctness of model assumptions. Evidence which serves to 

verify the exactness of our methods is presented in Appendix A, Example of Use 

and Verification Based on Experiences. The validation study was performed by R. 

Belanger of Science Applications International Corporation, San Diego, 

Calif ornia • 

Validation was performed by comparison of selected tabular results with those 

generated by other computer models uSing the same set of assumptions. The 

programs used in the validation processes were REMedy and DOSEDAY/ DOSEYR, both 

of which are proprietary programs. REMedy invokes an analytic solution 

algorithm to solve the ICRP Publication 30 retention functions in a manner 

similar to that used by the model which generated the tabular results in 

Appendix B. The DOSEDAY/DOSEYR program uses a Runge-Kutta integration routine 

to numerically solve the rate equations presented in ICRP Publication 30. 

A third computer program was used to evaluate the tables in Appendix B and the 

output was similar to REMedy. However, this third validation study was 

performed by J. R. Johnson of the Dosimetric Research Branch, Chalk River 

Nuclear Laboratory, Canada, and Dr. Johnson validated the tables corresponding 

to the stable elements. Since tables for radioisotopes differ from the table 

for the stable elements by the decay factor, it was felt that this third study 

was comprehensive. The errors discovered by this study were corrected. Since 

output of Dr. Johnson's study was similar (within a few %) to REMedy output, we 

felt specific details need not be reproduced here. 

6.1.1 General Description of the REMedy Model 

REMedy is a Pascal-language program which uses an analytic solution algorithm to 

predict the fraction of an intake present in a bioassay compartment at some time 

post-intake. The program is capable of calculating fraction of intake in the 

whole body, lung, 24-Hr urine, cumulative urine, 24-Hr feces, cumulative feces, 

and thyroid (for radioiodine) bioassay compartments as a result of ingestion or 

inhalation. Both acute and chronic intake modes are evaluated and corrections 

can be made for deposition as a function of particle size. 

The general form equation used in REMedy to solve retention function problems is 

" identical to that presented as equation (1) in Section 2.5 of this report. One 

notable change in the REMedy metabolic model from the BNL model, however, is 

that REMedy assumes the existence of a transfer compartment as discussed in ICRP 

Publication 30. For purposes of validation, the clearance halftime for the 

transfer compartment was set equal to the halftime-of the first exponential term 

of the BNL model for the respective radionuclides. As is discussed below, this 

fact may account for minor differences in calculations of retention for a few to 

several days post-intake. 

33 
. ~ .. 

The radionuclide library contents of REMedy was edited for this task to set 

all assumed values equal to those contained in the Element Data Sheets of 

Appendix B. For those cases in which the fractions of systemic excretion 

leaving the body via urine and feces are not defined (e.g., iron), the fraction assigned to urine excretion was unity. In this case, the urine retenti 

values calculated by REMedy can be compared to the systemic excretion values 

in the tables. 

6.1.2 General Description of DOSEDAY and DOSEYR 

DOSEDAY and DOSEYR are programs which numerically integrate the rate equations 

presented in ICRP Publication 30. The numerical i~tegration routine used is a 

simple Runge-Kutta method. Since the rate equations form a system of very 

stiff differential equations, special attention must be paid to step size. 

Step sizes are chosen on the basis of the fastest compartment clearance rate. 

Compartments which contain retention fractions of less than 1.0E-6 are assumed 

to equal zero, except in the cases of closely coupled flow, for example from 

lung compartments f to d to the GI tract, or the case of a positive derivative. A material balance is maintained for activity present in all compartments, activity lost by radiodecay, and all losses assumed equal to zero. 

DOSEDAY integrates on a time scale of days. Once all lung and GI compartment 

retention values reach zero, the integration is passed to the DOSEYR routine, 

which integrates on a time scale of years. Results may be printed from either 

routine for fractions or multiples of days or years. 

Deposition fractions, removal rate constants and compartmental fractions 

assumed for the inhalation model may be changed from those specified by Figure 

5.2 of ICRP Publication 30 as keyboard input. While not clearly specified 

ICRP Publication 30, for cases where fl is equal to unity, all contents of t 

stomach are assumed to be absorbed at 1

a rate equal to the translocation rate 

of stomach contents, which is 24 day- • 

6.1.3 Input Values for Validation Tests 

The DOSEDAY/DOSEYR routines use the compartment transfer rate constants for 

each radioelement given in lCRP Publication 30, as opposed to retention 

functions. Where differences in rate constants for males and females are 

specified, for example~ for Pu and Am, the values for Reference Male were 

used. The lung deposition fractions and excretion pathway fractions used were 

the same as those specified in the Element Data Sheets of Appendix B. Where 

systemic excretion pathway fractions were listed as not defined, it was 

assumed that the fraction of systemic excretion going to urine was unity • 

The physical halflives used for the radionuclides were obtained from the 

Radiological Health Handbook (USDHEW70), and are as follows: 

Nuclide 

~-w 

1-131 

U-235 

Pu-239 

Am-241 

Halflife(Year) 

5.26 E+OO 

2.21 E-02 

7.10 E+08 

2.40 E+04 

4.58 E+02 

34 

Halflife(Day) 

1.92 E+03 

8.05 E+OO 

2.59 E+ll 

8.78 E+06 

1.67 E+05 
Excretion compartment values are cumulative from the time of intake, so hand 

calculations were necessary to estimate 24-hour incremental urine and fecal 

values. The excretion compartment retention was obtained using the following 

formula: 

where: 

24-Hr Total = (B - A) x EXP (-lambda x T) 

B is the stable element cumulative fraction at time T days post 

intake, 

A is the stable element cumulative fraction at time T - 1 days 

post intake, and 

lambda is the radiodecay constant, day-I. 

This equation corrects the value calculated at 24 hours for any activity 

present at the start of the 24-hour period. 

6.1.4 Validation Results 

The results of the validation tests are presented in Tables 6.1.1 through 

6.1.4. All results generated by REMedy or DOSEDAYjDOSEYR have been rounded to 

two decimal places. Wherever dashes appear in the tables, no results are 

available. Values presented as O.OOE+OO represented values less than 1.0E-6 

for DOSEDAY/DOSEYR results, and values less than approximately 1.0E-I0 for 

REMedy results. 

Table 6.1.1 presents the results of validation runs for excreta retention 

following inhalation of particles of 1 micrometer AMAD. For these cases, the 

deposition values in REMedy and DOSEDAY/DOSEYR have been set to 0.31 for nasal 

passages, 0.08 for the trachea and bronchial tree, and 0.249 for the pulmonary 

region. The results of this test can be summarized as follows: 

1. For Class D compounds, there is good agreement for Sr-90, 1-131, and u235. There are relatively minor «11%) urine and fecal retention discrepancies 

for Fe-59 and Cs-137 up to 10 days post-intake, and for Fe-59 cumulative feces 

at 500 days. 

2. For Class W compounds, there is very good agreement for Co-60, Th-232, 

and U-235. There are discrepancies «11%) in the case of Fe-59, Ce-144, and 

Pu-239 for urine retention at 1 day. There are also minor discrepancies «3%) 

for fecal retention for Fe-59 beyond 100 days and Co-60 at 5 days. 

3. For Class Y compounds, there is very good agreement for all four nuclides 

tested. There are minor discrepancies «10%) in each case, but these 

differences may be explained by the difference in use of the transfer 

compartment. 

Validation results of whole body and lung retention following inhalation are 

presented in Table 6.1.2. There is very close agreement between BNL and 

REMedy results for all cases of Class D, Class W and Class Y nuclides except 

for minor discrepancies «5%) between the 1-131 results of BNL and REMedy 

compared to those predicted by DOSEDAY. 

Table 6.1.3 presents validation test results .for ingestion. Except for 

35 
isolated cases, there is very close agreement between the BNL and REMedy 

results. The DOSEDAY/DOSEYR routines were not used in the ingestion tests. 

Whole body retention results agreed very closely in all cases. Incremental 

urine retention of Am-241 (by 6%) varies between the models for times after 

days, and excreta retention for Cs-137 varies somewhat «11%) for the first 

few days post-intake, after which time close agreement is reached. 

Table 6.1.4 presents predicted thyroid retention following inhalation of 

Class D 1-131. There is a minor «6%) discrepancy between the BNL and REMedy 

results for day 1, although the BNL and DOSEDAY results for this time agree 

closely. There is very good agreement between results at day 5, and there are 

relatively minor «6%) variations thereafter. 

6.1.5 Conclusions Drawn from Validation Studies 

Several meaningful conclusions can be drawn from the results of the validation 

tests. It can be concluded that for almost all cases of in vivo retention, 

the tabular results appear to accurately represent a retention value expected 

on the basis of ICRP Publication 30 metabolic models. It is difficult to explain the apparent discrepancies in some cases of expected excreta retention. 

These discrepancies are attributed to slightly different interpretations of 

the metabolic models presented in ICRP Publication 30. In particular, two 

distinct variations of ICRP models are employed in the algorithms contained in 

the programs used in the validation tests. The algorithms used in the REMedy 

and DOSEDAY/DOSEYR codes include a single catenary transfer compartment as a 

component of the metabolic model. An example of a lung-to-excretion pathway 

for such a model would be: Lung Compartment "a" -) Transfer Compartment -) 

Systemic Compartment -) Excretion. An alternative approach is employed in the 

model described in Section 2 of this report. This approach neglects the 

existence of the Transfer Compartment, so the corresponding pathway would 

described by: Lung Compartment "a" -) Systemic Compartment - )Excretion. 

Since the Transfer Compartment is assumed to have a relatively short clearance 

half-time, 0.25 to 0.5 days, systemic retention and excretion resultscalculated using these alternative approaches can differ significantly for times up 

to several days post-intake. Little difference would usually be exhibited 

beyond this time. The use of alternative models is believed to account for 

many of the discrepancies mentioned above. 

36 
Table 6.1.1 Validation of Inhalation Results for Excreta Heasurements 

CLASS D 

24-HOUR URINE ACCUMULATED URINE 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Fe-59(D) 1 1.16E-04 7.25E-05 1.16E-04 7.25E-05 

fu=l 5 1.58E-04 1.58E-04 7.23E-04 6.67E-04 

10 1. 47E-04 1.47E-04 1.40E-03 1. 35E-03 

50 7.76E-05 7.90E-05 3. 88E-03 3. 92E-03 

100 3.5UE-05 3. 63E-05 3.55E-03 3.66E-03 

500 6.03E-08 7.23E-08 3. 29E-05 3.94E-05 

Sr-90(D) 1 8.57E-02 8.04E-02 8.57E-02 8.04E-02 

fu=0.85 5 2.45E-02 2.60E-02 2.23E-Ol 2. 19E-0l 

10 1.04E-02 1.11E-02 2.97E-Ol 2.98E-0l 

50 1.94E-04 1.89E-04 3.63E-01 3.63E-Ol 

100 1.26E-04 1.26E-04 3.83E-0l 3. 83E-0l 

500 2.86E-05 2. 93E-05 3.83E-Ol 3.83E-Ol ---

I-131(D) 1 3.13E-01 3.13E-01 3.13E-Ol 3. 13E-Ol 3.08E-0l 

fu=l 5 1.35E-03 1.34E-03 2.91E-01 2. 91E-Ol 2.87E-Ol 

10 1. 93E-04 1. 88E-04 1.90E-01 1.91E-01 1. 87E-0l 

50 1.20E-05 1.21E-05 6.47E-03 6.50E-03 6. 87E-03 

100 1.27E-07 1.29E-07 9.41E-05 9.50E-05 

500 

Cs-137(D) 1 1. 35E-02 8.74E-03 1.35E-02 8.74E-03 

fu=0.8 5 7.16E-03 7. 75E-03 5.38E-02 5. 13E-02 

10 3.51E-03 3.63E-03 7.63E-02 7.51E-02 

50 2.12E-03 2. 13E-03 1.74E-01 1. BE-01 

100 1.54E-03 1.55E-03 2.64E-0l 2.63E-01 

500 1.21E-04 1.21E-04 4.76E-01 4.76E-01 

U-235(D) 1 1.87E-01 1.93E-Ol 1.93E-01 1.87E-01 1.93E-Ol 1.93E-Ol 

fu""l 5 1.31E-02 1.32E-02 1.32E-02 3.23E-01 3. 19E-Ol 3. 19E-Ol 

10 7.26E-03 7.49E-03 7.50E-03 3.67E-0l 3.65E-Ol 3.65E-Ol 

50 6. 67E-04 6.77E-04 4.59E-Ol 4.60E-Ol 

100 1.11E-04 1. 13E-04 4.73E-Ol 4.74E-0l 

500 1.64E-06 1.63E-06 4. 77E-Ol 4.78E-Ol 

37 
Table 6.1.1 (continued) 

CLASS D 

24-HOUR FECES ACCUMULATED FEC 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Fe-S9(D) 1 4.0IE-02 3.9SE-02 4.0IE-02 3.9SE-02 

fu=I S 4.0BE-03 4. 18E-03 1. 30E-OI I.30E-OI 

10 2.62E-OS 2.7iE-OS I.22E-OI I.23E-OI 

SO O.OOE+OO O.OOE+OO 6. S7E-02 6.69E-02 

100 O.OOE+OO O.OOE+OO 3.02E-02 3.13E-02 

500 O.OOE+OO O.OOE+OO 5.96E-OS 7.16E-OS 

Sr-90(D) 1 4.8SE-02 4.71E-02 4.8SE-02 4.7IE-02 

fu=O.BS 5 7. 62E-03 7. 97E-03 1. 49E-OI I.48E-OI 

10 1. BSE-03 I.97E-03 I.64E-OI I.64E-OI 

SO 3. 42E-OS 3.33E-OS 1. 75E-OI I.7SE-OI 

IUO 2. 22E-05 2.23E-05 I.76E-0l I.76E-OI 

500 5.04E-06 5.17E-06 I.7SE-OI I.7SE-OI 

I-13I(D) 1 S.IBE-08 5.IBE-OB 

fu-I 5 4.B6E-OB I.02E-07 

10 O.OOE+OO 6.17E-OB 

50 O.OOE+OO 2.13E-09 

100 O.OOE+OO 

500 

Cs-I37 (D) 1 3.37E-03 2.IBE-03 3.37E-03 2.20E-03 

fu=0.8 S 1. 79E-03 1. 94E-03 I.3SE-02 1. 28E-02 

10 B.77E-04 9.07E-04 I.9IE-02 I.B8E-02 

50 S.30E-04 5.3IE-04 4.35E-02 4.33E-02 

100 3.B6E-04 3. B6E-04 6.60E-02 6.59E-02 

500 3.03E-05 3.03E-OS I.I9E-OI I.I9E-OI 

U-235(D) 1 4. 24E-02 4.IBE-02 4.IBE-02 4.24E-02 4.IBE-02 4.IBE-02 

fu=I S 4.70E-03 4.BIE-03 4. BOE-03 I.4BE-OI 1.48E-OI I.4BE-OI 

10 3.26E-05 3.37E-05 4.00E-04 1. SIE-OI 1. SIE-OI 1. SIE-OI 

50 O.OOE+OO O.OOE+OO 1. SIE-Ol 1.SIE-OI I.5IE-Ol 

100 O.OOE+OO O.OOE+OO I.SIE-Ol 1. SlE-Ol I.5IE-OI 

500 O.OOE+OO O.OOE+OO I.SIE-OI 1. SIE-OI I.5IE-Ol 

.. 

'" . " 

3B 
Table 6.1.1 (continued) 

CLASS W 

24-HOUR URINE ACCUMULATED URINE 

NUCLIDE DAY BNL REMedy DOSE DAY BNL REMedy DOSEDAY 

(CLASS) 

Fe-59(W) 1 2.87E-05 1. 82E-05 2. 87E-05 1. 82E-05 

fu=1 5 3.68E-05 3. 67E-05 1. 69E-04 1. 57E-04 

10 3.51E-05 3.52E-05 3.30E-04 3. 19E-04 

50 2. 17E-05 2.20E-05 9. 93E-04 1.00E-03 

100 1.09E-05 1. 13E-05 9.79E-04 1.01E-03 

500 2. 12E-08 2. 54E-08 1.08E-05 1. 29E-05 

Co-60(W) 1 2. 27E-02 2. 17E-02 2. 16E-02 2.27E-02 2. 17E-02 2. 16E-02 

fu=0.7 5 1.98E-03 2.08E-03 2.06E-03 4. 14E-02 4.03E-02 4.03E-02 

10 1.IIE-03 1. 18E-03 4.81E-02 4.74E-02 4.74E-02 

50 2. 72E-04 2.73E-04 6. 59E-02 6.58E-02 6. 57E-02 

100 1.62E-04 1. 63E-04 7.51E-02 7.50E-02 7.50E-02 

500 6.69E-06 6.70E-06 7.99E-02 7.99E-02 7. 98E-02 

Ce-144(W) 1 1. 39E-05 9. 12E-06 1.39E-05 9. 12E-06 

fu=1 5 1. 43E-05 1. 43E-05 7.05E-05 6. 54E-05 

10 1.46E-05 1.46E-06 1.42E-04 1.37E-04 

50 1.59E-05 1. 59E.,.05 7.17E-04 7.12E-04 

100 1.59E-05 1.59E-05 1.39E-03 1.38E-03 

500 3.13E-03 3. 12E-03 

Th-232(W) 1 5.33E-03 5. 32E-03 5.33E-03 5.32E-03 

fu=1 5 9.04E-05 9.02E-05 7.41E-03 7.40E-03 

10 6.72E-05 6.71E-05 7.76E-03 7.74E-03 

50 5. 52E-05 5.51E-05 1.02E-02 1.02E-02 

100 4.44E-05 4.43E-05 1. 27E-02 1.26E-02 

500 2. 24E-05 2. 24E-05 2.43E-02 2. 42E-02 

U-235(W) 1 4. 13E-02 4.24E-02 4. 24E-02 4. 13E-02 4.24E-02 4. 24E-02 

fu=1 5 2.69E-03 2.73E-03 2. 73E-03 6. 28E-02 6.20E-02 6.20E-02 

10 1.75E-03 1.79E-03 1.78E-03 7.30E-02 7.25E-02 7.25E-02 

50 4.80E-04 4. 82E-04 1.06E-Ol 1.06E-Ol 1.06E-Ol 

100 2.43E-04 2.43E-04 1.23E-Ol 1.23E-Ol 1. 23E-Ol 

500 2. 46E-06 2.46E-06 1.43E-Ol 1.43E-Ol 1.43E-Ol 

Pu-239(W) 1 2. 83E-04 1.97E-04 2.83E-04 1.97E-04 

fu=0.54 5 5.39E-05 6. 14E-05 7.01E-04 6. 86E-04 

10 2.54E-05 2.60E-05 8.59E-04 8.54E-04 

50 1.45E-05 1.46E-05 1.58E-03 1.58E-03 

100 1. 12E-05 1.12E-05 2.21E-03 2.21E-03 

500 3. 59E-06 3.60E-06 4.73E-03 4.71E-03 
Table 6.1.1 (continued) 

CLASS W 

24-HOUR FECES ACCUMULATED FECES 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy 

(CLASS) 

Fe-S9(W) 1 3.87E-02 3.87E-02 3.80E-02 

fu=l S 2.8lE-02 3.27E-01 3. 27E-01 

10 1. S8E-03 3.30E-01 3.13E-01 

SO 2.96E-04 1.93E-01 1.97E-01 

100 6.79E-OS 9.3SE-02 9.70E-02 

SOO O.OOE+OO 1. 94E-04 2. 33E-04 

Co-60(W) 1 S.04E-02 4.93E-02 4.94E-02 S.04E-02 4.93E-02 4.94E-02 

fu=0.7 S 3.03E-03 3.3SE-02 3. 33E-02 3.90E-01 3. 89E-Ol 3. 89E-Ol 

10 2. 43E-03 2.47E-03 4.26E-Ol 4.26E-01 4.26E-01 

SO 7.84E-04 7.8SE-04 4.64E-01 4.64E-Ol 4. 64E-01 

100 3. 97E-04 3.98E-04 4.84E-Ol 4.83E-Ol 4.84E-01 

SOO 3.98E-06 3. 98E-06 4.4SE-01 4.4SE-Ol 4.4SE-01 

Ce-144(W) 1 4.20E-02 4.14E-02 4.20E-02 4.14E-02 

fu=l S 3. 37E-02 3. 42E-02 3. 88E-01 3. 87E-Ol 

10 2.02E-03 2.03E-03 4. 18E-0l 4.18E-0l 

SO 6. 33E-04 6.33E-04 4.13E-01 4.13E-01 

100 2.80E-04 2.80E-04 3.86E-01 3. 86E-Ol 

sao 4.13E-07 4.12E-07 1. S3E-01 1.S3E-01 

Th-232(W) 1 4. 22E-02 4.1SE-02 4.22E-02 4.1SE-02 

fu=l S 3. 42E-02 3. 46E-02 3.93E-Ol 3. 92E-Ol 

10 2.07E-03 2.08E-03 4.28E-0l 4.28E-01 

so 7.16E-04 7.1SE-04 4.67E-Ol 4.67E-Ol 

100 3. S8E-04 3. SBE-04 4.93E-01 4.92E-Ol 

SOO 1. 62E-06 1.40E-06 S.lBE-Ol S.lBE-Ol 

U-23S(W) 1 4.07E-02 4.01E-02 4.OlE-02 4.07E-02 4. 01E-02 4.01E-02 

fu=l S 3. 23E-02 3. 27E-02 3. 27E-03 3. 13E-Ol 3.73E-01 3.13E-01 

10 1.97E-03 1.97E-03 2.00E-03 4.07E-0l 4.07E-01 4.07E-01 

SO 6.80E-04 6. BOE-04 4.44E-01 4.44E-Ol 4.44E-01 

100 3.40E-04 3.40E-04 4.68E-Ol 4.68E-Ol 4.69E-01 

SOO 1.33E-06 1.33E-06 4. 92E-01 4. 92E-01 4. 93E-01 

Pu-239(W) 1 4.24E-02 4. 16E-02 4.24E-02 4. 16E-02 

fu=O. S4 S 3. 42E-02 3. 46E-02 3. 93E-01 3. 93E-01 

10 2.09E-03 2.l0E-02 4. 29E-01 4.29E-Ol 

So 7.2BE-04 7.2BE-04 4. 68E-01 4.6BE-01 

100 3. 67E-04 3.67E-04 4.94E-01 4. 94E-01 

SOO 4.46E-06 4.47E-06 S.22E-Ol S.22E-01 

40 
Table 6.1.1 (continued) 

CLASS Y 

24-HOUR URINE ACCUMULATED URINE 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Co-60(Y) 1 4. 64E-03 3. 87E-03 4. 63E-03 3.90E-03 

fu=O.7 5 8. 17E-04 7.41E-04 1.38E-02 1. 17E-02 

lO 3.33E-04 3. 14E-04 1.60E"':'02 1.38E-02 

50 3.52E-05 3. 19E-05 1.95E-02 1.70E-02 

100 2.60E-05 2.43E-05 2.06E-02 1.81E-02 

500 1. 48E-05 1. 64E-05 2. 45E-02 2. 26E-02 

Th-232(Y) 1 2. 95E-04 2.95E-04 2.95E-04 2.95E-04 

fu=l 5 4. 22E-06 4. 22E-06 4. 12E-04 4. 11E-04 

lO 2.81E-06 2.84E-06 4. 26E-04 4.26E-04 

50 2.98E-06 3. 13E-06 5. 42E-04 5. 45E-04 

100 3. 19E-06 3. 49E-06 6.97E-04 7.11E-04 

500 4.51E-06 5. 67E-06 2. 26E-03 2. 59E-03 

U-235(Y) 1 2.23E-03 2.29E-03 2.23E-03 2.29E-03 

fu=l 5 1.31E-04 1.34E-04 . 3.30E-03 3. 26E-03 

lO 8. 42E-05 8.66E-05 3.79E-03 3.77E-03 

50 2. 34E-05 2.47E-05 5. 32E-03 5.34E-03 

100 1.87E-05 2.l1E-05 6. 33E-03 6.45E-03 

500 1.81E-05 2. 44E-05 1. 36E-02 1. 58E-02 

Pu-239(Y) 1 1. SSE-OS 1.08E-05 1. SSE-OS 1.08E-05 

fu=0.54 5 2.87E-06 3.28E-06 3. 82E-05 3.74E-05 

lO 1. 29E-06 1.33E-06 4.63E-05 4. 61E-05 

50 7. 57E-07 7. 79E-07 8. 27E-05 8. 32E-05 

100 6.99E-07 7.47E-07 1. 18E-04 1.21E-04 

500 8.45E-07 1.07E-06 4.29E-04 4. 94E-04 

41 
~ble 6.1.1 (continued) 

CLASS Y 

24-HOUR FECES ACCUMULATED 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Co-60(Y) 1 S.lSE-02 S.l1E-02 S.lSE-02 S.11E-02 

fu-0. 7 S 3.4SE-02 3.S1E-02 4. 34E-Ol 4.3SE-Ol 

10 1.01E-03 1.08E-03 4.64E-Ol 4.66E-Ol 

SO 1. 29E-04 1.34E-04 4. 64E-ol 4. 66E-Ol 

100 1.17E-04 1.21E-04 4. 62E-Ol 4.64E-0l 

SOO S.87E-OS 6.20E-OS 4.31E-Ol 4. 34E-Ol 

Th-232(Y) 1 S.21E-02 S.12E-02 S.21E-02 S.12E-02 

fu-l S 3. 64E-02 3. 69E-02 4.SlE-01 4.S3E-Ol 

10 9.8SE-04 1.00E-03 4.86E-Ol 4.86E-0l 

SO 1. 29E-04 1.29E-04 4.92E-Ol 4.92E-Ol 

100 1.21E-04 1.21E-04 4.98E-Ol 4.98E-Ol 

SOO 6.94E-OS 6. 93E-OS S.3SE-Ol S.35E-Ol 

U-23S(Y) 1 S.20E-02 S.12E-02 S.20E-02 S.12E-02 

fu-l S 3.63E-02 3. 68E-02 4.53E-Ol 4. 52E-Ol 

10 9. 83E-04 9.98E-04 4.85E-01 4.85E-0l 

50 1. 29E-04 1.29E-04 4.9lE-01 4.91E-01 

100 1.20E-04 1.20E-04 4.97E-Ol 4.97E-01 

500 6. 92E-05 6.91E-05 S.34E-01 5. 34E-Ol 

Pu-239(Y) 1 5.21E-02 S.12E-02 5.21E-02 S.12E-02 

fu-0.54 5 3. 64E-02 3. 69E-02 4.54E-Ol 4.53E-Ol 

10 9. 87E-04 1.00E-03 4. 86E-Ol 4. 86E-0l 

50 1.30E-04 1.30E-04 4. 92E-Ol 4. 92E-Ol 

100 1.21E-04 1.2lE-04 4.98E-0l 4.98E-0l 

500 7.00E-OS 7.02E-05 5.36E-Ol 5. 36E-Ol 

42 
Table 6.1.2 Validation of Inhalation Results for In Vivo Heaaurements 

CLASS D 

WHOLE BODY LUNGS 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Fe-59(D) 1 5. 89E-01 5.90E-01 7.85E-02 7.84E-02 

5 4.61E-0l 4. 61E-01 5.37E-04 S.37E-04 

10 4. 23E-01 4.2SE-01 7.67E-07 7.68E-07 

50 2. 24E-01 2. 28E-01 O.OOE+OO O.OOE+OO 

100 1.01E-0l 1.05E-0l O.OOE+OO O.OOE+oo 

SOO 1.74E-04 2.09E-04 O.OOE+OO O.OOE+OO 

Sr-90(D) 1 S.OSE-01 5.llE-01 7.97E-02 7.96E-02 

S 2. 67E-01 2. 12E-01 5.80E-04 6.00E-04 

10 1.78E-0l 1.76E-01 8.96E-07 8. S7E-07 

SO 9. 91E-02 9.90E-02 O.OOE+OO O.OOE+OO 

100 8.99E-02 8.98E-02 O.OOE+OO O.OOE+OO 

500 6.07E-02 6.03E-02 O.OOE+OO O.OOE+OO 

1-131 (D) 1 2.74E-0l 2.74E-01 2.700-01 7.31E-02 7.31E-02 7.34E-02 

S 1.25E-01 1.2SE-01 1.23E-01 3.77E-04 3.77E-04 3. 73E-04 

10 8.00E-02 8.02E-02 7.94E-02 3.79E-07 3.78E-07 0.000+00 

SO 2.llE-03 2.1OE-03 2. 49E-03 O.OOE+OO O.OOE+OO O.OOE+OO 

100 O.OOE+OO 

500 

Cs-137(D) 1 6.22E-01 6.28E-01 7.97E-02 7.96E-02 

5 S.12E-01 5. 75E-01 5.80E-04 5.80E-04 

10 S.43E-01 5.4SE-01 8.96E-07 8.9SE-07 

SO 4. 19E-01 4.20E-01 O.OOE+OO O.OOE+OO 

100 3.0SE-01 3.06E-01 O.OOE+OO O.OOE+OO 

SOO 2. 39E-02 2.40E-02 O.OOE+OO O.OOE+OO 

U-235(D) 1 4.10E-0l 4.04E-01· 4.0SE-0l 7.97E-02 7.96E-02 7.99E-02 

5 1.69E-01 1.12E-01 1.12E-01 5.81E-04 5.80E-04 5.83E-04 

10 1. 21E-01 1. 23E-01 1.24E-01 8.96E-07 8.95E-07 O.OOE+OO 

50 2. 96E-01 2.98E-02 2. 93E-02 O.OOE+OO O.OOE+OO 

100 1.47E-02 1. 47E-02 1. 45E-02 O.OOE+OO O.OOE+oo 

500 1.09E-02 1.09E-02 1.09E-02 O.OOE+OO O.OOE+OO 

43 
Table 6.1.2 (continued) 

CLASS W 

WHOLE BODY LUNGS 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy 

(CLASS) 

Fe-59(W) 1 5.91E-01 5.91E-01 2.07E-01 2.07E-01 

5 2.64E-01 2. 65E-01 1. 34E-01 1.34E-01 

10 2. 17E-0l 2.1BE-0l 1.l3E-01 1.l3E-01 

50 9.95E-02 1.01E-01 3.64E-02 3.70E-02 

100 4.03E-02 4.1BE-02 B. B1E-03 9.l3E-03 

500 6.12E-05 7.35E-05 9. 62E-OB 1.15E-07 

Co-60(W) 1 5.66E-01 5.6BE-0l 5.6BE-01 2.llE-0l 2.10E-0l 2.llE-0l 

5 2.06E-01 2.0SE-01 2.0BE-01 1.44E-01 1.44E-01 1.44E-01 

10 1.63E-01 1.64E-Ol 1.64E-01 1.32E-01 1.32E-0l 1.32E-01 

50 9.7BE-02 9. 79E-02 9. 79E-02 7.7BE-02 7.7BE-02 7.7BE-02 

100 5.77E-02 5.7BE-02 5.7BE-02 4.03E-02 4.03E-02 4.03E-02 

500 B.49E-03 B.44E-03 B.49E-03 1.93E-04 1. 93E-04 1.93E-04 

Ce-144(W) 1 5.96E-01 5.96E-01 2.10E-0l 2.10E-0l 

5 2.44E-01 2.44E-01 1.43E-01 1.43E-01 

10 2.06E-01 2.06E-01 1.29E-01 1.29E-01 

50 1. 52E-01 1. 52E-01 7.02E-02 7.01E-02 

100 1.l3E-0l 1.l3E-Ol 3.27E-02 3.27E-02 

500 3.27E-02 3. 26E-02 6.B2E-05 6. BOE-05 

Th-232(W) 1 5.92E-01 5.92E-01 2.llE-0l 2.llE-0l 

5 2.39E-01 2.40E-01 1. 45E-01 1.44E-01 

10 2.03E-01 2.03E-01 1.32E-0l 1.32E-01 

50 1.62E-01 1. 62E-01 7.93E-02 7.92E-02 

100 1. 34E-01 1. 34E-01 4.1BE-02 4.1BE-02 

500 9.6BE-02 9. 68E-02 2.31E-04 2. 31E-04 

U-235(W) 1 5.57E-01 5.57E-01 5.57E-01 2.llE-0l 2.llE-0l 2.llE-01 

5 2.03E-01 2.04E-01 2.05E-01 1.45E-01 1.44E-01 1.45E-01 

10 1.59E-01 1.60E-01 1.60E-01 1.32E-01 1.32E-0l 1.33E-01 

50 8. 95E-02 B.95E-02 B.9BE-02 7.93E-02 7.92E-02 7. 95E-02 

100 4.81E-02 4. B1E-02 4. B3E-02 4.1BE-02 4.1BE-02 4. 19E-02 

500 3. 54E-03 3. 53E-03 3. 54E-03 2.31E-04 2.31E-04 2.31E-04 

.' Pu-239(W) 1 5.96E-01 5.97E-01 2.l1E-0l 2.l1E-0l 

5 2.45E-01 2.46E-01 1.45E-01 1.44E-01 

10 2.09E-01 2.09E-01 1.32E-01 1.32E-01 

50 1.69E-01 1.69E-01 7. 93E-02 7. 92E-02 

100 1.42E-0l 1.42E-01 4.1BE-02 4.1BE-02 

500 1.12E-01 1.12E-01 2.31E-04 2.31E-04 

44 
Table 6.1.2 (continued) 

CLASS Y 

WHOLE BODY LUNGS 

NUCLIDE DAY BNL REMedy DOSEDAY BNL REMedy DOSEDAY 

(CLASS) 

Am-241(W) 1 5.91E-01 5.92E-01 2.UE-01 2.UE-01 

5 2.40E-01 2.40E-01 1.44E-01 1.45E-01 

10 2.03E-01 2.04E-01 1.32E-01 1.33E-01 

50 1.63E-01 1. 63E-01 7. 92E-02 7. 95E-02 

100 1.36E-01 1.36E-0l 4. 17E-02 4. 19E-02 

500 1.08E-01 2.30E-04 

Co-60(Y) 1 5.B3E-01 5.84E-01 2.BE-01 2. 13E-0l 

5 1.90E-01 1.91E-01 1. 52E-01 1. 52E-01 

10 1.57E-01 1.57E-01 1.48E-0l 1. 47E-0l 

50 1.44E-01 1.44E-01 1.39E-01 1. 39E~01 

100 1.34E-01 1.34E-01 1.30E-01 1.30E-01 

500 7. 82E-02 7.65E-02 7.56E-02 7.37E-02 

Th-232(Y) 1 5. 87E-0l 5.B7E-01 2.BE-01 2.BE-01 

5 1. 85E-01 1. 85E-01 1. 53E-01 1.53E-01 

10 1. 53E-0l 1.53E-01 1.48E-0l 1.48E-01 

50 1. 47E-0l 1.46E-01 1. 42E-0l 1.42E-01 

100 1.40E-01 1.40E-01 1.35E-0l 1.35E-01 

500 1.02E-01 1.01E-01 9.06E-02 8. 82E-02 

U-235(Y) 1 5.85E-0l 5.86E-01 2. 13E-0l 2.BE-0l 

5 1.83E-01 1.83E-01 1. 53E-01 1.53E-0l 

10 1.50E-0l 1.50E-01 1.48E-0l 1.48E-01 

50 1. 43E-01 1.43E-01 1. 42E-01 1. 42E-01 

100 1. 35E-0l 1.35E-Ol 1.35E-01 1.35E-01 

500 9. 12E-02 8. 89E-02 9.06E-02 8. 82E-02 

Pu-239(Y) 1 5.87E-0l 5.88E-Ol 5.88E-0l 2.BE-Ol 2.l3E-0l 2.l4E-01 

5 1. 85E-Ol 1.86E-01 1. 86E-01 1.53E-01 1. 53E-Ol 1. 53E-Ol 

10 1.53E-Ol 1.53E-01 1.53E-0l 1. 48E-0l 1.48E-01 1.49E-01 

50 1.47E-01 1.47E-01 1.47E-01 1.42E-01 1. 42E-Ol 1.42E-Ol 

,.' 100 1.41E-01 1.40E-Ol 1. 41E-Ol 1.35E-Ol 1. 35E-Ol 1.35E-Ol 

500 1. 03E-Ol 1.03E-01 1.03E-ol 9.06E-02 8. 82E-02 9.09E-02 

45 
Table 6.1.3 Validation of Ingestion Results 

24-HOUR URINE WHOLE-BODY 24-HOUR FECES 

NUCLIDE DAY BNL REMedy BNL REMedy BNL 

(CLASS) 

Co-60 1 1.25E-02 1.20E-02 7.lOE-01 7.llE-01 2.77E-01 2.77E-

£1=0.05 5 S.50E-04 9. 12E-04 3. 59E-02 3. 68E-02 2. 99E-02 2.99E-1 

10 4.54E-04 4.90E-04 1. 43E-02 1.4SE-02 4.01E-04 4.16E50 2. 99E-05 2. 99E-05 7.51E-03 7.43E-03 O.OOE+OO 1.2SE-1 

100 1.56E-05 1.52E-05 5.95E-03 5.96E-03 6.51E500 2.09E-Oti 1. 75E-06 2.72E-03 2.72E-03 7.50E-1 

Sr-90 1 5.4SE-02 5.48E-02 7.1SE-01 7.22E-01 2.27E-01 2.23E-1 

£1=0.3 5 1.30E-02 1.40E-02 1.5SE-01 1.61E-0l 2.26E-02 2.33E-i 

10 5.60E-03 5.95E-03 9.90E-02 9. 81E-02 1.BE-03 1.20E-1 

50 1.lOE-04 1.07E-04 5. 63E-02 5. 62E-02 1.93E-05 1.SSE-t 

100 7.lSE-05 7.1SE-05 5.11E-02 5.10E-02 1.26E-05 1.27E-1 

500 1. 62E-05 1.67E-05 3. 45E-02 3.43E-02 2.S6E-06 2.94E-1 

1-131 1 6.02E-01 5.97E-01 3.16E-01 3.21E-01 O.OOE+OO O.OOE+I 

£1=1.0 5 2.52E-04 2.31E-04 1.94E-01 1. 95E-01 O.OOE+OO O.OOE+I 

10 3.09E-04 3.00E-04 1.25E-01 1.25E-Ol O.OOE+OO O.OOE+1 

50 1.S7E-05 1. S9E-05 3.30E-03 3.33E-03 O.OOE+OO O.OOE+( 

100 1.99E-07 2.02E-07 3. 29E-05 3. 34E-05 O.OOE+OO O.OOE+I 

Cs-137 1 2. SOE-02 1.S0E-02 9. 65E-01 9. 77E-01 6.99E-03 4.5lE-( 

£1=1.0 5 1.03E-02 1. 12E-02 S.89E-Ol S.95E-Ol 2.57E-03 

10 5.20E-03 5.4SE-03 S.48E-01 S.50E-01 1.33E-03 

50 3.3lE-03 3.32E-03 ti.55E-01 6.56E-Ol S.28E-04 -( 

100 2.4lE-03 2.4lE-03 4. 76E-Ol 4.77E-01 6.02E-04 6.04E-( 

500 1. S9E-04 1.89E-04 3.74E-02 3.74E-02 4.72E-05 4.73E-( 

U-235 1 2. 34E-02 2.43E-02 7.05E-01 7.04E-Ol 2.72E-01 2. 72E-( 

£ 1 =0.05 5 1.l5E-03 1.1SE-03 3.42E-u2 3.46E-02 2.96E-02 2.96E-( 

10 7.25E-04 7. 49E-04 1. 23E-02 1.26E-02 2.07E-04 2.07E-( 

50 6.76E"';'05 6.86E-05 3.0lE-03 3.03E-03 O.OOE+OO O.OOE+( 

100 1. BE-OS 1. 14E-05 1.50E-03 1.50E-03 O.OOE+OO 

500 1.68E-07 1.ti7E-07 1.11E-03 1.IIE-03 

Pu-239 1 3~3IE-07 2.13E-07 7.18E-01 7.lSE-01 2.S2E-Ol 2. S2E-C 

£ 1=lE-4 5 7.42E-OS S.6IE-08 1.8SE-02 1.S8E-02 3.l4E-02 3.l4E-( 

10 2. 84E-OS 2.94E-08 2. 26E-04 2. 26E-04 2.20E-04 2.20E-C 

.' . -,;. 50 1.l3E-OS 1.14E-08 9.67E-05 9.67E-05 O.OOE+OO 9.67E-( 

100 7. 64E-09 9. SSE-OS 9.5SE-05 6.5IE-C 

500 2.70E-09 9.25E-05 9.25E-05 2.30E-C 

Am-241 1 4. 34E-05 4. 34E-05 7.l8E-0l 7.ISE-01 2. S2E-OI 2. S2E-C 

f 1 =5E4 5 1. 65E-OS 1.26E-OS 1.92E-02 1.92E-02 3.l4E-02 3.l4E-C 

10 1.49E-OS 1. lIE-OS 5.78E-04 5.78E-04 2.l9E-04 2.l9E-O 

50 1. 49E-OS 1.IIE-08 4.49E-04 4.54E-04 O.OOE+OO O.OOE+C 

100 1.49E-08 1. lIE-OS 4.4SE-04 4.49E-04 O.OOE+OO O.OOE+O 

500 1.46E-08 1.0SE-08 4.42E-04 4. 44E-04 O.OOE+OO 0 

46 
Table 6.1.4 Validation of Thyroid Retention Results 

NUCLIDE DAYS BNL REMedy DOSEDAY 

(CLASS) 

I-I3I(D) 1 I.33E-0l 1. 68E-OI I.32E-OI 

5 I.20E-OI I.22E-OI I.23E-OI 

10 7.5IE-02 7.72E-02 9.77E-02 

50 1. 82E-03 2.06E-03 2.50E-03 

100 1.80E-05 2. 26E-05 

500 

47 
6.2 Applications and Limitations of IRF Values 

This manual is a compiliation of an evaluated approach for interpreting 

measurements of radioactivity in body organs, in the whole body or in excreta 

in terms of the quantity of radioactive material taken into the body. 

Calculations based on information in this manual provide a mechanism to 

determine compliance with regulations on the intake of radioactivity and 

equivalent. Estimates of intake are needed not only to assess dose but to 

determine the need for medical follow-up on significantly exposed workers. 

Section 2 describes a method to obtain intake retention functions. These 

functions give the fraction of intake expected to be present in a bioassay 

compartment at any time after an acute exposure. Because these functions are 

a relationship between bioassay measurement and intake, and because intake and 

effective dose equivalent are directly related in ICRP Publication 30, this 

manual provides a way to combine external and internal doses, a proposed 

requirement of the NRC and a recommendation of the ICRP. 

Tables of intake retention fractions (IRFs) are provided for estimating 

inhalation or ingestion intakes for about 100 different nuclides. These 

tables give the fraction of intake retained in the lungs, systemic region of 

the body, gastrointestinal tract, nasal passages, thyroid (for iodine), the 

whole body, accumulated excreta, and 24-hour collections of excreta as a function of time post intake. Intakes are easily determined by dividing the value 

of the bioassay measurement by the appropriate fraction given in the tables. 

This manual provides guidance for the design and conduct a bioassay program. 

Examples are given for the determination of derived investigation levels above 

which further measurement to estimate committed effective dose equivalent and 

other appropriate investigations and actions should be made. Derived in 

gation levels are listed for several commonly used radionuclides for vari 

monitoring frequencies based on recommendations of ICRP. However, other 

factors may effect one's choice for derived investigation levels and monitoring frequencies. These factors may be related to plant operating history, 

equipment availability or specific NRC recommendations. Methods to determine 

the minimum monitoring frequency are provided along with sensitivity 

requirements. 

6.2.1 Pitfalls Associated with Interpreting Bioassay Measurements 

On the basis of independent validation studies, it is concluded that the tabular results accurately represent retention fractions and excretion fractions 

that are based on the models and calculational methods outlined in the manual. 

Thus, computational errors encountered when one calculates an IRF are avoided 

by use of tabulated values. Further, it is concluded that the methods of ICRP 

are accurately represented by the mathematical models used here. Some care 

must be exercised when excretion fractions expected at one day or less post 

intake are used in order to estimate intake from alternative models that use 

or don't use the ICRP transfer compartment. However, in most cases this 

difference is minor and in all cases this difference does not impact the 

tabulations beyond several days post intake. Because the retention of any 

transfer compartment is, in fact, included in the empirical uptake retention 

functions for the systemic whole body and because ICRP only included its 

transfer compartment for mathematical convenience, the authors of this report 

agreed to exclude it from the bioassay models presented here. 

48 
It is unrealistic to assume that individual results will fit model results in 

most exposure cases. Verification studies indicate that a reasonably accurate 

estimate of intake is derived from 3 to 10 measurements on excreta. On-theother-hand, an accurate estimate of intake is derived from fewer in vivo 

measurements. Obtaining several measurements in sequence may identify the 

need for (1) correcting intake estimates for particle size differences; (2) 

adjusting intake estimates for single versus multiple or continuous intakes; 

and (3) adjusting intake estimates for an accurate time post intake. These 

adjustments are made by using methods given in Appendix A and Appendix B of 

this manual and use of these adjustments may in some cases provide a better 

fit of the bioassay measurements when compared to expectation values. 

However, many assumptions are required to translate bioassay measurements into 

estimates of intake and internal radiation doses. In most cases, it is 

practical to assume 1 micrometer particle size and use Reference Man models 

unless specific information is obtained for the exposed individual or for the 

physical and biochemical characteristics of the inhaled or ingested radionuclide. It is our experience that the variance associated with the stochastic nature of radioactive decay is overshadowed by the variance associated 

with the behavior of radioactive materials within the body. Thus, propagating 

only the counting error into the estimate of intake is not recommended. It is 

our recommendation that the best estimate of intake be made from an unweighted 

and minimized value of the chi-squared statistic. Thus, equation 3.1 in 

section 3.1, or equation A.2.4 in Appendix A, should be used with a series of 

measurements associated with exposure of an individual. 

It is our experience that following an accident, a large portion of the intake 

will be in the fecal and urinary excreta eliminated during the first 5 days 

after an accident. The best estimate of intake may be determined by obtaining 

measurements on the first 5 days of excreta, particularly fecal excreta. 

Fecal sample results will help one to focus on the appropriate inhalation 

class. If one misses the first 5 days of excreta, large error in estimating 

the intake from excreta measurements could be encountered because one is 

forced to examine only a tiny fraction of the intake which may then be eliminated each day. Because of this the following bioassay strategy is noted. 

After the first few days post intake, the behavior of radioactive materials in 

the body is described by'parameters which apply over an extended period of 

time. These long-term p§rameters dominate model results for time post intake 

greater than a few days so that models are applicable over the time period 

from intake to excretion. Users of ICRP models should be aware that shortterm-observations of small fractions of the intake, which may be excreted from 

the body each day after the intake, may not be the optimum way to obtain 

bioassay measurements. That is, after the first week passes, if radioactive 

material is measured 5 times in urinary samples which are collected 5 days in 

a row, and if the majority of the fraction of intake which remains in the body 

is to be excreted from the body over a much longer period of time, such as 

months to years, the estimate of intake may be better determined by obtaining 

the 5 measurements spaced evenly over a longer duration of time. In this way, 

errors due to short-term changes in metabolism are avoided, and the parameters 

which are associated with the long-term portions of the metabolic model are 

appropriate for the bioassay collection strategy. 

49 
6.3 Recommendations for Further Study 

Good case studies for verification of bioassay excretion models are difficult 

to obtain. When accidents do occur, it is important that the maximum poss 

information be obtained from bioassay measurements to verify and improve 

assay models. 

There appears to be a paucity of evaluated bioassay data applicable to a 

verification of the computational models and biokinetic parameters presented 

in this report. Further study should be devoted to refinement of models and 

parameters using actual bioassay results from studies involving exposure of 

humans. When significant accidental intakes occur, one should immediately 

collect nasal smears and urine and fecal samples, document. the times of 

collection post-intake, and perform measurements on the collected samples and 

the body. Such measurements should be made even when it may be known that the 

exposure may be insignificant with respect to regulatory limits. To avoid 

undue concern among exposed workers, it should be explained that such measurements are voluntary and are being taken to improve the models. 

Accidental intakes of transuranic radionuclides are usually followed by 

administration of the chelating agent diethylenetriaminepentaacetic acid 

(DPTA) in order to accelerate the excretion of bone-seeking radionuclides and 

to prevent their deposition on bone surfaces, and the soft tissues. Models 

should be developed for chelated radionuclides in order to estimate the 

urinary excretion of transuranic materials following an intake. Because of 

the enhanced excretion following chelation, research might be considered on 

workers known to have large exposures in the past. It may be possible to 

establish a relationship between chelated urinary excretion and the worker's 

current burden and perhaps his original intake. 

Within the radiation worker community there is an expanding group of peop 

who produce or administer radiopharmacuetical substances and there is a need 

to develop models for the retention and excretion of these substances. 

In many instances, ICRP Publication 30 provides several values for f1' the 

fraction in the gastrointestinal tract which is absorbed into the blood. We 

have chosen the values which we feel are most common for worker exposures. 

Additional tabulations~ for different values for f1 should be made. 

Our tabulations apply to Reference Man and in most cases this is the appropriate model to use following accidental exposure. However, it is known that 

retention of certain nuclides varies with organ size and body weight, most 

notably iodine, cesium and strontium. Additionally, f1 may vary with age of 

the person and this has been observed for plutonium. Other factors such as 

bone turnover rate, differences in organ uptake as a function of age, and 

remaining lifespan influence either the retention or the dose assessment and 

these influences may be considerable for infants and children. Methods to 

interpret bioassay measurements for these circumstances should be developed. 

50 
7. SUllWtY 

Bioassay is the final measurement used to assure adequate protection of workers 

from internal radiation exposure. Intake retention functions that are based 

upon Reference Man metabolic models can be used in the design and conduct of a 

bioassay program. Programs designed in this way will help to ensure that significant internal exposures are detected, properly investigated, and recorded. 

Intake retention functions provide a way to make a rapid initial assessment of 

the significance of bioassay results in terms of an estimated intake. This 

assessment is needed to identify those exposures that require further investigation and action. The intake that is estimated from the quotient of the 

measured content of a bioassay compartment and the value of the compartment's 

intake retention function can be compared to either the current NRC quarterly 

intake limit or the ICRP Publication 30 Annual Limit on Intake in order to 

determine the significance of the bioassay result. The quotient of the 

estimated intake of a radioelement by its respective stochastic ALI value when 

multiplied by 5 rem gives an estimate of the committed effective dose equivalent 

of an exposed worker, which then can be added to the worker's external effective 

dose equivalent in order to determine his total radiation exposure status. In 

eases of significant exposures, follow-up bioassay procedures should be used to 

confirm and make better estimates of the intake. Eollow-up bioassays help to 

improve the accuracy of dose estimates. Routine bioassays help to identify 

trends in the internal exposure of the worker; trends that may indicate either a 

need for greater control of the working environment or the need for requalification training of individual workers. 

When a number of bioassay measurements are used to evaluate an internal 

radiation exposure incident, an intake retention function derived from IeRP 

Publication 30 or other current metabolic models can be used as the expectation 

fitting function. The amount of the intake is that which gives the best fit of 

the individual measurements to their respective expectation values. A simple 

fitting procedure, which relies on an expectation function derived from 

Referen~e Man metabolic models, provides an estimate of the intake. Because of 

the usually poor and limited bioassay data that are normally available in an 

exposure incident and because of the complex pattern associated with (1) uptake 

from compartments in the respiratory and GI tracts, (2) the recycling of a 

radionuclide in systemic compartments, and (3) final excretion from the body, 

generally it will not be possible to resolve an individual's metabolic parameter 

values from the bioassay data. However, a series of bioassay measurements may 

help in determining the most appropriate ICRP lung classification, as well as 

the effective AMAD of inhaled aerosols, which can be used to improve the accuracy of the estimated intake and associated committed effective dose equivalent. 

Another helpful measure in aSSigning the appropriate lung classification is the 

fecal to urine ratio of activity, and this may be compared to the 24-hour IRFs 

for feces and urine, which are listed in the tables. 

In serious exposure cases, more detailed evaluations may be required. In such 

cases or when exposures might provide bioassay data that can be used to validate 

or improve the models used in this guide, users of this report are encouraged to 

make such detailed evaluations even if the estimated ~oses may not warrant such 

evaluations. To avoid undue concern regarding exposures, the purpose of such 

evaluations and all other pertinent information should be communicated to 

workers prior to the initiation of such special bioassay. 

51 
8. BIBLIOGRAPHY 

Ad86 Adams, W.B., Engle, J.R., Harper, J.A., Heotis, P.M., and Scott, 

W.A., 1986, Medical Status of Marsha1lese Accidentally Exposed to 

1954 BRAVO Fallout Radiation: January 1983 through December 1984, 

Brookhaven National Laboratory Report, BNL 51958, Upton, New York~ 

ANSI86 American National Standards Institute, Health Physics Society Working. 

Group WG 2.5, June 1986, ANSI 13.30, "Draft Performance Criteria for 

Radiobioassay." 

Bi86 Birchall, A., 1986, "A Microcomputer Algorithm for Solving Compartmental Models Involving Radionuclide Transformations," Health 

Physics, 50, pp. 389 - 397. 

Can Caldwell, R., 1972, "Evaluation of Radiation Exposures", Health 

Physics Operational Monitoring, Vol. 1, 590 (New York: Gordon and 

Breach). 

FR86 Federal Register, Thursday January 9, 1986, Part II, Nuclear Regulatory Commission, 10 CFR Parts 19 et. a1., Standards for Protection 

Against Radiation; Proposed Rule; Extention of Comment Period and 

Republication, V51,6, pp. 1092-1216. 

ICRP68 International Commission on Radiological Protection, 1968, Evaluation 

of Radiation Doses to Body Tissues from Internal Contamination due to 

Occupational Exposures, ICRP Publication 10, 87 (Oxford: Pergamon 

Press) • 

ICRP71 International Commission on Radiological Protection, 1971, The 

Assessment of Internal Contamination Resulting from Recurre~or 

Prolonged Uptakes, ICRP Publication 10At 7 (Oxford: Pergamon Press • 

ICRP72 International Commission on Radiological Protection, 1972, Alkaline 

Earth Metabolism in Adult Man, ICRP Publication 20, (New York: 

Pergamon Press). 

ICRP74 International Commission on Radiological Protection, 1974, Reference 

Man, ICRP Publication 23, (New York: Pergamon Press). 

ICRP77 International Commission on Radiological Protection, 1977, The Recommendations of the International Commission on Radiological Protection, ICRP Publication 26, (New York: Pergamon Press). 

ICRP79 International Commission on Radiological Protection, 1979, Limits for 

Intakes of Radionuclides by Workers, ICRP PUblicat.ion 30 (New York: 

Pergamon Press). 

ICRP82 International Commission on Radiological Protection, 1981, Limits for 

Intakes of Radionuclides by Workers, ICRP PUblication 30 Part 3 

Including Addendum to Parts 1 and 2 (New York: Pergamon Press) 

ICRP83 International Commission on Radiological Protection, 1983, 

Radionuc1ide Transformation, Energy and Intensity of Emissions, ICRP 

Publication 38, 1163 (Elmsford: Pergamon Press). 

52 
ICRP85 International Commission on Radiological Protection, 1985, The 

Metabolism of Plutonium and Related Elements, Report of an ICRP Task 

Group, ICRP/85/C2-4/1. 

J085 Jones, S.R., 1985, "Derivation and Validation of a Urinary Excretion 

Function For Plutonium Applicable Over Tens of Years Post Uptake", 

Radiation Protection Dosimetry, 11, pp. 19-27. 

M086 Moorthy, A., Schopfer, C., and Lessard, E., 1986, Bioassay Analysis 

Using Fission Track and Urine, Detection of Attocurie Levels of Pu239, Brookhaven National Laboratory Publication, In preparation. 

NCRP85 National Council on Radiation Protection and Measurements, 1985, 

Induction of Thyroid Cancer by Ionizing Radiation, NCRP Report No. 

80, Bethesda, Maryland. 

NRC 84 Nuclear Regulatory Commission, 1984, Title 10, Code of Federal 

Regulations, Part 20, Standards for Protection Against Radiation, 

U.S. Nuclear Regulatory COmmission, Washington, D. C. 20555. 

Ri52 Riggs, D.S., 1952, "Quantitative Aspects of Iodine Metabolism in Man" 

Pharmacol. Rev. 4, 284-370. 

Sk80 Skrable, K. W., Chabot, G. E., and Johnson, M. H., 1980, "Recycling 

Retention Functions," Proceedings of Third International 

Radiopharmaceutical Dosimetry Symposium, Oak Ridge, Tennessee, pp. 

392 - 412, October 7 - 10, 1980. 

Sk81 Skrable, K. W., 1981, Estimate of Radionuclide Intakes from Bioassay 

Data, Part I - Intake Retention Functions, unpublished report. 

Sk83 Skrable, K. W., 1983, "Retention Functions and Their Applications to 

Bioassay and Internal Dose Estimation," manual and presentation at 

Health Physics Society 1983 Summer School on Internal Radiation 

Dosimetry, June 12 - 17, 1983, University of Maryland at Baltimore 

County, Catonsville, Maryland. 

Sk85 Skrable, K. W., Chabot, G. E., Alexander, E. L., and French, C. S., 

1985, "A Discussion of the Arguments Against a Committed Dose 

Limitation System," J. Soc. for Radiological Protection, 5, pp. 59 - 66. 

USDHEW70 United States Department of Health, Education and Welfare, Public 

Health Services, 1970, Radiological Health Handbook, Rockville, 

Maryland. 

53 
APPBRDIX A 

D.AJIPLB OF USE ARD VBl.lrlCATIOIf BASED OR ACTUAL BXPEltlEliCES 

1. DmlOOOClIOIl 

Bioassay models may be tested by comparing calculated estimates of excreted 

radionuclides with bioassay measurement results obtained from actual workers 

who have been accidently contaminated. 

Because the excretion of radionuclides may be influenced by diet, the health 

condition of the worker; age and level of physical and metabolic activity, and 

voiding frequency, variation from predicted results and individual variability 

should be expected. 

There are other possible reasons for actual bioassay data to vary from expected results. Several simplifying assumptions are used in bioassay models, 

e.g. the lung clearance classifications (D, W, and Y) are known, and particle 

size distributions have a characteristic 1.0 micrometer activity median aerodynamic diameter. The solubility of the inhaled radionuclide and the actual 

particle size distribution are often not known. The time at which a urine or 

feeal sample was obtained may not have been well-documented. Additionaly, it 

may not be known whether the sample represents a complete or partial sample. 

In the general evaluation of bioassay results, assumptions regarding volume of 

urine excreted per day or total mass of feces excreted per day may be 

necessary due to the lack of specific detail. Using Reference Man (ICRP74) 

one assumes a daily urinary excretion of 1.4 L/day and a mass of fecal 

excretion of 135 g/day. 

Some of the examples in the following sections have been modified so that 

specific persons cannot be identified with specific times or places. On the 

other hand, the measurements are real and reflect the uncertainty associated 

with the interpretation of bioassay measurements. 

A-I 
2. DUlALA.TIOH 01' ClASS D URANIUM 

An accident happened and some UF6 was accidentally released from Sequoyah 

Fuels Corporation's Facility at Gore, Oklahoma. In order to assess the pu 

health impact associated with it, urine samples were collected and analyzed 

for uranium. The results showed the maximum uranium intake among on-site 

workers was approximately 28 mg (AHIPHATF86). The estimated effective dose 

equivalent for this worker was approximately 0.46 mSv (46 mrem). The dose to 

the maximally exposed off-site individual, based on uranium bioassay measurements, was calculated to be 0.014 mSv (1.4 mrem). The potential dose to a 

maximally exposed off-site resident based on source term and plume modeling 

calculations was 0.022 mSv (2.2 mrem). These radiological doses are insignificant compared with the background radiation of 1.06 mSv/yr (106 mrem/yr) in 

the area. 

The following is an example showing how to use tables presented here to assess 

the intake for three people, whose urine samples were collected and measured. 

From the tabulation for Class D inhalation of uranium, obtain the fractional 

values of intake in accumulated urine. Decay correction is not necessary 

because of the very long halflives of U-234, U-235 and U-238. Calculate the 

accumulated U in urine excreta as follows: 

where: 

ti - ti-I 

Ci x 1.4 L/day x 8ti 

8A1 + 8A2 + ••• + 8Ai 

i m sequence number of sample, 

(A.2.1) 

(A.2.2) 

(A.2.3) 

ti = time post intake for ith sampling (days)lh 

Ci = concentration of uranium in urine from i sampling (pg uranium 

per liter), 

AAi = uranium in ith urine sample (Pg uranium), 

Ai = uranium in accumulated urine up to time = ti (Pg uranium), 

and 1.4 L/day is the daily urine volume for Reference Man. 

!!'he best 

I == 

where: 

estimate of 

f riAi 

t 2 

i r i 

the intake is: 

(A.2.4) 

I = best estimate of intake in pg (or Bq for radioactivity), 

Ai = sample measurement, pg (or Bq for radioactivity), 

ri - fraction of intake in accumulated urine at time of ith sampling. 

Values of ri' for sampling times shown in Table A.2, were obtained from the 

Table on page B-163. 'fhe results can be seen in Table A.2. Some sampling 

times are not listed on page B-163 and values for ri were determined from 

equation 2.5.1 for these times. 

A-2 
Table A.2 Exa~le of Intake Esti.ates Based on Ifeasure'EBts 

of Uramu. in Urine 

Calculated Estimated 

Time of Cone. Of Frac. of Value of Best 

Sample Uranium Intake in Uranium in Estimate 

Individual Post Intake, in Urine, Accum. Accum. of Intake, 

Number ti (days) Ci (llg/l) Urine, ri Urine, Ai (llg) I{llg) 

1 0.20 6,100 0.0500 1,700 

1 0.60 990 0.132 2,300 

1 2.0 90 0.259 2,500 

1 3.0 210 0.291 2,700 1.IE04 

2 0.20 9,600 0.0500 2,700 

2 0.40 2,600 0.0950 3,400 

2 0.80 1,300 0.162 4,100 

2 2.8 220 0.287 4,700 2.1E04 

3 0.36 540 0.0867 270 

3 0.50 310 0.114 330 

3 0.65 110 0.140 350 

3 2.0 8 0.259 370 

3 2.8 12 0.287 380 1.7E03 

Values for the best esti~te of intake were based on the minimum value of the 

chi-squared statistic, X , which is defined as the ratio of the sum of the 

squares of the differences between2measured values, Ai' and expectation 

values, <riI >, and the variance, 6 i

• Thus, 

and for constant variance, equation A.2.4 is the result. Values measured for 

individual number 2 have been plotted versus calculated values in Figure A.2.1. 

The calculated mass of natural uranium in urinary excreta was determined by 

multiplying the best estimate of intake by the fraction of intake in accumulated 

urine. 

A-3 
en 

en 

<! 

~ 

...J 

~ o 

.... 

2 

BEST ESTIMATE OF INTAKE= 2.1 E4p.O URANIUM 

o 

o 

o 

o 

o MEASURED MASS I fL9 

- CALCULATED MASS ,fLO 

'0.00 0.40 0.80 1.20 1.60 2.00 2140 2.80 3.20 

TIME POST INTAKE, DAYS 

FIGURE A.2.1 Calculated and Measured Values for Uranium 

Excreted to Urine from Individual Number 2 

Following Inhalation of Uranium Hexafluoride. 

A-4 
3. IlftIALATIOH OF CLASS D Cs-137 and CI..A.SS W Co-60 

Through routine whole-body counting of personnel at a national laboratory, 

workers were found with detectable body burdens of both Cs-137 and Co-60. 

Monitoring was at one year intervals; thus, we assumed the intake occurred 

just after the last monitoring, or one year previous to sampling. 

The whole-body monitoring results were as follows: 

Case Incorporated Nuclide (Amount) 

1 Cs-137 (52 Bq) ; Co-60 (192 Bq) 

2 Cs-137 (133 Bq) ; Co-60 ( 48 Bq) 

From the Class D and Class W tables (pages B-111 and B-212), the tot~~ body 

retention_2ractions for Cs-137 and Co-60, respectively are 5.93 x 10 and 

1.30 x 10 • Class W was assumed for Co-60 because the associated committed 

effective dose equivalent was greater than that computed by as summing Class 

Y. The retention fraction at 365 days post intakb was obtained from 

interpolation between the values tabulated for 300 and 400 days. 

The estimated intakes are as follows: 

Case Estimated Intake 

1 192/(1.30 x 10-2) ... 14,800 Bq for Co-60 

52/(5.93 x 10-2) = 878 Bq for Cs-137 

2 48/(1.30 x 10-2) III 3,700 Bq for Co-60 

133/(5.93 x 10-2) - 2,240 Bq for Cs-137 

The stochastic ALI yalues for the inhalation of Class W Co-60 and Class D Cs137 are both 6 x 10~q. Thus, estimates of the committed effective dose 

equivalent are: 

Case 

1 

2 

Estimated Committed Effective Dose Equivalent 

878 

(6.0E+06 

(2,240 

6.0E+06 

+ 14,800 ) 

6.0E+06 

+ 3,700 ) 

6.0E+06 

x 0.05 Sv ... 1.3E-04Sv (0.013 rem) 

x 0.05 Sv = 4.95E-05Sv (0.0050 rem) 

Because of the conservative assumptions about the time of intake, doses are 

probably less than the estimates above. 

A-5 
4. RADIOIODINE INGESTION ARD IRBAIATION 

Case I: Ingestion of 1-131 

A known amount of 1-131 was given to a patient for diagnostic purposes (L1 

The patient was found to have normal thyroid function. On the 7th day after 

iodine administration, bioassay was started and included in vivo measurements 

and analysis of the nuclide concentration in urine samples. Experimental data 

from the patient are shown in Table A.4.1, together with the Appendix B intake 

retention fractions. 

Based on comparison of experimental and Appendix B lRFs, we conclude that the 

iodine models for ingestion and for systemic iodine incorporation are 

representative of the patient's metabolism of iodine. When monitoring is done 

through urine analysis, samples have to be repeated to reduce the uncertainitY 

associated with normal fluctuations, which are expected due to daily differences in diet. Urine data were also influenced by the assumption of a 24-hour 

urinary volume of 1.4 liters. However, in vitro bioassay through urine 

analysis is a good method of detection of abnormal situations. 

table A.4.1 ComparisOD of Patient's Results witti IRPs in 

Appendix B (p. B-581) for Iodine-Ill 

Time After Measured Fraction Appendix B 

Intake of Ingested for 1-131: 

Activity In: 

----------------------------- days Total Body 24-Hour Urine Total Body 

7 1.8E-01 1. 63E-01 

8 1.5E-01 3.9E-04 1.49E-01 

9 3.6E-04 

10 3.5E-04 

20 4.7E-02 1.3E-04 5.10E-02 

40 3.4E-05 

A-6 

IRFs 

24-Hour 

2. 93E-04 

2. 99E-04 

2. 99E-04 

2.00E-04 

4. 32E-05 
Case II: Accidental Overexposure by Inhalation 

A worker involved in 1-131 labeling of radiopharmaceutical substances was 

accidentally overexposed (Li85). This was detected by abnormally high concentrations of 1-131 in urine samples which were collected on a bi-weekly 

basis. Due to a holiday, there was no work in the week when the sample was 

taken, thus exposure was assumed to have occurred ten days before. The 

accident was due to a problem in the exhaust of the evaporation box, and this 

was reported by the worker. Thereafter, the worker was restricted from 

working in the area where 1-131 labeling was performed. Daily urinary samples 

were taken from day 16 to day 26 after the probable exposure. In vivo 

counting of the thyroid was performed on days 18 and 20. A summary of the 

results for the bioassay measurements is given in the Table A.4.2 together 

with the IRFs expected in urine and in the thyroid. 

Table A.4.2 Bioassay Kesults and IlFs for Accidental Iodine-Ill Inhalation 

Time After 24-Hour Urine 

Accident, Bioassay Result, 

Days Bq 

10 1440 

16 987 

17 970 

18 419 

19 318 

20 378 

21 557 

22 543 

23 574 

24 318 

25 305 

26 311 

30 

24-Hour Urine 

IRF, 

Appendix B 

1.88 E-04 

1.57 E-04* 

1.50 E-04* 

1.42 E-04* 

1.34 E-04* 

1.27 E-04 

1.19 E-04* 

1.11 E-04* 

1.04 E-04* 

9.72 E-05* 

9.06 E-05* 

8.43 E-05* 

6.25 E-05 

Thyroid 

Results, 

Bq 

4.81 E+05 

3.90 E+05 

Thyroid 

IRF, 

Appendix B 

7.51 E-02 

3.55 E-02* 

2.95 E-02 

1.16 E-02 

*Values obtained by interpolation of Appendix B (p. B-103) values 

A best estimate of intake based on the urine bioassay results. which is given 

by equation A.2.4, yields an intake of 4.99 E+06 Bq. A best estimate of 

intake based on thyroid measurements yields 1.34 E+07 Bq. Intake based on 

urinary results is a factor of 2.7 lower than intake based on thyroid measurements. Calculated and measured values for 1-131 in daily excreta are plotted 

in Figure A.4.1. Calculated values were obtained by multiplying 4.99 E+06 Bq 

by the IRF for 24-hour urinary excretion of 1-131. 

A-7 

I 
The early excreta measurement on day 10 tends to agree with intake based on 

thyroid counting. Variation may be due to dietary factors, radiation damage 

to the thyroid or biological variation of the individual; for example, the 

person may be iodine deficient. In this situation, intake should be 

thyroid measurements since radioactivity in the thyroid represents a 

fraction of the intake and since thyroid dose equivalent dominates the 

effective dose equivalent. Thus, the best estimate of intake is 1.34 E+o7 Bq. 

The committed effective dose equivalent per unit of intake, from ICRP 

Publication 30, is 1.4E-08 Sv per Bq. Thus, the committed effective dose 

equivalent is 1.8E-Ol Sv (l.8E+Ol rem). However, in the case of 1-131, the 

committed dose to the thyroid .per unit of intake is given as 4.8E-07 Sv per Bq. 

Thus, the committed thyroid dose equivalent is 6.2 SV (620 rem). Because the 

level of thyroid dose is high, medical follow-up is recommended since late 

effects such as hypothyroidism, thyroid adenoma, and thyroid cancer are 

possible but not highly probable 10 to 30 years after the exposure (Ad86 , 

NCRP85). 

2.00 

1.80 ESTIMATE OF INTAKE = 4.99ES Bq 

cr 

m I.SO .. w 0 MEASURED VALUES 

z _1.40 

D::CJ) 

:::')0 

CALCULATED VALUES 

7 ~ 1.20 

~~ z 01.00 o 0 

-~ 

~-1.80 

> 

tU O.SO 

<{ 

0.40 0 0 

0 o 0 0 

0.2010 12 14 IS 18 20 22 24 2S 28 30 

TIME POST INTAKE, DAYS 

FIGURE A.4.1 Calculated and Measured Values for 1-131 

Activity in One Day Urine Samples for Worker 

in Case II. The Estimate of Intake is Based 

on Urinary Measurements Only. 

A-8 
Case III Unknown Day of Inhalation of 1-131 

In the same installation as in Case II, but two years later, routine bioassay 

monitoring showed the following on two workers:. 

Table A.4.3 1-131 Keasure.ents OIl 'fwo Workers 

Date of Monitoring 

May 

Worker A 

18 

22 

27 

Worker B 

15 

22 

27 

28 

Activity in 

24-Hour Urine, 

Bq Bq 

3500 

2.0 

63 

4700 

62 

17 

Activity in 

Whole Body, 

Background 

4,070 

1,110 

8,140 

2,960 

We conclude, by comparing these results with IRFs from Appendix B (p. B-101, 

103), that the probable time of the exposure of the two workers was between 1 

and 2 days prior to the May 22 whole-body count. This conclusion came from 

analyses of the rate of disappearance of iodine. Results of the analyses are 

shown in Table A.4.4. 

Table A.4.4 Deter.dnation of Uoknown Ti.e Post Intake of Iodine 131 

Assumed 

Day Post 

Intake Date of 

days Measurement 

1 

2 

5 

6 

May 22 

May 22 

May 27 

May 27 

• 24-hour urine activity 

whole-body activity 

•• 24-hour urine IRF 

whole-body IRF 

Worker A 

Ratio· 

8.6 E-01 

8.6 E-Ol 

1.8 E-03 

1.8 E-03 

A-9 

Worker B 

Ratio· 

5.8 E-01 

5.9 E-01 

2.1 E-02 

2.1 E-02 

Appendix B 

IRF 

Ratio·· 

1.1 E+OO 

3.3 E-01 

1.1 E-02 

4.1 E-03 

I 
"' ." . 

The counting error relative to the net count associated with the May 27 urine 

activity is greater than that associated with the May 22 measurements, thus 

the May 22 ratios may be more reliable indicators of time post intake. 

However, day to day variation in individual diet and urinary excretion wi 

generally have greater impact on the result than does counting error. 

These examples illustrate how well the IRFs from Appendix B represent iodine 

incorporation and excretion; although, there are some differences according to 

individual metabolism. Comparing the tables in Appendix B and the data from 

the workers, we conclude that for a single intake: 

(1) bioassay through urinalysis is a method that is truly capable of 

detecting abnormal exposures to 1-131 if it is performed promptly 

after exposure since typical minimum detectable urine activity is on 

the order of 2 Bq (50 pCi) per liter for 1-131, 

(2) in vivo monitoring is useful in order to detect exposures after a 

longer period of time since typical minimum detectable thyroid 

activity is on the order of 750 Bq (20 nCi) for 1-131, and 

(3) in cases where exposure is detected by chance, from routine bioassay 

monitoring, it is useful to have both in vitro and in vivo results in 

order to determine when exposure took place. 

A-IO 
.: 

s. INIIALA.TION 01' THORIUM AND URANIUM 

Case I: Thorium 

For thorium, the amount which is inhaled and subsequently excreted through the 

gastrointestinal tract is much greater than the amount excreted through the 

urine pathway. Additionally, the portion of intake that is cleared to the 

gastrointestinal tract is one that results from the non-systemic deposit. The 

annual limits on intake for Class Wand Class Y 1 micrometer AMAD aerosols of 

thorium 232 are 40 Bq and 100 Bq, respectively. Examination of the IRFs in 

Appendix B provides the follOWing insight into routine bioassay monitoring for 

inhalation of 1 ALI of thorium 232: 

Table A. S.1 IRPs and Urine Activity Corresponding to 1 ~ of 1horiu.-232 

Time After Class W Activity Class Y Activity in 

Intake IRF in 24-Hour IRF 24-Hour 

days 24-Hour Urine Urine, Bq 24-Hour Urine Urine, Bq 

1 5.33E-03 2. 13E-01 2. 85E-04 2. 85E-02 

2 1.42E-03 5. 68E-02 7.81E-05 7.81E-03 

3 4.09E-04 1. 64E-02 2. 23E-05 2. 23E-03 

4 1.54E-04 6. 16E-03 7.88E-06 7. 88E-04 

5 9.04E-05 3. 62E-03 4. 13E-06 4. 13E-04 

For single intake of 1 ALI of thorium 232, we conclude that bioassay through 

urine analyses is not suitable unless one. collects the urine sample immediately 

following the accidental exposure. We also conclude that routine monitoring of 

occupationally exposed persons is not practical if one monitors urinary 

excretion of thorium since recording and investigation levels would be difficult 

to detect since the typical minimum detection limits for alpha counting is 4E-03 

Bq (0.1 pCi) per liter of urine. 

One approach to monitoring workers on a routine basis is to examine the feces 

for thorium 232. The minimum detection limit is on the order of 4E-03 Bq (0.1 

pCi) per feces sample. An excretion corresponding to the ALI would be as 

follows: 

Table A.S.2 IRPs and Peces Activity Corresponding to 1 ~ of 1horiu.-232 

Time After Class W Activity Class Y Activity in 

Intake IRF in 24-Hour IRF 24-Hour 

days 24-Hour Feces Feces, Bq 24-Hour Feces Feces, Bq 

1 4.22E-02 1. 69E+00 5.10E-02 5.10E+00 

2 1.35E-01 5.40E+OO 1.57E-Ol 1. 57E+01 

3 1. 14E-01 4. 56E+00 1.28E-01 1. 28E+00 

4 6. 65E-02 2. 66E+00 7.23E-02 7. 23E+00 

5 3. 42E-02 1.37E+00 3. 59E-02 3. 59E+00 

As an example of occupational exposure, routine monitoring of exposed persons in 

a monazite plant produced the bioassay results which are in Table A.5.3. 

A-II 
Table A.5.3 Thoriu. Levels in Workers and the General Public 

Exposed Group Activity in Activity in 

24-Hour Feces, Bq 24-Hour Urine, Bq 

Class 

Worker 1/1 1.9E+OO 7.0E-02 

Worker fI2 9.0E-01 1.3E-02 

Class Y Exposure 

Worker 113 3.0E-01 7.0E-03 

Worker #4 4.0E-02 below detection limit 

Non-Exposed People, 

Sao Paulo, Brazil 

Mean 5.0E-03 3.0E-03 

A problem with fecal monitoring is that in order to assess exposure to thorium 

232, which has an ALI based on the 0.50 sv (50 rem) committed dose equivalent 

limit to bone surface, one must rely on measurements which reflect the nonsystemic burden of thorium in the lungs. Urine sample results, which are given 

in the above example, are based on samples collected on the last day of the work 

week. If the radiation protection program is successful, urine bioassay should 

not show thorium 232 concentrations in urine significantly higher than detection 

limits and different from comparison samples from non-exposed persons. 

Based on the 24-hour fecal measurement, an estimate of intake and committe 

effective dose equivalent can be assigned to the workers in Table A.5.3. 

on Table A.S.2, one would expect between 1.37 and 5.40 Bq in feces if a 40 Bq 

intake of thorium-232 occurred between 1 and 5 days prior to sampling, for Class 

W materials. Thus, worker III inhaled as little as 14 or as much as 55 Bq. His 

committed effective dose equivalent is bracketed between 0.02 Sv and 0.07 Sv. 

For worker 113, his intake ranged between 1.9 and 8 Bq and his committed 

effective dose equivalent ranged between 9.SE-04 SV and 4.0E-03 Sv. Urinary 

measurements yield wider ranges of estimated intake and dose equivalent by an 

order of magnitude or better. 

In vivo monitoring relies on measurements of nuclides at the end of the thorium 

series, mainly thalium 208, thus requiring an estimate of intake of all 

daughters including radon 220. Therefore, the algorithm used to interpret 

results of in vivo measurements is complex, and variation in particle size and 

the behavior of daughter nuclides would compound the uncertainties which are 

associated with intake and dose equivalent estimates for thorium. Thus, while 

fecal monitoring is not an appropriate way to estimate the thorium accumulated 

in systemic organs, fecal monitoring is the acceptable option for routine 

monitoring. 

The gathering of data for occupationally exposed Th workers and for normal excretion was done by J. Lipsztein, C.A. Nogueira, L. Berteli, A. Fonseca, and J. 

Gaburo from Comissao Nacional de Energia Nuclear, S. Paulo and rio de Janeiro. 

A-12 
Case II: Uranium 

The following discussions regarding uranium are based on the tabulated values in 

Appendix B, and these data are summarized here for uranium 238: 

Table A.5.4 IRFs For Uraniu. 238 

Time Class D IRF Class W IRF Class Y IRF 

After 

Intake, Systemic 24-Hour 24-Hour 24-Hour 

days Region Urine Lungs Urine Lungs Urine 

1 2. 22E-Ol 1.87E-Ol 2.11E-0l 4. 13E-02 2. 14E-01 2. 28E-03 

S 1.6SE-01 1.31E-02 1.4SE-01 2.69E-03 1. S3E-Ol 1.28E-04 

10 1.21E-0l 7.26E-03 1. 32E-01 1.7SE-03 1.49E-01 8.26E-OS 

20 7. 36E-02 3. 26E-03 1. 16E-Ol 1.03E-03 1.47E-01 4. 62E-OS 

100 1. 47E-02 1.11E-04 4. 18E-02 2. 43E-04 1.3SE-0l 1.87E-OS 

Additionally, the ALI's for uranium 238 are SE+04 Bq for Class D, 3E+04 for 

Class Wand 2E+03 for Class Y aerosols having an AMAD of 1 micrometer. The 

minimum detection limit for daily urine sampling is typically 7 ug (1.7E-02 

Bq), and for in vivo lung monitoring 100 Bq. 

For uranium, an appropriate bioassay technique is in vivo lung monitoring for 

class Wand Class Y compounds, and urinary measurement, or in vivo bone 

measurement, for Class D compounds. For Class Wand Class Y compounds, the 

IRF for the 24-hour ur~ne compartment decreases rapidly, and low levels of 

natural uranium in urine make it difficult to assess an accidental exposure. 

Thus, if it is possible to perform in vivo lung monitoring, it should be 

chosen for Class Wand Class Y compounds. 

For Class D compounds of uranium, an appropriate monitoring method is to 

analyze urine samples in the first few days after an accidental intake. After 

a few days, urinary excretion decreases to the extent that in vivo phoswich 

detectors positioned near b9ne, for example the head, are practical. 

In summary and in addition, when dealing with uranium it is important to know 

that: 1) generally exposures are to a mixture of uranium isotopes; 2) when 

dealing with class D compounds of uranium, chemical toxicity of the kidneys is 

more important than radiotoxicity; 3) many bioassay methods are useful if the 

accidental intake is on the order of 1 ALI and measurement occurs during the 

first few days following the accident; 4) routine monitoring of urinary 

samples is appropriate for Class D compounds and marginal for Class W 

compounds of uranium; and S) in vivo counting of the lungs is the best choice 

for routine monitoring of Class Y compounds of uranium; 6) actual exposures to 

uranium have often been found to be comprised of mixture of compound classes 

including a large fraction of Class D compounds. When a significant fraction 

of the intake is from Class D compounds, then this component can be used as a 

A-13 
tracer for the estimation of the intake from all compounds. Thus, it may be 

possible to use urine analysis for the estimation of intake of all compound 

classes of uranium provided some Class D is present and provided the 

distribution of compound classes has been determined from simulated lung 

solubility tests. 

6. 1.'RITIUH EXPOSURE INCIDENT 

A reactor at a national laboratory is moderated, cooled and reflected by heavy 

water. Neutrons interact with the heavy water to produce tritium, thus the 

coolant becomes contaminated with radioactivity. On one occasion, the coolant 

purification system was being used by new employees who had limited experience. The purification system procedures, which were unwritten,at that time, 

called for a hose to be attached from a light water line to the outlet side of 

a resin bed and a second hose to be connected to the inlet side of the bed and 

allowed to drain into a 5-gallon pail. When questioned, the operators who 

were filling the resin bed remembered that they had the light water supply 

connected to the bed inlet and the discharge hose leading to the pail 

connected to the bed outlet, which was the reverse of the procedure. In 

addition, the technician performing the throttling operation inadvertently 

caused a rapid increase in pressure, which resulted in immediate ejection of 

about 3 gallons of tritiated heavy water from the bed into the pail. 

The person closest to the pail received the highest exposure to tritium and 

the following bioassay measurements were recorded. 

Time Post Uri ne Acti vi ty lRF, from Estimated 

Incident, Concentration, Appendix B, Intake, 

days llCi/l Section 6 mCi 

1 5.80 0.0392 0.15 

3 5.53 0.0340 0.16 

9 3.73 0.0224 0.17 

10 4.24 0.0209 0.20 

30 1.21 0.0051 0.24 

The best estimate of intake in this case is obtained from all of the data 

collectively by using equation A.2.4, which gives an intake of 8.4 MBq (0.23 

mCi). This corresponds to a committed effective dose equivalent of (1.0E-04 

Sv) 14 mrem based on the intake to dose conversion factor in IeRP Publication 

30. Our estimate of intake is based on the assumption ofa single exposure to 

tritium. However, persons working at the HFBR received additional chronic 

exposures to low levels of tritium in the course of routine operations, and 

the measurements at 10 and 30 days post the incident are less than ideal 

because they could be affected by this chronic exposure. The only way to 

avoid interference would be to remove exposed persons from the working 

environment until their exposures have been fully evaluated. An ideal case 

history would be a single exposure starting at a known point in time. 

Unfortunately, case histories with ideal characteristics do not usually occur 

in practice. 

A-14 
7. VERIFICATION OF lNIIALATION AND INGESTION MODELS FOR lin-54. Co-60. Sr-90. 

Bb-95. Cs-137. Ce-141. Ce-l44. U-233 and Aa-241 

Actual case studies were used to verify the tabulated results from the 

bioassay model. Four accidental exposure cases were obtained from the 

personnel dosimetry files of a large government nuclear site. The four cases 

represented major internal contamination incidents in which no chelating 

agents were administered in order to accelerate the excretion of internally 

deposited radionuclides. 

Most of the measurements in this section are associated with early excretion 

rates and they do not necessarily verify that the committed dose estimates, 

obtained using the models, are correct. This is because the longer term 

components of retention often dominate the committed dose calculation, and 

these components are not evaluated in. all cases. Howeve;r, Mn-54 and Co-60 

body-burden measurements are evaluated over the long-term, and in the case of 

Pu-239 excretion, Jones has evaluated the longer term components (JoS5). 

It is noted that the total fecal excretion over the first few days is a measure 

of the fraction of the inhaled activity that is deposited on the ciliated 

region of the bronchial tree for "non-soluble" materials, and is essentially 

independant of whether the material is Class W or Y. This integrated early 

excretion is very useful for the early evaluation of the seriousness of an 

inhalation exposure. The ICRP task group that is revising the lung model is 

conSidering having early excretion as an explicit feature of the new model. 

Case I: Inhalation of Mn-54, Co-60, Sr-90, Ce-141 and Ce-144 

A 33-year old, male boilermaker with inadequate protective clothing was 

performing maintenance work on a steam generator when a contamination incident 

occurred involving inhalation of mixed fission and activation products. 

Follow-up dosimetry evaluation included whole-body counting, urine sampling, 

and fecal sampling; however, useful data were not obtained from urine 

measurements. Initial intakes of radionuclides were estimated from whole-body 

counting. Data were subsequently available on the amount of Co-60, Mn-54 , Sr90, Ce-141, and Ce-144 in feces. The inhaled radionuclides were assumed to be 

Class W for Co-60, Ce-141, and Ce-144 and Class D for the Mn-54 and Sr-90. 

This exposure incident was evaluated over a period of about two weeks. 

Case II: Ingestion of Co-60, Sr-90, Nb-95, Cs-137, Ce-141 and Ce-144 

A 35-year old, male maintenance worker, was contaminated with mixed fission and 

activation products during a leak of primary coolant. Internal contamination 

occurred when the worker accidentally ingested an unknown quantity of 

contaminated primary coolant. Dosimetry evaluation included whole-body 

~ounting, urine sampling and fecal sampling. Initial intakes of radionuclides 

were estimated from whole-body counting. Data were subsequently obtained on, 

the amounts of Co-60, Nb-95, Cs-137, Ce-141, Ce-144 and Sr-90 in feces, and on 

Sr-90 in urine. Bioassay results were evaluated over a period of 4-6 days. 

Case III: Inhalation of Highly Soluble, Class D U-233 

A 43-year old, female laboratory-chemistry technician was accidentally 

contaminated when a liquid solution of U-233 standard exploded and sprayed the 

A-15 
victim with a highly soluble, Class D nitrate solution. The intake of U-233 

occurred primarily by inhalation. Follow-up dosimetry evaluation involved 

whole-body counting and urine bioassay. Initial intakes of U-233 were 

estimated from urine excretion results, and urine samples were collected 

period of more than two months. 

Case IV: Inhalation of Class W Am-241 

A 46-year old, male chemistry-process technician was accidently contaminated 

with soluble Am-241 nitrate during a chemical explosion involving a resin ionexchange column. We assumed that the Am-241 solution behaved like a Class W 

compound. This worker received a measurable intake of Am-241 by inhalation. 

Follow-up internal dosimetry evaluation was based on whole-body counting, urine 

sampling and fecal sampling. Initial intakes of Am-241 were estimated from 

whole-body counting, and bioassay results were collected over a period of about 

two weeks following the accident. 

For Case Studies I through IV for Sr-90, Ce-141, Ce-144 and U-233, the initial 

intakes were calculated using excretion measurements and methods described in 

this report. For Mn-54, Cs-137 t Co-60, N6-95 and Am-241, whole-body counting 

measurements and methods described in this report were used to estimate initial 

intakes. All aerosols were assumed to have a 1 micrometer AMAD. Results of 

the bioassay measurements for Cases I through IV are plotted in Figures A.7.1 

through A.7.15. Amounts of radionuclide in urine or feces are plotted as the 

fraction of the estimated initial intake for various times post intake and are 

represented by dots. Expected values from the bioassay model are plotted using 

a continuous line on the same figure for comparison with the observed values. 

Fractions of initial intake in excreta are given in Table A.7.1 along with 

associated IRFs. 

Table A.7.I Verification of Measurements in Terms of Fraction of Intake 

and Tiae Post Intake for Cases I through IV 

Case, Nuclide 

(Bioassay 

Compartment) 

It Co-60 

(feces) 

I, Mn-54 

(feces) 

I, Sr-90 

(feces) 

Time Post 

Intake, days 

0.5 

1.5 

4.5 

20.5 

0.5 

1.5 

4.5 

20.5 

0.5 

1.5 

4.5 

15.5 

A-16 

Measured 

Fraction 

of Intake IRF* 

6.73E-2 l.lOE-2 

4.00E-l 1.04E-l 

3. 18E-3 4.61E-2 

1.38E-4 1.10E-3 

2.45E-2 9.94E-3 

1.14E-l 6.21E-2 

1.08E-3 6.78E-3 

7. 24E-5 6.06E-4 

2.49E-2 1.89E-2 

1.11E-l 5. 83E-2 

2. 68E-3 1.0IE-2 

8. 66E-3 7.68E-4 
Table A. 7.1 Continue4 

Case, Nuclide Time Post Measured 

(Bioassay Intake, Fraction 

Compartment) days of Intake IRF· 

I, Ce-141 0.5 2.47E-2 5. 22E-3 

(feces) 1.5 1.74E-l 9. 78E-2 

4.5 6. 17E-4 4. 36E-2 

I, Ce-144 0.5 3. 82E-2 4.lOE-3 

(feces) 1.5 2. 72E-l 1.0IE-l 

4.5 2.93E-3 4.70E-2 

II, Co-60 0.5 1.30E-l 7.26E-2 

(feces) 1.5 3.35E-l 4.18E-l 

2.5 1.51E+O 2.73E-l 

II, Nb-95 0.5 8. 95E-2 7.07E-2 

(feces) 1.5 1. 64E-l 4. 16E-l 

2.5 1.1OE-l 2. 62E-l 

II, Cs-137 0.5 2. 42E-3 3.46E-3 

(feces) 1.5 7.55E-3 6.13E-3 

2.5 4.26E-3 4.61E-3 

II, Ce-141 0.5 1.83E-l 7.17E-2 

(feces) 1.5 3.14E-l 4.21E-l 

2.5 '2.13E-l 2.73E-l 

II, Sr-90 0.5 1.06E-l 6.60E-2 

(feces) 1.5 3. 62E-l 3. 16E-l 

2.5 1.60E-l 1.98E-l 

3.5 2. 88E-3 8.70E-2 

4.5 1.13E-3 3.50E-2 

II Sr-90 0.5 5.23E-2 4.30E-2 

(urine) 1.5 2. 16E-2 2.83E-2 

2.5 1.39E-2 2. 16E-2 

II Ce-144 0.5 1.84E-l . 7.17E-2 

(urine) 1.5 3.45E-l 4. 32E-l 

2.5 2.09E-l 2.85E-2 , . 

III U-233 0.5 3. 78E-l 1.14E-l 

(urine) 1.5 3. 94E-2 1.17E-l 

15.5 1.22E-3 4.58E-3 

29.5 4. 72E-4 1.76E-3 

63.5 1.40E-4 3.99E-4 

IV Am-241 0.5 4.07E-3 5.25E-3 

(urine) 1.5 1.15E-3 1. 79E-3 

2.5 1.22E-3 1.66E-4 

A-17 
table A.7.1 Continued 

Case, Nuclide Time Post Measured 

(Bioassay Intake, Fraction 

Compartment) days of Intake IRF* 

3.S 6.84E-4 6.0SE-S 

4.S 3. S3E-4 S.3lE-S 

9.S 1.03E-4 S.OOE-S 

10.S 3.93E-4 4.9SE-S 

11.S 1. 75E-4 4.9lE-S 

12.5 1.09E-4 4.87E-S 

13.S 2. 63E-S 4.S2E-S 

IV Am-241 0.5 3.09E-l S.28E-3 

(feces) I.S 6.SSE-2 1.0IE-l 

2.S 9. 27E-3 1.3SE-l 

3.5 2.48E-3 S.93E-2 

4.S S. S2E-4 4.S0E-2 

9.S 3. 23E-4 2.43E-3 

IO.S S. S6E-4 I.SlE-3 

11.S 2.S8E-4 I.S0E-3 

12.S 1.56E-4 1.34E-3 

13.S 6.7SE-5 1.2SE-3 

*Values of IRF were obtained from equation 2.5.1, Section 2.S.1. 

In general, there was agreement between predicted and actual results. The 

values measured for Cs-137, Ce-141, Ce-144 and Sr-90 were closest to those 

predicted. Actual measurements made at early times post-exposure typically 

exceeded the values predicted by the model, which could have resulted from an 

error in the estimate of initial intake. The model did not fit particularly 

well for Co-60 in feces, nor for inhalation of the cerium isotopes. The model 

predicts 2.5 times more than the amount of Nb-95 excreted in feces. 

A weighted estimate of intake can be derived from the definition of the chisquared statistic given in section A.2 and by assuming the variance is that 

associated with counting errors. Since the weight is the inverse of the 

variance, and since the variance is the number of counts for radioactivity 

measurements, the largest values measured will have their impact on best 

esti~te of intake reduced the most. Equation A.7.l is the result of 

propagating the counting error into the best estimate of intake. 

I = A. 7.1 

where: 

I = best estimate of intake, 

Ai = the value of the ith measurement, and 

r i = the IRF associated with the ith measurement. 

A-IS 
If one uses all the data to obtain the best estimate of intake by using 

equation A.7.1 or equation A.2.4, the value of intake should approach 1.0 

since measured values in Table A.7.1 are given in terms of the fraction of 

intake. That is, we can compare intake based on whole-body counting to intake 

based on excretion measurements for the same person. For example, in Case IV 

for Am-241 in urine, the value of intake equaled 0.77; that is, the unweighted 

estimate of intake based on ten urinary activity measurements was 77% of the 

value of intake which was estimated based on whole-body counting measurements. A number of samples may be useful in order to reduce the variation 

associated with estimating intake from excretion measurements, which is 

largely due to daily variations in diet and health, and sometimes due to 

counting errors. Also, a single measurement on an aliquot of a ten sample 

composit would be cost effective. 

The impact of counting error on the best estimate of intake can be inferred by 

comparing all the unweighted and weighted values given in Table A.7.2. The 

mean and standard deviation of theunweighted values are 1.5 +/- 1.1 and for 

the weighted values are 0.73 +/- 0.52. Thus, for these cases it appears that 

weighted values of intake based on excreta measurements tend to underestimate 

the intake. This may be due to the fact that early excretion results are 

given more weight because they have more radioactivity and because IRFs 

underpredict the amount of intake present in early fecal samples (see Table 

A. 7.1). 

The large variations introduced by differences in uptake following inhalation 

of radioactive materials which result from changes in chemical form and 

particle size which may occur after deposition, may be reduced by collecting 

urinary samples several weeks after the intake incident. Thus, in addition to 

collecting early samples, one should follow-up after an appropriate interval 

of time for uptake to occur, which could be several months post intake for 

Class Y material. Thus, collecting and analyzing a nu.mber of urinary or fecal 

samples over a period of time will help to reduce the uncertainity associated 

with the estimate of intake from excreta measurements. 

Table A.7.2 Unweighted Intake Baaed on Excreta Heasure.mts Divided by 

Unweighted Intake Baaed on Whole-Body Counting (U) and Weighted 

Intake Based on Excreta Heasure.mts Divided by Unweighted 

Intake :&qed on Whole-Body Couuting (W) 

Number of Type of 

Case Nuclide Samples Sample U W 

I Co-60 4 feces 3.2 0.23 

I Mn-54 4 feces 1.8 0.93 

II Co-60 3 feces 2.2 1.3 

II Nb-95 3 feces 0.42 0.43 

II Cs-137 3 feces 2.1 1.4 

IV Am-241 10 urine 0.77 0.78 

IV Am-241 10 feces 0.25 0.048 

A-19 
, : -<.-•. "". 

LIJ 

~ 

~ Z 

LL 

0 

z 

0 

~ (.) 

<t 

0:: 

LL 

UJ 

~ 

0.30 

0.20 

0.10 

FIGURE A.7.1 Co-60 Inhalation; Feces; Class W 

• 

0.\ 0 

~ 0.08 

LL 

o 

z 

o 

~ (.) 

<t 

0:: 

LL 

0.06 

0.02 

2 :; 4 5 6 

TIME POST INTAKE (days) 

FIGURE A.7.2 Mn-54 Inhalation; Feces; Class D 

A-20 

7 8 

7 8 
0.10 

w 

:::.:: 

~ z 

0.08 

\.L. 

0 0.06 

z 

0 

.... 

0 0.04 « 

0: 

\.L. 

0.02 

• 

0.000 2 4 6 S 10 12 • 14 16 18 20 

TIME POST INTAKE (days) 

FIGURE A.7.3 Sr-90 Inhalation; Feces; Class D 

0.20 

• 

IJJ 0.15 

:::.:: 

~ z 

LL. 

0 0.10 

z 

0 

.... 

0 

« 

a:: 0.05 LL. • i •• '._, 

" .. 

0.00 OL.oc::;....L----'----'----L.---L---..I

3

-.L.-...L---..--

S

.L.-...L--...&.6-L--...L..-...L---l

S 

TIME POST INtAKE (days) 

FIGURE A.7.4 Ce-141 Inhalation; Feces; Class W 

A-21 
0.25 

w 

~ 

~ 0.20 

z 

lL. 

0 0.15 

z 

0 

t0 0.10 « 

0:: 

lL. 

0.05 

0.00 0 7 e 

TIME POST INTAKE (days) 

FIGURE A.7.S Ce-141 Inhalation; Feces; Class Iv 

1.6 r----r---..,---,.-----,-----r--..,-----,----, 

• 

w 1.2 ~ 

;:! 

Z 

lL. 

0 0.8 

z 

0 

tO 

« 

0:: 0.4 l.L 

i' 

4 

TIME POST INTAKE (days) 

FIGURE A.7.6 Co-60 Ingestion; Feces 

A-22 
w 

~ 

~ 2 

u.. 

0 

2 

0 

i= 

0 

« 

a:: 

u.. 

,.., -I 

0.40 

0.30 

0.20 

0.10 

o 6 

-lJJ 

~ 

~ 

z 4 

u.. 

o 

z 

o 

I- 2 

u 

<[ 

0: 

u.. 

2 3 

TIME POST INTAKE (days) 

FIGURE A.7.7 Nb-95 Ingestion; Feces 

• 

123 

TI ME POST INTAKE (days) 

FIGURE A.7.8 Cs-137 Ingestion; Feces 

A-23 

I 

4 
L\J 

x: 0.30 

~. Z 

I.&.. 

0 0.20 

t5 

i= 

(.) 

« 

D: 

I.&.. 0.10 

TI ME POST INTAKE (days) 

FIGURE A.7.10 Sr-90 Ingestion; Feces 

0.30 

0.20 

0.10 

3 4 6 

TIME POST INTAKE (days) 

FIGURE A.7.9 Ce-141 Ingestion; Feces 

A-24 
6r---.----r--~--_,----r_--~--_r--_. 

- 5 

N 

I 

0 

- 4 

l&J 

~ 

~ 2 3 

l1.. 

0 

z 2 

0 

i= 

0 

<t 

a:: 

l1.. 

TIME POST INTAKE (days) 

FIGURE A.7.ll Sr-90 Ingestion, Urine 

0.40 

UJ 0.30 ~ 

~ Z 

Lt.. 

0 0.20 

z 

0 

1-. 

0 « 

a:: 0.10 Lt.. 

TIME POST INTAKE (days) 

FIGURE A.7.l2 Ce-l44 Ingestion; Feces 

A-25 
N -

I 

0 15 -

-

Lt.J 

:::c: 

~ 2 10 

LI.. 

0 

2 

0 

I0 5 

<{ 

a:: 

LI.. 

_ 60 

..,. 

I 

o 50 

-

Lt.J 

:::c: ;:! 40 

z 

LI.. 30 

o 

z 

o 

I- 20 

o 

<{ 

e: 10 

TIME POST INTAKE (days) 

FIGURE A.7.l3 U-233 Inhalation; Urine; Class D 

• 

• • • 

3 6 9 12 

TIME POST INTAKE (days) 

FIGURE A.7014 Am-241 Inhalation; Urine; Class W 

A-26 

70 

15 
LZ-V 

(sl\oP) ~>l'1.1N I .1S0d 3W 1.1 

91 61 6 00 

." 

::u 

l> 

(") 

-f 

(5 

9 z 

0 

• ." 

Z 

;t 

" ITI 

01_ 

0 

I 

N 

-
Direct comparison of whole body counting measurements to expectation values of 

intake in the whole body are presented in Table A.7.3.The expected value of 

body burden is the product of the IRF and the best estimate of intake. The 

IRFs were obtained by using equation 2.5.1. The unweighted value of int 

was based on equation A.2.4 and the weighted value of intake was based on 

equation A.7.I. 

Table A.1.3 Verification of IKFs Using Whole-Body Counting Measurements 

Case Nuclide 

I Co-60 

I Mn-54 

Day.Post 

Intake, 

days 

1 

2 

8 

41 

80 

148 

202 

325 

667 

1025 

1370 

1751 

1 

2 

8 

41 

148 

325 

Measured 

Body 

Burden, 

Bq 

3.4E04 

3.7E04 

2.2E03 

I.9E03 

2.0E03 

I.6E03 

I.3E03 

I.OE03 

5.6E02 

I.5E02 

I.6E02 

8.9EOI 

I.OE04 

I.2E04 

2.2E02 

5.6EOI 

2.7E02 

2.IE02 

Total 

Body 

IRF 

5. 66E-OI 

4.23E-OI 

I.71E-OI 

I.08E-OI 

7.08E-02 

3.68E-02 

2.40E-02 

I.28E-02 

6.7IE-03 

4.30E-03 

2. 82E-03 

I.77E-03 

5.77E-OI 

4.96E-OI 

3.39E-OI 

1. 57E-OI 

I.94E-02 

6.lOE-04 

Unweighted 

Expectation 

Value of 

Body Burden, 

Bq 

3.7E04 

2 .. 7E04 

I.IE04 

6.7E03 

5.IE03 

2.4E03 

I.6E03 

8.3E02 

4.3E02 

2.8E02 

I.8E02 

I.2E02 

9.7E03 

8.4E03 

5.7E03 

2.7E03 

3.3E02 

I.OEOI 

Weighted 

Expectation 

Value of 

Body Burden~ 

Bq 

2.IE04 

I.6E04 

6.5E03 

4.IE03 

2.9E03 

I.4E03 

9.IE02 

4.8E02 

2.5E02 

I.6E02 

I.IE02 

6.7EOI 

9.0E 

7.8E02 

5.3E02 

2.5E02 

3.0EOI 

9.6-01 

A plot of the relative residuals, which is the squared difference between 

measured value and ~xpectation value divided by expectation value, versus 

expectation value, reveals no discernable pattern for unweighted or weighted 

data. However, the residuals are smaller for the unweighted data which 

indicates to us that the unweighted estimate of intake, equation A.2.4, is 

best suited for estimating intakes from several measurements. A plot of total 

body activity predicted by using both the weighted and unweighted estimates of 

intake is given by Figure A.7.16. It should be noted that on the average, 

measured values are closer to the unweighted expectation values. 

A-28 
45.00 ,--,..--.,--.,--..,--r--r--r---r---r----r--r--...---,,--.,--,..-..,.---, 

40.00 BEST ESTIMATE OF INTAKE • 6.5 E4 Bq " 

cr 

CD 35.00 

.,: 

o 0_30.00 

CD(/) 

.,JO 

i::!"~ 25.00 

O(/) 

t-=> 

zO 20.00 _J: 

)-tt- - 15.00 

:;: 

~ 10.00 

0.00 I 

o 

c MEASURED VALUES 

+ UNWEIGHTED 

- WEIGHTED 

16 40 100" 251 631 1585 

TIME POST INTAKE, DAYS 

FIGURE A. 7.16 Calculated and Measured Values of Total "Body 

Activity Following Inhalation of Class W Co-60. 

A-29 
8. BIBLIOGRAPllY 

ANSI86 

AHIPHATF86 

ICRP74 

Li85 

Li86 

American National Standards Institute, Health Physics Socie 

Subcommittee WG 2.5, 1986, ANSI 13.30, "Draft Performance 

Criteria for Radiobioassay". 

Ad Hoc Interagency Public Health Assessment Task Force, 1986, 

Assessment of the Public Health Impact from the Accidental 

Release of UFg at the Sequoyah Fuels Corporation Facility at 

Gore, Oklahoma, U.S. Nuclear Regulatory Commission Report, 

NUREG 1189, Washington, D.C. 

International Commission on Radiological Protection, 1974, 

Reference.Man, ICRP Publication 23, (New York: Pergamon Press). 

~ paper on this accident was published in Anais do Primeiro 

Congresso Brasileiro de Energia Nuclear, Rio de Janeiro, 1986 

and in summary in the Brazilian'journal Ciencia e Cultura, Vol. 

37, No.7, 1985. Measurements we~e performed by Joyce L. 

Lipsztein, Janete C. Gaburo, aan Carlos H. Mesquita from 

Comissao Nacional de Energia Nuclear Brazil. 

Patient results for this example were obtained by Joyce L. 

Lipsztein, Janete C. Gaburo, C. H. Mesquita and M. O. 

from Comissao Nacional de Energia Nuclear Brasil. They 

presented in the First Meeting of the Brazilian Atomic 

Association in Ri.o de Janeiro, 1986, and were accepted for 

publication in summary form at the journal Ciencia e Cultura. 

A-30 
. ' , -, .' 

APPENDIX B 

TABULATED DATA 

1. INTRODUCTION 

In order to use the following pages, information regarding their structure 

is necessary. Therefore, we note the following details. The intake retention 

fractions, IREs, for a particular in vivo or in vitro bioassay compartment of 

interest are tabulated for various times. They are applicable for single 

inhalation intakes, see tables in Sections 2 through 4, and single ingestion 

intakes, see tables in Section 5. The IREs include the decay factor radionuclides. The element name, the mass number, the halflife, lung-clearance 

classification, and particle size are printed at the beginning of each table. 

If the excretion pathway has been defined, the IREs for urine and feces are 

given, otherwise the IREs for systemic excreta and non-systemic excreta are 

given. All values of IREs have three significant figures and are expressed in 

exponential notation; for example, 3.78E-02 is 0.0378. The time post intake is 

given in units of days and IREs are listed if they are greater than 1.00E-08, 

otherwise O.OOE+OO is inserted into the table. In order to facilitate locating 

the table of interest, a page listing by atomic number is given in Section 1.1 

for Class D inhalation, Section 1.2 for Class W inhalation, Section 1.3 for 

Class Y inhalation and Section 1.4 for ingestion. The page listing for 

biological and radiological parameters is given in Section 1.5. In the case of 

1-131, 1-132 and 1-133, additional tables of IRFs for the thyroid are given for 

inhalation and ingestion intakes. In the case of C-14 monoxide, C-14 dioxide 

and tritiated water, tables of IREs are listed separately in Section 6. The 

biological and radiological parameters which were used as input for development 

of IRE tables are presented in Section 7. In certain circumstances, one may 

need to transform the IRE for use with a different particle size, and guidance 

is given in Section 8. In some instances, one may need to interpret measurements following protracted intakes, and guidance is given in Section 9. A 

bibliography is included in Section 10. Finally, an alphabetical index, which 

is based on element name, is given in Section 11 in order to facilitate access 

to the in vivo or in vitro intake retention fraction of interest • 

B-1 
1.1 Class D Tables Listed by Atomic Number 

ATOMIC NUMBER 

9 

11 

12. 

13 

14 

15 

16 

17 

19 

22 

23 

24 

25 

26 

28 

29 

31 

32 

34 

35 

37 

38 

40 

42 

43 

44 

46 

47 

48 

49 

50 

ELEMENT 

Fluorine •••••••••••••••••••••••••••••• 

Sodium •••••••••••••••••••••••••••••••• 

Magnesium ••••••••••••••••••••••••••••• 

Aluminum •••••••••••••••••••••••• " ••••• • 

Sillcon ••••••••••••••••••••••• ~ ••••••• 

Phosphorus •••••••••••••••••••••••••••• 

Sulphur ••••••••••••••••••••••••••••••• 

Chlorine •••••••••••••••••••••••••••••• 

Potassium ••••••••••••••••••••••••••••• 

Titanium •••.••••••••••••••••.••••••••••• 

Vanadium •••••••••••••••••••••••••••••• 

Chromium •••••••••••••••••••••••••••••• 

Manganese ••••••••••••••••••••••••••••• 

Iron •••••••••••••••••••••••••••••••••• 

Nickel •••••••••••••••••••••••••••••••• 

Copper •••••••••••••••••••••••••••••••• 

Gallium ••••••••••••••••••••••••••••••• 

Germanium ••••••••••••••••••••••••••••• 

Selenium •••••••••••••••••••••••••••••• 

Bro.ine ••••••••••••••••••••••••••••••• 

Rubidium •••••••••••••••••••••••••••••• 

Strontium ••••••••••••••••••••••••••••• 

Zirconium ••••••••••••••••••••••••••••• 

Molybdenum •••••••••••••••••••••••••••• 

Technetium •••••••••••••••••••••••••••• 

Ruthenium ••••••••••••••••••••••••••••• 

Palladium ••••••••••••••••••••••••••••• 

Silver •••••••••••• ' •••••••••••••••••••• 

Cadmium ••••••••••••••••••••••••••••••• 

Indium •••••••••••••••••••••••••••••••• 

Tin ••••••••••••••••••••••••••••••••••• 

B-2 

PAGE 

B-13 

B-14 

B-16 

8-18 

B-20 

B-22 

B~26 

B-30 

B-34 

B-38 

B-40 

B-42 

B-46 

B-50 

B-56 

B-58 

B-60 

B-62 

B-64 

B-66 

B-70 

B-72 

B-78 

B-80 

B-82 

B-84 

B-86 

B-88 

8-90 

B-92 

B-93 
ATOMIC NUMBER ELEMENT PAGE 

-

52 Tellurium ••••••••••••••••••••••••••••• B-95 

53 Iodine ••••• ~ •••••••••••••••••••••••••• B-97 

55 Cesium •••••••••••••••••••••••••••••••• B-I09 

56 Barium •••••••••••••••••••••••••••••••• B-1 13 

57 Lanthanum ••••••••••••••••••••••••••••• B-II7 

64 Gadolinium •••••••••••••••••••••••••••• B-121 

72 Hafnium ••••••••••••••••••••••••••••••• B-123 

74 TUngsten •••••••••••••••••••••••••••••• B-I27 

75 Rhenium ••••••••••••••••••••••••••••••• B-129 

76 Osmium •••••••••••••••••••••••••••••••• B-13l 

77 Iridium •••••••••••••••••••••••••••••.•• B-I33 

78 Platinum •••••••••••••••••••••••••••••• B-I37 

79 Gold •••••••••••••••••••••••••••••••••• B-139 

80 Mercury ••••••••••••••••••••••••••••••• B-141 

81 Thallium •••••••••••••••••••••••••••••• B-143 

82 Lead •••••••••••••••••••••••••••••••••• B-147 

83 Bismuth ••••••••••••••••••••••••••••••• B-I49 

84 Polonium •••••••••••••••••••••••••••••• B-151 

85 Astatine •• ~ ••••••••••••••••••••••••••• B-I53 

87 Francium •••••••••••••••••••••••••••••• B-IS5 

89 Actinium •••••••••••••••••••••••••••••• B-lS6 

92 Uranium ••••••••••••••••••••••••••••••• B-lS8 

B-3 
,'.': 

1.2 Class W Tables Listed by Atomic Number 

ATOMIC NUMBER ELEMENT 

4 

9 

12 

13 

14 

15 

16 

17 

20 

22 

23 

24 

25 

26 

27 

28 

29 

31 

33 

34 

35 

39 

40 

41 

43 

44 

45 

46 

47 

48 

49 

Beryllium ••••••••••••••••••••••••••••• 

Fluorine •••••••••••••••••••••••••••••• 

Magnesium ••••••••••••••••••••••••••••• 

Aluudnum •••••••••••••••••••••••••••••• 

Silicon ••••••••••••••••••••••••••••••• 

Phosphorus •••••••••••••••••••••••••••• 

Sulphur ••••••••••••••••••••••••••••••• 

Chlorine •••••••••••••••••••••••••••••• 

Calcium ••••••••••••••••••••••••••••••• 

Titanium •••••••••••••••••••••••••••••• 

Vanadium •••••••••••••••••••••••••••••• 

Chromium •••••••••••••••••••••••••••••• 

Manganese ••••••••••••••••••••••••••••• 

Iron •••••••••••••••••••••••••••••••••• 

Cobalt •••••••••••••••••••••••••••••••• 

Nickel •••••••••••••••••••••••••••••••• 

Copper •••••••••••••••••••••••••••••••• 

Gallium ••••••••••••••••••••••••••••••• 

Arsenic ••••••••••••••••••••••••••••••• 

Selenium •••••••••••••••••••••••••••••• 

Bromine ••••••••••••••••••••••••••••••• 

yttrium ••••••••••••••••••••••••••••••• 

Zirconium ••••••••••••••••••••••••••••• 

Niobium ••••••••••••••••••••••••••••••• 

Technetium •••••••••••••••••••••••••••• 

Ruthenium ••••••••••••••••••••••••••••• 

Rhodium ••••••••••••••••••••••••••••••• 

Palladium ••••••••••••••••••••••••••••• 

Silver •••••••••••••••••••••••••••••••• 

Cadmium ••••••••••••••••••••••••••••••• 

Indium •••••••••••••••••••••••••••••••• 

B-4 

PAGE 

B-165 

B-167 

B-168 

B-170 

B-172 

B-174 

B-178 

B-182 

B-186 

B-192 

B-194 

B-196 

B-200 

B-204 

B-208 

B-214 

B-216 

B-218 

B-220 

B-222 

B-224 

B-228 

B-232 

B-234 

B-238 

B-240 

B-242 

B-244 

B-246 

B-248 

B-250 
ATOMIC NUMBER 

50 

52 

57 

58 

59 

60 

61 

62 

63 

64 

65 

66 

67 

68 

69 

70 

71 

72 

73 

75 

77 

79 

83 

84 

85 

88 

89 

90 

91 

92 

93 

94 

95 

96 

ELEMENT 

Tin ••••••••••••••••••••••••••••••••••• 

Tellurium ••••••••••••••••••••••••••••• 

Lanthanum ••••••••••••••••••••••••••••• 

Cerium •••••••••••••••••••••••••••••••• 

Praseodymium •••••••••••••••••••••••••• 

Neod~um ••••••••••••••••••••••••••••• 

Promethium •••••••••••••••••••••••••••• 

Samarium •••••••••••••••••••••••••••••• 

Europium •••••••••••••••••••••••••••••• 

Gadolinium •••••••••••••••••••••••••••• 

Terbium ••••••••••••••••••••••••••••••• 

Dysprosium •••••••••••••••••••••••••••• 

Holmium ••••••••••••••••••••••••••••••• 

Erbium ••••••••.•••••••••••••••••••••••• 

Thulium ••••••••••••••••••••••••••••••• 

ytterbium ••••••••••••••••••••••••••••• 

Lutetium •••••••••••••••••••••••••••••• 

Hafnium ••••••••••••••••••••••••••••••• 

Tantalum •••••••••••••••••••••••••••••• 

Rhenium •••••••••••••••••••••••• e .•••••• 

Iridium ••••••••••••••••••••••••••••••• 

Gold •••••••••••••••••••••••••••••••••• 

Bismuth ••••••••••••••••••••••••••••••• 

Polonium •••••••••••••••••••••••••••••• 

Astatine •••••••••••••••••••••••••••••• 

Radium •••••••••••••••••••••••••••••••• 

Actinium •••• • ' ••••••••••••••••••••••••• 

Thorium ••••••••••••••••••••••••••••••• 

Protactinium •••••••••••••••••••••••••• 

Uranium ••••••••••••••••••••••••••••••• 

Neptunium ••••••••••••••••••••••••••••• 

Plutonium ••••••••••••••••••••••••••••• 

Americium ••••••••••••••••••••••••••••• 

Curium •••••••••••••••••••••••••••••••• 

B-5 

PA\:ir.. 

B-251 

B-253 

B-255 

B-259 

B-265 

B-267 

B-269 

B-271 

B-275 

B-281 

B-283 

B-285 

B-287 

B-289 

B-291 

B-293 

B-295 

B-297 

B-301 

B-305 

B-309 

B-313 

B-315 

B-317 

B-319 

B-321 

B-325 

B-327 

B-335 

B-337 

B-343 

B-345 

B-353 

B-357 
' .. 

1.3 Class Y Tables Listed by Atomic Number 

ATOMIC NUMBER ELEMENT 

4 

9 

14 

21 

22 

24 

27 

29 

30 

38 

39 

40 

41 

42 

44 

45 

46 

47 

48 

58 

59 

60 

61 

70 

71 

73 

76 

n 

79 

89 

90 

91 

92 

94 

9S 

Beryllium ••••••••••••••••••••••••••••• 

Fluorine •••••••••••••••••••••••••••••• 

Silicon ••••••••••••••••••••••••••••••• 

Scandium ••••••••••••••••••••••••••••• 

Titanium •••••••••••••••••••••••••••••• 

Chromium •••••••••••••••••••••••••••••• 

Cobalt •••••••••••••••••••••••••••••••• 

Copper •••••••••••••••••••••••••••••••• 

~inc •••••••••••••••••••••••••••••••••• 

Strontium ••••••••••••••••••••••••••••• 

yttrium ••••••••••••••••••••••••••••••• 

Zirconium ••••••••••••••••••••••••••••• 

Niobium ••••••••••••••••••••••••••••••• 

MOlybdenum •••••••••••••••••••••••••••• 

Ruthenium ••••••••••••••••••••••••••••• 

Rhodium ••••••••••••••••••••••••••••••• 

Palladium ••••••••••••••••••••••• ' •••••• 

Silver •••••••••••••••••••••••••••••••• 

Cadmium ••••••••••••••••••••••••••••••• 

Cerium •••••••••••••••••••••••••••••••• 

Praseodymium •••••••••••••••••••••••••• 

Neodymium ••••••••••••••••••••••••••••• 

Promethium •••••••••••• • -••••••••••••••• 

ytterbium ••••••••••••••••••••••••••••• 

Lutetium ................. " • ••••••••••••• 

Tantalum •••••••••••••••••••••••••••••• 

Osmium •••••••••••••••••••••••••••••••• 

Iridium ••••••••••••••••••••••••••••••• 

Gold •••••••••••••••••••••••• " •••••••••• 

Actinium ••••••••••••••••••••••••••••• 

Thorium ••••••••••••••••••••••••••••••• 

Protactinium •••••••••••••••••••••••••• 

Uranium ••••••••••••••••••••••••••••••• 

Plutonium ••••••••••••••••••••••••••••• 

Americium ••••••••••••••••••••••••••••• 

B-6 

PAGE 

B-360 

B-362 

B-363 

B-365 

B-367 

B-369 

B-373 

B-379 

B-381 

B-385 

B-391 

B-393 

B-395 

B-399 

B-401 

B-403 

B-405 

B-407 

B-409 

B-411 

B-417 

B-419 

B-421 

B-423 

B-425 

B-427 

B-431 

B-433 

B-437 

B-439 

B-441 

B-449 

B-451 

B-455 

B-463 
1.4 Insestion Tables Listed by Atomic Number 

ATOMIC NUMBER ELEMENT PAGE 

4 Beryllium ••••••••••••••••••••••••••••• B-468 

9 Fluorine ••• _ ••••••••••••••••••••••••••• B-472 

11 Sodium •••••••••••••••••••••••••• •.••••• B-473 

12 Magnesium ••••••••••••••••••••••••••••• B-475 

13 Aluminum •••••••••••••••••••••••••••••• B-477 

14 Silicon •••••••••• ~ •••••••••••••••••••• B-479 

15 Phosphorus •••••••••••••••••••••••••••• B-481 

16 Sulphur ••••••••••••••••••••••••••••••• B-485 

17 Chlorine •••••••••••••••••••••••••••••• B-489 

19 Potassium ••••••••••••••••••••••••••••• B-493 

20 Calcium ••••••••••••••••••••••••••• a_a •• B-497 

22 Titanium •••••••••••••••••••••••••••••• B-503 

23 Vanadium •••••••••••••••••••••••••••••• B-505 

24 Chromium •••••••••••••••••••••••••••••• B-507 

25 Manganese., •••••• ~ ••••••••••••••••••••• B-511 

26 Iron •••••••••••••••••••••••••••••••••• :&-515 

27 Cobalt •••••••••••••••••••••••••••••••• B-521 

28 Nickel •••••••••••••••••••••••••••••••• B-527 

29 Copper •••••••••••••••••••••••••••••••• B-529 

30 Zinc •••••••••••••••••••••••••••••••••• B-531 

31 Gallium ••••••••••••••••••••••••••••••• B-535 

32 Germanium ••••••••••••••••••••••••••••• B-537 

33 Arsenic ••••••••••••••••••••••••••••••• B-539 

34 Selenium •••••••••••••••••••••••••••••• B-541 

35 Bromine ••••••••••••••••••••••••••••••• B-543 

37 Rubidium •••••••••••••••••••••••••••••• B-547 

38 Strontium ••••••••••••••••••••••••••••• B-549 

":';"< 39 yttrium ••••••••••••••••••••••••••••••• B-555 

40 Zirconium ••••••••••••••••••••••••••••• B-557 

41 Niobium ••••••••••••••••••••••••••••••• B-559 

42 Molybdenum •••••••••••••••••••••••••••• B-563 

43 Technetium •••••••••••••••••••••••••••• B-565 

44 Ruthenium ••••••••••••••••••••••••••••• B-567 

45 Rhodium ••••••••••••••••••••••••••••••• B-569 

46 Palladium ••••••••••••••••••••••••••••• B-571 

B-7 
ATOMIC NUMBER 

47 

48 

50 

52 

53 

55 

56 

57 

58 

59 

60 

61 

62 

63 

64 

65 

66 

67 

68 

70 

71 

72 

73 

74 

75 

77 

78 

79 

80 

" 81 

82 

84 

88 

89 

90 

91 

92 

93 

94 

95 

96 

ELEMENT 

Silver •••.•••••.•• . ' ••••.••..•••.•••••• 

Cadmium ••••••••••••••••••••••••••••••• 

Tin ••••••••••••••••••••••••••••••••••• 

Tellurium ••••••••.••• a'a ••••••••••••••• 

Iodine •••••••••••••••••••••••••••••••• 

Cesium ••••••••••••••••••••••••••••••• 

Barium •••••••••••••••••••••••••••••••• 

Lanthanum ••••••••••••••••••••••••••••• 

Cerium •••••••••••••••••••••••••••••••• 

Praseodymium •••••••••••••••••••••••••• 

Neodymium ••••••••••••••••••••••••••••• 

Promethium •••••••••••••••••• •.••••••••• 

Sama.rlum ••••••••••••••••••••••••• a· •••• 

Europium •••••••••••••••••••••••••••••• 

Gadolinium •••••••••••••••••••••••••••• 

Terbium ••••••••••••••••••••••••••••••• 

Dysprosium •••••••••••••••••••••••••••• 

Holmium ••••••••••••••••••••••••••••••• 

Erbium •••••••••••••••••••••••••••••••• 

Ytterbium ••••••••••• ~ ••••••••••••••••• 

Lutetium •••••••••••••••••••••••••••••• 

llafnium ••••••••••••••••••••••••••••••• 

Tantalum ••••••• ~ •••••••••••••••••••••• 

Tungsten •••••••••••••••••••••••••••••• 

Rhenium ••••••••••••••••••••••••••••••• 

Iridium ••••••••••••••••••••••••••••••• 

Platinum •••••••••••••••••••••••••••••• 

Gold •••••••••••••••••••••••••••••••••• 

Mercury ••••••••••••••••••••••••••••••• 

Thallium •••••••••••••••••••••••••••••• 

Lead •••••••••••••••••••••••••••••••••• 

Polonium •••••••••••••••••••••••••••••• 

Ra.dium •••••••••••••••••••••••••••••••• 

Actinium' •••••••••••••••••••••••••••••• 

Thorium ••••••••••••••••••••••••••••••• 

Protactinium •••••••••••••••••••••••••• 

Uranium ••••••••••••••••••••••••••••••• 

Neptunium ••••••••••••••••••••••••••••• 

Plutonium ••••••••••••••••••••••••••••• 

Americium ••••••••••••••••••••••••••••• 

Curium •••••••••••••••••••••••••••••••• 

B-8 

PAGE 

B-573 

B-575 

B-577 

B-579 

B-581 

B-590 

B-594 

B-598 

B-602 

B-608 

B-610 

B-612 

B-614 

B-618 

B-624 

B-626 

B-628 

B-630 

B-632 

B-634 

B-636 

B-638 

B-642 

B-646 

B-648 

B-652 

B-656 

B-658 

B-660 

B-662 

B-666 

B-668 

B-670 

B-674 

B-676 

B-684 

B-686 

B-692 

B-694 

B-702 

B-704 
1.5 Biological and Radiolosical Parameters Listed by Atomic Number 

ATOMIC NUMBER ELEMENT PAGE 

1 Hydrogen •••••••••••••••••••••••••••••• B-713 I 4 Beryllium ••••••••••••••••••••••••••••• B-714 

6 Carbon •••••••••••••••••••••••••••••••• B-715 

9 Fluorine •••••••••••••••••••••••••••••• B-717 

11 Sodium •••••••••••••••••••••••••••••••• B-718 

12 Magnesium ••••••••••••••••••••••••••••• B-719 

13 .Aluminum •••••••••••••••••••• " •••••••••• B-720 

14 Silicon •••••••••••••••••••••• ~ •••••••• B-721 

15 Phosphorus •••••••••••••••••••••••••••• B-722 

16 Sulphur ••••••••••••••••••••••••••••••• B-723 

17 Chlorine •••••••••••••••••••••••••••••• B-724 

19 Potassium ••••••••••••••••••••••••••••• B-725 

20 Calcium •••••••••••••••••• e"e ••••••••••• B-726 

21 Scandium •••••••••••••••••••••••••••••• B-727 

22 Titanium •••••••••••••••••••••••••••••• B-728 

23 Vanadium •••••••••••••••••••••••••••••• B-729 

24 Chromium •••••••••••••••••••••••••••••• B-730 

25 Manganese ••••••••••••••••••••••••••••• B-731 

26 Iron •••••••••••••••••••••••••••••••••• .B-732 

27 Cobalt •••••••••••••••••••••••••••••••• B-733 

28 Nickel •••••••••••••••••••••••••••••••• B-734 

29 Copper •••••••••••••••••••••••••••••••• B-735 

30 Zinc •••••••••••••••••••••••••••••••••• B-736 

31 Gallium ••••••••••••••••••••••••••••••• B-737 

32 Germanium ••••.••••••••••••••••••••••••• B-738 

33 Arsenic ••••••••••••••••••••••••••••••• B-739 »--' 

34 Selenium •••••••••••••••••••••••••••••• B-740 

35 Bromine ••••••••••••••• ~ ••••••••••••••• B-741 

37 RUbidiu ••••••••••••••••••••••••••••••• B-742 

38 Strontium ••••••••••••••••••••••••••••• B-743 

39 yttrium ••••••••••••••••••••••••••••••• B-744 

40 Zirconium ••••••••••••••••••••••••••••• B-745 

B-9 
ATOMIC NUMBER 

41 

42 

43 

44 

45 

46 

47 

48 

49 

50 

51 

52 

53 

55 

56 

57 

58 

59 

. 60 

61 

62 

63 

64 

65 

66 

67 

68 

69 

70 

71 

72 

73 

74 

75 

ELEMENT 

Nlobium •••••••••••••• ~ •••••••••••••••• 

Molybdenum ••••••••••••••••• " ••••••••••• 

Technetium •••••••••••••••••••••••••••• 

Ruthenium ••••••••••••••••••••••••••••• 

Rhodium ••••••••••••••••••••••••••••••• 

Palladium ••••••••••••••••••••••••••••• 

Silver •••••••••••••••••••••••••••••••• 

Cadmium ••••••••••••••••••••••••••••••• 

Inqium •••••••••••••••••••••••••••••••• 

Tin ••••••••••••••••••••••••••••••••••• 

Antimony •••••••••••••••••••••••••••••• 

Tellurium ••••••••••••••••••••••••••••• 

Iodine •••••••••••••••••••••••••••••••• 

Cesium •••••••••••••••••••••••••••••••• 

Barium •••••••••••••••••••••••••••••••• 

·Lanthanum ••••••••••••••••••••••••••••• 

Cerium •••••••••••••••••••••••••••••••• 

Praseodymium •••••••••••••••••••••••••• 

Neodymium ••••••••••••••••••••••••••••• 

Promethium •••••••••••••••••••••••••••• 

Samarium •••••••••••••••••••••••••••••• 

Europium •••••••••••••••••••••••••••••• 

Gadolinium •••••••••••••••••••••••••••• 

Terbium ••••••••••••••••••••••••••••••• 

Dysprosium •••••••••••••••••••••••••••• 

Holmium ••••••••••••••••••••••••••••••• 

Erbium •••••••••••••••••••••••••••••••• 

Thulium." •••••••••••••••••••••••••••••• 

ytterbium ••••••••••••••••••••••••••••• 

Lutetium •••••••••••••••••••••••••••••• 

Hafnium ••••••••••••••••••••••••••••••• 

Tantalum •••• · •••••••••••••••••••••••••• 

Tungsten •••••••••••••••••••••••••••••• 

Rhenium ••••••••••••••••••••••••••••••• 

B-I0 

PAGE 

B-746 

B-747 

B-748 

B-749 

B-750 

B-751 

B-752 

B-753 

B-754 

B-755 

B-756 

B-757 

B-758 

B-759 

B-760 

B-761 

B-762 

B-763 

B-764 

B-765 

B-766 

B-767 

B-768 

B-769 

B-770 

B-771 

B-772 

B-773 

B-774 

B-775 

B-776 

B-777 

B-778 

B-779 
ATOMIC NUMBER ELEMENT PAGE 

76 Osmium ••••••••••••••••••••••••••••.•• •• B-780 

77 Iridium ••••••••••••••••••••••••••••••• B-781 

78 Platinum •••••••••••••••••••••••••••••• B-782 I 79 Gold •••••••••••••••••••••••••••••••••• B-783 

80 Mercury ••••••••••• •.•••••••••••• e .•••••• B-784 

81 Thallium •••••••••••••••••••••••••••••• B-785 

82 Lead •••••••••••••••••••••••••••••••••.• B-786 

83 Bismuth •••••••••••••••••• e .•••.••••••••• B-787 

84 Polonium •••••••••••••••••••••••••••••• B-788 

85 Astatine •••••••••••••••••••••••••••••• B-789 

87 Francium •••••••••••••••••••••••••••••• B-790 

88 Radium •••••••••••••••••••••••••••••••• B-791 

89 Actinium •••••••••••••••••••••••••••••• B-792 

90 Thorium ••••••••••••••••••••••••••••••• B-793 

91 Protactinium •••••••••••••••••••••••••• B-794 

92 Uranium ••••••••••••••••••••••••••••••• B-795 

93 Neptunium ••••••••••••••••••••••••••••• B-796 

94 Plutonium ••••••••••••••••••••••••••••• B-797 

95 Americium ••••••••••••••••••••••••••••• B-798 

96 Curium •••••••••••••••••••••••••••••••• B-799 

B-ll 

zt-II 

S'lOSODY a SSY'J:) .10 

ROID'IYBRI 3'lfJlIIS 1IOa SROIl:mLi ROUllCJXlI ORY ROIl.D.l.3.I: ao S1I'l8'Y.I. ·z 
CLASS D AHA.D - 1 HICKOK STABLE PWORINE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1'.O:OE-OI 3. 91E-Ol 2. 26E-Ol 3.03E-04 2. 17E-02 6. 39E-Ol 

2.00E-01 4.36E-01 2.01E-01 2. 96E-07 2. 28E-03 6. 39E-01 

3.00E-01 4. 59E-01 1.79E-01 O .. OOE+OO 4. 15E-04 6. 39E-01 

4.00E-01 4.79E-01 1.6(,"'-01 O.OOE+OO 1. 85E-04 6. 39E-Ol 

5.00E-01 4.96E-01 1.43E-01 O.OOE+OO 1.21E':"04 6. 39E-01 

6.00E-01 5. 12E-01 1.27E-01 O.OOE+OO 8. 47E-05 6. 39E-01 

7.00E-01 5. 26E-Ol 1. 13E-Ol O.OOE+OO 5. 98E-05 6. 39E-01 

8.00E-01 5. 38E-01 1.01E-01 O.OOE+OO 4. 23E-05 6. 39E-01 

9.00E-01 5.50E-01 8. 96E-02 O.OOE+OO 2. 99E-05 6. 39E-01 

1.00E+00 5.59E-01 7. 97E-02 O.OOE+OO 2. 12E-05 6. 39E-01 

2.00E+00 6. 15E-01 2. 42E-02 O.OOE+OO 7.04E-07 6. 39E-Ol 

3.00E+00 6. 32E-01 7. 13E-03 O.OOE+OO 3. 82E-08 6. 39E-01 

4.00E+00 6. 37E-01 2.05E-03 O.OOE+OO O.OOE+OO 6. 39E-01 

5.00E+00 6.39E-01 5. 81E-04 O.OOE+OO O.OOE+OO 6. 39E-01 

6.00E+00 6.39E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO 6. 39E-01 

7.00E+00 6. 39E-01 4. 47E-05 O.OOE+OO O.OOE+OO 6. 39E-01 

8.00E+00 6. 39E-01 1. 22E-05 O.OOE+OO O.OOE+OO 6. 39E-01 

9.00E+00 6.39E-01 3. 32E-06 O.OOE+OO O.OOE+OO 6.39E-01 

1.00E+01 6.39E-01 8.96E-07 O.OOE+OO O.OOE+OO 6. 39E-Ol 

2.00E+Ol 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

3.00E+01 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

4.00E+Ol 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

5.00E+Ol 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

6.ooE+Ol 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

7.00E+Ol 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

8.00E+Ol 6 .. 39E-01 O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

9.00E+01 6. 39E-Ol O.OOE+OO O.ooE+OO' O.OOE+OO 6. 39E-Ol 

1.00E+02 6.39E-01 O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

2.00E+02 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

3.00E+02 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

4.00E+02 6.39E-01 O.OOE+OO O.OOE+OO O.OOE+oo 6. 39E-01 

5.00E+02 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

6.00E+02 6. 39E-01 O.OOE+OO O.OOE+OO O.OOE+oo 6. 39E-Ol 

7.ooE+02 6. 39E-01 O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

8.00E+02 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-01 

9.00E+02 6.39E-01 O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol " " 

.:-. 1.00E+03 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

2.00E+03 6.39E-01 O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

4.00E+03 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

8.00E+03 6.39E-Ol O.OOE+OO O.ooE+OO O.OOE+OO 6. 39E-Ol 

1.00E+04 6. 39E-01 O.OOE+oo O.OOE+OO O.OOE+oo 6. 39E-01 

2.00E+04 6.39E-Ol O.OOE+OO O.ooE+OO O.OOE+OO 6. 39E-01 

8-13 
CLASS D AHAD- 1 HICRON STABLE SODIUM 23 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE· --------------------------------------------------------

SYSTEMIC NASAL 01 TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.B9E-OI 2. 26E-OI 3.03E-04 2.17E-02 6. 37E-OI 

2.00E-OI 4.3IE-OI 2.0IE-OI 2. 96E-07 2. 28E-03 6. 34E-OI 

3.00E-OI 4.SIE-0l I. 79E-OI O.OOE+OO 4.ISE-04 6.3IE-0l 

4.00E-OI 4. 68E-0l 1.60E-OI O.OOE+OO I. BSE-04 6. 28E-OI 

S.OOE-OI 4. 82E-OI I. 43E-OI O.OOE+OO l.2IE-04 6.2SE-OI 

6.00E-Ol 4. 94E-OI I. 27E-OI O.OOE+OO 8. 47E-OS 6.2IE-OI 

7.00E-Ol S.OSE-Ot 1.13E-0l O.OOE+OO S.9BE-OS 6.18E-OI 

8. OOE-O 1 S.14E-OI I.OIE-OI O.OOE+OO 4. 23E-OS 6.14E-OI 

9.00E-OI S.2IE-0l 8. 96E-02 O.OOE+OO 2.99E-OS 6.l1E-0l 

I.OOE+OO S.28E-OI 7. 97E-02 O.OOE+OO 2.12E-OS 6.07E-OI 

2.00E+OO S~46E-OI 2. 42E-02 O.OOE+OO 7.04E-07 S.70E-OI 

3.00E+OO S.26E-OI 7. 13E-03 O.OOE+OO 3.B2E-OB S.33E-OI 

4.00E+OO 4.9SE-OI 2.0SE-03 O.OOE+OO O.OOE+OO 4. 97E-OI 

S.OOE+OO 4. 64E-Ol S.8IE-04 O.OOE+.oO O.OOE+OO 4. 64E-OI 

6.00E+OO 4. 33E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO 4.33E-OI 

7.00E+OO 4.04E-OI 4. 47E-OS O.OOE+OO O.OOE+OO 4.04E-OI 

B.OOE+OO 3.7BE-OI I. 22E-OS O.OOE+OO O.OOE+OO 3. 78E-OI 

9.00E+OO 3.S2E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 3.S2E-OI 

I.OOE+Ol 3. 29E-OI B.96E-07 O.OOE+OO O.OOE+OO 3. 29E-OI 

2.00E+Ol 1.6SE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.6SE-OI 

3.00E+OI 8.361-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 36E-02 

4.00E+Ol 4. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-02 

S.OOE+OI 2. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 22E-02 

6.00E+OI l.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-02 

7.00E+Ol 6.B6E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.86E-03 

B.OOE+OI 4.27E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.27E-03 

9.00E+OI 2. 97E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.97E-03 

I.OOE+02 2.3IE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.31E-03 

2.00E+02 I.4SE-03 O.OOE+OO O.OOE+OO O.OOE+OO I.4SE-03 

3.00E+02 I.27E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 27E-03 

4.00E+02 1.IOE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.IOE-03 

S.OOE+02 9.S9E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.S9E-04 

6.00E+02 8.3SE-04 O.OOE+OO O.OOE+OO O.OOE+OO 8.3SE-04 

7.00E+02 7. 27E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7. 27E-04 

8.00E+02 ·6.33E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6. 33E-04 

9.00E+02 S.SlE-04 O.OOE+OO O.OOE+OO O.OOE+OO S.SlE-04 

1.00E+03 4. BOE-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. BOE-04 

2.00E+03 1.20E-04 O.OOE+OO O.OOE+OO O.OOE+OO l.20E-04 

3.00E+03 3.00E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.00E-OS 

4.00E+03 7.S0E-06 O.OOE+OO O.OOE+OO O.OOE+OO 7.S0E-06 

S.OOE+03 I.B7E-06 O.OOE+OO O.OOE+OO O.OOE+OO l.B7E-06 

6.00E+03 4. 63E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-07 

7.00E+03 1.IOE-07 O.OOE+OO O.OOE+OO O.OOE+OO 1.IOE-07 

8.00E+03 2. 13E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2. 13E-08 

B-14 
CLASS D AHAD - 1 KICRON STABLE SODIUM 23 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1. 99E-03 1. 99E-05 

2.00E-Ol 4. 85E-03 4. 85E-05 

3.00E-Ol 7.90E-03 7.90E-05 

4.00E-Ol 1. 11E-02 1. 11E-04 

5.00E-01 1. 44E-02 1. 44E-04 

6.00E-Ol 1.77E-02 1.77E-04 

7.00E-Ol 2. 12E-02 2. 12E-04 

8.00E-Ol 2. 47E-02 2. 47E-04 

9.00E-Ol 2.83E-02· 2. 83E-04 

1.00E+00 3. 19E-02 3. 19E-02 3. 19E-04 3. 19E-04 

2.00E+00 3. 74E-02 6. 93E-02 3. 74E-04 6. 93E-04 

3.00E+00 3.71E-02 1.06E-Ol 3. 71E-04 1.06E-03 

4.00E+00 3. 53E-02 1.42E-Ol 3. 53E-04 1. 42E-03 

5.00E+00 3. 31E-02 1. 75E-01 3. 31E-04 1. 75E-03 

6.00E+00 3.09E-02 2.06E-Ol 3.09E-04 2.06E-03 

7.00E+00 2. 89E-02 2. 35E-Ol 2. 89E-04 2.35E-03 

8.00E+00 2.70E-02 2. 62E-Ol 2.70E-04 2. 62E-03 

9.00E+00 2. 52E-02 2. 87E-Ol 2. 52E-04 2. 87E-03 

1.00E+Ol 2. 35E-02 3.IOE-01 2.35E-04 3.IOE-03 

2.00E+Ol 1. 17E-02 4. 74E-Ol 1. 17E-04 4. 74E-03 

3.00E+Ol 5. 87E-03 5. 56E-Ol 5. 87E-05 5. 56E-03 

4.00E+Ol 2. 94E-03 5. 96E-Ol 2. 94E-05 5. 96E-03 

5.00E+Ol 1. 47E-03 6. 17E-Ol 1. 47E-05 6. 17E-03 

6.00E+Ol 7. 36E-04 6. 27E-Ol 7. 36E-06 6. 27E-03 

7.00E+Ol 3. 69E-04 6. 32E-Ol 3. 69E-06 6. 32E-03 

8.00E+Ol 1. 86E-04 6. 35E-01 1.86E-06 6. 35E-03 

9.00E+Ol 9. 41E-05 6. 36E-01 9.41E-07 6. 36E-03 

1.00E+02 4. 82E-05 6. 37E-Ol 4. 82E-07 6.37E-03 

2.00E+02 2.06E-06 6. 38E-Ol 2.06E-08 6. 38E-03 

3.00E+02 1. 76E-06 6. 38E-Ol 1.76E-08 . 6. 38E-03 

4.00E+02 1. 53E-06 6. 38E-Ol 1. 53E-08 6. 38E-03 

5.00E+02 1. 33E-06 6. 38E-Ol 1. 33E-08 6. 38E-03 

6.00E+02 1. 16E-06 6. 38E-Ol 1. 16E-08 6. 38E-03 

7.00E+02 1.0IE-06 6. 38E-01 1.0IE-08 6. 38E-03 

8.00E+02 8. 78E-07 6. 38E-Ol O.OOE+OO 6. 39E-03 

9.00E+02 7. 64E-07 6. 39E-Ol O.OOE+OO 6. 39E-03 

1.00E+03 6. 65E-07 6. 39E-Ol O.OOE+OO 6. 39E-03 

2.00E+03 1. 66E-07 6. 39E-Ol O.OOE+OO 6. 39E-03 

3.00E+03 4. 15E-08 . 6. 39E-Ol O.OOE+OO 6. 39E-03 

4.00E+03 1.03E-08 6. 39E-Ol O.OOE+OO 6. 39E-03 

B-15 
CLASS D AHAD = 1 HICK.ON STABLE MAGNESIUM 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.7SE-Ol 2. 26E-Ol 3.03E-04 1.24E-0l 6.2SE-Ol 

2.00E-Ol 3.19E-Ol 2. OlE-Ol 2. 96E-07 9. 44E-02 6.l4E-Ol 

3.00E-Ol 3.39E-0l 1.79E-Ol O.OOE+OO 8.22E-02 6.0lE-Ol 

4.00E-Ol 3.S2E-Ol 1.60E-Ol O.OOE+OO 7. 67E-02 S.S9E-Ol 

S.OOE-Ol 3.6lE-0l 1. 43E-0l O.OOE+OO 7.29E-02 S.77E-Ol 

6.00E-Ol 3.70E-Ol 1.27E-Ol O.OOE+OO 6. 93E-02 S.66E-0l 

7.00E-Ol 3.77E-Ol 1.13E-0l O.OOE+OO 6. S7E-02 S.S6E-Ol 

8.00E-Ol 3.S4E-Ol 1.OlE-Ol O.OOE+OO 6.20E-02 S.46E-Ol 

9.00E-Ol 3.90E-Ol S.96E-02 O.OOE+OO S.S2E-02 S~38E-Ol 

1.OOE+OO 3.9SE-Ol 7. 97E-02 O.OOE+OO S.44E-02 S.30E-Ol 

2.00E+OO 4. 27E-Ol 2. 42E-02 O.OOE+OO 2. 42E-02 4. 76E-Ol 

3.00E+OO 4.3SE-Ol 7.13E-03 O.OOE+OO 9.S7E-03 4.S2E-Ol 

4.00E+OO 4.3SE-Ol 2.0SE-03 O.OOE+OO 3.63E-03 4.41E-Ol 

S.OOE+OO 4. 33E-Ol S.8lE-04 O.OOE+OO 1.3SE-03 4.3SE-Ol 

6.00E+OO 4.3lE-Ol 1. 62E-04 O.OOE+OO 4.99E-04 4.3lE-Ol 

7.00E+OO 4.2SE-Ol 4.47E-OS O.OOE+OO 1. 84E-04 4.2SE-Ol 

8.00E+OO 4.2SE-0l 1.22E-OS O.OOE+OO 6.7SE-OS 4.2SE-Ol 

9.00E+OO 4.22E-Ol 3. 32E-06 O.OOE+OO 2.S0E-OS 4. 22E-Ol 

1.OOE+Ol 4.l9E-0l 8.96E-07 O.OOE+OO 9.l8E-06 4.19E-Ol 

2.00E+Ol 3.91E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.91E-Ol 

3.00E+Ol 3.6SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 3.6SE-Ol 

4.00E+Ol 3.40E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.40E-Ol 

S.OOE+Ol 3.1SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 3.lSE-Ol 

6.00E+Ol 2. 96E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 96E-Ol 

7.00E+Ol 2. 76E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 76E-Ol 

8.00E+Ol 2.S8E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.S8E-Ol 

9.00E+OI 2.4IE-0l O.OOE+OO O.OOE+OO O.OOE+OO 2.4lE-Ol 

1.OOE+02 2.2SE-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.2SE-Ol 

2.00E+02 1.12E-OI O.OOE+OO O.OOE+OO O.OOE+OO- 1.12E-Ol 

3.00E+02 S.6lE-02 O.OOE+OO O.OOE+OO O.OOE+OO S.6lE-02 

4.00E+02 2.81E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.SlE-02 

S.OOE+02 1.40E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-02 

6.00E+02 7.02E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.02E-03 

7.00E+02 3.S1E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.SlE-03 

8.00E+02 I. 76E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 76E-03 

9.00E+02 8.7SE-04 O.OOE+OO O.OOE+OO O.OOE+OO 8. 78E-04 

1.OOE+03 4. 39E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 39E-04 

2.00E+03 4.2SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.2SE-07 

B-16 
CLASS D AKAD .. 1 HICRON srABU HlGRBSIUH. 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 1.IIE-02 5. 47E-OS 

2.00E-OI 2.4IE-02 6.0SE-04 

3.00E-OI 3.60E-02 1. 99E-03 

4.00E-OI 4. 64E-02 4.16E-03 

S.OOE-Ol S.S3E-02 6. 97E-03 

6.00E-OI 6.30E-02 I.02E-02 

7.00E-0l 6. 96E-02 I. 38E-02 

8.00E-OI 7.S3E-02 1.7SE-02 

9.00E-OI 8.02E-02 2.13E-02 

I.OOE+OO 8. 45E-02 8.4SE-02 2.SIE-02 2.S1E-02 

2.00E+OO 2. 38E-02 I.08E-0l 3.02E-02 S.53E-02 

3.00E+OO 9.04E-03 1.l7E-OI 1.46E-02 6. 99E-02 

4.00E+OO 4. 82E-03 I. 22E-OI S.9SE-03 7. S9E-02 

S.OOE+OO 3.S4E-03 I. 26E-OI 2. 28E-03 7.8IE-02 

6.00E+OO 3.ISE-03 I. 29E-OI 8.S1E-04 7.90E-02 

7.00E+OO 3.02E-03 I. 32E-OI 3.1SE-04 7. 93E-02 

8.00E+OO 2. 97E-03 1.3SE-OI 1.16E-04 7.94E-02 

9.00E+OO 2. 94E-03 I. 38E-OI 4. 29E-OS 7.9SE-02 

I.OOE+OI 4.91E-03 1.4IE-OI 1. S8E-OS 7.9SE-02 

2.00E+Ol 2. 72E-03 1. 69E-OI O.OOE+OO 7.9SE-:-02 

3.00E+Ol 2. 54E-03 1.9SE-Ol O.OOE+OO 7.9SE-02 

4.00E+Ol 2. 37E-03 2.19E-OI O"OOE+OO 7.9SE-02 

S.OOE+OI 2.2IE-03 2. 42E-Ol O.OOE+OO 7.9SE-02 

6.00E+Ol ·2.06E-03 2. 63E-OI O.OOE+OO 7.9SE-02 

7.00E+Ol I. 92E-03 2. 83E-Ol O.OOE+OO 7.9SE-02 

8.00E+OI I. 79E-03 3.02E-OI O.OOE+OO 7.9SE-02 

9.00E+OI I. 67E-03 3.19E-Ol O.OOE+OO 7.9SE-02 

1.OOE+02 I.S6E-03 3.3SE-Ol O.OOE+OO 7.9SE-02 

2.00E+02 7.8IE-04 4. 47E-0l O.OOE+OO 7.9SE-02 

3.00E+02 3.90E-04 S.03E-OI O.OOE+OO 7.9SE-02 

4.00E+02 1.9SE-04 S.32E-OI O.OOE+OO 7. 95E-02 

5.00E+02 9. 76E-OS S.46E-ol O.OOE+OO 7.9SE-02 

6.00E+02 4. 88E-OS S.S3E-Ol O.OOE+OO 7.9SE-02 

7.00E+02 2. 44E-OS S.S6E-Ol O.OOE+OO 7.9SE-02 

8.00E+02 1. 22E-OS S.S8E-Ol O.OOE+OO 7.9SE-02 

9.00E+02 6.1IE-06 5. 59E-Ol O.OOE+OO 7.9SE-02 

1.OOE+03 3.0SE-06 S.S9E-Ol O.OOE+OO 7.9SE-02 

B-17 
CLASS D AHAD ... 1 MICRON STABLE ALUMINUM 27 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 2.57E-OI 2. 26E-OI 3.03E-04 I.56E-Ol 6. 39E-OI 

2.00E-Ol 2.BlE-OI 2.0lE-Ol 2. 96E-07 1. 55E-Ol 6.3BE-OI 

3.00E-OI 3.03E-OI I.79E-0l O.OOE+OO I.54E-Ol 6. 36E-OI 

4.00E-Ol 3. 22E-Ol 1.60E-OI O.OOE+OO 1.5IE-OI 6. 32E-Ol 

5.00E-Ol 3. 39E-OI 1.43E-OI O.OOE+OO 1. 46E-OI 6.2BE-Ol 

6.00E-OI 3. 54E-OI 1. 27E-Ol O.OOE+OO 1.4lE-Ol 6. 22E-Ol 

7.00E-OI 3. 67E-Ol 1. 13E-Ol O.OOE+OO 1.35E-Ol 6.15E-Ol 

B.OOE-Ol 3. BOE-Ol 1.OlE-Ol O.OOE+OO I.2BE-Ol 6.0BE-Ol 

9.00E-Ol 3.90E-Ol B.96E-02 O.OOE+OO 1.2lE-OI 6.0lE-Ol 

1.OOE+OO 4.00E-OI 7. 97E-02 O.OOE+OO 1.14E-Ol 5. 93E-Ol 

2.00E+OO 4.52E-OI 2. 42E-02 O.OOE+OO 5.19E-02 5.2BE-OI 

3.00E+OO 4. 66E-OI 7.13E-03 O.OOE+OO 2.07E-02 4. 94E-Ol 

4.00E+OO 4.6BE-Ol 2.05E-03 O.OOE+OO 7.B6E-03 4.7BE-Ol 

5.00E+OO 4. 66E-Ol 5. BIE-04 O.OOE+OO 2. 93E-03 4.70E-OI 

6.00E+OO 4. 63E-Ol 1.62E-04 O.OOE+OO 1.09E-03 4. 65E-Ol 

7.00E+OO 4.60E-Ol 4. 47E-05 O.OOE+OO 4.00E-04 4.6lE-OI 

B.OOE+OO 4. 57E-Ol 1. 22E-05 O.OOE+OO 1.47E-04 4. 57E-Ol 

9.00E+OO 4. 54E-Ol 3. 32E-06 O.OOE+OO 5. 42E-05 4. 54E-Ol 

1.OOE+Ol 4.5lE-Ol 8. 96E-07 O.OOE+OO 2.00E-05 4.5lE-OI 

2.00E+Ol 4.2IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.2IE-Ol 

3.00E+OI 3. 93E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3.93E-Ol 

4.00E+OI 3. 66E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3. 66E-Ol 

5.00E+Ol 3. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-Ol 

6.00E+Ol 3.19E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3.l9E-OI 

7.00E+Ol 2.9BE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.9BE-Ol 

B.OOE+Ol 2.7BE-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.7BE-Ol 

9.00E+OI 2. 59E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 59E-OI 

1.OOE+02 2. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-Ol 

2.00E+02 1.2lE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.2IE-Ol 

3.00E+02 6.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.04E-02 

4.00E+02 3.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-02 

5.00E+02 1.51E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.5lE-02 

6.00E+02 7. 56E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7. 56E-03 

7.00E+02 3.7BE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.7BE-03 

B.OOE+02 1. 89E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. B9E-03 

9.00E+02 9.45E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 45E-04 .... i,', 1.00E+03 4. 73E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4.73E-04 

2.00E+03 4.60E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.60E-07 

B-18 
CLASS D .AHAD - 1 HICROR STABLE ALUHINmI 27 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1. 46E-04 6.07E-OS 

2.00E-Ol 3. 33E-04 7.40E-04 

3.00E-Ol S.36E-04 2.64E-03 

4.00E-Ol 7.S2E-04 S.9lE-03 

S.OOE-Ol 9.SlE-04 1.04E-02 

6.00E-Ol 1. 22E-03 1.60E-02 

7.00E-Ol 1. 47E-03 2. 24E-02 

S.OOE-Ol 1. 73E-03 2. 92E-02 

9.00E-Ol 2.00E-03 3. 64E-02 

1.OOE+OO 2. 27E-03 2. 27E-03 4. 37E-02 4. 37E-02 

2.00E+OO 2. 99E-03 S.26E-03 6.lSE-02 I.06E-Ol 

3.00E+OO 3.l9E-03 S.4SE-03 3.l2E-02 1. 37E-Ol 

4.00E+OO 3. 24E-03 1.17E-02 1.2SE-02 1. SOE-Ol 

S.OOE+OO 3. 24E-03 l.49E-02 4. 93E-03 1. 54E-Ol 

6.00E+OO 3. 22E-03 1.S2E-02 I.SSE-03 1. 56E-Ol 

7.00E+OO 3.20E-03 2.l4E-02 6.SSE-04 1. 57E-Ol 

S.OOE+OO 3.1SE-03 2.4SE-02 2.S3E-04 I.S7E-Ol 

9.00E+OO 3.l6E-03 2.77E-02 9.31E-OS 1. 57E-Ol 

1.00E+Ol 3.l4E-03 3.0SE-02 3. 43E-OS I.S7E-Ol 

2.00E+Ol 2. 93E-03 6.lOE-02 O.OOE+OO 1. 57E-Ol 

3.00E+Ol 2. 73E-03 S.92E-02 O.OOE+OO 1.57E-Ol 

4.00E+Ol 2. 55E-03 1. 15E-Ol O.OOE+OO 1.57E-Ol 

5.00E+Ol 2.3SE-03 1.40E-Ol O.OOE+OO 1. S7E-0l 

6.00E+Ol 2. 22E-03 Ii. 63E-Ol O.OOE+OO 1. 57E-Ol 

7.00E+Ol 2.07E-03 I.S4E-Ol O.OOE+OO 1. 57E-Ol 

S.OOE+Ol 1. 93E-03 2.04E-Ol O.OOE+OO 1. 57E-Ol 

9.00E+Ol 1.SOE-03 2. 23E-Ol O.OOE+OO 1.57E-Ol 

1.OOE+02 1.6SE-03 2.40E-Ol O.OOE+OO i.57E-Ol 

2.00E+02 S,,40E-04 3.6lE-Ol O.OOE+OO 1. 57E-Ol 

3.00E+02 4.20E-04 4.21E-Ol O.OOE+OO 1. 57E-Ol 

4.00E+02 2.10E-04 4. 52E-Ol O.OOE+OO 1.57E-0l 

5.00E+02 1.OSE-04 4. 67E-Ol O.OOE+OO 1.57E-ol 

6.00E+02 5. 26E-05 4. 74E-Ol O.OOE+OO 1. 57E-0l 

", ' 7.00E+02 2. 63E-05 4.7SE-Ol O.OOE+OO 1. 57E-Ol " S.OOE+02 1.3lE-OS 4. SOE-Ol O.OOE+OO 1.57E-0l 

9.00E+02 6. 57E-06 4.SlE-Ol O.OOE+OO 1.S7E-Ol 

1.OOE+03 3. 29E-06 4.SlE-Ol O.OOE+OO 1. 57E-Ol 

B-19 
CLASS D AMAD = 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 56E-Ol 2. 26E-Ol 3.03E-04 1. 56E-Ol 6. 38E-Ol 

2.00E-Ol 2. 79E-Ol 2.0lE-Ol 2. 96E-07 1. 55E-Ol 6.36E-Ol 

3.00E-Ol 2. 99E-Ol 1.79E-Ol O.OOE+OO 1.54E-Ol 6.32E-Ol 

4.00E-Ol 3.l6E-Ol 1.60E-Ol O.OOE+OO 1.5lE-Ol 6.27E-Ol 

5.00E-Ol 3.'32E-Ol 1.43E-Ol O.OOE.+OO 1. 46E-Ol 6.20E-Ol 

6.00E-Ol 3.45E-Ol 1. 27E-Ol O.OOE+OO 1.4lE-Ol 6.l3E-Ol 

7.00E-Ol 3. 57E-Ol 1.13E-Ol O.OOE+OO 1.35E-Ol 6.05E-Ol 

8.00E-Ol 3.67E-Ol 1.OlE-Ol O.OOE+OO 1.28E-Ol 5. 96E-Ol 

9.00E-Ol 3. 76E-Ol 8. 96E-02 O.OOE+OO 1.2lE-Ol 5. 86E-Ol 

1.OOE+OO 3. 84E-Ol 7. 97E-02 O.OOE+OO 1.14E-Ol 5.77E-Ol 

2.00E+OO 4.l7E-Ol 2. 42E-02 O.OOE+OO 5.l9E-02 4. 93E-Ol 

3.00E+OO 4.l3E-Ol 7.l3E-03 O.OOE+OO 2.07E-02 4.40E-Ol 

4.00E+OO 3. 98E-Ol 2.05E-03 O.OOE+OO 7. 86E-03 4.08E-Ol 

5.00E+OO 3. 83E-Ol 5.8lE-04 O.OOE+OO 2. 93E-03 3. 86E-Ol 

6.00E+OO 3. 68E-Ol 1.62E-04 O.OOE+OO 1.09E-03 3. 69E-Ol 

7.00E+OO 3. 54E-Ol 4. 47E-05 O.OOE+OO 4.00E-04 3. 55E-Ol 

8.00E+OO 3.42E-Ol 1.22E-05 O.OOE+OO 1.47E-04 3. 42E-Ol 

9.00E+OO 3.32E-Ol 3. 32E-06 O.OOE+OO 5. 42E-05 3. 32E-Ol 

1.OOE+Ol 3. 22E-Ol 8. 96E-07 O.OOE+OO 2.00E-05 3.22E-Ol 

2.00E+Ol 2. 65E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 65E-Ol 

3.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.39E-Ol 

4.00E+Ol 2.2lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.2lE-Ol 

5.00E+Ol 2.05E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-Ol 

6.00E+Ol 1.9lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.9lE-Ol 

7.00E+Ol 1.79E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 79E-Ol 

8.00E+Ol 1. 67E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 67E-Ol 

9.00E+Ol 1.55E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.55E-Ol 

1.OOE+02 1.45E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.45E-Ol 

2.00E+02 7. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.25E-02 

3.00E+02 3. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 63E-02 

4.00E+02 1.8lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.8lE,:",02 

5.00E+02 9.07E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-03 

6.00E+02 4. 53E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 53E-03 

7.00E+02 2. 27E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 27E-03 

8.00E+02 1.13E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.13E-03 

9.00E+02 5. 67E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5. 67E-04 

1.OOE+03 2. 84E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 84E-04 ...... ' 2.00E+03 2. 75E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 75E-07 

B-20 
CLASS D AIIAD - 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------- ----------------------- 24-HOlTR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.2SE-03 6.07E-OS 

I 2.00E-01 2. 84E-03 7.40E-04 

3.00E-01 4.S4E-03 2. 64E-03 

4.00E-01 6. 34E-03 S.91E-03 

S.OOE-01 8. 23E-03 1.04E-02 

6.00E-01 1.02E-02 1.60E-02 

7.00E-01 1. 22E-02 2.24E-02 

8.00E-01 1.43E-02 2. 92E,...02 

9.00E-01 1.64E-02 3. 64E-02 

1.00E+OO 1.8SE-02 1.8SE-02 4. 37E-02 4. 37E-02 

2.00E+OO 2. 22E-02 4.07E-02 6. 18E-02 1.06E-OI 

3.00E+OO 2.13E-02 6. 21E-02 3. 12E-02 I. 37E-01 

4.00E+OO 1. 93E-02 8. 14E-02 1. 28E-02 1.S0E-01 

S.OOE+OO 1. 72E-02 9. 86E-02 4. 93E-03 1. S4E-01 

6.00E+00 1.S3E-02 1. 14E-01 1.8SE-03 1.S6E-01 

7.00E+00 1. 36E-02 1. 27E-01 6.8SE-04 1.S7E-01 

8.00E+OO 1.20E-02 1.40E-01 2.S3E-04 1. S7E-0l 

9.00E+00 1.07E-02 1.S0E-01 9. 31E-OS 1. S7E-0l 

1.00E+01 9.SSE-03 1.60E-oi 3. 43E-oS 1.S7E-01 

2.00E+01 3. 67E-03 2. 16E-01 O.OOE+OO 1.S7E-01 

3.00E+01 2.llE-03 2. 43E-01 O.OOE+OO 1. S7E-01 

4.00E+01 1.6SE-03 2. 61E-01 O .. OOE+OO 1. S7E-01 

S.OOE+01 1.46E-03 2.76E-0l O.OOE+OO 1.S7E-Ol 

6.00E+01 1. 34E-03 2.90E-01 O.OOE+OO I.S7E-01 

7.00E+01 1. 24E-03 3.03E-01 O.OOE+OO 1. S7E-01 

8.00E+Ol l.16E-03 3.1SE-01 O.OOE+OO 1. 57E-01 

9.00E+01 1.08E-03 3. 26E-01 O.OOE+OO 1.S7E-01 

1.00E+02 1.01E-03 3. 37E-01 O.OOE+OO 1. 57E-01 

2.00E+02 S.04E-04 4.09E-Ol O.OOE+OO 1. 57E-01 

3.00E+02 2.S2E-04 4.4SE-01 O.OOE+OO 1. 57E-01 

4.00E+02 1. 26E-04 4. 64E-01 O.OOE+OO 1.57E-01 

5.00E+02 6. 31E-OS 4. 73E-01 O.OOE+OO 1. 57E-01 

6.00E+02 3.I5E-OS 4.77E-Ol O.OOE+OO 1.S7E-01 

7.00E+02 1.S8E-OS 4. 79E-01 O.OOE+OO 1. 57E-01 

8.00E+02 7. 89E-06 4.81E-01 O.OOE+OO 1.57E-0l ... 

9.00E+02 3. 94E-06 4.81E-01 O.OOE+OO 1. 57E-01 

1.00E+03 1.97E-06 4.8IE-01 O.OOE+OO I. 57E-Ol 

B-21 
CLASS D MIAD ..: 1 MICROH STABLE PHOSPHORUS 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 32E-Ol 2.26E-Ol 3.03E-04 7.4lE-02 6. 33E-Ol 

2.00E-Ol 3. 85E-Ol 2.0lE-Ol 2. 96E-07 3. 72E-02 6. 23E-Ol 

3.00E-0l 4.02E-Ol 1. 79E-Ol O.OOE+OO 3. 14E-02 6. 13E-Ol 

4.00E-Ol 4. 14E-Ol 1.60E-Ol O.OOE+OO 2. 98E-02 6.03E-Ol 

5.00E-Ol 4.23E-Ol 1. 43E-Ol O.OOE+OO 2.85E-02 5. 94E-Ol 

6.00E-Ol 4.30E-Ol 1. 27E-Ol O.OOE+OO 2.71E-02 5. 84E-Ol 

7.00E-Ol 4. 36E-Ol 1. 13E-Ol O.OOE+OO 2. 56E-02 5.75E-0l 

8.00E-Ol 4. 41E-Ol 1.0lE-0l O.OOE+OO 2.41E-02 5. 66E-Ol 

9.00E-Ol 4. 46E-Ol 8. 96E-02 O.OOE+OO 2.25E-02 5.58E-Ol 

1.00E+OO 4.49E-Ol 7. 97E-02 O.OOE+OO 2.lOE-02 5.50E-Ol 

2.00E+OO 4. 53E-Ol 2. 42E-02 O.OOE+OO 9. 24E-03 4. 87E-Ol 

3.00E+OO 4. 38E-Ol 7.l3E-03 O.OOE+OO 3. 64E-03 4.49E-Ol 

4.00E+OO 4.2lE-Ol 2.05E-03 O.OOE+OO 1.38E-03 4. 25E-Ol 

5.00E+OO 4.06E-Ol 5.8lE-04 O.OO!,!+OO 5.l2E-04 4. 07E....,() 1 

6.00E+OO 3. 93E-Ol 1.62E-04 O.OOE+OO 1. 89E-04 3.94E-Ol 

7.00E+OO 3. 82E-Ol 4. 47E-05 O.OOE+OO 6. 98E-05 3. 82E-Ol 

8.00E+OO 3.72E-Ol 1.22E-05 O.OOE+OO 2.57E-05 3.72E-Ol 

9.00E+OO 3. 64E-Ol 3. 32E-06 O.OOE+OO 9. 47E-06 3. 64E-Ol 

1.00E+Ol 3. 56E-01 8. 96E-07 O.OOE+OO 3. 48E-06 3.56E-Ol 

2.00E+Ol 2. 99E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 99E-Ol 

3.00E+Ol 2. 62E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 62E-Ol 

4.00E+01 2. 36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 36E-Ol 

5.00E+Ol 2.I8E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 18E-Ol 

6.00E+Ol 2.05E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-Ol 

7.00E+Ol 1.96E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.96E-0l 

8.00E+OI 1. 89E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 89E-Ol 

9.00E+Ol 1. 84E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 84E-Ol 

1.00E+02 1.80E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.80E-Ol 

2.00E+02 1.66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 66E-Ol 

3.00E+02 1. 59E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 59E-Ol 

4.00E+02 1.51E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.51E-Ol 

5.00E+02 1.45E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.45E-Ol 

6.00E+02 1.38E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 38E-Ol 

7.00E+02 1. 32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-Ol 

8.00E+02 1.26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.26E-OI 

9.00E+02 1.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-Ol .".j 

, , 1.00E+03 1.I5E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 15E-Ol 

2.00E+03 7.23E-02 O.OOE+OO O.OOE+OO O.OOE+OO· 7. 23E-02 

4.00E+03 2. 87E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 87E-02 

8.00E+03 4. 52E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 52E-03 

1.00E+04 1. 79E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.79E-03 

2.00E+04 4.I2E-06 O.OOE+OO O.OOE+OO O.OOE+OO 4. 12E-06 

B-22 
CLASS D AHAD - 1 HICRON STABLE PHOSPHORUS 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 5.80E-03 6. 86E-04 

2.00E-Ol 1.40E-02 1. 93E-03 

3.00E-Ol 2. 23E-02 3.57E-03 

4.00E-Ol 3.02E-02 5. 48E-03 

5.00E-Ol 3. 79E-02 7. 57E-03 

6.00E-Ol 4.5lE-02 9.17E-03 

7.00E-Ol 5.2lE-02 1.20E-02 

8.00E-Ol 5. 87E-02 1.43E-02 

9.00E-Ol 6.50E-02 1.65E-02 

1.OOE+OO 7.09E-02 7.09E-02 1.87E-02 1.87E-02 

2.00E+OO 4. 59E-02 1.17E-Ol 1.69E-02 3.55E-02 

3.00E+OO 2.89E-02 1.46E-Ol 8.8lE-03 4. 44E-02 

4.00E+OO 1. 99E-02 1. 66E-Ol 4.47E-03 4. 88E-02 

5.00E+OO 1. 49E-02 1. 81E-0l 2. 52E-03 5.l4E-02 

6.00E+OO 1.20E-02 1.93E-Ol 1.66E-03 5.30E-02 

7.00E+OO 1.OlE-02 2.03E-Ol 1. 24E-03 5. 43E-02 

8.00E+OO 8.77E-03 2.llE-Ol 1.02E-03 5. 53E-02 

9.00E+OO 7. 79E-03 2.l9E-Ol 8. 82E-04 S.62E-02 

1.OOE+Ol 7.0SE-03 2.26E-Ol 7.90E-04 5. 69E-02 

2.00E+Ol 4.09E-03 2.17E-Ol 4.S4E-04 6. 26E-02 

3.00E+Ol 2. 83E-03 3.l1E-Ol 3.l5E-04 6. 63E-02 

4.00E+Ol 1. 99E-03 3. 34E-Ol 2.2lE-04 6.89E-02 

S.OOE+Ol 1.40E-03 3.5lE-0l 1. 56E-04 7.07E-02 

6.00E+Ol 9. 97E-04 3.62E-Ol 1.l1E-04 7.20E-02 

7.00E+Ol 7.lSE-04 3.7lE-0l 7.94E-OS 7.30E-02 

8.00E+Ol '5.l8E-04 3. 17E-Ol 5. 76E-05 7.36E-02 

9.00E+Ol 3. 82E-04 3.8lE-0l 4. 24E-05 7. 41E-02 

1.OOE+02 2. 87E-04 3. 84E-Ol 3.l9E-05 7.45E-02 

2.00E+02 7. 46E-OS 3. 97E~0l 8.30E-06 7. 59E-02 

3.00E+02 6.60E-05 4.04E-Ol 7. 35E-06 7. 67E-02 

4.00E+02 6. 28E-OS 4.l0E-0l 7.00E-06 7. 74E-02 

5.00E+02 5. 99E-05 4.l6E-Ol 6. 68E-06 7.8lE-02 

6.00E+02 5. 72E-05 4.22E-Ol 6. 38E-06 7. 87E-02 

7.00E+02 5.4SE-05 4. 28E-Ol 6.09E-06 7. 93E-02 

8.00E+02 S.20E-OS 4. 33E-Ol 5. 82E-06 7.99E-02 

9.00E+02 4. 96E-OS 4.38E-Ol 5.S6E-06 8.05E-02 ,,- ~" 1.OOE+03 4. 73E-05 4. 43E-Ol 5.3lE-06 8.10E-02 

2.00E+03 2. 92E-05 4.8lE-Ol 3. 34E-06 8. 53E-02 

3.00E+03 1.76E-OS 5.06E-0l 2.llE-06 8.80E-02 

4.00E+03 1. OlE-OS 5. 21E-0l 1. 33E-06 8.97E-02 

5.00E+03 S.24E-06 5.30E-Ol 8.36E-07 9.07E-02 

6.00E+03 2.00E-06 S.36E-Ol 5.27E-07 9.l4E-02 

B-23 
CLASS D .AHAD co 1 HICR.OH BALFLIFE= 1.438+01 DAYS PHOSPHORUS 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.3lE-Ol 2.2SE-Ol 3.0lE-04 7. 38E-02 6.30E-Ol 

2.00E-Ol 3.8lE-Ol 1.99E-Ol 2. 93E-07 3.6SE-02 6.l7E-Ol 

3.00E-Ol 3.97E-Ol 1.77E-OI O.OOE+OO 3.09E-02 6.04E-OI 

4.00E-OI 4.06E-OI 1. S7E-OI O.OOE+OO 2. 92E-02 S.92E-Ol 

5.00E-OI 4.13E-OI 1.39E-OI O.OOE+OO 2.7SE-02 S.79E-OI 

6.00E-OI 4.ISE-OI 1.23E-Ol O.OOE+OO 2. 63E-02 S.67E-Ol 

7.00E-0l 4.22E-OI 1.09E-OI O.OOE+OO 2. 47E-02 5.S6E-OI 

S.OOE-Ol 4.2SE-Ol 9.6SE-02 O.OOE+OO 2.3lE-02 S.4SE-Ol 

9.00E-Ol 4. 27E-Ol S.5SE-02 O.OOE+OO 2.l6E-02 S.34E-OI 

I.OOE+OO 4.2SE-Ol 7.S9E-02 O.OOE+OO 2.00E-02 S.23E-Ol 

2.00E+OO 4.11E-Ol 2.20E-02 O.OOE+OO S.39E-03 4. 42E-Ol 

3.00E+OO 3. 79E-OI 6.17E-03 O.OOE+OO 3.ISE-03 3.SSE-OI 

4.00E+OO 3. 47E-Ol 1.69E-03 O.OOE+OO 1.13E-03 3.50E-OI 

S.OOE+OO 3.19E-Ol 4.S6E-04 O.OOE+OO 4.02E-04 3.19E-Ol 

6.00E+OO 2. 94E-Ol 1.21E-04 O.OOE+OO 1. 42E-04 2. 94E-OI 

7.00E+OO 2. 72E-Ol 3.ISE-OS O.OOE+OO 4. 97E-OS 2. 72E-Ol 

S.OOE+OO 2.S3E-Ol S.30E-06 O.OOE+OO 1. 74E-OS 2.S3E-Ol 

9.00E+OO 2. 3 SE-O 1 2.15E-06 O.OOE+OO 6.l2E-06 2.3SE-Ol 

1.OOE+Ol 2.19E-OI S.S2E-07 O.OOE+OO 2.14E-06 2.l9E-Q1 

2.00E+Ol 1.14E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.14E-Ol 

3.00E+Ol 6.l2E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.l2E-02 

4.00E+Ol 3. 39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 

S.OOE+Ol 1.93E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 

6.00E+Ol 1.12E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-02 

7.00E+Ol 6.S6E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.S6E-03 

S.OOE+Ol 3.90E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.90E-03 

9.00E+Ol 2. 34E-03 O.OOE+OO O.COE+OO O.OOE+OO 2.34E-03· 

1.OOE+02 1.4IE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.41E-03 

2.00E+02 1.02E-05 O.OOE+OO O.OOE+OO O.QOE+OO I.02E-OS 

3.00E+02 7.60E-OS O.OOE+OO O.OOE+OO O.OOE+OO 7.60E-OS 

B-24 
CLASS D AII&D - 1 KICRON BALFLIP'E- 1.43E+Ol DAYS PHOSPHOJtUS 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol s.17E-03 6.83E-04 

2.00E-Ol 1. 39E-02 1. 92E-03 

3.00E-Ol 2. 19E-02 3.s2E-03 

4.00E-01 2. 96E-02 s.38E-03 

s.OOE-Ol 3. 69E-02 7. 39E-03 

6.00E-01 4. 38E-02 9.49E-03 

7.00E-01 s.03E-02 1. 16E-02 

8.00E-01 s.64E-02 1. 37E-02 

9.00E-01 6. 22E-02 1.s8E-02 

1.00E+OO 6. 76E-02 6. 76E-02 1. 78E-02 1. 78E-02 

2.00E+OO 4. 17E-02 1.06E-01 1.s3E-02 3. 23E-02 

3.00E+OO 2.s0E-02 1. 26E-01 7. 62E-03 3. 83E-02 

4.00E+OO 1.64E-02 1.36E-01 3. 68E-03 4.02E-02 

s.OOE+OO 1. 17E-02 1. 42E-01 1. 98E-03 4.03E-02 

6.00E+OO 8. 98E-03 1.44E-0l 1.24E-03 3. 96E-02 

7.00E+OO 7. 19E-03 1.44E-01 8. 84E-04 3. 86E-02 

8.00E+OO s.9sE-03 1.43E-0l 6. 91E-04 3.7sE-02 

9.00E+OO s.04E-03 1. 42E-01 s.70E-04 3. 63E-02 

1.00E+01 4. 34E-03 1.39E-01 4. 86E-04 3.s1E-02 

2.00E+01 1.ssE-03 1.0sE-Ol 1. 72E-04 2.37E-02 

3.00E+01 6. 61E-04 7.2sE-02 7.3sE-05 1.ssE-02 

4.00E+01 <2. 86E-04 4.80E-02 3. 18E-05 9.90E-03 

s.OOE+01 1. 24E-04 3.lOE-02 1. 38E-05 6.26E-03 

6.00E+01 s.43E-Os 1. 97E-02 6.03E-06 3. 92E-03 

7.00E+Ol 2.40E-Os 1. 24E-02 2.66E-06 2.4sE-03 

8.00E+01 1.07E-Os 7.17E-03 1.19E-06 1.s2E-03 

9.00E+Ol 4.8sE-06 4. 84E-03 s.39E-07 9. 42E-04 

1.00E+02 2.2sE-06 3.01E-03 2.s0E-07 5. 83E-04 

,. '., ' ... 

B-25 
CLASS D AHA» - 1 MICROR STABLE SULPIIUB. 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------~------- SYSTEMIC NASAL GI TOTAL· 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.90E-Ol 2.26E-Ol 3.03E-04 7.4lE-02 S.90E-Ol 

2.00K-Ol 2.90E-Ol 2.0lE-Ol 2. 96E-07 3. 72E-02 S.29E-Ol 

3.00E-Ol 2.63E-0l 1.79E-0l O.OOE+OO 3.l4E-02 4. 74E-Ol 

4.00E-Ol 2.3BE-Ol 1.60E-Ol O.OOE+OO 2.9BE-02 4. 27E-Ol 

S.OOE-Ol 2.l7E-Ol 1.43E-0l O.OOE+OO 2. BSE-02 3.BBE-Ol 

6.00E-Ol 2.0lE-Ol 1.27E-Ol O.OOE+OO 2.71E-02 3.SSE-Ol 

7.00E-Ol 1.B7E-Ol 1.13E-0l O.OOE+OO 2.S6E-02 3. 26E-Ol 

B.OOE-Ol I. 76E-Ol I.OIE-Ol O.OOE+OO 2.4lE-02 3.0lE-Ol 

9.00E-Ol I. 67E-0l B.96E-02 O.OOE+OO 2.2SE-02 2. BOE-Ol 

1.OOE+OO 1.60E-Ol 7. 97E-02 O.OOE+OO 2.lOE-02 2.6lE-Ol 

2.00E+OO 1.27E-0l 2. 42E-02 O.OOE+OO 9. 24E-03 1.60E-Ol 

3.00E+OO 1.l7E-Ol 7.DE-03 O.OOE+OO 3. 64E-03 I. 27E-Ol 

4.00E+OO 1.12E-0l 2.0SE-03 O.OOE+OO I. 38E-03 1.l5E-OI 

S.OOE+OO 1.OBE-OI S.BlE-04 O.OOE+OO S.12E-04 1.09E-OI 

6.00E+OO 1.OSE-0l 1. 62E-04 O.OOE+OO I.B9E-04 I.06E-Ol 

7.00E+OO 1.03E-OI 4. 47E-OS O.OOE+OO 6.9BE-OS 1.03E-Ol 

8.00E+OO 1.OOE-Ol 1.22E-OS O.OOE+OO 2.S7E-OS 1.OOE-Ol 

9.00E+OO 9. 79E-02 3. 32E-06 O.OOE+OO 9. 47E-06 9. 79E-02 

1.OOE+Ol 9.S6E-02 8.96E-07 O.OOE+OO 3. 48E-06 9.S6E-02 

2.00E+Ol 7. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 63E-02 

3.00E+Ol 6. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 27E-02 

4.00E+Ol S.30E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.30E-02 

S.OOE+OI 4. 62E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 62E-02 

6.00E+Ol 4.l3E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l3E-02 

7.00E+OI 3.7BE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.7BE-02 

8.00E+OI 3.S3E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 53E-02 

9.00E+OI 3.3SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 35E-02 

1.OOE+02 3. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 22E-02 

2.00E+02 2.B4E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.B4E-02 

3.00E+02 2. 74E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 74E-02 

4.00E+02 2. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 64E-02 

5.00E+02 2. 55E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S5E-02 

6.00E+02 2. 47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 47E-02 

7.00E+02 2. 38E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.3BE-02 

8.00E+02 2.30E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.30E-02 

9.00E+02 2. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 22E-02 

1.OOE+03 2.15E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.lSE-02 

2.00E+03 1. 52E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.S2E-02 

4.00E+03 7. S9E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.59E-03 

8.00E+03 1.90E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.90E-03 

1.OOE+04 9. SOE-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.50E-04 

2.00E+04 2. 97E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2. 97E-OS 

B-26 
CLASS D .AHAD - 1 MICRON STABLE SULPHUR. 32 

TIME AFTER. FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR. ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-0l 4. 39E-02 4.92E-03 

2.00E-Ol 9.9lE-02 1.14E-02 

3.00E-Ol 1. 48E-Ol 1. 75E-02 

4.00E-Ol 1. 89E-Ol 2.3lE-02 

5.00E-O] 2. 23E-Ol 2.8lE-02 

6.00E-Ol 2. 52E-Ol 3. 27E-02 

7.00E-Ol 2.76E-0l 3. 69E-02 

8.00E-Ol 2. 97E-Ol 4.08E-02 

9.00E-Ol 3.l5E-Ol 4. 43E-02 

1.OOE+OO 3.3lE-OI 3.3lE-OI 4. 75E-02 4. 75E-02 

2.00E+OO 7. 99E-02 4.11E-0l 2.07E-02 6. 82E-02 

3.00E+OO 2. 45E-02 4.35E-Ol 8. 33E-03 7. 65E-02 

4.00E+OO 9.06E-03 4. 44E-Ol 3. 27E-03 7. 98E-02 

5.00E+OO 4. 38E-03 4. 49E-Ol 1. 35E-03 8.11E-02 

6.00E+OO 2. 94E-03 4. 52E-Ol 6.50E-04 8.l8E-02 

7.00E+OO 2. 46E-03 4. 54E-Ol 3. 93E-04 8. 22E-02 

8.00E+OO 2. 27E-03 4.56E-Ol 2. 97E-04 8. 25E-02 

9.00E+OO 2.l7E-03 4. 59E-Ol 2. 57E-04 8. 27E-02 

1.OOE+OI 2.08E-03 4.6lE-0l 2. 38E-04 8.30E-02 

2.00E+Ol I. 47E-03 4. 78E-OI I. 64E-04 8. 49E-02 

3.00E+Ol I.05E-03 4.90E-OI 1.16E-04 8. 63E-02 

4.00E+OI 7. 42E-04 4.99E-OI 8. 24E-05 8. 72E-02 

5.00E+OI 5. 27E-04 5.05E-Ol 5. 86E-05 8. 79E-02 

6.00E+Ol 3. 76E-04 5.09E-Ol ".17E-05 8. 84E-02 

7.00E+Ol 2. 68E-04 5.l3E-Ol 2.98E-05 8. 87E-02 

8.00E+Ol 1. 92E-04 5.15E-OI 2.l4E-05 8.90E-02 

9.00E+Ol 1. 39E-04 5.16E-OI I. 54E-05 8. 92E-02 

1.OOE+02 1.OIE-04 S.18E-Ol 1.!2E-05 8. 93E-02 

2.00E+02 I. 11E-05 5.2lE-0l 1.30E-06 8.97E-02 

3.00E+02 8. 63E-06 5. 22E-OI 9. 59E-07 8. 98E-02 

4.00E+02 _8. 25E-06 5.23E-Ol 9.17E-07 8.99E-02 

5.00E+02 7. 97E-06 5. 24E-Ol 8. 85E-07 9.00E-02 

6.00E+02 7.70E-06 5. 24E-Ol 8.55E-07 9.01E-02 

7.00E+02 7.43E-06 5.25E-Ol 8. 26E-07 9.01E-02 

8.00E+02 7.18E-06 5. 26E-Ol 7.98E-07 9.02E-02 

9.00E+02 6. 94E-06 5. 27E-Ol 7.11E-07 9.03E-02 

1.OOE+03 6.70E-06 5. 27E-Ol 7.44E-07 9.04E-02 .:' 'I" 2.00E+03 4. 74E-06 5. 33E-OI 5. 26E-07 9.lOE-02 

4.00E+03 2.37E~06 5 .. 40E-Ol 2. 63E-07 9.l8E-02 

8.00E+03 6.0lE-07 5.45E-OI 6. 58E-08 9. 23E-02 

I.OOE+04 3.07E-07 5. 46E-OI 3. 29E-08 9. 24E-02 

2.00E+04 3.00E-08 5.47E-Ol O.OOE+OO 9. 25E-02 

B-27 
CLASS D AHAD ... 1 MICRON BALFLIFE= 8.74B+01 DAYS SULPHUR. 3S 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 2.90E-OI 2. 26E-Ol 3.02E-04 7.4IE-02 S.90E-OI 

2.00E-OI 2.90E-Ol 2.01E-Ol 2.9SE-07 3.71E-02 S.28E-Ol 

3.00E-0l 2. 62E-OI 1.79E-OI O.OOE+OO 3. 13E-02 4. 73E-Ol 

4.00E-OI 2.37E-OI I.S9E-OI O.OOE+OO 2. 97E-02 4.26E-OI 

S.OOE-OI 2.16E-OI 1. 42E-OI O.OOE+OO 2. 84E-02 3.87E-0l 

6.00E-OI 2.00E-OI 1. 26E-Ol O.OOE+OO 2. 69E-02 3.S3E-Ol 

7.00E-OI I. 86E-Ol 1.12E-OI O.OOE+OO 2.S4E-02 3. 24E-Ol 

8.00E-OI 1.7SE-OI I.OOE-Ol O.OOE+OO 2. 39E-02 2. 99E-OI 

9.00E-OI 1.66E-Ol 8. 89E-02 O.OOE+OO 2. 24E-02 2.78E-0l 

I.OOE+OO 1.S9E-Ol 7.9IE-02 O.OOE+OO 2.09E-02 2.S9E-Ol 

2.00E+OO 1.2SE-Ol 2. 38E-02 O.OOE+OO 9.10E-03 I.S8E-OI 

3.00E+OO 1.14E-OI 6. 96E-03 O.OOE+OO 3.SSE-03 1. 24E-OI 

4.00E+OO I.08E-OI 1.99E-03 O.OOE+OO 1.33E-03 l.llE-OI 

S.OOE+OO I.04E-OI S. S8E-04 O.OOE+OO 4. 93E-04 I.OSE-OI 

6.00E+OO I.OOE-OI 1. S4E-04 O.OOE+OO 1.8IE-04 I.OIE-OI 

7.00E+OO 9. 72E-02 4. 23E-OS O.OOE+OO 6.61E-OS 9. 73E-02 

8.00E+OO 9.4IE-02 1.ISE-OS O.OOE+OO 2.4IE-OS 9.4IE-02 

9.00E+OO 9.11E-02 3.09E-06 O.OOE+OO 8.8IE-06 9.11E-02 

I.OOE+OI 8. 83E-02 8. 28E-07 O.OOE+OO 3. 22E-06 8. 83E-02 

2.00E+OI 6.SIE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.SIE-02 

3.00E+OI 4. 94E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.94E-02 

4.00E+OI 3. 86E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 86E-02 

S.OOE+OI 3.11E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.11E-02 

6.00E+OI 2.S7E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. S7E-02 

7.00E+OI 2.17E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.17E-02 

8.00E+Ol 1.87E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 87E-02 

9.00E+OI 1. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.64E-02 

I.OOE+02 1.46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 46E-02 

2.00E+02 S.82E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.82E-03 

3.00E+02 2.S4E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.S4E-03 

4.00E+02 ~.IIE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.IIE-03 

S.OOE+02 4.8SE-04 O.OOE+OO O.OOE+OO O.OOE+OO 4.8SE-04 

6.00E+02 2.12E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2.12E-04 

7.00E+02 9.27E-OS O.OOE+OO O.OOE+OO O.OOE+OO 9. 27E-OS 

8.00E+02 4.0SE-OS O.OOE+OO O.OOE+OO O.OOE+OO 4.0SE-OS 

9.00E+02 1.77E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.77E-OS 1-·. I.OOE+03 7.7SE-06 O.OOE+OO O.OOE+OO O.OOE+OO 7.75E-06 

B-28 
ClASS D AHAD - 1 MICllOR BALFLII'E- 8.74E+Ol DAYS SULPBUI. 3S 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 4. 39E-02 4.92E-03 

2.00E-Ol 9. 89E-02 1. 14E-02 

3.00E-Ol 1. 47E-01 1.75E-02 

4.00E-Ol 1. 88E-ol 2.30E-02 

5.00E-Ol 2. 22E-Ol 2.80E-02 

6.00E-Ol 2. 51E-Ol 3. 26E-02 

7.00E-Ol 2.75E-Ol 3. 67E-02 

8.00E-01 2. 95E-Ol 4.05E-02 

9.00E-Ol 3. 13E-01 4.40E-02 

1.00E+00 3. 28E-Ol 3. 28E-Ol 4. 72E-02 4. 72E-02 

2.00E+00 7. 87E-02 4.04E-Ol 2.03E-02 6. 71E-02 

3.00E+00 2.40E-02 4. 25E-Ol 8. 13E-03 7.47E-02 

4.00E+00 8. 78E-03 4.30E-Ol 3. 17E-03 7. 73E-02 

5.00E+00 4. 21E-03 4. 31E-Ol 1.30E-03 7.80E-02 

6.00E+00 2.80E-03 4. 31E-01 6. 19E-04 7.80E-02 

7.00E+00 2. 33E-03 4.30E-Ol 3. 72E-04 7.77E-02 

8.00E+00 2. 13E-03 4. 28E-ol 2.79E-04 7.74E-02 

9.00E+00 2.02E-03 4. 27E-01 2. 39E-04 7.70E-02 

1.00E+Ol 1. 93E-03 4.25E-Ol 2.20E-04 7. 66E-02 

2.00E+Ol 1. 26E-03 4.08E-Ol 1.40E-04 7. 24E-02 

3.00E+Ol 8.24E-04 3. 86E-01 9. 16E-05 6.80E-02 

4.00E+Ol 5.40E-04 3. 63E-Ol 6.00E-05 6. 35E-02 

5.00E+Ol 3.55E-04 3.40E-ol 3. 94E-05 5. 91E-02 

6.00E+Ol 2. 33E-04 3. 17E-Ol 2. 59E-05 5. 49E-02 

7.00E+Ol 1.54E-04 2.94E-Ol 1.71E-05 5.10E-02 

8.00E+Ol 1.02E-04 2. 73E-ol 1. 13E-05 4. 72E-02 

9.00E+Ol 6.80E-05 2.53E-Ol 7.55E-06 4. 37E-02 

1.00E+02 4. 56E-05 2. 34E-Ol 5.07E-06 4.04E-02 

2.00E+02 2.40E-06 1.07E-01 2.66E-07 1. 84E-02 

3.00E+02 8.00E-07 4. 84E-02 8. 89E-08 8. 33E-03 

4.00E+02 3. 46E-07 2. 19E-02 3. 85E-08 3. 77E-03 

5.00E+02 1. 51E-07 9. 95E-03 1. 68E-08 1.71E-03 

6.00E+02 6. 62E-08 4.51E-03 O.OOE+OO 7. 74E-04 

7.00E+02 2. 89E-08 2.04E-03 O.OOE+OO 3. 51E-04 

8.00E+02 1. 26E-08 9. 26E-04 O.OOE+OO 1.59E-04 

.,1 "y" 

B-29 
CLASS D AHAD - 1 MICR.oN STABLE CHLORINE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 89E-Ol 2.26E-Ol 3."03E-04 2.l7E-02 6.37E-Ol 

2.00E-Ol 4.3lE-Ol 2.0lE-Ol 2.96E-07 2. 28E-03 6.34E-Ol 

3.00E-Ol 4. SlE-Ol 1.79E-Ol O.OOE+OO 4.lSE-04 6.3lE-Ol 

4.00E-Ol 4. 68E-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 6.28E-Ol 

S.OOE-Ol 4.82E-Ol 1.43E-Ol O.OOE+OO 1.2lE-04 6.2SE-Ol 

6.00E-Ol 4.94E-Ol 1.27E-Ol O.OOE+OO 8. 47E-OS 6.2lE-Ol 

7.00E-Ol S.OSE-Ol 1.l3E-0l O.OOE+OO S.98E-OS 6.l8E-Ol 

8.00E-Ol S.14E-Ol 1.OlE-Ol O.OOE+OO 4. 23E-OS 6.l4E-Ol 

9.00E-Ol S.2lE-Ol 8.96E-02 O.OOE+OO 2. 99E-OS 6.llE-0l 

1.OOE+OO S.27E-Ol 7. 97E-02 O.OOE+OO 2.l2E-OS 6.07E-Ol 

2.00E+OO S.4SE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 S.70E-0l 

3.00E+OO S.2SE-Ol 7.l3E-03 O.OOE+OO 3. 82E-08 S.32E-Ol 

4.00E+OO 4.9SE-Ol 2.0SE-03 O.OOE+OO O.OOE+OO 4.97E-Ol 

S.OOE+OO 4.63E-Ol S.8lE-04 O.OOE+OO O.OOE+OO 4. 64E-Ol 

6.00E+OO 4. 33E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO 4.33E-Ol 

7.00E+OO 4.04E-Ol 4.47E-OS O.OOE+OO O.OOE+OO 4.04E-Ol 

8.00E+OO 3.77E-Ol 1.22E-OS O.OOE+OO O.OOE+OO 3.77E-Ol 

9.00E+OO 3.S2E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 3.S2E-Ol 

1.OOE+Ol 3. 28E-Ol 8.96E-07 O.OOE+OO O.OOE+OO 3.28E-Ol 

2.00E+Ol 1. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 64E-Ol 

3.00E+Ol 8.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.20E-02 

4.00E+Ol 4.l0E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l0E-02 

S.OOE+Ol 2.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.0SE-02 

6.00E+Ol 1.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-02 

7.00E+Ol S.13E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.l3E-03 

8.00E+Ol 2.S7E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.S7E-03 

9.00E+Ol 1. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 28E-03 

1.OOE+02 6.4lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.4lE-04 

2.00E+02 .6. 27E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6.27E-07 

B-30 
CLASS D AHAD = 1 HICROII STABLE CHLORINE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

----~-------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1. 99E-03 4.S4E-lO 

2.00E-Ol 4.S6E-03 2. 79E-09 

3.00E-Ol 7. 92E-03 6.9SE-09 

4.00E-Ol 1.llE-02 1.2SE-OS 

S.OOE-Ol 1. 44E-02 1.90E-OS 

6.00E-Ol 1.7SE-02 2. 62E-OS 

7.00E-Ol 2.l2E-02 3. 36E-OS 

S.OOE-Ol 2.4SE-02 4.l3E-OS 

9.00E-Ol 2.S4E-02 4.S9E-OS 

1.OOE+OO 3.20E-02 3.20E-02 S.64E-OS 5. 64E-OS 

2.00E+OO 3.7SE-02 6.9SE-02 S.77E-OS 1.14E-07 

3.00E+OO 3. 72E-02 1.07E-Ol 2. 72E-OS 1.4lE-07 

4.00E+OO 3. 54E-02 1. 42E-Ol 1.lOE-OS 1. 52E-07 

S.OOE+OO 3. 32E-02 1. 75E-Ol O.OOE+OO 1.S7E-07 

6.00E+OO 3.l0E-02 2.06E-Ol O.OOE+OO 1.SSE-07 

7.00E+OO 2.90E-02 2. 35E-Ol O.OOE+OO 1.S9E-07 

S.OOE+OO 2.70E-02 2. 62E-Ol O.OOE+OO 1.S9E-07 

9.00E+OO 2. 52E-02 2.8SE-Ol O.OOE+OO 1.S9E-07 

1.00E+Ol 2. 35E-02 3.11E-0l O.OOE+OO 1.S9E-07 

2.00E+Ol 1.lSE-02 4.7SE-Ol O.OOE+OO 1. 59E-07 

3.00E+Ol 5.S9E-03 S.S7E-Ol O.OOE+OO 1.S9E-07 

4.00E+Ol 2. 94E-03 5. 98E-Ol O.OOE+OO 1.S9E-07 

S.OOE+Ol 1.47E-03 6.l9E-Ol O.OOE+OO 1.S9E-07 

6.00E+Ol 7. 36E-04 6. 29E-Ol O.OOE+OO 1.S9E-07 

7.00E+Ol 3.6SE-04 6. 34E-Ol O.OOE+OO 1.S9E-07 

S.OOE+Ol 1.S4E-04 6. 37E-Ol O.OOE+OO 1.S9E-07 

9.00E+Ol 9.2lE-OS 6. 38E-Ol O.OOE+OO 1.S9E-07 

1.OOE+02 4.60E-OS 6.3SE-Ol O.OOE+OO 1.S9E-07 

2.00E+02 4.S0E-OS 6. 39E-Ol O.OOE+OO 1.S9E-07 

B-31 
CLASS D AHAD "" 1 HICR.OR BALFLIFE= 1.10E+08 DAYS CHLORINE 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 89E-Ol 2. 26E-Ol 3.03E-04 2.l7E-02 6.37E-Ol 

2.00E-Ol 4. 31E-Ol 2.01E-Ol 2. 96E-07 2. 28E-03 6. 34E-Ol 

3.00E-Ol 4.51E-Ol 1.79E-0l O.OOE+OO 4.l5E-04 6.3lE-Ol 

4.00E-Ol 4. 68E-Ol 1.60E-OI O.OOE+OO 1.85E-04 6. 28E-Ol 

5.00E-Ol 4. 82E-Ol l.43E-Ol O.OOE+OO 1.2lE-04 6. 25E-Ol 

6.00E-Ol 4. 94E-Ol l.27E-OI O.OOE+OO 8. 47E-05 6.2lE-01 

7.00E-Ol 5.05E-Ol l.l3E-Ol O.OOE+OO 5. 98E-05 6.l8E-Ol 

8.00E-Ol 5.l4E-Ol 1.OlE-Ol O.OOE+OO 4. 23E-05 6.l4E-Ol 

9.00E-Ol 5.2lE-Ol 8. 96E-02 O.OOE+OO 2.99E-05 6.11E-Ol 

l.OOE+OO 5.27E-Ol 7. 97E-02 O.OOE+OO 2.l2E-05 6.07E-Ol 

2.00E+OO 5. 45E-Ol 2. 42E-02 O.OOE+OO 7.04E-07 5.70E-0l 

3.00E+OO 5. 25E-Ol 7.l3E-03 O.OOE+OO 3. 82E-08 5. 32E-Ol 

4.00E+OO 4.95E-Ol 2.05E-03 O.OOE+OO O.OOE+OO 4.97E-Ol 

5.00E+OO 4. 63E-Ol 5.8lE-;-04 O.OOE+OO O.OOE+OO 4. 64E-Ol 

6.00E+OO 4.33E-Ol l.62E-04 O.OOE+OO O.OOE+OO 4. 33E-01 

7.00E+OO 4.04E-Ol 4. 47E-05 O.OOE+OO O.OOE+OO 4.04E-Ol 

8.00E+OO 3. 77E-Ol 1. 22E-05 O.OOE+OO O.OOE+OO 3. 77E-Ol 

9.00E+OO 3. 52E-Ol ·3. 32E-06 O.OOE+OO O.OOE+OO 3. 52E-Ol .- ~. 1.00E+Ol 3. 28E-0l 8. 96E-07 O.OOE+OO O.OOE+OO 3. 28E-Ol 

2.00E+Ol 1. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 64E-Ol 

3.00E+Ol 8.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.20E-02 

4.00E+Ol 4.l0E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.10E-02 

5.00E+Ol 2.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-02 

6.00E+Ol 1.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-02 

7.00E+Ol 5.13E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5.13E-03 

8.00E+Ol 2. 57E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-03 

9.00E+Ol 1.28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 28E-03 

1.OOE+02 6.4lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.4lE-04 

2.00E+02 6.27E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 27E-07 

B-32 
CLASS D .AMAD - 1 HICROR 1lALl'LI1'E= 1.10B+08 DAYS CBIDRIRB 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1. 99E-03 4. 54E-I0 

2.00E-01 4. 86E-03 2.79E-09 

3.00E-Ol 7. 92E-03 6. 98E-09 

4.00E-Ol 1. 11E-02 1.25E-08 

5.00E-01 1. 44E-02 1.90E-08 

6.00E-Ol 1. 78E-02 2. 62E-08 

7.00E-01 2. 12E-02 3. 36E-08 

8.00E-01 2. 48E-02 4. 13E-08 

9.00E-01 2. 84E-02 4. 89E-08 

1.00E+OO 3.20E-02 3.20E-02 5. 64E-08 5. 64E-08 

2.00E+00 3. 75E-02 6. 95E-02 5.77E-08 1. 14E-07 

3.00E+00 3. 72E-02 1.07E-Ol 2.72E-08 1. 41E-07 

4.00E+00 3. 54E-02 1.42E-Ol 1.IOE-08 1. 52E-07 

5.00E+00 3.~2E-02 1. 75E-Ol O.OOE+OO 1. 57E-07 

6.00E+00 3.10E-02 2.06E-Ol O.OOE+OO 1. 58E-07 

7.00E+00 2.90E-02 2.35E-Ol O.OOE+OO 1.59E-07 

8.00E+00 2.70E-02 2. 62E-Ol O.OOE+OO 1.59E-07 

9.00E+00 2. 52E-02 2. 88E-Ol O.OOE+OO 1. 59E-07 

1.00E+Ol 2. 35E-02 3.11E-01 O.OOE+OO 1. 59E-07 

2.00E+Ol 1. 18E-02 4. 75E-Ol O.OOE+OO 1. 59E-07 

3.00E+Ol 5. 89E-03 5. 57E-Ol O.OOE+OO 1. 59E-07 

4.00E+Ol 2. 94E-03 5. 98E-Ol O.OOE+OO 1. 59E-07 

5.00E+Ol 1.47E-03 6. 19E-Ol O.OOE+OO 1. 59E-07 

6.00E+Ol 7. 36E-04 6.29E-Ol O.OOE+OO 1. 59E-07 

7.00E+Ol 3. 68E-04 6.34E-Ol O.OOE+OO 1. 59E-07 

8.00E+Ol 1. 84E-04 6.37E-Ol O.OOE+OO 1. 59E-07 

9.00E+Ol 9.21E-05 6.38E-Ol O.OOE+OO 1. 59E-07 

1.00E+02 4.60E-05 6.38E-Ol O.OOE+OO 1.59E-07 

2.00E+02 4.50E-08 6.39E-Ol O.OOE+OO 1. 59E-07 

.' \ ',.' 

B-33 
ClASS D AHAD - 1 HICB.OR STABLE POTASSIUM 39 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.91E-Ol 2. 26E-0l 3.03E-04 2.17E-02 6.38E-0l 

2.00E-Ol 4. 34E-Ol 2.01E-Ol 2.96E-07 2. 28E-03 6. 38E-Ol 

3.00E-Ol 4.S7E-Ol 1. 79E-Ol O.OOE+OO 4.lSE-04 6. 36E-Ol 

4.00E-Ol 4.7SE-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 6.3SE-Ol 

S.OOE-Ol 4. 92E-Ol 1. 43E-Ol O.OOE+OO 1.21E-04 6. 34E-Ol 

6.00E-Ol S.06E-Ol 1.27E-Ol O.OOE+OO 8. 47E-OS 6.33E-Ol 

7.00E-Ol S.19E-Ol 1.13E-0l O.OOE+OO S.98E-OS 6.32E-Ol 

8.00E-Ol S.30E-Ol 1.OlE-0l O.OOE+OO 4. 23E-OS 6.31E-Ol 

9.00E-Ol S.40E-Ol 8.96E-02 O.OOE+OO 2. 99E-OS 6.30E-Ol 

1.OOE+OO S.49E-Ol 7. 97E-02 O.OOE+OO 2.l2E-OS 6. 28E-Ol 

2.00E+OO S.9lE-0l 2. 42E-02 O.OOE+OO 7.04E-07 6.lSE-0l 

3.00E+OO S.94E-Ol 7.BE-03 O.OOE+OO 3. 82E-08 6.0lE-0l 

4.00E+OO S.86E-Ol 2.0SE-03 O.OOE+OO O.OOE+OO S.88E-Ol 

S.OOE+OO S.74E-Ol S.8lE-04 O.OOE+OO O.OOE+OO S.74E-Ol 

6.00E+OO S.61E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO S.6lE-Ol 

7.00E+OO S.49E-Ol 4. 47E-OS O.OOE+OO O.OOE+OO S.49E-Ol 

8.00E+OO S.36E-Ol 1.22E-OS O.OOE+OO O.OOE+OO S.36E-Ol 

9.00E+OO S.24E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO S.24E-Ol 

1.OOE+Ol S.12E-Ol 8. 96E-07 O.OOE+OO O.OOE+OO S.12E-Ol 

2.00E+Ol 4.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.07E-Ol 

3.00E+Ol 3.23E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 23E-Ol 

4.00E+Ol 2.S7E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2~S7E-Ol 

5.00E+Ol 2.04E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.04E-0l 

6.00E+Ol 1. 62E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 62E-Ol 

7.00E+Ol 1.29E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.29E-Ol 

8.00E+Ol 1.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-Ol 

9.00E+Ol 8. 13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.13E-02 

1.OOE+02 6. 46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.46E-02 

2.00E+02 6. 48E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 48E-03 

3.00E+02 6.S0E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.S0E-04 

4.00E+02 6. SlE-OS O.OOE+OO O.OOE+OO O.OOE+OO 6.S1E-OS 

5.00E+02 6. 53E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6.S3E-06 

6.00E+02 6.S4E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 54E-07 

7.00E+02 6. 49E-08 O.OOE+OO O.OOE+OO O.OOE+OO 6. 49E-08 

B-34 
ClASS D AHAD = 1 MICROK STABLE POTASSIUH 39 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 6. 63E-04 4. 54E-1O 

2.00E-Ol 1. 62E-03 2. 79E-09 

3.00E-Ol . 2.65E-03 6.98E-09 

4.00E-Ol 3. 72E-03 1. 25E-08 

5.00E-Ol 4. 83E-03 1.90E-08 

6.00E-Ol 5. 98E-03 2. 62E-08 

7.00E-Ol 7.16E-03 3. 36E-08 

8.00E-Ol 8. 36E-03 4. 13E-08 

9.00E-Ol 9. 59E-03 4. 89E-08 

1.00E+00 1.08E-02 1.08E-02 5. 64E-08 5. 64E-08 

2.00E+00 1.32E-02 2. 41E-02 5.77E-08 1. 14E-07 

3.00E+00 1. 37E-02 3.77E-02 2.72E-08 1. 41E-07 

4.00E+00 1. 36E-02 5. 13E-02 1.IOE-08 1.52E-07 

5.00E+00 1. 33E-02 6. 47E-02 O.OOE+OO 1. 57E-07 

6.00E+00 1.31E-02 7.77E-02 O.OOE+OO 1. 58E-07 

7.00E+00 1. 28E-02 9.05E-02 O.OOE+OO 1. 59E-07 

8.00E+00 1. 25E-02 1.03E-Ol O.OOE+OO 1. 59E-07 

9.00E+00 1. 22E-02 1. 15E-Ol O.OOE+OO 1. 59E-07 

1.00E+Ol 1. 19E-02 1. 27E-Ol O.OOE+OO 1. 59E-07 

2.00E+Ol 9.47E-03 2. 32E-Ol O.OOE+OO 1. 59E-07 

3.00E+Ol 7. 52E-03 3. 16E-Ol O.OOE+OO 1. 59E-07 

4.00E+Ol 5. 98E-03 3. 82E-Ol O.OOE+OO 1. 59E-07 

5.00E+Ol 4. 75E-03 4. 35E-Ol O.OOE+OO 1.59E-07 

6.00E+Ol 3. 77E-03 4. 77E-Ol O.OOE+OO 1. 59E-07 

7.00E+Ol 3.00E-03 5.10E-01 O.OOE+OO 1.59E-07 

8.00E+Ol 2. 38E-03 5. 37E-Ol O.OOE+OO 1. 59E-07 

9.00E+Ol 1.89E-03 5. 58E-Ol O.OOE+OO 1.59E-07 

1.00E+02 1.50E-03 5. 75E-Ol O.OOE+OO 1. 59E-07 

2.00E+02 1. 51E-04 6. 33E-Ol O.OOE+OO 1. 59E-07 

3.00E+02 1. 51E-05 6. 38E-Ol O.OOE+OO 1. 59E-07 

4.00E+02 1.52E-06 6.39E-Ol O.OOE+OO 1. 59E-07 

5.00E+02 1. 52E-07 6.39E-Ol O.OOE+OO 1. 59E-07 

6.00E+02 1. 52E-08 6. 39E-01 O.OOE+OO 1. 59E-07 

, " 

B-35 
ClASS D . AHAD - 1 MICRON HALl'LIFE= 4.67E+ll DAYS POrASSIUH 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.91E-01 2.26E-01 3.03E-04 2. 17E-02 6. 38E-01 

2.00E-01 4. 34E-01 2.01E-01 2. 96E-07 2. 28E-03 6. 38E-01 

3.00E-01 4. 57E-01 1. 79E-01 O.OOE+OO 4. 15E-04 6. 36E-01 

4.00E-01 4.75E-01 1.60E-01 O.OOE+OO 1. 85E-04 6. 35E-01 

5.00E-01 4. 92E-01 1.43E-01 O.OOE+OO 1.21E-04 6. 34E-01 

6.00E-01 5.06E-01 1. 27E-01 O.OOE+OO 8.47E-05 6. 33E-01 

7.00E-01 5. 19E-01 1. 13E-01 O.OOE+OO 5. 98E-05 6. 32E-Ol 

8.00E-01 5.30E-01 1.01E-01 O.OOE+OO 4. 23E-05 6. 31E-01 

9.00E-01 5.40E-01 8.96E-02, O.OOE+OO 2. 99E-05 6.30E-01 

1.00E+00 5.49E-01 7. 97E-02 O.OOE+OO 2. 12E-05 6. 28E-01 

2.00E+00 5.91E-01 2.42E-02 O.OOE+OO 7.04E-07 6. 15E-Ol 

3.00E+00 5. 94E-01 7. 13E-03 O.OOE+OO 3. 82E-08 6.01E-Ol 

4.00E+00 5.86E-01 2.05E-03 O.OOE+OO O.OOE+OO 5. 88E-01 

5.00E+00 5. 74E-01 5.81E-04 O.OOE+OO O.OOE+OO 5. 74E-01 

6.00E+00 5.61E-Ol 1.62E-04 O.OOE+OO O.OOE+OO 5. 61E-Ol 

7.00E+00 5.49E-Ol 4. 47E-05 O.OOE+OO O.OOE+OO 5. 49E-01 

8.00E+00 5. 36E-Ol 1. 22E-05 O.OOE+OO O.OOE+OO 5.36E-01 

9.00E+00 5. 24E-01 3. 32E-06 O.OOE+OO O.OOE+OO 5. 24E-01 

1.00E+01 5. 12E-Ol 8.96E-07 O.OOE+OO O.OOE+OO 5. 12E-01 

2.00E+Ol 4.07E-01 O.OOE+OO O.OOE+OO O.OOE+OO 4.07E-01 

3.00E+01 3. 23E-01 O.OOE+oo O.OOE+OO O.OOE+OO 3. 23E-01 

4.00E+01 2. 57E-01 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-Ol 

5.00E+01 2.04E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.04E-01 

6.00E+01 1. 62E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1. 62E-01 

7.00E+01 1.29E-Ol O.OOE+oo O.OOE+OO O.OOE+oo 1. 29E-Ol 

8.00E+01 1.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-01 

9.00E+01 8. 13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 13E-02 

1.00E+02 6.46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 46E-02 

2.00E+02 6. 48E-03 O.OOE+OO O.OOE+OO O.OOE+oo 6. 48E-03 

3.00E+02 6.50E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.50E-04 

4.00E+02 6. 51E-05 O.OOE+OO O.OOE+OO O.OOE+oo 6. 51E-05 

5.00E+02 6. 53E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6. 53E-06 

6.00E+02 6. 54E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 54E-07 

7.00E+02 6. 49E-08 O.OOE+OO O.OOE+OO O.OOE+OO 6. 49E-08 

B-36 
CLASS D AHAD ... 1 HICRON BALPLIPE- 4.67£+11 DAYS POTASSIUII 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 6. 63E-04 4. 54E-I0 

2.00E-Ol 1. 62E-03 2. 79E-09 

3.00E-Ol 2.65E-03 6. 98E-09 

4.00E-Ol 3. 72E-03 1. 25E-08 

5.00E-Ol 4. 83E-03 1.90E-08 

6.00E-Ol 5. 98E-03 2. 62E-08 

7.00E-Ol 7.16E-03 3. 36E-08 

8.00E-Ol 8. 36E-03 4.13E-08 

9.00E-Ol 9.59E-03 4. 89E-08 

1.00E+OO 1.08E-02 1.08E-02 5. 64E-08 5. 64E-08 

2.00E+OO 1. 32E-02 2.41E-02 5.77E-08 1. 14E-07 

3.00E+OO 1. 37E-02 3.77E-02 2.72E-08 1. 41E-07 

4.00E+OO 1. 36E-02 5. 13E-02 1.IOE-08 1. 52E-07 

5.00E+OO 1. 33E-02 6. 47E-02 O.OOE+OO 1. 57E-07 

6.00E+OO 1. 31E-02 7.77E-02 O.OOE+OO 1. 58E-07 

7.00E+OO 1. 28E-02 9.05E-02 O.OOE+OO 1. 59E-07 

8.00E+OO 1.25E-02 1.03E-Ol O.OOE+OO 1. 59E-07 

9.00E+OO 1. 22E-02 1.15E-Ol O.OOE+OO 1. 59E-07 

1.00E+Ol 1. 19E-02 1. 27E-0l O.OOE+OO 1. 59E-07 

2.00E+Ol 9.47E-03 2. 32E-Ol O.OOE+OO 1.59E-07 

3.00E+Ol 7. 52E-03 3. 16E-Ol O.OOE+OO 1. 59E-07 

4.00E+Ol 5. 98E-03 3. 82E-Ol O.OOE+OO 1. 59E-07 

5.00E+Ol 4. 75E-03 4.35E-Ol O.OOE+OO 1. 59E-07 

6.00E+Ol 3.77E-03 4.77E-Ol O.OOE+OO 1. 59E-07 

7.00E+Ol 3.00E-03 5.10E-0l O.OOE+OO 1. 59E-07 

8.00E+Ol 2. 38E-03 5.37E-Ol O.OOE+OO 1. 59E-07 

9.00E+Ol 1.89E-03 5. 58E-0l O.OOE+OO 1. 59E-07 

1.00E+02 1.50E-03 5. 75E-Ol O.OOE+OO 1. 59E-07 

2.00E+02 1. 51E-04 6. 33E-Ol O.OOE+OO 1. 59E-07 

3.00E+02 1.5lE-05 6. 38E-Ol O.OOE+OO 1. 59E-07 

4.00E+02 1. 52E-06 6. 39E-Ol O.OOE+OO 1.59E-07 

5.00E+02 1. 52E-07 6. 39E-Ol O.OOE+OO 1. 59E-07 

6.00E+02 1. 52E-08 6.39E-Ol O.OOE+OO 1. 59E-07 

: - .-

B-37 
CLASS D AHA» = 1 KICllOB STABlB 'l'1TA.BIUH 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-0l 2. 57E-Ol 2.26E-0l 3.03E-04 1. 56E-Ol 6. 39E-Ol 

2.00E-Ol 2. 82E-Ol 2.01E-Ol 2. 96E-07 1. 55E-ol 6.38E-Ol 

3.00E-Ol 3.03E-Ol 1.79E-01 O.OOE+OO 1. S4E-0l 6.36E-Ol 

4.00E-0l 3. 22E-0l 1.60E-01 O.OOE+OO 1.SlE-01 6.33E-Ol 

S.OOE-Ol 3.40E-Ol 1. 43E-0l O.OOE+OO 1. 46E-0l 6. 29E-Ol 

6.00E-Ol 3. 55E-Ol 1.27E-01 O.OOE+OO 1.4lE-01 6.23E-Ol 

7.00E-Ol 3. 69E-Ol 1.13E-01 O.OOE+OO 1.3SE-0l 6.l7E-0l 

8.00E-Ol 3.8lE-01 1.01E-01 O.OOE+OO 1. 28E-Ol 6.l0E-01 

9.00E-Ol 3.92E-0l 8. 96E-02 O.OOE+OO 1.2lE-01 6.02E-Ol 

1.00E+00 4.02E-Ol 7.97E-02 O.OOE+OO 1.14E-01 S.9SE-Ol 

2.00E+00 4.S7E-0l 2. 42E-02 O.OOE+OO 5.l9E-02 5. 33E-Ol 

3.00E+00 4. 73E-Ol 7.13E-03 O.OOE+OO 2.07E-02 5.0lE-Ol 

4.00E+00 4.78E-Ol 2.0SE-03 O.OOE+OO 7.86E-03 4. 88E-Ol 

5.00E+00 4. 79E-Ol 5.8lE-04 O.OOE+OO 2. 93E-03 4. 82E-Ol 

6.00E+00 4.78E-Ol 1. 62E-04 O.OOE+OO 1.09E-03 4.80E-Ol 

7.00E+00 4. 78E-Ol 4. 47E-05 O.OOE+OO 4.00E-04 4. 78E-Ol 

8.00E+OO 4. 78E-Ol 1. 22E-05 O.OOE+OO 1. 47E-04 4. 78E-Ol 

9.00E+00 4.77E-Ol 3. 32E-06 O.OOE+OO 5. 42E-OS 4. 77E-Ol 

1.00E+Ol 4.76E-Ol 8. 96E-07 O.OOE+OO 2.00E-05 4.76E-Ol 

2.00E+Ol 4.11E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.11E-Ol 

3.00E+Ol 4.66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 66E-Ol 

4.00E+Ol 4.60E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.60E-Ol 

5.00E+Ol 4. 55E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.5SE-Ol 

6.00E+Ol 4.50E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.50E-Ol 

7.00E+Ol 4. 45E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.45E-Ol 

6.00E+Ol 4. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 39E-Ol 

9.00E+Ol 4. 34E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 34E-Ol 

1.OOE+02 4. 29E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 29E-Ol 

2.00E+02 3. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.83E-Ol 

3.00E+02 3.4lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.4lE-01 

4.00E+02 3.04E-0l O.OOE+OO O.OOE+OO O.OOE+OO 3.04E-Ol 

5.00E+02 2.7lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 11E-Ol 

6.00E+02 2.41E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2.4lE-Ol 

7.00E+02 2.l5E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.l5E-01 

8.00E+02 1.91E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.91E-Ol 

9.00E+02 1.70E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.70E-Ol :: .' ~ 1.OOE+03 1.S2E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 52E-Ol 

2.00E+03 4. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 78E-02 

4.00E+03 4.75E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.75E-03 

8.00E+03 4. 68E-05 O.OOE+OO O.OOE+OO O.OOE+OO 4. 68E-05 

1.00E+04 4.63E-06 O.OOE+OO O.OOE+OO O.OOE+OO 4.63E-06 

B-38 
CL&SS D AMAD - 1 MICRON STABLE TITANIOH 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 44E-05 6.07E-05 

I 2.00E-Ol 5. 56E-05 7.40E-04 

3.00E-01 8. 94E-05 2. 64E-03 

4.00E-Ol 1. 26E-04 5. 91E-03 

5.00E-Ol 1. 64E-04 1.04E-02 

6.00E-Ol 2.04E-04 1.60E-02 

7.00E-Ol 2. 46E-04 2. 24E-02 

8.00E-Ol 2. 89E-04 2. 92E-02 

9.00E-Ol 3. 34E-04 3. 64E-02 

1.00E+00 3. 79E-04 3. 79E-04 4. 37E-02 4. 37E-02 

2.00E+00 5.02E-04 8. 81E-04 6. 18E-02 1.06E-Ol 

3.00E+00 5. 39E-04 1. 42E-03 3. 12E-02 1.37E-Ol 

4.00E+00 5.50E-04 1. 97E-03 1.28E-02 1.50E-Ol 

5.00E+00 5. 52E-04 2. 52E-03 4. 93E-03 1. 54E-Ol 

6.00E+00 5. 53E-04 3.08E-03 1.85E-03 1. 56E-Ol 

7.00E+00 5. 52E-04 3. 63E-03 6. 85E-04 1. 57E-Ol 

8.00E+00 5. 52E-04 4. 18E-03 2.53E-04 1.57E-Ol 

9.00E+OO 5. 51E-04 4. 73E-03 9.3lE-05 1. 57E-Ol 

1.00E+Ol 5.51E-04 5.28E-03 3.43E-05 1.57E-Ol 

2.00E+01 5. 44E-04 1.08E-02 O.OOE+OO 1. 57E-Ol 

3.00E+Ol 5. 38E-04 1. 62E-02 O.OOE+oo 1. 57E-Ol 

4.00E+Ol 5. 32E-04 2. 15E-02 O.OOE+OO 1. 57E-Ol 

5.00E+01 5. 26E-04 , 2.68E-02 O.OOE+oo 1. 57E-01 

6.00E+Ol 5.20E-04 3.20E-02 O.OOE+OO 1. 57E-Ol 

7.00E+Ol 5. 14E-04 3.72E-02 O.OOE+oo 1.57E-Ol 

8.00E+Ol 5.08E-04 4. 23E-02 O.OOE+OO 1. 57E-Ol 

9.00E+Ol 5.02E-04 4. 73E-02 O.OOE+oo 1. 57E-Ol 

1.00E+02 4. 96E-04 5. 23E-02 O.OOE+OO 1. 57E-Ol 

2.00E+02 4. 42E-04 9. 92E-02 O.OOE+oo 1.57E-Ol 

3.00E+02 3. 94E-04 1. 41E-Ol O.OOE+OO 1. 57E-Ol 

4.00E+02 3. 51E-04 1. 78E-Ol O.OOE+oo 1.57E-Ol 

5.00E+02 3. 13E-04 2. 11E-Ol . O.OOE+OO 1. 57E-Ol 

6.00E+02 2. 79E-04 2.41E-01 O.OOE+oo 1. 57E-Ol 

7.00E+02 2. 48E-04 2. 67E-Ol O.OOE+OO 1. 57E-Ol . ~-' ,.- 8.00E+02 2.21E-04 2.90E-Ol O.OOE+oo 1.57E-Ol 

9.00E+02 1.97E-04 3. 11E-Ol O.OOE+OO 1.57E-01 

1.00E+03 1. 75E-04 3.30E-01 O.OOE+oo 1.57E-01 

2.00E+03 5. 53E-05 4. 34E-Ol O.OOE+OO 1. 57E-ol 

4.00E+03 5. 49E-06 4. 77E-Ol O.OOE+oo 1.57E-Ol 

8.00E+03 5.41E-08 4. 82E-Ol O.OOE+OO 1. 57E-Ol 

9.00E+03 1.70E-08 4. 82E-Ol O.OOE+oo 1.57E-Ol 

B-39 
CLASS D MAD ... 1 MICRON HALJ'LlFE... 3.308+02 DAYS VANADIUH 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-01 2.2lE-01 2.26E-Ol 3.03E-04 1.56E-0l 6.03E-Ol 

2.00E-Ol 2.08E-Ol 2.0lE-01 2. 95E-07 1. 55E-Ol 5. 65E-Ol 

3.00E-Ol 1. 98E-Ol 1. 79E-Ol O.OOE+OO 1.54E-01 5.3lE-01 

4.00E-Ol 1. 89E-Ol 1.60E-01 O.OOE+OO 1.5lE-01 5.00E-OI 

5.00E-Ol 1.83E-01 1.42E-01 O.OOE+OO 1. 46E-Ol 4.7lE-0l 

6.00E-Ol 1.77E-01 1.27E-01 O.OOE+OO 1.4lE-01 4.45E-Ol 

7.00E-Ol 1. 72E-Ol l.l3E-01 O.OOE+OO 1.35E-0l 4.20E-Ol 

8.00E-Ol 1.69E-01 1.00E-01 O.OOE+OO 1. 28E-Ol 3. 97E-Ol 

9.00E-Ol 1.65E-Ol 8. 94E-02 O.OOE+OO 1.21E-0l 3. 75E-Ol 

1.00E+00 1.63E-01 7. 95E-02 O.OOE+OO l.l3E-0l 3. 56E-Ol 

2.00E+00 1.49E-01 2.4lE-02 O.OOE+OO 5. 17E-02 2. 25E-Ol 

3.00E+00 1. 45E-Ol 7.09E-03 O.OOE+OO 2.06E-02 1. 73E-Ol 

4.00E+00 1. 44E-Ol 2.04E-03 O.OOE+OO 7.80E-03 1. 54E-Ol 

5.00E+00 1.43E-01 5. 75E-04 O.OOE+OO 2.90E-03 1.47E-Ol 

6.00E+00 1.43E-Ol 1.60E-04 O.OOE+OO 1.07E-03 1. 44E-0l 

7.00E+00 1.42E-01 4.41E-05 O.OOE+OO 3. 94E-04 1.43E-01 

8.00E+00 1. 42E-Ol 1.20E-05 O.OOE+OO 1. 45E-04 1. 42E-Ol 

9.00E+OO 1.42E-01 3. 26E-06 O.OOE+OO 5. 32E-05 1. 42E-Ol 

1.00E+0l 1.41E-Ol 8. 78E-07 O.OOE+OO 1.95E-05 1.41E-0l 

2.00E+Ol 1. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 38E-Ol 

3.00E+Ol 1. 35E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.35E-01 

4.00E+Ol 1. 33E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 33E-0 

5.00E+Ol 1.30E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.30E 

6.00E+Ol 1.27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 27E-Ol 

7.00E+Ol 1. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-0l 

8.00E+Ol 1.21E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.2lE-OI 

9.00E+Ol 1.19E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 19E-Ol 

1.00E+02 1.16E-OI O.OOE+OO O.OOE+OO O.OOE+OO l.l6E-Ol 

2.00E+02 9. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 36E-02 

3.00E+02 7. 54E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 54E-02 

4.00E+02 6.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.07E-02 

5.00E+02 4. 88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 88E-02 

6.00E+02 3. 93E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 93E-02 

7.00E+02 3.l6E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.l6E-02 

8.00E+02 2. 55E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 55E-02 

9.00E+02 2.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-02 

1.00E+03 l.65E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 65E-02 

2.00E+03 I. 89E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 89E-03 

3.00E+03 2.l5E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2.l5E-04 

4.00E+03 2. 46E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2. 46E-05 

5.00E+03 2.8lE-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.8lE-06 

6.00E+03 3.2lE-07 O.OOE+OO O.OOE+OO O.OOE+OO 3.2lE-07 

7.00E+03 3. 66E-08 O.OOE+OO O.OOE+OO O.OOE+OO 3. 66E-08 

B-40 
CLASS D AMAD .. 1 HICB.OR BALl'Lll'E- 3.30JH02 DAYS VAlIADIUH 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 3. 64E-02 6.07E-05 

2.00E-OI 7. 34E-02 7.40E-04 

3.00E-OI I.05E-0l 2.63E-03 

4.00E-OI I. 33E-ol 5.90E-03 

5.00E-OI I. 57E-Ol I.04E-02 

6.00E-OI 1. 78E-ol 1.60E-02 

7.00E-0l I. 96E-0l 2. 23E-02 

8.00E-Ol 2.12E-Ol 2. 92E-02 

9.00E-Ol 2. 26E-OI 3. 63E-02 

I.OOE+OO 2. 39E-OI 2. 39E-OI 4. 36E-02 4. 36E-02 

2.00E+OO 6.80E-02 3.06E-Ol 6.15E-02 I.05E-0l 

3.00E+OO 2.08E-02 3. 26E-OI 3.lOE-02 1.36E-OI 

4.00E+OO 6. 27E-03 3.32E-Ol I. 27E-02 1.48E-OI 

5.00E+OO 1. 85E-03 3. 33E-Ol 4. 88E-03 1.53E-0l 

6.00E+OO 5. 39E-04 3. 33E-ol 1. 82E-03 1. 54E-Ol 

7.00E+OO 1. 59E-04 3. 32E-Ol 6. 75E-04 1. 55E-Ol 

8.00E+OO 5.15E-05 3. 32E-0l 2. 49E-04 1. 55E-0l 

9.00E+OO 2.13E-05 3.31E-Ol 9.14E-05 l.54E-Ol 

1.OOE+Ol 1.29E-05 3.30E-ol 3. 36E-05 1.54E-Ol 

2.00E+Ol 9. 59E-06 3. 24E-Ol O.OOE+OO 1.51E-0l 

3.00E+0l 9. 38E-06 3.17E-Ol O.OOE+OO I. 48E-0l 

4.00E+OI 9. 18E-06 3.10E-0l O.OOE+OO 1. 45E-Ol 

5.00E+OI 8. 99E-06 3.04E-Ol O.OOE+OO 1. 42E-Ol 

6.00E+Ol 8.79E-06 2. 98E-ol O.OOE+OO 1. 39E-Ol 

7.00E+Ol 8.60E-06 2. 92E-0l O.OOE+OO 1. 36E-Ol 

8.00E+Ol 8. 42E-06 2. 86E-ol O.OOE+OO I. 33E-Ol 

9.00E+Ol 8. 24E-06 2.80E-Ol O.OOE+OO 1.30E-Ol 

I.OOE+02 8.06E-06 2. 74E-Ol O.OOE+OO 1. 28E-Ol 

2.00E+02 6. 49E-06 2. 23E-0l O.OOE+OO I.03E-Ol 

3.00E+02 5. 22E-06 1.8lE-Ol O.OOE+OO 8. 38E-02 

4.00E+02 4.2IE-06 1. 47E-0l O.OOE+OO 6. 79E-02 

5.00E+02 3. 38E-06 1.20E-Ol O.OOE+OO 5.5lE-02 

6.00E+02 2. 72E-06 9. 73E-02 O.OOE+OO 4. 46E-02 

7.00E+02 2.l9E-06 7.9lE-02 O.OOE+OO 3. 62E-02 

8.00E+02 1.77E-06 6. 43E-02 O.OOE+OO 2. 93E-02 

9.00E+02 I. 42E-06 5. 22E-02 O.OOE+OO 2. 38E-02 

·1.OOE+03 1.14E-06 4. 25E-02 O.OOE+OO 1. 93E-02 

2.00E+03 1. 31E-07 5. 33E-03 O.OOE+OO 2. 36E-03 

3.00E+03 1. 49E-08 6. 68E-04 O.OOE+OO 2. 89E-04 

B-41 
CLASS D AHAD = 1 MICR.ON BALFLlm= 2.77£+01 DAYS CHROMIUM 51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-OI 2. SIE-Ol 2.2SE-Ol 3.02E-04 1. SIE-OI 6. 28E-Ol 

2.00E-OI 2. 69E-Ol 2.00E-Ol 2. 94E-07 I.46E-OI 6.lSE-Ol 

3.00E-Ol 2.8IE-OI I.78E-OI O.OOE+OO I.42E-Ol 6.0IE-OI 

4.00E-OI 2.90E-OI 1. S8E-OI O.OOE+OO 1. 37E-Ol S.86E-OI 

S.OOE-OI 2. 97E-OI I.41E-OI O.OOE+OO 1.32E-Ol S.70E-OI 

6.00E-OI 3.02E-OI I.2SE-Ol O.OOE+OO 1. 26E-OI S.S4E-Ol 

7.00E-OI 3.06E-Ol I.HE-OI O.OOE+OO I.20E-Ol S.37E-OI 

8.00E-OI 3.09E-OI 9.87E-02 O.OOE+OO l.l3E-OI S.2IE-Ol 

9.00E-OI 3.IIE-Ol 8.76E-02 O.OOE+OO I.07E-OI S.OSE-Ol 

1.00E+OO 3.12E-Ol 7.77E-02 O.OOE+OO 9. 98E-02 4.S9E-Ol 

2.00E+OO 2. 99E-OI 2.30E-02 O.OOE+OO 4. 42E-02 3.66E-Ol 

3.00E+OO 2.7SE-OI 6. 62E-03 O.OOE+OO 1. 72E-02 2. 98E-OI 

4.00E+OO 2. SIE-Ol 1. 86E-03 O.OOE+OO 6.36E-03 2.60E-OI 

S.OOE+OO 2.3lE-OI S.l2E-04 O.OOE+OO 2.3lE-03 .2. 34E-Ol 

6.00E+OO 2.l3E-OI 1.39E-04 O.OOE+OO 8. 34E-04 2.l4E-OI 

7.00E+OO 1.97E-OI 3.7SE-OS O.OOE+OO 3.00E-04 1. 98E-OI 

S.OOE+OO I.S3E-OI I.OOE-OS O.OOE+OO I.08E-04 1. S3E-Ol 

9.00E+OO 1.71E-Ol 2.6SE .... 06 O.OOE+OO 3. 87E-OS I.71E-Ol 

I.OOE+Ol I.S9E-OI 6.9SE-07 O.OOE+OO 1. 39E-OS 1. S9E-Ol 

2.00E+OI 9.08E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.0SE-02 

3.00E+Ol S.9SE-02 O.OOE+OO O.OOE+OO O.OOE+OO S. 

4.00E+Ol 4.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.20E 

S.OOE+OI 3.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-02 

6.00E+Ol 2.l9E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.19E-02 

7.00E+Ol I.S9E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.S9E-02 

S.OOE+Ol 1.16E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.I6E-02 

9.00E+OI 8. 46E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8. 46E-03 

I.OOE+02 6. 19E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.19E-03 

2.00E+02 2. 93E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 93E-04 

3.00E+02 1. 62E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1. 62E-OS 

4.00E+02 l.02E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-06 

S.OOE+02 7.0SE-08 O.OOE+OO O.OOE+OO O.OOE+OO 7.0SE-OS 

B-42 
CLASS D AHA» = 1 HICRON IlALPLII'E== 2.77B+Ol DAYS ClDtOHIOH .51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 9. 33E-03 S.99E-OS 

2.00E-01 2.02E-02 7. 21E-04 

3.00E-01 3.lOE-02 2. 53E-03 

4.00E-Ol 4. 14E-02 S.62E-03 

S.OOE-Ol S.14E-02 9. 83E-03 

6.00E-01 6.10E-02 1. 49E-02 

7.00E-01 7.01E-02 2.07E-02 

8.00E-01 7. 88E-02 2. 69E-02 

9.00E-01 8. 69E-02 3. 32E-02 

1.00E+OO 9. 46E-02 9. 46E-02 3. 97E-02 3. 97E-02 

2.00E+OO S.76E-02 1.S0E-01 S.32E-02 9. 19E-02 

3.00E+OO 3. 28E-02 1. 79E-01 2.60E-02 1. 16E-ol 

4.00E+OO 2.lOE-02 1.96E-OI 1.04E-02 1. 23E-01 

5.00E+OO l.SSE-02 2.06E-Ol 3. 89E-03 1. 24E-01 

6.00E+OO 1. 26E-02 2. 1 4E-O 1 1. 42E-03 1. 22E-OI 

7.00E+OO 1.07E-02 2.l9E-OI 5.13E-04 1.20E-Ol 

8.00E+OO 9.25E-03 2.23E-01 1.8SE-04 1.17E-01 

9.00E+OO 8.08E-03 2.2SE-01 6. 64E-OS 1. 14E-OI 

1.00E+Ol 7.09E-03 2. 27E-Ol 2. 38E-OS 1.11E-0l 

2.00E+01 2.lOE-03 . 2.lOE-Ol O.OOE+OO 8. 68E-02 

3.00E+01 7.77E-04 1. 74E-01 O.OOE+OO 6. 76E-02 

4.00E+01 3. 79E-04 1.40E-01 O.OOE+OO S.26E-02 

S.OOE+Ol 2. 28E-04 1.I2E-01 O.OOE+OO 4.10E-02 

6.00E+01 ,1. 53E-04 8.87E-02 O.OOE+OO 3. 19E-02 

7.00E",:,OI l.07E-04 7.02E-02 O.OOE+OO 2. 48E-02 

8.00E+01 7.S7E-OS 5. 54E-02 O.OOE+OO l.93E-02 

9.00E+Ol 5.40E-05 4. 37E-02 O.OOE+OO l.51E-02 

l.OOE+02 3. 86E-05 3. 45E-02 O.OOE+OO I.17E-02 

2.00E+02 1.38E-06 3.04E-03 O.OOE+OO 9.60E-04 

3.00E+02 5. 18E-08 2. 57E-04 O.OOE+OO 7. 87E-OS 

B-43 
CLASS D AJW) - 1 MICRON STABLE alROKlDK 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 2. 52E-Ol 2. 26E-Ol 3.03E-04 1.52E-Ol 6.30E-Ol 

2.00E-Ol 2.70E-Ol 2.01E-Ol 2. 96E-07 1. 47E-ol 6.18E-Ol 

3.00E-Ol 2. 83E-Ol 1. 79E-Ol O.OOE+OO 1. 43E-Ol 6.05E-Ol 

4.00E-ol 2. 93E-Ol 1.60E-OI O.OOE+OO 1. 38E-Ol 5. 92E-ol 

5.00E-Ol 3.01E-Ol 1. 43E-Ol O.OOE+OO 1.33E-Ol 5. 77E-Ol 

6.00E-Ol 3.07E-Ol 1. 27E-Ol O.OOE+OO 1. 28E-Ol 5. 62E-Ol 

7.00E-Ol 3.12E-0l 1.13E-0l O.OOE+OO 1. 22E-Ol 5. 47E-Ol 

8.00E-Ol 3.15E-Ol 1.OIE-OI O.OOE+OO 1.16E-Ol 5.31E-ol 

9.00E-Ol 3.18E-0l 8. 96E-02 O.OOE+OO 1.09E-Ol 5.16E-ol 

1.OOE+OO 3. 19E-Ol 7. 97E-02 O.OOE+OO 1.02E-Ol 5.01E-Ol 

·2.00E+OO 3.14E-Ol 2. 42E-02 O.OOE+OO 4. 65E-02 3. 85E-Ol 

3.00E+OO 2. 96E-Ol 7.13E-Q3 O.OOE+OO 1. 85E-02 3. 22E-Ol 

4.00E+OO 2. 78E-Ol 2.05E-03 O.OOE+OO 7.03E-03 2. 87E-0l 

5.00E+OO 2. 62E-Ol 5.81E-04 O.OOE+OO 2. 62E-Q3 2. 65E-Ol 

6.00E+OO 2. 48E-Ol 1.62E-04 O.OOE+OO 9. 69E-04 2. 49E-Ol 

7.00E+OO 2. 35E-Ol 4. 47E-05 O.OOE+OO 3. 57E-04 2. 35E-Ol 

8.00E+OO 2.24E-Ol 1. 22E-05 O.OOE+OO 1. 32E-04 2. 24E-Ol 

9.00E+OO 2. 14E-Ol 3. 32E-06 O.OOE+OO 4. 84E-05 2.14E-ol 

1.OOE+Ol 2.05E-Ol 8. 96E-07 O.OOE+OO 1. 78E-05 2.05E-Ol 

2.00E+Ol 1.50E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.50E-Ol 

3.00E+Ol 1.27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 27E-Ol 

4.00E+Ol 1.14E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.14E-Ol 

5.00E+Ol 1.05E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.05E-OI 

6.00E+Ol 9.80E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.80E-02 

7.00E+Ol 9.16E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 16E-02 

8.00E+Ol 8. 58E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 58E-02 

9.00E+Ol 8.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.04E-02 

1.OOE+02 7.55E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 55E-02 

2.00E+02 4. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 36E-02 

3.00E+02 2. 94E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 94E-02 

4.00E+02 2.-l7E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 27E-02 

5.00E+02 1. 92E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 92E-Q2 

6.00E+02 1.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.71E-02 

7.00E+02 1. 56E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 56E-02 

8.00E+02 1. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 44E-02 

i" 9.00E+02 1. 33E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 33E-02 ." .:~;: :~.:'~':'" 1.OOE+03 1.24E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-02 

2.00E+03 6.20E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.20E-03 

4.00E+03 1. 55E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 55E-03 

8.00E+03 8. 62E-05 O.OOE+OO O.OOE+OO O.OOE+OO 8. 62E-Q5 

1.OOE+04 1.07E-05 O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-05 

B-44 
CLASS D .AHAD .. 1 HICR.ON STABLE aDlOHIUK 52 

TIME AFtER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA. FECES FECES 

1.OOE-Ol 9. 36E-03 6.00E-OS 

2.00E-Ol 2.03E-02 7. 24E-04 

3.00E-Ol 3.12E-02 2.SSE-03 

4.00E-Ol 4.1SE-02 S.67E-03 

S.OOE-Ol S.21E-02 9.9~E-03 

6.00E-Ol 6.19E-02 1.S2E-02 

7.00E-Ol 7.14E-02 2.11E-02 

S.OOE-Ol S.04E-02 2. 74F;-02 

9.00E-Ol S.S9E-02 3.40E-02 

1.OOE+OO 9.70E-02 9.70E-02 4.07E-02 4.07E-02 

2.00E+OO 6.0SE-02 1.SSE-Ol S. S9E-02 9. 66E-02 

3.00E+OO 3.S3E-02 1.93E-Ol 2.S0E-02 1. 25E-Ol 

4.00E+OO 2. 32E-02 2.16E-0l 1.15E-02 1.36E-Ol 

S.OOE+OO 1.7SE-02 2. 34E-Ol 4.41E-03 1.40E-Ol 

6.00E+OO 1.46E-02 2.4SE-Ol 1.6SE-03 1. 42E-0l 

7.00E+OO 1. 27E-02 2.61E-Ol 6.12E-04 1.43E-Ol 

8.00E+OO 1.13E-02 2.nE-Ol 2. 26E-04 1.43E-Ol 

9.00E+OO 1.OlE-02 2.S2E-Ol S.32E-05 I.43E-ol 

I.OOE+OI 9.11E-03 2.91E-0l 3.06E-OS 1.43E-Ol 

2.00E+OI 3. 46E-03 3. 46E-Ol O.OOE+OO 1. 43E-OI 

3.00E+Ol I.6SE-03 3. 69E-Ol O.OOE+OO 1. 43E-0l 

4.00E+OI 1.03E-03 3.S2E-Ol O.OOE+OO 1. 43E-Ol 

S.OOE+Ol 7. 97E-04 3.91E-Ol O.OOE+OO 1.43E-Ol 

6.00E+Ol 6.SSE-04 3.9SE-Ol O.OOE+OO 1. 43E-Ol 

7.00E+Ol 6.15E-04 4.04E-Ol O.OOE+OO 1. 43E-Ol 

S.OOE+Ol S.60E-04 4.lOE-Ol O.OOE+OO 1. 43E-Ol 

9.00E+Ol S.13E-04 4.16E-Ol O.OOE+OO 1.43E-Ol 

1.OOE+02 4. nE-04 4.21E-Ol O.OOE+OO 1.43E-Ol 

2.00E+02 2.06E-04 4.S2E-Ol O.OOE+OO 1. 43E-0l 

3.00E+02 9. 43E-OS 4. 67E-Ol O.OOE+OO 1. 43E-Ol 

4.00E+02 4. 65E-05 4.73E-Ol O.OOE+OO 1. 43E-Ol 

S.OOr.+02 2.S9E-OS 4. 77E-Ol O.OOE+OO 1. 43E-Ol 

6.0f,E+02 1. 67E-05 4.79E-Ol O.OOE+OO 1.43E-Ol 

7.00E+02 1. 24E-OS 4.S0E-Ol O.OOE+OO 1. 43E-Ol .. 

8.00E+02 I.OIE-05 4. 82E-Ol O.OOE+OO 1.43E-Ol 

9.00E+02 S.7SE-06 4. 83E-0l O.OOE+OO 1. 43E-Ol 

1.OOE+03 7.77E-06 4. 84E-Ol O.OOE+OO 1. 43E-Ol 

2.00E+03 2. 27E-06 4.90E-Ol O.OOE+OO 1. 43E-ol 

B-45 
CLASS D AMAD = 1 KICRON STABLE HAHGANESE 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 2.60E-OI 2.26E-OI 3.03E-04 1. S2E-OI 6.38E-OI 

2.00E-OI 2. 87E-OI 2.0IE-OI 2. 96E-07 1.47E-OI 6.3SE-OI 

3.00E-0l 3.lOE-OI 1. 79E-OI O.OOE+OO 1.43E-0l 6. 32E-OI 

4.00E-OI 3. 28E-OI 1.60E-OI O.OOE+OO 1. 38E-OI 6. 26E-OI 

S.OOE-OI 3. 44E-OI 1.43E-OI O.OOE+OO I.33E-OI 6.20E-OI 

6'.OOE-OI 3.S8E-OI 1. 27E-OI O.OOE+OO 1. 28E-OI 6.13E-OI 

7.00E-OI 3.70E-OI 1. 13E-OI O.OOE+OO I.22E-0l 6.0SE-OI 

8.00E-OI 3.80E-OI I.OIE-OI O.OOE+OO 1.16E-OI S.96E-OI 

9.00E-OI 3. 88E-0l 8. 96E-02 O.OOE+OO I.09E-OI S.87E-OI 

I.OOE+OO 3. 96E-OI 7. 97E-02 O.OOE+OO I.02E-OI S.78E-Ol 

2.00E+OO 4. 27E-OI 2. 42E-02 O.OOE+OO 4.6SE-02 4. 98E-OI 

3.00E+OO 4.2IE-OI 7. 13E-03 O.OOE+OO 1.8SE-02 4.47E-OI 

4.00E+OO 4.06E-OI 2.0SE-03 O.OOE+OO 7.03E-03 4. ISE-Ol 

S.OOE+OO 3. 89E-OI S.8IE-04 O.OOE+OO 2. 62E-03 3. 92E-OI 

6.00E+OO 3. 73E-OI I.62E-04 O.OOiHOO 9. 69E-04 3. 74E-OI 

7.00E+OO 3.S8E-OI 4. 47E-OS O.OOE+OO 3.S7E-04 3.S9E-OI 

8.00E+OO 3.4SE-OI 1.22E-OS O.OOE+OO 1. 32E-04 3.4SE-OI 

9.00E+OO 3. 34E-OI 3. 32E-06 O.OOE+OO 4. 84E-oS 3. 34E-OI 

I.OOE+OI 3. 23E-OI 8.96E-07 O.OOE+OO 1. 78E-OS 3. 23E-OI 

2.00E+OI 2.S3E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.S3E-OI 

3.00E+OI 2.09E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.09E-OI 

4.00E+Ol 1.7SE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.7SE-OI 

S.OOE+OI I.47E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.47E-OI 

6.00E+OI 1.24E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.24E-OI 

7.00E+OI I.04E-0l O.OOE+OO O.OOE+OO O.OOE+OO I.04E-OI 

8.00E+OI 8.7SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.7SE-02 

9.00E+OI 7. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 36E-02 

I.OOE+02 6.19E-02 " O.OOE+OO O.OOE+OO O.OOE+OO 6.19E-02 

2.00E+02 I.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.09E-02 

3.00E+02 1. 94E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 94E-03 

4.00E+02 3.42E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-04 

S.OOE+02 6.0SE-OS O.OOE+OO O.OOE+OO O.OOE+OO 6.0SE-OS 

6.00E+02 I.07E-OS O.OOE+OO O.OOE+OO O.OOE+OO I.07E-OS 

7.00E+02 1. 89E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 89E-06 

8.00E+02 3. 34E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3. 34E-07 

9.00E+02 S.83E-08 O.OOE+OO O.OOE+OO O.OOE+OO S.83E-08 

, . 

B-46 
CLASS D AHAD = 1 HICltOtf STABLE MANGANESB 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULAT&D 

DAYS &XCR&TA EXCRETA FECES F&C&S 

1.00E-Ol 1.35&-03 6.00E-05 

2.00&-01 3.09E-03 7.24&-04 

3.00E-Ol 4.97&-03 2.55&-03 

4.00E-Ol 6.97&-03 5. 67E-03 

5.00E-Ol 9.06E-03 9.95&-03 

6.00&-01 1.12&-02 1.52&-02 

7.00&-01 1.35&-02 2. 11E-02 

8.00E-ol 1. 57E-02 2. 74E-02 

9.00E-Ol 1.81&-02 3.40E-02 

1.00&+00 2.04&-02 2.04&-02 4.07&-02 4.07&-02 

2.00&+00 2.42&-02 4.46&-02 5. 59E-02 9.66&-02 

3.00&+00 2.30E-02 6.77E-02 2.80&-02 1.25&-01 

4.00&+00 2.08&-02 8. 84E-02 1.15&-02 1.36&-01 

5.00&+00 1. 84E-02 1.07&-01 4.41E-03 1.40E-Ol 

6.00&+00 1. 63E-02 1.23&-01 1.65E-03 1.42&-01 

7.00&+00 1. 45E-02 1.38&-01 6.12&-04 1.43&-01 

8.00E+00 1.30&-02 1.5lE-0l 2.26&-04 1.43&-01 

9.00E+00 1.17&-02 1. 62E-Ol 8. 32E-05 1.43&-01 

1.00&+01 1.06E-02 1. 73E-Ol 3.06&-05 1.43E-Ol 

2.00&+01 5. 29E-03 2. 43E-Ol O.ooE+OO 1.43&-01 

3.00E+Ol 3.81&-03 2.87&-01 O.OOE+oo 1. 43E-Ol 

4.00E+Ol 3.09&-03 3.21E-Ol O.ooE+OO 1. 43E-Ol 

5.00E+Ol 2.58&-03 3.49E-Ol O.OOE+oo 1.43&-01 

6.00E+Ol 2. 16E-03 3.72&-01 0.00&+00 1. 43E-Ol 

7.00&+01 1.82&-03 3. 92E-Ol 0.00&+00 1.43&-01 

8.00&+01 1.53&-03 4.09&-01 0.00&+00 1. 43E-Ol 

9.00E+Ol 1.29&-03 4.22&-01 0.00&+00 1. 43E-Ol 

1.00&+02 1.08&-03 4.34&-01 0.00&+00 1.43E-Ol 

2.00&+02 1.91&-04 4. 85E-Ol O.OOE+oo 1.43&-01 

3.00&+02 3. 38E-05 4.94&-01 O.OOE+OO 1.43&-01 

4.00&+02 5.98&-06 4.96&-01 0.00&+00 1.43&-01 

5.00&+02 1.06&-06 4.96&-01 O.OOE+OO 1.43&-01 

6.00&+02 1.87E-07 4.96&-01 0.00&+00 1. 43E-Ol 

7.00&+02 3.31&-08 4.96&-01 0.00&+00 1. 43E-Ol '. ':"."", .. 

: .... -.,.: 

B-47 
CLASS D .AHAD - 1 MICRON BALl'LIPE= 3.13E+02 DAYS MANGANtSE 54 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

,.-

I.OOE-Ol 2.60E-Ol 2. 26E-Ol 3.03E-04 1.S2E-Ol 6.38E-0l 

2.00E-Ol 2. 87E-Ol 2.0IE-Ol 2.9SE-07 1.47E-Ol 6.3SE-Ol 

3.00E-0l 3.09E-Ol 1.79E-Ol O.OOE+OO 1. 42E-Ol 6.31E-Ol 

4.00E-0l 3. 28E-Ol 1.60E-Ol O.OOE+OO 1. 38E-Ol 6. 26E-Ol 

5.00E-Ol 3. 44E-Ol 1.42E-Ol O.OOE+OO 1. 33E-0l 6.19E-Ol 

6.00E-0l 3. 57E-Ol 1. 27E-Ol O.OOE+OO 1. 28E-Ol 6.12E-Ql 

7.00E-Ol 3. 69E-Ol 1. 13E-Ol O.OOE+OO 1.22E-Ol 6.04E-Ol 

8.00E-Ol 3. 79E-Ol 1.00E-OI O.OOE+OO 1.lSE-Ol S.95E-Ol 

9.00E-Ol 3. 88E-Ol 8. 94E-02 O.OOE+OO I.09E-Ol 5. 86E-Ol 

I.OOE+OO 3.9SE-OI 7.9SE-02 O.OOE+OO 1.02E-OI 5.77E-Ol 

2.00E+OO 4. 25E-Ol 2.41E-02 O.OOE+OO 4. 63E-02 4. 96E-Ol 

3.00E+OO 4.18E-Ol 7.08E-03 O.OOE+OO 1. 84E-02 4. 44E-0l 

4.00E+OO 4.02E-0l 2.03E-03 O.OOE+OO 6. 96E-03 4.llE-0l 

5.00E+OO 3. 84E-Ol 5-. 74E-04 O.OOE+OO 2.S9E-03 3. 88E-OI 

6.00E+OO 3. 68E-OI 1.60E-04 O.OOE+OO 9.56E-04 3.69E-Ol 

7.00E+OO 3. 53E-OI 4.40E-05 O.OOE+OO 3. 52E-04 3. 53E-0l 

8.00E+OO 3. 39E-Ol I.20E-05 O.OOE+OO 1. 29E-04 3. 39E-Ol 

9.00E+OO 3. 27E-OI 3. 26E-06 O.OOE+OO 4.7SE-05 3.27E-OI 

1.00E+OI 3.16E-Ol 8.77E-07 O.OOE+OO 1. 74E-05 3.I6E-Ol 

2.00E+Ol 2. 42E-ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-OI 

3.00E+Ol 1. 96E-Ol O.OOE+OO O.OOE+OO O.OOE+OO I.96E-OI 

4.00E+OI I.60E-OI O.OOE+OO O.OOE+OO O.OOE+OO I.60E-Ol 

5.00E+OI 1.32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-Ol 

6.00E+Ol 1.08E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.08E-Ol 

7.00E+Ol 8.91E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 91E-02 

8.00E+Ol 7. 33E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 33E-02 

9.00E+OI 6.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.03E-02 

1.OOE+02 4. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 96E-02 

2.00E+02 7.02E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.02E-03 

3.00E+02 9. 95E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 95E-04 

4.00E+02 1.41E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.41E-04 

S.OOE+02 2.00E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.00E-oS 

6.00E+02 2. 83E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 83E-06 

7.00E+02 4.01E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.01E-07 

8.00E+02 S.66E-08 O.OOE+OO O.OOE+OO O.OOE+OO 5. 66E-08 

,',,' , 'I'" 

B-48 
B-49 
CLASS D AHAD - 1 HICltOR BAUUPE ... 9.86E+02 DAYS IRON S5 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.6lE-Ol 2. 26E-Ol 3.03E-04 1.S2E-Ol 6.39E-Ol 

2.00E-Ol 2.90E-Ol 2.0lE-Ol 2. 96E-07 1.47E-Ol 6.3BE-Ol 

3.00E-Ol 3.14E-Ol 1.79E-Ol O.OOE+OO 1. 43E-Ol 6. 36E-Ol 

4.00E-Ol 3.3SE-Ol 1.60E-Ol O.OOE+OO 1.3BE-Ol 6. 33E-Ol 

5.00E-Ol 3. 53E-Ol 1.43E-Ol O.OOE+OO 1. 33E-0l 6.29E-Ol 

6.00E-Ol 3. 69E-Ol 1.27E-Ol O.OOE+OO 1.2BE-Ol 6.24E-Ol 

7.00E-Ol 3.B3E-Ol 1.l3E-Ol O.OOE+OO 1.22E-Ol 6.lBE-Ol 

B.OOE-Ol 3. 95E-Ol 1.OlE-Ol O.OOE+OO 1.16E-Ol 6.l1E-Ol 

9.00E-Ol 4.06E-Ol B.95E-02 O.OOE+OO 1.09E-Ol 6.05E-Ol 

1.OOE+OO 4.l6E-Ol 7. 96E-02 O.OOE+OO 1.02E-Ol S.9BE-Ol 

2.00E+OO 4.71E-Ol 2. 42E-02 O.OOE+OO 4.64E-02 S.4lE-0l 

3.00E+OO 4.B7E-Ol 7.l2E-03 O.OOE+OO 1. BSE-02 S.l3E-Ol 

4.00E+OO 4. 92E-Ol 2.05E-03 O.OOE+OO 7.0lE-03 5.0lE-Ol 

5.00E+OO 4. 93E-Ol 5. 79E-04 O.OOE+OO 2.6lE-03 4. 96E-Ol 

6.00E+OO 4.93E-Ol 1.6lE-04 O.OOE+OO 9.6SE-04 4. 94E-OI 

7.00E+OO 4. 92E-OI 4. 45E-OS O.OOE+OO 3.S6E-04 4. 93E-Ol 

B.OOE+OO 4. 92E-OI 1. 22E-05 O.OOE+OO I.3lE-04 4. 92E-Ol 

9.00E+OO 4.9lE-Ol 3.30E-06 O.OOE+OO 4.BlE-OS 4.9IE-Ol 

1.OOE+Ol 4.9IE-Ol B.90E-07 O.OOE+OO 1.77E-OS 4.9lE-OI 

2.00E+Ol 4.B6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.B6E-Ol 

3.00E+Ol 4.BlE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. BlE-OI 

4.00E+Ol 4. 76E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 76E-OI 

5.00E+Ol 4.7lE-0l O.OOE+OO O.OOE+OO O.OOE+OO 4.7lE-0l 

6.00E+Ol 4. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 66E-Ol 

7.00E+Ol 4.6IE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.6IE-0l 

B.OOE+Ol 4.S6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 56E-Ql 

9.00E+Ol 4.SlE-0l O.OOE+OO O.OOE+OO O.OOE+OO 4.5lE-Ol 

I.OOE+02 4.47E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.47E-Ol 

2.00E+02 4.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.02E-Ol 

3.00E+02 3. 62E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 62E-Ol 

4.00E+02 3.26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 26E-Ol 

S.OOE+02 2. 94E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 94E-Ol 

6.00E+02 2. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 64E-Ol 

7.00E+02 2.3BE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.3BE-OI 

B.OOE+02 2.l4E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.l4E-0l 

9.00E+02 1. 93E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 93E-Ol ... '. 1.OOE+03 1.74E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.74E-0l 

2.00E+03 6.0BE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.0BE-02 

3.00E+03 2.l3E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 13E-02 

4.00E+03 7. 44E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7. 44E-03 

S.OOE+03 2.6lE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.6lE-03 

6.00E+03 9.12E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.l2E-04 

7.00E+03 3.l9E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.l9E-04 

B.OOE+03 1.12E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-04 

9.00E+03 3.9lE-05 O.OOE+OO O.OOE+OO O.OOE+OO 3.9lE-OS 

I.OOE+04 1. 37E-05 O.OOE+OO O.OOE+OO O.OOE+OO 1. 37E-OS 

B-SO 
CLASS D MAD = 1 MICR.ON BALPLIPE= 9.86B+02 DAYS IB.ON SS 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7.36E-06 6.00E-05 

2.00E-Ol 1. 69E-05 7. 24E-04 

3.00E-Ol 2. 74E-05 2. 55E-03 

4.00E-Ql 3. 87E-05 5. 67E-03 

5.00E-Ol 5.06E-05 9.95E-03 

6.00E-Ql 6.3lE-05 1. 52E-02 

7.00E-Ol . 7.6lE-05 2.l0E-02 

8.00E-Ol 8. 96E-OS 2. 74E-02 

9.00E-Ol 1.03E-04 3.40E-02 

1.OOE+OO l.l8E-04 1. 18E-04 4.07E-02 4.07E-02 

2.00E+OO 1.55E-04 2.73E-04 5. 58E-02 9.6SE-02 

3.00E+OO 1. 67E-04 4. 39E-04 2. 79E-02 1. 24E-Ol 

4.00E+OO 1.70E-04 6.09E-04 1.14E-02 1.36E-Ol 

5.00E+OO 1.71E-04 7. 79E-04 4. 39E-Q3 1.40E-Ol 

6.00E+OO 1.71E-04 9. 49E-04 1. 64E-03 1.42E-Ol 

7.00E+OO 1.71E-04 1.12E-03 6.09E-04 1. 42E-Ql 

8.00E+OO 1.70E-04 1. 29E-03 2.2SF;-04 1.42E-Ol 

9.00E+OO 1.70E-04 1. 46E-03 8. 26E-Q5 1.42E-Ol 

1.OOE+Ol 1.70E-04 1. 63E-03 3.04E-OS 1. 42E-0l 

2.00E+Ol 1. 68E-04 3.30E-Q3 O.OOE+OO 1.4lE-Ol 

3.00E+Ol 1.67E-04 4.9SE-03 O.OOE+OO 1.40E-Ol 

4.00E+Ol 1.6SE-04 6.S6E-03 O.OOE+OO 1.39E-OI 

S.OOE+Ol 1.63E-04 8.l5E-03 O.OOE+OO 1. 38E-0l 

6.00E+Ol 1.6lE-04 9. 71E-03 O.OOE+OO 1.37E-Q1 

7.00E+Ol 1.60E-04 1.12E-02 O.OOE+OO 1.36E-Ol 

8.00E+Ol 1. 58E-04 1. 27E-02 O.OOE+OO 1.35E-Ol 

9.00E+Ol 1. 56E-04 1. 42E-02 O.OOE+OO 1. 34E-Ol 

1.OOE+02 1.S5E-04 1.S7E-02 O.OOE+OO 1.33E-Ol 

2.00E+02 1. 39E-04 2. 88E-02 O.OOE+OO 1. 24E-Ol 

3.00E+02 1. 25E-04 3. 96E-02 O.OOE+OO 1.16E-Ol 

4.00E+02 1.13E-04 4. 84E-02 O.OOE+OO 1.08E-Ol 

5.00E+02 1.02E-04 5.5SE-02 O.OOE+OO 1.0lE-Ol 

6.00E+02 9.16E-OS 6.lOE-02 O.OOE+OO 9. 38E-02 

.' 7.00E+02 8.25E-OS 6. 53E-02 O.OOE+OO 8.7SE-02 

8.00E+02 7. 42E-05 6. 84E-02 O.OOE+OO 8.l5E-02 

9.00E+02 6. 68E-05 7.05E-02 O.OOE+OO 7.60E-02 

1.OOE+03 6.02E-05 7.l9E-Q2 O.OOE+OO 7.08E-02 

2.00E+03 2. lIE-OS 6.07E-02 O.OOE+OO 3.5lE-02 

3.00E+03 7.37E-06 3. 89E-02 O.OOE+OO 1. 73E-02 

4.00E+03 2. 58E-06 2. 23E-02 O.OOE+OO 8. 59E-03 

5.00E+03 9.03E-07 1.2lE-02 O.OOE+OO 4. 25E-03 

7.00E+03 1.11E-07 3. 29E-03 O.OOE+OO 1.04E-03 

8.00E+03 3. 87E-08 1. 67E-03 O.OOE+OO 5.l5E-04 

9.00E+03 1. 35E-08 8.4SE-04 O.OOE+OO 2. 55E-04 

B-5l 
CLASS D AMAD = 1 MICRON STABLE IRON 56 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.6lE-Ol 2. 26E-Ol 3.03E-04 1.52E-Ol 6. 39E-Ol 

2.00E-0l 2.90E-Ol 2.01E-Ol 2. 96E-07 1. 47E-Ol 6. 38E-Ol 

3.00E-Ol 3.l4E-Ol 1.79E-0l O.OOE+OO 1. 43E'-Ol 6.37E-Ol 

4.00E-Ol 3.3SE-Ol 1.60E-Ol O.OOE+OO 1. 38E-Ol 6. 33E-Ol 

5.00E-Ol 3. 53E-Ol 1. 43E-Ol O.OOE+OO 1.33E-0l 6. 29E-Ol 

6.00E-Ol 3. 69E-Ol 1.27E-Ol O.OOE+OO 1. 28E-Ol 6.24E-Ol 

7.00E-Ol 3.83E-Ol 1.13E-Ol O.OOE+OO 1.22E-Ol 6.l8E-Ol 

8.00E-Ol 3. 95E-Ol 1.OlE-Ol O.OOE+OO 1. 1 6E-O 1 6.l2E-Ol 

9.00E-Ol 4.06E-Ol 8. 96E-02 O.OOE+OO 1.09E-Ol 6.05E-Ol 

1.OOE+OO 4.l6E-Ol 7. 97E-02 O.OOE+OO 1.02E-Ol 5. 98E-Ol 

2.00E+OO 4.72E-Ol 2. 42E-02 O.OOE+OO 4. 65E-02 S.42E-Ol 

3.00E+OO 4. 88E-Ol 7.l3E-03 O.OOE+OO 1.8SE-02 S.14E-Ol 

4.00E+OO 4. 93E-Ol 2.05E-03 O.OOE+OO 7.03E-03 S.02E-Ol 

5.00E+OO 4.9SE-Ol 5.8lE-04 O.OOE+OO 2. 62E-03 4. 98E-Ol 

6.00E+OO 4.9SE-Ol 1. 62E-04 O.OOE+OO 9.69E-04 4.96E-Ol 

7.00E+OO 4.9SE-Ol 4.47E-OS O.OOE+OO 3.S7E-04 4. 95E-Ol 

8.00E+OO 4.9SE-Ol 1.22E-OS O.OOE+OO 1.32E-04 4.9SE-0l 

9.00E+OO 4.9SE-Ol 3. 32E-06 O.OOE+OO 4.84E-OS 4. 95E-Ol 

1.OOE+Ol 4. 94E-Ol 8.96E-07 O.OOE+OO 1. 78E-OS 4. 94E-Ol 

2.00E+Ol 4. 93E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 93E-Ol 

3.00E+Ol 4.9lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.9lE-Ol 

4.00E+Ol 4.89E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.89E-Ol 

5.00E+Ol 4.88E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 88E-Ol 

6.00E+Ol 4. 86E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 86E-Ol 

7.00E+Ol 4. 84E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 84E-Ol 

8.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.83E-Ol 

9.00E+Ol 4.8lE-0l O.OOE+OO O.OOE+OO O.OOE+OO 4.8lE-0l 

1.OOE+02 4. 79E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 79E-Ol 

2.00E+02 4.63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-Ol 

3.00E+02 4.47E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.47E-Ol 

4.00E+02 -4.32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 32E-Ol 

5.00E+02 4. 17E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.l7E-Ol 

6.00E+02 4.03E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.03E-Ol 

7.00E+02 3. 89E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 89E-Ol 

8.00E+02 3. 76E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.76E-0l 

9.00E+02 3. 63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 63E-Ol , . 1.OOE+03 3.5lE-0l O.OOE+OO O.OOE+OO O.OOE+OO 3.5lE-Ol .. 2.00E+03 2.48E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 48E-Ol 

4.00E+03 1. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-Ol 

8.00E+03 3.lOE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.l0E-02 

1.OOE+04 1. 55E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 55E-02 

2.00E+04 4. 85E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 85E-04 

B-52 
CLASS D AMAD = 1 HICB.OR STABLE IKON 56 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7. 36E-06 6.00E-05 

I 2.00E-Ol 1. 69E-05 7. 24E-04 

3.00E-Ol 2. 74E-05 2.55E-03 

4.00E-Ol 3. 87E-05 5. 67E-03 

5.00E-Ol 5.06E-05 9. 95E-03 

6.00E-Ol 6.31E-05 1. 52E-02 

7.00E-Ol 7. 62E-05 2. 11E-02 

8.00E-Ol 8. 97E-05 2. 74E-02 

9.00E-Ol 1.04E-04 3.40E-02 

1.00E+00 1. 18E-04 1. 18E-04 4.07E-02 4.07E-02 

2.00E+00 1. 56E-04 2. 73E-04 5.59E-02 9. 66E-02 

3.00E+00 1. 67E-04 4.40E-04 2.80E-02 1. 25E-Ol 

4.00E+00 1.70E-04 6. 11E-04 1. 15E-02 1.36E-Ol 

5.00E+00 1. 71E-04 7. 82E-04 4.41E-03 1.40E-Ol 

6.00E+00 1.71E-04 9.53E-04 1.65E-03 1.42E-Ol 

7.00E+00 1.71E-04 1. 12E-03 6. 12E-04 1.43E-Ol 

8.00E+00 1.71E-04 1.30E-03 2.26E-04 1.43E-01 

9.00E+00 1.71E-04 1. 47E-03 8. 32E-05 1. 43E-01 

1.00E+Ol 1.71E-04 1. 64E-03 3.06E-05 1.43E-Ol 

2.00E+Ol 1.71E-04 3. 35E-03 O.OOE+OO 1. 43E-Ol 

3.00E+Ol 1.70E-04 5.05E-03 O.OOE+OO 1. 43E-01 

4.00E+Ol 1.70E-04 6. 75E-03 O.OOE+OO 1.43E-01 

5.00E+Ol 1.69E-04 8. 44E-03 O.OOE+OO 1.43E-Ol 

6.00E+01 1. 68E-04 1.01E-02 O.OOE+OO 1.43E-01 

7.00E+Ol 1.68E-04 1. 18E-02 O.OOE+OO 1. 43E-01 

8.00E+Ol 1. 67E-04 1. 35E-02 O.OOE+OO 1. 43E-01 

9.00E+Ol 1. 67E-04 1.52E-02 O.OOE+OO 1. 43E-01 

1.00E+02 1. 66E-04 1. 68E-02 O.OOE+OO 1. 43E-01 

2.00E+02 1.60E-04 3. 31E-02 O.OOE+OO 1.43E-Ol 

3.00E+02 1. 55E-04 4. 89E-02 O.OOE+OO 1. 43E-Ol 

4.00E+02 1.50E-04 6. 41E-02 O.OOE+OO 1.43E-Ol 

5.00E+02 1. 45E-04 7.88E-02 O.OOE+OO 1.43E-01 

6.00E+02 1.40E-04 9.30E-02 O.OOE+OO 1.43E-01 

7.00E+02 1. 35E-04 1.07E-01 O.OOE+OO 1.43E-01 

8.00E+02 1.30E-04 1.20E-0l O.OOE+OO 1.43E-01 y 9.00E+02 1. 26E-04 1.33E-Ol O.OOE+OO 1. 43E-01 

1.00E+03 1. 22E-04 1.45E-01 O.OOE+OO 1.43E-01 

2.00E+03 8.60E-05 2.48E-Ol O.OOE+OO 1.43E-01 

4.00E+03 4.30E-05 3.72E-01 O.OOE+OO 1. 43E-01 

8.00E+03 1.08E-05 4. 65E-Ol O.OOE+OO 1.43E-01 

1.00E+04 5. 38E-06 4. 81E-0l O.OOE+OO 1.43E-01 

2.00E+04 1. 68E-07 4. 96E-Ol O.OOE+OO 1. 43E-01 

B-53 
CLASS D AMAD - 1 HICR.OI' BALFLII'E- 4.45£+01 DAYS IRON 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 2.6IE-OI 2.25E-OI 3.02E-04 I. 52E-OI 6. 38E-OI 

2.00E-OI 2.S9E-OI 2.0IE-OI 2. 95E-07 1.46E-OI 6.36E-OI 

3.00E-OI 3.13E-OI 1.79E-OI O.OOE+OO 1.42E-OI 6. 34E-Ol 

4.00E-Ol 3.33E-Ol 1. 59E-Ol O.OOE+OO 1.37E-Ol 6. 29E-Ol 

5.00E-OI 3.50E-Ol 1.4IE-Ol O.OOE+OO 1. 32E-OI 6. 24E-Ol 

6.00E-Ol 3. 66E-Ol 1. 26E-Ol O.OOE+OO 1. 27E-Ol 6.l8E-OI 

7.00E-Ol 3. 79E-Ol 1.12E-Ol O.OOE+OO 1.2lE-Ol 6. llE-Ol 

8.00E-Ol 3.90E-Ol 9. 94E-02 O.OOE+OO 1.14E-Ol 6.04E-Ol 

9.00E-Ol 4.0IE-Ol 8.B3E-02 O.OOE+OO 1.07E-Ol 5. 97E-Ol 

1.OOE+OO 4.lOE-Ol 7.B5E-02 O.OOE+OO 1.OIE-Ol 5.B9E-Ol 

2.00E+OO 4. 57E-Ol 2.35E-02 O.OOE+OO 4.5IE-02 5. 26E-Ol 

3.00E+OO 4. 66E-Ol 6. BlE-03 O.OOE+OO 1.77E-02 4.9lE-Ol 

4.00E+OO 4. 64E-Ol 1.93E-03 O.OOE+OO 6.60E-03 4. 72E-Ol 

5.00E+OO 4.5SE-Ol 5. 37E-04 O.OOE+OO 2. 42E-03 4.6lE-Ol 

6.00E+OO 4.5lE-Ol 1.4BE-04 O.OOE+OO B.B3E-04 4.52E-Ol 

7.00E+OO 4. 44E-Ol 4. OlE-OS O.OOE+OO 3.20E-04 4. 44E-Ol 

8.00E+OO 4. 37E-OI 1.OBE-05 O.OOE+OO 1.16E-04 4. 37E-ol 

9.00E+OO 4.30E-OI 2.B9E-06 O.OOE+OO 4.2lE-05 4.30E-Ol 

1.OOE+Ol 4.23E-Ol 7.67E-07 O.OOE+OO 1.53E-05 4. 23E-Ol 

2.00E+Ol 3.6lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.6lE-OI 

3.00E+Ol 3.0SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 3.0BE-Ol 

4.00E+Ol 2. 63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 63E-Ol 

5.00E+Ol 2. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 24E-Ol 

6.00E+Ol 1.9lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.9lE-OI 

7.00E+Ol 1. 63E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.63E-Ol 

B.OOE+Ol 1. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-ol 

9.00E+OI 1.ISE-Ol O.OOE+OO O.OaE+OO O.OOE+OO 1.IBE-Ol 

1.OOE+02 1.OlE-Ol O.OOE+OO , O.OOE+OO O.OOE+OO 1.OIE-Ol 

2.00E+02 2.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.06E-02 

3.00E+02 4.l9E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 19E-03 

4.00E+02 B.54E-04 O.OOE+OO O.OOE+OO O.OOE+OO B.54E-04 

5.00E+02 I. 74E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 74E-04 

6.00E+02 3. 54E-05 O.OOE+OO O.OOE+OO O .. OOE+OO 3. 54E-05 

7.00E+02 7.2lE-06 O.OOE+OO O.OOE+OO O.OOE+OO 7.2lE-06 

B.OOE+02 1.47E-06 O.OOE+OO O.OOE+OO O.OOE+OO I. 47E-06 

9.00E+02 2. 99E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 99E-07 .:: .. '~. ':; " 

I.OOE+03 6.09E-OB O.OOE+OO O.OOE+OO O.OOE+OO 6.09E-08 

B-54 
CLASS D AHAD - 1 MICRON BALPLlFE= 4.45E+Ol DAYS IRON 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7. 35E-06 5.99E-05 

2.00E-Ol 1.69E-05 7. 22E-04 

3.00E-Ol 2.73E-05 2. 54E-03 

4.00E-Ol 3. 84E-05 5. 64E-03 

5.00E-Ol 5.02E-05 9. 88E-03 

6.00E-Ol 6. 25E-05 1.50E-02 

7.00E-Ol 7. 53E-05 2.08E-02 

8.00E-Ol 8. 85E-05 2.71E-02 

9.00E-Ol 1.02E-04 3.35E-02 

1.00E+00 1. 16E-04 1. 16E-04 4.01E-02 4.01E-02 

2.00E+00 1.51E-04 2. 65E-04 5. 42E-02 9. 36E-02 

3.00E+00 1. 59E-04 4.20E-04 2. 67E-02 1. 19E-01 

4.00E+00 1.60E-04 5.74E-04 1.08E-02 1.28E-01 

5.00E+00 1. 58E-04 7. 23E-04 4.08E-03 1.30E-Ol 

6.00E+00 1. 56E-04 8. 68E-04 1.50E-03 1.29E-Ol 

7.00E+00 1. 54E-04 . 1.0IE-03 5. 49E-04 1. 28E-01 

8.00E+00 1.51E-04 1. 14E-03 1.99E-04 1.26E-Ol 

9.00E+00 1.49E-04 1. 28E-03 7. 23E-05 1. 24E-Ol 

1.00E+Ol 1.47E-04 1.40E-03 2. 62E-05 1. 22E-Ol 

2.00E+Ol 1. 25E-04 2. 45E-03 O.OOE+OO 1.05E-Ol 

3.00E+Ol 1.07E-04 3. 17E-03 O.OOE+OO 8.97E-02 

4.00E+Ol 9.10E-05 3. 62E-03 O.OOE+OO 7. 68E-02 

5.00E+Ol 7. 76E-05 3. 88E-03 O.OOE+OO 6. 57E-02 

6.00E+Ol 6. 62E-05 3. 98E-03 O.OOE+OO 5. 62E-02 

7.00E+Ol 5. 64E-05 3. 97E-03 O.OOE+OO 4.81E-02 

8.00E+Ol 4.81E-05 3. 88E-03 O.OOE+OO 4. 12E-02 

9.00E+Ol 4.llE-05 3. 73E-03 O.OOE+OO 3. 53E-02 

1.00E+02 3.50E-05 3. 55E-03 O.OOE+OO 3.02E-02 

2.00E+02 7.13E-06 1.47E-03 O.OOE+OO 6. 36E-03 

3.00E+02 1. 45E-06 4. 58E-04 O.OOE+OO 1. 34E-03 

4.00E+02 2. 96E-07 1.27E-04 O.OOE+OO 2. 83E-04 

5.00E+02 6.03E-08 3. 29E-05 O.OOE+OO 5. 96E-05 

6.00E+02 1. 23E-08 8. 18E-06 O.OOE+OO 1. 26E-05 

. ".-',:',' 

B-55 
CLASS D AHA» = 1 MICRON STABLE NICKEL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2. 22E-Ol 2. 26E-Ol 3.03E-04 1.54E-Ol 6.02E-Ol 

2.00E-Ol 2.llE-Ol 2.01E-Ol 2. 96E-07 1. 52E-Ol 5. 64E-Ol 

3.00E-Ol 2.01E-Ol 1. 79E-Ol O.OOE+OO 1. 49E-0l 5.30E-Ol 

4.00E-Ol 1. 93E-Ol 1.60E-Ol O.OOE+OO 1. 45E-Ol 4. 98E-Ol 

5.00E-Ol 1.86E-Ol 1. 43E-ol O.OOE+OO 1.41E-0l 4.69E-Ol 

6.00E-Ol 1.80E-Ol 1. 27E-Ol O.OOE+OO 1. 35E-Ol 4. 42E-OI 

7.00E-Ol 1.75E-Ol 1.13E-Ol O.OOE+OO 1.29E-Ol 4.17E-0l 

8.00E-Ol 1.7lE-Ol I.OlE-Ol O.OOE+OO 1. 22E-Ol 3. 94E-Ol 

9.00E-Ol 1. 68E-Ol 8. 96E-02 O.OOE+OO l.l6E-0l 3.73E-Ol 

1.OOE+OO 1. 65E-Ol 7. 97E-02 O.OOE+OO 1.09E-Ol 3. 53E-Ol 

2.00E+OO 1.52E-Ol 2. 42E-02 O.OOE+OO 4. 95E-02 2.25E-Ol 

3.00E+OO 1.48E-Ol 7.13E-03 O.OOE+OO 1. 97E-02 1. 75E-Ol 

4.00E+OO 1.47E-Ol 2.05E-03 O.OOE+OO 7. 49E-03 1. 56E-Ol 

5.00E+OO 1.46E-Ol 5.81E-04 O.OOE+OO 2. 79E-03 1.50E-Ol 

6.00E+OO 1.46E-Ol 1.62E-04 O.OOE+OO 1.03E-03 I. 47E-Ol 

7.00E+OO 1.46E-Ol 4. 47E-05 O.OOE+OO 3.8lE-04 1. 46E-Ol 

8.00E+OO 1.46E-Ol 1.22E-05 O.OOE+OO 1.40E-04 1. 46E-Ol 

9.00E+OO 1. 46E";'Ol 3. 32E-06 O.OOE+OO 5. 16E-05 1. 46E-OI 

1.OOE+Ol 1.46E-Ol 8.96E-07 O.OOE+OO 1.90E-05 1.46E-Ol 

2.00E+Ol 1.45E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 45E-Ol 

3.00E+Ol 1. 44E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.44E-Ol 

4.00E+Ol 1.43E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 43E-O 

5.00E+Ol 1. 42E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.42E-Ol 

6.00E+Ol 1.4lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.4lE-Ol 

7.00E+Ol 1.4lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.4lE-Ol 

8.00E+Ol 1.40E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-Ol 

9.00E+Ol 1. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-Ol 

1.OOE+02 1. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 38E-Ol 

2.00E+02 1.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-Ol 

3.00E+02 1.23E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.23E-Ol 

4.00E+02 I. 16E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.16E-Ol 

5.00E+02 1.lOE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.lOE-Ol 

6.00E+02 1.04E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-Ol 

7.00E+02 9. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 78E-02 

8.00E+02 9. 23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 23E-02 

9.00E+02 8.7lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.7lE-02 

., 1.OOE+03 8. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 22E-02 " 2.00E+03 4.6IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.6IE-02 

4.00E+03 1.45E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 45E-02 

8.00E+03 1. 44E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 44E-03 

1.OOE+04 4. 55E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4.55E-04 

2.00E+04 1.42E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 42E-06 

B-56 
CLASS D A!W) == 1 KICR.OH STABLE HICOL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 3. 67E-02 6.04E-05 

2.00E-01 7.43E-02 7. 33E-04 

3.00E-01 1.07E-01 2.60E-03 

4.00E-01 1. 35E-01 5. 81E-03 

5.00E-01 1.60E-01 1.02E-02 

6.00E-01 1.81E-01 1. 56E-02 

7.00E-01 2.00E-01 2. 18E-02 

8.00E-01 2. 16E-01 2. 84E-02 

9.00E-01 2.31E-0l 3. 54E-02 

1.00E+OO 2. 43E-01 2. 43E-01 4. 24E-02 4. 24E-02 

2.00E+OO 6.87E-02 3. 12E-0l 5.92E-02 1.02E-01 

3.00E+OO 2.09E-02 3.33E-01 2. 98E-02 1.31E-01 

4.00E+OO 6. 37E-03 3. 39E-01 1. 22E-02 1.44E-01 

5.00E+OO 1. 94E-03 3.41E-01 4.70E-03 1. 48E-01 

6.00E+OO 6. 18E-04 3. 42E-01 1.76E-03 1. SOE-Ol 

7.00E+OO 2.3SE-04 3.42E-01 6. 52E-04 1.51E-01 

8.00E+OO 1. 26E-04 3. 42E-01 2.41E-04 1.51E-01 

9.00E+OO 9. 58E-05 3.42E-01 8.87E-05 1.SlE-01 

1.00E+01 8.73E-OS 3. 42E-01 3. 26E-05 1.51E-0l 

2.00E+01 8. 36E-OS 3.43E-01 O.OOE+OO 1.51E-01 

3.00E+01 8. 32E-OS 3. 44E-01 O.OOE+OO 1.51E-01 

4.00E+01 8. 27E-OS 3.4SE-01 O.OOE+OO 1.51E-01 

5.00E+01 8. 22E-OS 3. 46E-01 O.OOE+OO 1.SlE-01 

6.00E+01 8. HE-OS 3.47E-01 O.OOE+OO 1.SlE-01 

7.00E+Ol 8. 13E-05 3. 47E-0l O.OOE+OO 1.51E-01 

8.00E+01 8.08E-OS 3. 48E-01 O.OOE+OO 1.51E-01 

9.00E+01 8.03E-05 3. 49E-01 O.OOE+OO 1.SlE-01 

1.00E+02 7. 99E-05 3.50E-01 O.OOE+OO 1. SlE-01 

2.00E+02 7.S4E-05 3.58E-ell O.OOE+OO 1. SlE-Ol 

3.00E+02 7.11E-OS 3. 65E-01 O.OOE+OO 1.SlE-01 

4.00E+02 6.72E-05 3. 72E-01 O.OOE+OO 1. SlE-Ol 

S .. OOE+02 6. 34E-OS 3. 78E-01 O.OOE+OO 1.SlE-01 

6.00E+02 S.98E-OS 3.8SE-01 O.OOE+OO 1. SlE-01 

" , 7.00E+02 S.6SE-OS 3.90E-01 O.OOE+OO 1.SlE-01 

,"" 8.0GE+02 S.33E-OS 3.96E-01 O.OOE+OO 1.SlE-01 

9.00E+02 S.03E-OS 4.01E-01 O.OOE+OO 1.SlE-01 

1.00E+03 4.7SE-OS 4.06E-01 O.OOE+OO 1. SlE-Ol 

2.00E+03 2. 67E-05 4.42E-01 O.OOE+OO 1.SlE-01 

4.00E+03 8.40E-06 4. 74E-01 O.OOE+OO 1.SlE-01 

8.00E+03 8. 42E-07 4.87E-01 O.OOE+OO 1.51E-01 

1.00E+04 2. 73E-07 4. 88E-0l O.OOE+OO 1. SlE-01 

2.00E+04 2.09E-08 4.88E-01 O.OOE+OO 1.51E-01 

B-S7 
CLASS D .AKAD .. 1 MICRON STABLE COPPER. 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 89E-Ol 2.26E-Ol 3.03E-04 1.24E-Ol 6. 39E-Ol 

2.00E-Ol 3. 42E-Ql 2.01E-0l 2. 96E-07 9. 44E-02 6. 38E-Ol 

3.00E-Ol 3. 74E-Ol 1.79E-0l O.OOE+OO 8. 22E-02 6. 36E-Ol 

4.00E-OI 3. 96E-Ol 1.60E-Ol O.OOE+OO 7. 67E-02 6. 33E-Ol 

5.00E-Ol 4.l4E-Ol 1. 43E-Ol O.OOE+OO 7.29E-02 6.29E-0l 

6.00E-OI 4. 29E-OI 1. 27E-0l O.OOE+OO 6. 93E-02 6. 25E-Ql 

7.00E-0l 4. 42E-Ol 1.13E-Ol O.OOE+OO 6. 57E-02 6.2lE-Ol 

8.00E-0l 4. 54E-Ol 1.OlE-Ol O.OOE+OO 6.20E-Q2 6.l6E-Ol 

9.00E-Ol 4.64E-Ol S.96E-02 O.OOE+OO 5. 82E-02 6.l2E-Ol 

1.OOE+OO 4. 73E-Ol 7. 97E-02 O.OOE+OO 5. 44E-02 6.07E-ol 

2.00E+OO 5.20E-Ol 2.42E-02 O.OOE+OO 2. 42E-02 5. 68E-Ol 

3.00E+OO 5. 28E-Ol 7.l3E-03 O.OOE+OO 9. 57E-03 5. 45E-Ol 

4.00E+OO 5. 24E-Ol 2.05E-03 O.OOE+OO 3. 63E-03 5.30E-Ol 

5.00E+OO 5.l6E-Ol 5. 81E-04 O.OOE+OO 1. 35E-03 5.lSE-Ol 

6.00E+OO 5.0SE-Ol 1. 62E-04 O.OOE+OO 4. 99E-04 5.09E-Ol 

7.00E+OO 4. 99E-Ol 4. 47E-05 O.OOE+OO 1. S4E-04 4. 99E-Ol 

S.OOE+OO 4.9lE-Ol 1.22E-05 O.OOE+OO 6.7SE-05 4.9lE-Ol 

9.00E+OO 4.S2E-Ol . 3. 32E-06 O.OOE+OO 2.50E-05 4.S2E-Ol 

1.OOE+Ol 4. 74E-Ol 8. 96E-07 O.OOE+OO 9.lSE-06 4.74E-Ol 

2.00E+Ol 3. 99E-01 O.OOE+OO O.OOE+OO O.OOE+OO 3. 99E-01 

3.00E+Ol 3. 35E-01 O.OOE+OO O.OOE+OO O.OOE+OO 3.35E-01 

4.00E+01 2.S2E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.S2E-O 

5.00E+01 2. 37E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.3 

6.00E+01 1. 99E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 99E-Ol 

7.00E+Ol 1.6SE-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.6SE-0l 

8.00E+01 1.4lE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.41E-Ol 

9.00E+Ol 1. 19E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1. 19E-Ol 

1.OOE+02 9. 97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 97E-02 

2.00E+02 1.76E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.76E-02 

3.00E+02 3. 12E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 12E-03 

4.00E+02 5.51E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5. 51E-04 

5.00E+02 9. 75E-05 O.OOE+OO O.OOE+OO O.OOE+OO 9. 75E-05 

6.00E+02 1.12E-05 O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-05 

7.00E+02 3.05E-06 O.OOE+OO O.OOE+OO O.OOE+OO 3.05E-06 

8.00E+02 5.3SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 5.3SE-07 

1/ 9.00E+02 9. 45E-OS O.OOE+OO O.OOE+OO O.OOE+OO 9. 45E-OS 

I. ,. ., 

. ,; 

.. 1:.00E+03 1.59E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.59E-08 

B-58 
CLASS D AHAD .. 1 HICR.OR STABLE COPPER. 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 3. 86E-04 5. 47E-05 

2.00E-01 9. 36E-04 6.05E-04 

3.00E-01 1. 56E-03 1. 99E-03 

4.00E-01 2. 23E-03 4. 16E-03 

5.00E-01 2.93E-03 6. 97E-03 

6.00E-01 3. 66E-03 1.02E-02 

7.00E-01 4. 41E-03 1. 38E-02 

8.00E-01 5. 19E-03 1. 75E-02 

9.00E-01 5. 99E-03 2. 13E-02 

1.00E+00 6.80E-03 6.80E-03 2. 51E-02 2. 51E-02 

2.00E+00 8. 69E-03 1.55E-02 3.02E-02 5. 53E-02 

3.00E+00 9. 11E-03 2. 46E-02 1. 46E-02 6.99£-02 

4.00E+00 9. 12E-03 3. 37E-02 5.95E-03 7.59E-02 

5.00E+00 9.01£-03 4. 27E-02 2. 28E-03 7. 81E-02 

6.00£+00 8. 87E-03 5.16£-02 8.51E-04 7.90E-02 

7.00E+00 8. 72E-03 6.03E-02 3. 15E-04 7. 93E-02 

8.00E+00 8. 58E-03 6. 89E-02 1. 16E-04 7.94E-02 

9.00E+00 8. 43E-03 7. 73E-02 4. 29E-05 7. 95E-02 

1.00E+01 8. 28E-03 8.56E-02 1.58E-05 7.95E-02 

2.00E+01 6. 97E-03 1.61E-01 O.OOE+OO 7. 95E-02 

3.00E+01 5. 86E-03 2. 24E-01 O.OOE+oo 7.95E-02 

4.00E+01 4. 93E-03 2. 78E-Ol O.OOE+OO 7. 95E-02 

5.00E+01 4. 14E-03 3. 23E-01 O.OOE+oo 7.95E-02 

6.00E+01 3. 48E-03 3.60E-01 O.OOE+OO 7. 95E-02 

7.00E+01 2. 93E-03 3. 92E-01 O.OOE+oo 7. 95E-02 

8.00E+01 2. 46E-03 4. 19E-01 O.OOE+OO 7. 95E-02 

9.00E+01 2.07E-03 4. 41E-01 O.OOE+oo 7. 95E-02 

1.00E+02 1. 74E-03 4.60E-01 O.OOE+OO 7. 95E-02 

2.00E+02 3.08E-04 5. 42E-01 O.OOE+oo 7. 95E-02 

3.00E+02 5. 45E-05 5. 57E-01 O.OOE+OO 7. 95E-02 

4.00E+02 9. 63E-06 5. 59E-01 O.OOE+oo 7.95E-02 

5.00E+02 1.70E-06 5.60E-01 O.OOE+OO 7. 95E-02 

6.00E+02 3.01E-07 5.60E-Ol O.OOE+oo 7. 95E-02 

7.00E+02 5. 33E-08 5.60E-01 O.OOE+OO 7. 95E-02 

B-59 
CLASS D' AMAD - 1 HICB.ON STABLE GALLIUH 69 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 2. 53E-01 2. 26E-01 3.03E-04 1.56E-01 6.35E-01 

2.00E-01 2.71E-01 2.01E-01 2. 96E-07 1. 56E-01 6. 29E-01 

3.00E-01 2.87E-Ol 1. 79E-Ol O.OOE+OO 1.55E-Ol 6.2lE-Ol " 4.00E-Ol 3.00E-Ol 1.60E-Ol O.OOE+OO 1. 52E-Ol 6.l2E-Ol 

5.00E-Ol 3.l2E-0l 1.43E-0l O.OOE+OO 1. 48E-Ol 6.02E-Ol 

6.00E-Ol 3. 22E-01 1.27E-Ol O.OOE+OO 1. 42E-Ol 5.9lE-Ol 

7.00E-Ol 3.30E-Ol 1.l3E-Ol O.OOE+OO 1.36E-Ol 5. 79E-01 

8.00E-Ol 3. 37E-Ol 1.OlE-Ol O.OOE+OO 1.29E-Ol 5. 67E-Ol 

9.00E-Ol 3. 42E-Ol 8. 96E-02 O.OOE+OO 1.22E-Ol 5.54E-Ol 

1.00E+OO 3.47E-Ol 7.97E-02 O.OOE+OO 1. 15E-Ol 5.4lE-Ol 

2.00E+OO 3. S8E-Ol 2. 42E-02 O.OOE+OO 5. 24E-02 4.3SE-Ol 

3.00E+OO 3. 46E-0l 7.l3E-03 O.OOE+OO 2.09E-02 3. 74E-Ol 

4.00E+OO 3. 33E-Ol 2.05E-03 O.OOE+OO 7.95E-03 3. 43E-01 

S.OOE+OO . 3. 23E-Ol S.81E-04 O.OOE+OO 2. 96E-03 3. 26E-Ol 

6.00E+OO 3. 15E-Ol 1.62E-04 O.OOE+OO 1.lOE-03 3.16E-Ol 

7.00E+OO 3.09E-01 4. 47E-OS O.OOE+OO 4.05E-04 3.09E-Ol 

8.00E+OO 3.04E-Ol 1. 22E-OS O.OOE+OO 1. 49E-04 3.04E-Ol 

9.00E+OO 2. 99E-01 3. 32E-06 O.OOE+OO S.48E-OS 2. 99E-Ol 

1.00E+Ol 2.9SE-Ol 8. 96E-07 O.OOE+OO 2.02E-OS 2.9SE-Ol 

2.00E+Ol 2.S6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.S6E-Ol 

3.00E+Ol 2. 23E-Ol O.OOE+OO O.,OOE+OO O.OOE+OO 2.2 

4.00E+Ol 1. 94E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 94E-O 

5.00E+Ol 1. 69E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 69E-01 

6.00E+Ol 1. 47E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 47E-Ol 

7.00E+Ol 1.28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.28E-Ol 

8.00E+Ol 1.12E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-Ol 

9.00E+01 9. 72E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.72E-02 

l.OOE+02 8.46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 46E-02 

2.00E+02 2.l2E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.12E-02 

3.00E+02 S.29E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.29E-03 

4.00E+02 1. 32E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-03 

S.OOE+02 3.3lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.3lE-04 

6.00E+02 8. 28E-OS O.OOE+OO O.OOE+OO O.OOE+OO 8. 28E-OS 

7.00E+02 2.07E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.07E-OS 

8.00E+02 S.17E-06 O.OOE+OO O.OOE+OO O.OOE+OO S.17E-06 

9.00E+02 i.29E-06 O.OOE+OO O.OOE+OO O.OOE+OO i.29E-06 " 1.OOE+03 3. 22E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3. 22E-07 

B-60 
CLASS D AHAD - 1 HICRON STABLE GALLIUH 69 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

hOOE-Ol 4.46E-03 6.07E-05 

2.00E-01 9. 85E-03 7. 42E-04 

3.00E-01 1. 54E-02 2. 64E-03 

4.00E-01 2.lOE-02 5. 93E-03 

5.00E-01 2. 66E-02 1.05E-02 

6.00E-Ol 3. 22E-02 1. 61E-02 

7.00E-0l 3.77E-02 2. 25E-02 

8.00E-01 4. 32E-02 2. 94E-02 

9.00E-Ol 4. 86E-02 3.66E-'02 

1.00E+OO 5. 39E-02 5. 39E-02 4.40E-02 4.40E-02 

2.00E+OO 4. 43E-02 9.81E-02 6.24E-02 1.06E-01 

3.00E+OO 2.90E-02 1. 27E-01 3. 15E-02 1. 38E-01 

4.00E+OO 1.81E-02 1. 45E-Ol 1.30E-02 1. 51E-0l 

5.00E+OO 1. 17E-02 1.57E-Ol 4. 98E-03 1. 56E-01 

6.00E+OO 8.09E-03 1.65E-01 1.87E-03 1. 58E-01 

7.00E+OO 6. 19E-03 1. 11 E-O 1 6. 92E-04 1. 58E-01 

8.00E+OO 5. 19E-03 1. 76E-01 2.56E-04 1.59E-0l 

9.00E+OO 4. 65E-03 1.81E-01 9. 41E-05 1. 59E-01 

1.00E+01 4. 35E-03 1.85E-Ol 3. 47E-05 1. 59E-01 

2.00E+01 3. 58E-03 2. 24E-Ol O.OOE+OO 1. 59E-01 

3.00E+01 3. 12E-03 2. 57E-01 O.OOE+OO 1. 59E-0l 

4.00E+Ol 2.71E-03 2. 86E-01 O.OOE+OO 1. 59E-01 

5.00E+01 2.36E-03 3. l1E-Ol O.OOE+OO 1.59E-01 

6.0(lE+01 2.06E-03 3. 33E-0l O.OOE+OO 1. 59E-Ol 

7.00E+Ol 1. 79E-03 3. 52E-Ol O.OOE+OO 1. 59E-Ol 

8.00E+Ol 1. 56E-03 3. 69E-Ol O.OOE+OO 1. 59E-ol 

9.00E+Ol 1. 36E-03 3. 83E-Ol O.OOE+OO 1. 59E-0l 

1.OOE+02 1. 18E-03 3. 96E-Ol O.OOE+OO 1. 59E-01 

2.00E+02 2.95E-04 4.59E-01 O.OOE+OO 1.59E-01 

3.00E+02 7. 39E-05 4. 75E-01 O.OOE+OO 1. 59E-01 

4.00E+02 1. 85E-05 4.79E-01 O.OOE+OO 1. 59E-01 

5.00E+02 4. 62E-06 4.80E-01 O.OOE+OO 1. 59E-01 

6.00E+02 1. 15E-06 4.80E-01 O.OOE+OO 1. 59E-01 

7.00E+02 2. 89E-07 4.80E-Ol O.OOE+OO 1. 59E-ol 

;";,,< .. 8.00E+02 7.21E-08 4.80E-Ol O.OOE+OO 1. 59E-Ol .... , . 9.00E+02 1. 79E-08 4.80E-Ol O.OOE+OO 1. 59E-01 

B-61 
CLASS D AIWJ - 1 MICRO. STABLE GBRHANlUM 73 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 3. 46E-0l 2. 26E-Ol 3.03E-04 2.l7E-02 S.94E-Ol 

2.00E-Ol 3.35E-Ol 2.0lE-Ol 2. 96E-07 2. 28E-03 S.38E-Ol 

3.00E-0l 3.lOE-0l 1.79E-0l O.OOE+OO 4.1SE-04 4. 89E-0l 

4.00E-Ol 2. 87E-0l 1.60E-Ol O.OOE+OO 1.8SE-04 4. 47E-Ol 

S.OOE-Ol 2. 67E-0l 1. 43E-0l O.OOE+OO 1.2lE-04 4.09E-0l 

6.00E-Ol 2. 49E-0l 1. 27E-Ol O.OOE+OO 8. 47E-oS 3. 76E-Ol 

7.00E-0l 2.33E-Ol 1.13E-Ol O.OOE+OO S.98E-OS ,3.46E-Ol 

8.00E-0l 2. 19E-Ol 1.0lE-OI O.OOE+OO 4. 23E-OS 3. 19E-Ol 

9.00E-Ol 2.06E-Ol 8. 96E-02 O.OOE+OO 2. 99E-OS 2.9SE-0l 

1.00E+OO 1. 94E-Ol 7. 97E-02 O.OOE+OO 2.12E-OS 2. 73E-Ol 

2.00E+OO 1.07E-OI 2. 42E-02 O.OOE+OO 7.04E-07 1.3lE-0l 

3.00E+OO S.73E-02 7.l3E-03 O.OOE+OO 3. 82E-08 6. 44E-02 

4.00E+OO 2. 98E-02 2.0SE-03 O.OOE+OO O.OOE+OO 3.l8E-02 

S.OOE+OO 1.S2E-02 S.8lE-04 O.OOE+OO O.OOE+OO 1.S8E-02 

6.00E+OO 7.69E-03 1.62E-04 o.OOE+dO O.OOE+OO 7.86E-03 

7.00E+OO 3. 87E-03 4. 47E-OS O.OOE+OO O.OOE+OO 3. 92E-03 

8.00E+OO 1.94E-03 1. 22E-OS O.OOE+OO O.OOE+OO 1.96E-03 

9.00E+OO 9. 73E-04 3. 32E-06 O.OOE+OO O.OOE+OO 9.77E-04 

1.OOE+Ol 4. 87E-04 8.96E-07 O.OOE+OO O.OOE+OO 4. 88E-04 

2.00E+Ol 4.77E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.77E-07 

.. " . ~ , .',','. 

B-62 
CLASS D AHA» = I MICRON STABLE GERHAlfIDH 73 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-OI 4. 55E-02 4. 54E-1O 

2.00E-ol I.OIE-OI 2. 79E-09 

3.00E-OI 1.50E-OI 6.9SE-09 

4.00E-Ol I. 92E-Ol I. 25E-OS 

5.00E-0l 2.30E-OI 1.90E-OS 

6.00E-Ol 2. 63E-OI 2. 62E-oS 

7.00E-OI 2 .. 93E-OI 3. 36E-OS 

S.OOE-ol 3.20E-OI 4.13E-OS 

9.00E-OI 3. 44E-OI 4.S9E-OS 

I.OOE+OO 3. 66E-OI 3. 66E-OI 5. 64E-OS 5. 64E-OS 

2.00E+OO 1.42E-OI 5.0SE-OI 5. 77E-OS 1.14E-07 

3.00E+OO 6.6SE-02 5.75E-OI 2. 72E-OS 1.4lE-07 

4.00E+OO 3.26E-02 6.07E-OI 1.IOE-OS I. 52E-OJ 

5.00E+OO 1.60E-02 6. 23E-OI O.OOE+OO I. 57E-07 

6.00E+OO 7. 93E-03 6.3IE-OI O.OOE+OO 1.5SE-07 

7.00E+OO 3. 94E-03 6. 35E-Ol O.OOE+OO 1. 59E-07 

S.OOE+OO 1.96E-03 6. 37E-Ol O.OOE+OO I. 59E-07 

9.00E+OO 9.7SE-04 6. 38E-OI O.OOE+OO I. 59E-07 

I.OOE+OI 4.S9E-04 6. 39E-OI O.OOE+OO I. 59E-07 

2.00E+OI 4.77E-07 6. 39E-OI O.OOE+OO I. 59E-07 

B-63 
CLASS D AMAD "" 1 HICR.ON STABLE SELENIUM 78 

TIME AFTER ,FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3. 38E-OI 2.26E-OI 3.03E-04 7.4IE-02 6.38E-OI 

2.00E-OI 3. 98E-OI 2.0IE-OI 2. 96E-07 3.72E-02 6.37E-OI 

3.00E-OI 4.24E-OI 1.79E-OI O.OOE+OO 3.14E-02 6.3SE-OI 

4.00E-OI 4. 42E-OI 1.60E-OI O.OOE+OO 2. 98E-02 6. 32E-OI 

S.OOE-Ol 4. 58E-OI 1.43E-OI O.OOE+OO 2. 85E-02 6. 29E-OI 

6.00E-Ol 4. 72E-OI I. 27E-OI O.OOE+OO 2.71E-02 6.26E-OI 

7.00E-OI 4.8SE-OI 1.l3E-Ol O.OOE+OO 2. S6E-02 6.23E-OI 

8.00E-OI 4. 96E-OI I.OIE-OI O.OOE+OO 2.4IE-02 6.20E-OI 

9.00E-OI S.OSE-OI 8.96E-02 O.OOE+OO 2.2SE-02 6.17E-OI 

I.OOE+OO S.13E-OI 7. 97E-02 O.OOE+OO 2.IOE-02 6.14E-OI 

2.00E+OO S.53E-OI 2. 42E-02 O.OOE+OO 9. 24E-03 S.86E-OI 

3.00E+OO S.S5E-OI 7.l3E-03 O.OOE+OO 3.ME-03 5. 66E-OI 

4.00E+OO 5. 47E-OI 2.05E-03 O.OOE+OO 1.38E-03 S.50E-OI 

5.00E+OO 5. 36E-OI 5.8IE-04 O.OOE+OO 5.12E-04 5.37E-OI 

6.00E+OO 5. 26E-OI I. 62E-04 O.OOE+OO I. 89E-04 5.26E-OI 

7.00E+OO 5.16E-OI 4. 47E-OS O.OOE+OO 6. 98E-OS 5.16E-OI 

8.00E+OO S.07E-OI I. 22E-05 O.OOE+OO 2. S7E-OS 5.08E-OI 

9.00E+OO 4. 99E-OI 3. 32E-06 O.OOE+OO 9.47E-06 4. 99E-OI 

I.OOE+OI 4. 92E-OI 8. 96E-07 O.OOE+OO 3. 48E-06 4. 92E-OI 

2.00E+OI 4. 32E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4. 32E-OI 

3.00E+OI 3. 87E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3. 87E-OI 

4.00E+Ol 3.50E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3. SOE-ol 

5.00E+0l 3.19E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3.19E-OI 

6.00E+OI 2. 92E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2. 92E-OI 

7.00E+OI 2. 69E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2. 69E-OI 

8.00E+OI 2. 49E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2. 49E-OI 

9.00E+OI 2.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.3IE-OI 

I.OOE+02 2. I 6E-O I O.OOE+OO O.OOE+OO O.OOE+OO 2.16E-OI 

2.00E+02 1.23E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.23E-OI 

3.00E+02 7. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 63E-02 

4.00E+02 4.80E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.80E-02 

S.OOE+02 3.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-02 

6.00E+02 1.90E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.90E-02 

7.00E+02 1.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-02 

8.00E+02 7. 55E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.5SE-03 

9.00E+02 4. 76E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 76E-03 

,', " \ .... I.OOE+03 3.00E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.00E-03 

2.00E+03 2. 95E-05 O.OOE+OO O~OOE+OO O.OOE+OO 2. 95E-05 

3.00E+03 2. 88E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 88E-07 

B-64 
CLASS D AHAD - 1 KIeRON STABI.E SELBRIUH 78 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol B.45E-04 4.16E-05 

2.00E-OI 2.12E-03 3. BOE-04 

3.00E-OI 3.5IE-03 1.IOE-03 

4.00E-OI 4. 96E-03 2.12E-03 

5.00E-OI 6. 45E-03 3. 37E-03 

6.00E-ol 7.9BE-03 4. 75E-03 

7.00E-OI 9. 53E-03 6. 23E-03 

B.OOE-OI 1.IIE~02 7. 75E-03 

9.00E-OI 1. 27E-02 9.27E-03 

I.OOE+OO I. 43E-02 I. 43E-02 I.OBE-02 I.OBE-02 

2.00E+OO 1.60E-02 3.03E-02 l.lBE-02 2. 26E-02 

3.00E+OO 1.49E-02 4. 52E-02 5.60E-03 2.B2E-02 

4.00E+OO 1. 34E-02 5.B6E-02 2. 26E-03 3.04E-02 

5.00E+OO 1.19E-02 7.05E-02 B.64E-04 3.13E-02 

·6.00E+OO I.07E-02 B.12E-02 3.23E-04 3.16E-02 

7.00E+OO 9.70E-03 9.09E-02 1.20E-04 3.17E-02 

B.OOE+OO B.B7E-03 9.9BE-02 4.41E-05 3.IBE-02 

9.00E+OO B.19E-03 I.OBE-Ol 1.63E-05 3.IBE-02 

I.OOE+Ol 7.63E-03 1.16E-Ol 5.9BE-06 3.IBE-02 

2.00E+Ol 5.07E-03 1. 75E-OI O.OOE+OO 3.IBE-02 

3.00E+Ol 4.11E-03 2.20E-OI O.OOE+OO 3.1BE-02 

4.00E+OI 3. 45E-03 2. 57E-OI O.OOE+OO 3.IBE-02 

5.00E+OI 2. 92E-03 2.B9E-OI O.OOE+OO 3.1BE-02 

6.00E+Ol 2.50E-03 3. I 5E-O I O.OOE+OO 3.IBE-02 

7.00E+OI 2.16E-03 3. 39E-0l O.OOE+OO 3.IBE-02 

B.OOE+OI I.BBE-03 3. 59E-Ol O.OOE+OO 3.IBE-02 

9.00E+Ol I. 65E-03 3. 76E-OI O.OOE+OO 3.IBE-02 

I.OOE+02 1. 46E-03 3.91E-Ol O.OOE+OO ,3.IBE-02 

2.00E+02 6.16E-04 4.B4E-OI O.OOE+OO 3.IBE-02 

3.00E+02 3.5BE-04 5.31E-OI O.OOE+OO 3.IBE-02 

4.00E+02 2. 22E-04 5. 59E-Ol O.OOE+OO 3.1BE-02 

5.00E+02 1.40E-04 5. 77E-Ol O.OOE+OO 3.IBE-02 

6.00E+02 B.BIE-05 5.BBE-0l O.OOE+OO 3.IBE-02 

~. / ~: .. 7.00E+02 5. 55E-05 5. 95E-OI O.OOE+OO 3.IBE-02 

B.OdE+02 3.50E-05 6.00E-OI O.OOE+OO 3.1BE-02 

9.00E+02 2.20E-05 6.03E-OI O.OOE+OO 3.IBE-02 

I.OOE+03 1. 39E-05 6.04E-Ol O.OOE+OO 3.1BE-02 

2.00E+03 I. 37E-07 6.07E-OI O.OOE+OO 3.1BE-02 

B-65 
CLASS D AHAD .. 1 MICROB STABLE BROMIBE 79 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 89E-Ol 2. 26E-0l 3.03E-04 2.17E-02 6.37E-Ol 

2.00E-Ol 4.3lE-Ol 2.01E-Ol 2. 96E-07 2. 28E-03 6. 34E-Ol 

3.00E-0l 4.SlE-Ol 1.79E-Ol O.OOE+OO 4.1SE-04 6.3lE-Ol 

4.00E-Ol 4. 68E-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 6. 28E-Ol 

S.OOE-Ol 4. 82E-Ol 1.43E-Ol O.OOE+OO 1.2lE-04 6.2SE-Ol 

6.00E-Ol 4. 94E-Ol 1. 27E-OI O.OOE+OO 8. 47E-OS 6.21E-OI 

7.00E-Ol S.OSE-Ol 1.l3E-OI O.OOE+OO S.98E-OS 6.18E-OI 

8.00E-Ol S.14E-Ol 1.OlE-OI O.OOE+OO 4. 23E-OS 6.14E-Ol 

9.00E-OI S.2IE-Ol 8.96E-02 O.OOE+OO 2. 99E-OS 6. llE-OI 

1.OOE+OO S.27E-Ol 7. 97E-02 O.OOE+OO 2.12E-OS 6.07E-OI 

2.00E+OO S.4SE-0l 2. 42E-02 O.OOE+OO 7.04E-07 S.70E-Ol 

3.00E+OO S.2SE-OI 7.l3E-03 O.OOE+OO 3. 82E-08 S.32E-Ol 

4.00E+OO 4.9SE-Ol 2.0SE-03 O.OOE+OO O.OOE+OO 4.97E-OI 

S.OOE+OO 4. 63E-Ol 5.8lE-04 O.OOE+OO O.OOE+OO 4. 64E-OI 

6.00E+OO 4. 33E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO 4. 33E-Ol 

7.00E+OO 4.04E-OI 4.47E-05 O.OOE+OO O.OOE+OO 4.04E-OI 

8.00E+OO 3.77E-0l 1. 22E-OS O.OOE+OO O.OOE+OO 3. 77E-Ol 

9.00E+OO 3. 52E-OI 3. 32E-06 O.OOE+OO O.OOE+OO 3. 52E-OI 

1.OOE+Ol 3. 28E-Ol 8.96E-07 O.OOE+OO O.OOE+OO 3. 28E-OI 

2.00E+Ol I. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.64E-OI 

3.00E+Ol 8.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.20E-02 

4.00E+Ol 4.10E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.lOE-02 

5.00E+Ol 2.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.0SE-02 

6.00E+Ol 1.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-02 

7.00E+Ol 5.l3E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5.l3E-03 

8.00E+Ol 2. 57E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-03 

9.00E+Ol I. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.28E-03 

1.OOE+02 6.4lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.4IE-04 

2.00E+02 6. 27E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6.27E-07 

B-66 
CLASS D MAD .. 1 MICRON STABLE BROHIHE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 99E-03 4. 54E-I0 

2.00E-Ol 4. 86E-03 2. 79E-09 

3.00E-0l 7. 92E-03 6.98E-09 

4.00E-Ol l.llE-02 1. 25E-08 

5.00E-Ol 1. 44E-02 1.90E-08 

6.00E-Ol 1.78E~02 2. 62E-08 

7.00E-Ol 2. 12E-02 3. 36E-08 

8.00E-Ol 2. 48E-02 4. 13E-08 

9.00E-Ol 2. 84E-02 4. 89E-08 

1.00E+OO 3.20E-02 3.20E-02 5. 64E-08 5. 64E-08 

2.00E+OO 3. 75E-02 6.95E-02 5.77E-08 1. 14E-07 

3.00E+OO 3. 72E-02 1.07E-Ol 2. 72E-08 1. 41E-07 

4.00E+OO 3. 54E-02 1.42E-Ol 1.IOE-08 1. 52E-07 

5.00E+OO 3. 32E-02 1. 75E-Ol O.OOE+OO 1. 57E-07 

6.00E+OO 3.10E-02 2.06E-Ol O.OOE+OO 1. 58E-07 

7.00E+OO 2.90E-02 2. 35E-Ol O.OOE+OO 1. 59E-07 

8.00E+OO 2.70E-02 2. 62E-Ol O.OOE+OO 1.59E-07 

9.00E+OO 2. 52E-02 2. 88E-Ol O.OOE+OO 1. 59E-07 

1.00E+Ol 2. 35E-02 3.llE-Ol O.OOE+OO 1. 59E-07 

2.00E+Ol 1. 18E-02 4. 75E-Ol O.OOE+OO 1. 59E-07 

3.00E+Ol 5. 89E-03 5. 57E-Ol O.OOE+OO 1. 59E-07 

4.00E+Ol 2. 94E-03 5. 98E-Ol O.OOE+OO 1. 59E-07 

5.00E+Ol 1. 47E-03 6. 19E-Ol O.OOE+OO 1.59E-07 

6.00E+Ol 7. 36E-04 6. 29E-Ol O.OOE+OO 1. 59E-07 

7.00E+Ol 3. 68E-04 6. 34E-Ol O.OOE+OO 1. 59E-07 

8.00E+Ol 1. 84E-04 6. 37E-ol O.OOE+OO 1. 59E-07 

9.00E+Ol 9. 21E-05 6. 38E-Ol O.OOE+OO 1. 59E-07 

1.00E+02 4.60E-05 6. 38E-Ol O.OOE+OO 1. 59E-07 

2.00E+02 4.-50E-08 6.39E-Ol O.OOE+OO 1. 59E-07 

B-67 
CI..A.SS D AHAD = 1 KICRON BALl'LIJIB- 1.47B+OO DAYS BROHIRE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 71E-Ol 2.1SE-Ol 2. 89E....;04 2.07E-02 6.08E-Ol 

2.00E-Ol 3. 92E-OI I. 83E-Ol 2. 69E-07 2.08E-03 S.77E-Ol 

3.00E-0l 3. 92E-Ol 1. 56E-Ol O.OOE+OO 3.6IE-04 S.48E-OI 

4. OOE-O I 3. 87E-Ol 1.32E-Ol O.OOE+OO 1. 53E-04 5.20E-Ol 

S.OOE-Ol 3.8lE-01 1.l3E-Ol O.OOE+OO 9. SSE-05 4.94E-Ol 

6.00E-Ol 3. 72E-Ol 9.S7E-02 O.OOE+OO 6. 38E-OS 4. 68E-Dl 

7.00E-Ol 3. 63E-Ol 8.13E-02 O.OOE+OO 4.30E-OS 4.44E-Ol 

8.00E-Ol 3.S2E-Ol 6.90E-02 O.OOE+OO 2.90E-OS 4.2IE-Ol 

9.00E-Ol 3.4lE-01 S.86E-02 O.OOE+OO 1. 96E-OS 4.00E-Ol 

1.00E+00 3. 29E-Ol 4. 97E-02 O.OOE+OO 1. 32E-OS 3. 79E-Ol 

2.00E+00 2.l2E-01 9. 43E-03 O.OOE+OO 2. 74E-07 2. 22E-Ol 

3.00E+00 1. 28E-Ol 1. 73E-03 O.OOE+OO O.OOE+OO 1. 29E-OI 

4.00E+00 7.SlE-02 3.11E-04 O.OOE+OO O.OOE+OO 7. S4E-02 

5.00E+00 4. 38E-02 S.SOE-OS O.OOE+OO O.OOE+OO 4. 39E-02 

6.00E+00 2.S6E-02 9.S7E-06 O.OOE+OO O.OOE+OO 2.S6E-02 

7.00E+00 l.49E-02 1.6S&-06 O.OOE+OO O.OOE+OO 1. 49E-02 

8.00E+00 8. 67E-03 2.8lE-07 O.OOE+OO O.OOE+OO 8. 67E-03 

9.00E+00 S.OSE-03 4.77E-08 O.OOE+OO O.OOE+OO S.OSE-03 

1.00E+Ol 2. 94E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 94E-03 

2.00E+Ol 1. 32E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-OS 

3.00E+Ol S.90E-08 O.OOE+OO O.OOE+OO O.OOE+OO S.90E-08 

I, . 

B-68 
CLASS D AHAD ... 1 MICRON BALFLIFE... 1.47£+00 DAYS BIlOHINE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.90E-03 4.33E-1O 

2.00E-01 4. 42E-03 2. 54E-09 

3.00E-01 6.BBE-03 6.06E-09 

4.00E-01 9.20E-03 1.04E-OB 

5.00E-01 1. 14E-02 1.50E-OB 

6.00E-01 1. 34E-02 1. 97E-OB 

7.00E-01 1.53E-02 2. 42E-OB 

B.OOE-01 1.70E-02 2. 83E-OB 

9.00E-01 1.B6E-02 3.20E-OB 

1.00E+OO 2.00E-02 2.00E-02 3. 52E-OB 3. 52E-OB 

2.00E+OO 1. 46E-02 2. 71E-02 2. 25E-OB 4. 45E-OB 

3.00E+OO 9.04E-03 2. 59E-02 O.OOE+OO 3. 44E-OB 

4.00E+OO 5. 36E-03 2. 16E-02 O.OOE+OO 2. 31E-OB 

5.00E+OO 3. 14E-03 1. 66E-02 O.OOE+OO 1.4BE-OB 

6.00E+OO 1.B3E-03 1. 22E-02 O.OOE+OO 9. 34E-09 

7.00E+OO 1.07E-03 B.67E-03 O.OOE+OO 5.B5E-09 

B.OOE+OO 6. 22E-04 6.03E-03 O.OOE+OO 3.65E-09 

9.00E+OO 3. 62E-04 4. 13E-03 O.OOE+OO 2.2BE-09 

1.00E+01 2. 11E-04 2. 79E-03 O.OOE+OO 1. 42E-09 

2.00E+01 9.44E-07 3.B1E-05 O.OOE+OO 1.2BE-ll 

'.; .. 

B-69 
CLASS D .MIAD - 1 MICRO. STABLE RUBIDIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.9IE-OI 2. 26E-OI 3.03E-04 2.17E-02 6.39E-Ol 

2.00E-OI 4. 34E-OI 2.01E-OI 2. 96E-07 2.2SE-Q3 6.3SE-Ol 

3.00E-Ol 4.S7E-Ol 1. 79E-Ol O.OOE+OO 4.1SE-04 6. 37E-Ol 

4.00E-OI 4. 76E-Ol 1.60E-OI O.OOE+OO 1.SSE-04 6. 37E-Ol 

S.OOE-Ol 4.'93E-Ol 1.43E-Ol O.OOE+OO 1.2IE-04 6. 36E-Ol 

6.00E-OI S.OSE-OI 1. 27E-Ol O.OOE+OO S.47E-05 6.3,SE-Ol 

7.00E-Ol S.2lE-OI 1.l3E-Ol O.OOE+OO S.9SE-OS 6. 34E-Ol 

S.OOE-OI 5. 33E-Ol 1.OlE-OI O.OOE+OO 4. 23E-OS 6. 33E-Ol 

9.00E-OI S.43E-Ol S.96E-02 O.OOE+OO 2. 99E-05 6. 33E-Ol 

1.OOE+OO S.S2E-Ol 7. 97E-02 O.OOE+OO 2.l2E-OS 6. 32E-OI 

2.00E+OO 5.9SE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 6. 23E-OI 

3.00E+OO 6.06E-Ol 7.l3E-03 O.OOE+OO 3.S2E-OS 6. I 3E-O 1 

4.00E+OO 6.0IE-0l 2.0SE-03 O.OOE+OO O.OOE+OO 6.04E-Ol 

5.00E+OO S.94E-Ol S.SlE-04 O.OOE+.OO O.OOE+OO 5. 94E-OI 

6.00E+OO 5.SSE-0l I. 62E-04 O.OOE+OO O.OOE+OO S.SSE .... Ol 

7.00E+OO S.76E-Ol 4. 47E-OS O.OOE+OO O.OOE+OO S.76E-OI 

S.OOE+OO S.67E-Ol 1. 22E-05 O.OOE+OO O.OOE+OO S.67E-Ol 

9.00E+OO S.SSE-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 5.5SE-Ol 

1.OOE+Ol 5.49E-Ol S.96E-07 O.OOE+OO O.OOE+OO 5. 49E-OI 

2.00E+Ol 4. 69E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 69E-Ol 

3.00E+Ol 4.0lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.0lE-Ol 

4.00E+OI 3. 42E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-Ol 

5.00E+Ol 2.92E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 92E-OI 

6.00E+Ol 2.50E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.50E-Ol 

7.00E+Ol 2.l3E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.l3E-OI 

S.UOE+Ol I.S2E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.S2E-OI 

9.00E+Ol 1. 56E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.56E-OI 

I.OOE+02 I. 33E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1. 33E-Ol 

2.00E+02 2.75E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.7SE-02 

3.00E+02 5.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5.70E-03 

4.00E+02 1.ISE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.ISE-03 

5.00E+02 2. 44E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 44E-04 

6.00E+02 5.06E-05 O.OOE+OO O.OOE+OO O.OOE+OO 5.06E-05 

7.00E+02 1.05E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.OSE-OS 

S.OOE+02 2.17E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.l7E-06 

9.00E+02 4.4SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.4SE-07 

'. 1.OOE+03 9.19E-08 O.OOE+OO O.OOE+OO O.OOE+OO 9.19E-OS 

B-70 
ClASS D AHAD == 1 MICRON STABLE RUBIDIOK 85 

TIME. AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 3.40E-04 1. 13E-04 

2.00E-Ol 8. 32E-04 2.77E-04 

3.00E-Ol 1.36E-03 4. 53E-04 

I 4.00E-Ol 1. 91E-03 6. 37E-04 

5.00E-01 2. 48E-03 8. 28E-04 

6.00E-Ol 3.08E-03 1.03E-03 

7.00E-Ol 3.68E-03 1. 23E-03 

8.00E-Ol 4. 31E-03 1. 44E-03 

9.00E-Ol 4. 94E-03 1. 65E-03 

1.00E+00 5. 59E-03 5.598-03 1. 86E-03 1. 86E-03 

2.00E+00 6. 86E-03 1. 24E-02 2. 29E-03 4. 15E-03 

3.00E+00 7.13E-03 1. 96E-02 2. 38E-03 6. 53E-03 

4.00E+00 7. 14E-03 2. 67E-02 2.38E-03 8.90E-03 

5.00E+00 7.06E-03 3. 38E-02 2. 35E-03 1. 13E-02 

6.00E+00 6. 96E-03 4.07E-02 2. 32E-03 1. 36E-02 

7.00E+00 6. 85E-03 4. 76E-02 2. 28E-03 1. 59E-02 

8.00E+00 6.75E-03 5. 43E-02 2. 25E-03 1.81E-02 

9.00E+00 6. 64E-03 6.1OE-02 2. 21E-03 2.03E-02 

1.00E+Ol 6. 54E-03 6. 75E-02 2. 18E-03 2. 25E-02 

2.00E+Ol 5. 59E-03 1. 28E-Ol 1. 86E-03 4. 25E-02 

3.00E+Ol 4. 77E-03 1. 79E-Ol 1. 59E-03 5. 96E-02 

4.00E+Ol 4.08E-03 2. 23E-Ol 1. 36E-03 7. 42E-02 

5.00E+Ol 3. 48E-03 2.60E-Ol 1. 16E-03 8. 67E-02 

6.00E+Ol 2. 97E-03 2. 92E-Ol 9. 92E-04 9. 73E-02 

7.00E+Ol 2. 54E-03 3. 19E-Ol 8. 47E-04 1.06E-Ol 

8.00E+Ol 2.'l7E-03 3. 43E-Ol 7. 24E-04 1. 14E-Ol 

9.00E+Ol 1.85E-03 3. 63E-Ol 6. 18E-04 1.21E-01 

1.00E+02 1. 58E-03 3.80E-Ol 5. 28E-04 1. 27E-Ol 

2.00E+02 3. 28E-04 4. 59E-Ol 1.09E-04 1. 53E-Ol 

3.00E+02 6. 79E-05 4. 75E-Ol 2. 26E-05 1. 58E-Ol 

4.00E+02 1. 41E-05 4. 78E-Ol 4. 68E-06 1.59E-Ol 

5.00E+02 2. 91E-06 4. 79E-01 9.70E-07 1.60E-Ol 

6.00E+02 6.02E-07 4. 79E-Ol 2.01E-07 1.60E-Ol 

7.00E+02 1. 25E-07 4. 79E-Ol 4. 16E-08 1.60E-Ol 

8.00E+02 2. 58E-08 4.79E-Ol O.OOE+OO 1.60E-Ol 

B-71 
CLASS D AHAD ... 1 MICRON BALFLlFE= 6.48E+Ol DAYS STRONTIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1. OOE-O~ 2.40E-01 2. 26E-01 3.02E-04 1.41E-01 6.06E-01 

2.00E-01 2. 68E-01 2.01E-01 2. 95E-07 1. 24E-01 5. 92E-01 

3.00E-01 2. 88E-01 1.79E-01 O.OOE+OO 1. 14E-01 5.81E-01 

4.00E-01 3.03E-01 1. 59E-01 O.OOE+OO 1.08E-01 5.70E-01 

5.00E-01 3.14E-01 1.42E-01 O.OOE+OO 1.03E-01 5. 59E-01 

6.00E-01 3. 23E-01 1.26E-01 O.OOE+OO 9.80E-02 5. 47E-01 

7.00E-01 3.30E-01 1. 12E-01 O.OOE+OO 9. 29E-02 5. 35E-01 

8.00E-01 3. 36E-01 9. 98E-02 O.OOE+OO 8. 77E-02 5. 23E-01 

9.00E-01 3.40E-01 8.87E-02 O.OOE+oo 8. 24E-02 5. 11E-01 

1.00E+OO 3. 44E-01 7. 88E-02 O.OOE+OO 7.71E-02 5.00E-01 

2.00E+00 . 3.41E-01 2. 37E-02 O.OOE+oo 3.43E-02 3. 99E-01 

3.00E+00 3. 12E-01 6.91E-03 O.OOE+OO 1. 34E-02 3. 32E-01 

4.00E+00 2.80E-01 1.97E-03 O.OOE+OO 5.04E-03 2. 87E-01 

5.00E+00 2.51E-01 5.50E-04 O.OOE+OO 1. 86E-03 2. 53E-01 

6.00E+00 2. 26E-01 1.52E-04 O.OOE+oo 6.80E-04 2.27E-01 

7.00E+00 2.05E-01 4. 15E-05 O.OOE+OO 2. 48E-04 2.05E-01 

8.00E+00 1. 87E-01 1. 12E-05 O.OOE+OO 9.04E-05 1. 88E-01 

9.00E+00 1. 72E-01 3.02E-06 O.OOE+OO 3. 29E-05 1. 72E-01 

1.00E+01 1.60E-01 8.06E-07 O.OOE+oo 1.20E-05 1.60E-01 

2.00E+01 9.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.71E-02 

3.00E+01 7. 74E-02 O.OOE+OO O.OOE+OO O.OOE+oo 7.7 

4.00E+01 6.66E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.66E 

5.00E+01 5. 83E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 83E-02 

6.00E+01 5. 13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 13E-02 

7.00E+01 4. 52E-02 O.OOE+OO O.OOE+OO O.OOE+oo 4. 52E-02 

8.00E+01 3. 98E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 98E-02 

9.00E+01 3. 52E-02 O.OOE+oo O.OOE+OO O.OOE+oo 3. 52E-02 

1.00E+02 3. 11E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 11E-02 

2.00E+02 9. 33E-03 O.OOE+oo O.OOE+OO O.OOE+OO 9.33E-03 

3.00E+02 2.91E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 91E-03 

4.00E+02 9.26E-04 O.OOE+OO O.OOE+oo O.OOE+oo 9. 26E-04 

5.00E+02 . 2.99E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 99E-04 

6.00E+02 9. 77E-05 O.OOE+OO O.OOE+OO O.OOE+oo 9. 77E-05 

7.00E+02 3.21E-05 O.OOE+OO O.OOE+OO O.OOE+OO 3. 21E-05 

8.00E+02 1.06E-05 O.OOE+OO O.OOE+oo O.OOE+oo 1.06E-05 

9.00E+02 3. 53E-06 O.OOE+OO O.OOE+OO O.OOE+OO 3. 53E-06 

1.00E+03 1. 18E-06 O.OOE+OO O.OOE+oo O.OOE+oo 1. 18E-06 

B-72 
CLASS D AHAD "" 1 MICRON BALFLlFE- 6.48E+Ol DAYS STRONTIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 2. 74E-02 4.90E-03 

2.00E-Ol 3.S0E-02 7. 39E-03 

3.00E-Ol 4.S4E-02 1.03E-02 

I 4.00E-OI S.ISE-02 1. 42E-02 

S.OOE-OI S.7SE-02 1. SSE-02 

6.00E-OI 6. 36E-02 2.4IE-02 

7.00E-OI 6.9IE-02 2.9SE-02 

S.OOE-OI 7.45E-02 3.SSE-02 

9.00E-Ol 7.97E-02 4.I9E-02 

1.00E+OO S.4SE-02 S.4SE-02 4.S0E-02 4.S0E-02 

2.00E+OO 4.S3E-02 1. 29E-0l S.OOE-02 9.7SE-02 

3.00E+OO 3. 57E-02 1. 64E-OI 2.6SE-02 1. 23E-OI 

4.00E+OO 2.S6E-02 1.90E-Ol 1. 33E-02 1.3SE-0l 

S.OOE+OO 2. 32E-02 2.l2E-Ol 7. 23E-03 1.4lE-Ol 

6.00E+OO I.9lE-02 2. 28E-Ol 4. S3E-03 1.44E-Ol 

7.00E+OO 1.SSE-02 2. 42E-OI 3. 22E-03 1. 46E-Ol 

S.OOE+OO 1. 32E-02 2. S3E-0l 2. 49E-03 1. 47E-0l 

9.00E+OO 1.llE-02 2.6lE-Ol 2.0lE-03 1. 47E-OI 

1.OOE+Ol 9. 33E-03 2.6SE-Ol 1.67E-03 1. 47E-0l 

2.00E+Ol 1.S3E-03 2.S0E-Ol 3. 23E-04 1. 39E-ol 

3.00E+0l 4. S2E-04 2.60E-Ol 7.97E-OS 1.27E-Ol 

4.00E+Ol 1.SOE-04 2. 36E-Ol 3.l7E-OS 1.I4E-Ol 

S.OOE+Ol 1.I4E-04 2.13E-Ol 2. OlE-OS 1.03E-Ol 

6.00E+OI S.SSE-OS 1. 93E-Ol I.57E-OS 9. 26E-02 

7.00E+OI 7.32E-05 1. 74E-Ol 1. 29E-OS S.33E-02 

S.OOE+Ol 6.13E-OS 1.S7E-OI 1.OSE-OS 7.S0E-02 

9.00E+Ol S.16E-OS 1.42E-0l 9.11E-06 6.7SE-02 

l.OOE+02 4.3SE-OS l.2SE-Ol 7.6SE-06 6.07E-02 

2.00E+02 S.S7E-06 4.S0E-02 1.S6E-06 2.11E-02 

3.00E+02 2.0SE-06 l.S7E-02 3. 67E-07 7. 27E-03 

4.00E+02 S.29E-07 5. 45E-03 9. 33E-OS 2. SlE-03 

5.00E+02 l.4lE-07 1. S9E-03 2. 49E-OS S.64E-04 

6.00E+02 3.S7E-OS 6. 52E-04 O.OOE+OO 2.97E-04 

7.00E+02 1.09E-OS 2. 25E-04 O.OOE+OO 1.02E-04 

.I 

B-73 
CLASS D AMAD - 1 MICRON STABLE STRONTIUM 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.40E-Ol 2. 26E-Ol 3.03E-04 1.4lE-Ol 6.07E-OI 

2.00E-Ol 2.6BE-Ol 2.0lE-Ol 2. 96E-07 1. 24E-Ol S.94E-OI 

3.00E-0l 2.B9E-Ol 1. 79E-Ol O.OOE+OO 1.lSE-Ol S.B3E-OI 

4.00E-OI 3.04E-Ol 1.60E-Ol O.OOE+OO 1.OBE-Ol S.73E-Ol 

S.OOE-Ol 3.l6E-Ol 1.43E-Ol O.OOE+OO 1.03E-Ol S.62E-OI 

6.00E-Ol 3.2SE-Ol 1. 27E-Ol O.OOE+OO 9.B6E-02 S.SIE-Ol 

7.00E-Ol 3. 33E-Ol 1.l3E-Ol O.OOE+OO 9.36E-02 S.39E-Ol 

B.OOE-Ol 3. 39E-Ol 1.OIE-Ol O.OOE+OO B.B4E-02 S.2BE-Ol 

9.00E-Ol 3. 44E-Ol B.96E-02 O.OOE+OO B.32E-02 S.16E-Ol 

1.OOE+OO 3. 47E-Ol 7. 97E-02 O.OOE+OO 7. 79E-02 S.OSE-ol 

2.00E+OO 3.4BE-Ol 2. 42E-02 O.OOE+OO 3. SOE-02 4.0BE-Ol 

3.00E+OO 3. 22E-Ol 7.l3E-03 O.OOE+OO 1. 39E-02 3. 43E-Ol 

4.00E+OO 2. 92E-Ol 2.0SE-03 O.OOE+OO S.26E-03 2.99E-0l 

S.OOE+OO 2.6SE-Ol S.BlE-04 O.OOE+OO 1. 96E-03 2. 67E-Ol 

6.00E+OO 2.4lE-Ol 1.62E-04 O.OOE+OO 7.2SE-04 2. 42E-Ol 

7.00E+OO 2.2lE-Ol 4.47E-OS O.OOE+OO 2.67E-04 2.2lE-0i 

B.OOE+OO 2.04E-Ol 1. 22E-OS O.OOE+OO 9. BSE-OS 2.04E-Ol 

9.00E+OO 1.90E-Ol 3. 32E-06 O.OOE+OO 3. 63E-OS 1.90E-Ol 

1.OOE+Ol 1.7BE-Ol B.96E-07 O.OOE+OO 1.33E-OS 1.7BE-Ol 

2.00E+Ol 1.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-Ol 

3.00E+Ol 1.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-Ol 

4.00E+Ol 1.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-O 

S.OOE+Ol 9.94E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.94E 

6.00E+Ol 9. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 73E-02 

7.00E+Ol 9. SSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.SSE-02 

B.OOE+Ol 9. 37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 37E-02 

9.00E+Ol 9.2lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.2lE-02 

1.OOE+02 9.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.0SE-02 

2.00E+02 7.9lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.9lE-02 

3.00E+02 7.lBE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.l8E-02 

4.00E+02 6. 67E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 67E-02 

S.OOE+02 6. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 27E-02 

6.00E+02 S.96E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.96E-02 

7.00E+02 5.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.71E-02 

8.00E+02 S.50E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.SOE-02 

9.00E+02 S.32E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.32E-02 \, . 1.OOE+03 S.17E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.17E-02 

2.00E+03 4.lSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.lSE-02 

4.00E+03 2. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 96E-02 

B.OOE+03 1.7BE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 78E-02 

1.OOE+04 1. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 44E-02 

2.00E+04 S.9lE-03 O.OOE+OO O.OOE+OO O.OOE+OO S.9lE-03 

B-74 
ClASS D .AHAD - 1 MICRON STABLE SDORTIOH 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 2. 75E-02 4. 91E-03 

2.00E-Ol 3. 81E-02 7.41E-03 

3.00E-Ol 4. 55E-02 1.04E-02 

4.00E-Ol 5.21E-02 1. 42E-02 

5.00E-Ol 5. 82E-02 1. 89E-02 

6.00E-Ol 6.40E-02 2. 43E-02 

7.00E-Ol 6.96E-02 3.00E-02 

8.00E-Ol 7.51E-02 3. 61E-02 

9.00E-Ol 8.05E-02 4. 23E-02 

1.00E+OO 8. 57E-02 8. 57E-02 4. 85E-02 4. 85E-02 

2.00E+00 4. 63E-02 1. 32E-Ol 5. 11E-02 9. 96E-02 

3.00E+00 3. 69E-02 1. 69E-Ol 2. 76E-02 1. 27E-Ol 

4.00E+00 2. 98E-02 1.99E-Ol 1. 39E-02 1.41E-Ol 

5.00E+OO 2. 45E-02 2. 23E-Ol 7. 63E-03 1. 49E-Ol 

6.00E+00 2.04E-02 2. 44E-Ol 4. 83E-03 1. 54E-Ol 

7.00E+OO 1. 71E-02 2. 61E-ol 3. 47E-03 . 1.57E-01 

8.00E+00 1. 44E-02 2.75E-Ol 2.71E-03 1.60E-01 

9.00E+00 1. 22E-02 2. 87E-Ol 2. 22E-03 1. 62E-Ol 

1.00E+Ol 1.04E-02 2. 98E-01 1. 86E-03 1. 64E-Ol 

2.00E+Ol 2. 27E-03 3. 46E-Ol 4.00E-04 1. 72E-Ol 

3.00E+Ol 6. 22E-04 3. 58E-Ol 1.1OE-04 1. 74E-01 

4.00E+Ol 2. 76E-04 3. 62E-Ol 4. 87E-05 1. 75E-Ol 

5.00E+Ol 1. 95E-04 3. 64E-Ol 3. 43E-05 1.76E-Ol 

6.00E+Ol 1. 69E-04 3. 66E-Ol 2. 98E-05 1.76E-ol 

7.00E+Ol 1. 55E-04 3. 68E-Ol 2. 73E-05 1. 76E':"01 

8.00E+Ol 1. 44E-04 3. 69E-Ol 2. 54E-05 1. 76E-Ol 

9.00E+Ol 1.35E-04 3.70E-Ol 2. 38E-05 1.77E-Ol 

1.00E+02 1. 27E-04 3. 72E-Ol 2. 24E-05 1. 77E-Ol 

2.00E+02 7. 52E-05 3. 81E-ol 1. 33E-05 1.79E-Ol 

3.00E+02 5. 14E-05 3. 88E-Ol 9.06E-06 1.80E-Ol 

4.00E+02 3-';80E-05 3. 92E-Ol 6.71E-06 1.80E-Ol 

5.00E+02 2. 95E-05 3. 95E-Ol 5. 21E-06 1.81E-ol 

6.00E+02 2. 36E-05 3. 98E-Ol 4. 17E-06 1.82E-Ol 

7.00E+02 1. 94E-05 4.00E-Ol 3. 43E-06 1. 82E-Ol 

8.00E+02 1. 64E-05 4.02E-Ol 2. 89E-06 1. 82E-01 

9.00E+02 1. 41E-05 4.03E-ol 2. 49E-06 1. 82E-ol ; '" 1.00E+03 1.24E-05 4.05E-Ol 2. 19E-06 1. 83E-Ol 

2.00E+03 6. 66E-06 4. 13E-Ol 1. 18E-06 1. 84E-01 

4.00E+03 3. 81E-06 4. 23E-01 6.73E-07 1. 86E-Ol 

8.00E+03 1. 66E-06 4. 34E-Ol 2. 92E-07 1. 88E-01 

1.00E+04 1.22E-06 4. 36E-Ol 2. 15E-07 1. 88E-Ol 

2.00E+04 4. 28E-07 4. 44E-01 7. 56E-08 1.90E-Ol 

B-75 
CLASS D AMAD = 1 MICRON BALFLIFE= 1.06£+04 DAYS STRONTIUM 90 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2.40E-01 2. 26E-01 3.03E-04 1. 41E-01 6.07E-Ol 

2.00E-01 2. 68E-01 2.01E-01 2. 96E-07 1. 24E-01 5. 94E-01 

3.00E-Ol 2. 89E-01 1. 79E-01 O.OOE+OO 1. 15E-Ol 5.83E-01 

4.00E-01 3.04E-01 1.60E-01 O.OOE+OO 1.08E-Ol 5. 73E-Ol 

5.00E-01 3. 16E-01 1.43E-01 O.OOE+OO 1.03E-01 5.62E-01 

6.00E-01 3. 25E-01 1.27E-01 O.OOE+OO 9. 86E-02 5.51E-01 

7.00E-01 3. 33E-01 1. 13E-01 O.OOE+OO 9.36E-02 5.39E-01 

8.00E-01 3. 39E-01 1.01E-01 O.OOE+OO 8. 84E-02 5.28E-01 

9.00E-01 3. 44E-01 8.96E-02 O.OOE+OO 8. 32E-02 5. 16E-01 

1.00E+00 3. 47E-01 7. 97E-02 O.OOE+OO 7. 79E-02 5.05E-01 

2.00E+00 3. 48E-01 2. 42E-02 O.OOE+OO 3.50E-02 4.07E-01 

3.00E+00 3. 22E-01 7. 13E-03 O.OOE+OO 1.39E-02 3. 43E-01 

4.00E+00 2. 92E-01 2.05E-03 O.OOE+OO 5.26E-03 2.99E-01 

5.00E+OO 2. 65E-01 5.80E-04 O.OOE+OO 1. 96E-03 2.67E-01 

6.00E+00 2.41E-01 1.62E-04 O.OOE+OO 7.25E-04 2. 42E-01 

7.00E+OO 2.21E-01 4. 47E-05 O.OOE+OO 2.67E-04 2. 21E-01 

8.00E+00 2.04E-01 1. 22E-05 O.OOE+OO 9. 85E-05 2.04E-01 

9.00E+00 1.90E-01 3. 32E-06 O.OOE+OO 3. 62E-05 1.90E-01 

1.00E+01 1.78E-01 8. 96E-07 O.OOE+OO 1.33E-05 1.78E-01 

2.00E+01 1.20E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-01 

3.00E+01 1.06E-01 O.OOE+OO O.OOE+oo O.OOE+oo 1.06E-01 

4.00E+01 1.02E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-0 

5.00E+01 9. 91E-02 O.OOE+OO O.OOE+OO O.OOE+oo 9.91 

6.00E+01 9.70E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.70E-02 

7.00E+01 9.50E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.50E-02 

8.00E+01 9. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.32E-02 

9.00E+01 9. 15E-02 O.OOE+oo O.OOE+OO O.OOE+oo 9. 15E-02 

1.00E+02 8. 99E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 99E-02 

2.00E+02 7. 81E-02 O.OOE+OO O.OOE+OO O.OOE+oo 7.81E-02 

3.00E+02 7.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.04E-02 

4.00E+02 6.4-9E-02 O.OOE+OO O.OOE+oo O.OOE+oo 6. 49E-02 

5.00E+02 6.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.07E-02 

6.00E+02 5. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.73E-02 

7.00E+02 5. 45E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 45E-02 

8.00E+02 5. 22E-02 O.OOE+OO O.OOE+OO O.OOE+oo 5. 22E-02 

9.00E+02 5.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.02E-02 

1.00E+03 4. 84E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.84E-02 

2.00E+03 3. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 64E-02 

4.00E+03 2. 28E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 28E-02 

8.00E+03 1.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.05E-02 

1.00E+04 7. 51E-03 O.OOE+oo O.OOE+OO O.OOE+OO 7. 51E-03 

2.00E+04 1.60E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-03 

B-76 
CLASS D AHAD ... 1 HICRON BAI..FLIFB== 1.06:£+04 DAYS STRORTIUH 90 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-0l 2.7SE-02 4.90E-03 

2.00E-Ol 3.8lE-02 7.4lE-03 

3.00E-Ol 4. SSE-02 1.04E-02 

4.00E-Ol S.21E-02 1.42E-02 

S.OOE-Ol S.82E-02 1.89E-02 

6.00E-Ol 6.40E-02 2. 43E-02 

7.00E-Ol 6.96E-02 3.00E"-02 

8. OOE-O 1 7.SlE-02 3.6lE-02 

9.00E-0l 8.0SE-02 4. 23E-02 

1.OOE+OO 8.S7E-02 8.S7E-02 4.8SE-02 4.8SE-02 

2.00E+OO 4. 63E-02 1. 32E-Ol S.l1E-02 9.96E-02 

3.00E+OO 3. 69E-02 1. 69E-Ol 2. 76E-02 1.27E-Ol 

4.00E+OO 2. 98E-02 1. 99E-OI 1. 39E-02 1.4lE-Ol 

S.OOE+OO 2.4SE-02 2. 23E-Ol 7. 62E-03 1. 49E-ol 

6.00E+OO 2.03E-02 2. 44E-Ol 4.83E-03 1.S3E-0l 

7.00E+OO 1.71E-02 2.6lE-Ol 3. 47E-03 1.S7E-Ol 

8.00E+OO 1. 44E-02 2.7SE-0l 2.71E-03 1.60E-0l 

9.00E+OO 1.22E-02 2. 87E-ol 2. 22E-03 1. 62E-Ol 

1.OOE+Ol 1.04E-02 2.97E-0l 1.8SE-03 1. 64E-Ol 

2.00E+Ol 2. 26E-03 3. 46E-Ol 3. 99E-04 1. 72E-Ol 

3.00E+Ol 6.2lE-04 3. S7E-0l 1.lOE-04 1.74E-Ol 

4.00E+Ol 2.7SE-04 3.6lE-Ol 4.8SE-OS 1.7SE-Ol 

S.OOE+Ol 1. 94E-04 3. 63E-Ol 3. 42E-OS 1.7SE-0l 

6.00E+Ol 1. 68E-04 3. 64E-Ol 2. 96E-OS 1.7SE-Ol 

7.00E+Ol 1.S4E-04 3.66E-Ol 2. 72E-OS 1.7SE-0l 

8.00E+Ol 1. 43E-04 3. 67E-Ol 2.S3E-OS 1.7SE-Ol 

9.00E+Ol 1. 34E-04 3. 68E-Ol 2. 37E-OS 1.76E-0l 

1.OOE+02 1. 26E-04 3. 69E-Ol 2. 22E-OS 1.76E-Ol 

2.00E+02 7. 42E-OS 3.76E-Ol 1.3lE-OS 1.76E-Ol 

3.00E+02 S.04E-OS 3.80E-0l 8. 89E-06 1.76E-Ol 

4.00E+02 3.7lE-OS 3. 82E-Ol 6. S4E-06 1.76E-Ol 

S.OOE+02 2.86E-OS 3. 83E-Ol S.04E-06 1.7SE-Ol 

6.00E+02 2. 27E-OS 3.83E-0l 4.0lE-06 1.7SE-Ol 

7.00E+02 1. 86E-OS 3. 82E-Ol 3. 28E-06 1. 74E-Ol 

8.00E+02 1. SSE-oS 3.8lE-0l 2. 74E-06 1.73E-Ol 

9.00E+02 1. 33E-OS 3.80E-ol 2.3SE-06 1. 72E-Ol 

1.OOE+03 l.l6E-OS 3.79E-0l 2.0SE-06 1.71E-0l 

2.00E+03 S.8SE-06 3. 63E-0l 1.03E-06 1. 62E-Ol 

4.00E+03 2. 94E-06 3. 26E-Ol S.18E-07 1.43E-0l 

8.00E+03 9.8lE-07 2.S7E-Ol 1. 73E-07 1.11E-Ol 

1.OOE+04 6. 33E-07 2.27E-0l 1.12E-07 9. 79E-02 

2.00E+04 1.16E-07 1.20E-Ol 2.04E-08 S.13E-02 

B-77 
CLASS D AHA» = 1 KICRON STABLE znCONIUH 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2. 56E-Ol 2. 26E-Ol 3.0JE-04 1.56E-Ol 6. 38E-Ol 

2.00E-Ol 2. 79E-Ol 2.0lE-Ol 2. 96E-07 1. 56E-Ol 6. 36E-Ol 

3.00E-Ol 2.99E-Ol 1.79E-Ol O.OOE+OO 1.5SE-0l 6.33E-Ol 

4.00E-Ol 3. 1 6E-O 1 1.60E-Ol O.OOE+OO 1. 52E-Ol 6. 28E-Ol 

5.00E-Ol 3. 32E-Ol 1. 43E-Ol O.OOE+OO 1. 48E-Ol 6.22E-Ol 

6.00E-Ol 3. 45E-ol 1.27E-Ol O.OOE+OO 1. 42E-Ol 6.l5E-OI 

7.00E-Ol 3. 58E-Ol 1.l3E-0l O.OOE+OO 1.36E-OI 6.06E-Ol 

8.00E-Ol 3. 68E-Ol 1.OlE-Ol O.OOE+OO 1. 29E-Ol S.98E-Ol 

9.00E-Ol 3.17E-Ol 8.96E-02 O.OOE+OO 1.22E-Ol S.89E-Ol 

1.OOE+OO 3. 85E-Ol 7. 97E-02 O.OOE+OO 1.lSE-Ol S .. 80E-Ol 

2.00E+OO 4. 22E-Ol 2. 42E-02 O.OOE+OO S.24E-02 4.98E-Ol 

3.00E+OO 4.20E-Ol 7.l3E-03 O.OOE+OO 2.09E-02 4. 48E-Ol 

4.00E+OO 4.08E-Ol 2.0SE-03 O.OOE+OO 7. 94E-03 4.l8E-0l 

5.00E+OO 3. 93E-Ol S.8lE-04 O.OO~;+OO 2. 96E-03 3. 97E-Ol 

6.00E+OO 3. 79E-Ol 1. 62E-04 O.OOE+OO I.1OE-03 3.80E-Ol 

7.00E+OO 3. 66E-Ol 4. 47E-OS O.OOE+OO 4.04E-04 3. 67E-Ol 

8.00E+OO 3. 54E-Ol 1. 22E-OS O.OOE+OO 1. 49E-04 3. 54E-Ol 

9.00E+OO 3. 43E-Ol 3. 32E-06 O.OOE+OO 5. 48E-05 3. 44E-Ol 

1.OOE+Ol 3. 34E-Ol 8. 96E-07 O.OOE+OO 2.02E-05 3.34E-Ol 

2.00E+Ol 2. 75E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 75E-Ol 

3.00E+Ol 2. 53E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.S3E-Ol 

4.00E+Ol 2.44E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.44E-Ol 

5.00E+Ol 2.4lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.4lE-Ol 

6.00E+Ol 2.40E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.40E-Ol 

7.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 39E-Ol 

8.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 39E-Ol 

9.00E+Ol 2. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 38E-0l 

1.OOE+02 2. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 38E-Ol 

2.00E+02 2. 36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 36E-Ol 

3.00E+02 2. 34E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.34E-Ol 

4.00E+02 2. 32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.32E-Ol 

5.00E+02 2.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.30E-Ol 

6.00E+02 2. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 28E-Ol 

7.00E+02 2. 26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.26E-Ol 

8.00E+02 2. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 24E-Ol 

9.00E+02 2. 22E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 22E-Ol 

1.OOE+03 2.20E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2.20E-Ol 

2.00E+03 2.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.02E-Ol 

4.00E+03 1.70E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.70E-Ol 

8.00E+03 1.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-Ol 

1.OOE+04 1.OlE-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.OlE-Ol 

2.00E+04 4. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 25E-02 

B-78 
CLASS D AHAD - 1 MICRON S'lABLB ZlB.CORIUK 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.04E-03 6.07E-05 

2.00E-ol 2.36E-03 7. 42E-04 

3.00E-Ol 3.77E-03 2. 64E-03 

4.00E-Ol 5. 28E-03 5. 93E-03 

5.00E-Ol 6. 85E-03 1.05E-02 

6.00E-Ol 8.49E-03 1.61E-02 

7.00E-Ol 1.02E-02 2. 25E-02 

8.00E-Ol 1. 19E-02 2. 94E-02 

9.00E-ol 1. 37E-02 3. 66E-02 

1.00E+OO 1. 55E-02 1. 55E-02 4.40E-02 4.40E-02 

2.00E+00 1.90E-02 3. 46E-02 6. 23E-02 1.06E-Ol 

3.00E+00 1. 88E-02 5. 33E-02 3. 15E-02 1. 38E-Ol 

4.00E+00 1.75E-02 7.08E-02 1. 29E-02 1. 51E-Ol 

5.00E+00 1. 59E-02 8. 67E-02 4. 98E-03 1. 56E-Ol 

6.00E+00 1. 45E-02 1.01E-Ol 1.87E-03 1. 58E-Ol 

7.00E+00 1. 31E-02 1.14E-Ol 6. 92E-04 1. 58E-Ol 

8.00E+00 1. 19E-02 1.26E-Ol 2. 55E-04 1. 59E-Ol 

9.00E+00 1.08E-02 1.37E-Ol 9.40E-05 1. 59E-Ol 

1.00E+Ol 9.77E-03 1.47E-Ol 3.46E-05 1.59E-Ol 

2.00E+Ol 3. 64E-03 2.06E-Ol O.OOE+OO 1. 59E-Ol 

3.00E+Ol 1. 37E-03 2. 28E-Ol O.OOE+oo 1.59E-Ol 

4.00E+Ol 5. 21E-04 2. 36E-Ol O.OOE+OO 1. 59E-Ol 

5.00E+Ol 2.07E-04 2. 39E-Ol O.OOE+oo 1. 59E-Ol 

6.00E+Ol -8. 97E-05 2.41E-Ol O.OOE+OO 1. 59E-Ol 

7.00E+Ol 4. 63E-05 2.41E-Ol O.OOE+OO 1. 59E-Ol 

8.00E+Ol 3.02E-05 2. 42E-Ol O.OOE+OO 1. 59E-Ol 

9.00E+Ol 2. 42E-05 2. 42E-Ol O.OOE+oo 1.59E-Ol 

1.00E+02 2. 19E-05 2. 42E-Ol O.OOE+OO 1. 59E-Ol 

2.00E+02 2.05E-05 2. 44E-Ol O.OOE+oo 1. 59E-Ol 

3.00E+02 2.03E-05 2. 46E-Ol O.OOE+OO 1. 59E-Ol 

4.00E+02 2.01E-05 2. 48E-Ol O.OOE+OO 1.59E-Ol 

5.00E+02 1. 99E-05 2.50E-Ol O.OOE+OO 1. 59E-Ol 

6.00E+02 1. 98E-05 2. 52E-Ol O.OOE+OO 1. 59E-Ol 

7.00E+02 1. 96E-05 2. 54E-Ol O.OOE+OO 1. 59E-Ol 

8.00E+02 1.94E-05 2.56E-Ol O.OOE+OO 1.59E-Ol 

9.00E+02 1.93£-05 2. 58E-Ol O.OOE+OO 1. 59E-Ol 

1.00E+03 1.91E-05 2.60E-Ol O.OOE+OO 1. 59E-Ol 

2.ooE+03 1. 75E-05 2. 78E-Ol O.OOE+OO 1.59E-Ol 

4.00E+03 1.47E-05 3. 11E-Ol O.OOE+oo 1. 59E-Ol 

8.00E+03 1.04E-05 3.60E-Ol O.OOE+OO 1. 59E-Ol 

1.00E+04 8. 75E-06 3. 79E-Ol O.OOE+OO 1. 59E-Ol 

2.00E+04 3. 68E-06 4. 38E-Ol O.OOE+OO 1. 59E-Ol 

B-79 
CLASS D AHA» = 1 MICRON STABLE MOLYBDENUM 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 3.37E-Ol 2. 26E-OI 3.03E-04 7.41E-02 6. 37E-Ol 

2.00E-Ol 3.95E-Ol 2.01E-Ol 2. 96E-07 3. 72E-02 6. 34E-Ol 

3.00E-Ol 4.19E-Ol 1.79E-Ol O.OOE+OO 3.14E-02 6.30E-Ol 

4.00E-OI 4.36E-Ol 1.60E-OI O.OOE+OO 2. 98E-02 6. 26E-Ol 

5.00E-Ol 4.51E-Ol 1.43E-Ol O.OOE+OO 2. 85E-02 6. 22E-Ol 

6.00E-Ol 4. 63E-Ol 1.27E-OI O.OOE+OO 2.71E-02 . 6.I7E-OI 

7.00E-Ol 4. 74E-Ol 1. 13E-Ol O.OOE+OO 2. 56E-02 6. 13E-Ol 

8.00E-OI 4. 84E-OI 1.OIE-OI O.OOE+OO 2.41E-02 6.09E-OI 

9.00E-Ol 4.92E-OI 8. 96E-02 O.OOE+OO 2. 25E-02 6.04E-Ol 

I.OOE+OO 4. 99E-Ol 7. 97E-02 O.OOE+OO 2.10E-02 6.00E-Ol 

2.00E+OO 5.3IE-OI 2. 42E-02 O.OOE+OO 9. 24E-03 5. 65E-OI 

3.00E+OO 5.31E-Ol 7.13E-03 O.OOE+OO 3. 64E-Q3 5. 42E-Ol 

4.00E+OO 5.24E-OI 2.05E-03 O.OOE+OO 1.38E-03 5. 27E-Ol 

5.00E+OO 5.I5E-Ol 5.81E-04 O.OOE+OO 5.12E-04 5.16E-OI 

6.00E+OO . 5.07E-OI 1.62E-04 O.OOE+OO I. 89E-04 5.07E-OI 

7.00E+OO 4. 99E-Ol 4.47E-05 O.OOE+OO 6. 98E-05 5.00E-Ol 

8.00E+OO 4.92E-Ol I. 22E-OS O.OOE+OO 2.S7E-OS 4. 92E-Ol 

9.00E+OO 4.8SE-Ol 3. 32E-O.6 O.OOE+OO 9.47E-06 4.8SE-OI 

1.OOE+OI 4. 78E-Ol 8. 96E-07 O.OOE+OO 3. 48E-06 4.78E-0l 

2.00E+Ol 4.16E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.16E-OI 

3.00E+Ol 3.63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 63E-Ol 

4.00E+Ol 3.16E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.16E-OI 

S.OOE+OI 2.7SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.7SE-Ol 

6.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 39E-OI 

7.00E+Ol 2.08E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.08E-Ol 

8.00E+Ol 1.8IE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.8IE-OI 

9.00E+Ol 1.S8E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.S8E-Ol 

1.OOE+02 1.37E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.37E-Ol 

2.00E+02 3. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 44E-02 

3.00E+02 8.S9E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.S9E-03 

4.00E+02 2.ISE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.1SE-03 

S.OOE+02 S.37E-04 O.OOE+OO O.OOE+OO O.OOE+OO S.37E-04 

6.00E+02 1. 34E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 34E-04 

7.00E+02 3. 36E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3. 36E-OS 

8.00E+02 8.40E-06 O.OOE+OO O.OOE+OO O.OOE+OO 8.40E-06 

9.00E+02 2.10E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.lOE-06 

1.OOE+03 S.2SE-07 O.OOE+OO O.OOE+OO O.OOE+OO S.2SE-07 

B-80 
CLASS D AHAD - 1 MICRON STABLE MOLYBDENUM. 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1. 96E-03 4.l6E-05 

2.00E-Ol 4. 83E-03 3. BOE-04 

3.00E-Ol 7.85E-03 1.lOE-03 

4.00E-Ol 1.09E-02 2.l2E-03 

5.00E-Ol 1. 39E-02 3. 37E-03 

6.00E-Ol 1. 69E-02 4. 75E-03 

7.00E-Ol 1.9BE-02 6. 23E-03 

B.OOE-Ol 2. 27E-02 7. 75E-03 

9.00E-Ol 2. 55E-02 9. 27E-03 

1.OOE+OO 2.B3E-02 2. 83E-02 1.OBE-02 1.OBE-02 

2.00E+OO 2. 37E-02 5.l9E-02 1.lBE-02 2.26E-02 

3.00E+OO 1.71E-02 6.90E-02 5.60E-03 2.B2E-02 

4.00E+OO 1. 26E-02 B.l7E-02 2. 26E-03 3.04E-02 

5.00E+OO 9. 99E-03 9.17E-02 B.64E-04 3.l3E-02 

6.00E+OO B.52E-03 1.OOE-Ol 3.23E-Q4 3.l6E-02 

7.00E+OO 7.70E-03 1.OBE-Ol 1.20E-04 3.l7E-02 

8.00E+OO 7. 24E-03 1.I5E-Ol 4.4IE-05 3.lBE-02 

9.00E+OO 6. 96E-03 I.22E-OI 1. 63E-05 3.l8E-02 

I.OOE+OI 6.77E-03 1. 29E-Ol 5.9BE-06 3.l8E-02 

2.00E+Ol 5.BlE-03 I.9lE-Ol O.OOE+OO 3.IBE-02 

3.00E+OI 5.06E-03 2. 45E-OI O.OOE+OO 3.lBE-02 

4.00E+Ol 4.4lE-03 2. 92E-Ol O.OOE+OO 3.18E-02 

5.00E+Ol 3.B4E-03 3. 33E-Ol O.OOE+OO 3.18E-02 

6.00E+Ol 3. 34E-03 3. 68E-Ol O.OOE+OO 3.IBE-02 

7.00E+Ol 2.9IE-03 3. 99E-Ol O.OOE+OO 3.lBE-02 

8.00E+OI 2. 53E-03 4. 26E-Ol O.OOE+OO 3.l8E-02 

9.00E+Ol 2.20E-03 4.49E-Ol O.OOE+OO 3.IBE-02 

l.OOE+02 I.92E-03 4.70E-Ol O.OOE+OO 3.lBE-02 

2.00E+02 4.80E-04 5. 73E-Ol O.OOE+OO 3.lBE-02 

3.00E+02 1.20E-04 5. 99E-Ol O.OOE+OO 3.IBE-02 

4.00E+02 3.00E-05 6.05E-OI O.OOE+OO 3.l8E-02 

5.00E+02 7.50E-06 6.07E-Ol O.OOE+OO 3.l8E-02 

6.00E+02 1.BBE-06 6.07E-OI O.OOE+OO 3.lBE-02 

7.00E+02 4. 69E-07 6.07E-Ol O.OOE+OO 3.lBE-02 " " . 8.00E+02 1.l7E-07 6.07E-Ol O.OOE+OO 3.IBE-02 

9.00E+02 2. 93E-OB 6.07E-Ol O.OOE+OO 3.lBE-02 

B-BI 
CLASS D AMAD - 1 HICItON HALFLIFK= 1.538+09 DAYS TBCllRETIUK 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 29E-Ol 2. 26E-Ol 3.03E-04 7.4lE-02 6. 29E-Ol 

2.00E-Ol 3. 76E-Ol 2.0lE-Ol 2. 96E-07 3. 72E-02 6.lSE-Ol 

3.00E-Ol 3. 88E-Ol 1.79E-Ol O.OOE+OO 3.l4E-02 S.99E-Ol 

4.00E-Ol 3. 93E-Ol 1.60E-Ol O.OOE+OO 2. 98E-02 S.83E-Ol 

S.OOE-Ol 3~9SE-Ol 1. 43E-Ol O.OOE+OO 2.8SE-02 S.66E-Ol 

6.00E-Ol 3. 96E-Ol 1. 27E-Ol O.OOE+OO 2.71E-02 S.SOE-Ol 

7.00E-0l 3.94E-0l 1.13E-0l O.OOE+OO 2.S6E-02 S.33E-Ol 

8.00E-Ol 3. 92E-Ol 1.OlE-0l O.OOE+OO 2.4lE-02 S.17E-Ol 

9.00E-Ol 3. 89E-Ol 8. 96E-02 O.OOE+OO 2.2SE-02 S.OlE-Ol 

1.OOE+OO 3. 84E-Ol 7. 97E-02 O.OOE+OO 2.lOE-02 4. 85E-Ol 

2.00E+OO 3.l4E-Ol 2. 42E-02 O.OOE+OO 9. 24E-03 3. 48E-Ol 

3.00E+OO 2. 39E-Ol 7.13E-03 O.OOE+OO 3. 64E-03 2.S0E-Ol 

4.00E+OO 1.80E-Ol ·2.0SE-03 O.OOE+OO 1. 38E-03 1. 84E-Ol 

S.OOE+OO 1. 37E-Ol S.8lE-04 O.OOE+OO S.12E-04 1. 38E-0l 

6.00E+OO 1.06E-Ol 1. 62E-04 O.OOE+OO 1.89E-04 1. o 6E..,..O 1 

7.00E+OO 8.4lE-02 4. 47E-OS O.OOE+OO 6. 98E-OS 8. 42E-02 

8.00E+OO 6. 83E-02 1. 22E-OS O.OOE+OO 2.S7E-OS 6.83E-02 

9.00E+OO S.68E-02 3. 32E-06 O.OOE+OO 9. 47E-06 S.68E-02 

1.OOE+Ol 4. 82E-02 8. 96E-07 O.OOE+OO 3. 48E-06 4. 82E-02 

2.00E+Ol 1. 88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.88E-02 

3.00E+Ol 1.19E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.19E-02 

4.00E+Ol 8. 44E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.44E-03 

5.00E+Ol 6.l2E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.l2E-03 

6.00E+Ol 4.46E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 46E-03 

7.00E+Ol 3.2SE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.2SE-03 

8.00E+Ol 2. 37E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 37E-03 

9.00E+0l 1.73E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.73E-03 

1.OOE+02 1. 26E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 26E-03 

2.00E+02 5. 42E-OS O.OOE+OO O.OOE+OO O.OOE+OO 5. 42E-05 

3.00E+02 2. 27E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 27E-06 

4.00E+02 2.67E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2. 67E-08 

B-82 
ClASS D AHA» - 1 HICKOK BALFLlFE= 1.53£+09 DAYS 'I'ECllRETIUK 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 9.12E-03 4.16E-05 

2.00E-OI 2.40E-02 3. BOE-04 

3.00E-OI 3.9IE-02 I.IOE-03 

4.00E-Ol 5. 44E-02 2.12E-03 

5.00E-Ol 6. 96E-02 3. 37E-03 

6.00E-OI 8.4BE-02 4. 75E-03 

7.00E-OI 9.9BE-02 6. 23E-03 

B.OOE-OI 1.15E-OI 7. 75E-03 

9.00E-OI 1. 29E-Ol 9. 27E-03 

I.OOE+OO 1.44E-OI 1.44E-OI l.OBE-02 I.OBE-02 

2.00E+OO 1. 25E-OI 2. 69E-OI I.IBE-02 2.26E-02 

3.00E+OO 9.IBE-02 3.6IE-OI 5.60E-03 2.B2E-02 

4.00E+OO 6. 44E-02 4. 25E-OI 2. 26E-03 3.04E-02 

5.00E+OO 4. 47E-02 4.70E-OI B.64E-04 3.13E-02 

6.00E+OO 3.12E-02 5.0IE-OI 3.23E-04 3.16E-02 

7.00E+OO 2.2IE-02 5. 23E-OI 1.20E-04 3.l7E-02 

B.OOE+OO 1.5BE-02 5. 39E-OI 4.4IE-05 3.IBE-02 

9.00E+OO 1.16E-02 5.5IE-OI I. 63E-05 3.IBE-02 

I.OOE+OI B.60E-03 5. 59E-OI 5.9BE-06 3.IBE-02 

2.00E+OI I. 11E-03 5.B9E-OI O.OOE+OO 3.IBE-02 

3.00E+OI 4. 62E-04 5. 95E-OI O.OOE+OO 3.IBE-02 

4.00E+OI 2. 82E-04 5. 99E-OI O.OOE+OO 3.IBE-02 

5.00E+OI 1.9BE-04 6.0lE-OI O.OOE+OO 3.IBE-02 

6.00E+OI 1'. 43E-04 6.03E-Ol O.OOE+OO 3.IBE-02 

7.00E+OI I.04E-04 6.04E-OI O.OOE+OO 3.IBE-02 

8.00E+OI 7.60E-05 6.05E-OI O.OOE+OO 3.IBE-02 

9.00E+OI 5. 54E-05 6.06E-OI O.OOE+OO 3.1BE-02 

I.OOE+02 4.05E-05 6.06E-Ol O.OOE+OO 3.18E-02 

2.00E+02 1.7IE-06 6.07E-OI O.OOE+OO 3.IBE-02 

3.00E+02 3. 37E-OB 6.07E-OI O.OOE+OO 3.IBE-02 

B-83 
CI.ASS D AHAD = 1 KIeRON STABLE KlJTB.EBIDK 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 52E-Ol 2. 26E-Ol 3.03E-04 1. 54E-Ol 6. 32E-Ol 

2.00E-Ol 2.70E-Ol 2.0IE-Ol 2. 96E-07 1. 52E-Ol 6.23E-Ol 

3.00E-Ol 2.85E-0l 1.79E-Ol O.OOE+OO 1.49E-0l 6.l4E-Ol 

4.00E-Ol 2.98E-Ol 1.60E-Ol O.OOE+OO 1. 45E-Ol 6.04E-Ol 

5.00E-Ol 3.l0E-0l 1.43E-Ol O.OOE+OO 1.4lE-0l 5. 93E-Ol 

6.00E-Ol 3.l9E-Ol 1. 27E-Ol O.OOE+OO 1. 35E-Ol 5. 82E-Ol 

7.00E-Ol 3.28E-Ol 1.13E-Ol O.OOE+OO 1.29E-Ol 5.70E-Ol 

8.00E-Ol 3.35E-Ol 1.OlE-Ol O.OOE+OO 1. 22E-Ol 5. 58E-Ol 

9.00E-Ol 3. 42E-0l 8.96E-02 O.OOE+OO 1.16E-0l 5. 47E-Ol 

1.OOE+OO 3.47E-Ol . 7. 97E-02 O.OOE+OO 1.09E-Ol 5.36E-Ol 

2.00E+OO 3. 12E-Ol 2. 42E-02 O.OOE+OO 4.95E-02 4. 45E-Ol 

3.00E+OO 3.69E-Ol 7.l3E-03 O.OOE+OO 1. 97E-02 3. 96E-Ol 

4.00E+OO 3. 58E-Ol 2.05E-03 O.OOE+OO 7.49E-03 3. 68E-Ol 

5.00E+OO 3. 46E-Ol 5.8lE-04 O.OOE+OO 2. 79E-03 3.50E-Ol 

6.00E+OO 3.34E-Ol 1.62E-04 O.OOE+OO 1.03E-03 3. 35E-Ol 

7.00E+OO 3.23E-Ol 4. 47E-05 O.OOE+OO 3.8lE-04 3. 23E-Ol 

8.00E+OO 3.l2E-0l 1. 22E-05 O.OOE+OO 1.40E-04 3.l2E-Ol 

9.00E+OO 3.02E-Ol 3. 32E-06 O.OOE+OO 5.16E-05 3.02E-Ol 

1.OOE+Ol 2.93E-Ol 8. 96E-07 O.OOE+OO 1.90E-05 2. 93E-Ol 

2.00E+Ol 2.27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 27E-Ol 

3.00E+Ol 1.90E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.90E-Ol 

4.00E+Ol 1.67E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.67E-Ol 

5.00E+Ol 1.52E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 52E-Ol 

6.00E+Ol 1.40E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-Ol 

7.00E+Ol 1.30E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-0l 

8.00E+Ol 1.23E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.23E-Ol 

9.00E+Ol 1.17E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.17E-0l 

1.OOE+02 1.12E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-Ol 

2.00E+02 8. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 78E-02 

3.00E+02 7.97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.97E-02 

4.00E+02 7.o'4lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.4lE-02 

5.00E+02 6.9lE-02 O.OOE+OO O.OOE*OO O.OOE+OO 6.9lE-02 

6.00E+02 6. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 44E-02 

7.00E+02 6.0lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.0lE-02 

8.00E+02 5.6lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.6lE-02 

9.00E+02 5. 23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 23E-02 

1.00E+03 4. 88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 88E-02 

2.00E+03 2. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 44E-02 

4.00E+03 6.l1E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.l1E-03 

8.00E+03 3. 82E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3. 82E-04 

1.00E+04 9. 55E-05 O.OOE+OO O.OOE+OO O.OOE+OO 9. 55E-05 

2.00E+04 8.09E-08 O.OOE+OO O.OOE+OO O.OOE+OO 8.09E-08 

B-84 
ClASS D AMAD ... 1 MICRON STABLE RUTIIKHIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 7.42E-03 6.04E-05 

I 2.00E-01 1.55E-02 7.33E-04 

3.00E-01 2. 29E-02 2.60E-03 

4.00E-01 2. 98E-02 5. 81E:-03 

5.00E-01 3.61E-02 1.02E-02 

6.00E-01 4. 19E-02 1. 56E-02 

7.00E-01 4.73E-02 2. 18E-02 

8.00E-01 5. 22E-02 2. 84E-02 

9.00E-01 5. 68E-02 3. 54E-02 

1.00E+OO 6.llE-02 6.llE-02 4. 24E-02 4. 24E-02 

2.00E+OO 3.10E-02 9. 22E-02 5.92E-02 1.02E-01 

3.00E+OO 1. 99E-02 1. 12E-01 2. 98E-02 1.31E-01 

4.00E+OO 1. 56E-02 1. 28E-01 1. 22E-02 1.44E-01 

5.00E+OO 1.36E-02 1.41E-01 4.70E-03 1.48E-01 

6.00E+OO 1. 24E-02 1. 54E-01 1. 76E-03 1.50E-01 

7.00E+OO 1. 15E-02 1.65E-Ol 6. 52E-04 1. 51E-01 

8.00E+OO 1.07E-02 1.76E-01 2. 41E-04 1.51E-01 

9.00E+OO 9. 93E-03 1. 86E-01 8. 87E-05 1.51E-01 

1.00E+01 9.27E-03 1.95E-01 3.26E-05 1.51E-01 

2.00E+01 4.90E-03 2.61E-01 O.OOE+OO 1.51E-01 

3.00E+01 2.90E-03 2. 98E-01 O.OOE+OO 1.51E-01 

4.00E+01 1.91E-03 3.21E-01 O.OOE+OO 1.51E-Ol 

5.00E+01 1. 38E-03 3.37E-01 O.OOE+OO 1.51E-01 

6.00E+01 1.05E-03 3.48E-01 O.OOE+OO 1.51E-01 

7.00E+0l 8.41E-04 3.58E-01 O.OOE+OO 1.51E-01 

8.00E+01 6. 86E-04 3. 65E-01 O.OOE+OO 1. 51E-01 

9.00E+01 5. 68E-04 3.71E-01 O.OOE+OO 1.51E-01 

1.00E+02 4. 74E-04 3.77E-01 O.OOE+OO 1.51E-Ol 

2.00E+02 1. 15E-04 4.00E-01 O.OOE+OO 1.51E-01 

3.00E+02 6. 28E-05 4.08E-01 O.OOE+OO 1.51E-01 

4.00E+02 5. 24E-05 4. 14E-01 O.OOE+OO 1.51E-01 

5.00E+02 4.80E-05 4. 19E-01 O.OOE+OO 1.51E-01 

6.00E+02 4.47E-05 4.24E-01 O.OOE+OO 1.51E-01 

7.00E+02 4.17E-05 4. 28E-01 O.OOE+OO 1.51E-01 .,.' . 

.' . 8.00E+02 3.89E-05 4.32E-01 O.OOE+OO 1.51E-01 

9.00E+02 3. 63E-05 4. 36E-01 O.OOE+OO 1.51E-01 

1.00E+03 3. 39E-05 4.39E-01 O.OOE+OO 1.51E-01 

2.00E+03 1.69E-05 4. 64E-01 O.OOE+OO 1.51E-01 

4.00E+03 4. 23E-06 4.82E-01 O.OOE+OO 1.51E-0l 

8.00E+03 2. 67E-07 4.88E-01 O.OOE+OO 1.51E-01 

1.00E+04 6. 87E-08 4.88E-01 O.OOE+OO 1.51E-01 

B-85 
CLASS D AHAD == 1 MICR.ON STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE 

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 2.41E-Ol 2. 26E-01 3.03E-04 1.56E-01 6. 23E-Ol 

2.00E-01 2. 48E-Ol 2.01E-oi 2. 96E-07 1. 56E-Ol 6.05E-Ol 

3.00E-Ol 2. 55E-Ol 1.79E-Ol O.OOE+OO 1.54E-Ol 5. 89E-0l 

4.00E-01 2. 61E-Ol 1.60E-Ol O.OOE+OO 1. 51E-01 5. 73E-Ol 

5.00E-Ol 2. 67E-01 1.43E-Ol O.OOE+OO 1.47E-0l 5. 57E-Ol 

6.00E-Ol 2. 73E-01 1. 27E-Ol O.OOE+OO 1. 42E-Ol 5!41E-01 

7.00E-Ol 2. 77E-Ol 1.13E-Ol O.OOE+OO 1. 35E-01 5.26E-Ol 

8.00E-Ol 2. 82E-Ol 1.0IE-Ol O.OOE+OO 1. 29E-Ol 5.11E-Ol 

9.OOE-0l 2.85E-01 8. 96E-02 O.OOE+OO 1.2lE-OI 4. 97E-01 

1.00E+OO 2. 89E-01 7. 97E-02 O.OOE+OO 1. 14E-Ol 4. 83E-Ol 

2.00E+OO 3.02E-01 2.42E-02 O.OOE+OO 5. 22E-02 3. 78E-01 

3.00E+OO 2. 96E-01 7.13E-03 O.OOE+OO 2.08E-02 3. 24E-01 

4.00E+OO 2. 85E-0l 2.05E-03 O.OOE+OO 7.9lE-03 2. 95E-Ol 

5.00E+OO 2.73E-Ol 5.81E-04 O.OO~:rOO 2. 95E-03 2. 76E-Ol 

6.00E+OO 2.61E-Ol 1.62E-04 O.OOE+OO 1.09E-03 2. 62E-Ol 

7.00E+OO 2. 49E-Ol 4.47E-05 O.OOE+OO 4.03E-04 2. 49E-01 

8.00E+OO 2.38E-0l lo22E-05 O.OOE+OO 1.48E-04 2. 38E-Ol 

9.OOE+OO 2.27E-Ol 3. 32E-06 O.OOE+OO 5. 46E-05 2. 27E-01 

1.00E+Ol 2.17E-01 8. 96E-07 O.OOE+OO 2.01E-05 2.l7E-0l 

2.00E+Ol l.37E-Ol O.OOE+OO O.OOE+OO O.OOE+OO l.37E-Ol 

3.00E+01 8.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 

4.00E+Ol 5. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 42E-O 

5.00E+Ol 3. 41E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.41 

6000E+Ol 2. 15E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.l5E-02 

7.00E+01 l.36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.36E-02 

8.00E+01 8. 54E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8. 54E-03 

9.OOE+Ol 5. 38E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5. 38E-OJ 

1.OOE+02 3. 39E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 39E-03 

2.00E+02 3. 34E-05 O.OOE+OO OoOOE+OO O.OOE+OO 3.34E-05 

3.00E+02 3. 29E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3. 29E-07 

B-86 
ClASS D AMAD - 1 HICIlOlf STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1. 63E-02 6.07E-05 

2.00E-0l 3.30E-02 7.41E-04 

3.00E-0l 4. 76E-02 2. 64E-03 

4.00E-01 6.04E-02 5. 92E-03 

5.00E-01 7. 17E-02 1.05E-02 

6.00E-01 8. 17E-02 1.61E-02 

7.00E-01 9.07E-02 2. 24E-02 

8.00E-01 9. 88E-02 2. 93E-02 

9.00E-01 1.06E-01 3.65E-02 

1.00E+OO 1. 13E-01 1.l3E-Ol 4. 39E-02 4. 39E-02 

2.00E+OO 4.25E-02 1.55E-01 6.21E-02 1.06E-01 

3.00E+OO 2. 26E-02 1. 78E-01 3. 14E-02 1. 37E-01 

4.00E+OO 1.61E-02 1. 94E-01 1.29E-02 1.50E-01 

5.00E+OO 1. 37E-02 2.08E-01 4. 96E-03 1. 55E-01 

6.00E+OO 1.25E-02 2.20E-01 1. 86E-03 1.57E-01 

7.00E+OO 1. 18E-02 2. 32E-01 6. 89E-04 1. 58E-01 

8.00E+OO 1. 13E-02 2. 43E-01 2. 54E-04 1. 58E-01 

9.00E+OO 1.07E-02 2. 54E-01 9. 37E-05 1. 58E-01 

1.00E+01 1.02E-02 2. 64E-01 3. 45E-05 1. 58E-01 

2.00E+01 6. 46E-03 3. 44E-01 O.OOE+OO 1. 58E-01 

3.00E+01 4.07E-03 3. 95E-01 O.OOE+OO 1.58E-0l 

4.00E+01 2. 56E-03 4. 27E-01 O.OOE+OO 1. 58E-01 

5.00E+01 1. 61E-03 4. 47E-0l O.OOE+OO 1.58E-01 

6.00E+01 1.02E-03 4. 59E-01 O.OOE+OO 1. 58E-01 

7.00E+01 6. 41E-04 4. 67E-0l O.OOE+OO 1. 58E-01 

8.00E+01 4.04E-04 4. 72E-Ol O.OOE+OO 1. 58E-Ol 

9.00E+01 2. 54E-04 4.76E-01 O.OOE+OO 1.58E-0l 

1.00E+02 1.60E-04 4. 78E-01 O.OOE+OO 1. 58E-Ol 

2.00E+02 1. 58E-06 4.81E-Ol O.OOE+OO 1.58E-01 

3.00E+02 1. 57E-08 4.81E-Ol O.OOE+OO 1. 58E-Ol 

B-87 
CLASS D AHAD - 1 MICRON STABLE SILVER. 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 58E-Ol 2. 26E-Ol 3.03E-04 1. 54E-0l 6. 38E-Ol 

2.00E-Ol 2.84E-Ol 2.0lE-Ol 2. 96E"':07 1. 52E-Ol 6. 37E-01 

3.00E-Ol 3.06E-Ol 1.79E-0l O.OOE+OO 1. 49E-01 6. 34E-Ol 

4.00E-01 3.25E-01 1.60E-Ol O.OOE+OO 1.45E-01 6.30E-Ol 

5.00E-01 3.4lE-Ol 1.43E-01 O.OOE+OO 1.41E-0l 6.24E-01 

6.00E-Ol 3. 56E-Ol 1.27E-Ol O.OOE+OO 1. 35E-Ol 6.l8E-Ol 

7.00E-Ol 3. 68E-Ol 1.13E-01 O.OOE+OO 1. 29E-Ol 6. 11E-01 

8.00E-01 3.80E-OI 1.OIE-OI O.OOE+OO 1. 22E-OI 6.03E-OI 

9.00E-OI 3.90E-OI 8.96E-02 O.OOE+OO 1. 16E-01 5. 95E-OI 

I.OOE+OO 3. 98E-01 7. 97E-02 O.OOE+OO 1.09E-01 5. 87E-Ol 

2.00E+OO 4.4lE-Ol 2. 42E-02 O.OOE+OO 4. 95E-02 5.l5E-Ol 

3.00E+OO 4.47E-OI 7.l3E-03 O.OOE+OO 1. 97E-02 4. 73E-Ol 

4.00E+OO 4.4lE-OI 2.05E-03 O.OOE+OO 7.49E-03 4.50E-01 

5.00E+OO 4.32E-01 5.8IE-04 O.OOE+OO 2. 79E-03 4.35E-Ol 

6.00E+OO 4.23E-Ol 1.62E-04 O.OOE+OO I.03E-03 4. 24E-Ol 

7.00E+OO 4.ISE-Ol 4. 47E-05 O.OOE+OO 3. 81E-04 4.1SE-Ol 

8.00E+OO 4.07E-OI 1. 22E-OS O.OOE+OO 1.40E-04 4.07E-OI 

9.00E+OO 3. 99E-OI 3.32E-06 O.OOE+OO 5.l6E-OS 3. 99E-Ol 

1.OOE+Ol 3. 92E-OI 8. 96E-07 O.OOE+OO 1.90E-OS 3. 92E-Ol 

2.00E+Ol 3. 36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 36E-OI 

3.00E+Ol 2.92E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 92E-OI 

4.00E+Ol 2.S4E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.S4E-O 

S.OOE+Ol 2.2lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.2lE-Ol 

6.00E+Ol 1. 92E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 92E-01 

7.00E+Ol 1. 68E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 68E-Ol 

8.00E+01 1.46E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.46E-Ol 

9.00E+01 1. 27E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 27E-Ol 

1.OOE+02 1.llE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.llE-Ol 

2.00E+02 2. 76E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 76E-02 

3.00E+02 6.9IE-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.9lE-03 

4.00E+02 1. 73E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 73E-03 

S.OOE+02 4. 32E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 32E-04 

6.00E+02 1.08E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.08E":04 

7.00E+02 2.70E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.70E-OS 

8.00E+02 6.76E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6. 76E-06 

9.00E+02 1. 69E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 69E-06 

1.00E+03 4.22E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4.22E-07 

B-88 
CLASS D .AHAD = 1 MICRON STABLE SILVER. 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6.80E-04 6.04E-05 

2.00E-Ol 1. 55E-03 7. 33E-04 

3.00E-Ol 2. 48E-03 2.60E-03 

4.00E-Ol 3. 47E-03 5.81E-03 

5.00E-Ol 4.51E-03 1.02E-02 

6.00E-Ol 5. 59E-03 1.56E-02 

7.00E-Ol .6.70E-03 2.18E-02 

8.00E-Ol 7. 84E-03 2. 84E-02 

9.00E-Ol 9.00E-03 3. 54E-02 

1.OOE+OO 1.02E-02 1.02E-02 4. 24E-02 4. 24E-02 

2.00E+OO 1. 23E-02 2. 25E-02 5. 92E-02 1.02E-Ol 

3.00E+OO 1.19E-02 3. 44E-02 2. 98E-02 1.31E-Ol 

4.00E+OO 1.lOE-02 4. 54E-02 1.22E-02 1.44E-Ol 

5.00E+OO 1.OlE-02 5. 56E-02 4.70E-03 1. 48E-0l 

6.00E+OO 9. 27E-03 6.48E-02 1. 76E-03 1.50E-Ol 

7.00E+OO 8. 55E-03 7. 34E-02 6. 52E-04 1.51E-Ol 

8.00E+OO 7. 95E-03 8. 13E-02 2.41E-04 1.51E-0l 

9.00E+OO 7. 44E-03 8. 88E-02 8. 87E-05 1.51E-Ol 

1.OOE+Ol 7.00E-03 9. 58E-02 3. 26E-05 1.51E-Ol 

2.00E+Ol 4.90E-03 1. 52E-Ol O.OOE+OO 1.51E-Ol 

3.00E+Ol 4.lOE-03 1.96E-Ol O.OOE+OO 1.51E-0l 

4.00E+Ol 3. 55E-03 2. 34E-Ol O.OOE+OO 1.51E-Ol 

5.00E+Ol 3.09E-03 2.67E-0l O.OOE+OO 1.51E-0l 

6.00E+Ol 2. 69E-03 2. 96E-Ol O.OOE+OO 1.51E-Ol 

7.00E+Ol 2. 34E-03 3.21E-Ol O.OOE+OO 1.51E-Ol 

8.00E+Ol 2.04E-03 3.42E-Ol O.OOE+OO 1.51E-Ol 

9.00E+Ol 1. 17E-03 3.61E-0l O.OOE+OO 1 • .51E-0l 

1.OOE+02 1. 54E-03 3. 78E-Ol O.OOE+OO 1.51E-Ol 

2.00E+02 3. 86E-04 4.60E-0l O.OOE+OO 1.51E-Ol 

3.00E+02 9. 65E-05 4.81E-Ol O.OOE+OO 1.51E-Ol 

4.00E+02 2.41E-05 4. 86E-Ol O.OOE+OO 1.51E-0l 

5.00E+02 6.03E-06 4. 88E-Ol O.OOE+OO I.51E-Ol 

6.00E+02 1.5IE-06 4. 88E-0l O.OOE+OO 1.51E-OI 

7.00E+02 3. 71E':"07 4. 88E-Ol O.OOE+OO 1.5IE-OI ... ; . 8.00E+02 9. 43E-08 4. 88E-Ol O.OOE+OO 1.51E-OI 

9·.00E+02 2. 36E-08 4. 88E-OI O.OOE+OO 1.5IE-Ol 

B-89 
CLASS D AHAD .. 1 HICIlOIi STABLE CADHIDH 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.S9E-Ol 2.26E-Ol 3.03E-04 1.S4E-Ol 6. 39E-Ol 

2.00E-Ol 2.8SE-Ol 2.0lE-Ol 2. 96E-07 1.S2E-Ol 6. 38E-Ol 

3.00E-Ol 3.0BE-Ol 1. 79E-Ol O.OOE+OO 1.49E-Ol 6. 37E-Ol 

4.00E-Ol 3. 28E-Ol 1.60E-Ol O.OOE+OO 1.4SE-Ol 6. 33E-Ol 

S.OOE-Ol 3. 46E-Ol 1. 43E-Ol O.OOE+OO 1.4lE-0l 6. 29E-Ol 

6.00E-Ol 3.6lE-Ol 1. 27E-Ol O.OOE+OO 1.3SE-Ol 6. 23E-Ol 

7.00E-Ol 3.7SE-Ol 1.13E-Ol O.OOE+OO 1. 29E-0l 6.l7E-Ol 

8.00E-Ol 3. 88E-ol 1.OlE-Ol O.OOE+OO 1.22E-Ol 6.11E-Ol 

9.00E-Ol 3. 99E-Ol 8.96E-02 O.OOE+OO 1.16E-Ol 6.04E-Ol 

1.OOE+OO 4.0BE-Ol 7. 97E-02 O.OOE+OO 1.09E-Ol S.97E-Ol 

2.00E+OO 4. 64E-Ol 2. 42E-02 O.OOE+OO 4.9SE-02 S.37E-Ol 

3.00E+OO 4. BlE-Ol 7. 13E-03 O.OOE+OO 1. 97E-02 S.08E-Ol 

4.00E+OO 4.86E-Ol 2.0SE-03 O.OOE+OO 7. 49E-03 4.9SE-Ol 

S.OOE+OO 4. 87E-Ql S.8lE-04 O.OOE+OO 2. 79E-03 4.9lE-Ol 

6.00E+OO 4.B8E-0l 1. 62E-04 O.OOE+OO 1.03E-03 4.B9E-Ol 

7.00E+OO 4.8BE-Ol 4. 47E-OS O.OOE+OO 3.8lE-04 4. 88E-Ol 

8.00E+OO 4. 88E-Ol 1. 22E-OS O.OOE+OO 1.40E-04 4. 88E-Ol 

9.00E+OO 4.BBE-Ol 3. 32E-06 O.OOE+OO S.16E-QS 4.B8E-Ol 

1.OOE+Ol 4.8BE-Ol 8. 96E-07 O.OOE+OO 1.90E-OS 4.B8E-Ol 

2.00E+Ol 4.B7E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.B7E-Ol 

3.00E+Ol 4.B7E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.87E-Ol 

4.00E+Ol 4.87E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.B7E-Ol 

S.OOE+Ol 4. B6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.86E-Ol 

6.00E+Ol 4.B6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 86E-Ol 

7.00E+Ol 4. 86E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 86E-Ol 

8.00E+Ol 4. BSE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. BSE-Ol 

9.00E+Ol 4.8SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 4. BSE-Ol 

1.OOE+02 4. 84E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.B4E-Ol 

2.00E+02 4.8lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. BlE-Ol 

3.00E+02 4.77E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 77E-Ol 

4.00E+02 4. 73E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 73E-Ol 

S.OOE+02 4.70E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.70E-Ol 

6.00E+02 4. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 66E-Ol 

7.00E+02 4. 63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-Ol 

8.00E+02 4.S9E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.S9E-Ol 

9.00E+02 4.S6E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.S6E-Ol .' .. ',1.00E+03 4.S2E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.S2E-Ol ' .. 2.00E+03 4.19E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.19E-Ol 

4.00E+03 3.60E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.60E-Ol 

B.OOE+03 2. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 66E-Ol 

1.OOE+04 2. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.2BE-Ol 

2.00E+04 1.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-Ol 

B-90 
CLASS D MAD .... 1 HICltON STABLE CADKIUH 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-----------------------~- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

.1.00E-Ol 1. 61E-06 6.04E-05 

I 2.00E-Ol 3. 68E-06 7. 33E-04 

3.00E-Ol 5. 93E-06 2.60E-03 

4.00E-Ol 8. 35E-06 5.8lE-03 

5.00E-Ol 1.09E-05 1.02E-02 

6.00E-Ol 1. 36E-05 1.56E-02 

7.00E-Ol 1. 64E-05 2. 18E-02 

8.00E-Ol 1. 93E-05 2. 84E-02 

9.00E-Ol 2. 23E-05 3. 54E-02 

1.00E+OO 2. 53E-05 2. 53E-05 4. 24E-02 4. 24E-02 

2.00E+OO 3. 35E-05 5. 89E-05 5.92E-02 1.02E-Ol 

3.00E+OO 3.60E-05 9. 49E-05 2. 98E-02 1.31E-Ol 

4.00E+OO 3. 68E-05 1. 32E-04 1.22E-02 1.44E-Ol 

5.00E+OO 3.70E-05 1. 69E-04 4.70E-03 1. 48E-Ol 

6.00E+OO 3.70E-05 2.06E-04 1. 76E-03 1.50E-Ol 

7.00E+OO 3.70E-05 2. 43E-04 6. 52E-04 1.51E-Ol 

8.00E+OO 3.70E-05 2.80E-04 2. 41E-04 1.51E-Ol 

9.00E+OO 3.70E-05 3. 17E-04 8. 87E-05 1.51E-Ol 

1.00E+Ol 3.70E-05 3. 54E-04 3. 26E-05 1.51E-0l 

2.00E+Ol 3.70E-05 7.24E-04 O.OOE+OO I.SIE-Ol 

3.00E+Ol 3.70E-05 1.09E-03 O.OOE+OO 1.51E-Ol 

4.00E+Ol 3.70E-05 1. 46E-03 O.OOE+OO 1. 51E-Ol 

5.00E+Ol 3. 69E-05 1. 83E-03 O.OOE+OO 1.51E-Ol 

6.00E+Ol 3. 69E-05 2.20E-03 O.OOE+OO 1.51E-Ol 

7.00E+Ol 3.69E-05 2. 57E-03 O.OOE+OO 1.51E-Ol 

8.00E+Ol 3. 68E-05 2. 94E-03 O.OOE+OO 1.51E-Ol 

9.00E+Ol 3. 68E-05 3. 31E-03 O.OOE+OO 1.51E-Ol 

1.00E+02 3. 68E-05 3. 68E-03 O.OOE+OO 1.51E-Ol 

2.00E+02 3. 65E-05 7. 34E-03 O.OOE+OO 1.51E-Ol 

3.00E+02 3. 62E-05 1.10E-02 O.OOE+OO 1.51E-Ol 

4.00E+02 3.60E-05 1. 46E-02 O.OOE+OO 1.51E-Ol 

5.00E+02 3. 57E-05 1.82E-02 O.OOE+OO 1.51E-Ol 

6.00E+02 3. 54E-05 2. 17E-02 O.OOE+OO 1.51E-Ol 

7.00E+02 3. 52E-05 2. 53E-02 O.OOE+OO 1. 51E-Ol , :" 8.00E+02 3. 49E-05 2. 88E-02 O.OOE+OO 1.51E-Ol 

9.00E+02 3. 46E-05 3. 22E-02 O.OOE+OO 1. 51E.;.OI 

1.00E+03 3. 44E"-05 3. 57E-02 O.OOE+OO 1.51E-Ol 

2.00E+03 3. 18E-05 6. 88E-02 O.OOE+OO 1.51E-Ol 

4.00E+03 2. 74E-05 1. 28E-Ol O.OOE+OO 1.51E-Ol 

8.00E+03 2.02E-05 2. 22E-Ol O.OOE+OO 1. 51E-Ol 

1.00E+04 h 73E-05 2.60E-Ol O.OOE+OO 1.51E-Ol 

2.00E+04 8. 12E-06 3.81E-OI O.OOE+OO 1.51E-Ol 

B-91 
CLASS D AMAD = 1 KICRON HALFLIFE= 1.86E+18 DAYS INDIUM 115 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2.58E-Ol 2. 26E-Ol 3.03E-04 1. 55E-0l 6.39E-Ol 

2.00E-Ol 2. 83E-Ol 2.01E-Ol 2. 96E-07 1. 54E-Ol 6. 38E-Ol 

3.00E-Ol 3.04E-Ol 1.79E-Ol O.OOE+OO 1.53E-0l 6.36E-Ol 

4.00E-Ol 3. 24E-Ol 1.60E-Ol O.OOE+OO 1.49E-Ol 6. 33E-Ol 

5.00E-Ol 3.41E-0l 1. 43E-0l O.OOE+OO 1. 45E-0l 6. 29E-Ol 

6.00E-Ol 3. 57E-Ol 1. 27E-Ol O.OOE+OO 1.40E-Ol 6. 23E-0l 

7.00E-Ol 3.71E-Ol 1.13E-0l O.OOE+OO 1.33E-Ol 6. 17E-Ol 

8.00E-Ol 3. 83E-Ol 1.0IE-Ol O.OOE+OO 1. 27E-Ol 6.10E-Ol 

9.00E-Ol 3. 94E-Ol 8.96E-02 O.OOE+OO 1.20E-Ol 6.03E-Ol 

1.00E+OO 4.04E-Ol 7. 97E-02 O.OOE+OO 1.12E-OI 5. 96E-Ol 

2.00E+OO 4. 59E-Ol 2. 42E-02 O.OOE+OO 5.13E-02 5.35E-0l 

3.00E+OO 4. 76E-Ol 7.13E-03 O.OOE+OO 2.04E-02 5.04E-Ol 

4.00E+OO 4.81E-Ol 2.05E-03 O.OOE+OO 7.77E-03 4.91E-Ol 

5.00E+OO 4. 83E-Ol 5.81E-04 O.OOE+OO 2.90E-03 4. 86E-Ol 

6.00E+OO 4. 83E-Ol 1. 62E-04 O.OOE+OO 1.07E-03 4.84E-Ol 

7.00E+OO 4. 83E-Ol 4.47E-05 O.OOE+OO 3. 95E-04 4. 84E-Ol 

8.00E+OO 4. 83E-Ol 1.22E-05 O.OOE+OO 1. 46E-04 4.83E-Ol 

9.00E+OO 4. 83E-Ol 3. 32E-06 O.OOE+OO 5. 36E-05 4. 83E-Ol 

1.00E+Ol 4.83E-Ol 8. 96E-07 O.OOE+OO 1.97E-05 4.83E-0l 

2.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

3.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.8 

4.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-O 

5.00E+Ol 4.83E-0l O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

6.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

7.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

8.00E+Ol 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

9.00E+Ol 4. 83E-0l O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

1.00E+02 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

2.00E+02 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

3.00E+02 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

4.00E+02 ir'.83E-0l O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

5.00E+02 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

6.00E+02 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

7.00E+02 Ih83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

8.00E+02 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.83E-0l 

9.00E+02 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-0l 

1.OOE+03 4. 83E-0l O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

2.00E+03 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

4.00E+03 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.83E-0l 

8.00E+03 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

1.OOE+04 4.83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

2.00E+04 4. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-Ol 

B-92 
CLASS D AMAD = 1 MICR.ON STABLE nN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------~----------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.3lE-Ol 2. 26E-Ol 3.03E-04 1.SSE-0l 6. 13E-Ol 

2.00E-Ol 2!'29E-Ol 2.01E-Ol 2. 96E-07 1.S4E-01 S.8SE-Ol 

3.00E-Ol 2. 28E-0l 1.79E-OI O.OOE+OO 1. S3E-0l S.60E-Ol 

4.00E-Ol 2. 26E-Ol 1.60E-Ol O.OOE+OO 1. 49E-Ol S.36E-Ol 

S.OOE-Ol 2. 26E-Ol 1. 43E-Ol O.OOE+OO 1.4SE-Ol S.13E-Ol 

6.00E-Ol 2. 26E-Ol 1. 27E-Ol O.OOE+OO 1.40E-Ol 4.92E-Ol 

7.00E-Ol 2. 26E-Ol 1.13E-Ol O.OOE+OO 1. 33E-Ol 4.72E-Ol 

8.00E-Ol 2. 26E-Ol 1.OlE-0l O.OOE+OO 1. 27E-Ol 4.S3E-Ol 

9.00E-Ol 2. 26E-0l 8. 96E-02 O.OOE+OO 1.20E-0l 4.3SE-Ol 

1.OOE+OO 2. 26E-Ol 7. 97E-02 O.OOE+OO l.l2E-Ol 4.l8E-Ol 

2.00E+OO 2.2SE-Ol 2. 42E-02 O.OOE+OO S.13E-02 3.00E-Ol 

3.00E+OO 2.20E-Ol 7.13E-03 O.OOE+OO 2.04E-02 2. 47E-Ol 

4.00E+OO 2. 14E-Ol 2.0SE-03 O.OOE+OO 7. 77E-03 2. 24E-Ol 

S.OOE+OO 2.09E-Ol S.8lE-04 O.OOE+OO 2.90E-03 2.l2E-OI 

6.00E+OO 2.04E-Ol 1. 62E-04 O.OOJt+OO 1.07E-03 2.0SE-Ol 

7.00E+OO 1. 99E-Ol 4. 47E-OS O.OOE+OO 3.9SE-04 2.00E-Ol 

8.00E+OO 1. 96E-0l 1.22E-OS O.OOE+OO 1. 46E-04 1.96E-OI 

9.00E+OO 1. 92E-Ol 3. 32E-06 O.OOE+OO S.36E-OS 1. 92E-Ol 

1.00E+Ol 1. 89E-Ol 8.96E-07 O.OOE+OO 1. 97E-OS 1.89E-0l 

2.00E+Ol 1.70E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.70E-Ol 

3.00E+Ol 1.S9E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1. S9E-Ol 

4.00E+Ol I.S2E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.S2E-Ol 

S.OOE+Ol 1.4SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.4SE-OI 

6.00E+Ol 1.40E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-Ol 

7.00E+Ol 1. 36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 36E-0l 

8.00E+Ol 1.J2E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-Ol 

9.00E+Ol 1. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.28E-OI 

1.00E+02 1.2SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.2SE-OI 

2.00E+02 1.03E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-Ol 

3.00E+02 8. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 63E-02 

4.00E+02 7. 26E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 26E-02 

S.OOE+02 6.l0E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.l0E-02 

6.00E+02 S.13E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.13E-02 

7.00E+02 4. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 32E-02 

8.00E+02 3. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 63E-02 

9.00E+02 3.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.0SE-02 

1.OOE+03 2.S7E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S7E-02 

2.00E+03 4.S4E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.S4E-03 

4.00E+03 1. 42E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 42E-04 

7.00E+03 7.8SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 7.8SE-07 

8.00E+03 1. 39E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-07 

9.00E+03 2. 44E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2. 44E-08 

B-93 
CLASS D AHAD - 1 MICltON STABLE TIN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------ ----------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2. 65E-02 6.06E.,..05 

2.00E-Ol 5. 35E .... 02 7. 39E-04 

3.00E-Ol 7.70E-02 2. 63E-03 

4.00E-Ol 9. 74E-02 5. 88E-03 

5.00E-Ol 1.15E-0l 1.04E-02 

6.00E-Ol 1.31E-Ol 1. 59E-02 

7.00E-Ol 1.45E-Ol 2.22E-02 

8.00E-Ol 1.57E-Ol 2.90E-02 

9.00E-Ol 1.68E-Ol 3.61E-02 

1.OOE+OO 1. 78E-Ol 1. 78E-Ol 4. 34E-02 4. 34E-02 

2.00E+OO 5. 64E-02 2. 34E-Ol 6.11E-02 1.05E-Ol 

3.00E+OO 2.21E-02 2. 56E-Ol 3.08E-02 1. 35E-Ol 

4.,OOE+OO 1.09E-02 2.67E-Ol 1. 27E-02 1.48E-0l 

5.00E+OO 6. 95E-03 2. 74E-Ol 4. 87E-03 1. 53E-Ol 

6.00E+OO 5. 32E-03 2.79E-Ol 1. 83E-03 1.55E-Ol 

7.00E+OO 4.46E-03 2. 84E-Ol 6.77E-04 1. 55E-Ol 

8.00E+OO 3. 88E-03 2.88E-Ol 2.50E-04 1. 56E-Ol 

9.00E+OO 3.43E-03 2.9lE-Ol 9.20E-05 1. 56E-Ol 

1.OOE+Ol 3.06E-03 2. 94E-Ol 3. 39E-05 1.56E-Ol 

2.00E+Ol 1. 35E-03 3.l3E-Ol O.OOE+OO 1. 56E-Ol 

3.00E+Ol 8. 93E-04 3.24E-Ol O.OOE+OO 1.56E-Ol 

4.00E+Ol 6. 99E-04 3. 32E-Ol O.OOE+OO 1. 56E-Ol 

5.00E+Ol 5.77E-04 3.38E-Ol O.OOE+OO 1. 56E-Ol 

6.00E+Ol 4. 88E-04 3. 43E-Ol O.OOE+OO 1. 56E-Ol 

7.00E+Ol 4.21E-04 3. 48E-0l O.OOE+OO 1. 56E-Ol 

8.00E+Ol 3. 69E-04 3. 52E-Ol O.OOE+OO 1. 56E-Ol 

9.00E+Ol 3. 29E-04 3. 55E-Ol O.OOE+OO 1.56E-0l 

1.OOE+02 2. 98E-04 3. 58E-Ol O.OOE+OO 1. 56E-Ol 

2.00E+02 1. 83E-04 3.81E-Ol O.OOE+OO 1.56E-0l 

3.00E+02 1.50E-04 3.97E-Ol O.OOE+OO 1. 56E-Ol 

4.00E+02 1.26E-04 4.11E-Ol O.OOE+OO 1. 56E-Ol 

5.00E+02 1.06E-04 4. 22E-Ol O.OOE+OO 1. 56E-Ol 

6.00E+02 8.90E-05 4. 32E-Ol O.OOE+OO 1.56E-Ol 

7.00E+02 7. 48E-05 4.40E-Ol O.OOE+OO 1. 56E-Ol 

·8.00E+02 6. 29E-05 4.47E-Ol O.OOE+OO 1. 56E-Ol 

9.00E+02 5.29E-05 4. 53E-Ol O.OOE+OO 1. 56E-Ol 

1.OOE+03 4. 45E-05 4.58E-0l O.OOE+OO 1.56E-Ol 

2.00E+03 7.87E-06 4. 79E-Ol O.OOE+OO 1. 56E-Ol 

4.00E+03 2. 49E-07 4.83E-0l O.OOE+OO 1. 56E-Ol 

6.00E+03 1.19E-08 4. 83E-Ol O.OOE+OO 1. 56E-Ol 

B-94 
CLASS D AHA» = 1 MICRON STABLE TELLURIUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.S7E-Ol 2. 26E-Ol 3.03E-04 1.47E-Ol 6.30E-Ol 

2.00E-Ol 2.S0E-Ol 2.0lE-Ol 2. 96E-07 1. 36E-Ol 6.lSE-Ol 

3.00E-Ol 2.96E-0l 1.79E-Ol O.OOE+OO 1.29E-OI 6.0SE-Ol 

4.00E-Ol 3.06E-OI 1.60E-Ol O.OOE+OO 1. 24E-Ol S.90E-Ol 

S.OOE-Ol 3.13E-Ol 1.43E-Ol O.OOE+OO 1.19E-OI S.74E-Ol 

6.00E-Ol 3.lSE-Ol 1.27E-OI O.OOE+OO 1.13E-Ol S.SSE-Ol 

7.00E-Ol 3.21E-Ol 1.13E-OI O.OOE+OO 1.OSE-OI S.4lE-Ol 

S.OOE-Ol 3. 22E-OI 1.OlE-Ol O.OOE+OO 1.02E-OI S.2SE-Ol 

9.00E-OI 3.23E-Ol S.96E-02 O.OOE+OO 9.60E-02 S.OSE-OI 

1.OOE+OO 3. 23E-Ol 7. 97E-02 O.OOE+OO 9.00E-02 4. 92E-Ol 

2.00E+OO 3.00E-Ol 2. 42E-02 O.OOE+OO 4.06E-02 3.6SE-Ol 

3.00E+OO 2. 13E-OI 7.l3E-03 O.OOE+OO 1.6lE-02 2. 97E-Ol 

4.00E+OO 2.SSE-0l 2.0SE-03 O.OOE+OO 6.13E-03 2. 63E-Ol 

S.OOE+OO 2. 44E-Ol S.SIE-04 O.OOE+OO 2.2SE-03 2. 47E-OI 

6.00E+OO 2.36E-OI 1. 62E-04 O.OOE+OO S.4SE-04 2.37E-Ol 

7.00E+OO 2.3IE-Ol 4. 47E-OS O.OOE+OO 3.12E-04 2.3lE-0l 

S.OOE+OO 2. 27E-Ol 1. 22E-OS O.OOE+OO 1.lSE-04 2. 27E-OI 

9.00E+OO 2. 23E-Ol 3. 32E-06 O.OOE+OO 4. 22E-OS 2. 23E-Ol 

1.OOE+Ol 2.20E-Ol S.96E-07 O.OOE+OO 1. SSE-OS 2.20E-Ol 

2.00E+Ol 1. 93E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 93E-OI 

3.00E+OI 1.13E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.73E-Ol 

4.00E+Ol 1.60E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-Ol 

S.OOE+OI 1. SOE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. SOE-Ol 

6.00E+Ol 1.43E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.43E-OI 

7.00E+Ol 1.3SE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.3SE-OI 

S.OOE+Ol 1.3'5E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.3SE-OI 

9.00E+OI 1. 32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.32E-OI 

1.OOE+02 1.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-OI 

2.00E+02 1.2SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.2SE-Ol 

3.00E+02 1.23E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1. 23E-Ol 

4.00E+02 1.21E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.2lE-OI 

S.OOE+02 1.19E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.19E-01 

6.00E+02 1.ISE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.ISE-OI 

7.00E+02 1.16E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.16E-Ol 

S.OOE+02 1.ISE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.ISE-OI 

·9.00E+02 1.l3E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.13E-Ol 

1.OOE+03 1.1lE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.1lE-OI 

2.00E+03 9.70E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.70E-02 

4.00E+03 7.3SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.3SE-02 

S.OOE+03 4. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 22E-02 

I.OOE+04 3.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.20E-02 

2.00E+04 S.OOE-03 O.OOE+OO O.OOE+OO O.OOE+OO B.OOE-03 

B-9S 
CLASS D AKAD = 1 MICRON STABLE TELLURIUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 6. 85E-03 2. 34E-03 

2.00E-Ol 1. 53E-02 5. 81E-03 

3.00E.;,oOl 2. 41E-02 1.05E-02 

4.00E-Ol 3. 29E-02 1. 64E-02 

5.00E-01 4. 17E-02 2. 32E-02 

6.00E-Ol 5.03E-02 3.09E-02 

7.00E-01 5. 87E-02 3.90E-02 

8.00E-Ol 6. 68E-02 4. 75E-02 

9.00E-Ol 7. 46E-02 5.60E-02 

1.00E+00 8. 22E-02 8. 22E-02 6. 45E-02 6. 45E-02 

2.00E+00 5. 85E-02 1. 41E-Ol 6. 89E-02 1.33E-Ol 

3.00E+00 3. 29E-02 1. 74E-Ol 3. 55E-02 1. 69E-Ol 

4.00E+00 1. 75E-02 1.91E-01 1.59E-02 1.85E-Ol 

5.00E+00 9.60E-03 2.01E-Ol 7.04E-03 1. 92E-01 

6.00E+00 5. 79E-03 2.07E-Ol 3.37E-03 1. 95E-Ol 

7.00E+OO 4.01E-03 2.llE-01 1. 87E-03 1. 97E-Ol 

8.00E+00 3. 18E-03 2. 14E-Ol 1. 26E-03 1. 98E-Ol 

9.00E+00 2. 77E-03 2. 17E-01 9. 96E-04 1. 99E-Ol 

1.00E+Ol 2.55E-03 2. 19E-Ol 8.75E-04 2.00E-Ol 

2.00E+Ol 1.73E-03 2. 39E-01 5. 77E-04 2.07E-Ol 

3.00E+Ol 1. 23E-03 2. 54E-Ol 4.lOE-04 2. 12E-01 

4.00E+Ol 8. 73E-04 2. 64E-Ol 2. 91E-04 2. 15E-Ol 

5.00E+01 6. 21E-04 2.71E-0l 2.07E-04 2. 18E-Ol 

6.00E+Ol 4. 43E-04 2. 77E-Ol 1.48E-04 . 2. 19E-Ol 

7.00E+Ol 3. 17E-04 2.80E-01 1.06E-04 2.21E-Ol 

8.00E+Ol 2. 28E-04 2. 83E-Ol 7.60E-05 2.21E-Ol 

9.00E+01 1. 65E-04 2. 85E-Ol 5.51E-05 2. 22E-01 

1.00E+02 1. 21E-04 2. 86E-Ol 4.02E-05 2. 23E-01 

2.00E+02 1. 63E-05 2.90E-ol 5. 43E-06 2.24E-Ol 

3.00E+02 1. 29E-05 2. 92E-Ol 4. 29E-06 2.24E-Ol 

4.00E+02 1. 26E-05 2. 93E-Ol 4.20E-06 2. 25E-Ol 

5.00E+02 1. 24E-05 2. 94E-Ol 4. 14E-06 2. 25E-Ol 

6.00E+02 1. 22E-05 2.96E-Ol 4.08E-06 2. 26E-Ol 

7.00E+02 1.21E-05 2. 97E-Ol 4.03E-06 2. 26E.,..01 

8.00E+02 1. 19E-05 2. 98E-Ol 3.97E-06 2. 27E-Ol 

9.00E+02 1. 17E-05 2. 99E-01 3. 92E-06 2. 27E-Ol 

1.00E+03 1. 16E-05 3.00E-Ol 3. 86E-06 2. 27E-Ol 

2.00E+03 1.0IE-05 3. 11E-Ol 3. 36E-06 2. 31E-Ol 

4.00E+03 7. 64E-06 3. 29E-Ol 2.55E-06 2. 37E-Ol 

8.00E+03 4. 39E-06 3. 52E-Ol 1. 46E-06 2. 45E-Ol 

1.00E+04 3. 32E-06 3.60E-01 1. 11E-06 2. 47E-Ol 

2.00E+04 8. 23E-07 3. 78E-01 2. 77E-07 2. 53E-Ol 

B-96 
CLASS D .AMAD - 1 MICR.OB STABLE IODINE 127 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------~--------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 3.41E-Ol 2. 26E-Ol 3.03E-04 2.17E-02 5. 89E-Ol 

2.00E-Ol 3. 27E-Ol 2.01E-Ol 2. 96E-07 2. 28E-03 5.30E-Ol 

3.00E-Ol 3.01E-Ol 1. 79E-Ol O.OOE+OO 4.lSE-04 4.81E-Ol 

4.00E-Ol 2. 79E-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 4. 39E-Ol 

S.OOE-Ol 2. 62E-Ol 1.43E-Ol O.OOE+OO 1.21E-04 4.0SE-Ol 

6.00E-Ol 2. 49E-Ol 1.27E-Ol O.OOE+OO 8. 47E-OS 3. 76E-Ol 

7.00E-Ol 2. 39E-Ol 1.13E-Ol O.OOE+OO S.98E-OS 3.S2E-Ol 

8.00E-Ol 2.30E-Ol 1.OlE-Ol O.OOE+OO 4. 23E-OS 3.31E-Ol 

9.00E-Ol 2.24E-Ol 8. 96E-02 O.OOE+OO 2.99E-OS 3.l3E-OI 

1.OOE+OO 2.l9E-OI 7. 97E-02 O.OOE+OO 2.l2E-OS 2. 98E-Ol 

2.00E+OO 1.98E-Ol 2. 42E-02 O.OOE+OO 7.04E-07 2. 22E-Ol 

3.00E+OO 1. 93E-Ol 7.l3E-Q3 O.OOE+OO 3. 82E-08 2.01E-Ol 

4.00E+OO 1. 92E-Ol 2.05E-Q3 O.OOE+OO O.OOE+OO 1. 94E-Ol 

S.OOE+OO 1.91E-Ol S.8lE-04 O.OOE+OO O.OOE+OO 1. 92E-Ol 

6.00E+OO 1.91E-0l 1.62E-04 O.OOE+OO O.OOE+OO 1.91E-Ol 

7.00E+OO 1.9lE-Ol 4. 47E-OS O.OOE+OO O.OOE+OO 1.9lE-Q1 

8.00E+OO 1.90E-OI 1. 22E-OS O.OOE+OO O.OOE+OO 1.90E-OI 

9.00E+OO 1.90E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 1.90E-Ol 

1.OOE+Ol 1. 89E-Ol 8. 96E-07 O.OOE+OO O.OOE+OO 1.89E-Ol 

2.00E+Ol 1. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 83E-Ol 

3.00E+Ol 1.7SE-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 75E-Ol 

4.00E+Ol 1. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 66E-Ol 

S.OOE+Ol 1. S7E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.57E-Ol 

6.00E+Ol 1. 49E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 49E-Ol 

7.00E+Ol 1.40E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-OI 

8.00E+Ol 1.3'2E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-Ol 

9.00E+Ol 1. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-Ol 

1.OOE+02 1.l7E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.l7E-Q1 

2.00E+02 6. 39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.39E~02 

3.00E+02 3. 49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 49E-02 

4.00E+02 1.91E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.91E-02 

S.OOE+02 1.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-02 

6.00E+02 S.68E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.68E-03 

7.00E+02 3.lOE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.lOE-03 

8.00E+02 1.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.70E-03 

9.00E+02 9. 26E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 26E-04 

1.OOE+03 S.OSE-04 O.OOE+OO O.OOE+OO O.OOE+OO S.05E-04 

2.00E+03 1.19E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.19E-06 

B-97 
CLASS D AHAD = 1 MICRON STABLE IODINE 127 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI S.OIE-02 O.OOE+OO 

2.00E-OI I.09E-OI O.OOE+OO 

3.00E-OI I.S8E-OI O.OOE+OO 

4.00E-Ol 2.00E-Ol O.OOE+OO 

S.OOE-OI 2. 34E-OI O.OOE+OO 

6.00E-OI 2. 63E-OI O.OOE+OO 

7.00E-Ol 2. 87E-OI O.OOE+OO 

8.00E-Ol 3.08E-OI O.OOE+OO 

9.00E-Ol 3. 26E-Ol O.OOE+OO 

I.OOE+OO 3.4IE-Ol 3.4IE-OI O.OOE+OO O.OOE+OO 

2.00E+OO 7. 63E-02 4.l7E-Ol O.OOE+OO O.OOE+OO 

3.00E+OO 2.lSE-02 4.39E-OI O.OOE+OO O.OOE+OO 

4.00E+OO 6.SlE-03 4.4SE-Ol O.OOE+OO O.OOE+OO 

S.OOE+OO 2.08E-03 4.47E-Ol O.OOE+OO O.OOE+OO 

6.00E+OO 8.09E-04 4. 48E-Ol O.OOE+OO O.OOE+OO 

7.00E+OO 4.7SE-04 4. 48E-Ol O.OOE+OO O.OOE+OO 

8.00E+OO 4.l2E-04 4. 49E-Ol O.OOE+OO O.OOE+OO 

9.00E+OO 4.2SE-04 4.49E-Ol O.OOE+OO O.OOE+OO 

l.OOE+Ol 4.S7E-04 4. SOE-Ol O.OOE+OO O.OOE+OO 

2.00E+Ol 7.3lE-04 4.S6E-Ol O.OOE+OO O.OOE+OO 

3.00E+Ol 8. S4E-04 4. 64E-Ol O.OOE+OO O.OOE+OO 

4.00E+Ol 8.9SE-04 4. 73E-OI O.OOE+OO O.OOE+OO 

S.OOE+Ol 8. 92E-04 4.82E-Ol O.OOE+OO O.OOE+OO 

6.00E+Ol 8. 67E-04 4.9lE-Ol O.OOE+OO O.OOE+OO 

7.00E+Ol 8.3lE-04 4. 99E-OI O.OOE+OO O.OOE+OO 

8.00E+Ol 7.90E-04 S.07E-Ol O.OOE+OO O.OOE+OO 

9.00E+Ol 7. 48E-04 S.lSE-Ol O.OOE+OO O.OOE+OO 

l.OOE+02 7.07E-04 S.22E-Ol O.OOE+OO O.OOE+OO 

2.00E+02 3. 88E-04 S.7SE-Ol O.OOE+OO O.OOE+OO 

3.00E+02 2.l2E-04 6.04E-Ol O.OOE+OO O.OOE+OO 

4.00E+02 l.l6E-04 6.20E-Ol O.OOE+OO O.OOE+OO 

S.OOE+02 6.32E-OS 6. 29E-Ol O.OOE+OO O.OOE+OO 

6.00E+02 3.4SE-OS 6.33E-Ol O.OOE+OO O.OOE+OO 

7.00E+02 I. 88E-OS 6. 36E-Ol O.OOE+OO O.OOE+OO 

8.00E+02 l.03E-OS 6. 37E-Ol O.OOE+OO O.OOE+OO 

9.00E+02 5. 62E-06 6. 38E-Ol O.OOE+OO O.OOE+OO 

l.OOE+03 3.07E-06 6. 39E-Ol O.OOE+OO O.OOE+OO 

B-98 
CLASS D .AHAD = 1 HICltOH BALFLlFE= 5 .. 73E+09 DAYS IODItiE 129 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.41E-Ol 2. 26E-Ol 3.03E-04 2.17E-02 S.89E-OI 

2.00E-Ol 3.27E-Ol 2.0IE-OI 2. 96E-07 2.2SE-03 S.30E-Ol 

3.00E-Ol 3.0lE-Ol 1. 79E-Ol O.OOE+OO 4.lSE-04 4.SlE-Ol 

4.00E-Ol 2. 79E-Ol 1.60E-Ol O.OOE+OO 1.SSE-04 4. 39E-Ol 

S.OOE-Ol 2. 62E-Ol 1.43E-OI O.OOE+OO 1.2lE-04 4.0SE-Ol 

6.00E-Ol 2.49E-Ol 1. 27E-Ol O.OOE+OO S.47E-OS 3. 76E-Ol 

7.00E-Ol 2. 39E-Ol 1. 13E-Ol O.OOE+OO S.9SE-OS 3.S2E-Ol 

S.OOE-Ol 2.30E-Ol I.OlE-OI O.OOE+OO 4. 23E-OS 3.3lE-OI 

9.00E-OI 2. 24E-Ol S.96E-02 O.OOE+OO 2.99E-OS 3.l3E-Ol 

1.OOE+OO 2.l9E-01 7. 97E-02 O.OOE+OO 2.12E-OS 2. 98E-Ol 

2.00E+OO 1.9SE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 2.22E-Ol 

3.00E+OO 1.93E-Ol 7.l3E-03 O.OOE+OO 3.S2E-OS 2.01E-Ol 

4.00E+OO 1. 92E-Ol 2.0SE-03 O.OOE+OO O.OOE+OO 1.94E-OI 

S.OOE+OO 1.91E-Ol S.81E-04 O.OOE+OO O.OOE+OO 1. 92E-Ol 

6.00E+OO 1.9lE-OI 1. 62E-04 O.OOE+OO O.OOE+OO 1.91E-Ol 

7.00E+OO 1.9lE-Ol 4. 47E-OS O.OOE+OO O.OOE+OO 1.9lE-OI 

S.OOE+OO 1.90E-OI 1.22E-OS O.OOE+OO O.OOE+OO 1.90E-Ol 

9.00E+OO 1.90E-OI 3. 32E-06 O.OOE+OO O.OOE+OO 1.90E-Ol 

I.OOE+Ol 1.S9E-Ol S.96E-07 O.OOE+OO O.OOE+OO I.S9E-OI 

2.00E+Ol 1. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO I.S3E-OI 

3.00E+OI 1.7SE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.7SE-0l 

4.00E+Ol 1. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.66E-Ol 

S.OOE+Ol I.S7E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.S7E-Ol 

6.00E+Ol 1.49E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 49E-OI 

7.00E+Ol 1.40E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-OI 

S.OOE+Ol 1. 32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-Ol 

9.00E+Ol 1. 24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-OI 

1.OOE+02 1.17E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.17E-OI 

2.00E+02 6. 39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-02 

3.00E+02 3. 49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 49E-02 

4.00E+02 1.9,lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.9lE-02 

S.OOE+02 1.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.04E-02 

6.00E+02 S.6SE-03 O.OOE+OO O.OOE+OO O.OOE+OO S.6SE-03 

7.00E+02 3.lDE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.l0E-03 

S.OOE+02 1.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.70E-03 

9.00E+02 9. 26E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 26E-04 

1.OOE+03 S.OSE-04 O.OOE+OO O.OOE+OO O.OOE+OO S.OSE-04 

2.00E+03 1.19E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.19E-06 

B-99 
CLASS D AHA]) == 1 HICKON BALFLIFE= 5.73E+09 DAYS IODINE 129 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 S.OlE-02 O.OOE+OO 

2.00E-Ol I.09E-Ol O.OOE+OO 

3.00E-0l 1. SBE-Ol O.OOE+OO 

4.00E-Ol 2.00E-Ol O.OOE+OO 

S.OOE-Ol 2.34E-Ol O.OOE+OO 

6.00E-0l 2. 63E-Ol O.OOE+OO 

7.00E-Ol 2.B7E-Ol O.OOE+OO 

B.OOE-Ol 3.0BE-Ol O.OOE+OO 

9.00E-Ol· 3. 26E-Ol O.OOE+OO 

l.OOE+OO 3.41E-Ol 3.4IE-Ol O.OOE+OO O.OOE+OO 

2.00E+OO 7.63E-02 4.17E-OI O.OOE+OO O.OOE+OO 

3.00E+OO 2.lSE-02 4. 39E-Ol O.OOE+OO O.OOE+OO 

4.00E+OO 6.SlE-03 4.4SE-Ol O.OOE+OO O.OOE+OO 

S.OOE+OO 2.0BE-03 4. 47E-ol O.OOE+OO O.OOE+OO 

6.00E+OO B.09E-04 4. 48E-Ol O.OOE+OO O.OOE+OO 

7.00E+OO 4.7SE-04 4. 48E-ol O.OOE+OO O.OOE+OO 

B.OOE+OO 4.l2E-04 4. 49E-Ol O.OOE+OO O.OOE+OO 

9.00E+OO 4.2SE-04 4.49E-Ol O.OOE+OO O.OOE+OO 

I.OOE+Ol 4.S7E-04 4.S0E-Ol O.OOE+OO O.OOE+OO 

2.00E+Ol 7.3lE-04 4.S6E-Ol O.OOE+OO O.OOE+OO 

3.00E+Ol 8.S4E-04 4. 64E-Ol O.OOE+OO O.OOE+OO 

4.00E+Ol B.9SE-04 4.73E-Ol O.OOE+OO O.OOE+OO 

S.OOE+Ol 8. 92E-04 4.B2E-Ol O.OOE+OO O.OOE+OO 

6.00E+Ol 8. 67E-04 4. 91E-ol O.OOE+OO O.OOE+OO 

7.00E+Ol 8.3lE-04 4. 99E-Ol O.OOE+OO O.OOE+OO 

8.00E+Ol 7.90E-04 S.07E-ol O.OOE+OO O.OOE+OO 

9.00E+Ol 7.48E-04 S.l5E-Ol O.OOE+OO O.OOE+OO 

1.OOE+02 7.07E-04 S.22E-Ol O.OOE+OO O.OOE+OO 

2.00E+02 3.B8E-04 S.75E-0l O.OOE+OO O.OOE+OO 

3.00E+02 2.l2E-04 6.04E-Ol O.OOE+OO O.OOE+OO 

4.00E+02 1.16E-04 6.20E-Ol O.OOE+OO O.OOE+OO 

S.OOE+02 6. 32E-OS 6. 29E-Ol O.OOE+OO O.OOE+OO 

6.00E+02 3.4SE-OS 6.33E-Ol O.OOE+OO O.OOE+OO 

7.00E+02 I.BBE-OS 6. 36E-Ol O.OOE+OO O.OOE+OO 

,', , B.OOE+02 l.03E-OS 6. 37E-Ol O.OOE+OO O.OOE+OO .. ' 9.00E+02 S.62E-06 6.3BE-OI O.OOE+OO O.OOE+OO 

1.OOE+03 3.07E-06 6. 39E-0l O.OOE+OO O.OOE+OO 

B-lOO 
CLASS D AIIAD - 1 MICRON BALPLIFE- 8.04£+00 DAYS IODINE 131 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.3BE-Ol 2.24E-Ol 3.00E-04 2.lSE-02 S.B4E-Ol 

2.00E-Ol 3.2lE-01 1.9BE-Ol 2.91E-07 2. 24E-03 S.2lE-01 

3.00E-Ol 2. 93E-Ol 1.7SE-0l O.OOE+OO 4.0SE-04 4.6BE-Ol 

4.00E-Ol 2.70E-Ol 1.SSE-Ol O.OOE+OO 1. 79E-04 4.2SE-Ol 

S.OOE-Ol 2. SlE-Ol 1. 37E-Ol O.OOE+OO 1.16E-04 3.8BE-Ol 

6.00E-Ol 2.37E-Ol 1.2lE-01 O.OOE+OO 8.04E-OS 3.S7E-Ol 

7.00E-Ol 2.2SE-Ol 1.06E-01 O.OOE+OO S.63E-OS 3.3lE-01 

B.OOE-Ol 2.lSE-01 9.40E-02 O.OOE+OO 3.9SE-OS 3.09E-Ol 

9.00E-Ol 2.07E-Ol 8. 29E-02 O.OOE+OO 2.77E-OS 2.90E-Ol 

1.00E+OO 2.01E-Ol 7.3lE-02 O.OOE+OO 1. 94E-OS 2. 74E-Ol 

2.00E+OO 1. 67E-0l 2.04E-02 O.OOE+OO S.93E-07 1.87E-01 

3.00E+OO 1.49E-01 S.SlE-03 O.OOE+OO 2.9SE-OB 1.SSE-01 

4.00E+00 1. 36E-Ol 1.4SE-03 O.OOE+OO O.OOE+OO 1.37E-01 

S.OOE+OO 1. 24E-Ol 3.77E-04 O.OOE+OO O.OOE+OO 1.2SE-Ol 

6.00E+OO 1.14E-0l 9. 66E-OS O.OOE+OO O.OOE+OO 1. 14E-Ol 

7.00E+00 1.04E-01 2.4SE-OS O.OOE+OO O.OOE+OO 1.04E-Ql 

8.00E+00 9.SSE-02 6.l4E-06 O.OOE+OO O.OOE+OO 9.SSE-02 

9.00E+OO 8. 74E-02 1.S3E-06 O.OOE+OO O.OOE+OO B.74E-02 

1.00E+Ol 8.00E-02 3.79E-07 O.OOE+OO O.OOE+OO 8.00E-02 

2.00E+Ol 3. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.27E-02 

3.00E+0l 1. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.32E-02 

4.00E+Ol S.29E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.29E-03 

S.OOE+Ol 2.11E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.11E-03 

6.00E+Ol 8. 42E-04 O.OOE+OO O.OOE+OO O.OOE+OO B.42E-04 

7.00E+Ol 3.3SE-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.3SE-04 

8.00E+Ol 1. 33E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 33E-04 

9.00E+Ol S.30E-OS O.OOE+OO O.OOE+OO O.OOE+OO S.30E-OS 

1.00E+02 2. lIE-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.11E-OS 

B-IOI 
CLASS D AHAD - 1 MICROR' BALPLII'B- 8.04E+OO DAYS IODINE 131 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-0l 4. 96E-02 O.OOE+OO 

2. OOE-O 1 1.07E-Ol O.OOE+OO 

3.00E-Ol l.54E-Ol O.OOE+OO 

4.00E-Ol 1. 93E-Ol O.OOE+OO 

5.00E-0l 2.24E-0l O.OOE+OO 

6.00E-Ol 2.50E-Ol O.OOE+OO 

7.00E-0l 2.70E-0l O.OOE+OO 

8.00E-Ol 2. 87E-Ol O.OOE+OO 

9.00E-0l 3.0IE-0l O.OOE+OO 

1.00E+OO 3. 13E-Ol 3.13E-Ol O.OOE+OO O.OOE+OO 

2.00E+OO 6. 42E-02 3.51E-0l O.OOE+OO O.OOE+OO 

3.00E+OO 1. 66E-02 3. 39E-Ol O.OOE+OO O.OOE+OO 

4.00E+OO 4.6IE-03 3. 15E-Ol O.OOE+OO O.OOE+OO 

5 .. 00E+OO 1. 35E-03 2. 91E-Ol O.OOE+OO O.OOE+OO 

6.00E+OO 4. 83E-04 2. 67E-Ol O.OOE+OO O.OOE+OO 

7.00E+OO 2.60E-04 2. 45E-0l O.OOE+OO O.OOE+OO 

8.00E+OO 2.07E-04 2. 25E-0l O.OOE+OO O.OOE+OO 

9.00E+OO 1. 96E-04 2.07E-Ol O.OOE+OO O.OOE+OO 

1.00E+Ol 1. 93E-04 1.90E-Ol O.OOE+OO O.OOE+OO 

2.00E+Ol 1.30E-04 8. 13E-02 O.OOE+OO O.OOE+OO 

3.00E+Ol 6. 43E-05 3. 49E-02 O.OOE+OO O.OOE+OO 

4.00E+Ol 2. 84E-05 1.50E-02 O.OOE+OO O.OOE+OO 

5.00E+Ol 1.20E-05 6. 47E-03 O.OOE+OO O.OOE+OO 

6.00E+Ol 4.91E-06 2. 78E-03 O.OOE+OO O.OOE+OO 

7.00E+Ol 1. 99E-06 1. 19E-03 O.OOE+OO O.OOE+OO 

8.00E+Ol 7. 99E-07 5.13E-04 O.OOE+OO O.OOE+OO 

9.00E+Ol 3.19E-07 2.20E-04 O.OOE+OO O.OOE+OO 

1.OOE+02 1. 27E-07 9.41E-05 O.OOE+OO O.OOE+OO 

•• '! >, •• : -, 

B-102 
CLASS D .AHAD = 1 MICRON BALFLIFE= 8.04£+00 DAYS IODINE 131 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED ACCUMULATED 

DAYS THYROID URINE URINE FECES 

I.OOE-OI 2. 13E-02 4. 83E-02 I.30E-03 

2.00E-OI 4.S8E-02 I.04E-OI 3.00E-03 

3.00E-OI 6. 61E-02 I.SOE-01 4.00E-03 

I 4.00E-01 8.2SE-02 1. 88E-01 S.OOE-03 

S.OOE-01 9.S9E-02 2. 18E-01 6.00E-03 

6.00E-OI 1.07E-01 2.43E-01 7.00E-03 

7.00E-01 1. 16E-01 2.63E-01 7.00E-03 

8.00E-01 1.23E-01 2. 79E-01 8.00E-03 

9.00E-OI 1.29E-01 2. 93E-OI 8.00E-03 

I.OOE+OO 1. 33E-01 3.04E-OI 3.04E-01 9.00E-03 

2.00E+OO 1.49E-01 6. 24E-02 3.41E-0l 1.00E-02 

3.00E+OO 1.42E-01 1.62E-02 3. 29E-01 1.00E-02 

4.00E+OO I.31E-01 4. 47E-03 3.06E-01 9.00E-03 

S.OOE+OO 1.20E-01 1.31E-03 2. 83E-01 8.00E-03 

6.00E+OO I.09E-01 3. 29E-04 2.60E-OI 7.00E-03 

.7.00E+OO 9.9SE-02 2.S3E-04 2.38E-01 7.00E-03 

8.00E+OO 9.06E-02 2.0IE-04 2. 19E-0l 6.00E-03 

9.00E+OO 8.2SE-02 1.90E-04 2.01E-01 6.00E-03 

1.00E+01 7.SIE-02 1.88E-04 1. 84E-Ol 6.00E-03 

2.00E+OI 2.9SE-02 1. 27E-04 7.90E-02 2.30E-03 

3.00E+Ol 1. 16E-02 6.2SE-OS 3.39E-02 1.00E-03 

4.00E+Ol 4.60E-03 2. 77E-OS 1. 46E-02 4.00E-04 

S.OOE+01 1. 82E-03 1.16E-OS 6. 28E-03 1.90E-04 

6.00E+Ol 7. 24E-04 4. 78E-06 2.70E-03 8.00E-OS 

7.00E+01 2. 87E-04 1. 93E-06 1. 16E-03 3.00E-OS 

8.00E+01 1. 14E-04 7. 76E-07 4. 98E-04 1.S0E-OS 

9.00E+OI 4.S4E-OS 3.l1E-07 2. 14E-04 6.00E-06 

1.00E+02 1.80E-OS 1. 24E-07 9. 14E-OS 2.70E-06 

, ',' 

...... : 

" .. '. 

B-103 
CLASS D AHAD - 1 KICllON BALFLIFE= 9.58£-02 DAYS 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------

SYSTEMIC 

DAYS ORGANS 

1.OOE-Ol 1. 66E-Ol 

2.00E-Ol 7. 69E-02 

3.00E-Ol 3. 44E-02 

4.00E-Ol 1.SSE-02 

S.OOE-OI 7.0SE-03 

6.00E-Ol 3.2SE-03 

7.00E-OI 1.SlE-03 

S.OOE-OI 7.07E-04 

9.00E-OI 3. 33E-04 

I.OOE+OO I.SSE-04 

2.00E+OO I.03E-07 

CLASS D AHAD ... 1 KICllOH 

TIME AFTER 

SINGLE INTAKE 

SYSTEMIC 

NASAL GI 

LUNGS PASSAGES TRACT 

1.1OE-Ol 1. 47E-04 1.OSE-02 

4. 74E-02 6. 96E-OS S.37E-04 

2.0SE-02 O.OOE+OO 4. 74E-OS 

S.S6E-03 O.OOE+OO 1.02E-OS 

3. S3E-03 O.OOE+OO 3.2SE-06 

I. 66E-03 O.OOE+OO 1.IOE-06 

7.ISE-04 O.OOE+OO 3.7SE-07 

3.09E-04 O.OOE+OO 1.30E-07 

1.33E-04 O.OOE+OO 4. 46E-OS 

S.76E-OS O.OOE+OO 1.S3E-OS 

I. 26E-OS O.OOE+OO O.OOE+OO 

BALFLIFE= 9 • .588-02 .DAYS 

FRACTION OF INITIAL INTAKE IN: 

NON-SYSTEMIC 

IODINE 132 

TOTAL 

BODY 

2. 86E-Ol 

1.2SE-Ol 

S.49E-02 

2. 43E-02 

I.09E-02 

4.9IE-03 

2. 23E-03 

I.02E-03 

4. 67E-04 

2.lSE-04 

1.16E-07 

IODINE 132 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR 

DAYS EXCRETA EXCRETA FECES 

I.OOE-Ol 2. 43E-02 O.OOE-OO 

2.00E-OI 2.S6E-02 O.OOE-OO 

3.00E-OI I.SlE-02 O.OOE-OO 

4.00E-O! 1.llE-02 O.OOE-OO 

S.OOE-O! 6. 29E-03 O.OOE-OO 

6.00E-OI 3. 43E-03 O.OOE-OO 

7.00E-OI I.S2E-03 O.OOE-OO 

8.00E-OI 9.4SE-04 O.OOE-OO 

9.00E-OI 4.SSE-04 O.OOE-OO 

I.OOE+OO 2. 46E-04 2. 46E-04 O.OOE+OO O.OOE-OO 

2.00E+OO 3.9SE-OS 2.ISE-07 O.OOE+OO O.OOE-OO 

B-104 
CLASS D AJW) - 1 MICRON IlALPLIQ- 9.58B-02 DAYS IODINE 132 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED ACCUMULATED 

DAYS THYROID URINE URINE FECES 

I.OOE-OI 9. 99E-Ol 2. 26E-02 6.10E-04 

2.00E-OI I.OIE-02 2. 29E-02 6.60E-04 

l.OOE-OI 6.82E-Ol I.SSE-02 4.12E-04 

I 4.00E-OI l.99E-Ol 9.09E-Ol 2. 42E-04 

5.00E-OI 2.17E-Ol 4. 94E-Ol l.l6E-04 

6.00E-OI 1.14E-Ol 2.S8E-Ol 7. 44E-05 

7.00E-OI S.78E-Q4 1. liE-Ol l.49E-OS 

8.00E-OI 2. 88E-04 6.S2E-04 I. 87E-OS 

9.00E-OI 1.4IE-04 l.21E-04 8.77E-06 

1.OOE+OO 6. 84E-OS I.S6E-04 I.S6E-04 4.6lE-06 

2.00E+OO l.94E-08 1.6SE-08 9.02E-08 2. 64E-09 

B-I05 
CLASS D AHAD - 1 MICRON HALFLlFE= 8.67£-01 DAYS IODINE 133 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 15E-Ol 2.08E-01 2. 79E-04 2.00E-02 5. 44E-01 

2.00E-01 2. 79E-01 1. 72E-01 2. 52E-07 1. 95E-03 4. 52E-01 

3.00E-01 2. 37E-Ol 1. 41E-01 O.OOE+OO 3.27E-04 3. 78E-01 

4.00E-01 2.03E-Ol 1. 16E-01 O.OOE+OO 1.34E-04 3. 19E-Ol 

5.00E-Ol 1. 76E-01 9.56E-02 O.OOE+OO 8.11E-05 2.72E-01 

6.00E-01 1. 54E-01 7. 86E-02 O.OOE+OO 5. 24E-05 2. 33E-01 

7.00E-01 1. 36E-01 6. 46E-02 O.OOE+OO 3.42E-05 2.01E-01 

8.00E-01 1.22E-01 5.31E-02 O.OOE+OO 2. 23E-05 1. 75E-Ol 

9.00E-01 1.09E-01 4. 36E-02 O.OOE+OO 1. 46E-05 1. 53E-Ol 

1.00E+00 9. 83E-02 3. 58E-02 O.OOE+OO 9. 53E-06 1. 34E-Ol 

2.00E+00 4.00E-02 4. 89E-03 O.OOE+OO 1.42E-07 4. 49E-02 

3.00E+00 1. 76E-02 6. 48E-04 O.OOE+OO O.OOE+OO 1. 82E-02 

4.00E+00 7. 84E-03 8. 38E-05 O.OOE+OO O.OOE+oo 7. 93E-03 

5.00E+00 3. 51E-03 1.07E-05 O.OOE+OO O.OOE+OO 3. 52E-03 

6.00E+00 1. 58E-03 1. 34E-06 O.OOE+OO O.OOE+OO 1. 58E-03 

7.00E+00 7.07E-04 1. 66E-07 O.OOE+OO O.OOE+OO 7.08E-04 

8.00E+00 3. 17E-04 2.04E-08 O.OOE+OO O.OOE+oo 3. 17E-04 

9.00E+00 1. 42E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 42E-04 

1.00E+01 6. 39E-05 O.OOE+OO O.OOE+OO O.OOE+oo 6. 39E-05 

2.00E+02 2.08E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2.08E-08 

B-106 
CLASS D AHA» = 1 MICRON IfALFLIFE- 8.67E-ol DAYS IODINE 133 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 4.61E-02 O.OOE+OO 

2.00E-Ol 9. 26E-02 O.OOE+OO 

3.00E-Ol 1.25E-Ol O.OOE+OO 

4.00E-Ol 1. 45E-Ol O.OOE+OO 

5.00E-Ol 1. 57E-Ol O.OOE+OO 

6.00E ... Ol 1. 63E-Ol O.OOE+OO 

7.00E-Ol 1.64E-Ol O.OOE+OO 

8.00E-Ol 1.62E-Ol O.OOE+OO 

9.00E-Ol 1. 59E-Ol O.OOE+OO 

1.OQE+OO 1. 53E-Ol 1. 53E-Ol O.OOE+OO O.OOE+OO 

2.00E+OO 1. 54E-02 8. 43E-02 O.OOE+OO O.OOE+OO 

3.00E+OO 1. 95E-03 3. 98E-02 O.OOE+OO O.OOE+OO 

4.00E+OO 2. 66E-04 1.82E-02 O.OOE+OO O.OOE+OO 

5.00E+OO 3. 82E-05 8.2lE-03 O.OOE+OO O.OOE+OO 

6.00E+OO 6.68E-06 . 3.70E-03 O.OOE+OO O.OOE+OO 

7.00E+OO 1. 76E-06 1. 66E-03 O.OOE+OO D.OOE+OO . 

8.00E+OO 6. 88E-07 7.49E-04 O.OOE+OO O.OOE+OO 

9.00E+OO 3.l9E-07 3. 37E-04 O.OOE+OO O.OOE+OO 

1.OOE+Ol 1. 54E-07 1.52E-04 O.OOE+OO O.OOE+OO 

2.00E+Ol O.OOE+OO 5. 19E-08 O.OOE+OO O.OOE+OO 

B-I07 
CLASS D AHAD = 1 MICRON BALFLIFE= 8.67E-ol DAYS IODINE III 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED ACCUMULATED 

DAYS THYROID URINE URINE FECES 

1.00E-01 1.9SE-02 4.S0E-02 1.20E-03 

2.00E-01 3. 97E-02 9.0IE-02 2.60E-03 

" 3.00E-0l S.34E-02 I.21E-02 3.20E-03 

4.00E-01 6.20E-02 1. 41E-OI 3.70E-03 

S.OOE-01 ' 6.71E-02 1.S3E-0l 4.20E-03 

6.00E-01 6. 97E-02 I.SSE-01 4.S0E-03 

7.00E-01 7.04E-02 I.59E-01 4.S0E-03 

S.OOE-01 6.9SE-02 1.S8E-01 4.S0E-03 

9.00E-0l 6. 79E-02 1. 54E-01 4.40E-03 

1.00E+OO 6.S2E-02 1. 49E-01 1. 49E-OI 4.40E-Ol 

2.00E+OO 3.5SE-02 1. SOE-02 8.50E-02 2.40E-03 

3.00E+OO 1.67E-02 1.90E-03 3.S6E-02 1.20E-03 

4.00E+OO 7.5SE-Ol 2.5SE-04 1. 76E-02 S.20E-04 

S.OOE+OO l.l9E-Ol l.71E-05 7. 98E-03 2.30E-04 

6.00E+OO 1. SlE-03 4.SSE-06 3.60E-03 9.70E-OS 

7.00E+OO 6.7SE-04 1. 76E-06 1. 62E-Ol 4.S0E-OS 

S.OOE+OO 3.01E-04 6. 69E-07 7. 29E-04 2.00E-OS 

9.00E+OO 1.l4E-04 3.10E-07 3.2SE-04 9.S0E-06 

1.00E+01 6.00E-OS 1. SOE-07 1. 47E-04 4.S0E-06 

2. OOE+O 1 1. SSE-OS O.OOE+OO S.04E-OS O.OOE+OO 

8-lOS 
ClASS D AIIAD ... 1 KICR.OH S'lABLE CESIUM 133 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.90E-Ol 2.26E-Ol 3.03E-04 2.l7E-02 6.3BE-Ol 

2.00E-Ol 4. 33E-Ol 2.0lE-01 2. 96E-07 2.2BE-03 6.36E-Ol 

3.00E-Ol 4.SSE-Ol 1.79E-01 O.OOE+OO 4.lSE-Q4 6.3SE-Ol 

4.00E-Ol 4. 73E-Ol 1.60E-01 O.OOE+OO 1. BSE-04 6.33E-Ol 

S.OOE-Ol 4.BBE-Ol 1.43E-01 O.OOE+OO 1.2lE-04 6.3lE-0l 

6.00E-Ol S.02E-Ol 1.27E-01 O.OOE+OO B.47E-OS 6. 29E-Ol 

7.00E-Ol S.14E-0l 1. 13E-Ol O.OOE+OO S.9BE-OS 6.2BE-Ol 

B.OOE-Ol S.2SE-Ol 1.01E-01 O.OOE+OO 4. 23E-OS 6.26E-Ol 

9.00E-Ol S.34E-Ol B.96E-02 O.OOE+OO 2. 99E-OS 6. 24E-Ol 

1.00E+00 S.43E-Ol 7. 97E-02 O.OOE+OO 2.l2E-OS 6.22E-Ol 

2.00E+00 S.BlE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 6.06E-Ol 

3.00E+00 S.BSE-Ol 7.13E-03 O.OOE+OO 3.B2E-OB S.92E-Ol 

4.00E+00 S.79E-Ol 2.0SE-03 O.OOE+OO O.OOE+OO S.BlE-Ol 

S.OOE+OO S.71E-Ol S.BlE-04 O.OOE+OO O.OOE+OO S.72E-Ol 

6.00E+00 S.64E-Ol 1.62E-04 O.OOE+OO O.OOE+OO S.64E-Ol 

7.00E+00 S.SBE-Ol 4. 47E-OS O.OOE+OO O.OOE+OO S.SBE-Ol 

B.OOE+OO S.S3E-Ol 1. 22E-OS O.OOE+OO O.OOE+OO S.S3E-Ol 

9.00E+00 S.4BE-Ol 3. 32E-06 O.OOE+OO O.OOE+OO S.4BE-Ol 

1.00E+Ol S.44E-Ol B.96E-07 O.OOE+OO O.OOE+OO S.44E-Ol 

2.00E+Ol S.OBE-Ol O.OOE+OO O.OOE+OO O.OOE+OO S.OBE-Ol 

3.00E+Ol 4.77E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 77E-Ol 

4.00E+Ol 4.4BE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.4BE-Ol 

S.OOE+Ol 4.2lE-01 O.OOE+OO O.OOE+OO O.OOE+OO 4.2lE-01 

6.00E+Ol 3.9SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.9SE-Ol 

7.00E+Ol 3. 71E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.71E-Ol 

B.OOE+Ol 3. 48E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.4BE-Ol 

9.00E+Ol 3. 27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 27E-Ol 

1.00E+02 3.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.07E-Ol 

2.00E+02 1.64E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.64E-01 

3.00E+02 B.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO B.71E:"02 

4.00E+02 4. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 64E-02 

S.00E+02 2. 47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 47E-02 

6.00E+02 1.32E-02 O.OOE+OO . O.OOE+OO O.OOE+OO 1.32E~02 

7.00E+02 7.0lE-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.0lE-03 

B.00E+02 3.73E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.73E-03 

9.00E+02 1. 99E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 99E-03 

1.00E+03 1.06E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.06E-03 

2.00E+03 1.94E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 94E-06 

B-l09 
CLASS D AHAD = 1 MICRON STABLE CESIUM 133 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-0l 9.20E-04 2.30E-04 

2.00E-01 2. 22E-03 5. 55E-04 

3.00E-01 3.58E-03 8.95E-04 

4.00E-01 4. 97E-03 1. 24E-03 

5.00E-01 6.38E-03 1. 59E-03 

6.00E-01 7.80E-03 1. 95E-03 

7.00E-01 9.22E-03 2.31E-03 

8.00E-Ol 1.06E-02 2. 66E-03 

9.00E-01 I.21E-02 3.02E-03 

1.00E+OO 1. 35E-02 1. 35E-02 3. 37E-03 3. 37E-03 

2.00E+OO 1. 33E-02 2.68E-02 3.32E-03 6.69E-03 

3.00E+OO 1.10E-02 3.7BE-02 2. 76E-03 9.45E-03 

4.00E+OO B.87E-03 4. 67E-02 2. 22E-03 1. 17E-02 

5.00E+OO 7.16E-03 5.3BE-02 1. 79E-03 1. 35E-02 

6.00E+OO 5. 89E-03 5. 97E-02 1.47E-03 1. 49E-02 

7.00E+OO 4. 98E-03 6.47E-02 1. 24E-03 1. 62E-02 

8.00E+OO 4. 32E-03 6.90E-02 I.OBE-03 I.73E-02 

9.00E+OO 3. 85E-03 7. 29E-02 9. 62E-04 1.B2E-02 

I.OOE+Ol 3. 51E-03 7. 64E-02 8.7BE-04 1.91E-02 

2.00E+Ol 2. 59E-03 1.05E-01 6.4BE-04 2. 62E-02 

3.00E+01 2.41E-03 I.30E-01 6.03E-04 3.24E-02 

4.00E+01 2. 27E-03 1. 53E-01 5. 66E-04 3.B2E-02 

5.00E+01 2.13E-03 1.75E-01 5.32E-04 4.37E-02 . 

6.00E+01 2.00E-03 1. 95E-OI 4. 99E-04 4.B8E-02 

7.00E+OI 1.88E-03 2. 15E-01 4.69E-04 5. 36E-02 

8.00E+01 1. 76E-03 2. 33E-01 4.40E-04 5.B2E-02 

9.00E+01 1.65E-03 2.50E-OI 4.13E-04 6. 24E-02 

1.00E+02 1. 55E-03 2. 66E-01 3. 88E-04 6. 64E-02 

2.00E+02 8. 27E-04 3.80E-01 2.07E-04 9. 51E-02 

3.00E+02 4.40E-04 4. 42E-OI 1.lOE-04 1.lOE-Ol 

4.00E+02 2. 35E-04 4.74E-01 5. 86E-05 1. 19E-01 

5.00E+02 1.25E-04 4. 92E-01 3. 12E-05 1. 23E-01 

6.00E+02 6. 65E-05 5.01E-01 1.66E-05 1.25E-OI 

7.00E+02 3. 54E-05 5.06E-01 8.B6E-06 1. 26E-01 

8.00E+02 1. 89E-05 5.08E-01 4.72E-06 1.27E-01 

.. " .f' . 9.00E+02 1.00E-05 5.10E-01 2. 51E-06 1.27E-OI 

I" 

1.00E+03 5. 35E-06 5.10E-01 1.34E-06 1. 28E-01 

B-110 
CLASS D AIIAD = 1 HICRON IIALFLlFE- 1.10K+04 DAYS CESIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.90E-Ol 2. 26E-Ol 3.03E-04 2.l7E-02 6.3SE-Ol 

2.00E-Ol 4.33E-Ol 2.0lE-Ol 2. 96E-07 2.2SE-03 6. 36E-Ol 

3.00E-Ol 4.5SE-Ol 1. 79E-Ol O.OOE+OO 4.lSE-04 6. 35E-Ol 

4.00E-Ol 4.73E-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 6. 33E-Ol 

5.00E-Ol 4.8SE-Ol 1. 43E-Ol O.OOE+OO 1.2lE-04 6.3lE-Ol 

. 6.00E-Ol 5.02E-Ol 1. 27E-Ol O.OOE+OO 8. 47E-OS 6. 29E-Ol 

7.00E-Ol 5.l4E-Ol 1.13E-Ol O.OOE+OO 5.9SE-OS 6.2SE-Ol 

S.OOE-Ol 5.2SE-Ol 1.OlE-Ol O.OOE+OO 4. 23E-OS 6. 26E-Ol 

9.00E-Ol 5. 34E-Ol S.96E-02 O.OOE+OO 2. 99E-OS 6.24E-Ol 

1.OOE+OO S.43E-Ol 7. 97E-02 O.OOE+OO 2.l2E-OS 6. 22E-Ol 

2.00E+OO 5.8lE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 6.06E-Ol 

3.00E+OO S.85E-Ol 7.l3E-03 O.OOE+OO 3.S2E-OS 5. 92E-Ol 

4.00E+OO S.79E-Ol 2.0SE-03 O.OOE+OO O.OOE+OO S.8lE-Ol 

S.OOE+OO 5.71E-Ol S.SOE-04 O.OOE+OO O.OOE+OO 5.72E-Ol 

6.00E+OO S.64E-Ol 1. 62E-04 O.OOE+OO O.OOE+OO S.64E-OI 

7.00E+OO 5.SSE-Ol 4. 47E-OS O.OOE+OO O.OOE+OO S.SSE-Ol 

8.00E+OO S.S3E-Ol 1. 22E-OS O.OOE+OO O.OOE+OO S.S3E-Ol 

9.00E+OO S.4SE-OI 3. 32E-06 O.OOE+OO O.OOE+OO S.48E-Ol 

1.OOE+Ol S.43E-Ol S.96E-07 O.OOE+OO O.OOE+OO S.43E-Ol 

2.00E+Ol 5.08E-Ol O.OOE+OO O.OOE+OO O.OOE+OO S.08E-Ol 

3.00E+Ol 4. 76E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 76E-Ol 

4.00E+Ol 4.47E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.47E-Ol 

S.OOE+Ol 4.l9E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.l9E-Ol 

6.00E+Ol 3. 94E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 94E-Ol 

7.00E+Ol 3. 69E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.69E-Ol 

8.00E+Ol 3.47E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 47E-Ol 

9.00E+Ol 3.2SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.2SE-Ol 

1.OOE+02 3.0SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.0SE-Ol 

2.00E+02 1.6lE-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.6lE-Ol 

3.00E+02 S.SSE-02 O.OOE+OO O.OOE+OO O.OOE+OO S.SSE-02 

4.00E+02 4. 52E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.S2E-02 

S.OOE+02 2. 39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 39E-02 

6.00E+02 1. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.27E-02 

7.00E+02 6.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.70E-03 

8.00E+02 3.SSE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 55E-03 

9.00E+02 1.SSE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.8SE-03 " .. ' -. 1.OOE+03 9. 94E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.94E-04 

2.00E+03 1.71E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.7IE-06 

B-lll 
CLASS D AMAD - 1 MICRON IlALFLIFB- 1.10E+04 DAYS CESIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 9.20E-04 2.30E-04 

2.00E-Ol 2. 22E-03 5.55E-04 

3.00E-Ol 3. 58E-03 8.95E-04 

4.00E-Ol 4. 97E-03 1. 24E-03 

5.00E-01 6.38E-03 1. 59E-03 

6.00E-Ol 7.80E-03 1. 95E-03 

7.00E-Ol 9.22E-03 2.31E-03 

8.00E-Ol 1.06E-02 2. 66E-03 

9.00E-Ol 1.21E-02 3.02E-03 

1.00E+00 1. 35E-02 1.35E-02 3. 37E-03 3. 37E-03 

2.00E+00 1. 33E-02 2. 68E-02 3. 32E-03 6.69E-03 

3.00E+00 1.10E-02 3. 78E-02 2. 76E-03 9. 45E-03 

4.00E+00 8.87E-03 4.67E-02 2. 22E-03 1. 17E-02 

5.00E+00 7. 16E-03 5.38E-02 1. 79E-03 1. 35E-02 

6.00E+00 5. 89E-03 5. 97E-02 1.47E-03 1.49E-02 

7.00E+00 4. 97E-03 6. 47E-02 1. 24E-03 1. 62E-02 

8.00E+00 4. 32E-03 6.90E-02 1.08E-03 1.72E-02 

9.00E+00 3. 85E-03 7. 28E-02 9. 62E-04 1. 82E-02 

1.00E+Ol 3. 51E-03 7. 63E-02 8.77E-04 1.91E-02 

2.00E+Ol 2. 59E-03 1.04E-Ol 6. 48E-04 2. 61E-02 

3.00E+01 2. 41E-03 1.29E-Ol 6.02E-04 3. 23E-02 

4.00E+Ol 2. 26E-03 1. 52E-Ol 5. 65E-04 3.81E-02 

5.00E+Ol 2. 12E-03 1. 74E-Ol 5.30E-04 4. 35E-02 

6.00E+Ol 1.99E-03 1. 95E-Ol 4. 97E-04 4. 86E-02 

7.00E+Ol 1.87E-03 2. 14E-Ol 4. 67E-04 5. 34E"!'" 02 

8.00E+Ol 1. 75E-03 2. 32E-Ol 4. 38E-04 5. 79E-02 

9.00E+Ol 1. 64E-03 2. 48E-Ol 4. 11E-04 6. 21E-02 

1.00E+02 1. 54E-03 2. 64E-Ol 3. 86E-04 6.60E-02 

2.00E+02 8. 16E-04 3.76E-Ol 2.04E-04 9. 39E-02 

3.00E+02 4. 32E-04 4. 33E-Ol 1.08E-04 1.08E-Ol 

4.00E+02 2. 29E-04 4.62E-Ol 5.72E-05 1. 16E-Ol 

5.00E+02 1. 21E-04 4. 76E-Ol 3.03E-05 1. 19E-Ol 

6.00E+02 6.40E-05 4. 82E-Ol 1.60E-05 1.21E-01 

7.00E+02 3. 39E-05 4. 84E-Ol 8. 47E-06 1. 21E-Ol 

8.00E+02 1. 79E-05 4. 83E-Ol 4. 48E-06 1.21E-Ol 

9.00E+02 9. 49E-06 4.81E-Ol 2. 37E-06 1.20E-Ol 

1.00E+03 5.02E-06 4. 79E-Ol 1.26E-06 1.20E-Ol 

B-U2 
CLASS D AHAD - 1 MICRON STABLE BAllIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 1. 16E-01 2. 26E-01 3.03E-04 1.52E-01 4. 93E-01 

2.00E-01 1.21E-01 2.01E-01 2. 96E-07 1. 47E-01 4. 69E-01 

3.00E-01 1.26E-01 1.79E-01 O.OOE+OO 1. 43E-01 4.48E-01 

4.00E-01 1.30E-01 1.60E-01 O.OOE+OO 1. 38E-01 4. 28E-01 

5.00E-01 1.32E-01 1. 43E-01 O.OOE+OO 1.33E-01 4.08E-01 

6.00E-01 1. 33E-01 1.27E-01 O.·OOE+OO 1. 28E-01 3. 88E-01 

7.00E-01 1.34E-01 1. 13E-01 O.OOE+OO 1. 22E-01 3. 69E-01 

8.00E-01 1. 34E-01 1.01E-01 O.OOE+OO 1. 16E-01 3.50E-01 

9.00E-01 1. 33E-01 8. 96E-02 O.OOE+OO 1.09E-01 3. 32E-01 

1.00E+00 1.32E-01 7. 97E-02 O.OOE+OO 1.02E-01 3. 14E-01 

2.00E+00 1. 12E-01 2.42E-02 O.OOE+OO 4. 65E-02 1.82E-01 

3.00E+00 8.80E-02 7. 13E-03 O.OOE+OO 1. 85E-02 1. 14E-01 

4.00E+00 7.02E-02 2.05E-03 O.OOE+OO 7.03E-03 7. 93E-02 

5.00E+00 5.80E-02 5. 81E-04 O.OOE+OO 2. 62E-03 6. 12E-02 

6.00E+00 4.99E-02 1.62E-04 O.OOE+OO 9.69E-04 5.10E-02 

7.00E+00 4. 43E-02 4.47E-05 O.OOE+OO 3. 57E-04 4. 47E-02 

8.00E+00 4.04E-02 1.22E-05 O.OOE+OO 1.32E-04 4.06E-02 

9.00E+00 3.77E-02 3. 32E-06 O.OOE+OO 4. 84E-05 3.77E-02 

1.00E+01 3. 56E-02 8.96E-07 O.OOE+OO 1. 78E-05 3. 56E-02 

2.00E+01 2. 89E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 89E-02 

3.00E+01 2. 76E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.76E-02 

4.00E+01 2. 68E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 68E-02 

5.00E+01 2. 61E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.61E-02 

6.00E+01 2. 54E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 54E-02 

7.00E+01 2. 48E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 48E-02 

8.00E+01 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

9.00E+01 2. 37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 37E-02 

1.00E+02 2. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 32E-02 

2.00E+02 1.95E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.95E-02 

3.00E+02 1. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 73E-02 

4.00E+02 1. 59E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.59E-02 

5.00E+02 1. 49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 49E-02 

6.00E+02 1.41E-02 O.OOE+OO O.OOE+OO O.OOE+oo 1.41E-02 

7.00E+02 1. 34E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 34E-02 

8.00E+02 1.28E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 28E-02 

9.00E+02 1. 23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 23E-02 

1.00E+03 1. 18E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 18E-02 

2.00E+03 8.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.70E-03 

4.00E+03 5. 63E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5. 63E-03 

8.00E+03 2. 95E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 95E-03 

1.00E+04 2. 23E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.23E-03 

2.00E+04 6.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.02E-04 

B-113 
CLASS D AHAD =- 1 HICRON STABLE BAlUUH 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1. 46E-02 1.llE-Ol 

2.00E-Ol 1. 69E-02 1.5lE-Ol 

l.OOE-Ol 1. 88E-02 1.72E-Ol 

4.00E-Ol 2.06E-02 1.9lE-Ol 

5.00E-Ol 2.2lE-02 2.09E-Ol 

6.00E-Ol 2.l6E-02 2.27E-Ol 

7.00E-0l 2. 49E-02 2. 45E-Ol 

8.00E-Ol 2. 62E-02 2.6lE-Ol 

9.00E-Ol 2.73E-02 2.80E-Ol 

1.OOE+OO 2. 84E-02 2. 84E-02 2. 96E-ol 2. 96E-Ol 

2.00E+OO 7.6lE-Ol l.60E-02 1. 25E-Ol 4.21E-Ol 

l.OOE+OO 4.06E-Ol 4.0lE-02 6. 45E-02 4. 85E-Ol 

4.00E+OO 2. 29E-Ol 4. 24E-02 l.2lE-02 5.l7E-Ol 

5.00E+OO 1.l7E-Ol 4.l7E-02 1. 67E-02 5.l4E-Ol 

6.00E+OO 8.60E-04 4. 46E-02 9.l9E-Ol 5. 44E-Ol 

7.00E+OO 5. 67E-04 4. 52E-02 5. 72E-Ol 5. 49E-Ol 

8.00E+OO l.9lE-04 4. 56E-02 l.74E-Ol 5.5lE-Ol 

9.00E+OO 2. 79E-04 4. 58E-02 2. 59E-Ol 5. 56E-Ol 

1.OOE+Ol 2.05E-04 4.60E-02 1. 87E-Ol 5.57E-Ol 

2.00E+Ol 2.l4E-05 4. 67E-02 2.10E-04 5. 64E-Ol 

l.OOE+Ol 9. 24E-06 4. 68E-02 8.l2E-05 5. 65E-Ol 

4.00E+Ol 7.47E-06 4. 69E-02 6.7lE-05 5. 65E-Ol 

5.00E+Ol 6. 88E-06 4.70E-02 6.l9E-05 5.66E-0l 

6.00E+Ol 6.4lE-06 4.71E-02 5. 78E-05 5. 67E-Ol 

7.00E+Ol 6.02E-06 4.71E-02 5.4lE-05 5. 67E-Ol 

8.00E+Ol 5.6lE-06 4. 72E-02 5.07E-05 5. 68E-Ol 

9.00E+Ol 5. 28E-06 4.72E-02 4. 75E-05 5. 68E-Ol 

1.OOE+02 4. 96E-06 4.7lE-02 4. 46E-05 5. 69E-Ol 

2.00E+02 2.75E-06 4.77E-02 2. 48E-05 5. 72E-Ol 

3.00E+02 1.70E-06 4. 79E-02 1.5lE-05 5. 74E-Ol 

4.00E+02 1.17E-06 4.80E-02 1.05E-05 5. 75E-Ol 

5.00E+02 8. 89E-07 4.8lE-02 8.00E-06 5. 76E-Ol 

6.00E+02 7.26E-07 4. 82E-02 6.5lE-06 5.77E-Ol 

7.00E+02 6.22E-07 4.8lE-02 5. 59E-06 5. 77E-Ol 

8.00E+02 5. 48E-07 4.8lE-02 4.9lE-06 5.78E-Ol 

9.00E+02 4. 92E-07 4. 84E-02 4.4lE-06 5. 78E-Ol 

1'.OOE+Ol 4. 47E-(}7 4. 84E-02 4.02E-06 5. 79E-Ol 

2.00E+Ol 2. 27E-07 4. 87E-02 2.04E-06 5. 82E-Ol 

4.00E+Ol 1.07E-07 4.90E-02 9.60E-07 5. 84E-Ol 

7.00E+Ol 5.l5E-08 4.9lE-02 4. 62E-07 5. 86E-Ol 

8.00E+Ol 4. 26E-08 4.9lE-02 l.82E-07 5.87E-Ol 

1.OOE+04 l.06E-08 4. 94E-02 2.7lE-07 5. 88E-Ol 

B-114 
CLASS D AHAD - 1 MICRON B.A.LFLIFE"'" 1.27£+01 DAYS BAllIUM 140 

TIME AFTER FRACTION 0F INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 1.1SE-01 2.2SE-01 3.01E-04 1. SlE-Ol 4.91E-01 

2.00E-01 1.20E-01 1. 99E-01 2. 92E-07 1.4SE-01 4. 64E-01 

3.00E-01 1.24E-01 1. 77E-01 O.OOE+OO 1.40E-01 4.41E-01 

4.00E-01 1. 27E-01 1. S7E-01 O.OOE+OO 1.3SE-01 4. 19E-01 

5.00E-01 1. 28E-01 1. 39E-01 O.OOE+OO 1.30E-01 3. 97E-01 

6.00E-01 1.29E-01 1. 23E-01 O.OOE+OO 1. 24E-01 3. 76E-01 

7.00E-01 1.29E-01 1.09E-01 O.OOE+OO 1. 17E-01 3.SSE-01 

8.00E-01 1. 28E-01 9. 64E-02 O.OOE+OO 1.l1E-01 3.3SE-01 

9.00E-01 1. 27E-Ol 8.S3E-02 O.OOE+OO 1.04E-01 3. 16E-01 

1.00E+OO 1.2SE-01 7.SSE-02 O.OOE+OO 9.69E-02 2. 98E-01 

2.00E+OO 1.00E-01 2. 17E-02 O.OOE+OO 4. 17E-02 1. 63E-01 

3.00E+OO 7. 48E-02 6.06E-03 O.OOE+OO 1. S7E-02 9.6SE-02 

4.00E+OO S.6SE-02 1.6SE-03 O.OOE+OO S.6SE-03 6. 38E-02 

5.00E+OO 4.42E-02 4. 42E-04 O.OOE+OO 2.00E-03 4. 67E-02 

6.00E+OO 3.60E-02 1. 17E-04 O.OOE+OO 6. 99E-04 3. 68E-02 

7.00E+OO 3.03E-02 3.06E-OS O.OOE+OO 2. 44E-04 3.0SE-02 

8.00E+OO 2. 62E-02 7. 92E-06 O.OOE+OO 8.S2E-OS 2. 63E-02 

9.00E+OO 2. 31E-02 2.04E-06 O.OOE+OO 2. 97E-OS 2.31E-02 

1.00E+01 2.07E-02 S.20E-07 O.OOE+OO 1.03E-OS 2.07E-02 

2.00E+01 9. 74E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9. 74E-03 

3.00E+01 S.39E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5. 39E-03 

4.00E+01 3.04E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.04E-03 

5.00E+01 1. 72E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.72E-03 

6.00E+01 9.71E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.71E-04 

7.00E+01 S.SOE-04 O.OOE+OO O.OOE+OO O.OOE+OO S.SOE-04 

8.00E+01 3. 12E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3. 12E-04 

9.00E+01 1.77E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.77E-04 

1.00E+02 1.00E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E-04 

2.00E+02 3. 66E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3,!66E-07 

B-115 
CLASS D AHAD = 1 MICRON BALFLIFE= 1.27E+Ol DAYS BAR.IUH 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.45E-02 1.30E-Ol 

2.00E-Ol 1. 67E-02 1.51E-Ol 

3.00E-Ol 1.85E-02 1. 69E-Ol 

4.00E-Ol 2.01E-02 1.87E-Ol 

S.OOE-Ol 2.15E-02 2.04E-Ol 

6.00E-Ol 2. 28E-02 2.20E-Ol 

7.00E-Ol 2.40E-02 2. 36E-Ol 

8.00E-Ol 2.S0E-02 2.S2E-Ol 

9.00E-Ol 2.60E-02 2. 67E-Ol 

1.OOE+OO 2.69E-02 2. 69E-02 2.81E-Ol 2.81E-Ol 

2.00E+OO 6. 84E-03 3. 23E-02 1.12E-0l 3. 78E-Ol 

3.00E+OO 3. 45E-03 3.41E-02 S.48E-02 4.12E-Ol 

4.00E+OO 1.S4E-03 3.41E-02 2.S8E-02 4.16E-Ol 

S.OOE+OO 1.04E-03 3. 33E-02 1.27E-02 4.07E-Ol 

6.00E+OO 6.20E-04 3. 22E-02 6. 77E-03 3. 92E-Ol 

7.00E+OO 3.S8E-04 3.09E-02 3.91E-03 3. 75E-Ol 

8.00E+OO 2. 53E-04 2. 95E-02 2. 42E-03 3. 58E-Ol 

9.00E+OO 1.71E-04 2. 81E-02 1. S9E-03 3.40E-Ol 

1.OOE+0l 1.19E-04 2.67E-02 1.09E-03 3.24E-Ol 

2.00E+Ol 7. 87E-06 1. 57E-02 7.08E-OS 1.90E-Ol 

3.00E+Ol 1.81E-06 9. 16E-03 1. 63E-05 1.10E-Ol 

4.00E+Ol 8.48E-07 5.l2E-Ol 7.6lE-06 6. 42E-02 

5.00E+Ol 4. 53E-07 3.09E-03 4.0SE-06 3. 73E-02 

6.00E+Ol 2.46E-07 1.80E-03 2.21E-06 2.17E-02 

7.00E+Ol 1.3lE-07 1.05E-03 1.20E-06 1. 26E-02 

8.00E+Ol 7. 25E-OS 6.07E-04 6.53E-07 7.31E-03 

9.00E+Ol l.95E-OS 3. 53E-04 3. 55E-07 4. 25E-03 

1.OOE+02 2.15E-OS 2.05E-04 1. 93E-07 2. 47E-03 

.) ,-" ' 

B-U6 
CLASS D AHAD - 1 HICR.OH STABLE I..AHTIWftJH 139 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.57E-0l 2.26E-Ol 3.03E-04 1. 56E-Ol 6. 39E-Ol 

2.00E-Ol 2.BlE-Ol 2.0lE-OI 2. 96E-07 1.56E-0l 6.3BE-Ol 

3.00E-Ol 3.02E-Ol 1.79E-Ol O.OOE+OO 1. 55E-Ol 6. 36E-Ol 

I 4.00E-Ol 3.2lE-Ol 1.60E-Ol O.OOE+OO 1. 52E-Ol 6. 33E-Ol 

5.00E-Ol 3.3BE-Ol . 1.43E-Ol O.OOE+OO 1.4BE-Ol 6. 29E-Ol 

6.00E-0l 3. 54E-Ol 1. 27E-Ol O.OOE+OO 1. 42E-Ol 6. 23E-Ol 

7.00E-Ol 3.6BE-Ol 1. 13E-Ol O.OOE+OO 1.36E-OI 6.l7E-OI 

B.OOE-Ol 3.80E-Ol 1.OlE-Ol O.OOE+OO 1.29E-Ol 6.l0E-Ol 

9.00E-0l 3.9lE-Ol B.96E-02 O.OOE+OO 1.22E-Ol 6.02E-Ol 

1.OOE+OO 4.0lE-Ol 7. 97E-02 O.OOE+OO 1.15E-OI 5. 95E-Ol 

2.00E+OO 4. 56E-Ol 2. 42E-02 O.OOE+OO 5.24E-02 S.33E-Ol 

3.00E+OO 4. 73E-Ol 7.l3E-03 O.OOE+OO 2.09E-02 5.0lE-Ol 

4.00E+OO 4.78E-Ol 2.05E-03 O.OOE+OO 7.9SE-03 4.B8E-Ol 

5.00E+OO 4. 79E-Ol 5.8lE-04 O.OOE+OO 2. 96E-03 4. 83E-Ol 

6.00E+OO 4.BOE-Ol 1. 62E-04 O.OOE+OO 1.lOE-03 4.BlE-Ol 

7.00E+OO 4.80E-Ol 4. 47E-05 O.OOE+OO 4.05E-04 4. BOE-Ol 

B.OOE+OO 4.80E-Ol 1.22E-05 O.OOE+OO 1.49E-04 4. BOE-Ol 

9.00E+OO 4.79E-Ol 3. 32E-06 O.OOE+OO 5.4BE-05 4. BOE-Ol 

1.OOE+Ol 4. 79E-Ol 8. 96E-07 O.OOE+OO 2.02E-OS 4. 79E-Ol 

2.00E+Ol 4. 78E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 78E-Ol 

3.00E+Ol 4.77E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 77E-Ol 

4.00E+Ol 4. 77E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 77E-Ol 

5.00E+0l 4.76E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 76E-Ol 

6.00E+Ol 4.7SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.7SE-Ol 

7.00E+Ol 4.74E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 74E-Ol 

B.OOE+Ol 4. 73E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 73E-Ol 

9.00E+Ol 4. 72E-Ol .O.OOE+OO O.OOE+OO O.OOE+OO 4. 12E-Ol 

1.00E+02 4. 11E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.11E-OI 

2.00E+02 4. 62E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.62E-OI 

3.00E+02 4.S3E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.S3E-OI 

4.00E+02 4. 44E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4. 44E-OI 

S.OOE+02 4. 35E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.3SE-Ol 

6.00E+02 4. 27E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-OI 

7.00E+02 4.18E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.IBE-OI 

B.OOE+02 4.10E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.10E-OI 

9.00E+02 4.02E-OI O.OOE+OO O.OOE+OO O.OOE+OO 4.02E-OI . i ., I.OOE+03 3. 94E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 94E-Ol 

2.00E+03 3.23E-OI O.OOE+OO O.OOE+OO O.OOE+OO 3. 23E-Ol 

4.00E+03 2.IBE-OI O.OOE+OO O.OOE+OO O.OOE+OO 2.IBE-0l 

B.OOE+03 9. BSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.B5E-02 

I.OOE+04 6. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 63E-02 

2.00E+04 9.16E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.l6E-03 

B-117 
CLASS D MAD == 1 MICRON STABLE I..ARTBARUH 139 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 4.18E-06 6.07E-05 

2.00E-OI 9.5IE-06 7.42E-04 

3.00E-OI 1. 53E-05 2. 64E-03 

4.00E-Ol 2. 15E-05 5. 93E-03 

5.00E-OI 2.80E-05 I.05E-02 

6.00E-OI 3. 49E-05 I.6IE-02 

7.00E-Ol 4.20E-05 2. 25E-02 

8.00E-OI 4. 94E-05 2. 94E-02 

9.00E-Ol 5.70E-05 3. 66E-02 

I.OOE+OO 6. 49E-05 6. 49E-05 4.40E-02 4.40E-02 

2.00E+OO 8. 58E-05 1.51E-04 6. 24E-02 1.06E-Ol 

3.00E+OO 9. 23E-05 2.4JE-04 3.15E-02 1. 38E-OI 

4.00E+OO 9. 42E-05 3. 37E-04 I.30E-02 I.5IE-OI 

5.00E+OO 9. 48E-05 4. 32E-04 4. 98E-03 1. 56E-OI 

6.00E+OO 9. 49E-05 5. 27E-04 1. 87E-03 1. 58E-OI 

7.00E+OO 9.50E-05 6. 22E-04 6. 92E-04 1. 58E-OI 

8.00E+OO 9.50E-05 7.17E-04 2.56E-04 1. 59E-OI 

9.00E+OO 9. 49E-05 8.12E-04 9.4IE-05 I.S9E-OI 

I.OOE+OI 9. 49E-05 9.07E-04 3. 47E-05 1. 59E-OI 

2.00E+OI 9. 47E-05 1. 86E-03 O.OOE+OO 1. S9E-OI 

3.00E+OI 9. 46E-05 2.80E-03 O.OOE+OO 1. 59E-OI 

4.00E+OI 9. 44E-05 3.7SE-03 O.OOE+OO I.59E-OI 

5.00E+OI 9. 42E-OS 4. 69E-03 O.OOE+OO 1. 59E-OI 

6.00E+OI 9.40E-05 5. 63E-03 O.OOE+OO 1. 59E-OI 

7.00E+OI 9. 38E-OS 6. 57E-03 O.OOE+OO 1. 59E-OI 

8.00E+OI 9. 36E-05 7.5IE-03 O.OOE+OO I.S9E-OI 

9.00E+OI 9. 34E-05 8. 44E-03 O.OOE+OO I.S9E-OI 

I.OOE+02 9. 33E-05 9. 37E-03 O.OOE+OO 1. 59E-OI 

2.00E+02 9.14E-05 1. 86E-02 O.OOE+OO I.S9E-OI 

3.00E+02 8. 96E-05 2.77E-02 O.OOE+OO 1. 59E-OI 

4.00E+02 8. 79E-05 3.6SE-02 O.OOE+OO 1. 59E-OI 

5.00E+02 8. 62E-05 4.S2E-02 O.OOE+OO 1. 59E-OI 

6.00E+02 8. 45E-OS 5. 38E-02 O.OOE+OO 1. 59E-OI 

7.00E+02 8. 28E-05 6.2IE-:02 O.OOE+OO 1. 59E-OI 

'. >t." 8.00E+02 8.12E-OS 7.03E-02 O.OOE+OO 1. 59E-OI 

9.00E+02 7. 96E-OS 7. 84E-02 O.OOE+OO 1. S9E-OI 

I.OOE+03 7.80E-OS· 8. 62E-02 O.OOE+OO 1. 59E-Ol 

2.00E+03 6.40E-OS 1. S7E-OI O.OOE+OO I.S9E-OI 

4.00E+03 4.3IE-OS 2. 63E-OI O.OOE+OO I.S9E-OI 

8.00E+03 I.9SE-OS 3. 82E-OI O.OOE+OO I.S9E-OI 

I.OOE+04 I.3IE-05 4.14E-OI O.OOE+OO 1. S9E-OI 

2.00E+04 I.8IE-06 4.71E-OI O.OOE+OO 1. 59E-OI 

B- 118 
CLASS D AHA» - 1 KICR.ON BALFLIFE- 1.68E+OO DAYS IANTBANDM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 47E-Ol 2.llE-Ol 2.90E-04 1.SOE-0l 6.13E-Ol 

2.00E-Ol 2.S9E-Ol 1. SSE-Ol 2.72E-07 1. 44E-Ol S.SSE-Ol 

3.00E-Ol 2. 67E-Ol 1.S9E-Ol O.OOE+OO 1. 37E-Ol S.62E-Ol 

4.00E-Ol 2. 72E-Ol 1. 36E-Ol O.OOE+OO 1.29E-Ol S.37E-Ol 

S.OOE-Ol 2.7SE-Ol 1.16E-Ol O.OOE+OO 1.20E-Ol S.llE-Ol 

6.00E-Ol 2. 76E-Ol 9.9lE-02 O.OOE+OO 1.llE-Ol 4.S6E-Ol 

7.00E-Ol 2.7SE-Ol S.47E-02 O.OOE+OO 1.02E-Ol 4. 62E-Ol 

S.OOE-Ol 2.73E-Ol 7. 23E-02 O.OOE+OO 9.2SE-02 4.3SE-Ol 

9.00E-Ol 2. 69E-Ol 6.lSE-02 O.OOE+OO S.4lE-02 4.l5E-Ol 

1.OOE+OO 2.6SE-Ol 5. 27E-02 O.OOE+OO 7. 59E-02 3. 94E-Ol 

2.00E+OO 2.00E-Ol 1.06E-02 O.OOE+OO 2.30E-02 2. 33E-Ol 

3.00E+OO 1. 37E-Ol 2.07E-03 O.OOE+OO 6.06E-03 1. 45E-Ol 

4.00E+OO 9.l6E-02 3. 93E-04 O.OOE+OO 1.S2E-03 9. 35E-02 

5.00E+OO 6.0SE-02 7.36E-OS O.OOE+OO 3. 76E-04 6.l2E-02 

6.00E+OO 4.02E-02 1.36E-05 O.OOE+OO 9.20E-OS 4.03E';'02 

7.00E+OO 2. 66E-02 2.4SE-06 O.OOE+OO 2. 24E-05 2. 66E-02 

S.OOE+OO 1.76E-02 4.49E-07 O.OOE+OO S.47E-06 1. 76E-02 

9.00E+OO 1.16E-02 S.07E-OS O.OOE+OO 1. 33E-06 1.16E-02 

1.OOE+Ol 7.70E-03 1. 44E-OS O.OOE+OO 3.24E-07 7.70E-03 

2.00E+Ol 1. 24E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-04 

3.00E+0l 1.9SE-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.9SE-06 

4.00E+Ol 3.lSE-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.lSE-08 

. '".' 

B-1l9 
CLASS D AHAD = 1 HICIlOR IlALPLIFE= 1.688+00 DAYS IAN'.l'IWIU.K 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.0lE-06 5. 83E-05 

2.00E-Ol 8. 76E-06 6. 83E-04 

3.00E-0l 1. 35E-05 2. 34E-03 

4.00E-Ol 1. 82E-05 5.03E-03 

5.00E-Ol 2. 28E-05 8. 53E-03 

6.00E-Ol 2. 72E-05 1. 26E-02 

7.00E-Ol 3.l5E-05 1.68E-02 

8.00E-Ol 3. 55E-05 2.11E-02 

9.00E-Ol 3. 93E-05 2. 53E-02 

1.OOE+OO 4. 29E-05 4. 29E-05 2.9lE-02 2.9lE-02 

2.00~+OO 3. 76E-05 6.60E-05 2.73E-02 4. 66E-02 

3.00E+OO 2. 67E-05 7.04E-05 9.l3E-03 3. 99E-02 

4.00E+OO 1.8lE-05 6. 46E-05 2. 48E-03 2. 89E-02 

5.00E+OO 1.20E-05 5. 48E-05 6. 32E-04 1. 98E-02 

6.00E+OO 7. 96E-06 4. 42E-05 1.57E-04 1. 32E-02 

7.00E+OO 5. 27E-06 3. 45E-05 3. 84E-05 8. 79E-03 

8.00E+OO 3. 49E-06 2.63E-05 9. 38E-06 5. 83E-03 

9.00E+OO 2.3lE-06 1. 97E-05 2. 29E-06 3. 86E-03 

1.OOE+Ol 1. 53E-06 1.46E-05 5.57E-07 2. 55E-03 

2.00E+Ol 2. 45E-08 4. 79E-07 O.OOE+OO 4.lOE-05 

B...,}20 
CLASS D AHAD -= 1 MICRON STABLE GADOLINlmI 157 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 2.46E-Ol 2. 26E-Ol 3.03E-04 1.56E-Ol 6. 28E-Ol 

2.00E-Ol 2. 58E-Ol 2.0lE-Ol 2. 96E-07 1. 56E-Ol 6.l5E-Ol 

3.00E-Ol 2. 69E-Ol 1.79E-Ol O.OOE+OO 1.55E-Ol 6.03E-Ol 

4.00E-Ol 2. 79E-Ol 1.60E-Ol O.OOE+OO 1. 52E-Ol 5.9lE-Ol 

5.00E-Ol 2. 89E-Ol 1.43E-Ol O.OOE+OO 1.48E-Ol 5.79E-Ol 

6.00E-Ol 2. 98E-Ol 1. 27E-Ol O.OOE+OO 1.42E-Ol 5. 67E-Ol 

7.00E-Ol 3.06E-Ol 1.13E-0l O.OOE+OO 1.36E-Ol S.S5E-Ol 

8.00E-OI 3.l3E-Ol 1.OlE-Ol O.OOE+OO 1.29E-OI 5. 43E-Ol 

9.00E-Ol 3.l9E-OI 8. 96E-02 O.OOE+OO 1.22E-0l S.3lE-Ol 

1.OOE+OO 3. 25E-OI 7. 97E-02 O.OOE+OO 1.15E-Ol 5.20E-Ol 

2.00E+OQ 3. 58E-Ol 2. 42E-02 O.OOE+OO 5.2SE-02 4.35E-Ol 

3.00E+OO 3. 68E-Ol 7.l3E-03 O.OOE+OO 2.09E-02 3. 96E-Ol 

4.00E+OO 3.70E-0l 2.05E-03 O.OOE+OO 7. 95E-03 3.80E-Ol 

5.00E+OO 3.70E-Ol 5.8lE-04 O.OOE+OO 2. 97E-03 3. 74E-Ol 

6.00E+OO 3. 69E-Ol 1.62E-04 O.OOE+OO l.lOE-03 3.71E-0l 

7.00E+OO 3. 69E-Ol 4. 47E-05 O.OOE+OO 4.05E-04 3. 69E-Ol 

8.00E+OO 3. 68E-Ol 1.22E-05 O.OOE+OO 1. 49E-04 3. 68E-Ol 

9.00E+OO 3. 68E-Ol 3. 32E-06 O.OOE+OO 5. 49E-05 3. 68E-Ol 

I.OOE+Ol 3.67E-Ol 8.96E-07 O.OOE+OO 2.02E-05 3.67E-Ol 

2.00E+Ol 3. 62E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 62E-Ol 

3.00E+Ol 3.60E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.60E-Ol 

4.00E+Ol 3. 58E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 58E-Ol 

5.00E+Ol 3.57E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.57E-0l 

6.00E+Ol 3. 56E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 56E-Ol 

7.00E+Ol 3.5SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 55E-Ol 

8.00E+Ol 3.5SE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 55E-Ol 

9.00E+Ol 3. 54E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 54E-Ol 

I.OOE+02 3. 53E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 53E-Ol 

2.00E+02 3.46E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 46E-OI 

3.00E+02 3. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 39E-Ol 

4.00E+02 3. 33E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 33E-Ol 

S.OOE+02 3.26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.26E-Ol 

.6.00E+02 3.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.20E-Ol 

7.00E+02 3.l4E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.l4E-OI 

8.00E+02 3.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.07E-0l 

9.00E+02 3.0lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.0lE-Ol 

1.OOE+03 2.95E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 95E-Ol 

2.00E+03 2. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-Ol 

4.00E+03 1. 63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 63E-Ol 

8.00E+03 7.39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 39E-02 

1.OOE+04 4.97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 97E-02 

2.00E+04 6.87E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 87E-03 

B-121 
CLASS D AHAD ... 1 MICRON STABLE GAOOLINIUM 157 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.lSE-02 6.07E-OS 

2.00E-01 2. 31E-02 7. 42E-04 

3.00E-01 3. 32E-02 2. 64E-03 

4.00E-01 4. 19E-02 S.93E-03 

S.OOE-OI 4.9SE-02 1.0SE-02 

6.00E-01 S.61E-02 1.61E-02 

7.00E-Ol 6.19E-02 2. 25E-02 

S.OOE-OI 6.70E-02 2. 94E-02 

9.00E-Ol 7. 15E-02 3. 67E-02 

1.00E+OO 7. 56E-02 7. 56E-02 4.40E-02 4.40E-02 

2.00E+OO 2. 23E-02 9. 79E-02 6. 24E-02 1.06E-01 

3.00E+OO 7.47E-03 I.05E-01 3.16E-02 1.3SE-OI 

4.00E+OO 2.S5E-03 1.0SE-01 1.30E-02 I.51E-0l 

5.00E+OO I.41E-03 . I.lOE-Ol 4. 99E-03 1.S6E-01 

6.00E+OO 9. 44E-04 1.lIE-Ol 1.87E-03 1.5SE-01 

7.00E+OO 7. 76E-04 I.lIE-OI 6. 93E-04 1. 59E-01 

S.OOE+OO 6. 98E-04 1. 12E-01 2.S6E-04 1.59E-OI 

9.00E+OO 6.47E-04 1.BE-OI 9.42E-OS 1. 59E-OI 

1.00E+01 6.06E-04 1.BE-01 3.47E-OS 1.59E...,OI 

2.00E+01 3.3SE-04 1. ISE-01 O.OOE+OO 1. 59E-01 

3.00E+OI 2.05E-04 1.20E-01 O.OOE+OO· 1. S9E-01 

4.00E+01 1. 38E-04 1. 22E-OI O.OOE+OO 1. 59E-Q1 

5.00E+0l I.04E-04 1.23E-01 O.OOE+OO 1.S9E-01 

6.00E+01 8.72E-05 1.24E-01 O.OOE+OO 1. 59E-01 

7.00E+01 7. 87E-05 1.25E-01 O.OOE+OO 1. 59E-01 

8.00E+OI 7. 44E-05 1. 26E-01 O.OOE+OO 1. 59E-01 

9.00E+01 7. 22E-05 1. 26E-OI O.OOE+OO 1.59E-01 

1.00E+02 7.l0E-05 1.27E-01 O.OOE+OO 1. 59E-01 

2.00E+02 6. 86E-OS 1. 34E-Ol O.OOE+OO 1.S9E-0l 

3.00E+02 6. 72E-05 1.41E-01 O.OOE+OO 1.S9E-01 

4.00E+02 6. 59E-OS 1.47E-01 O.OOE+OO 1.59E-01 

5.00E+02 6.46E-05 1. 54E-01 O.OOE+OO 1.59E-01 

6.00E+02 6. 33E-OS 1.60E-01 O.OOE+OO 1.59E-01 

7.00E+02 6. 21E-05 1.67E-01 O.OOE+OO 1.S9E-01 

8;OOE+02 6.09E-OS 1.73E-01 O.OOE+OO 1. ~9E-01 

9.00E+02 5. 97E-05 1.79E-01 O.OOE+OO 1.S9E-01 

1.00E+03 S.S5E-05 1. S5E-01 O.OOE+OO 1. 59E-01 

2.00E+03 4.80E-05 2. 38E-01 O.OOE+OO 1. 59E-01 

4.00E+03 3. 23E-05 3. 17E-01 O.OOE+OO 1. 59E-01 

8.00E+03 1. 46E-05 4.06E-01 O.OOE+OO 1. S9E-01 

1.00E+04 9. 85E-06 4.30E-01 O.OOE+OO 1.59E-01 

2.00E+04 1.37E-06 4. 73E-OI O.OOE+OO 1.59E-01 

B-122 
CLASS D AMAD = 1 MICRON STABLE HAFNIUM: 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2. 56E-Ol 2.26E-Ol 3.03E-04 1.56E-Ol 6. 38E-Ol 

2.00E-Ol 2. 79E-Ol 2.01E-Ol 2. 96E-07 1. 56E-Ol 6.36E-Ol 

3.00E-Ol 2. 99E-Ol 1. 79E-Ol O.OOE+OO 1.55E-Ol 6. 33E-Ol 

4.00E-ol 3. 16E-Ol 1.60E-Ol O.OOE+OO 1. 52E-Ol 6. 28E-Ol 

5.00E-Ol 3. 32E-Ol 1. 43E-Ol O.OOE+OO 1.48E-Ol 6. 22E-Ol 

6.00E-Ol 3. 45E-Ol 1. 27E-Ol O.OOE+OO 1. 42E-Ol 6. 15E-Ol 

7.00E-Ol 3. 58E-Ol 1. 13E-01 O.OOE+OO 1. 36E-Ol 6.06E-Ol 

8.00E-Ol 3. 68E-Ol 1.01E-Ol O.OOE+OO 1. 29E-Ol 5. 98E-Ol 

9.00E-Ol 3.77E-Ol 8.96E-02 O.OOE+OO 1.22E-Ol 5.89,&-01 

1.00E+00 3. 85E-Ol 7. 97E-02 O.OOE+OO 1. 15E-Ol 5.80E-Ol 

2.00E+00 4.22E-01 2. 42E-02 O.OOE+OO 5.24E-02 4.98E-Ol 

3.00E+00 4.20E-Ol 7. 13E-03 O.OOE+OO 2.09E-02 4. 48E-Ol 

4.00E+00 4.08E-Ol 2.05E-03 O.OOE+OO 7. 94E-03 4. 18E-Ol 

5.00E+00 3. 93E-Ol 5. 81E-04 O.OOE+OO 2. 96E-03 3. 97E-Ol 

6.00E+00 3. 79E-Ol 1. 62E-04 O.OOE+OO l.lOE-03 3.80E-Ol 

7.00E+00 3. 66E-ol 4. 47E-05 O.OOE+OO 4.04E-04 3. 67E-Ol 

8.00E+00 3. 54E-Ol 1.22E-05 O.OOE+OO 1.49E-04 3. 54E-Ol 

9.00E+00 3. 43E-Ol 3. 32E-06 O.OOE+OO 5. 48E-05 3. 44E-Ol 

1.00E+Ol 3. 34E-Ol 8.96E-07 O.OOE+OO 2.02E-05 3. 34E-Ol 

2.00E+Ol 2. 75E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 75E-Ol 

3.00E+Ol 2. 53E-Ol O.OOE+OO O.OOE+OO· O.OOE+OO 2. 53E-Ol 

4.00E+Ol 2. 44E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 44E-Ol 

5.00E+Ol 2. 41E-01 O.OOE+OO O.OOE+OO O.OOE+OO 2,,41E-Ol 

6.00E+Ol 2.40E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.40E-Ol 

7.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+09 2.39E-Ol 

8.00E+Ol 2. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 39E-Ol 

9.00E+Ol 2. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.38E-Ol 

1.00E+02 2. 38E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 38E-Ol 

2.00E+02 2. 36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 36E-Ol 

3.00E+02 2. 34E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 34E-Ol 

4.00E+02 2. 32E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 32E-Ol 

5.00E+02 2.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.30E-Ol 

6.00E+02 2. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 28E-Ol 

7.00E+02 2. 26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 26E-Ol 

8.00E+02 2.24E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 24E-Ol .( . 9.00E+02 2. 22E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 22E-Ol 

1.00E+03 2.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.20E-Ol 

2.00E+03 2.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.02E-Ol 

4.00E+03 1.70E-Ol O.OOE+OO O.OOE<+OO O.OOE+OO 1.70E-Ol 

8.00E+03 1.20E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.20E-Ol 

1.00E+04 1.01E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.01E-Ol 

2.00E+04 4. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 25E-02 

B-I23 
CLASS D AHAD = 1 MICRON STABLE HAFNIUM 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 1.04E-03 6.07E-05 

2.00E-Ol 2. 36E-03 7. 42E-04 

3.00E-Ol 3. 77E-03 2.64E-03 

4.00E-Ol 5. 28E-03 5. 93E-03 

5.00E-Ol 6. 85E-03 1.05E-02 

6.00E-Ol 8. 49E-03 1. 61E-02 

7.00E-Ol 1.02E-02 . 2. 25E-02 

8.00E-Ol 1. 19E-02 2. 94E-02 

9.00E-Ol 1. 37E-02 3.66E-02 

1.00E+OO 1.55E-02 1.55E-02 4.40E-02 4.40E-02 

2.00E+OO I.90E-02 3. 46E-02 6.23E-02 1.06E-Ol 

3.00E+OO 1. 88E-02 5.33E-02 3. 15E-02 1. 38E-Ol 

4.00E+OO 1.75E-02 7.08E-02 1.29E-02 1.51E-Ol 

5.00E+OO 1. 59E-02 8.67E-02 4. 98E-03 1. 56E-Ol 

6.00E+OO 1. 45E-02 1.0IE-Ol 1. 87E-03 1. 58E-Ol 

7.00E+OO 1. 31E-02 1. 14E-Ol 6.92E-04 1. 58E-Ol 

8.00E+OO 1. 19E-02 1. 26E-Ol 2.55E-04 1.59E-Ol 

9.00E+OO 1.08E-02 1.37E-Ol 9.40E-05 1. 59E-Ol 

1.00E+Ol 9.77E-03 1.47E-Ol 3. 46E-05 1. 59E-Ol 

2.00E+Ol 3. 64E-03 2.06E-Ol O.OOE+OO 1. 59E-Ol 

3.00E+Ol 1.37E-03 2. 28E-Ol O.OOE+OO 1.59E-Ol 

4.00E+Ol 5. 21E-04 2. 36E-Ol O.OOE+OO 1. 59E-Ol 

5.00E+Ol 2.07E-04 2. 39E-Ol O.OOE+OO 1.59E-Ol 

6.00E+Ol 8. 97E-05 2.41E-Ol O.OOE+OO 1. 59E-Ol 

7.00E+Ol 4. 63E-05 2.41E-Ol O.OOE+OO 1.59E-Ol 

8.00E+Ol 3.02E-05 2. 42E-Ol O.OOE+OO· 1. 59E-Ol 

9.00E+Ol 2. 42E-05 2. 42E-Ol O.OOE+OO 1.59E-Ol 

1.00E+02 2. 19E-05 2. 42E-Ol O.OOE+OO 1. 59E-Ol 

2.00E+02 2.05E-05 2. 44E-Ol O.OOE+OO 1. 59E-Ol 

3.00E+02 2.03E-05 2. 46E-Ol O.OOE+OO 1. 59E-Ol 

4.00E+02 2. OlE-OS 2. 48E-Ol O.OOE+OO 1.59E-Ol 

5.00E+02 1. 99E-05 2.50E-Ol O.OOE+OO 1. 59E-Ol 

6.00E+02 .1.98E-05 2. 52E-Ol O.OOE+OO 1.59E-Ol 

7.00E+02 1. 96E-05 2. 54E-Ol O.OOE+OO 1. 59E-Ol 

8.00E+02 1.94E-05 2.56E-0l O.OOE+OO 1. 59E-Ol 

9.00E+02 1. 93E-05 2. 58E-Ol O.OOE+OO 1. 59E-Ol 

I.OOE+03 1.91E-05 2.60E-Ol O.OOE+OO 1. 59E-Ol 

2.00E+03 1. 75E-05 2. 78E-Ol O.OOE+OO 1. 59E-Ol 

4.00E+03 1.47E-05 3. llE-OI O.OOE+OO 1.59E-Ol 

8.00E+03 1.04E-05 3.60E-Ol O.OOE+OO 1. 59E-Ol 

1.00E+04 8. 75E-06 3. 79E-Ol O.OOE+OO 1. 59E-Ol 

2.00E+04 3. 68E-06 4. 38E-Ol O.OOE+OO 1. 59E-Ol 

B-l24 
8-125 
CLASS D AHAJ) - 1 KICilON IlALFLIFE= 4.24B+ol DAYS HAFNIUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 1.04E-03 6.06E-OS 

2.00E-Ol 2.3SE-03 7. 39E-04 

3.00E-Ol 3.76E-03 2. 63E-03 

4.00E-Ol S.24E-03 S.89E-03 

5.00E-Ol 6.80E-03 1.04E;"02 

6.00E-Ol 8.4lE-03 1.S9E-02 

7.00E-Ol 1.OlE-02 2. 22E-02 

8.00E-Ol 1.18E-02 2.90E~02 

9.00E-Ol 1.3SE-02 3.6lE-02 

1.OOE+OO 1.S3E-02 1.S3E-02 4. 33E-02 4. 33E-02 

2.00E+OO 1. 84E-02 3. 34E-02 6.03E-02 1.03E-Ol 

3.00E+OO 1. 79E-02 S.08E-02 3.00E-02 1.3lE-Ol 

4.00E+OO 1. 63E-02 6. 63E-02 1.2lE-02 1.4lE-Ol 

S.OOE+OO 1. 47E-02 7. 99E-02 4.S9E-03 1. 43E-Ol 

6.00E+OO 1.3lE-02 9.l7E-02 1.69E-03 1.43E-Ol 

7.00E+OO 1.17E-02 1.02E-Ol 6.l7E-04 1.4lE-Ol 

8.00E+OO 1.04E-02 1.11E-0l 2. 24E-04 1.39E-Ol 

9.00E+OO 9.3lE-03 1.18E-Ol 8.l2E-OS 1. 37E-Ol 

1.OOE+Ol 8. 29E-03 1.2SE-Ol 2.94E-OS 1.3SE-Ol 

2.00E+Ol 2. 63E-03 1. 48E-Ol O.OOE+OO 1.14E-Ol 

3.00E+Ol 8. 37E-04 1.40E-Ol O.OOE+OO 9. 72E-02 

4.00E+Ol 2.71E-04 1. 23E-Ol O.OOE+OO 8.2SE-02 

S.OOE+Ol 9.l2E-OS 1.06E-Ol O.OOE+OO 7.0lE-02 

6.00E+Ol 3. 37E-OS 9.03E-02 O.OOE+OO S.9SE-02 

7.00E+Ol 1. 48E-OS 7.69E-02 O.OOE+OO S.OSE-02 

8.00E+Ol 8.l7E-06 6.S4E-02 O.OOE+OO 4. 29E-02 

9.00E+Ol S.SSE-06 S.S6E-02 O.OOE+OO 3.64E-02 

1.OOE+02 4. 28E-06 4. 72E-02 O.OOE+OO 3.09E-02 

2.00E+02 7. 78E-07 9. 29E-03 O.OOE+OO 6.03E-03 

3.00E+02 1.SOE-07 1. 83E-03 O.OOE+OO 1.18E-03 

4.00E+02 2.91E-08 3.S9E-04 O.OOE+OO 2.29E-04 

I, : __ ~ 

~ , . 

B-126 
CLASS D AHA» = 1 KICRON S'lABLE TOBGSTEB 184 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.21E-Ol 2.26E-Ol. 3.03E-04 1.41E-Ol S.SSE-Ol 

2.00E-Ol 2.07E-Ol 2.01E-Ol 2. 96E-07 1. 24E-Ol S.32E-Ol 

3.00E-Ol 1.S6E-Ol 1.79E-Ol O.OOE+OO 1.15E-0l 4.80E-Ol 

4.00E-Ol 1.6SE-Ol 1.60E-Ol O.OOE+OO 1.OSE-Ol 4. 34E-ol 

S.OOE~Ol 1. 46E-Ol 1. 43E-Ol O.OOE+OO 1.03E-Ol 3.92E-0l 

6.00E-Ol 1. 29E-Ol 1.27E-Ol O.OOE+OO 9. 86E-02 3.SSE-Ol 

7.00E-Ol 1.lSE-Ol 1.13E-Ol O.OOE+OO 9. 36E-02 3. 22E-Ol 

S.OOE-Ol 1.03E-Ol 1.OlE-Ol O.OOE+OO S.S4E-02 2. 92E-Ol 

9.00E-0l 9.2SE-02 S.96B-02 O.OOE+OO S.32E-02 2.6SE-Ol 

1.OOE+OO S.37E-02 7. 97E-02 O.OOE+OO 7. 79E-02 2.41E-Ol 

2.00E+OO 4.0SE-02 2. 42E-02 O.OOE+OO 3. SOE-02 9.9SE-02 

3.00E+OO 2. 77E-02 7.13E-03 O.OOE+OO 1. 39E-02 4.S7E-02 

4.00E+OO 2.3lE-02 2.0SE-03 O.OOE+OO S.26E-03 3.04E-02 

S.OOE+OO 2.11E-02 S.81E-04 O.OOE+OO 1. 96E-03 2. 36E-02 

6.00E+OO 1. 99E-02 1.62E-04 O.OOE+OO. 7.2SE-04 2.0SE-02 

7.00E+OO 1.91E-02 4.47E-OS O.OOE+OO 2. 67E-04 1. 94E-02 

8.00E+OO 1. 84E-02 1.22E-OS O.OOE+OO 9.8SE-OS 1.8SE-02 

9.00E+OO 1. 78E-02 3. 32E-06 O.OOE+OO 3. 63E-OS 1.78E-02 

1.OOE+Ol 1.73E-02 S.96E-07 O.OOE+OO 1. 33E-OS 1. 73E-02 

2.00E+Ol 1.4SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.4SE-02 

3.00E+Ol 1.3SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.3SE-02 

4.00E+Ol 1.30E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-02 

S.OOE+Ol 1. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.27E-02 

6.00E+Ol 1. 24E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-02 

7.00E+Ol 1.21E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.21E-02 

8.00E+Ol 1.18E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.lSE-02 

9.00E+Ol 1.lSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.lSE-02 

1.OOE+02 1.13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.13E-02 

2.00E+02 9. 37E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9. 37E-03 

3.00E+02 S.l7E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.17E-03 

4.00E+02 7. 33E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7. 33E-03 

S.OOE+02 6.70E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.70E-03 

6.00E+02 6.1SE-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.1SE-03 

7.00E+02 S.73E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.73E-03 

8.00E+02 S.33E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.33E-03 

9.00E+02 4. 96E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 96E-03 ... 

1.OOE+03 4. 63E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-03 

2.00E+03 2.31E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.31E-03 

4.00E+03 S.78E-04 O.OOE+OO O.OOE+OO O.OOE+OO S.78E-04 

8.00E+03 3.61E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.61E-OS 

1.OOE+04 9.05E-06 O.OOE+OO O.OOE+OO O.OOE+OO 9.05E-06 

2.00E+04 2.61E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2.61E-08 

B-127 
CLASS D AHAD = 1 MICRON' STABLE TUNGSTEN' 184 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 5.08E-02 5.80E-05 

2.00E-Ol 1.06E-Ol 6. 78E-04 

3.00E-Ol 1.56E-Ol 2. 32E-03 

4.00E-Ol 2.00E-Ol 5.03E-03 

5.00E-Ol 2. 38E-Ol 8.66E-03 

6.00E-Ol 2.71E-Ol 1.30E-02 

7.00E-01 3.00E-Ol 1.78E-02 

8.00E-Ol 3. 24E-Ol 2. 28E-02 

9.00E-Ol 3.46E-Ol 2.81E-02 

1.00E+00 3. 64E-Ol 3. 64E-Ol 3. 34E-02 3. 34E-02 

2.00E+00 9. 86E-02 4. 63E-Ol 4. 29E-02 7. 63E-02 

3.00E+00 2. 99E-02 4. 93E-Ol 2. l1E-02 9. 74E-02 

4.00E+00 9. 69E-03 5.03E-Ol 8.61E-03 1.06E-Ol 

5.00E+00 3.50E-03 5.06E-Ol 3.30E-03 1.09E-Ol 

6.00E+00 1. 59E-03 5.08E-Ol 1. 24E-03 1. 11E-Ol 

7.00E+00 9. 61E-04 5.09E-Ol 4. 58E-04 1. 11E-Ol 

8.00E+00 7.20E-04 5.09E-Ol 1.69E-04 1.11E-Ol 

9.00E+00 5. 98E-04 5.10E-Ol 6. 23E-05 1. 11E-Ol 

1.00E+Ol 5. 16E-04 5. 11E-01 2.29E-05 1. 11E-Ol 

2.00E+Ol 1. 56E-04 5. 13E-Ol O.OOE+OO 1. 11E-Ol 

3.00E+Ol 6. 56E-05 5. 14E-Ol O.OOE+OO 1. 11E-Ol 

4.00E+Ol 4. 15E-05 5. 15E-Ol O.OOE+OO 1. 11E-Ol 

5.00E+Ol 3.41E-05 5. 15E-Ol O.OOE+oo 1. 11E-Ol 

6.00E+Ol 3.09E-05 5. 15E-Ol O.OOE+OO· 1. 11E-Ol 

7.00E+Ol 2. 89E-05 5. 16E-Ol O.OOE+oo 1. 11E-Ol 

8.00E+Ol 2. 72E-05 5. 16E-Ol O.OOE+OO 1. 11E-Ol 

9.00E+Ol 2. 58E-05 5. 16E-01 O.OOE+OO 1. 11E-Ol 

1.00E+02 2. 44E-05 5~17E-Ol O.OOE+OO 1. 11E-Ol 

2.00E+02 1.48E-05 5. 18E-Ol O.OOE+oo 1.11E-Ol 

3.00E+02 9.81E-06 5.20E-Ol O.OOE+OO 1. 11E-Ol 

4.00E+02 7. 16E-06 5.20E-Ol O.OOE+oo 1. 11E-Ol 

5.00E+02 5. 68E-06 5.21E-Ol O.OOE+OO 1. 11E-Ol 

6.00E+02 4.80E-06 5. 22E-Ol O.OOE+oo 1. 11E-Ol 

7.00E+02 4. 23E-06 5.22E-Ol O.OOE+OO 1. 11E-Ol 

8.00E+02 3. 82E-06 5.23E-Ol O.OOE+oo 1. 11E-Ol 

9.00E+02 3. 51E-06 5.23E-Ol O.OOE+OO 1. 11E-Ol 

1.00E+03 3. 24E-06 5. 23E-Ol O.OOE+oo 1.11E-Ol 

2.00E+03 1.60E-06 5.26E-Ol O.OOE+OO 1. 11E-Ol 

4.00E+03 4.06E-07 5.27E-01 O.OOE+oo 1.11E-Ol 

8.00E+03 3.60E-08 5.28E-Ol O.OOE+OO 1. 11E-Ol 

1.00E+04 1.99E-08 5. 28E-Ol O.OOE+oo 1. 11E-Ol 

2.00E+04 2. 73E-08 5. 28E-Ol O.OOE+OO 1. 11E-Ol 

B-128 
CLASS D MAD - 1 KICItOR IIALFLIPB- 3.78£+00 DAYS lDIBHIUH 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 23E-0l 2. 22E-Ol 2.97E-04 7. 28E-02 6.lSE-01 

2.00E-Ol 3. 63E-Ol 1. 94E-Ol 2.SSE-07 3.SSE-02 S.93E-Ol 

3.00E-Ol 3.67E-Ol 1.70E-01 O.OOE+OO 2.97E-02 S.67E-Ol 

4.00E-Ol 3.6SE-.ol 1. 49E-Ol O.OOE+OO 2.77E-02 S.4lE-01 

S.OOE-Ol 3.60E-Ol 1.30E-Ol O.OOE+OO 2.60E-02 S.17E-01 

6.00E-Ol 3.S4E-Ol 1. 14E-Ol O.OOE+OO 2. 43E-Q2 4. 92E-Ol 

7.00E-Ol 3.47E-Ol 9.9SE-02 O.OOE+OO 2.2SE-02 4.69E-Ol 

S.OOE-Ol 3. 39E-Ol S.69E-02 O.OOE+OO 2.0SE-02 4. 46E-Ol 

9.00E-Ol 3.29E-Ol 7.60E-02 O.OOE+OO 1.9lE-02 4. 24E-0l 

1.00E+00 3.20E-Ol 6. 63E-02 O.OOE+OO 1.7SE-02 4.04E-Ol 

2.00E+00 2.lSE-0l 1.6SE-02 O.OOE+OO 6. 41E-03 2. 41E-0l 

3.00E+00 1.3SE-01 4.llE-03 O.OOE+OO 2.l0E-03 1. 44E-Ol 

4.00E+00 S.6SE-02 9.S6E-04 O.OOE+OO 6.6lE-04 S.S2E-02 

S.OOE+OO S.47E-02 2. 32E-04 O.OOE+OO 2.0SE-Q4 S.S2E-02 

6.00E+00 3.S3E-02 S.39E-OS O.OOE+OO 6.3lE-OS 3.S4E-02 

7.00E+00 2. 33E-02 1. 24E-OS O.OOE+OO 1. 94E-OS 2. 33E-02 

S.OOE+OO I.S7E-02 2.S2E-06 O.OOE+OO S.93E-06 I.SBE-02 

9.00E+00 1.09E-02 6.3SE-07 O.OOE+OO I.S2E-06 1.09E-02 

1.00E+Ol 7.70E""03 1. 43E-07 O.OOE+OO S.S7E-07 7.70E-03 

2.00E+Ol 4. BOE-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. BOE-04 

3.00E+Ol 4.B7E-OS O.OOE+OO O.OOE+OO O.OOE+OO 4.S7E-OS 

4.00E+Ol S.SlE-06 O.OOE+OO O.OOE+OO O.OOE+OO S.SlE-06 

S.OOE+Ol 6.3SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 6.3BE-07 

6.00E+Ol 7. 43E-OB O.OOE+OO O.OOE+OO O.OOE+OO 7. 43E-OB 

B-129 
CLASS D AHAD ... 1 MICltOH BALPLIFE- 3.78£+00 DAYS RllE.HIUM 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 9.SSE-03 4.09E-OS 

2.00E-Ql 2. 32E-02 3. 66E-04 

3.00E-Ol 3.70E-02 1.04E-03 

4.00E-Ol S.06E-02 1. 97E-03 

S.OOE-OI 6.3SE-02 3.07E-03 

6.00E-Ol 7.60E-02 4. 26E-03 

7.00E-Ql B.7BE-02 S.48E-03 

B.OOE-Ol 9.90E-02 6. 69E-03 

9.00E-0l 1. IOE-Ol 7. B6E-03 

I.OOE+OO I.I9E-OI I.I9E-OI B.9BE-03 B.9BE-03 

2.00E+OO B.69E-02 1. B6E-OI B.16E-03 1. S6E-02 

3.00E+OO S.30E-02 2.0BE-OI 3. 23E-03 1. 62E-02 

4.00E+OO 3.09E-02 2.04E-0l 1.09E-03 I.46E-02 

S.OOE+OO 1. 79E-02 I.BBE-OI 3. 46E-04 1.2SE-02 

6.00E+OO 1.04E-02 I.67E-Ol 1.07E-04 I.OSE-02 

7.00E+OO 6.11E-03 I.4SE-Ol 3. 31E-OS B.79E-03 

B.OOE+OO 3.6SE-03 1.24E-Ol 1.02E-OS 7.33E-03 

9.00E+OO 2. 22E-03 I.06E-OI 3. 12E-06 6.lOE-03 

1.00E+OI 1.37E-03 B.94E-02 9. S6E-07 S.OBE-03 

2.00E+Ol 2. 99E-OS I.S0E-02 O.OOE+OO B.12E-04 

3.00E+Ol 1.B9E-06 2. 43E-03 O.OOE+OO I.30E-04 

4.00E+Ol 1. 84E-07 3.91E-04 O.OOE+OO 2.07E-OS 

S.OOE+Ol 2.06E-08 6. 27E-OS O.OOE+OO 3. 32E-06 

B-130 
CLASS D .AHAD = 1 KICR.OR STABLE OSKIOK 190 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 47E-Ol 2.26E-Ol 3.03E-04 1. 56E-Ol 6. 28E-Ol 

2.00E-Ol 2.60E-Ol 2.0lE-0l 2. 96E-07 1. 55E-Ol 6.17E-Ol 

3.00E-Ol 2. 72E-Or 1.79E-0l O.OOE+OO 1.54E-Ol 6.05E-Ol 

4.00E-Ol 2. 83E-Ol 1.60E-Ol O.OOE+OO 1.5lE-Ol 5. 94E-Ol 

5.00E-Ol 2. 93E-Ol 1.43E-Ol O.OOE+OO 1. 46E-0l 5. 82E-Ol 

6.00E-Ol 3.02E-Ol 1. 27E-Ol O.OOE+OO 1.41E-Ol 5.70E-Ol 

7.00E-Ol 3.lOE-0l 1.BE-Ol O.OOE+OO 1.35E-Ol 5.57E-Ol 

8.00E-Ol 3.l7E-Ol 1.OlE-Ol O.OOE+OO 1. 28E-Ol 5. 45E-Ol 

9.00E-Ol 3. 23E-Ol 8.96E-02 O.OOE+OO 1.2lE-Ol 5.33E-Ol 

1.OOE+OO 3. 29E-Ol 7. 97E-02 O.OOE+OO l.l4E-Ol 5. 22E-Ol 

2.00E+OO 3. 58E-0l 2. 42E-02 O.OOE+OO 5.l9E-02 4. 34E-Ol 

3.00E+OO 3. 63E-Ol 7.l3E-03 O.OOE+OO 2.07E-02 3.9lE-ol 

4.00E+OO 3.60E-Ol 2.05E-03 O.OOE+OO 7. 86E-03 3.70E-Ol 

5.00E+OO 3. 55E-Ol 5.8lE-04 O.OOE+OO 2. 93E-03 3. 59E-Ol 

6.00E+OO 3.50E-Ol l.62E-04 O.OOE+OO 1.09E-03 3.5lE-Ol 

7.00E+OO 3. 45E-Ol 4. 47E-05 O.OOE+OO 4.00E-04 3. 46E-Ol 

8.00E+OO 3.4lE-0l 1. 22E-05 O.OOE+OO 1. 47E-04 3. 41E-:-01 

9.00E+OO 3. 36E-01 3. 32E-06 O.OOE+OO 5. 42E-05 3. 36E-Ol 

1.OOE+Ol 3. 32E-0l 8.96E-07 O.OOE+OO 2.00E-05 3. 32E-Ol 

2.00E+Ol 3.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-Ol 

3.00E+01 2. 84E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 84E-Ol 

4.00E+Ol 2.71E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.71E-Ol 

5.00E+Ol 2.6lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.6lE-Ol 

6.00E+Ol 2.5lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.5lE-Ol 

7.00E+Ol 2. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-Ol 

8.00E+Ol 2. 34E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 34E-Ol 

9.00E+Ol 2. 26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 26E-ol 

l.OOE+02 2. 18E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2. 18E-Ol 

2.00E+02 1. 54E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 54E-Ol 

3.00E+02 l.09E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-Ol 

4.00E+02 7.7.2E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.72E-02 

5.00E+02 5. 46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 46E-02 

6.00E+02 3. 86E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 86E-02 

7.00E+02 2. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 73E-02 

8.00E+02 1.93E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.93E-02 

9.00E+02 1. 37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 37E-02 . ".' 1.OOE+03 9.66E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.66E-03 

2.00E+03 3.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-04 

3.00E+03 9. 44E-06 O.OOE+OO O.OOE+OO O.OOE+OO 9. 44E-06 

4.00E+03 2. 93E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 93E-07 

B-131 
CLASS D AHA» - 1 MICRON STABLE OSMIUM 190 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.07E-02 6.07E-05 

2.00E-OI 2.17E-02 7.40E-04 

3.00E-OI 3.13E-02 2.64E-03 

4.00E-OI 3. 97E-02 5.9IE-03 

5.00E-OI 4.71E-02 I.04E-02 

6.00E-OI 5. 36E-02 I.60E-02 

7.00E-OI 5.94E-02 2. 24E-02 

8.00E-0l 6. 46E-02 2. 92E-02 

9.00E-OI 6. 92E-02 3. 64E-02 

I.OOE+OO 7. 34E-02 7. 34E-02 4. 37E-02 4. 37E-02 

2.00E+OO 2.59E-02 9. 93E-02 6.18E-02 I.06E-OI 

3.00E+OO 1. 24E-02 I.I2E-OI 3.I2E-02 I.37E-OI 

4.00E+OO 7.93E-03 I.20E-0l 1. 28E-02 I.50E-OI 

5.00E+OO 6. 28E-03 1. 26E-OI 4. 93E-03 1. 54E-OI 

6.00E+OO 5.52E-03 I.3IE-OI 1. 85E-03 I.56E-OI 

7.00E+OO 5.05E-03 1. 37E-OI 6. 85E-04 1. 57E-OI 

8.00E+OO 4.69E-03 I.41E-OI 2. 53E-04 1. 57E-OI 

9.00E+OO 4. 38E-03 1. 46E-OI 9.3IE-05 1. 57E-OI 

I.OOE+OI 4.09E-03 I.50E-OI 3. 43E-05 I.57E-OI 

2.00E+OI 2. 29E-03 1. 79E-OI O.OOE+OO I.57E-0l 

3.00E+OI I.5IE-03 1. 97E-OI O.OOE+OO 1. 57E-0l 

4.00E+OI I.I6E-03 2.lOE-OI O.OOE+OO I.57E-OI 

5.00E+OI 9. 97E-04 2.2IE-0l O.OOE+OO I.57E-OI 

6.00E+OI 9.11E-04 2.30E-OI O.OOE+OO 1. 57E-OI 

7.00E+OI 8. 58E-04 2. 39E-OI O.OOE+OO 1. 57E-0l 

8.00E+OI 8.19E-04 2. 48E-OI O.OOE+OO 1. 57E-OI 

9.00E+OI 7.88E-04 2. 56E-OI O.OOE+OO 1. 57E-0l 

I.OOE+02 7. 59E-04 2. 63E-OI O.OOE+OO I.57E-OI 

2.00E+02 5:36E-04 3. 27E-OI O.OOE+OO 1. 57E-0l 

3.00E+02 3. 79E-04 3. 73E-OI O.OOE+OO 1. 57E-ol 

4.00E+02 2. 68E-04 4.05E-OI O.OOE+OO I.57E-0l 

5.00E+02 I.90E-04 4.27E-OI O.OOE+OO 1. 57E-OI 

6.00E+02 1. 34E-04 4. 43E-OI O.OOE+OO I.57E-OI 

7.00E+02 9. 48E-05 4. 54E-OI O.OOE+OO 1. 57E-OI 

8.00E+02 6.70E-05 4. 62E-OI O.OOE+OO I.57E-OI 

9.00E+02 4. 74E-05 4. 68E..;.OI O.OOE+OO I.57E-0l 

I.OOE+03 3.35E-05 4.72E-OI O.OOE+OO I.57E-0l 

2.00E+03 I.05E-06 4.8IE-OI O.OOE+OO 1. 57E-Ol 

3.00E+03 3. 36E-08 4. 82E-OI O.OOE+OO I.57E-OI 

B-132 
CLASS D AKAD - 1 KICIlON IlALFLIFE... 7. 40E+OI DAYS IRIDIUII 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 46E-01 2. 26E-Ol 3.02E-04 1.55E-Ol 6. 28E-0l 

2.00E-01 2.60E-Ol 2.01E-Ol 2. 95E-07 1. 55E-01 6. 15E-01 

3.00E-Ol 2.7lE-0l 1. 79E-Ol O.OOE+OO 1. 53E~Ol 6.03E-01 

4.00E-01 2. 82E-Ol 1. 59E-01 O.OOE+OO 1.50E-01 5.9lE-Ol 

S.OOE-01 2. 91E-01 1.42E-Ol O.OOE+OO 1. 46E-Ol 5.79E-0l 

6.00E-01 3.00E-01 1. 26E-01 O.OOE+OO 1.40E-01 5. 66E-Ol 

7.00E-Ol 3.08E-01 1. 12E-01 O.OOE+OO 1.34E-Ol 5.54E-01 

8.00E-01 3. 14E-01 9. 99E-02 O.OOE+OO 1. 27E-01 5.41E-01 

9.00E-0l 3.20E-Ol 8. 88E-02 O.OOE+OO 1.20E-0l 5.29E-01 

1.00E+OO 3. 26E-01 7. 89E-02 O.OOE+OO 1.l2E-Ol 5.l7E-Ol 

2.00E+OO 3.S2E-01 2.38E-02 O.OOE+OO 5.09E-02 4.26E-01 

3.00E+OO 3. 53E-Ol 6. 93E-03 O.OOE+OO 2.01E-02 3.80E-01 

4.00E+OO 3.47E-0l 1.98E-03 O.OOE+OO 7. 57E-03 3. 56E-01 

5.00E+OO 3. 39E-Ol 5.S4E-04 O.OOE+OO 2.80E-03 3. 42E-01 

6.00E+OO 3.31E-Ol 1.53E-04 O.OOE+OO 1.03E-03 3. 32E-01 

7.00E+OO 3. 23E-01 4.l9E-05 O.OOE+OO 3. 75E-04 3. 24E-Ol 

8.00E+OO 3.l6E-Ol 1. 14E-OS O.OOE+OO 1.37E-04 3. 16E-Ol . 

9.00E+OO 3.09E-01 3.05E-06 O.OOE+OO 4. 99E-OS 3.09E-Ol 

1.00E+01 3.02E-01 8.l6E-07 O.OOE+OO 1. 82E-OS 3.02E-Ol 

2.00E+01 2.S1E-01 O.OOE+OO O.OOE+OO O.OOE+OO 2.SlE-Ol 

3.00E+01 2. 15E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2.1SE-01 

4.00E+Ol 1. 87E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.87E-01 

5.00E+01 1.63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.63E-Ol 

6.00E+01 1.43E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 43E-Ol 

7.00E+01 1.26E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 26E-01 

8.00E+Ol 1.HE-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.11E-Ol 

9.00E+01 9. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 73E-02 

1.OOE+02 8. 56E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 56E-02 

2.00E+02 2. 37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 37E-02 

3.00E+02 6. 58E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 58E-03 

4.00E+02 1.82E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 82E-03 

S.OOE+02 5.06E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5.06E-04 

6.00E+02 1.40E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-04 

7.00E+02 3. 89E-05 O.OOE+OO O.OOE+OO O.OOE+OO 3. 89E-OS 

8.00E+02 1.08E-05 O.OOE+OO O.OOE+OO O.OOE+OO 1.08E-05 

. .' . 9.00E+02 2. 99E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 99E-06 

1.OOE+03 8.28E-07 O.OOE+OO O.OOE+OO O.OOE+OO 8. 28E-07 

B-133 
CLASS D AHA» - 1 KICR.ON IlALFLIFE= 7. 40E+Ol DAYS IRIDIUM 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.07E-02 6.06E-05 

2.00E-Ol 2.l7E-02 7. 39E-04 

3.00E-Ol 3.l2E-02 2.63E-03 

4.00E-Ol 3. 96E-02 5. 89E:-03 

5.00E-Ol 4. 69E-02 1.04E-02 

6.00E-Ol 5.33E-02 1. 59E-02 

7.00E-Ol 5.90E-02 2. 22E-02 

8.00E-Ol 6.4lE-02 2. 9 OE";"O 2 

9.00E-Ol 6. 87E-02 3.6lE-02 

1.00E+00 7. 27E-02 7. 27E-02 4. 33E-02 4. 33E-02 

2.00E+00 2. 54E-02 9. 75E-02 6.06E-02 1.04E-01 

3.00E+00 1.2lE-02 1.09E-01 3.03E-02 1.33E-Ol 

4.00E+00 7. 64E-03 1.15E-01 1.24E-02 1.44E-01 

5.00E+00 5. 99E-03 1.20E-01 4.70E-03 1. 47E-0l 

6.00E+00 5. 22E-03 1.24E-01 1.75E-03 1.48E-01 

7.00E+00 4. 73E-03 1.28E-01 6.4lE-04 1.47E-01 

8.00E+00 4. 35E-03 1.3lE-01 2. 35E-04 1.46E-01 

9.00E+00 4.02E-03 1. 34E-Ol 8. 56E-05 1.45E-01 

1.00E+Ol 3. 73E-03 1.36E-01 3.l2E-05 1.43E-01 

2.00E+Ol 1.90E-03 1.49E-01 O.OOE+OO 1.3lE-01 

3.00E+Ol 1.14E-03 1.49E-01 O.OOE+OO 1.19E-01 

4.00E+Ol 7. 98E-04 1.45E-01 O.OOE+OO 1.08E-01 

5.00E+Ol 6. 24E-04 1.38E-Ol O.OOE+OO 9.85E-02 

6.00E+Ol 5.l9E-04 1.31E-01 O.OOE+OO 8. 97E-02 

7.00E+Ol 4.45E-04 1.24E-01 O.OOE+OO 8.l7E-02 

8.00E+Ol 3. 87E-04 1.17E-01 O.OOE+OO 7. 44E-02 

9.00E+Ol 3. 39E-04 1.lOE-0l O.OOE+OO 6. 78E-02 

1.00E+02 2. 98E-04 1.03E-01 O.OOE+OO 6.17E-02 

2.00E+02 8. 24E-05 5.03E-02 O.OOE+OO 2.42E-02 

3.00E+02 2. 28E-05 2. 24E-02 O.OOE+OO 9.48E-03 

4.00E+02 6. 33E-06 9. 55E-03 O.OOE+OO 3.72E-03 

5.00E+02 1. 75E-06 3. 95E-03 O.OOE+OO 1. 46E-03 

6.00E+02 4. 87E-07 1.6lE-03 O.OOE+OO 5.71E-04 

7.00E+02 1.35E-07 6. 47E-04 O.OOE+OO 2. 24E-04 

:, .. :: '".' 8.00E+02 3. 74E-08 2. 58E-04 O.OOE+OO 8.78E-05 ..... 

9.00E+02 1.04E-08 1.02E-04 O.OOE+OO 3. 44E-05 

B-134 
ClASS D AMAD - 1 HICKOM STABLE IR.IDIUH 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 2. 47E-Ol 2. 26E-Ol 3.03E-04 1.S6E-OI 6. 28E-Ol 

2.00E-Ol 2.60E-Ol 2.0lE-Ol 2. 96E-07 1.SSE-Ol 6.l7E-OI 

3.00E-Ol 2. 72E-Ol 1. 79E-Ol O.OOE+OO 1. S4E-Ol 6.0SE-Ol 

4.00E-Dl 2. 83E-Ol 1.60E-Ol O.OOE+OO 1.5lE-OI S.94E-Ol 

S.OOE-Ol 2.93E-Ol 1. 43E-Ol O.OOE+OO 1. 46E-Ol 5. 82E-Ol 

6.00E-Ol 3.02E-Ol 1. 27E-Ol O.OOE+OO 1.4lE-D1 S.70E-Ol 

7.00E-Ol 3.l0E-0l 1. 13E-Ol O.OOE+OO 1.3SE-0l S.S7E-Ol 

S.OOE-Ol 3.l7E-Ol 1.OlE-OI O.OOE+OO 1. 28E-Ol S.4SE-Ol 

9.00E-Ol 3. 23E-Ol 8.96.E-02 O.OOE+OO 1.2lE-Ol 5. 33E-Ol 

1.OOE+OO 3. 29E-Ol 7. 97E-02 O.OOE+OO 1.14E-Ol S.22E-Ol 

2.00E+OO 3.SSE-Ol 2. 42E-02 O.OOE+OO S.19E-02 4.34E-Ol 

3.00E+OO 3. 63E-Ol 7.13E-03 O.OOE+OO 2.07E-02 3.9lE-Ol 

4.00E+OO 3.60E-Ol 2.0SE-03 O.OOE+OO 7.S6E-03 3.70E-Ol 

S.OOE+OO 3.SSE-Ol 5.SlE-04 O.OOE+OO 2. 93E-03 3.S9E-Ol 

6.00E+OO 3.50E-Ol 1. 62E-04 O.OOE+OO 1.09E-03 3.S1E-Ol 

7.00E+OO 3.4SE-Ol 4. 47E-OS O.OOE+OO 4.00E-04 3. 46E-Ol 

8.00E+OO 3.4lE-Ol 1. 22E-OS O.OOE+OO 1.47E-04 3.4IE-Ol 

9.00E+OO 3.36E-Ol 3. 32E-06 O.OOE+OO S.42E-OS 3. 36E-Ol 

1.OOE+Ol 3.32E-Ol 8.96E-07 O.OOE+OO 2.00E-05 3.32E-Ol 

2.00E+Ol 3.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-Ol 

3.00E+Ol 2.S4E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2.S4E-Ol 

4.00E+Ol 2.71E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.71E-Ol 

S.OOE+Ol 2.6lE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.6lE-OI 

6.00E+Ol 2.S1E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 51E-Ol 

7.00E+Ol 2. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.42E-Ol 

S.OOE+Ol 2. 34E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 34E-Ol 

9.00E+Ol 2. 26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.26E-Ol 

1.OOE+02 2.lSE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. ISE-Ol 

2.00E+02 1. 54E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.S4E-Ol 

3.00E+02 1.09E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-Ol 

4.00E+02 7.72E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.72E-02 

S.OOE+02 S.46E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.46E-02 

6.00E+02 3.S6E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.S6E-02 

7.00E+02 2. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 73E-02 

S.OOE+02 1. 93E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 93E-02 

9.00E+02 1. 37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.37E-02 .. '., 1.OOE+03 9. 66E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9. 66E-03 

2.00E+03 3.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.02E-04 

3.00E+03 9. 44E-06 O.OOE+OO O.OOE+OO O.OOE+OO 9. 44E-06 

4.00E+03 2. 93E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 93E-07 

B-135 
CLASS D AMAD = 1 MICRON STABLE mIDIUK 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.07E-02 6.07E-05 

2.00E-Ol 2. 17E-02 7.40E-04 

3.00E-Ol 3. 13E-02 2. 64E-03 

4.00E-Ol ---./ 3. 97E-02 5.91E-03 

5.00E-Ol 4. 71E-02 1.04E-02 

6.00E-ol 5. 36E-02 1.60E-02 

7.00E-01 5. 94E-02 2.24E-02 

8.00E-Ol 6.46E-02 2. 92E-02 

9.00E-Ol 6. 92E-02 3.64E-02 

1.00E+00 7. 34E-02 7.34E-02 4. 37E-02 4. 37E-02 

2.00E+00 2. 59E-02 9. 93E-02 6. 18E-02 1.06E-Ol 

3.00E+00 1. 24E-02 1. 12E-Ol 3. 12E-02 1.37E-Ol 

4.00E+00 7. 93E-03 1.20E-Ol 1. 28E-02 1.50E-Ol 

5.00E+00 6. 28E-03 1.26E-Ol 4. 93E-03 1. 54E-Ol 

6.00E+00 5. 52E-03 1. 31E-Ol 1. 85E-03 1.56E-Ol 

7.00E+00 5.05E-03 1.37E-Ol 6. 85E-04 1. 57E-Ol 

8.00E+00 4 .• 69E-03 1.41E-Ol 2.53E-04 1.57E-01 

9.00E+OO 4. 38E-03 1.46E-Ol 9.31E-05 1. 57E-Ol 

1.00E+Ol 4.09E-03 1.50E-Ol 3. 43E-05 1.57E-Ol 

2.00E+Ol 2. 29E-03 1. 79E-Ol O.OOE+OO 1.57E-Ol 

3.00E+Ol 1.51E-03 1.97E-Ol O.OOE+OO 1. 57E-Ol 

4.00E+Ol 1. 16E-03 2.10E-01 O.OOE+OO 1. 57E-Ol 

5.00E+Ol 9. 97E-04 2.21E-Ol O.OOE+oo 1.57E-Ol 

6.00E+Ol 9. l1E-04 2.30E-Ol O.OOE+OO 1. 57E-Ol 

7.00E+Ol 8. 58E-04 2. 39E-Ol O.OOE+oo 1. 57E-Ol 

8.00E+Ol 8. 19E-04 2. 48E-Ol O.OOE+OO 1. 57E-01 

9.00E+01 7.88E-04 2. 56E-Ol O.OOE+oo 1.57E-Ol 

1.00E+02 7. 59E-04 2. 63E-Ol O.OOE+OO 1. 57E-Ol 

2.00E+02 5. 36E-04 3.27E-Ol O.OOE+oo 1. 57E-Ol 

3. o OE+O 2 3. 79E-04 3. 73E-Ol O.OOE+OO 1. 57E-Ol 

4.00E+02 2. 68E-04 4.05E-Ol O.OOE+oo 1.57E-Ol 

5.00E+02 1.90E-04 4. 27E-Ol O.OOE+OO 1. 57E-Ol 

6.00E+02 1. 34E-04 4.43E-Ol O.OOE+OO 1. 57E-Ol 

7.00E+02 9. 48E-05 4. 54E-Ol O.OOE+OO 1. 57E-Ol 

8.00E+02 6.70E-05 4. 62E-Ol O.OOE+oo 1.57E-Ol \ 1·-

9.00E+02 4. 74E-05 4. 68E-Ol O.OOE+OO 1. 57E-01 

1.00E+03 3. 35E-05 4. 72E-Ol O.OOE+oo 1.57E-01 

2.00E+03 1.05E-06 4. 81E-Ol O.OOE+OO 1.57E-Ol 

3.00E+03 3. 36E-08 4. 82E-Ol O.OOE+oo 1.57E-Ol 

B-136 
CLASS D AHAD = 1 MICltOR STABLE PLATINUM. 195 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

l.OOE-Oi 2.46E-Ol 2.26E:-Ol 3.03E-04 1. S6E-Ol 6.27E-Ol 

2.00E-Ol 2.S8E-Ol 2.0lE-Ol 2. 96E-07 1.SSE-Ol 6.14E-Ol 

3.00E-Ol 2. 68E-Ol 1.79E-0i O.OOE+OO 1. 54E-Ol 6.0lE-Ol 

4.00E-Ol 2. 77E-Ol l.60E-Ol O.OOE+OO 1.51E-Ol S.88E-Ol 

S.OOE-Ol 2.86E-Ol 1. 43E-Ol O.OOE+OO 1.46E-Ol 5. 75E-Ol 

6.00E-Ol 2. 93E-Ol l.27E-Ol O.OOE+OO 1.41E-Ol 5.61E-Ol 

7.00E-Ol 2. 99E-Ol 1.l3E-Ol O.OOE+OO 1. 35E-0l 5.47E-Ol 

8.00E-Ol 3.0SE-Ol 1.OlE-OI O.OOE+OO 1. 28E-OI 5. 33E-Ol 

9.00E-Ol 3.09E-0l 8. 96E-02 O.OOE+OO 1.2IE-OI 5.20E-OI 

I.OOE+OO 3.13E-OI 7.97E-02 O.OOE+OO 1.14E-OI S.06E-OI 

2.00E+OO 3. 23E-Ol 2.42E-02 O.OOE+OO 5. 19E-02 3. 99E-OI 

3.00E+OO 3.08E-Ol 7.13E-03 O.OOE+OO 2.07E-Q2 3. 36E-Ol 

4.00E+OO 2. 88E-OI 2.05E-03 O.OOE+OO 7.86E-03 2.97E-OI 

5.00E+OO 2. 66E-Ol S.8IE-04 O.OOE+OO 2. 93E-03 2.70E-Ol 

6.00E+OO 2.46E-OI 1.62E-04 O.OOE+OO I.09E-03 2.47E-OI 

7.00E+OO 2. 27E-OI 4.47E-OS O.OOE+OO 4.00E-04 2.27E-OI 

8.00E+OO 2.10E-0l 1. 22E-OS O.OOE+OO 1.47E-04 2.lOE-0i 

9.00E+OO 1.94E-OI 3. 32E-06 O.OOE+OO S.42E-05 1.94E-OI 

1.OOE+OI I.79E-OI 8.96E-07 O.OOE+OO 2.00E-OS 1.79E-Ol 

2.00E+OI 8.S5E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.SSE-02 

3.00E+OI 4.S8E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.S8E-02 

4.00E+OI 2.87E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 87E-02 

S.OOE+Ol 2.12E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.12E-02 

6.00E+OI I.78E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.78E-02 

7.00E+OI 1.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-02 

8.00E+OI 1.50E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.SOE-02 

9.00E+OI I.43E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.43E-02 

I.OOE+02 I.37E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 37E-02 

2.00E+02 9. 65E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.6SE-03 

3.00E+02 6. 82E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 82E-03 

4.00E+02 4. 83E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 83E-03 

5.00E+02 3.4IE-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.4IE-03 

6.00E+02 2.4IE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.4IE-03 

7.00E+02 I.71E-03 O.OOE+OO O.OOE+OO O.OOE+OO I.71E-03 

8.00E+02 I.21E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.2lE-03 

9.00E+02 8.S3E-04 O.OOE+OO O.OOE+OO O.OOE+OO 8.S3E-04 . " . 

I.boE+03 6.04E-04 O.OOE+OO ,," , 

, I 

< 

",' O.OOE+OO O.OOE+OO 6.04E-04 

2.00E+03 1.89E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1. 89E-OS 

3.00E+03 5. 88E-07 O.OOE+OO O.OOE+OO O.OOE+OO 5. 88E-07 

4.00E+03 I.60E-08 O.OOE+OO O.OOE+OO O.OOE+OO I.60E-08 

B-137 
CI.ASS D AH.AD =- 1 HICKON STABLE PLATlNUH 195 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1. 18E-02 6.07E-05 

2.00E-01 2.41E-02 7.40E-04 

3.00E-01 3. 51E-02 2. 64E-03 

4.00E-01 4.50E-02 5. 91E-03 

5.00E-Ol 5.40E-02 1.04E-02 

6.00E-01 6.22E-02 1.60E-02 

7.00E-01 6.97E-02 2. 24E-02 

8.00E-01 7. 67E-02 2. 92E-02 

9.00E-01 8. 31E-Q2 3. 64E-02 

1.00E+OO 8. 92E-02 8. 92E-02 4. 37E-02 4. 37E-02 

2.00E+OO 4. 53E-02 1. 34E-01 6. 18E-02 1.06E-01 

3.00E+OO 3. 17E-02 1. 66E-01 3. 12E-02 1. 37E-01 

4.00E+OO 2.60E-02 1. 92E-01 1.28E-02 1.50E-Ol 

5.00E+OO 2. 29E-02 2. 15E-01 4. 93E-03 1.54E-01 

6.00E+OO 2.07E-02 2. 36E-01 1.85E-03 1.56E-01 

7.00E+OO 1. 89E-02 2. 55E-01 6. 85E-04 1. 57E-01 

8.00E+OO 1. 73E-02 2.72E-01 2.53E-04 1.57E-01 

9.00E+OO 1. 59E-02 2. 88E-01 9.31E-05 1. 57E-01 

1.00E+01 1. 46E-02 3.03E-01 3.43E-05 1.57E-01 

2.00E+01 6. 17E-03 3. 96E-01 O.OOE+OO 1.57E-01 

3.00E+01 2. 63E-03 4.36E-01 O.OOE+OO 1.57E-Ol 

4.00E+01 1. 14E-03 4. 53E-01 O.OOE+OO 1. 57E-01 

5.00E+01 5.11E-04 4.60E-01 O.OOE+OO 1. 57E-01 

6.00E+01 2. 45E-04 4. 64E-01 O.OOE+OO 1.57E-01 . 

7.00E+01 1. 33E-04 4. 66E-01 O.OOE+OO 1.57E-01 

8.00E+01 8. 45E-05 4. 67E-01 O.OOE+OO 1. 57E-01 

9.00E+01 6. 32E-05 4. 67E-01 O.OOE+OO 1.57E-01 

1.00E+02 5. 33E-05 4. 68E-01 O.OOE+OO 1. 57E-01 

2.00E+02 3. 35E-05 4. 72E-01 O.OOE+OO 1. 57E-01 

3.00E+02 2. 37E-05 4. 75E-01 O.OOE+OO 1. 57E-01 

4.00E+02 1. 68E-05 4. 77E-01 O.OOE+OO 1.57E-01 

5.00E+02 1. 18E-05 4. 78E-01 O.OOE+OO 1. 57E-01 

6.00E+02 8. 38E-06 4. 79E-01 O.OOE+OO 1. 57E-01 

7.00E+02 5. 92E-06 4.80E-01 O.OOE+OO 1.57E-01 I 8.00E+02 4. 19E-06 4.81E-01 O.OOE+OO 1.57E-01 

9.00E+02 2. 96E-06 4.81E-01 O.OOE+OO 1. 57E-01 

1.00E+03 2.10E-06 4.81E-01 O.OOE+OO 1. 57E-01 

2.00E+03 6.60E-08 4. 82E-01 O .. OOE+OO 1. 57E-01 

B- 138 
CLASS D .6HAD ,.. 1 KICRON STABU: OOLD 197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 2. 56E-01 2. 26E-01 3.03E-04 1.52E-01 6. 34E-01 

2.00E-01 2.}9E-01 2.01E-01 2. 96E-07 1.47E-01 6. 27E-01 

3.00E-01 2.97E-01 1.79E-01 O.OOE+OO 1. 43E-01 6. 19E-01 

I 4.00E-01 3.10E-01 1.60E-01 O.OOE+OO 1. 38E-01 6.09E-01 

5.00E-01 3. 21E-01 1. 43E-01 O.OOE+oo 1. 33E-01 5. 97E-01 

6.00E-01 3. 29E-01 1.27E-01 O.OOE+OO 1. 28E-01 5. 84E-01 

7.00E-01 3. 36E-01 1. 13E-01 O.OOE+OO 1. 22E-01 5.71E-01 

8.00E-01 3.40E-01 1.01E-01 O.OOE+OO 1. 16E-01 5.57E-01 

9.00E-01 3. 44E-01 8.96E-02 O.OOE+oo 1.09E-01 5. 42E-01 

1.00E+00 3. 45E-01 7. 97E-02 O.OOE+OO 1.02E-01 5. 27E-01 

2.00E+00 3. 23E-01 2. 42E-02 O.OOE+oo 4. 65E-02 3.93E-01 

3.00E+00 2.71E-01 7. 13E-03 O.OOE+OO 1. 85E-02 2. 97E-01 

4.00E+00 2.20E-01 2.05E-03 O.OOE+oo 7.03E-03 2. 29E-01 

5.00E+OO 1. 76E-01 5. 81E-04 O.OOE+OO 2. 62E-03 1. 79E-01 

6.00E+00 1.40E-01 1. 62E-04 O.OOE+oo 9. 69E-04 1.41E-01 

7.00E+00 1. 11E-01 4.47E-05 O.OOE+OO 3. 57E-04 1. 11E-01 

8.00E+00 8.81E-02 1.22E-05 O.OOE+OO 1. 32E-04 8. 83E-02 

9.00E+00 7.00E-02 3. 32E-06 O.OOE+OO 4. 84E-05 7.00E-02 

1.00E+01 5.55E-02 8.96E-07 O.OOE+oo 1. 78E-05 5.55E-02 

2.00E+01 5. 51E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5. 51E-03 

3.00E+01 5.47E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5. 47E-04 

4.00E+01 5. 43E-05 O.OOE+OO O.OOE+OO O.OOE+OO 5. 43E-05 

5.00E+01 5. 39E-06 O.OOE+oo O.OOE+oo O.OOE+oo 5. 39E-06 

6.00E+01 5. 35E-07 O.OOE+OO O.OOE+OO O.OOE+OO 5. 35E-07 

7.00E+01 5.30E-08 O.OOE+OO O.OOE+oo O.OOE+OO 5.30E-08 

B-139 
CLASS D AHA» ... 1 KICRON STABLE roLD 197 

TIME AFTER . FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 4.S6E-03 6.00E-05 

2.00E-OI I.IIE-02 7. 24E-04 

3.00E-OI I.77E-02 2. 55E-03 

4.00E-ol 2.47E-02 5. 67E-03 

5.00E-Ol 3.20E-02 9. 95E-03 

6.00E-Ol 3. 96E-02 1. 52E-02 

7.00E-Ol 4.72E-02 2.11E-02 

S.OOE-OI 5.5IE-02 2. 74E-02 

9.00E-OI 6.30E-02 3.40E-02 

I.OOE+OO 7.09E-02 7.09E-02 4.07E-02 4.07E-02 

2.00E+OO 7.S3E-02 1.49E-OI 5. 59E-02 9. 66E-02 

3.00E+OO 6.S7E-02 2.1SE-0l 2.S0E-02 1.2SE-OI 

4.00E+OO S.65E-02 2. 74E-Ol 1.I5E-02 I.36E-Ol 

5.00E+OO 4.S5E-02 3.20E-Ol 4.4IE-03 I.40E-Ol 

6.00E+OO 3. 63E-02 3.56E-0l 1. 65E-03 1. 42E-OI 

7.00E+OO 2.SSE-02 3.SSE-OI 6.I2E-04 1. 43E-Ol 

S.OOE+OO 2. 29E-02 4.0SE-0l 2.26E-04 1.43E-OI 

9.00E+OO 1.S2E-02 4. 26E-Ol S.32E-OS 1.43E-Ol 

I.OOE+Ol 1. 44E-02 4.4IE-0l 3.06E-OS 1.43E-OI 

2.00E+OI 1. 43E-03 4.91E-OI O.OOE+OO 1.43E-Ol 

3.00E+OI 1. 42E-04 4.9SE-0l O.OOE+OO 1. 43E-Ol 

4.00E+OI 1.41E-OS 4. 96E-Ol O.OOE+OO 1. 43E-Ol 

S.OOE+OI 1.40E-06 4. 96E-Ol O.OOE+OO 1. 43E-Ol 

6.00E+Ol 1. 39E-07 4. 96E-Ol O.OOE+OO 1.43E-OI 

7.00E+Ol 1.3SE-OS 4.96E-OI O.OOE+OO 1.43E-OI 

B-140 
CLASS D AHA]) - 1 HICB.OB STABLE MEllCDRY 200 

(OIlGABIC.COHPOUBDS) 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.9lE-Ol 2. 26E-Ol 3.03E-04 2. 17E-02 6. 39E-Ol 

2.00E-Ol 4.35E-Ol 2.0lE-Ol 2. 96E-07 2. 28E-03 6.39E-Ol 

3.00E-Ol 4. 58E-Ol 1. 79E-Ol O.OOE+OO 4.l5E-04 6. 38E-Ol 

4.00E-Ol 4. 78E-Ol 1.60E-Ol O.OOE+OO 1.85E-04 6. 38E-Ol 

5.00E-Ol 4. 95E-bl 1. 43E-Ol O.OOE+OO 1.2lE-04 6. 37E-Ol 

6.00E-Ol 5.l0E-0l 1.27E-Ol O.OOE+OQ 8. 47E-05 6.37E-Ol 

7.00E-Ol 5. 23E-Ol 1.BE-Ol O.OOE+OO 5.98E-05 6.37E-Ol 

8.00E-Ol 5. 35E-Ol 1.OlE-Ol O.OOE+OO 4. 23E-05 6.36E-Ol 

9.00E-Ol 5. 46E-Ol 8. 96E-02 O.OOE+OO 2. 99E-05 6. 36E-Ol 

1.OOE+OO 5.56E-Ol 7. 97E-02 O.OOE+OO 2.l2E-05 6. 35E-Ol 

2.00E+OO 6.06E-Ol 2. 42E-02 O.OOE+OO 7.04E-07 6.30E-Ol 

3.00E+OO 6.l8E-0l 7.l3E-03 O.OOE+OO 3. 82E-08 6.25E-Ol 

4.00E+OO 6.l8E-Ol 2.05E-03 O.OOE+OO O.OOE+OO 6. 2 OE-O 1 

5.00E+OO 6.l5E-Ol 5.8lE-04 O.OOE+OO O.OOE+OO 6.l5E-Ol 

6.00E+OO 6.lOE-Ol 1. 62E-04 O.OOE+OO O.OOE+OO 6.l0E-Ol 

7.00E+OO 6.05E-Ol 4.47E-05 O.OOE+OO O.OOE+OO 6.05E-Ol 

8.00E+OO 6.00E-Ol 1. 22E-05 O.OOE+OO O.OOE+OO 6.00E-Ol 

9.00E+OO 5.95E-0l 3. 32E-06 O.OOE+OO O.OOE+OO 5. 95E-Ol 

1.OOE+Ol 5.90E-Ol 8. 96E-07 O.OOE+OO O.OOE+OO 5.90E-Ol 

2.00E+Ol 5. 44E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 5.44E-Ol 

3.00E+Ol 5.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 5.02E-Ol 

4.00E+Ol 4. 63E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-Ol 

5.00E+Ol 4.27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-Ol 

6.00E+Ol 3.94E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 94E-Ol 

7.00E+Ol 3.6'4E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 64E-Ol 

8.00E+Ol 3.36E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.36E-Ol 

9.00E+Ol 3. llE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.llE-Ol 

l.OOE+02 2. 88E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 88E-Ol 

2.00E+02 1.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-Ol 

3.00E+02 7.66E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.66E-02 

4.00E+02 5.0fE-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.0lE-02 

5.00E+02 3.89E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 89E-02 

6.00E+02 3.40E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.40E-02 

}.OOE+02 3.l9E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.l9E-02 

8.00E+02 3.08E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.08E-02 

9.00E+02 3.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.03E-02 

l.OOE+03 2. 99E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 99E-02 

2.00E+03 2.78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 78E-02 

4.00E+03 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

8.00E+03 1. 84E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 84E-02 

1.OOE+04 1.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-02 

2.00E+04 7. 99E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7. 99E-03 

B-l4l 
CLASS D AMAD =- 1 HICHON STABLE H.KB.CUB.Y 200 

(ORGANIC COMPOUNDS) 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 37E-04 4.54E-10 

2.00E-0l S.SlE-04 2. 79E-09 

3.00E-01 9.49E-04 6.9SE-09 

4.00E-01 1.33E-03 1. 25E-OS 

5.00E-01 1. 73E-03 1.90E-OS 

6.00E-0l 2.1SE-03 2.62E-OS 

7.00E-01 2. 57E-03 3. 36E"",OS 

S.OOE-Ol 3.01E-03 4.13E-OS 

9.00E-Ol 3.4SE-03 4.S9E-OS 

1.00E+OO 3.91E-03 3.91E-03 S.64E-OS S.64E-OS 

2.00E+OO 4.S2E-03 8.13E-03 S.17E-OS 1.14E-07 

3.00E+OO S.05E-03 1. 38E-02 2. 12E-08 1.41E-07 

4.00E+OO S.09E-03 1. 89E-02 1.1OE-08 1. 52E-07 

5.00E+OO S.07E-03 2. 39E-02 O.OOE+OO 1. 57E-07 

6.00E+OO S.03E-03 2.90E-02 O.OOE+OO 1.S8E-07 

7.00E+OO 4. 99E-03 3.40E-02 O.OOE+OO 1.S9E-07 

S.OOE+OO 4.9SE-03 3.89E-02 O.OOE+OO 1. 59E-07 

9.00E+OO 4.90E-03 4.38E-02 O.OOE+OO 1.S9E-07 

1.00E+Ol 4.S6E-03 4.87E-02 O.OOE+OO 1.S9E-07 

2.00E+01 4. 46E-03 9. SOE-02 O.OOE+OO 1.59E-07 

3.00E+01 4.09E-03 1. 38E-Ol O.OOE+OO 1. 59E-07 

4.00E+Ol 3.7SE-03 1. 77E-Ol O.OOE+OO 1.S9E-07 

S.OOE+01 3. 44E-03 2. 12E-Ol O.OOE+OO 1. 59E-07 

6.00E+Ol 3.1SE-03 2.4SE-01 O.OOE+OO 1. 59E-07 

7.00E+01 2. 89E-03 2.75E-Ol O.OOE+OO 1.S9E-07 

S.OOE+01 2. 65E-03 3.03E-01 O.OOE+OO 1. 59E-07 

9.00E+01 2. 43E-03 3. 28E-Ol O.OOE+OO 1.S9E-07 

1.00E+02 2. 23E-03 3.51E-Ol O.OOE+OO 1.S9E-07 

2.00E+02 9.39E-04 S.OOE-01 O.OOE+OO 1.S9E-07 

3.00E+02 3. 96E-04 S.63E-Ol O.OOE+OO 1. 59E-07 

4.00E+02 1. 68E-04 S.89E-Ol O.OOE+OO 1. 59E-07 

S.OOE+02 7.18E-05 6.00E-Ol O.OOE+OO 1.S9E-07 

6.00E+02 3.14E-05 6.0SE-Ol O.OOE+OO 1. 59E-07 

7.00E+02 1. 44E-05 6.07E-Ol O.OOE+OO 1. 59E-07 " S.OOE+02 7.2SE-06 6.08E-01 O.OOE+OO 1. 59E-07 

9.00E+02 4.26E-06 6.09E-01 O.OOE+OO 1. 59E-07 

1.00E+03 2.9SE-06 6.09E-01 O.OOE+OO 1. 59E-07 

2.00E+03 1.93E-06 6.11E-0l O.OOE+OO 1. 59E-07 

4.00E+03 1.6SE-06 6.1SE-01 O.OOE+OO 1.S9E-07 

8.00E+03 1.27E-06 6. 21E-0l O.OOE+OO 1. 59E-07 

1.00E+04 1.11E-06 6. 23E-Ol O.OOE+OO 1. 59E-07 

2.00E+04 5.S4E-07 6.31E-Ol O.OOE+OO 1.59E-07 

B-142 
CLASS D AHAD .. 1 MICRON BALFLIFE ... 1 .. 38&+03 DAYS 'l"IIALLIDH 204 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 89E-Ol 2. 26E-Ol 3.03E-04 2. 17E-02 6. 37E-01 

2.00E-01 4. 31E-01 2.01E-01 2. 96E-07 2. 28E-03 6. 34E-01 

3.00E-Ol 4.51E-01 1.79E-01 O.OOE+oo 4. 15E-04 6. 31E-01 

4.00E-01 4. 68E-01 1.60E-01 O.OOE+OO 1. 85E-04 6. 28E-01 

5.00E-01 4. 82E-01 1. 43E-Ol O.OOE+oo 1.21E-04 6. 25E-01 

6.00E-01 4. 94E-Ol 1. 27E-01 O.OOE+OO 8. 46E-05 6. 21E-01 

7.00E-Ol 5.05E-01 1. 13E-01 O.OOE+OO 5. 98E-05 6. 18E-01 

8.00E-Ol 5. 13E-01 1.01E-01 O.OOE+OO 4. 23E-05 6. 14E-01 

9.00E-01 5.21E-Ol 8.95E-02 O.OOE+OO 2.99E-05 6.1OE-01 

1.00E+00 5. 27E-01 7. 96E-02 O.OOE+OO 2. 12E-05 6.07E-01 

2.00E+00 5. 45E-01 2.42E-02 O.OOE+oo 7.03E-07 5. 69E-Ol 

3.00E+00 5. 24E-01 7. 12E-03 O.OOE+OO 3. 82E-08 5. 32E-01 

4.00E+00 4. 94E-01 2.05E-03 O.OOE+OO O.OOE+OO 4. 96E-01 

5.00E+00 4. 62E-01 5. 79E-04 O.OOE+OO O.OOE+OO 4. 63E-01 

6.00E+00 4. 31E-01 .1.62E-04 O.OOE+OO O.OOE+OO 4. 31E-01 

7.00E+00 4.02E-01 4. 46E-05 O.OOE+OO O.OOE+OO 4.02E-01 

8.00E+00 3.75E-Ol 1. 22E-05 O.OOE+OO O.OOE+OO 3.75E-01 

9.00E+00 3.50E-01 3. 31E-06 O.OOE+OO O.OOE+OO 3.50E-01 

1.00E+Ol 3. 26E-01 8.92E-07 O.OOE+OO O.OOE+OO 3. 26E-01 

2.00E+Ol 1.62E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1. 62E-Ol 

3.00E+Ol 8.08E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.08E-02 

4.00E+Ol 4.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.02E-02 

5.00E+Ol 2.00E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.00E-02 

6.00E+Ol 9. 95E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9. 95E-03 . 7.00E+Ol 4.95E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.95E-03 

8.00E+Ol 2. 46E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 46E-03 

9.00E+Ol 1.23E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 23E-03 

1.00E+02 6.1OE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.1OE-04 

2.00E+02 5. 67E-07 O.OOE+OO O.OOE+oo O.OOE+OO 5. 67E-07 

B-143 
CLASS D AMAD = 1 KICRON BALFLIFE= 1.J8E+03 DAYS THALLIUM 204 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-Ol 1. 99E-03 O.OOE+OO 

2.00E-OI 4.B6E-03 O.OOE+OO 

3.00E-OI 7. 92E-03 O.OOE+OO 

4.00E-OI I.l1E-02 O.OOE+OO 

5.00E-OI I.44E-02 O.OOE+OO 

6.00E-OI I.7BE-02 O.OOE+OO 

7.00E-OI 2.12E-02 O.OOE+OO 

B.OOE-OI 2.4BE-02 O.OOE+OO 

9.00E-OI 2.B3E-02 O.OOE+OO 

I.OOE+OO 3.20E-02 3.20E-02 O.OOE+OO O.OOE+OO 

2.00E+OO 3. 75E-02 6.95E-02 O.OOE+OO O.OOE+OO 

3.00E+OO 3.71E-02 I.07E-OI O.OOE+OO O.OOE+OO 

4.00E+OO 3. 53E-02 I.42E-Ol O.OOE+OO O.OOE+OO 

5.00E+OO 3.31E-02 1. 75E-Ol O.OOE+OO O.OOE+OO 

6.00E+OO 3.09E-02 2.06E-OI O.OOE+OO O.OOE+OO 

7.00E+OO 2.B9E-02 2. 34E-OI O.OOE+OO O.OOE+OO 

B.OOE+OO 2. 69E-02 2.61E-OI O.OOE+OO O.OOE+OO 

9.00E+OO 2.5IE-02 2.B6E-OI O.OOE+OO O.OOE+OO 

I.OOE+Ol 2. 34E-02 3.lOE-Ol O.OOE+OO O.OOE+OO 

2.00E+OI 1.I7E-02 4.70E-Ol O.OOE+OO O.OOE+OO 

3.00E+Ol 5. BOE-03 5. 49E-Ol O.OOE+OO O.OOE+OO 

4.00E+Ol 2.BBE-03 5.B6E-OI O.OOE+OO O.OOE+OO 

5.00E+Ol 1. 44E-03 6.03E-OI O.OOE+OO O.OOE+OO 

6.00E+Ol 7.14E-04 6.IOE-Ol O.OOE+OO O.OOE+OO 

7.00E+Ol 3. 55E-04 6.12E-Ol O.OOE+OO O.OOE+OO 

B.OOE+OI 1.77E-04 6.l1E-OI O.OOE+OO O.QOE+OO 

9.00E+OI B.BOE-05 6.lOE-Ol O.OOE+OO O.OOE+OO 

I.OOE+02 4.3BE-05 6.07E-OI O.OOE+OO O.OOE+OO 

2.00E+02 4.07E-OB 5.7BE-Ol O.OOE+OO O.OOE+OO 

B-144 
CLASS D AHAD .. 1 HICIlOH S'l'ABLE mALLIUH 205 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3. 89E-OI 2. 26E-Ol 3.03E-04 2.17E-02 6. 37E-Ol 

2.00E-Ol 4.31E-Ol 2.01E-Ol 2. 96E-07 2. 28E-03 6.34E-Ol 

3.00E-OI 4.51E-Ol 1.79E-Ol O.OOE+OO 4. 15E-04 6.31E-OI 

4.00E-OI 4. 68E-OI 1.60E-OI O.OOE+OO 1.85E-04 6. 28E-Ol 

5.00E-0l 4. 82E-Ol 1. 43E-Ol O.OOE+OO 1.2IE-04 6.25E-OI 

6.00E-Ol 4. 94E-Ol 1.27E-Ol O.OOE+OO 8.47E-05 6.2lE-Ol 

7.00E-Ol 5.05E-Ol 1.l3E-Ol O.OOE+OO 5. 98E-05 6.l8E-Ol 

8.00E-Ol 5.l4E-Ol 1.OlE-Ol O.OOE+OO 4. 23E-05 6.l4E-OI 

9.00E-OI S.2lE-0l 8. 96E-02 O.OOE+OO 2. 99E-OS 6.l1E-0l 

1.OOE+OO S.27E-OI 7.97E-02 O.OOE+OO 2.l2E-OS 6.07E-Ol 

2.00E+OO 5.4SE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 S. lOE-Ol 

3.00E+OO 5.2SE-Ol 7.l3E-03 O.OOE+OO 3. 82E-08 5. 32E-Ol 

4.00E+OO 4.9SE-Ol 2.05E-03 O.OOE+OO O.OOE+OO 4.97E-OI 

5.00E+OO 4. 63E-OI 5.8lE-04 O.OOE+OO O.OOE+OO 4. 64E-OI 

6.00E+OO 4. 33E-Ol 1.62E-04 O.OOE+OO O.OOE+OO 4. 33E-Ol 

7.00E+OO 4.04E-Ol 4.47E-OS O.OOE+OO O.OOE+OO 4.04E-Ol 

8.00E+OO 3. 77E-Ol I. 22E-05 O.OOE+OO O.OOE+OO 3. 77E-Ol 

9.00E+OO 3. 52E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 3.S2E-OI 

1.OOE+Ol 3. 28E-Ol 8. 96E-07 O.OOE+OO O.OOE+OO 3. 28E-OI 

2.00E+Ol 1. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 64E-Ol 

3.00E+Ol 8.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.20E-02 

4.00E+Ol 4.lOE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.lOE-02 

5.00E+Ol 2.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-02 

6.00E+Ol 1.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-02 

7.00E+Ol 5.l3E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5.l3E-03 

8.00E+Ol 2. 57E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-03 

9.00E+Ol 1. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 28E-03 

1.OOE+02 6.4lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.4lE-04 

2.00E+02 6. 27E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 27E-07 

B-145 
CLASS D AMAD = 1 MICIlOII STABLE THALLIUM 205 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1. 99E-03 O.OOE+OO 

2.00E-Ol 4.S6E-03 O.OOE+OO 

3.00E-Ol 7.92E-03 O.OOE+OO 

4.00E-Ol 1.llE-02 O.OOE+OO 

S.OOE-Ol 1.44E-02 O.OOE+OO 

6.00E-Ol 1.7SE-02 O.OOE+OO 

7.00E-Ol 2.l2E-02 O.OOE+OO 

S.OOE-Ol 2.4SE-02 O.OOE+OO 

9.00E-Ol 2.S4E-02 O.OOE+OO 

1.OOE+OO 3.20E-02 3.20E-02 O.OOE+OO O.OOE+OO 

2.00E+OO 3.75E-02 6.9SE-02 O.OOE+OO O.OOE+OO 

3.00E+OO 3. 72E-02 1.07E-Ol O.OOE+OO O.OOE+OO 

4.00E+OO 3. 54E-02 1. 42E-Ol O.OOE+OO O.OOE+OO 

5.00E+OO 3. 32E-02 1.7SE-Ol O.OOE+OO O.OOE+OO 

6.00E+OO 3.l0E-02 2.06E-Ol O.OOE+OO O.OOE+OO 

7.00E+OO 2.90E-02 2.35E-Ol O.OOE+OO O.OOE+OO 

S.OOE+OO 2.70E-02 2. 62E-Ol O.OOE+OO O.OOE+OO 

9.00E+OO 2.S2E-02 2.SSE-Ol O.OOE+OO O.OOE+OO 

1.OOE+Ol 2.3SE-02 3.llE-Ol O.OOE+OO O.OOE+OO 

2.00E+Ol 1.lSE-02 4. 75E-Ol O.OOE+OO O.OOE+OO 

3.00E+Ol 5.S9E-03 5. S7E-Ol O.OOE+OO O.OOE+OO 

4.00E+Ol 2. 94E-03 5.9SE-Ol O.OOE+OO O.OOE+OO 

S.OOE+Ol 1. 47E-03 6.19E-Ol O.OOE+OO O.OOE+OO 

6.00E+Ol 7. 36E-04 6.29E-Ol O.OOE+OO O.OOE+OO 

7.00E+Ol 3.6SE-04 6. 34E-Ol O.OOE+OO O.OOE+OO 

S.OOE+Ol I.S4E-04 6.37E-Ol O.OOE+OO O.OOE+OO 

9.00E+Ol 9.2lE-OS 6.3SE-Ol O.OOE+OO O.OOE+OO 

1.OOE+02 4.60E-OS 6.3SE-Ol O.OOE+OO O.OOE+OO 

2.00E+02 4. SOE-OS 6.39E-Ol O.OOE+OO O.OOE+OO 

B-146 
CLASS D AKAD - 1 HICB.OH BALl'LII'E.... 8.14£+03 DAYS LEAD 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2. 65E-Ol 2. 26E-Ol 3.03E-04 1.47E-Ol 6. 38E-Ol 

2.00E-OI 2. 99E-OI 2.0IE-01 2. 96E-07 1. 36E-Ol 6. 36E-OI 

3.00E-Ol 3. 25E-Ol 1. 79E-Ol O.OOE+oo 1. 29E-01 6. 33E-OI 

4.00E-OI 3.45E-OI 1.60E-Ol O.OOE+OO I. 24E-OI 6. 29E-Ol 

5.00E-Ol 3. 63E-Ol 1. 43E-Ol O.OOE+OO 1.19E-01 6. 24E-Ol 

6.00E-OI 3. 17E-OI 1. 27E-OI O.OOE+OO I. 13E-OI 6.17E-Ol 

7.00E-Ol 3.90E-OI 1. 13E-01 O.OOE+OO 1.08E-Ol 6. 11E-Ol 

8.00E-OI 4.0IE-01 1.0IE-01 O.OOE+OO 1.02E-OI 6.03E-OI 

9.00E-OI 4.IOE-01 8. 96E-02 O.OOE+OO 9.60E-02 5.96E-OI 

I.OOE+OO 4.18E-Ol 7. 97E-02 O.OOE+OO 9.00E-02 5. 88E-Ol 

2.00E+00 4. 56E-Ol, 2. 42E-02 O.OOE+OO 4.06E-02 5.2IE-Ol 

3.00E+00 4. 55E-Ol 7. 13E-03 O.OOE+OO 1.6IE-02 4. 78E-OI 

4.00E+00 4.43E-Ol 2.05E-03 O.OOE+OO 6. 13E-03 4.5IE-OI 

5.00E+00 4. 28E-Ol 5.80E-04 O.OOE+OO 2. 28E-03 4.3IE-Ol 

6.00E+00 4. 13E-01 1.62E-04 O.OOE+OO 8.45E-04 4.14E-Ol 

7.00E+00 3. 98E-OI 4. 47E-05 O.OOE+OO 3.IIE-04 3. 98E-Ol 

8.00E+00 3. 84E-Ol I. 22E-05 O.OOE+OO I. 15E-04 3.84E-OI 

9.00E+00 3.71E-OI 3. 32E-06 O.OOE+OO 4. 22E-05 3. 71E-OI 

I.OOE+OI 3. 58E-Ol 8.96E-07 O.OOE+oo I. 55E-05 3. 58E-OI 

2.00E+OI 2. 65E-OI O.OOE+OO O.OOE+OO O.OOE+OO 2. 65E-OI 

3.00E+OI 2.12E-Ol O.OOE+OO O.OOE+OO O.OOE+oo 2.12E-OI 

4.00E+OI 1.80E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.80E-Ol 

5.00E+OI 1.6IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.6IE-OI 

6.00E+Ol 1.49E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.49E-OI 

7.00E+Ol 1.4IE-01 O.OOE+OO O.OOE+OO O.OOE+OO 1.4IE-OI 

8.00E+OI I. 35E-01 O.OOE+OO O.OOE+OO O.OOE+OO 1. 35E-OI 

9.00E+OI 1.3IE-OI O.OOE+OO O.OOE+OO O.OOE+oo 1.31E-OI 

1.00E+02 I. 27E-OI O.OOE+OO O.OOE+OO O.OOE+OO I. 27E-OI 

2.00E+02 1.04E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-01 

3.00E+02 8. 82E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 82E-02 

4.00E+02 7. 76F02 O.OOE+OO O.OOE+oo O.OOE+OO 7.76E-02 

5.00E+02 7.0IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.0IE-02 

6.00E+02 6. 48E-02 O.OOE+OO O.OOE+oo O.OOE+OO 6. 48E-02 

7.00E+02 6.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.09E-02 

8.00E+02 5.80E-02 O.OOE+OO O.OOE+OO O.OOE+oo 5.80E-02 

9.00E+02 5.59E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 59E-02 . ,. , 1.00E+03 5.4IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.4IE-02 

2.00E+03 4.48E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 48E-02 

4.00E+03 3. 28E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 28E-02 

8.00E+03 1.17E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.17E-02 

1.00E+04 1.30E-02 O.OOE+oo O.OOE+OO O.OOE+OO 1.30E-02 

2.00E+04 2.17E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.17E-03 

B-147 
CLASS D AHAD - 1 HICROH BAJ.FLU'E= 8.14E+03 DAYS LEAD 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

" 

1.OOE-Ol 8. 68E-04 5.91E-05 

2.00E-Ol 2.01E-03 7.03E-04 

3.00E-Ol 3.28E-03 2. 45E-03 

4.00E-Ol 4. 63E-03 5. 38E-03 

5.00E-Ol 6.06E-03 9.35E-03 

6.00E-Ol 7. 55E-03 1.4lE-02 

7.00E-Ol 9.l0E-03 1.95E-02 

8.00E-Ol 1.07E-02 2. 52E-02 

9.00E-0l 1. 23E-02 3. llE-02 

1.OOE+OO 1.40E-02 1.40E-02 3.7lE-02 3.7lE-02 

2.00E+OO 1.76E-02 3.l6E-02 4.94E-02 8. 65E-02 

3.00E+OO 1. 79E-02 4. 95E-02 2. 45E-02 1. llE-Ol 

4.00E+OO 1. 73E-02 6. 68E-02 1.OOE-02 1.2lE-OI 

5.00E+OO 1. 65E-02 8. 32E-02 3. 84E-03 1.25E-OI 

6.00E+OO 1. 56E-02 9. 88E-02 1. 44E-03 1.26E-0l 

7.00E+OO 1. 47E-02 1. 14E-Ol 5. 33E-04 1.27E-Ol 

8.00E+OO 1.39E-02 1. 28E-0l 1.97E-04 1.27E-Ol 

9.00E+OO 1. 32E-02 1.4lE-Ol 7. 25E-05 1. 27E-Ol 

1.OOE+Ol 1.25E-02 1. 53E-Ol 2. 67E-05 1.27E-Ol 

2.00E+Ol 7. 13E-03 2. 46E-Ol O.OOE+OO 1.27E-Ol 

3.00E+Ol 4.l4E-03 2. 99E-Ol O.OOE+OO 1.27E-Ol 

4.00E+Ol 2. 46E-03 3.30E-Ol O.OOE+OO 1. 27E-Ol 

5.00E+Ol 1.51E-03 3. 49E-Ol O.OOE+OO 1. 27E-0l 

6.00E+Ol 9. 73E-04 3.60E-Ol O.OOE+OO 1.27E-Ol 

7.00E+Ol 6. 67E-04 3. 68E-Ol O.OOE+OO 1. 26E-Ol 

8.00E+Ol 4.91E-04 3. 73E-Ol O.OOE+OO 1.26E-Ol 

9.00E+Ol 3. 88E-04 3.77E-Ol O.OOE+OO 1.26E-0l 

1.OOE+02 3. 25E-04 3.80E-Ol O.OOE+OO 1. 26E-Ol 

2.00E+02 1~76E-04 4.00E-Ol O.OOE+OO 1.25E-Ol 

3.00E+02 1.20E-04 4.1lE-0l O.OOE+OO 1. 24E-Ol 

4.00E+02 8. 23E-05 4.l7E-0l O.OOE+OO 1.23E-Ol 

5.00E+02 5. 67E-05 4.21E-Ol O.OOE+OO 1. 22E-Ol 

6.00E+02 3. 95E-05 4. 22E-Ol O.OOE+OO 1.21E-Ol 

7.00E+02 2. 78E-05 4.2lE-Ol O.OOE+OO 1.20E-Ol 

8.00E+02 2.00E-05 4.20E-Ol O.OOE+OO 1.19E-Ol 

9.00E+02 1. 46E-05 4.18E-Ol O.OOE+OO 1.l8E-OI 

I.OOE+03 l.lOE-05 4.I6E-OI O.OOE+OO 1.17E-Ol 

2.00E+03 3. 24E-06 3. 87E-OI O.OOE+OO 1.07E-OI 

4.00E+03 2. 28E-06 3.3IE-0l O.OOE+OO 9.05E-02 

8.00E+03 I. 23E-06 2.4IE-OI O.OOE+OO 6. 44E-02 

I.OOE+04 9.0lE-07 2.05E-Ol O.OOE+OO 5. 43E-02 

2.00E+04 1. 92E-07 9.05E-02 O.OOE+OO 2. 32E-02 

B-148 
CLASS D AHAD - 1 HICltOR STABLE BISHU'lB 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 33E-0l 2. 26E-Ol 3.03E-04 1.54E-Ol 6.l3E-Ol 

2.00E-Ol 2.31E-Ol 2.0lE-Ol 2. 96E-07 1. 52E-Ol 5.~4E-Ol 

3.00E-Ol 2. 27E-0l 1. 79E-Ol O.OOE+OO 1.49E-Ol 5.55E-Ol 

4.00E-0l 2. 23E-Ol 1.60E-OI O.OOE+OO 1. 45E-Ol 5. 28E-Ol 

5.00E-Ol 2.l8E-0l 1. 43E-Ol O.OOE+OO 1.4IE-0l 5.0lE-Ol 

6.00E-Ol 2.l3E-0l 1. 27E-Ol O.OOE+OO 1. 35E-Ol 4. 75E-Ol 

7.00E-Ol 2.07E-0l I.l3E-OI O.OOE+OO 1. 29E-OI 4. 49E-OI 

8.00E-OI 2.02E-OI 1.0lE-OI O.OOE+OO 1. 22E-OI 4. 25E-OI 

9.00E-Ol 1. 97E-OI 8. 96E-02 O.OOE+OO 1. 16E-OI 4.02E-Ol 

1.OOE+OO 1.91E-OI 7. 97E-02 O.OOE+OO 1.09E-Ol 3. 79E-Ol 

2.00E+OO 1. 43E-0l 2. 42E-02 O.OOE+OO 4. 95E-02 2.17E-0l 

3.00E+OO I.llE-OI 7.l3E-03 O.OOE+OO 1.97E-02 1. 38E-Ol 

4.00E+OO 8.97E-02 2.05E-03 O.OOE+OO 7. 49E-03 9. 92E-02 

5.00E+OO 7. 53E-02 5.8IE-04 O.OOE+90 2.79E-03 7. 87E-02 

6.00E+OO 6.45E-02 1. 62E-04 O.OOE+OO 1.03E-03 6. 57E-02 

7.00E+OO 5.57E-02 4. 47E-05 O.OOE+OO 3.8lE-04 5.62E-02 

8.00E+OO 4.84E-02 1. 22E-05 O.OOE+OO 1.40E-04 4. 85E-02 

9.00E+OO 4.2lE-02 3. 32E-06 O.OOE+OO 5.l6E-05 4.21E-02 

1.OOE+Ol 3. 66E-02 8. 96E-07 O.OOE+OO 1.90E-05 3.66E-02 

2.00E+Ol 9.I5E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.l5E-03 

3.00E+OI 2.29E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 29E-03 

4.00E+Ol 5.72E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5.72E-04 

5.00E+Ol 1. 43E-04 O.OOE+OO O.OOE+OO O.OOE+OO I.43E-04 

6.00E+Ol 3. 58E-05 O.OOE+OO O.OOE+OO O.OOE+OO 3. 58E-05 

7.00E+OI 8. 95E-06 O.OOE+OO O.OOE+OO O.OOE+OO 8. 95E-06 

8.00E+OI 2. 24E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 24E-06 

9.00E+OI 5. 59E-07 O.OOE+OO O.OOE+OO O.OOE+OO 5. 59E-07 

1.OOE+02 I.40E-07 O.OOE+OO O.OOE-t:OO O.OOE+OO I.40E-07 

B-149 
CLASS D AIfAD .. 1 MICRO. STABLE BlSHU'lII 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

---------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2. 63E-02 6.04E-05 

2.00E-Ol 5. 48E-02 7. 33E-04 

3.00E-Ol 8. llE-02 2.60E-03 

4.00E-Ol 1.05E-Ol . 5.8lE-03 

5.00E-Ol 1. 28E-Ol 1.02E-02 

6.00E-Ol 1. 49E-Ol 1. 56E-02 

7.00E-Ol 1. 68E-Ol 2.l8E-02 

8.00E-Ol 1. 86E-Ol 2. 84E-02 

9.00E-Ol 2.02E-Ol 3. 54E-02 

1.OOE+OO 2. 17E-Ol 2.l7E-Ol 4. 24E-02 4. 24E-02 

2.00E+OO 1.03E-Ol 3.2lE-Ol 5.92E-02 1.02E-Ol 

3.00E+OO 4. 98E-02 3.70E-Ol 2. 98E-02 1.3lE-Ol 

4.00E+OO 2.6lE-02 3.96E-Ol 1.22E-02 1. 44E-Ol 

5.00E+OO 1. 59E-02 4.l2E-Ol 4.70E-03 1. 48E-Ol 

6.00E+OO 1.12E-02 4. 23E-Ol l.76E-03 1.50E-Ol 

7.00E+OO 8. 85E-03 4.32E-Ol 6. 52E-04 1.5lE-Ol 

8.00E+OO 7. 38E-03 4.40E-Ol 2.4lE-04 1.SlE-Ol 

9.00E+OO 6. 32E-03 4. 46E-Ol B.87E-05 l.5lE-Ol 

1.OOE+01 S.46E-03 4.5lE-Ol 3. 26E-05 1. SlE-Ol 

2.00E+Ol 1. 36E-03 4. 79E-Ol O.OOE+OO 1.5lE-Ol 

3.00E+Ol 3.40E-04 4. 86E-Ol O.OOE+OO 1.5lE-Ol 

4.00E+Ol B.5lE-05 4.8BE-Ol O.OOE+OO 1.S1E-Ol 

5.00E+Ol 2.l3E-OS 4. 88E-Ol O.OOE+OO 1.SlE-Ol 

6 .. 00E+Ol S.32E-06 4.8BE-Ol O.OOE+OO 1.SlE-Ol 

7.00E+Ol 1. 33E-06 4.B8E-Ol O.OOE+OO 1.SlE-Ol 

8.00E+Ol 3. 33E-07 4.B8E-Ol O.OOE+OO 1.SlE-Ol 

9.00E+01 B.3lE-OB 4.BBE-Ol O.OOE+OO 1. 5lE~01 

1.OOE+02 2.07E-OB 4.BBE-Ol O.OOE+OO 1.5lE-Ol 

B-150 
CLASS D AIIAD = 1 HICltON BALFLI.:rE= 1.38&+02 DAYS FOLONIDH 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.6lE-Ol 2. 26E-Ol 3.03E-04 1. S2E-Ol 6. 38E-Ol 

2.00E-Ol 2. 89E-Ol 2.0lE-Ol 2.9SE-07 1.47E-Ol 6.37E-Ol 

3.00E-Ol 3. 13E-0l 1.79E-0l O.OOE+OO 1. 42E-Ol 6.3SE-Ol 

4.00E-Ol 3. 33E-Ol 1.60E-OI O.OOE+OO 1.38E-Ol 6.3lE-Ol 

S.OOE-Ol 3.S0E-Ol 1.42E-Ol O.OOE+OO 1. 33E-Ol 6. 26E-Ol 

6.00E-Ol 3.6SE-Ol 1.27E-Ol O.OOE+OO 1.28E-Ol 6.20E-ol 

7.00E-Ol- 3.79E-Ol 1.13E-Ol O.OOE+OO 1. 22E-Ol 6.13E-0l 

8.00E-Ol 3.90E-Ol 1.OOE-Ol O.OOE+OO 1.lSE-Ol 6.06E-Ol 

9.00E-Ol 4.0lE-Ol 8. 92E-02 O.OOE+OO 1.09E-Ol S.98E-Ol 

1.OOE+OO 4.lOE-Ol 7. 93E-02 O.OOE+OO 1.02E-Ol S.9lE-Ol 

2.00E+OO 4. S6E-Ol 2.40E-02 O.OOE+OO 4.60E-02 S.26E-Ol 

3.00E+OO 4.6SE-Ol 7.02E-03 O.OOE+OO 1. 82E-02 4.90E-Ol 

4.00E+OO 4.6lE-Ol 2. OlE-03 O.OOE+OO 6. 89E-03 4.70E-Ol 

S.OOE+OO 4.S4E-Ol S.66E-04 O.OOE+OO 2.SSE-03 4.S7E-Ol 

6.00E+OO 4.4SE-Ol 1. S7E-04 O.OOE+OO 9.40E-04 4.47E-Ol 

7.00E+OO 4. 37E-Ol 4. 32E-OS O.OOE+OO 3.4SE-04 4. 38E-Ol 

8.00E+OO 4.29E-Ol 1.18E-OS O.OOE+OO 1.26E-04 4. 29E-Ol 

9.00E+OO 4.2lE-Ol 3.l8E-06 O.OOE+OO 4. 63E-OS 4.2lE-Ol 

1.00E+Ol 4.l3E-Ol 8.S3E-07 O.OOE+OO 1.70E-05 4.l3E-Ol 

2.00E+Ol 3. 42E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-Ol 

3.00E+Ol 2. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2. 83E-Ol 

4.00E+Ol 2. 34E-0l O.OOE+OO O.OOE+OO O.OOE+OO 2. 34E-Ol 

S.OOE+Ol 1.94E-0l O.OOE+OO O.OOE+OO O.OOE+OO 1. 94E-Ol 

6.00E+0l 1.6lE-0l O.OOE+OO O.OOE+OO O.OOE+OO 1.6lE-OI 

7.00E+Ol 1. 33E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.33E-Ol 

8.00E+OI 1.lOE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.lOE-OI 

9.00E+0l 9.lOE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.lOE-02 

1.00E+02 7.S3E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.S3E-02 

2.00E+02 1.14E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.14E-02 

3.00E+02 I. 72E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.72E-03 

4.00E+02 2.S9E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. S9E-04 

5.00E+02 3.9lE-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.9IE-OS 

6.00E+02 S.90E-06 O.OOE+OO O.OOE+OO O.OOE+OO S.90E-06 

7.00E+02 8.9lE-07 O.OOE+OO O.OOE+OO O.OOE+OO 8.9lE-07-

8.00E+02 1. 34E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1. 34E-07 

9.00E+02 2.03E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2.03E-08 :~ , ' 

B-151 
CLASS D AMAD == 1 MICRON IlA.LFLIPE- 1.38K+02 DAYS POLONIUM: 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

I.OOE-Ol 2.9SE-OS 3. 26E-04 

2.00E-Ol 6. 78E-OS 1.33E-03 

3.00E-Ol 1.IOE-04 3.S4E-03 

4.00E-Ol 1.SSE-04 7.0SE-03 

S.OOE-Ol 2.02E-04 1.17E-02 

6.00E-Ol 2.S2E-04 1. 74E-02 

7.00E-Ol 3.03E-04 2. 37E-02 

8.00E-OI 3.S6E-04 3.0SE-02 

9.00E-Ol 4.11E-04 3. 76E-02 

1.00E+OO 4. 67E-04 4. 67E-04 4. 47E-02 4. 47E-02 

2.00E+OO 6.0SE-04 I.07E-03 6.0SE-02 1.OSE-0l 

3.00E+OO 6.4lE-04 1.11E-03 3. 33E-02 1.3SE-Ol 

4.00E+OO 6. 42E-04 2. 34E-03 1.70E-02 1.S4E-0l 

5.00E+OO 6. 34E-04 2. 96E-03 1.OOE-02 1. 64E-Ol 

6.00E+OO 6. 23E-04 3.S7E-03 7.2lE-03 1.70E-Ol 

7.00E+OO 6.l2E-04 4.l7E-03 6.l0E-03 1.7SE-OI 

S.OOE+OO 6.0lE-04 4.7SE-03 5. 62E-03 1.SOE-Ol 

9.00E+OO S.S9E-04 5.3lE-03 S.3SE-03 1.8SE-Ol 

1.OOE+Ol S.7SE-04 S.86E-03 S.23E-03 I.S9E-Ol 

2.00E+Ol 4. 79E-04 1.07E-02 4.3lE-03 2. 26E-Ol 

3.00E+Ol 3. 96E-04 1. 44E-02 3.S7E-03 2. S3E-0l 

4.00E+Ol 3.2SE-04 1. 72E-02 2.9SE-03 2. 72E-Ol 

S.OOE+Ol 2.7lE-04 1. 92E-02 2. 44E-03 2.S4E-Ol 

6.00E+Ol 2.2SE-04 2.07E-02 2.02E-03 2. 92E-ol 

7.00E+Ol 1. 86E-04 2. 16E-02 1.67E-03 2.96E-0l 

8.00E+Ol 1.S4E-04 2. 22E-02 1. 39E-03 2. 96E-Ol 

9.00E+Ol 1. 27E-04 2.2SE-02 1.lSE-03 2. 94E-Ol 

1.OOE+02 1.OSE-04 2.2SE-02 9. 49E-04 2.S9E-Ol 

2.00E+02 1.S9E-OS 1.11E-02 1. 43E-04 2.06E-Ol 

3.00E+02 2.40E-06 1.09E-02 2.16E-OS 1.30E-Ol 

4.00E+02 3. 63E-07 6. 66E-03 3. 26E-06 7.93E-02 

S.OOE+02 S.47E-08 4.0SE-03 4. 93E-07 4.81E-02 

".1 

\ " 

B-1S2 
CLASS D AHAD - lllICRON STABLE ASTATUB 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 89E-Ol 2. 26E-Ol 3.03E-04 2.l7E-02 6.37E-Ol 

2.00E-Ol 4.3lE-Ol 2.0lE-Ol 2. 96E-07 2. 28E-03 6. 34E-Ol 

3.00E-Ol 4. SlE-Ol 1.79E-0l O.OOE+OO 4.lSE-04 6.3lE-Ol 

4.00E-Ol 4. 68E-Ol 1.60E-Ol O.OOE+OO 1.8SE-04 6. 28E-Ol 

S.OOE-Ol 4.82E-Ol 1.43E-Ol O.OOE+OO 1.2lE-04 6.2SE-0l 

6.00E-Ol 4. 94E-Ol 1. 27E-Ol O.OOE+OO 8. 47E-OS 6.2lE-Ol 

7.00E-Ol S.OSE-Ol 1.l3E-Ol O.OOE+OO S.98E-OS 6.l8E-Ol 

8.00E-Ol S.14E-Ol I.OlE-Ol O.OOE+OO 4. 23E-OS 6.l4E-Ol 

9.00E-Ol S.2lE-Ol 8. 96E-02 O.OOE+OO 2. 99E-OS 6.llE-0l 

1.OOE+OO S.27E-Ol 7.97E-02 O.OOE+OO 2.l2E-OS 6.07E-Ol 

2.00E+OO S.4SE-Ol 2. 42E-02 O.OOE+OO 7.04E-07 S.70E-Ol 

3.00E+OO S.2SE-Ol 7.l3E-03 O.OOE+OO 3. 82E-08 S.32E-Ol 

4.00E+OO 4.9SE-Ol 2.0SE-03 O.OOE+OO O.OOE+OO 4.97E-0l 

S.OOE+OO 4. 63E-Ol S.8lE-04 O.OOE+OO O.OOE+OO 4. 64E-Ol 

6.00E+OO 4.3.3E-:,Ol 1.62E-04 O.OOE+OO O.OOE+OO 4.33E-Ol 

7.00E+OO 4.04E-Ol 4.47E-OS O.OOE+OO O.OOE+OO 4.04E-Ol 

8.00E+OO 3.17E-Ol 1. 22E-OS O.OOE+OO O.OOE+OO 3. 77E-Ol 

9.00E+OO 3.S2E-Ol 3. 32E-06 O.OOE+OO O.OOE+OO 3.S2E-Ol 

1.OOE+Ol 3. 28E-Ol 8. 96E-07 O.OOE+OO O.OOE+OO 3.28E-Ol 

2.00E+Ol 1. 64E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 64E-Ol 

3.00E+Ol 8.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.20E-02 

4.00E+Ol 4.l0E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.lOE-02 

S.OOE+Ol 2.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.0SE-02 

6.00E+Ol 1.03E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-02 

7.00E+Ol S.13E-03 O.OOE+OO O.OOE+OO O.OOE+OO S.13E-03 

8.00E+Ol 2.57E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-03 

9.00E+Ol 1. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 28E-03 

1.OOE+02 6.4lE-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.4lE-04 

2.00E+02 6.27E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 27E-07 

'. , . 

B- 153 
CI.ASS D AHAD =- 1 HICR.OR STABLE AS'lA7IRE 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 1. 99E-03 O.OOE+OO 

2.00E-Ol 4.B6E-03 O.OOE+OO 

3.00E-ol 7. 92E-03 O.OOE+OO 

4.00E-Ol 1.llE-02 O.OOE+OO 

5.00E-Ol 1. 44E-02 O.OOE+OO 

6.00E-Ol 1.7BE-02 O.OOE+OO 

7.00E-Ol 2.12E-02 O.OOE+OO 

B.OOE-ol 2.4BE-02 O.OOE+OO 

9.00E-Ol 2.B4E-02 O.OOE+OO 

1.OOE+OO 3.20E-02 3.20E-02 O.OOE+OO O.OOE+OO 

2.00E+OO 3. 75E-02 6. 95E-02 O.OOE+OO O.OOE+OO 

3.00E+OO 3. 72E-02 l.07E-Ol O.OOE+OO O.OOE+OO 

4.00E+OO 3. 54E-02 1. 42E-Ol O.OOE+OO O.OOE+OO 

5.00E+OO 3. 32E-02 1. 75E-Ol O.OOE+OO O.OOE+OO 

6.00E+OO 3.10E-02 2.06E-Ol O.OOE+OO O.OOE+OO 

7.00E+OO 2.90E-02 2. 35E-Ol O.OOE+OO O.OOE+OO 

B.OOE+OO 2.70E-02 2. 62E-Ol O.OOE+OO O.OOE+OO 

9.00E+OO 2. 52E-02 2.BBE-Ol O.OOE+OO O.OOE+OO 

1.OOE+Ol 2. 35E-02 3.11E-Ol O.OOE+OO O.OOE+OO 

2.00E+Ol 1.lBE-02 4. 75E-Ol O.OOE+OO O.OOE+OO 

3.00E+0l 5.B9E-03 5. 57E-Ol O.OOE+OO O.OOE+OO 

4.00E+Ol 2. 94E-03 5.9BE-Ol O.OOE+OO O.OOE+OO 

5.00E+Ol 1. 47E-03 6.19E-Ol O.OOE+OO O.OOE+OO 

6.00E+Ol 7. 36E-04 6. 29E-Ol O.OOE+OO O.OOE+OO 

7.00E+Ol 3.6BE-04 6. 34E-Ol O.OOE+OO O.OOE+OO 

B.OOE+Ol l.B4E-04 6.37E-Ol O.OOE+OO O.OOE+OO 

9.00E+Ol 9.21E-05 6.3BE-Ol O.OOE+OO O.OOE+OO 

1.OOE+02 4.60E-05 6.3BE-Ol O.OOE+OO O.OOE+OO 

2.00E+02 4.50E-OB 6.39E-Ol O.OOE+OO O.OOE+OO 

B-154 
CLASS D AHAD - 1 MICRON BALFLIFE= 1.51E-02 DAYS FRANCIUM 223 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 4.02E-03 2. 32E-03 3.11E-06 2. 23E-04 6. 57E-03 

2.00E-Ol 4.60E-05 2.l2E-05 O.OOE+OO 2.4lE-07 6. 74E-05 

3.00E-Ol 4. 98E-07 1.95E-07 O.OOE+OO O.OOE+OO 6.92E-07 

.. ". 

I; :'.' 

" 

B-155 
CLASS D MAD - 1 MICRON BALFLIFE- 7.95£+03 DAYS ACTINIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2. 52E-Ol 2.26E-Ol 3.03E-04 1.56E-Ol 6. 34E-Ol 

2.00E-Ol 2.70E-Ol 2.0lE-Ol 2. 96E-07 1. 56E-Ol 6. 28E-Ol 

3.00E-Ol 2. 87E-Ol 1. 79E-Ol O.OOE+OO 1. 55E-Ol 6. 22E-Ol 

4.OOE-Ol 3.02E-Ol 1.60E-Ol O.OOE+OO 1. 52E-Ol 6.14E-Ol 

5.00E-Ol 3.16E-Ol 1.43E-Ol O.OOE+OO 1. 48E-Ol 6.06E-Ol 

6.00E-Ol 3. 29E-Ol 1.27E-OI O.OOE+OO 1. 42E-Ol 5. 98E-Ol 

7.00E-Ol 3.40E-Ol 1.BE-Ol O.OOE+OO 1.36E-Ol 5. 89E-Ol 

8.00E-Ol 3.50E-Ol 1.OlE-OI O.OOE+OO 1. 29E-Ol 5.80E-Ol 

9.00E-Ol 3. 59E-Ol 8. 96E-02 O.OOE+OO 1. 22E-Ol 5.70E-Ol 

1.00E+OO 3. 67E-Ol 7. 97E-02 O.OOE+OO 1. 15E-Ol 5.6lE-OI 

2.00E+OO 4.l2E-Ol 2. 42E-02 O.OOE+OO 5.24E-02 4. 89E-Ol 

3.00E+OO 4. 26E-Ol 7.BE-03 O.OOE+OO 2.09E-02 4. 54E-Ol 

4.OOE+OO 4.31E-Ol 2.05E-03 O.OOE+OO 7.95E-03 4.4lE-Ol 

5.00E+OO 4. 32E-Ol 5.80E-04 O.OOE+OO 2. 96E-03 4. 35E-Ol 

6.00E+OO 4. 32E-Ol 1.62E-04 O.OOE+OO 1.lOE-03 4. 33E-Ol 

7.00E+OO 4. 32E-Ol 4. 47E-05 O.OOE+OO 4.04E-04 4. 32E-Ol 

8.00E+OO 4. 32E-Ol 1.22E-05 O.OOE+OO 1.49E-04 4. 32E-Ol 

9.00E+OO 4. 32E-Ol 3. 32E-06 O.OOE+OO 5. 48E-05 4. 32E-Ol 

1.OOE+Ol 4.32E-Ol 8.96E-07 O.OOE+OO 2.02E-05 4. 32E-Ol 

2.00E+Ol 4.31E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.31E-Ol 

3.00E+Ol 4.31E-0l O.OOE+OO O.OOE+OO O.OOE+OO 4.31E-O 

4.OOE+Ol 4.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.30E-O 

5.00E+Ol 4.30E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.30E-O 

6.00E+Ol 4. 29E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 29E-Ol 

7.00E+Ol 4. 29E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 29E-Ol 

8. OOE+O 1 4. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 28E-Ol 

9.00E+Ol 4. 28E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 28E-Ol 

1.OOE+02 4. 27E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-Ol 

2.00E+02 4. 22E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4. 22E-Ol 

3.00E+02 4.l7E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.17E-Ol 

4.OOE+02 4. fiE-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.12E-Ol 

5.00E+02. 4.07E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.07E-Ol 

6.00E+02 4.02E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.02E.-Ol 

7.00E+02 3. 98E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 98E-Ol 

8.00E+02 3. 93E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 93E-Ol 

.. 9.00E+02 3. 88E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 88E-Ol 

'; .'.; . 

.. 

:., , 1.OOE+03 3. 83E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 3.83E-Ol 

2.00E+03 3.40E-Ol O.OOE+OO O.OO~+OO O.OOE+OO 3.40E-Ol 

4.OOE+03 2. 68E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.68E-Ol 

8.00E+03 1. 66E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.66E-Ol 

1.OOE+04 1.31E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.31E-0l 

2.00E+04 4.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.05E-02 

B-156 
ClASS D AMAD - 1 HICKOK BALFLlPE-7.9SE+03 DAYS ACTDlIUM 227 

TI~ AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 5. 18E-03 6.07E-05 

2.00E-Ol 1.04E-02 7. 42E-04 

3:00E-0l 1.50E-02 2. 64E-03 

4.00E-Ol 1. 89E-02 5. 93E-03 

5.00E-Ol 2. 23E-02 1.05E-02 

6.00E-Ol 2. 52E-02 1. 61E-02 

7.00E-Ol 2.78E-02 2. 25E-02 

8.00E-Ol 3.01E-02 2. 94E-02 

9.00E-Ol 3. 21E-02 3. 66E-02 

1.00E+00 3. 39E-02 3. 39E-02 4.40E-02 4.40E-02 

2.00E+00 9.72E-03 4. 36E-02 6. 24E-02 1.06E-Ol 

3.00E+00 2. 99E-03 4. 66E-02 3. 15E-02 1. 38E-ol 

4.00E+00 9. 12E-04 4.75E-02 1.30E-02 1.51E-Ol 

5.00E+00 2. 79E-04 4. 78E-02 4. 98E-03 1. 56E-ol 

6.00E+00 9.05E-05 4. 79E-02 1.87E-03 1.58E-Ol 

7.00E+00 3. 59E-05 4. 79E-02 6. 92E-04 1. 58E-Ol 

8.00E+00 2.04E-05 4. 79E-02 2.55E-04 1. 59E-Ol 

9.00E+00 1.60E-05 4. 79E-02 9.41E-05 1. 59E-Ol 

1.00E+Ol 1.48E-05 4.80E-02 3. 46E-05 1. 59E-Ol 

2.00E+Ol 1.43E-05 4. 81E-02 O.OOE+OO 1. 59E-Ol 

3.00E+Ol 1. 43E-05 4. 82E-02 O.OOE+oo 1.58E-Ol 

4.00E+Ol 1. 43E-05 4. 83E-02 O.OOE+OO 1. 58E-ol 

5.00E+Ol 1. 43E-05 4. 84E-02 O.OOE+oo 1. 58E-Ol 

6.00E+Ol 1. 43E-05 4. 85E-02 O.OOE+OO 1.58E-Ol 

7.00E+Ol 1.42E-05 4. 86E-02 O.OOE+OO 1. 58E-Ol 

8.00E+Ol 1.42E-05 4. 87E-02 O.OOE+OO 1. 58E-Ol 

9.00E+Ol 1. 42E-05 4. 88E-02 O.OOE+OO 1.58E-Ol 

1.00E+02 1.42E-05 4. 89E-02 O.OOE+OO 1. 57E-Ol 

2.00E+02 1.40E-05 4. 98E-02 O.OOE+oo 1. 56E-Ol 

3.00E+02 1. 38E-05 5.08E-02 O.OOE+OO 1. 55E-Ol 

4.00E+02 1. 37E-05 5. 17E-02 O.OOE+oo 1. 53E-0l 

5.00E+02 1. 35E-05 5. 26E-02 O.OOE+OO 1. 52E-Ol 

7.00E+02 1.31E-05 5. 44E-02 O.OOE+oo 1.49E-Ol 

8.00E+02 1.30E-05 5. 52E-02 O.OOE+OO 1. 48E-Ol 

9.00E+02 1. 28E-05 5.60E-02 O.OOE+oo 1. 47E-Ol "," , " 1.00E+03 1. 27E-05 5.68E-02 O.OOE+OO 1. 46E-Ol 

2.00E+03 1. 12E-05 6.34E-02 O.OOE+OO 1. 33E-Ol 

3.00E+03 9. 83E-06 6. 81E-02 O.OOE+OO 1. 22E-Ol 

4.00E+03 8. 67E-06 7.13E-02 O.OOE+OO 1. 12E-Ol 

5.00E+03 7. 65E-06 7. 31E-02 O.ooE+OO 1.03E-Ol 

7.00E+03 5. 95E-06 7. 38E-02 O.OOE+oo 8.63E-02 

8.00E+03 5. 25E-06 7.30E-02 O.OOE+OO 7. 91E-02 

9.00E+03 4. 63E-06 7. 16E-02 O.OOE+oo 7. 25E-02 

1.00E+04 4.09E-06 6. 98E-02 O.OOE+OO 6. 64E-02 

2.00E+04 1. 19E-06 4.35E-02 O.OOE+OO 2. 78E-02 

B-157 
CLASS D .AMAD - 1 HICR.OR BALPLIFE- S.79E+07 DAYS UBARIUH 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 2.3SE-01 2. 26E-01 3.03E-04 1. S4E-0l 6.1SE-01 

2.00E-01 2.3SE-01 2.01E-Ol 2. 96E-07 1.S2E-01 S.88E-01 

3.00E-01 2.3SE-0l 1. 79E-01 O.OOE+OO 1. 49E-01 S.63E-01 

4.00E-01 2. 33E-01 1.60E-01 O.OOE+OO 1.4SE-01 S.38E-01 

S.OOE-01 2. 31E-0l 1. 43E-01 O.OOE+OO 1.41E-0l 5.1SE-01 

6.00E-01 2.30E-01 1.27E-01 O.OOE+OO 1.3SE-0l 4. 92E-01 

7.00E-01 2. 28E-0l 1. 13E-0l O.OOE+OO 1.29E-01 4.70E-01 

8.00E-01 2. 26E-01 1.01E-01 O.OOE+OO 1. 22E-01 4.49E-01 

9.00E-01 2. 24E-01 8. 96E-02 O.OOE+OO 1. 16E-0l 4. 29E-01 

1.00E+OO 2.22E-01 7. 97E-02 O.OOE+OO 1.09E-01 4.10E-01 

2.00E+OO 2.05E-01 2. 42E-02 O.OOE+OO 4.9SE-02 2. 78E-01 

3.00E+OO 1.90E-01 7.13E-03 O.OOE+OO 1. 97E-02 2. 16E-0l 

4.00E+OO 1.76E-0l 2.05E-03 O.OOE+OO 7.49E-03 1.86E-01 

5.00E+OO 1. 65E-01 5. 81E-04 O.OOE+OO 2. 79E-03 1. 68E-01 

6.00E+OO 1.S4E-01 1. 62E-04 O.O'OE+OO 1.03E-03 1.SSE-0l 

7.00E+OO 1.4SE-0l 4. 47E-OS O.OOE+OO 3. 81E-04 1.45E-01 

8.00E+OO 1. 36E-0l 1. 22E-OS O.OOE+OO 1.40E-04 1. 36E-01 

9.00E+OO 1. 28E-01 3. 32E-06 O.OOE+OO S.16E-OS 1.28E-01 

1.00E+01 1.21E-0l 8.96E-07 O.OOE+OO 1.90E-OS 1.21E-01 

2.00E+01 7. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 36E-02 

3.00E+01 S.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.06E-02 

4.00E+01 3.77E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 77E-02 

S.OOE+01 2. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 96E-02 

6.00E+01 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

7.00E+01 2.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.04E-02 

8.00E+01 1. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.78E-02 

9.00E+01 1.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-02 

1.00E+02 1.47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.47E-02 

2.00E+02 1.lSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.1SE-02 

3.00E+02 1. 12E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 12E-02 

4.00E+02 1.10E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.lOE-02 

S.OOE+02 1.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-02 

6.00E+02 1.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-02 

7.00E+02 1.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.06E-02 

8.00E+02 1.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-02 

9.00E+02 1.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-02 

1.OOE+03 1.01E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OlE-02 

2.00E+03 8. 11E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.11E-03 

4.00E+03 6. 53E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.S3E-03 

8.00E+03 3. 72E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 72E-03 

1.OOE+04 2.81E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.81E-03 

2.00E+04 7.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7.02E-04 

B-1S8 
CLASS D AMAD = 1 MICRON HALFLlFE- 5. 79E+07 DAYS URANIUM 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 2.41E-02 6.04E-05 

2.00E-Ol S.OOE-02 7. 33E-04 

3.00E-Ol 7.36E-02 2.60E-03 

4.00E-Ol 9.S0E-02 5.81E-03 

5.00E-Ol 1.14E-Ol 1.02E-02 

6.00E-Ol 1. 32E--Ol 1.S6E-02 

7.00E-Ol 1.48E-Ol 2.18E-02 

8.00E-Ol 1. 62E-Ol 2. 84E-02 

9.00E-Ol 1.7SE-Ol 3.S4E-02 

1.OOE+OO 1.87E-Ol 1. 87E-Ol 4. 24E-02 4. 24E-02 

2.00E+OO 7. 27E-02 2.59E-Ol S.92E-02 1.02E-Ol 

3.00E+OO 3.21E-02 2.91E-0l 2. 98E-02 1.31E-Ol 

4.00E+OO 1. 82E-02 3.lOE-Ol 1.22E-02 1. 44E-0l 

5.00E+OO 1.31E-02 3. 23E-Ol 4.70E-03 1. 48E-Ol 

6.00E+OO 1.09E-02 3. 34E-Ol 1.76E-03 1. SOE-Ol 

7.00E+OO 9. 64E-03 3. 43E-Ol 6. 52E-04 1.51E-Ol 

8.00E+OO 8.71E-03 3. 52E-Ol 2.41E-04 1.5lE-Ol 

9.00E+OO 7. 94E-03 3.60E-Ol 8. 87E-05 1.51E-Ol 

1.OOE+Ol 7. 26E-03 3. 67E-Ol 3. 26E-05 1.SlE-Ol 

2.00E+Ol 3. 26E-Ol 4.14E-Ol O.OOE+OO 1.51E-Ol 

3.00E+Ol 1.71E-03 4. 37E-Ol O.OOE+OO 1.51E-Ol 

4.00E+Ol 1.03E-:-03 4.50E-Ol O.OOE+OO 1.51E-Ol 

5.00E+Ol 6. 67E-04 4. 59E-Ol O.OOE+OO 1.51E-Ol 

6.00E+Ol 4. 54E-04 4. 64E-Ol O.OOE+OO 1.51E-Ol 

7.00E+Ol 3.16E-04 4.68E-0l O.OOE+OO 1. SlE-Ol 

8.00E+Ol 2. 22E-04 4.70E-Ol O.OOE+OO 1.51E-ol 

9.00E+Ol 1.57E-04 4.72E-Ol O.OOE+OO 1.51E-0l 

1.OOE+02 1.llE-04 4. 73E-Ol O.OOE+OO 1.SlE-Ol 

2.00E+02 S.lSE-06 4. 77E-Ol O.OOE+OO 1.51E-Ol 

3.00E+02 1.80E-06 4. 77E-Ol O.OOE+OO 1.SlE-Ol 

4.00E+02 1.67E-06 4.77E-Ol O.OOE+OO 1.SlE-Ol 

S.OOE+02 1. 64E-06 4. 77E-Ol O.OOE+OO 1.51E-0l 

6.00E+02 1.61E-06 4.77E-Ol O.OOE+OO 1.51E-Ol 

7.00E+02 1.S8E-06 4. 78E-Ol O.OOE+OO 1.SlE-Ol 

8.00E+02 1.S6E-06 4.78E-Ol O.OOE+OO 1.5lE-0l 

9.00E+02 1.S3E-06 4. 78E-Ol O.OOE+OO 1.SlE-Ol 

1.OOE+03 1.50E....;06 4. 78E-Ol O.OOE+OO 1.SlE-Ol 

2.00E+03 1.27E-06 4. 79E-Ol O.OOE+OO 1.SlE-Ol 

4.00E+03 9.3SE-07 4. 82E-Ol O.OOE+OO 1.SlE-Ol 

8.00E+03 S.27E-07 4. 84E-Ol O.OOE+OO hSlE-Ol 

1.OOE+04 4.0lE-07 4.8SE-Ol O.OOE+OO 1. SlE-Ol 

2.00E+04 1.l7E-07 4. 87E-Ol O.OOE+OO l.SlE-Ol 

B-159 
CLASS D AHAD ... 1 MICRON HALFLIFE- 2.57E+l1 DAYS URANIUM· 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 2.35E-Ol 2. 26E-0l 3.03E-04 1. S4E-Ol 6.l5E-Ol 

2.00E-Ol 2.3SE-Ol 2.0lE-Ol 2. 96E-07 1.S2E-Ol S.88E-0l 

3.00E-Ol 2. 35E-0l 1.79E-Ol O.OOE+OO 1.49E-Ol S.63E-Ol 

4.00E-Ol 2.33E-Ol 1.60E-Ol O.OOE+OO 1.4SE-Ol S.38E-Ol 

5.00E-Ol 2.3lE-Ol 1. 43E-Ol O.OOE+OO 1.4lE-Ol S.15E-Ol 

6.00E-Ol 2.30E-Ol 1.27E-Ol O.OOE+OO 1.3SE-Ol 4. 92E-Ol 

7.00E-Ol 2.28E-Ol 1.13E-Ol O.OOE+OO 1.29E-Ol 4.70E-oi 

8.00E-Ol 2. 26E-Ol 1.OlE-Ol O.OOE+OO 1.22E-Ol 4. 49E-Ol 

9.00E-Ol 2. 24E-Ol 8.96E-02 O.OOE+OO 1.16E-Ol 4. 29E-Ol 

1.OOE+OO 2. 22E-Ol 7. 97E-02 O.OOE+OO 1.09E-ol 4.lOE-Ol 

2.00E+OO 2.0SE-0l 2. 42E-02 O.OOE+OO 4.9SE-02 2.78E-0l 

3.00E+OO 1.90E-0l 7.l3E-03 O.OOE+OO 1. 97E-02 2.l6E-Ol 

4.00E+OO 1.76E-Ol 2.0SE-03 O.OOE+OO 7. 49E-03 1. 86E-0l 

S.OOE+OO 1.6SE-Ol S.8lE-04 O.OOE+OO 2. 79E-03 1. 68E-Ol 

6.00E+OO 1. 54E-Ol 1.62E-04 O.OOE+OO 1.03E-03 1.5SE-0l 

7.00E+OO 1.4SE-Ol 4. 47E-OS O.OOE+OO 3.8lE-04 1.4SE-Ol 

8.00E+OO 1.36E-0l 1. 22E-OS O.OOE+OO 1.40E-04 1. 36E-Ol 

9.00E+OO 1. 28E-Ol 3. 32E-06 O.OOE+OO S.16E-05 1. 28E-Ol 

1.OOE+Ol 1.2lE-Ol 8. 96E-07 O.OOE+OO 1.90E-05 1.2lE-Ol 

2.00E+Ol 7. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 36E-02 

3.00E+Ol 5.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.06E-02 __________ ~~ OOE+O L~ ____ .l ... ..71E-02 ___ QLOOE+QQ.. __ Q~j)OE±.OQ ____ Q ... QOEtQ9 3.77E-02 

5.00E+Ol .2.96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 96E-02 

6.00E+Ol 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

7.00E+Ol 2.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.04E-02 

8.00E+Ol 1. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 78E-02 

9.00E+Ol 1.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-02 

1.OOE+02 1.47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 47E-02 

2.00E+02 1.15E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.lSE-02 

3.00E+02 1.12E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-02 

4.00E+02 1.lOE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.lOE-02 

S.OOE+02 1.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-02 

6.00E+02 1.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-02 

7.00E+02 1.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.06E-02 

8.00E+02 1.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-02 

9.00E+02 1.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-02 

1.OOE+03 1.OlE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OlE-02 

2.00E+03 8.71E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.7lE-03 

4.00E+03 6.S3E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 53E-03 

8.00E+03 3. 72E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 72E-03 

1.OOE+04 2.81E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.81E-03 

2.00E+04 7.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7.02E-04 

B-160 
CLASS D MAD - 1 KICRON BALPLlPE- 2.57£+11 DAYS URANIUH 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.4lE-02 6.04E-05 

2.00E-Ol 5.00E-02 7. 33E-04 

3.00E-Ol 7. 36E-02 2.60E-03 

4.00E-Ol 9.50E-02 5.8lE-03 

5.00E-Ol 1.14E-Ol 1.02E-02 

6.00E-Ol 1. 32E-Ol 1. 56E-02 

7.00E-Ol 1. 48E-Ol 2.l8E-02 

8.00E-Ol 1. 62E-Ol 2. 84E-02 

9.00E-Ol 1.75E-Ol 3. 54E-02 

1.OOE+OO 1. 87E-Ol 1.87E-Ol 4. 24E-02 4. 24E-02 

2.00E+OO 7.27E-02 2. 59E-Ol 5. 92E-02 1.02E-Ol 

3.00E+OO 3.2lE-02 2.9lE-Ol 2. 98E-02 I.3lE-Ol 

4.00E+OO 1. 82E-02 3.l0E-Ol 1. 22E-02 1. 44E-Ol 

5.00E+OO 1.3lE-02 3.23E-Ol 4.70E-03 1.48E-Ol 

6.00E+OO 1.09E-02 3. 34E-Ol 1.76E-03 I.50E-Ol 

7.00E+OO 9. 64E-03 3.43E-Ol 6. 52E-04 1.5lE-Ol 

8.00E+OO 8.71E-03 3. 52E-Ol 2.4lE-04 I.5lE-0l 

9.00E+OO 7. 94E-03 3.60E-OI 8. 87E-05 I.5lE-Ol 

1.OOE+Ol 7. 26E-03 3. 67E-Ol 3. 26E-05 1.5lE-Ol 

2.00E+Ol 3. 26E-03 4.l4E-Ol O.OOE+OO 1.5lE-Ol 

3.00E+Ol 1.71E-03 4. 37E-Ol O.OOE+OO 1.5lE-Ol 

4.00E+Ol 1.03E-03 4.50E-Ol O.OOE+OO 1.5lE-Ol 

5.00E+Ol 6. 67E-04 4.59E-Ol O.OOE+OO 1.5lE-Ol 

6.00E+Ol 4. 54E-04 4. 64E-OI O.OOE+OO 1.5lE-Ol 

7.00E+Ol 3.l6E-04 4.68E-Ol O.OOE+OO 1.5lE-Ol 

8.00E+Ol 2. 22E-04 4.70E-Ol O.OOE+OO I.5lE-Ol 

9.00E+Ol 1.57E-04 4.72E-Ol O.OOE+OO 1.5lE-Ol 

1.OOE+02 1.llE-04 4. 73E-Ol O.OOE+OO I.5lE-Ol 

2.00E+02 5.l5E-06 4. 77E-Ol O.OOE+OO I.5lE-Ol 

3.00E+02 1.80E-06 4. 77E-Ol O.OOE+OO 1.5lE-OI 

4.00E+02 1. 67E-06 4.77E-Ol O.OOE+OO I.5IE-Ol 

5.00E+02 1. 64E-06 4.77E-Ol O.OOE+OO 1.5lE-Ol 

6.00E+02 1.6lE-06 4.77E-Ol O.OOE+OO 1.5lE-Ol 

7.00E+02 1. 58E-06 4. 78E-OI O.OOE+OO I.5lE-Ol 

8.00E+02 1. 56E-06 4. 78E-Ol O.OOE+OO 1.5IE-Ol 

9.00E+02 1. 53E-06 4. 78E-Ol O.OOE+OO 1.5lE-Ol 

1.OOE+03 1.50E-06 4. 78E-Ol O.OOE+OO 1.5lE-Ol 

2.00E+03 1. 27E-06 4. 79E-Ol O.OOE+OO 1.5lE-Ol 

4.00E+03 9. 35E-07 4. 82E-Ol O.OOE+OO 1.5lE-Ol 

8.00E+03 5. 27E-07 4. 84E-Ol O.OOE+OO 1.5lE-Ol 

1.OOE+04 4.0IE-07 4.85E-0l O.OOE+OO I.5lE-Ol 

2.00E+04 1.l7E-07 4.87E-Ol O.OOE+OO 1.5IE-Ol 

B-I6I 
CLASS D AMA.D - 1 MICRON BALl'LIFB= 1.16E+12 DAYS IJlWf.[UH 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 2. 33E-Ol 2.26E-Ol 3.03E-04 1. S4E-0l 6.1SE-0l 

2.00E-Ol 2.3SE-Ol 2.01E-o! 2. 96E-07 I.S2E-Ol S.88E-0l 

3.00E-0l 2.3SE-0l 1.79E-O! O.OOE+OO 1. 49E-OI S.63E-Ol 

4.00E-0l 2. 33E-Ol I.60E-O! O.OOE+OO 1.4SE-Ol S.38E-OI 

S.OOE-OI 2.31E-0l 1. 43E-O! O.OOE+OO 1. 41E-OI S.ISE-OI 

6.00E-OI 2.30E-Ol I.27E-OI O.OOE+OO I.3SE-Ol 4. 92E-Ol 

7.00E-0l 2.28E-Ol 1. 13E-0l O.OOE+OO 1. 29E-0l 4.70E-Ol 

8.00E-0l 2. 26E-Ol I.OIE-Ol O.OOE+OO 1. 22E-OI 4. 49E-Ol 

9.00E-0l 2. 24E-Ol 8. 96E-02 O.OOE+OO 1. 16E-0l 4. 29E-Ol 

1.00E+OO 2. 22E-Ol 7. 97E-02 O.OOE+OO I.09E-Ol 4.lOE-OI 

2.00E+OO 2.0SE-Ol 2.42E-02 O.OOE+OO 4.9SE-02 2. 78E-0l 

3.00E+OO 1.90E-Ol 7.13E-03 O.OOE+OO 1.97E-02 2. 16E-OI 

4.00E+OO 1. 76E-Ol 2.05E-03 O.OOE+OO 7.49E-03 1. 86E-Ol 

S.OOE+OO 1.6SE-Ol 5. 81E-04 O.OOE+OO 2. 79E-03 1. 68E-OI 

6.00E+OO 1. S4E-Ol 1.62E-04 O.OOE+OO 1.03E-03 I.5SE-Ol 

7.00E+OO 1.4SE-Ol 4. 47E-OS O.OOE+OO 3. 81E-04 1.4SE-Ol 

8.00E+OO 1. 36E-Ol 1. 22E-OS O.OOE+OO 1.40E-04 1. 36E-Ol 

9.00E+OO 1.28E-Ol 3. 32E-06 O.OOE+OO 5. 16E-05 1.28E-Ol 

1.00E+Ol 1.21E-Ol 8.96E-07 O.OOE+OO 1.90E-OS 1.21E-0l 

2.00E+Ol 7. 36E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 36E-02 

3.00E+OI S.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.06E-02 

4.00E+Ol 3. 77E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 77E-02 

5.00E+Ol 2. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.96E-02 

6.00E+Ol 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

7.00E+OI 2.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.04E-02 

8.00E+Ol 1. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 78E-02 

9.00E+Ol I.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-02 

1.00E+02 1.47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 47E-02 

2.00E+02 1.ISE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.ISE-02 

3.00E+02 1. 12E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 12E-02 

4.00E+02 1.10E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.10E-02 

5.00E+02 1.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-02 

6.00E+02 1.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.07E-02 

7.00E+02 1.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.06E-02 

8.00E+02 1.04E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-02 

9.00E+02 1.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-02 

1.00E+03 1.0IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OIE-02 ... 2.00E+03 8.11E-03 O.OOE+OO O.OOE+OO O.OOE+OO 8.11E-03 

4.00E+03 6.S3E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.S3E-03 

6.00E+03 4. 92E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 53E-03 

8.00E+03 3. 72E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.12E-03 

1.00E+04 2. 81E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.81E-03 

2.00E+04 7.02E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7.02E-04 

B-162 
CLASS D AIfA.D = 1 MICRON 1IALFLl1'E= 1.16E+12 DAYS IJIWUUK 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 2.41E-02 6.04E-05 

2.00E-Ol 5.00E-02 7. 33E-04 

3.00E-Ol 7. 36E-02 2.60E-03 

4.00E-Ol 9.50E-02 5.8lE-03 

S.OOE-Ol 1.14E-Ol 1.02E-02 

6.00E-Ol 1. 32E-Ol 1.S6E-02 

7.00E-Ol 1. 48E-0l 2.18E-02 

8.00E-Ol 1. 62E-Ol 2. 84E-02 

9.00E-Ol 1. 75E-Ol 3.S4E-02 

1.OOE+OO 1.87E-Ol 1. 87E-Ol 4. 24E-02 4. 24E-02 

2.00E+OO 7. 27E-02 2. 59E-Ol 5. 92E-02 1.02E-0l 

3.00E+OO 3.21E-02 2.91E-Ol 2. 98E-02 1.31E-Ol 

4.00E+OO 1. 82E-02 3.lOE-Ol 1.22E-02 1.44E-Ol 

5.00E+OO 1.31E-02 3. 23E-Ol 4.70E-03 1.48E-Ol 

6.00E+OO 1.09E-02 3.34E-Ol 1.76E-03 1.50E-0l 

7.00E+OO 9. 64E-03 3.43E-Ol 6. 52E-04 1.51E-ol 

8.00E+OO 8.71E-03 3.S2E-Ol 2.41E-04 1.51E-Ol 

9.00E+OO 7. 94E-03 3.60E-Ol 8. 87E-05 1.51E-Ol 

1.OOE+Ol 7. 26E-03 3. 67E-Ol 3. 26E-05 1.51E-Ol 

2.00E+Ol 3. 26E-03 4.14E-Ol O.OOE+OO 1.51E-Ol 

3.00E+Ol 1.71E-03 4. 37E-Ol O.OOE+OO 1.SlE-0l 

4.00E+Ol 1.03E-03 4.50E-Ol O.OOE+OO 1.51E-Ol 

5.00E+Ol 6. 67E-04 4. 59E-Ol O.OOE+OO 1.51E-Ol 

6.00E+OI 4. 54E-04 4. 64E-Ol O.OOE+OO 1.51E-Ol 

7.00E+Ol 3.16E-04 4. 68E-Ol O.OOE+OO 1.51E-0l 

8.00E+Ol 2. 22E-04 4.70E-OI O.OOE+OO 1.51E-Ol 

9.00E+Ol 1. 57E-04 4.72E-Ol O.OOE+OO 1.SlE-OI 

1.OOE+02 1.llE-04 4. 73E-OI O.OOE+OO 1.51E-OI 

2.00E+02 5.1SE-06 4. 77E-Ol O.OOE+OO 1.SlE-Ol 

3.00E+02 1.80E-06 4. 77E-Ol O.OOE+OO 1.5IE-Ol 

4.00E+02 1. 67E-06 4. 77E-Ol O.OOE+OO 1.SlE-0l 

5.00E+02 1. 64E-06 4.77E-Ol O.OOE+OO 1.SIE-0l 

6.00E+02 1.6IE-06 4. 77E-Ol O.OOE+OO 1.SlE-Ol 

7.00E+02 1.S8E-06 4. 78E-Ol O.OOE+OO 1.5IE-Ol 

8.00E+02 I.S6E-06 4. 78E-OI O.OOE+OO 1.5IE-Ol 

9.00E+02 1. 53E-06 4. 78E-Ol O.OOE+OO 1.SIE-Ol ~"'. ' , 1.OOE+03 1.SOE-06 4. 78E-OI O.OOE+OO I.SlE-Ol 

2.00E+03 1. 27E-06 4. 79E-OI O.OOE+OO 1.51E-OI 

4.00E+03 9. 35E-07 4. 82E-OI O.OOE+OO 1.51E-Ol 

8.00E+03 S.27E-07 4. 84E-Ol O.OOE+OO 1.SlE-0l 

1.OOE+04 4.01E-07 4. 85E-Ol O.OOE+OO 1.5lE-0l 

2.00E+04 1.l7E-07 4. 87E-Ol O.OOE+OO 1.5IE-Ol 

B-163 


.,9T-g: 

S'lOSOlIaY '" SSVI:) iO 

NOIJ.nvmn: a"'IDHIS lIOo!l SNOIJ.:w&f HOIJ.3'8'!JX3 U1IY NOIJ.N3J.mI 1104 S3'1&:VJ. -, 

o 
CLASS W AHA» - 1 KICRON STABLE BERYLLIUK 9 

TIME' AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.50E-02 2. 76E-Ol 2. 35E-Ol 5.11E-02 6. 33E-Ol 

2.00E-Ol 5. 97E-02 2. 65E-Ol 1.97E-Ol 1.05E-Ol 6.27E-Ol 

3.00E-Ol 5.5SE-02 2. 56E-Ol 1.66E-Ol 1.45E-Ol 6.23E-Ol 

4.00E-Ol 5.2SE-02 2. 47E-Ol 1.39E-Ol 1.7SE-Ol 6.lSE-Ol 

5.00E-Ol 5.05E-02 2.40E-Ol 1.17E-0l 2.05E-Ol 6.12E-Ol 

6.00E-Ol 4.S9E-02 2. 33E-Ol 9.S6E-02 2. 26E-Ol 6.06E-Ol 

7.00E-Ol 4. 76E-02 2. 27E-Ol S.29E-02 2. 42E-Ol 5. 99E-Ol 

S.OOE-Ol 4. 66E-02 2.2lE-Ol 6. 97E-02 2. 53E-Ol 5.90E-Ol 

9.00E-Ol 4. 59E-02 2.l6E-Ol 5.S6E-02 2.60E-Ol 5.S0E-Ol 

1.OOE+OO 4. 53E-02 2.llE-Ol 4. 93E-02 2. 64E-Ol 5.70E-Ol 

2.00E+OO 4. 35E-02 1.17E-Ol S.12E-03 2.02E-Ol 4. 32E-Ol 

3.00E+OO 4. 33E-02 1.60E-Ol 1. 54E-03 1.13E-Ol 3.17E-Ol 

4.00E+OO 4.3lE-02 1.50E-Ol 2.12E-04 5.69E-02 2.5lE-0l 

5.00E+OO 4. 29E-02 1.45E-Ol 4.S2E-05 2.S3E-02 2.l6E-Ol 

6.00E+OO 4.2SE-02 1.4lE-Ol S.5lE-06 1.46E-02 1.9SE-Ol 

7.00E+OO 4. 27E-02 1.3SE-Ol 1.5lE-06 S.09E-03 1.S9E-Ol 

S.OOE+OO 4. 25E-02 1.36E-Ol 2.66E-07 5.0lE-03 1.S3E-Ol 

9.00E+OO 4. 24E-02 1. 34E-Ol 4.70E-OS 3. 53E-03 1. SOE-Ol 

1.OOE+Ol 4. 23E-02 1.32E-Ol O.OOE+OO 2.S0E-03 .1.17E-Ol 

2.00E+Ol 4.lSE-02 1.16E-Ol O.OOE+OO 1. S6E-03 1.60E-Ol 

3.00E+Ol 4.lSE-02 1.02E-Ol O.OOE+OO 1.62E-03 1.46E-Ol 

4.00E+Ol 4. 23E-02 9.0lE-02 O.OOE+OO 1.4lE-03 1. 34E-Ol 

5.00E+Ol 4. 29E-02 7. 93E-02 O.OOE+OO 1.23E-03 1. 23E-Ol 

6.00E+Ol 4.36E-02 6.9SE-02 O.OOE+OO 1.07E-03 1.14E-Ol 

7.00E+Ol 4.42E-02 6.14E-02 O.OOE+OO 9.3lE-04 1.07E-Ol 

S.OOE+Ol 4. 49E-02 5.40E-02 O.OOE+OO S.llE-04 9. 97E-02 

9.00E+Ol 4. 55E-02 4. 75E-02 O.OOE+OO 7.06E-04 9. 37E-02 

1.OOE+02 4.60E-02 4.lSE-02 O.OOE+OO 6.15E-04 S.S4E-02 

2.00E+02 4. S3E-02 1.15E-02 O.OOE+OO 1. 54E-04 5. 99E-02 

3.00E+02 4. 75E-02 3.l5E-03 O.OOE+OO 3.S4E-05 5.07E-02 

4.00E+02 4.5SE-02 S.55E-04 O.OOE+OO 9.60E-06 4. 66E-02 

5.00E+02 4.3SE-02 2.3lE-04 O.OOE+OO 2.40E-06 4.40E-02 

6.00E+02 4.l9E-02 6.19E-05 O.OOE+OO 6.00E-07 4.l9E-02 

7.00E+02 4.00E-02 1. 65E-05 O.OOE+OO 1.50E-07 4.00E-02 

S.OOE+02 3.S2E-02 4.40E-06 O.OOE+OO 3.75E-OS 3.S2E-02 

9.00E+02 3. 65E-02 1.16E-06 O.OOE+OO O.OOE+OO 3. 65E-02 ~ ,".\' " 1.OOE+03 3.4SE-02 3.0SE-07 O.OOE+OO O.OOE+OO 3.4SE-02 

2.00E+03 2.l9E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.l9E-02 

4.00E+03 S.7lE-03 O.OOE+OO O.OOE+OO O.OOE+OO S.11E-03 

5.00E+03 5.49E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5. 49E-03 

7.00E+03 2.lSE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.lSE-03 

S.OOE+03 1.37E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 37E-03 

1.OOE+04 5.45E-04 O.OOE+OO O.OOE+OO O.OOE+OO 5. 45E-04 

2.00E+04 5. 36E-06 O.OOE+OO O.OOE+OO O.OOE+OO 5. 36E-06 

B-165 
ClASS W AKAD ... 1 KiCRON STABLE BERD.LIUH 9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAyS EXCRETA EXCRETA FECES FECES 

1.00E-01 6.03E-03 8.10E-06 

2.00E-Ol 1. 15E-02 1. 64E-04 

3.00E-Ol 1.57E-02 8. 28E-04 

4.00E-01 1. 89E-02 2. 42E-03 

5.00E-01 2. 14E-02 5. 27E-03 

6.00E-01 2. 33E-02 9. 59E-03 

7.00E-Ol 2. 48E-02 1. 55E-02 

8.00E-Ol 2.60E-02 2. 29E-02 

9.00E-01 2.69E-02 3. 18E-02 

1.00E+00 2. 76E-02 2. 76E-02 4.20E-02 4.20E-02 

2.00E+00 2.77E-03 3.04E-02 1. 35E-01 1.77E-01 

3.00E+00 9. 19E-04 3. 13E-02 1. 14E-01 2.90E-01 

4.00E+00 7. 32E-04 3.20E-02 6.61E-02 3. 57E-01 

5.00E+00 6. 87E-04 3. 27E-02 3.40E-02 3. 91E-01 

6.00E+00 6.60E-04 3. 33E-02 1.70E-02 4.08E-01 

7.00E+00 6. 39E-04 3.40E-02 8. 73E-03 4.l6E-01 

8.00E+00 6.20E-04 3. 46E-02 4. 81E-03 4.21E-01 

9.00E+00 6.03E-04 3. 52E-02 2. 95E-03 4. 24E-01 

1.00E+01 5. 86E-04 3. 58E-02 2.06E-03 4. 26E-Ol 

2.00E+01 4. 57E-04 4.09E-02 1.08E-03 4. 38E-01 

3.00E+Ol 3. 68E-04 4.50E-02 9.40E-04 4. 48E-01 

4.00E+Ol 3.05E-04 4. 83E-02 8. 18E-04 4. 57E-01 

5.00E+01 2. 59E-04 5. 11E-02 7.12E-04 4. 65E-01 

6.00E+Ol 2. 24E-04 5.34E-02 6.20E-04 4. 71E-01 

7.00E+Ol 1. 97E-04 5. 55E-02 5.40E-04 4.77E-01 

8.00E+Ol 1. 75E-04 5. 74E-02 4.70E-04 4. 82E-01 

9.00E+Ol 1. 57E-04 5.90E-02 4.09E-04 4. 86E-Ol 

1.00E+02 1. 42E-04 6.05E-02 3. 56E-04 4.90E-Ol 

2.00E+02 6.09E-05 6.99E-02 8.90E-05 5.09E-Ol 

3.00E+02 3. 39E-05 7.43E-02 2. 23E-05 5. 14E-Ol 

4.00E+02 2. 47E-05 7. 72E-02 5. 56E-06 5. 15E-01 

5.00E+02 2. 13E-05 7. 95E-02 1. 39E-06 5. 16E-01 

6.00E+02 1. 96E-05 8. 15E-02 3. 48E-07 5. 16E-Ol 

7.00E+02 1. 86E-05 8. 34E-02 8. 69E-08 5. 16E-01 

8.00E+02 1.77E-05 8.52E-02 2. 17E-08 5. 16E-01 

9.00E+02 1. 69E-05 8.70E-02 O.OOE+OO 5. 16E-Ol 

1.00E+03 1. 61E-05 8. 86E-02 O.OOE+OO 5. 16E-01 

2.00E+03 1.01E-05 1.01E-01 O.OOE+OO 5. 16E-01 

4.00E+03 4.02E-06 1. 15E-01 O.OOE+OO 5. 16E-Ol 

8.00E+03 6. 34E-07 1.22E-Ol O.OOE+OO 5. 16E-Ol 

1.00E+04 '2. 52E-07 1. 23E-01 O.OOE+OO 5. 16E-Ol 

B-166 
CLASS W .AHAD = 1 MICRON STABLE FLUORIBE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 1.07E-Ol 2.76E-Ol 2.3SE-Ol 2.lOE-02 6.39E-Ol 

2.00E-Ol 1.S7E-Ol 2.6SE-Ol 1.97E-Ol 1.96E-02 6. 39E-Ol 

3.00E-Ol 2.0lE-0l 2.S6E-Ol 1.66E-Ol 1.6SE-02 6. 39E-Ol 

4.00E-Ol 2.3SE-Ol 2. 47E-Ol 1. 39E-Ol 1. 43E-02 6. 39E-Ol 

S.OOE-Ol 2.70E-0l 2.40E-Ol 1.17E-Ol 1. 22E-02 6. 39E-Ol 

6.00E-Ol 2. 97E-Ol 2. 33E-Ol 9.S6E-02 1.OSE-02 6. 39E-Ol 

7.00E-Ol 3.2lE-Ol 2.27E-Ol S.29E-02 9.0lE-03 6.39E-Ol 

S.OOE-Ol 3.4lE-Ol 2.2lE-Ol 6. 97E-02 7.77E-03 6.39E-Ol 

9.00E-Ol 3.SSE-0l 2.l6E-Ol S.S6E-02 6.72E-03 6. 39E-Ol 

1.OOE+OO 3. 73E-Ol 2.llE-Ol 4. 93E-02 S.S3E-03 6. 39E-Ol 

2.00E+OO 4. SlE-Ol 1. 77E-Ol S.72E-03 1. 66E-03 6. 39E-Ol 

3.00E+OO 4. 77E-Ol 1.60E-Ol 1.S4E-03 6. 39E-04 6. 39E-Ol 

4.00E+OO 4.SSE-Ol 1.SOE-Ol 2.72E-04 3.0SE-04 6. 39E-Ol 

S.OOE+OO 4. 94E-Ol 1.4SE-Ol 4.S2E-OS 1. 74E-04 6.39E-Ol 

6.00E+OO 4 .. 9SE-Ol 1.4lE-Ol S.SlE-06 1.12E-04 6.39E-Ol 

7.00E+OO S.OlE-Ol 1.3SE-Ol 1. SlE-06 S.16E-OS 6. 39E-Ol 

S.OOE+OO S.03E-Ol 1.36E-0l 2. 66E-07 6.63E-OS 6.39E-Ol 

9.00E+OO S.OSE-Ol 1. 34E-Ol 4.70E-OS S.S3E-OS 6. 39E-Ol 

1.OOE+Ol S.07E-Ol 1.32E-Ol O.OOE+OO S.40E-OS 6. 39E-Ol 

2.00E+Ol S.23E-Ol 1.16E-Ol O.OOE+OO 4.3SE-OS 6. 39E-Ol 

3.00E+Ol S.37E-Ol 1.02E-Ol O.OOE+OO 3.S2E-OS 6. 39E-Ol 

4.00E+Ol S.49E-Ol 9.0lE-02 O.OOE+OO 3. 32E-OS 6. 39E-Ol 

S.OOE+Ol S.60E-Ol 7.93E-02 O.OOE+OO 2.S9E-OS 6.39E-Ol 

6.00E+Ol S.69E-Ol 6.9SE-02 O.OOE+OO 2.S2E-OS 6. 39E-Ol 

7.00E+Ol S.7SE-Ol 6.l4E-02 O.OOE+OO 2.l9E-OS 6. 39E-Ol 

S.OOE+Ol S.SSE-Ol S.40E-02 O.OOE+OO 1.9lE-OS 6. 39E-Ol 

9.00E+Ol S.92E-Ol 4.7SE-02 O.OOE+OO 1.66E-OS 6.39E-Ol 

1.OOE+02 S.97E-Ol 4.lSE-02 O.OOE+OO 1.4SE-OS 6.39E-Ol 

2.00E+02 6.2SE-Ol 1.lSE-02 O.OOE+OO 3.6lE-06 6. 39E-Ol 

3.00E+02 6. 36E-Ol 3.lSE-03 O.OOE+OO 9.04E-07 6. 39E-Ol 

4.00E+02 6.3SE-Ol S. SSE-04 O.OOE+OO 2. 26E-07 6.39E-Ol 

S.OOE+02 6.39E-Ol 2.3lE-04 O.OOE+OO S.6SE-OS 6.39E-Ol 

6.00E+02 6.39E-Ol 6.l9E-OS O.OOE+OO 1.4lE-OS 6.39E-Ol 

7.00E+02 6. 39E-Ol 1.6SE-OS O.OOE+OO O.OOE+OO 6.39E-Ol 

S.OOE+02 6.39E-Ol 4.40E""06 O.OOE+OO O.OOE+OO 6. 39E-Ol 

9.00E+02 6.39E-Ol 1.16E-06 O.OOE+OO O.OOE+OO 6.39E-Ol 

1.OOE+03 6. 39E-Ol 3.0SE-07 O.OOE+OO O.OOE+OO 6.39E-Ol 

2.00E+03 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

4.00E+03 6.39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

S.OOE+03 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

7.00E+03 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

S.OOE+03 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO· 6. 39E-Ol 

1.OOE+04 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 39E-Ol 

2.00E+04 6. 39E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 6.39E-Ol 

B-167 
CLASS W AHAD = 1 MICRON STABLE MAGNESIUM 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 7. 42E-02 2. 76E-Ol 2. 35E-Ol 5.0BE-02 6. 36E-Ol 

2.00E-Ol B.95E-02 2. 65E-Ol 1. 97E-Ol B.03E-02 6.3.2E-Ol 

3.00E-Ol 1.OBE-Ol 2. 56E-Ol 1.66E-Ol 9.B9E-02 6.2BE-Ol 

4.00E-Ol 1.24E-Ol 2. 47E-Ol 1. 39E-Ol 1.12E-Ol 6. 23E-Ol 

5.00E-Ol 1. 39E-Ol 2.40E-Ol 1.17E-Ol 1.22E-Ol 6.l7E-Ol 

6.00E-Ol 1.50E-Ol 2. 33E-Ol 9.B6E-02 1. 29E-Ol 6.llE-Ol 

7.00E-Ol 1.60E-Ol 2.27E-Ol B.29E-02 1.34E-Ol 6.04E-Ol 

B.OOE-Ol 1.6BE-Ol 2.2lE-Ol 6. 97E-02 1. 37E-Ol 5. 96E-Ol 

9.00E-Ol 1. 75E-Ol 2.l6E-Ol 5. 86E-02 1.3BE-Ol 5. 88E-Ol 

1.OOE+OO 1.8lE-Ol 2.llE-Ol 4. 93E-02 1.3BE-Ol 5. 79E-Ol 

2.00E+OO 2.09E-Ol 1.77E-Ol 8.72E-03 9. 86E-02 4. 93E-Ol 

3.00E+OO 2. 17E-Ol 1.60E-Ol 1. 54E-03 5.3BE-02 4. 32E-Ol 

4.00E+OO 2.20E-Ol 1.50E-Ol 2. 72E-04 2.70E-02 3. 97E-Ol 

5.00E+OO 2.2lE-Ol 1. 45E-Ol 4.B2E-05 1. 35E-02 3. 79E-Ol 

6.00E+OO 2.2lE-Ol 1.4lE-0l B.5lE-06 6.9BE-03 3.69E-Ol 

7.00E+OO 2.2lE-Ol 1.3BE-Ol 1.5lE-06 3. 92E-03 3. 63E-Ol 

8.00E+OO 2.20E-Ol 1.36E-Ol 2. 66E-07 2.46E-03 3. 58E-Ol 

9.00E+OO 2.20E-Ol 1. 34E-Ol 4.70E-OB 1. 76E-03 3.55E-Ol 

1.OOE+Ol 2.l9E-ol 1.32E-0l O.OOE+OO 1.4lE-03 3. 52E-Ol 

2.00E+Ol 2.l2E-Ol 1.16E-Ol O.OOE+OO 9. 57E-04 3. 29E-Ol 

3.00E+Ol 2.05E-Ol 1.02E-Ol O.OOE+OO B.33E-04 3.08E-Ol 

4.00E+Ol 1. 97E-Ol 9.0lE-02 O.OOE+OO 7. 25E-04 2.BBE-O 

5.00E+Ol 1.90E-Ol 7. 93E-02 O.OOE+OO 6.3lE-04 2. 69E-Ol 

6.00E+Ol 1.B2E-0l 6.9BE-02 O.OOE+OO 5.50E-04 2. 52E-Ol 

7.00E+Ol 1. 74E-Ol 6.l4E-02 O.OOE+OO 4.7BE-04 2. 36E-Ol 

8.00E+Ol 1. 66E-Ol 5.40E-02 O.OOE+OO 4.17E-04 2.20E-Ol 

9.00E+Ol 1. 58E-Ol 4.75E-02 O.OOE+OO 3.63E-04 2.06E-Ol 

1.OOE+02 1.5lE-Ol 4.lBE-02 O.OOE+OO 3.l6E-04 1. 93E-Ol 

2.00E+02 B.66E-02 1.15E-02 O.OOE+OO 7.B9E-05 9.B2E-02 

3.00E+02 4. 65E-02 3.l5E-03 O.OOE+OO 1. 97E-05 4. 97E-02 

4.00E+02 2. 42E-02 8.55E-04 O.OOE+OO 4. 93E-Q6 2.5lE-02 

5.00E+02 1. 24E-02 2.3lE-04 O.OOE+OO 1. 23E-06 1.26E-02 

6.00E+02 6. 25E-03 6.l9E-05 O.OOE+OO 3.0BE-07 6.3lE-03 

7.00E+02 3.l4E-03 1. 65E-05 O.OOE+OO 7.71E-OB 3.l6E-03 

B.OOE+02 1. 58E-03 4.40E-06 O.OOE+OO 1. 93E-OB 1.58E-03 

9.00E+02 7.90E-04 1.16E-06 O.OOE+OO O.OOE+OO 7.9lE-04 ;',.". 1.()OE+03 3.96E-04 3.0BE-07 O.OOE+OO O.OOE+OO 3.96E-04 

2.00E+03 3.B7E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3.B7E-07 

B-16B 
CLASS V AHA» = 1 MICRON STABLE MAGNESIUM 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.l2E-03 7. 37E-06 

2.00E-Ol 6.6lE-03 1. 37E-04 

3.00E-Ol 1.03E-02 6. 46E-04 

4.00E-Ol 1. 42E-02 1.7SE-03 

S.OOE-Ol 1. SOE-02 3.6SE-03 

6.00E-Ol 2.lSE-02 6. 43E-03 

7.00E-Ol 2.S4E-02 1.OOE-02 

S.OOE-Ol 2.SSE-02 1. 44E-02 

9.00E-Ol 3.19E-02 1.9SE-02 

1.OOE+OO 3.47E-02 3. 47E-02 2.S2E-02 2.S2E-02 

2.00E+OO 1.66E-02 S.13E-02 6.94E-02 9. 46E-02 

3.00E+OO 6.20E-03 S.7SE-02 S.S2E-02 1.50E-Ol 

4.00E+OO 3. 29E-03 6.0SE-02 3.14E-02 1.SlE-Ol 

5.00E+OO 2.40E-03 6.32E-02 1.60E-02 1.97E-01 

6.00E+OO 2.0SE-03 6.S2E-02 S.02E-03 2.05E-Ol 

7.00E+OO 1.90E-03 6.71E-02 4. 14E-03 2.09E-01 

S.OOE+OO 1.S2E-03 6.S9E-02 2.30E-03 2. 12E-01 

9.00E+OO 1.7SE-03 7.07E-02 1. 43E-03 2.13E-01 

1.00E+01 1.7SE-03 7.2SE-02 1.01E-03 2.l4E"-Ol 

2.00E+Ol 1. 67E-03 S.9SE-02 5. 42E-04 2.20E-Ol 

3.00E+Ol 1.S9E-03 1.06E-Ol 4.72E-04 2.2SE-Ol 

4.00E+Ol 1.S2E-03 1.2lE-Ol I 4.llE-04 2.30E-Ol 

S.OOE+01 1.4SE-03 1. 36E-Ol 3. S7E-04 2. 34E-01 

6.00E+01 1.3SE-03 1.50E-Ol 3.llE-04 2. 37E-Ol 

7.00E+01 1.31E-03 1.64E-Ol 2.71E-04 2.40E-Ol 

S.OOE+Ol 1.2SE-03 1. 76E-01 2. 36E-04 2.42E-01 

9.00E+Ol 1.lSE-03 1.S9E-Ol 2.05E-04 2. 44E-01 

1.00E+02 1.12E-03 2.00E-Ol 1.79E-04 2. 46E-Ol 

2.00E+02 6. 23E-04 2. SSE-Ol 4. 47E-05 2.56E-Ol 

3.00E+02 3.30E-04 3.3lE-Ol 1.12E-OS 2.SSE-Ol 

4.00E+02 1.70E-04 3.SSE-Ol 2.79E-06 2.S9E-Ol 

5.00E+02 S.64E-05 3. 67E-01 6.9SE-07 2. 59E-01 

6.00E+02 4. 36E-05 3. 74E-Ol 1.75E-07 2. 59E-01 

.. ., 7.00E+02 2.l9E-OS 3. 77E-01 4. 36E-OS 2. S9E-Ol . ' .-~ :. ~ '_ .' .. , '., I S.OOE+02 1.lOE-OS 3.7SE-Ol 1.09E-OS 2.S9E-01 

9.00E+02 S.50E-06 3. 79E-Ol O.OOE+OO 2. S9E-Ol 

1.00E+03 2.75E-06 3.S0E-Ol O.OOE+OO 2. 59E-Ol 

B-169 
CLASS W AHA.D = 1 KICB.OH STABLE ALUHI.NUH 27 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7.lOE-02 2.76E-Ol 2.3SE-Ol S.71E-02 6. 39E-Ol 

2.00E-Ol 7.13E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 39E-Ol 

3.00E-Ol 7.l7E-02 2.S6E-Ol 1. 66E-Ol 1.4SE-0l 6.3SE-Ol 

4. OOE-O1 7.2lE-02 2. 47E-Ol 1. 39E-Ol 1.7SE-Ol 6. 37E-Ol 

S.OOE-Ol 7. 24E-02 2.40E-Ol 1.17E-Ol 2.04E-Ol 6. 34E-Ol 

6.00E-Ol 7.2SE-02 2. 33E-Ol 9.S6E-02 2.2SE-Ol 6. 29E-Ol 

7.00E-Ol 7.3lE-02 2. 27E-Ol S.29E-02 2.4lE-Ol 6.23E-Ol 

8.00E-Ol 7. 33E-02 2.2lE-Ol 6. 97E-02 2.s2E-Ol 6.l6E-Ol 

9.00E-Ol 7.3sE-02 2.l6E-Ol S.S6E-02 2. S9E-Ol 6.07E-Ol 

1.OOE+OO 7. 37E-02 2.llE-Ol 4. 93E-02 2. 63E-Ol S.97E-Ol 

2.00E+OO 7. 47E-02 1. 77E-0l S.72E-03 2.0lE-Ol 4. 62E-Ol 

3.00E+OO 7.S0E-02 1.60E-Ol 1.S4E-03 1.12E-Ol 3.4SE-Ol 

4.00E+OO 7.SlE-02 1.sOE-Ol 2. 72E-04 s.66E-02 2.S2E-Ol 

S.OOE+OO 7.S2E-02 1.4sE-01 4.S2E-oS 2. 82E-02 2.4SE-Ol 

6.00E+OO 7.S2E-02 1.4lE-Ol 8.SlE-06 1.4SE-02 2.3lE-Ol 

7.00E+OO 7.S2E-02 1.3SE-01 1.slE-06 8.0SE-03 2.2lE-01 

8.00E+OO 7.SlE-02 1.36E-01 2.66E-07 4. 99E-03 2.l6E-Ol 

9.00E+00 7.SlE-02 1. 34E-Ol 4.70E-08 3.SlE-03 2.l3E-Ol 

1.OOE+Ol 7.SlE-02 1. 32E-Ol O.OOE+OO 2.79E-03 2.l0E-0l 

2.00E+Ol 7.4sE-02 1.16E-0l O.OOE+OO 1.8sE-03 1. 93E-Ol 

3.00E+Ol 7.36E-02 1.02E-Ol O.OOE+OO 1.6lE-03 1.7 

4.00E+Ol 7. 23E-02 9.0lE-02 O.OOE+OO 1.40E-03 1. 

s.OOE+Ol 7.0SE-02 7. 93E-02 O.OOE+OO 1.22E-03 1.51 

6.00E+Ol 6.90E-02 6.9SE-02 O.OOE+OO 1.06E-03 1.40E-Ol 

7.00E+Ol 6.7lE-02 6.l4E-02 O.OOE+OO 9.27E-04 1.29E-Ol 

8.00E+Ol 6.S0E-02 S.40E-02 O.OOE+OO 8.07E-04 1.20E-01 

9.00E+Ol 6. 29E-02 4.7sE-02 O.OOE+OO 7.02E-04 1.UE-01 

1.OOE+02 6.06E-02 4.l8E-02 O.OOE+OO 6.l2E-04 1.03E-Ol 

2.00E+02 3.S2E-02 1.lSE-02 O.OOE+OO 1. S3E-04 4. 99E-02 

3.00E+02 2. 16E-02 3.lSE-03 O.OOE+OO 3.S2E-Os 2.4SE-02 

4.00E+02 l.l6E"-02 8.SSE-04 O.OOE+OO 9.S6E-06 1. 24E-02 

S.OOE+02 6.02E-03 2. 31E-04 O.OOE+OO 2. 39E-06 6.2SE-03 

6.00E+02 3.07E-03 6.19E-OS O.OOE+OO S.97E-07 3.l4E-03 

7.00E+02 I.S6E-03 1.6SE-OS O.OOE+OO 1. 49E-07 1. S7E-03 

8.00E+02 7.S3E-04 4.40E-06 O.OOE+OO 3. 73E-08 7.87E-04 

9.00E+02 3. 93E-04 1. 16E-06 O.OOE+OO O.OOE+OO 3. 94E-04 ' ... , 1.00E+03 1.97E-04 3.0SE-07 O.OOE+OO O.OOE+OO 1. 97E-04 

2.00E+03' 1. 93E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1.93E-07 

B-170 
CLASS W AHAJ) - 1 HICR.ON STABLE ALUMINIUM 27 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 4.2IE-OS S.09E-06 

2.00E-ol 9.ISE-OS I. 64E-04 

3.00E-OI 1.4IE-04 S.27E-04 

4.00E-OI 1.9IE-04 2.4IE-03 

S.OOE-Ol 2.4IE-04 S.26E-03 

6.00E-OI 2.9IE-04 9. 57E-03 

7.00E-0l 3. 42E-04 I. 54E-02 

S.OOE-Ol 3. 92E-04 2. 29E-02 

9.00E-OI 4. 43E-04 3.17E"-02 

I.OOE+OO 4. 94E-04 4. 94E-04 4.19E-02 4.19E-02 

2.00E+OO S.ISE-04 I.OIE-03 I. 34E-OI I. 76E-OI 

3.00E+OO S.19E-04 I.S3E-03 1.13E-OI 2.S9E-OI 

4.00E+OO 5.20E-04 2.0SE-03 6.S7E-02 3. SSE-Ol 

S.OOE+OO S.2IE-04 2.S7E-03 3.3SE-02 3.S9E-OI 

6.00E+OO 5.2IE-04 3.09E-03 I. 69E-02 4.06E-OI 

7.00E+OO 5.2IE-04 3.6IE-03 S.6SE-03 4.14E-OI 

S.OOE+OO S.2IE-04 4.l3E-03 4.7SE-03 4.19E-0l 

9.00E+OO S.2IE-04 4.6SE-03 2. 93E-03 4. 22E-OI 

I.OOE+OI S.20E-04 S.17E-03 2.0SE-03 4. 24E-0l 

2.00E+OI S.17E-04 I.04E-02 I.07E-03 4. 36E-0l 

3.00E+OI S.IOE-04 I.SSE-02 9.3SE-04 4.46E-OI 

4.00E+OI 5.02E-04 2.0SE-02 8.14E-04 4.SSE-OI 

S.OOE+OI 4.9IE-04 2.SSE-02 7.0SE-04 4. 62E-OI 

6.00E+OI 4. 79E-04 3.04E-02 6.17E-04 4. 69E-OI 

7.00E+OI 4. 66E-04 3. SIE-02 S.37E-04 4.7SE-0l 

S.OOE+OI 4.SIE-04 3. 96E-02 4. 67E-04 4.S0E-OI 

9.00E+OI " 4.36E-04 4.4IE-02 4.07E-04 4.S4E-0l 

I.OOE+02 4.2IE-04 4.S4E-02 3.S4E-04 4.SSE-0l 

2.00E+02 2. 66E-04 S.24E-02 S.S6E-OS S.07E-OI 

3.00E+02 I.SOE-04 I.03E-Ol 2.2IE-OS 5.l2E-OI 

4.00E+02 S.OSE-OS 1.14E':""OI 5.S3E-06 S.l3E-OI 

S.OOE+02 4.ISE-OS 1.20E-OI 1.3SE-06 S.13E-OI 

6.00E+02 2.14E-OS 1';23E-OI 3. 46E-07 S.l3E-OI 

7.00E+02 I.OSE-OS 1.24E-OI S.65E-OS S.13E-OI ." ;. S.OOE+02 5. 44E-06 1.2SE-OI 2.l6E-OS S.13E-0l 

9.00E+02 2. 73E-06 1.26E-OI O.OOE+OO S.13E-OI 

I.OOE+03 I. 37E-06 I. 26E-OI O.OOE+OO S.l3E-OI 

B-171 
CLASS W AHAD - 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 7.07E-02 2.76E-Ol 2.35E-Ol 5.7lE-02 6. 39E-Ol 

2.00E-Ol 7.07E-02 2. 65E-Ol 1. 97E-Ol I.05E-OI 6.3BE-Ol 

3.00E-Ol 7.06E-02 2.56E-Ol 1.66E-Ol 1.45E-Ol 6.37E-Ol 

4.00E-Ol 7.07E-02 2. 47E-Ol 1. 39E-Ol 1.7BE-OI 6. 35E-Ol 

5.00E-Ol 7.07E-02 2.40E-Ol 1.l7E-OI 2.04E-Ol 6. 32E-Ol 

6.00E-Dl 7.06E-02 2. 33E-OI 9.B6E-02 2.25E-OI 6. 27E-Ol 

7.00E-OI 7.06E-02 2. 27E-Ol B.29E-02 2.4IE-OI 6.21E-OI 

B.OOE-Dl 7.05E-02 2.2IE-Ol 6. 97E-02 2. 52E-Ol 6. I 3E-O I 

9.00E-OI 7.04E-02 2.16E-Ol 5.B6E-02 2. 59E-Ol 6.04E-Ol 

I.OOE+OO 7.02E-02 2.llE-OI 4. 93E-02 2. 63E-OI 5. 93E-DI 

2.00E+OO 6. BOE-02 I.77E-Ol B.72E-03 2.0lE-Ol 4.55E-Ol 

3.00E+OO 6. 55E-02 1.60E-Ol 1. 54E-03 1.12E-Ol 3. 39E-Ol 

4.00E+OO 6.3lE-02 1.50E-OI 2.72E-04 5. 66E-02 2.70E-Ol 

5.00E+OO 6.10E-02 I. 45E-Ol 4.B2E-05 2.B2E-02 2. 34E-Ol 

6.00E+OO 5.9lE-02 1.4IE-0l B.51E-06 1. 45E-02 2.14E-Ol 

7.00E+OO 5. 75E-02 1.3BE-Ol 1.51E-06 B.05E-03 2.04E-OI 

B.OOE+OO 5.61E-02 1.36E-OI 2.66E-07 4. 99E-03 1.97E-OI 

9.00E+OO 5.4BE-02 1. 34E-Ol 4.70E-OB 3.5lE-03 I. 92E-Ol 

1.OOE+OI 5.37E-02 1. 32E-OI O.OOE+OO 2. 79E-03 1. 89E-Ol 

2.00E+Ol 4.7BE-02 I.16E-Ol O.OOE+OO 1.B5E-03 I. 66E-Ol 

3.00E+OI 4.5BE-02 1.02E-Ol O.OOE+OO I.6IE-03 1.50E-Dl 

4.00E+OI 4. 46E-02 9.0lE-02 O.OOE+OO 1.40E-03 1. 36E-Ol 

5.00E+Ol 4. 35E-02 7. 93E-02 O.OOE+OO 1. 22E-03 1.24E-Ol 

6.00E+Ol 4. 23E-02 6.9BE-02 O.OOE+OO 1.06E-03 1. 13E-Ol 

7.00E+Ol 4.llE-02 6.14E-02 O.OOE+OO 9. 27E-04 1.03E-Ol 

8.00E+Ol 3.9BE-02 5.40E-02 O.OOE+OO 8.07E-04 9. 46E-02 

9.00E+OI 3.B4E-02 4.75E-02 O.OOE+OO 7.02E-04 8. 66E-02 

1.OOE+02 3.70E-02 4.1BE-02 O.OOE+OO 6.12E-04 7. 94E-02 

2.00E+02 2.31E-02 1.I5E-02 O.OOE+OO 1. 53E-04 3.4BE-02 

3.00E+02 I.30E-02 3.15E-03 O.OOE+OO 3.B2E-05 I. 62E-02 

4.00E+02 6. 97E-03 B.55E-04 O.OOE+OO 9. 56E-06 7.B3E-03 

5.00E+02 3. 62E-03 2.3IE-04 O.OOE+OO 2. 39E-06 3.B5E-03 

6.00E+02 1.B5E-03 6.19E-05 O.OOE+OO 5. 97E-07 I.9IE-03 

7.00E+02 9. 34E-04 1. 65E-05 O.OOE+OO 1. 49E-07 9.50E-04 

B.OOE+02 4.70E-04 4.40E-06 O.OOE+OO 3. 73E-OB 4.74E-04 

9.00E+02 2. 36E-04 I.I6E-06 O.OOE+OO O.OOE+OO 2. 37E-04 

I.OOE+03 I.lBE-04 3.0BE-07 O.OOE+OO O.OOE+OO I.IBE-04 

2.00E+03 1.16E-07 O.OOE+OO O.OOE+OO O.OOE+OO I.16E-07 

B-l72 
ClASS V AHAD "" 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-ROUR ACCUMULATED 24-ROUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3. 61E-04 8.09E-06 

2.00E-Ol 7.80E-04 1. 64E-04 

3.00E-Ol 1.19E-03 8. 27E-04 

4.00E-Ol 1.61E-03 2.41E-03 

5.00E-Ol 2.02E-03 5. 26E-03 

6.00E-Ol 2. 42E-03 9. 57E-03 

7.00E-Ol 2. 83E-03 1. 54E-02 

8.00E-Ol 3. 23E-03 2. 29E-02 

9.00E-Ol 3. 62E-03 3. 17E-02 

1.00E+OO 4.02E-03 4.02E-03 4. 19E-02 4. 19E-02 

2.00E+OO 3.72E-03 7. 74E-03 1. 34E-Ol 1. 76E-Ol 

3.00E+OO 3. 34E-03 l.llE-02 1. 13E-Ol 2. 89E-Ol 

4. QOE+OO 2. 98E-03 1. 41E-02 6. 57E-02 3. 55E-Ol 

5.00E+OO 2. 67E-03 1. 67E-02 3. 38E-02 3. 89E-Ol 

6.00E+OO 2.39E-03 1.91E-02 1.69E-02 4.06E-Ol 

7.00E+OO 2. 15E-03 2. 13E-02 8. 68E-03 4. 14E-0l 

8.00E+OO 1.94E-03 2. 32E-02 4. 78E-03 4. 19E-Ol 

9.00E+OO 1. 75E-03 2.50E-02 2. 93E-03 4. 22E-Ol 

1.00E+Ol 1. 59E-03 2. 65E-02 2.05E-03 4.24E-Ol 

2.00E+Ol 7. 66E-04 3.70E-02 1.07E-03 4. 36E-Ol 

3.00E+Ol 5. 45E-04 4 .• 32E-02 9.35E-04 4. 46E-Ol 

4.00E+OI 4. 74E-04 4. 82E-02 ·8. 14E-04 4. 55E-Ol 

5.00E+0l 4.40E-04 5. 28E-02 7.08E-04 4. 62E-Ol 6~OOE+Ol 4. 16E-04 5.70E-02 6.I7E-04 4. 69E-OI 

7.00E+OI 3.95E-04 6. lIE-02 5. 37E-04 4. 75E-OI 

8.00E+OI 3. 75E-04 6.49E-02 4. 67E-04 4.80E-Ol 

9.00E+Ol 3. 55E-04 6. 86E-02 4.07E-04 4. 84E-Ol 

1.00E+02 3. 37E-04 7.20E-02 3. 54E-04 4. 88E-OI 

2.00E+02 I. 87E-04 9. 75E-02 8. 86E-05 5.07E-Ol 

3.00E+02 9. 88E-05 1.11E-OI 2. 21E-05 5. 12E-0l 

4.00E+02 5.09E-05 I. 19E-0l 5. 53E-06 5. 13E-Ol 

5.00E+02 2. 59E-05 1. 22E-Ol I. 38E-06 5. 13E-Ol 

6.00E+02 1.30E-05 1.24E-Ol 3. 46E-07 5. 13E-Ol 

7.00E+02 6 •. 55E-06 1.25E-Ol 8. 65E-08 5.I3E-Ol 

8.00E+02 3. 28E-06 1.26E-Ol 2. 16E-08 5. 13E-Ol 

9.00E+02 1. 64E-06 1.26E-Ol O.OOE+OO 5. 13E-Ol 

1.00E+03 8. 23E-0.7 1.26E-Ol O.OOE+OO 5. 13E-Ol 

B-173 
CLASS W AMAD = 1 MICRON STABLE PHOSPHORUS 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------~-------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 8. 68E-02 2. 76E-Ol 2.3SE-Ol 3. 96E-02 6. 37E-Ol 

2.00E-Ol 1. 22E-Ol 2.6SE-Ol 1. 97E-Ol 4. 96E-02 6.3SE-Ol 

3.00E-Ol 1.S6E-Ol 2.S6E-Ol 1.66E-Ol S.37E-02 6.31E-Ol 

4.00E-Ol 1. 83E-Ol 2. 47E-O 1 1. 39E-Ol S.64E-02 6. 27E-Ol 

S.OOE-Ol 2.06E-Ol 2.40E-Ol 1.17E-Ol S.84E-02 6.21E-Ol 

6.00E-Ol 2.2SE-Ol 2. 33E-Ol 9. 86E-02 S.96E-02 6.16E-Ol 

7.00E-Ol 2.40E-Ol 2.27E-Ol 8. 29E-02 6.02E-02 6.09E-Ol 

8.00E-Ol 2.S2E-Ol 2.21E-Ol 6. 97E-02 6.02E-02 6.03E-Ol 

9.00E-Ol 2. 62E-0l 2.16E-Ol S.86E-02 S.98E-02 S.96E-Ol 

1.OOE+OO 2.70E-Ol 2.UE-Ol 4. 93E-02 S.89E-02 5.89E-OI 

2.00E+OO 2. 98E-Ol 1.77E-Ol 8.72E-03 3.9SE-02 S.23E-OI 

3.00E+OO 2.9SE-Ol 1.60E-0l 1.S4E-03 2.12E-02 4. 77E-Ol 

4.00E+OO 2. 87E-Ol 1. SOE-Ol 2.72E-04 1.06E-02 4. 48E-OI 

S.OOE+OO 2. 79E-OI 1.4SE-Ol 4. 82E-OS S.30E-03 4. 29E-Ol 

6.00E+OO 2. 72E-OI 1.4IE-0l 8.SIE-06 2.77E-03 4.ISE-0l 

7.00E+OO 2.6SE-OI I. 38E-OI I.SIE-06 I.S7E-03 4.0SE-OI 

8.00E+OO 2.60E-Ol 1. 36E-OI 2.66E-07 I.OOE-03 3. 97E-OI 

9.00E+OO 2.SSE-OI I. 34E-Ol 4.70E-08 7. 29E-04 3. 89E-Ol 

I.OOE+OI 2. SOE-OI 1.32E-OI O.OOE+OO S.93E-04 3. 83E-OI 

2.00E+OI 2.18E-OI 1.16E-OI O.OOE+OO 4.09E-04 3.3SE-OI 

3.00E+OI 1. 98E-OI 1.02E-OI O.OOE+OO 3.S6E-04 3.01E-OI 

4.00E+OI 1. 84E-OI 9.0IE-02 O.OOE+OO 3.lOE-04 2.7SE-Ol 

S.OOE+OI 1. 74E-Ol 7. 93E-02 O.OOE+OO 2.70E-04 2.S4E-Ol 

6.00E+OI 1. 68E-Ol 6. 98E-02 O.OOE+OO 2.3SE-04 2. 38E-OI 

7.00E+OI 1.63E-OI 6.14E-02 O.OOE+OO 2.04E-04 2. 24E-OI 

8.00E+OI I.S9E-OI 5.40E-02 O.OOE+OO 1. 78E-04 2.14E-OI 

9.00E+OI 1.57E-0l 4.7SE-02 O.OOE+OO I.SSE-04 2.0SE-OI 

I.OOE+02 I.SSE-OI 4.18E-02 O.OOE+OO 1.3SE-04 1. 97E-Ol 

2.00E+02 1. 47E-0l 1.15E-02 O.OOE+OO 3. 37E-OS I.S9E-Ol 

3.00E+02 1.4IE-Ol 3.ISE-03 O.OOE+OO 8.43E-06 1. 44E-Ol 

4.00E+02 1.3SE-0l 8.5SE-04 O.OOE+OO 2.UE-06 I. 36E-Ol 

S.OOE+02 1.29E-Ol 2.3IE-04 O.OOE+OO S.27E-07 1.29E-Ol 

6.00E+02 1. 23E-Ol 6.19E-OS O.OOE+OO 1. 32E-07 1.23E-Ol 

7.00E+02 1.l7E-OI 1.6SE-OS O.OOE+OO 3. 29E-08 1. 1 7E-O 1 

8.00E+02 1.12E-0l 4.40E-06 O.OOE+OO O.OOE+OO 1.12E-0l 

9.00E+02 1.07E-Ol 1.16E-06 O.OOE+OO O.OOE+OO 1.07E-Ol 

I.OOE+03 I.02E-Ol 3.08E-07 O.OOE+OO O.OOE+OO 1.02E-Ol 

2.00E+03 6. 44E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 44E-02 

4.00E+03 2.SSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.SSE-02 

S.OOE+03 1.61E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.61E-02 

7.00E+03 6. 39E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6.39E~03 

8.00E+03 4.03E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.03E-03 

1.OOE+04 i.60E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.60E-03 

2.00E+04 1. 57E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.S7E-OS 

B-174 
ClASS W AHAD - 1 HICItOI1 STABU PHOSPHORUS 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.S7E-03 1.80E-04 

2.00E-Ol 3. 92E-03 S.26E-04 

3.00E-Ol 6. 93E-03 1.lSE-03 

4.00E-Ol 1.04E-02 2.12E-03 

S.OOE-Ol 1. 43E-02 3. 47E-03 

6.00E-Ol 1. 83E-02 5.l8E-03 

7.00E-Ol 2.2SE-02 7. 24E-03 

8.00E-Ol 2. 66E-02 9.61E-03 

9.00E-Ol 3.08E-02 1. 22E-02 

1.OOE+OO 3. 49E-02 3. 49E-02 1.5lE-02 1.5lE-02 

2.00E+OO 3.40E-02 6. 89E-02 3.l8E-02 4. 68E-02 

3.00E+OO 2. 23E-02 9.11E-02 2.4lE-02 7.09E-02 

4.00E+OO 1. 54E-02 1.06E-Ol 1.39E-02 8. 48E-02 

S!,OOE+OO 1.16E-02 1.18E-Ol 7. 48E-03 9.23E-02 

6.00E+OO 9.33E-03 1. 27E-0l 4.13E-C3 9.64E-02 

7.00E+OO 7. 85E-03 1.3SE-Ol 2. 47E-03 9. 89E-02 

8.00E+OO 6.81E-03 1.42E-Ol 1. 65E-03 1. OlE-Ol 

9.00E+OO 6.06E-03 1. 48E-Ol 1. 23E-03 1.02E-Ol 

1.OOE+Ol 5.50E-03 1.S4E-Ol 1.OlE-03 1.03E-Ol 

2.00E+Ol 3. 39E-03 1. 94E-Ol 5. 93E-04 1.lOE-Ol 

3.00E+Ol 2. 55E-03 2.23E-0l 4.72E-04 1.l5E-0l 4~OOE+Ol 1. 96E-03 2.4SE-Ol 3. 82E-04 1.19E-Ol 

5.00E+Ol 1.53E-03 2. 63E-Ol 3.13E-04 1. 23E-Ol 

6.00E+Ol 1. 22E-03 2. 76E-Ol 2.60E-04 1.2SE-Ol 

7.00E+0l 9. 86E-04 2. 87E-0l 2.l8E-04 1. 28E:-Ol 

8.00E+Ol 8.09E-04 2. 96E-Ol 1. 84E-04 1.30E-Ol 

9.00E+Ol 6. 74E-04 3.03E-Ol 1.57E-04 1.3lE-Ol 

1.OOE+02 5. 69E-04 3.09E-Ol 1. 35E-04 1. 33E-Ol 

2.00E+02 1. 73E-04 3.40E-0l 3.71E-05 1.40E-0l 

3.00E+02 S.9lE-OS 3.S3E-Ol 1. 44E-05 1.43E-Ol 

4.00E+02 6. 44E-OS 3.60E-Ol 8. 28E-06 1. 44E-0l 

S.OOE+02 5. 58E-OS 3. 66E-Ol 6. 48E-06 1. 44E-Ol 

6.00E+02 5.l7E-OS 3.71E-Ol S.82E-06 1.4SE-Ol 

7.00E+02 4.90E-05 3. 76E-Ol S.46E-06 1. 45E-Ol 

8.00E+02 4. 66E-05 3.'8lE-Ol S.19E-06 1. 46E-Ol 

9.00E+02 4.4SE-05 3. 86E-Ol 4. 95E-06 1.47E-Ol 

1.OOE+03 4. 25E-OS 3.90E-Ol 4.72E-06 l.47E-Ol 

2.00E+03 2. 68E-OS 4. 24E-Ol 2. 97E-06 1.SlE-Ol 

4.00E+03 1.06E-OS 4.S9E-Ol 1.18E-06 1.SSE-Ol 

5.00E+03 6. 69E-06 4.67E-Ol 7. 44E-07 1. 56E-Ol 

7.00E+03 2. 66E-06 4. 76E-Ol 2.95E-07 1.S7E-Ol 

8.00E+03 1. 67E-06 4. 78E-Ol 1. 86E-07 I.S7E-Ol 

9.00E+03 1.0SE-06 4.80E-Ol 1. 17E-07 I.S7E-Ol 

1.00E+04 6. 64E-07 4.80E-Ol 7. 38E-08 1. 57E-Ol 

B-175 
CLASS V AHAD ... 1 MICRO. BALFLIPE- 1.43»+01 DAYS PHOSPHOR.US 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 8. 64E-02 2.75E-Ol 2.33E-Ol 3.94E-02 6. 34E-Ol 

2.00E-Ol 1.21E-Ol 2. 63E-Ol 1. 95E-Ol 4.91E-02 6. 29E-Ol 

3.00E-Ol 1. 53E-Ol 2. 52E-Ol 1.63E-0l 5.29E-02 6.22E-Ol 

4.00E-Ol 1.80E-Ol 2. 42E-Ol 1. 37E-Ol 5. 54E-02 6.15E-Ol 

5.00E-Ol 2.01E-Ol 2.34E-Ol 1.14E-0l 5.70E-02 6.06E-Ol 

6.00E-Ol 2.18E-Ol 2.26E-Ol 9.5BE-02 5. 79E-02 5. 98E-Ol 

7.00E-Ol 2. 32E-Ol 2.19E-Ol B.02E-02 5.B2E-02 5.B9E-Ol 

B.OOE-Ol 2.42E-Ol 2.12E-Ol 6.71E-02 5.79E-02 5. BOE-Ol 

9.00E-Ol 2.51E-Ol 2.06E-Ol 5.61E-02 5.72E-02 5.71E-Ol 

1.OOE+OO 2.57E-Ol 2.0lE-Ol 4.70E-02 5.61E-02 5.61E-Ol 

2.00E+OO 2.70E-Ol 1.61E-Ol 7.91E-03 3.58E-02 4. 75E-Ol 

3.00E+OO 2. 55E-Ol 1.38E-Ol 1. 33E-03 1.B3E-02 4.12E-Ol 

4.00E+OO 2. 36E-Ol 1. 24E-Ol 2. 24E-04 8.73E-03 3.69E-Ol 

5.00E+OO 2.19E-Ol 1.13E-Ol 3.7BE-05 4.16E-03 3. 36E-Ol 

6.00E+OO 2.03E-Ol 1.05E-0l 6. 36E-06 2.07E-03 3.10E-0l 

7.00E+OO 1.B9E-Ol 9. 83E-02 1.07E-06 1.12E-03 2. 88E-Ol 

8.00E+OO 1.76E-Ol 9. 22E-02 1. BOE-07 6.BIE-04 2.69E-Ol 

9.00E+OO 1.65E-Ol 8. 65E-02 3.04E-OB 4.71E-04 2. 52E-Ol 

1.OOE+Ol 1.54E-Ol 8.13E-02 O.OOE+OO 3.65E-04 2.36E-Ol 

2.00E+Ol 8. 28E-02 4.40E-02 O.OOE+OO 1. 55E-04 1.27E-Ol 

4.00E+Ol 2. 65E-02 1.29E-02 O.OOE+OO 4. 45E-05 3. 95E-02 

5.00E+Ol 1. 54E-02 7.01E-03 O.OOE+OO 2. 39E-05 2. 25E-02 

7.00E+0l 5. 46E-03 2.06E-03 O.OOE+OO 6. 85E-06 7. 52E-03 

8.00E+Ol 3. 29E-03 1.1lE-03 O.OOE+OO 3. 67E-06 4.41E-03 

9.00E+Ol 1. 99E-03 6.04E-04 O.OOE+OO 1. 97E-06 2.60E-03 

1.OOE+02 1.21E-03 3. 27E-04 O.OOE+OO 1.06E-06 1. 54E-03 

2.00E+02 9.00E-06 7.06E-07 O.OOE+OO O.OOE+OO 9.71E-06 

3.00E+02 6. 75E-08 O.OOE+OO O.OOE+OO O.OOE+OO 6. 75E-08 

B-176 
CLASS W JHAD ... 1 lUCltOB BALPLll'E= 1.43£+01 DAYS PBOSPIlOJtUS 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24...:HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-0l 1. 56E-03 1.79E-04 

2.00E-Ol 3.S9E-03 S.21E-04 

3.00E-Ol 6. 83E-03 1. 13E-03 

4.00E-Ol 1.02E-02 2.0SE-03 

S.OOE-Ol 1. 39E-02 3.3SE-03 

6. OOE-o 1 1.7SE-02 S.03~-03 

7.00E-Ol 2. 17E-02 7.00E-03 

8.00E-ol 2. 56E-02 9.2SE-03 

9.00E-Ol 2.9SE-02 1.17E-02 

1.00E+OO 3. 32E-02 3. 32E-02 1. 44E-02 1. 44E-02 

2.00E+OO 3.09E-02 6.2SE-02 2.SSE-02 4.2SE-02 

3.00E+OO 1. 92E-02 7.8SE-02 2.0SE-02 6.13E-02 

4.00E+OO 1.27E-02 8.77E-02 1. 14E-02 6.9SE-02 

5.00E+OO 9.10E-03 9. 26E-02 S.S7E-03 7. 24E-02 

6.00E+OO 6. 98E-03 9. 52E-02 3.09E-03 7.21E-02 

7.00E+OO S.S9E-03 9.63E-02 1. 76E-03 7.04E-02 

S.OOE+OO 4. 62E-03 9. 64E-02 1. 12E-03 6. 82E-02 

9.00E+OO 3. 91E-03 9.S7E-02 7. 96E-04 6.SSE-02 

1.00E+Ol 3.3SE-03 9. 46E-02 6.20E-04 6. 33E-02 

2.00E+Ol 1. 28E-03 7. 36E-02 2.2SE-04 4. 16E-02 

3.00E+Ol S.9SE-04 S.21E-02 l.lOE-04 2.6SE-02 

4.00E+Ol 2. 82E-04 3.S3E-02 S.49E-OS 1.71E-02 

S.OOE+Ol 1. 36E-04 2. 32E-02 2.77E-OS 1.0SE-02 

6.00E+Ol 6.64E-OS· I.S0E-02 1. 42E-OS 6.S3E-03 

7.00E+Ol 3.31E-OS 9. 62E-03 7.30E-06 4. 28E-03 

S.OOE+Ol 1. 67E-OS 6.lOE-03 3.S0E-06 2. 68E-03 

9.00E+Ol S.S6E-06 3.SSE-03 1.99E-06 1. 67E-03 

1.00E+02 4.4SE-06 2. 42E-03 1.0SE-06 1.04E-03 

2.00E+02 1.06E-OS 2.0SE-OS O.OOE+OO S.SSE-06 

8-177 
CLASS II AHAD = 1 KICRO. STABLK SULPRUB. 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7. 54E-02 2. 76E-Ol 2. 35E-Ol 3.96E-02 6. 26E-Ol 

2.00E-OI 9. 58E-02 2.6SE-Ol 1. 97E-OI 4. 96E-02 6.08E-OI 

3.00E-Ol 1. 12E-0l 2. 56E-Ol I.66E-Ol S.37E-02 S.87E-OI 

4.00E-OI I.2IE-OI 2.47E-Ol 1. 39E-OI S.64E-02 S.64E-Ol 

5.00E-OI 1. 25E-Ol 2.40E-OI 1. 17E-OI 5. 84E-02 S.40E-Ol 

6.00E-Ol 1. 26E-Ol 2. 33E-Ol 9. 86E-02 5. 96E-02 S.17E-Ol 

7.00E-Ol 1.2SE-Ol 2.27E-Ol 8.29E-02 6.02E-02 4. 94E-OI 

8.00E-Ol I.22E-Ol 2.2IE-OI 6. 97E-02 6.02E-02 4. 73E-Ol 

9.00E-Ol 1. 19E-0l 2. 16E-Ol 5. 86E-02 5. 98E-02 4.S3E-Ol 

1.00E+OO 1. 16E-Ol 2.11E-Ol 4. 93E-02 5. 89E-02 4. 35E-Ol 

2.00E+OO 8.90E-02 1.17E-Ol 8.12E-03 3.9SE-02 3.l4E-0l 

3.00E+OO 8.02E-02 1.60E-Ol 1.S4E-03 2. 12E-02 2. 63E-Ol 

4.00E+OO 7. 69E-02 1. SOE-Ol 2.72E-04 1.06E-02 2. 38E-Ol 

S.OOE+OO 7.49E-02 1.4SE-Ol 4. 82E-05 5.30E-03 2.2SE-Ol 

6.00E+OO 7. 33E-02 I.41E-Ol 8. 51E-06 2.77E-03 2. 17E-Ol 

7.00E+OO 7. 17E-02 1. 38E-OI 1. 51E-06 1.S7E-03 2.11E-OI 

8.00E+OO 7.03E-02 1. 36E-OI 2.66E-07 1.00E-03 2.07E-Ol 

9.00E+OO 6. 88E-02 1. 34E-Ol 4.70E-08 7. 29E-04 2.03E-Ol 

1.00E+OI 6.7SE-02 1. 32E-Ol O.OOE+OO 5. 93E-04 2.00E-Ol 

2.00E+OI 5. 63E-02 1. 16E-Ol O.OOE+OO 4.09E-04 1. 73E-Ol 

3.00E+OI 4. 82E-02 I.02E-Ol O.OOE+OO 3.S6E-04 I.SIE-Ol 

4.00E+Ol 4. 24E-02 9.0lE-02 O.OOE+OO 3.10E-04 1. 33E-Ol 

S.OOf.;+Ol 3. 82E-02 7. 93E-02 O.OOE+OO 2.70E-04 I.18E-Ol 

6.00E+Ol 3.S1E-02 6. 98E-02 O.OOE+OO 2.3SE-04 1.05E-Ol 

7.00E+Ol 3. 29E-02 6.l4E-02 O.OOE+OO 2.04E-04 9.4SE-02 

8.00E+Ol 3. 12E-02 5.40E-02 O.OOE+OO 1. 78E-04 8.S4E-02 

9.00E+Ol 3.00E-02 4.7SE-02 O.OOE+OO 1.5SE-04 7. 17E-02 

1.OOE+02 2. 91E-02 4.l8E-02 O.OOE+OO 1. 35E-04 7.l0E-02 

2.00E+02 2. 56E-02 1.lSE-02 O.OOE+OO 3. 37E-OS 3. 72E-02 

3.00E+02 2. 44E-02 3.lSE-03 O.OOE+OO 8. 43E-06 2. 76E-02 

4.00E+02 2-:3SE-02 8. 55E-04 O.OOE+OO 2.11E-06 2. 44E-02 

5.00E+02 2.27E-02 2. 31E-04 O.OOE+OO 5.27E-07 2. 29E-02 

6.00E+02 2. 19E-02 6.l9E-OS O.OOE+OO 1.32E-07 2.20E-02 

7.00E+02 2.l2E-02 1. 65E-OS O.OOE+OO 3. 29E-Q8 2.l2E-02 

8.00E+02 2.04E-02 4.40E-06 O.OOE+OO O.OOE+OO 2.04E-02 

9.00E+02 1. 97E-02 1. 16E-06 O.OOE+OO O.OOE+OO I.97E-02 

1.00E+03 1.91E-02 3.08E-07 O.OOE+OO O.OOE+OO 1. 91E-02 

2.00E+03 1.3SE-02 O.OOE+OO O·90E+OO O.OOE+OO 1.3SE-02 

4.00E+03 6. 74E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 74E-03 

5.00E+03 4.17E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4.17E-03 

7.00E+03 2. 38E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 38E-03 

8.00E+03 1. 69E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 69E-03 

9.00E+03 1. 19E-:03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 19E-03 

1.00E+04 8. 43E-04 O.OOE+OO O.OOE+OO O.OOE+OO 8. 43E-04 

2.00E+04 2. 64E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2. 64E-05 

B-178 
CLASS V AIIAD =< 1 MICRO. STABLE SULPIIUIt 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

hOOE-Ol 1.ISE-02 I. 32E-03 

2.00E-OI 2. 79E-02 3.19E-03 

3.00E-OI 4.67E-02 S.S7E-03 

4. OOE-O 1 6.70E-02 S.40E-03 

5.00E-OI S.74E-02 1.16E-02 

6. OOE-O 1 I.07E-OI 1.5IE-02 

7.00E-Ol I. 26E-OI 1.SSE-02 

S.OOE-Ol 1.44E-Ol 2. 26E-02 I 9.00E-Ol 1.60E-01 2. 65E-02 

1.00E+OO 1. 74E-OI 1. 74E-Ol 3.06E-02 3.06E-OZ 

2.00E+00 S.2SE-02 2.57E-Ol 3.72E-02 6.77E-02 

3.00E+00 2.71E-02 2.S4E-Ol 2. 46E-02 9. 23E-02 

4.00E+OO 1.13E-02 2.9SE-0l 1. 34E-02 I.06E-Ol 

5.00E+OO 6. 34E-03 3.02E-OI 6.S9E-03 1.13E-Ol 

6.00E+OO 4. 39E-03 3.06E-Ol 3.5SE-03 1.16E-Ol 

7.00E+OO 3. 49E-03 3.lOE-Ol 1. 99E-03 1.lSE-Ol 

S.OOE+OO 3.02E-03 3.l3E-OI 1.23E-03 1.19E-01 

9.00E+OO 2.77E-03 3.lSE-Ol S.66E-04 1.20E-Ol 

I.OOE+OI 2.6lE-03 3.lSE-OI 6.S7E-04 1.2IE-OI 

2.00E+OI 2.02E-03 3.40E-OI 4.4lE-04 1. 26E-OI 

3.00E+OI 1. 64E-03 3.5SE-Ol 3.71E-04 1.30E-Ol 

4.00E+OI 1. 35E-03 3.73E-Ol 3.l4E-04 1. 33E-Ol 

S.OOE+OI 1.12E-03 3.S5E-Ol 2. 67E-04 1.36E-01 

6.00E+Ol 9. 37E-:,04 3. 95E-Ol 2. 28E-04 1. 39E-Ol 

7.00E+OI 7. 92E-04 4.04E-OI 1.96E-04 1.4lE-0l 

S.OOE+OI 6. 74E-04 4.11E-Ol 1. 69E-04 1. 43E-Ol 

9.00E+Ol S.7SE-04 4.17E-Ol 1. 46E-04 I. 44E-Ol 

1.OOE+02 4.9SE-04 4. 23E-OI 1. 27E-04 1. 46E-Ol 

2.00E+02 1. 33E-04 4.50E-Ol 3. 27E-OS I.S2E-Ol 

3.00E+02 4. 22E-05 4.S7E-Ol 9. ISE-06 1. 54E-Ol 

4.00E+02 1. 69E-OS 4.60E-Ol 2. 99E,...06 1.5SE-Ol 

S.OOE+02 9.6SE-06 4.6IE-OI 1.3SE-06 1.SSE-Ol 

6.00E+02 7. 54E-06 4. 62E-Ol 9.07E-07 I.S5E-Ol 

7.00E+02 6. 79E-06 4. 63E-Ol 7. 72E-07 1.5SE-01 

S.OOE+02 6.42E-06 4.64E-Ol 7.1SE-07 1.55E-01 

9.00E+02 6.l7E-06 4. 64E-Ol 6.S7E-07 1.5SE-Ol 

. \. 

1.OOE+03 5.95E-06 4.6SE-Ol 6.6lE-07 1.5SE-Ol 

2.00E+03 4.21E-06 4.70E-OI 4. 67E-07 1. 56E-Ol 

4.00E+03 2.lOE-06 4.76E-Ol 2. 34E-07 1. 57E-Ol 

5.00E+03 1. 49E-06 4.7SE-Ol 1.6SE-07 1. 57E-Ol 

7.00E+03 7.44E-07 4.S0E-Ol S.26E-OS 1.57E-Ol 

S.OOE+03 5. 26E-07 4.S0E-Ol 5.S4E-OS 1. 57E-Ol 

9.00E+03 3.72E-07 4.SlE-Ol 4.13E-OS 1.S7E-Ol 

1.OOE+04 2. 63E-07 4.SlE-Ol 2. 92E-OS 1. 57E-Ol 

B-179 
CLASS V AHAD = 1 IIICK.ON lIALPLIFB- 8.748+01 DAYS SOLI'IJIt 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7. 53E-02 2. 76E-01 2. 34E-01 3.95E-02 6. 25E-01 

2.00E-01 9. 57E-02 2. 65E-01 1. 97E-01 4. 96E-02 6.07E-01 

3.00E-01 1.llE-Ol 2.55E-01 1.65E-0l 5. 36E-02 5. 85E-01 

4.00E-01 1.20E-01 2. 46E-01 1. 39E-Ol 5. 63E-02 5. 62E-01 

5.00E-01 1. 24E-01 2.39E-01 1. 17E-01 5. 81E-02 5. 38E-01 

6.00E-01 1. 25E-01 2. 32E-01 9. 82E-02 5. 93E-02 5. 14E-Ol 

7.00E-01 1. 24E-01 2. 25E-0l 8.25E-02 5.99E-02 4. 92E-01 

8.00E-01 1.21E-Ol 2. 19E-01 6. 93E-02 5. 98E-02 4.70E-01 

9.00E-01 1. 18E-01 2.14E-01 S.82E-02 S.93E-02 4.50E-Ol 

1.00E+OO 1.lSE-Ol 2.09E-Ol 4. 89E-02 S.84E-02 4.31E-01 

2.00E+OO 8. 76E-02 1. 74E-01 8. S8E-03 3.88E-02 3.10E-Ol 

3.00E+OO 7.83E-02 1.S6E-01 1. SOE-03 2.07E-02 2.S7E-01 

4.00E+OO 7.4SE-02 1.46E-01 2. 64E-04 1.03E-02 2.31E-01 

S.OOE+OO 7.20E-02 1. 39E-01 4. 63E-OS S.lOE-03 2. 16E-01 

6.00E+OO 6. 99E-02 1. 34E";Ol 8.·12E-06 2. 64E-03 2.07E-01 

7.00E+OO 6. 78E-02 1.31E-01 1. 42E-06 1. 49E-03 2.00E-01 

8.00E+OO 6.S9E-02 1.28E-01 2. SOE-07 9.42E-04 1.94E-01 

9.00E+OO 6.41E-02 1.2SE-01 4. 38E-08 6. 78E-04 1. 89E-Ol 

1.OOE+01 6. 24E-02 1.22E-01 O.OOE+OO S.48E-04 1.8SE-01 

2.00E+01 4.80E-02 9. 92E-02 O.OOE+OO 3. 49E-04 1. 48E-01 

3.00E+01 3.80E-02 8.07E-02 O.OOE+OO 2.81E-04 1. 19E-01 

4.00E+01 3.09E-02 6.S6E-02 O.OOE+OO 2. 26E-04 9.6 

S.OOE+Ol 2.S7E-02 S.33E-02 O.OOE+OO 1.81E-04 7.9 

6.00E+01 2. 18E-02 4. 34E-02 O.OOE+OO 1. 46E-04 6.S3E-02 

7.00E+01 1.89E-02 3.S2E-02 O.OOE+OO 1. 17E-04 S.42E-02 

8.00E+Ol 1. 66E-02 2. 86E-02 O.OOE+OO 9.44E-05 4.S3E-02 

9.00E+01 1.47E-02 2. 33E-02 O.OOE+OO 7.S9E-OS 3.81E-02 

1.00E+02 1. 32E-02 1. 89E-02 O.OOE+OO 6.lOE-OS 3.21E-02 

2.00E+02 S.2SE-03 2. 36E-03 O.OOE+OO 6.91E-06 7. 62E-03 

3.00E+02 2. 26E-03 2. 92E-04 O.OOE+OO 7.82E-07 2.S6E-03 

4.00E+02 9. 86E-04 3.S9E-OS O.OOE+OO 8.84E-08 1.02E-03 

S.OOE+02 4.31E-04 4. 38E-06 O.OOE+OO 1.00E-08 4.3SE-04 

6.00E+02 1. 88E-04 S.32E-07 O.OOE+OO O.OOE+OO 1. 89E-04 

7.00E+02 8. 23E-OS 6. 43E-08 O.OOE+OO O.OOE+OO 8. 24E-OS 

8.00E+02 3.60E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.60E-OS 

9.00E+02 1.S7E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1. S7E-OS 

. ', ... 1.OOE+03 6. 88E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6. 88E-06 

B-180 
ClASS If AHAD - 1 MICRON BA.LFLIFK= 8.74£+01 DAYS SULPBIJR 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1.ISE-02 1. 32E-03 

2.00E-Ol 2. 79E-02 3.1SE-03 

3.00E-Ol 4. 66E-02 5. 56E-03 

4.00E-Ol 6.6SE-02 S.3SE-03 

5.00E-Ol S.71E-02 1. 15E-02 

6.00E-Ol 1.07E-Ol 1.50E-02 

7.00E-Ol 1.25E-Ol I.S7E-02 

S.OOE-Ol 1. 43E-Ol 2. 25E-02 

9.00E-Ol 1.5SE-0l 2. 64E-02 

1.00E+00 1. 13E-Ol 1. 13E-Ol 3.03E-02 3.03E-02 

2.00E+00 S.15E-02 2. 53E-Ol 3.66E-02 6. 67E-02 

3.00E+00 2. 64E-02 2. 77E-Ol 2.40E-02 9.02E-02 

4.00E+OO 1.10E-02 2.S6E-Ol 1.30E-02 1.02E-Ol 

5.00E+00 6.09E-03 2.90E-Ol 6. 63E-03 1.0SE-Ol 

6.00E+00 4.1SE-03 2. 92E-Ol 3. 42E-03 1.11E-0l 

7.00E+00 3.30E-03 2. 93E-Ol I.SSE-03 1.12£-01 

S.OOE+OO 2.S4E-03 2. 93E-Ol 1. 16E-03 1. 12E-0l 

9.00E+OO 2.5SE-03 2. 94E-Ol S.07E-04 1. 12E-Ol 

1.00E+Ol 2.41E-03 2. 94E-Ol 6. 35E-04 1.12E-Ol 

2.00E+Ol 1.72E-03 2.90E-ol 3.76E-04. 1.07E-Ol 

3.00E+Ol 1.29E-03 2.S2E-Ol 2. 92E-04 1.02E-Ol 

4.00E+Ol 9.S0E-04 2. 72E-Ol 2.2SE-04 9.71E-02 

5.00E+Ol 7.52E-04 2. 59E-Ol I.S0E-04 9. 16E-02 

6.00E+Ol 5.S2E-04 2. 46E-Ol 1. 42E-04 S.62E-02 

7.00E+Ol 4. 55E-04 2.32E-Ol 1.l3E-04 S.OSE-02 

S.OOE+Ol 3.5SE-04 2.1SE-Ol S.97E-05 7. 56E-02 

9.00E+Ol 2.S3E-04 2.04E-Ol 7.17E-05 7.06E-02 

1.00E+02 2.2SE-04 1.91E-Ol S.74E-OS 6. 59E-02 

2.00E+02 2.13E-05 9.21E-02 6. 69E-06 3. 12E-02 

3.00E+02 3. 91E-06 4. 24E-02 S.49E-07 1. 43E-02 

4.00E+02 7.07E-07 1.93E-02 1.25E-07 6. 49E-03 

5.00E+02 1.S4E-07 S.76E-03 2. 57E-OS 2. 94E-03 

6.00E+02 6.4SE-OS 3. 97E-03 O.OOE+OO 1. 33E-03 

7.00E+02 2. 64E-08 I.S0E-03 O.OOE+OO 6.04E-04 

8.00E+02 1.l3E-08 S.16E-04 O.OOE+OO 2. 73E-04 1 

I 

I .. :' . ;'" 

I .. ',' 

8-181 
CLASS W AMAD - 1 HICR.ON STABLE CHLORINE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI I.07E-Ol 2. 76E-OI 2.35E-OI 2.IOE-02 6.39E-OI 

2.00E-Ol 1. 55E-Ol 2. 65E-Ol I. 97E-Ol 1. 96E-02 6.3BE-Ol 

3.00E-Ol 1.9BE-Ol 2.56E-Ol 1. 66E-Ol 1.68E-02 6.36E-Ol 

4.00E-Ol 2. 34E-Ol 2. 47E-Ol 1. 39E-Ol 1.43E-02 6. 35E-Ol 

S.OOE-Ol 2. 64E-Ol 2.40E-0l 1.17E-Ol 1.22E-02 6. 33E-Ol 

6.00E-Ol 2.B9E-Ol 2. 33E-Ol 9. 86E-02 1.05E-02 6.3lE-OI 

7.00E-Ol 3.BE-OI 2. 27E-Ol 8. 29E-02 9.0lE-03 6. 29E-Ol 

B.OOE-Ol 3. 29E-Ol 2.2lE-OI 6. 97E-02 7.77E-03 6. 27E-OI 

9.00E-OI 3. 44E-Ol 2.16E-OI 5.B6E-02 6.72E-03 6.2SE-OI 

I.OOE+OO 3.S6E-OI 2.IIE-OI 4. 93E-02 S.B3E-03 6. 22E-OI 

2.00E+OO 4.0BE-OI 1. 77E-Ol 8.72E-03 1. 66E-03 S.95E-Ol 

3.00E+OO 4.05E-OI 1.60E-Ol 1.S4E-03 6. 39E-04 5. 67E-OI 

4.00E+OO 3. 89E-Ol 1. SOE-OI 2.72E-04 3.08E-04 S.39E-OI 

5.00E+OO 3.6BE-OI 1.45E-OI 4.B2E-OS 1. 74E-04 S.13E-OI 

6.00E+OO 3.47E-0l 1.4IE-Ol B.5IE-06 1.12E-04 4.B8E-0l 

7.00E+OO 3. 27E-OI I. 38E-OI 1.SlE-06 8.16E-05 4.6SE-OI 

8.00E+OO 3.07E-OI 1.36E-OI 2. 66E-07 6. 63E-05 4.43E-OI 

9.00E+OO 2. 88E-Ol I. 34E-OI 4.70E-OB 5.B3E-OS 4. 22E-OI 

I.OOE+OI 2.7IE-0l I. 32E-OI O.OOE+OO S.40E-OS 4.03E-Ol 

2.00E+OI 1.47E-Ol 1.16E-OI O.OOE+OO 4. 38E-05 2. 63E-OI 

3.00E+Ol 8. 34E-02 1.02E-OI O.OOE+OO 3. 82E-OS I. B6E-O 

4.00E+OI S.OSE-02 9.0IE-02 O.OOE+OO 3. 32E-OS I. 

5.00E+OI 3.30E-02 7. 93E-02 O.OOE+OO 2. 89E-05 1.1 

6.00E+OI 2. 33E-02 6. 98E-02 O.OOE+OO 2.S2E-05 9.3IE-02 

7.00E+OI 1.77E-02 6.14E-02 O.OOE+OO 2.19E-OS 7.9lE-02 

B.OOE+Ol 1.4IE-02 S.40E-02 O.OOE+OO 1.9IE-05 6.8lE-02 

9.00E+OI 1.17E-02 4.7SE-02 O.OOE+OO I. 66E-OS S.92E-02 

I.OOE+02 9. 95E-03 4.18E-02 O.OOE+OO 1.4SE-OS S.IBE-02 

2.00E+02 2. 64E-03 1.ISE-02 O.OOE+OO 3.6IE-06 1. 42E-02 

3.00E+02 7.27E-04 3.ISE-03 O.OOE+OO 9.04E-07 3. 88E-03 

4.00E+02 1.99E-04 8.SSE-04 O.OOE+OO 2. 26E-07 I.OSE-03 

S.OOE+02 S.39E-OS 2.3IE-04 O.OOE+OO 5.6SE-OB 2. BSE-04 

6.00E+02 1.4SE-OS 6.l9E-OS O.OOE+OO 1.4lE-08 7. 64E-OS 

7.00E+02 3.90E-06 1.6SE-05 O.OOE+OO O.OOE+OO 2.04E-OS 

B.OOE+02 1.04E-06 4.40E-06 O.OOE+OO O.OOE+OO 5. 44E-06 

9.00E+02 2. 76E-07 1.16E-06 O.OOE+OO O.OOE+OO 1. 44E-06 

1.OOE+03 7. 32E-08 3.08E-07 O.OOE+OO O.OOE+OO 3. BlE-07 

B-182 
CLASS W AHAD "" 1 MICRON STABLE CHLORINE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 5. 19E-04 O.OOE-OO 

2.00E-Ol 1.43E-03 O.OOE-OO 

3.00E-Ol 2. 66E-03 O.OOE-OO 

4.00E-Ol 4. 16E-03 O.OOE-OO 

5.00E-Ol 5. 89E-03 O.OOE-OO 

6.00E-Ol 7.81E-03 O.OOE-OO 

7.00E-Ol 9. 89E-03 O.OOE-OO 

8.00E-Ol 1.21E-02 O.OOE-OO 

9.00E-Ol 1. 44E-02 O.OOE-OO 

1.00E+OO 1. 69E-02 1. 69E-02 O.OOE-OO O.OOE-OO 

2.00E+OO 2.70E-02 4. 39E-02 O.OOE-OO O.OOE-OO 

3.00E+OO 2. 83E-02 7. 22E-02 O.OOE-OO O.OOE-OO 

4.00E+OO 2. 75E-02 9.97E-02 O.OOE-OO O.OOE-OO 

5.00E+OO 2. 62E-02 1. 26E-Ol O.OOE-OO O.OOE-OO 

6.00E+OO 2.48E-02 1.51E-Ol O.OOE-OO O.OOE-OO 

7.00E+OO 2. 34E-02 1. 74E-Ol O.OOE+OO O.OOE-OO 

8.00E+OO 2.20E-02 1.96E-Ol O.OOE+OO O.OOE-OO 

9.00E+OO 2.06E-02 2. 17E-Ol O.OOE+OO O.OOE-OO 

1.00E+Ol 1.94E-02 2. 36E-Ol O.OOE+OO O.OOE-OO 

2.00E+Ol 1.05E-02 3.76E-Ol O.OOE+OO O.OOE-OO 

3.00E+Ol 5. 94E-03 4. 53E-0l O.OOE+OO O.OOE-OO 

4.00E+Ol 3. 58E-03 4. 99E-Ol O.OOE+OO O.OOE-OO 

5.00E+Ol 2.33E-03 5.27E-Ol O.OOE+OO O.OOE-OO 

6.00E+Ol 1.64E-03 5. 46E-O 1 O.OOE+OO O.OOE-OO 

7.00E+Ol 1.24E-03 5.60E-Ol O.OOE+OO O.OOE-OO 

8.00E+Ol 9.88E-04 5. 71E-Ol O.OOE+OO O.OOE-OO 

9.00E+Ol 8. 19E-04 5.80E-Ol O.OOE+OO O.OOE-OO 

1.00E+02 6. 95E-04 5.87E-Ol O.OOE+OO O.OOE-OO 

2.00E+02 1. 84E-04 6. 25E-Ol O.OOE+OO O.OOE-OO 

3.00E+02 5.07E-05 6. 35E-Ol O.OOE+OO O.OOE-OO 

4.00E+02 1. 39E-05 6.38E-0l O.OOE+OO O.OOE-OO 

5.00E+02 3. 76E-06 6. 39E-Ol O.OOE+OO O.OOE-OO 

6.00E+02 1.0IE-06 6.39E-Ol O.OOE+OO O.OOE-OO 

7.00E+02 2.72E-07 6.39E-Ol O.OOE+OO O.OOE-OO •. 1. 8.00E+02 7.25E-08 6. 39E-Ol O.OOE+OO O.OOE-OO 

9.00E+02 1. 93E-08 6.39E-Ol O.OOE+OO O.OOE-OO 

B-183 
CLASS V AHAD == 1 HICltON BAI..FLIFE- 1.10£+08 DAYS CHLORINE 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 1.07E-01 2. 76E-Ol 2. 35E-Ol 2.l0E-02 6.39E-Ol 

2.00E-OI 1. 55E-Ol 2. 65E-Ol 1.97E-01 1. 96E-02 6. 38E-Ol 

3.00E-Ol 1. 98E-Ol 2. 56E-Ol 1.66E-01 1. 68E-02 6.36E-Ol 

4.00E-ol 2. 34E-Ol 2. 47E-Ol 1. 39E-Ol 1. 43E-02 6. 35E-Ol 

5.00E-Ol 2. 64E-Ol 2.40E-Ol 1.17E-0l 1.22E-02 6. 33E-Ol 

6.00E-Ol 2. 89E-Ol 2. 33E-Ol 9. 86E-02 1.05E-02 6.3lE-01 

7.00E-Ol 3.llE-Ol 2. 27E-Ol 8. 29E-02 9.0lE-03 6.29E-Ol 

8.00E-Ol 3. 29E-OI 2.21E-Ol 6.97E-02 7. 77E-03 6.27E-Ol 

9.00E-Ol 3. 44E-OI 2.l6E-0l 5. 86E-02 6.72E-03 6. 25E-OI 

1.00E+00 3. 56E-Ol 2.UE-Ol 4. 93E-02 5. 83E-03 6. 22E-Ol 

2.00E+00 4.08E-Ol 1. 77E-Ol 8.72E-03 1.66E-03 5. 95E-Ol 

3.00E+00 4.05E-Ol 1.60E-Ol l.54E-03 6. 39E-04 5. 67E-Ol 

4.00E+00 3. 89E-Ol 1.50E-01 2.72E-04 3.08E-04 5. 39E-Ol 

5.00E+00 3. 68E-Ol 1.45E-01 4. 82E-05 1. 74E-04 5.13E-Ol 

6.00E+00 3. 47E-Ol l.41E-0l 8.5lE-06 l.12E-04 4. 88E-0l 

7.00E+00 3. 27E-Ol 1. 38E-Ol 1. 51E-06 8.l6E-05 4. 65E-Ol 

8.00E+00 3.07E-Ol 1.36E-Ol 2.66E-07 6. 63E-05 4.43E-Ol 

9.00E+00 2. 88E-Ol 1. 34E-Ol 4.70E-08 5. 83E-05 4. 22E-Ol 

1.00E+Ol 2. 71E-Ol 1. 32E-Ol O.OOE+OO 5.40E-05 4.03E-Ol 

2.00E+Ol 1.47E-Ol 1. 16E-Ol O.OOE+OO 4. 38E-05 2. 63E-Ol 

3.00E+Ol 8. 34E-02 1.02E-01 O.OOE+OO 3. 82E-05 1.86E-0 

4.00E+Ol 5.05E-02 9.01E-02 O.OOE+OO 3. 32E-05 1.4 

5.00E+OI 3.30E-02 7. 93E-02 O.OOE+OO 2. 89E-05 1.12E-0 

6.00E+Ol 2. 33E-02 6. 98E-02 O.OOE+OO 2. 52E-05 9.·3lE-02 

7.00E+Ol 1.77E-02 6. 14E-02 O.OOE+OO 2.l9E-05 7.9lE-02 

8.00E+Ol 1.4lE-02 5.40E-02 O.OOE+OO 1.9IE-05 6.8lE-02 

9.00E+Ol l.l7E-02 4. 75E-02 O.OOE+OO 1.66E-05 5. 92E-02 

1.00E+02 . 9. 95E-03 4. 18E-02 O.OOE+OO 1. 45E-05 5.18E-02 

2.00E+02 2.64E-03 1. 15E-02 O.OOE+OO 3.6lE-06 1.42E-02 

3.00E+02 7.27E-04 3.l5E-03 O.OOE+OO 9.04E-07 3. 88E-03 

4.00E+02 1.99E-04 8.55E-04 O.OOE+OO 2.26E-07 1.05E-03 

5.00E+02 5. 39E-05 2.3lE-04 O.OOE+OO 5. 65E-08 2. 85E-04 

6.00E+02 1.45E-05 6.l9E-05 O.OOE+OO 1.4lE-08 7.64E-05 

7.00E+02 3.90E-06 1. 65E-05 O.OOE+OO O.OOE+OO 2.04E-05 

8.00E+02 1.04E-06 4.40E-06 O.OOE+OO O.OOE+OO 5. 44E-06 

9.00E+02 2. 76E-07 1.16E-06 O.OOE+OO O.OOE+OO 1. 44E-06 

; .. -' 

. , 1.00E+03 7. 32E-08 3.08E-07 O.OOE+OO O.OOE+OO 3.8lE-07 

B-184 
ClASS V AHAD .. 1 MICRON BALFLIP'E- 1.10£+08 DAYS CHLORINE 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 5.19E-04 O.OOE-OO 

2.00E-Ol 1.43E-03 O.OOE-OO 

3.00E-Ol 2. 66E-03 O.OOE-OO 

4.00E-Ol 4.l6E-03 O.OOE-OO 

5.00E-Ol 5. 89E-03 O.OOE-OO 

6.00E-Ol 7.8lE-03 O.OOE-OO 

7.00E-Ol 9.89E-03 O.OOE-OO 

8.00E-Ol 1.2lE-02 O.OOE-OO 

9.00E-Ol 1. 44E-02 O.OOE-OO 

1.OOE+OO 1. 69E-02 1. 69E-02 O.OOE-OO O.OOE-OO 

2.00E+OO 2.70E-02 4.39E-02 O.OOE-OO O.OOE-OO 

3.00E+OO 2. 83E-02 7.22E-02 O.OOE-OO O.OOE-OO 

4.00E+OO 2.75E-02 9. 97E-02 O.OOE-OO O.OOE-OO 

5.00E+OO 2. 62E-02 1. 26E-Ol O.OOE-OO O.OOE-OO 

6.00E+OO 2. 48E-02 1.5lE-0l O.OOE-OO O.OOE-OO 

7.00E+OO 2. 34E-02 1. 74E-Ol O.OOE+OO O.OOE-OO 

8.00E+OO 2.20E-02 1.96E-Ol O.OOE+OO O.OOE-OO 

9.00E+OO 2 .• 06E-02 2.l7E-Ol O.OOE+OO O.OOE-OO 

1.OOE+Ol 1. 94E-02 2.36E-0l O.OOE+OO O.OOE-OO 

2.00E+Ol 1.05E-02 3. 76E-Ol O.OOE+OO O.OOE-OO 

3.00E+Ol 5. 94E-03 4. 53E-Ol O.OOE+OO O.OOE-OO 

4. o OE+O 1 3. 58E-03 4. 99E-Ol O.OOE+OO O.OOE-OO 

5.00E+Ol 2. 33E-03 5. 27E-Ol O.OOE+OO O.OOE-OO 

6.00E+Ol 1. 64E-03 5. 46E-Ol O.OOE+OO O.OOE-OO 

7.00E+Ol 1. 24E-03 5.60E-Ol O.OOE+OO O.QOE~OO 

8.00E+Ol 9. 88E-04 5. 71E-Ol O.OOE+OO O.OOE-OO 

9.00E+Ol 8.l9E-04 5.80E-Ol O.OOE+OO O.OOE-OO 

1.OOE+02 6. 95E-04 5.87E-Ol O.OOE+OO O.OOE-OO 

2.00E+02 1.8"4E-04 6. 25E-Ol O.OOE+OO O.OOE-OO 

3.00E+02 5.07E-05 6.35E-Ol O.OOE+OO O.OOE-OO 

4.00E+02 1.39E-05 6. 38E-Ol O.OOE+OO O.OOE-OO 

5.00E+02 3. 76E-06 6. 39E-Ol O.OOE+OO O.OOE-OO 

6.00E+02 1.OlE-06 6. 39E-Ol O.OOE+OO O.OOE-OO 

7.00E+02 2. 72E-07 6.39E-Ol O.OOE+OO O.OOE-OO .. 8.00E+02 7.25E-08 6. 39E-Ol O.OOE+OO O.OOE-OO 

9.00E+02 1. 93E-08 6. 39E-Ol O.OOE+OO O.OOE-OO 

B-185 
CLASS W AMAD = 1 MICR.ON STABLE CALCIUM 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l4E-02 2. 76E-Ol 2.3SE-Ol S.42E-02 6. 37E-Ol 

2.00E-Ol 8.02E-02 2.6SE-Ol 1.97E-Ol 9. 29E-02 6. 36E-Ol 

3.00E-Ol 9.1SE-02 2.S6E-Ol 1. 66E-Ol 1.21E-Ol 6. 34E-Ol 

4.00E-Ol 1.03E-Ol 2.47E-Ol 1.39E-Ol 1.43E-Ol 6. 32E-Ol 

S.OOE-Ol 1. 13E-Ol 2.40E-Ol 1.17E-Ol 1.59E-Ol 6. 29E-Ol 

6.00E-Ol 1. 22E-Ol 2. 33E-Ol 9. 86E-02 1.71E-Ol 6.24E-Ol 

7.00E-Ol 1. 29E"':OI 2.27E-Ol 8. 29E-02 1.80E-Ol 6.l9E-Ol 

8.00E-Ol 1.36E-Ol 2.21E-Ol 6. 97E-02 1. 86E-Ol 6.l2E-Ol 

geOOE-Ol 1.41E-0l 2.16E-Ol S.86E-02 1. 89E-Ol 6.0SE-0l 

1.OOE+OO 1. 46E-Ol 2.llE-Ol 4. 93E-02 1.90E-Ol S.96E-Ol 

2.00E+OO 1. 67E-Ol 1.7.7E-Ol 8'. 72E-03 1.40E-Ol 4. 93E-Ol 

3.00E+OO 1. 69E-Ol 1.60E-Ol 1.S4E-03 7. 68E-02 4.08E-Ol 

4.00E+OO 1.67E-Ol 1.SOE-Ol 2.72E-04 3. 86E-02 3.S6E-Ol 

S.OOE+OO 1. 64E-Ol 1.4SE-Ol 4. 82E-OS 1. 92E-02 3. 28E-Ol 

6.00E+OO 1.60E-Ol 1.4lE-Ol 8.SlE-06 9.9SE-03 3. llE-Ol 

7.00E+OO 1.S7E-Ol 1. 38E-Ol 1.SlE-06 S.SSE-03 3.00E-Ol 

8.00E+OO 1.S3E-Ol 1.36E-Ol 2. 66E-07 3. 47E-03 2. 93E-Ol 

9.00E+OO 1.SOE-Ol 1. 34E-Ol 4.70E-08 2. 46E-03 2. 86E-Ol 

1.OOE+Ol 1.47E-Ol 1. 32E-Ol O.OOE+OO 1.97E-03 2.8lE-Ol 

2.00E+Ol 1.29E-Ol 1.16E-Ol O.OOE+OO 1. 32E-03 2. 46E-Ol 

3.00E+Ol 1. 22E-Ol 1.02E-Ol O.OOE+OO 1.lSE-03 2.2SE-O 

4.00E+Ol 1.20E-Ol 9.0lE-02 O.OOE+OO 1.OOE-03 2. llE-O 

S.OOE+Ol 1.19E-Ol 7. 93E-02 O.OOE+OO 8. 73E-04 1. 99E-Ol 

6.00E+Ol 1.20E-Ol 6. 98E-02 O.OOE+OO 7.60E-04 1.90E-Ol 

7.00E+Ol 1.20E-Ol 6.l4E-02 O.OOE+OO 6.6lE-04 1. 82E-Ol 

8.00E+Ol 1.20E-Ol S.40E-02 O.OOE+OO S.76E-04 1.7SE-Ol 

9.00E+Ol 1.21E-Ol 4.7SE-02 O.OOE+OO S.OlE-04 1. 69E-Ol 

1.OOE+02 1.21E-Ol 4.l8E-02 O.OOE+OO 4. 36E-04 1. 63E-Ol 

2.00E+02 1.18E-Ol 1.lSE-02 O.OOE+OO 1.09E-04 1.29E-Ol 

3.00E+02 1.12E-Ol 3.lSE-03 O.OOE+OO 2. 73E-OS 1.lSE-Ol 

4.00E+02 1.07E-0l 8.SSE-04 O.OOE+OO 6. 82E-06 1.08E-0l 

S.OOE+02 1.03E-Ol 2.3lE-04 O.OOE+OO 1.70E-06 1.03E-Ol 

6.00E+02 9.9SE-02 6.l9E-OS O.OOE+OO 4.26E-07 9. 96E-02 

7.00E+02 9. 66E-02 1.6SE-OS O.OOE+OO 1.07E-07 9. 66E-02 

8.00E+02 9.40E-02 4.40E-06 O.OOE+OO 2.66E-08 9.40E-02 

9.00E+02 9.l7E-02 1.16E-06 O.OOE+OO O.OOE+OO 9.l7E-02 

1.OOE+03 8.96E-02 3.08E-07 O.OOE+OO O.OOE+OO 8.96E-02 

2.00E+03 7. 46E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 46E-02 

4.00E+03 S.69E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.69E-02 

S.OOE+03 S.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.07E-02 

7.00E+03 4.l2E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l2E-02 

8.00E+03 3. 74E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 74E-02 

9.00E+03 3. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-02 

1.OOE+04 3. 13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 13E-02 

2.00E+04 1.39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-02 

B-186 
CLASS V AIW) - 1 MICROB STABLE CALCIOH 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------~--------------------------------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1. 25E-03 1.26E-03 

2.00E-01 1.70E-03 1.85E-03 

3.00E-Ol 2.09E-03 2. 83E-03 

4.00E-Ol 2. 52E-03 4. 62E-03 

5.00E-Ol 2. 95E-03 7.41E-03 

6.00E-ol 3. 38E-03 1. 13E-02 

7.00E-Ol 3.80E-03 1. 64E-02 

8.00E-Ol 4.21E-03 2.26&-02 

9.00E-Ol 4. 62E-03 2. 97E-02 

1.00E+00 5.02E-03 5.02E-03 3. 78E-02 3. 78E-02 

2.00E+00 3.67E-03 8. 68E-03 1.00E-Ol 1.38E-01 

3.00E+00 3.30E-03 1.20E-02 8. 18E-02 2.20E-Ol 

4.00E+00 3.04E-03 1.50E-02 4.81E-02 2.68E-Ol 

5.00E+OO 2.81E-03 1. 78E-02 2. 58E-02 2. 94E-Ol 

6.00E+00 2.60E-03 2.04E-02 1.41E-02 3.08E-Ol 

7.00E+00 2.41E-03 2. 29E-02 8. 34E-03 3. 16E-Ol 

8.00E+00 2. 23E-03 2. 51E-02 5.52E-03 3.21E-01 

9.00E+OO 2.07E-03 2. 72E-02 4.lOE-03 3. 26E-Ol 

1.00E+Ol 1. 92E-03 2.91E-02 3.34E-03 3.29E-01 

2.00E+Ol 9. 48E-04 4.22E-02 1. 71E-03 3. 51E-01 

3.00E+Ol 5. 33E-04 4. 92E-02 1. 19E-03 3.65E-01 

4.00E+Ol 3.50E-04 5. 34E-02 9. 25E-04 3. 75E-Ol 

5.00E+Ol 2. 64E-04 5. 63E-02 7.64E-04 3. 83E-Ol 

6.00E+Ol 2. 19E-04 5. 87E-02 6. 54E-04 3.90E-Ol 

7.00E+Ol 1. 91E-04 6.07E-02 5. 71E-04 3.96E-Ol 

8.00E+Ol 1. 72E-04 6.25E-02 5.03E-04 4.02E-Ol 

9.00E+Ol 1. 57E-04 6. 42E-02 4. 45E-04 4.06E-Ol 

1.00E+02 1. 45E-04 6. 57E-02 3. 95E-04 4. lIE-OI 

2.00E+02 7.02E-05 7. 58E-02 1. 33E-04 4.34E-Ol 

3.00E+02 4.00E-05 8. 11E-02 5. 56E-05 4. 43E-Ol 

4.00E+02 2. 65E-05 8.43E-02 3.04E-05 4. 47E-Ol 

5.00E+02 1. 98E-05 8. 66E-02 2.08E-05 4. 49E-Ol 

6.00E+02 1. 61E-05 8. 84E-02 1.63E-05 4. 51E-Ol 

7.00E+02 1. 38E-05 8.98E-02 1. 38E-05 4. 53E-Ol 

8.00E+02 1. 22E-05 9. 11E-02 1. 22E-05 4. 54E-Ol 

9.00E+02 l.lOE-05 9.23E-02 l.lOE-05 4. 55E:-Ol 

1.00E+03 1.01E-05 , " 9.33E-02 1.01E-05 4. 56E-Ol 

2.00E+03 5. 85E-06 1.0IE-Ol 5. 85E-06 4. 64E-Ol 

4.00E+03 3. 44E-06 1.10E-01 3. 44E-06 4.73E-Ol 

5.00E+03 2. 82E-06 1. 13E-Ol 2. 82E-06 4. 76E-Ol 

7.00E+03 2.01E-06 1. 18E-Ol 2.01E-06 4.80E-Ol 

8.00E+03 1. 74E-06 1.19E-Ol 1. 74E-06 4. 82E-Ol 

1.00E+04 1. 36E-06 1.23E-Ol 1. 36E-06 4. 85E-Ol 

2.00E+04 5. 49E-07 1. 31E-Ol 5. 49E-07 4. 94E-Ol 

B-187 
CLASS V .AHAJ) == 1 KICItON IlALPLIFE== 1.63£+02 DAYS CALCIDH 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES . TRACT BODY· 

1.00E-01 7. 14E-02 2. 76E-01 2. 35E-01 5. 42E-02 6.36E-01 

2.00E-01 8.01E-02 2.6SE-01 1. 97E-01 9. 28E-02 6.3SE-01 

3.00E-01 9. 14E-02 2.SSE-01 1. 66E-01 1. 21E-0l 6. 33E-01 

4.00E-01 1.03E-01 2.47E-01 1. 39E-01 1. 42E-01 6. 31E-01 

5.00E-01 1. 13E-01 2. 39E-01 1. 17E-Ol 1.S9E-01 6. 27E-01 

6.00E-01 1. 21E-0l 2. 32E-01 9. 84E-02 1.71E-OI 6. 23E-01 

7.00E-01 1.29E-0l 2.26E-0l 8. 27E-02 1.79E-01 6. 17E-01 

8.00E-01 1. 35E-OI 2.20E-01 6.9SE-02 1.8SE-Q1 6.lOE-0l 

9.00E-OI 1.41E-01 2.ISE-Ol S.84E-02 1. 88E-0l 6.02E-01 

1.00E+OO 1.4SE-01 2. 1 OE-O 1 4. 91E-02 1. 89E-01 S.94E-01 

2.00E+OO 1. 65E-01 1.76E-0l 8. 64E-03 1. 39E-01 4. 88E-0l 

3.00E+OO 1.67E-Ol 1.S8E-01 1.S2E-03 7.S8E-Q2 4.02E-Ol 

4.00E+OO 1. 64E-01 1.48E-Ol 2. 68E-04 3.80E-02 3.S0E-Ol 

5.00E+OO 1.60E-Ol I. 42E-Ol 4.71E-OS 1. 88E-02 3.2lE-Ol 

6.00E+OO 1. S6E-Ol 1.37E-0l 8.30E-06 9.70E-03 3.03E-01 

7.00E+OO 1.S2E-Ol 1. 34E-01 1. 46E-06 S.39E-03 2.9lE-Ol 

8.00E+OO 1.48E-Ol 1.31E-0l 2. 57E-07 3.3SE-03 2. 83E-Ol 

9.00E+OO 1.44E-Ol 1. 29E-01 4.S3E-08 2. 37E-03 2. 76E-01 

1.OOE+Ol 1.4lE-0l I. 27E-01 O.OOE+OO 1.89E-03 2.69E-0l 

2.00E+Ol 1. 18E-Ol 1.07E~Ol O.OOE+OO 1. 22E-03 2. 26E-OI 

3.00E+OI 1.07E-0l 9.0IE-02 O.OOE+OO 1.01E-03 1. 98E-Ol 

4.00E+01 1.01E-Ol 7.60E-02 O.OOE+OO 8.46E-04 1. 78E-Ol 

S.OOE+01 9.6SE-02 6.41E-02 O.OOE+OO 7.06E-04 1.6lE-OI 

6.00E+01 9.27E-02 5.40E-02 O.OOE+OO S.89E-04 1.47E-Ol 

7.00E+01 8.91E-02 4.S6E-02 O.OOE+OO 4.9IE-04 1.3SE-Ol 

8.00E+Ol 8. 56E-02 3. 84E-02 O.OOE+OO 4.lOE-04 1. 24E-01 

9.00E+Ol 8. 22E-02 3. 24E-02 O.OOE+OO 3. 42E-04 1.15E-Ol 

1.00E+02 7. 89E-02 2. 73E-02 O.OOE+OO 2.8SE-04 1.06E-Ol 

2.00E+02 S.02E-02 4. 92E-03 O.OOE+OO 4. 66E-OS 5.S2E-02 

3.00E+02 3.l3E-02 8.80E-04 O.OOE+OO 7.6lE-06 3. 22E-02 

4.00E+02 1.9SE-Q2 1.S6E-04 O.OOE+OO 1. 24E-06 1.97E-02 

S.OOE+02 1.23E-02 2.7SE-05 O.OOE+OO 2.03E-07 1. 23E-02 

6.00E+02 7.76E-03 4. 83E-06 O.OOE+OO 3. 32E-08 7. 77E-03 

7.00E+02 4. 92E-03 8. 42E-07 O.OOE+OO O.OOE+OO 4. 92E-03 

8.00E+02 3. 13E-03 1.46E-07 O.OOE+OO O.OOE+OO 3. 13E-03 

9.00E+02 2.00E-03 2. 54E-08 O.OOE+OO O.OOE+OO 2.00E-03 

1.OOE+03 I. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.28E-03 

2.00E+03 1.SlE-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.SlE-OS 

3.00E+03 1. 86E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1. 86E-07 

B-188 
CLASS V AHAD = 1 MICRON HALFLIFE= 1.63£+02 DAYS CALCIUM 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -----------------------------~------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.2SE-03 1.26E-03 

2.00E-Ol 1.70E-03 1.8SE-03 

3.00E-Ol 2.09E-03 2. 83E-03 

4.00E-Ol 2.SlE-03 4.6lE-03 

S.OOE-Ol 2. 94E-03 7.40E-03 

6.00E-Ol 3.37E-03 1.13E-02 

7.00E-Ol 3. 79E-03 1. 63E-02 

8.00E-Ol 4.20E-03 2.2SE-02 

9.00E-Ol 4.60E-03 2. 96E-02 

1.OOE+OO S.OOE-03 S.OOE-03 3. 76E-02 3. 76E-02 

2.00E+OO 3. 64E-03 8.6lE-03 9. 92E-02 1.37E-Ol 

3.00E+OO 3. 26E-03 1.18E-02 8.07E-02 2.l7E-Ol 

4.00E+OO 2. 99E-03 1. 48E-02 4.72E-02 2. 63E-Ol 

S.OOE+OO 2.7SE-03 1. 75E-02 2.S3E-02 2. 87E-Ol 

6.00E+OO 2.S4E-03 1.99E-02 1. 38E-02 3.00E-Ol 

7.00E+OO 2. 34E-03 2. 22E-02 8.lOE-03 3.07E-Ol 

8.00E+OO 2.l6E-03 2.43E-02 S.33E-03 3.llE-0l 

9.00E+OO 1. 99E-03 2.6lE-02 3. 94E-03 3.l3E-Ol 

1.OOE+Ol 1. 84E-03 2. 79E-02 3.20E-03 3.lSE-Ol 

2.00E+Ol 8.71E-04 3. 88E-02 1.S7E-03 3. 22E-Ol 

3.00E+Ol 4.70E-04 4. 33E-02 1.OSE-03 3.2lE-Ol 

4.00E+Ol 2.9SE-04 4.S0E-02 7.8lE-04 3.l6E-Ol 

S.OOE+Ol 2.l3E-04 4.SSE-02 6.l8E-04 3.l0E-Ol 

6.00E+Ol 1. 69E-04 4.SSE-02 S.07E-04 3.02E-Ol 

7.00E+Ol 1. 42E-04 4. SlE-02 4.24E-04 2. 94E-Ol 

8.00E+Ol 1.23E-04 4.4SE-02 3.S8E-04 2. 86E-Ol 

9.00E+Ol 1.07E-04 4.38E-02 3.03E-04 2. 77E-Ol 

1.OOE+02 9.4SE-OS 4.29E-02 2.S8E-04 2. 68E-Ol 

2.00E+02 3.00E-OS 3. 24E-02 S.67E-OS 1.8SE-Ol 

3.00E+02 1.12E-OS 2. 26E-02 1. SSE-OS 1. 24E-Ol 

4.00E+02 4. 84E-06 1. S4E-02 S. SSE-06 8.l6E-02 

S.OOE+02 2. 37E-06 1.03E-02 2. 48E-06 S.36E-02 

6.00E+02 1. 26E-06 6.89E-03 1. 27E-06 3.S2E-02 

7.00E+02 7.02E-07 4.'S8E-03 7.0SE-07 2.3lE-02 

8.00E+02 4.0SE-07 3.04E-03 4.06E-07 1.SlE-02 

9.00E+02 2. 39E-07 2.0lE-03 2.39E-07 9.9lE-03 

1.OOE+03 1.43E-07 1. 33E-03 1. 43E-07 6. 49E-03 

B-189 
CLASS 11 AHA» III 1 MICRON UALFLIFE= 4.53E+OO DAYS CALCIUH 47 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7~03E-02 2.72E-Ol 2.31E-Ol 5.34E-02 6.27E-Ol 

2.00E-Ol 7. 77E-02 2. 57E-Ol 1.91E-Ol 9.01E-02 6. 16E-Ol 

3.00E-Ol 8.74E-02 2. 44E-Ol 1. 58E-Ol 1. 16E-Ol 6.06E-Ol 

4.00E-Ol 9. 66E-02 2.33E-Ol 1. 31E-01 1. 34E-Ol 5. 94E-Ol 

5.00E-Ol 1.05E-Ol 2.22E-01 1.09E-Ol 1.47E-Ol 5. 82E-01 

6.00E-Ol 1. 11E-Ol 2. 12E-Ol 9.00E-02 1. 56E-Ol 5.70E-Ol 

7.00E-Ol 1. 16E-Ol 2.04E-Ol 7. 45E-02 1. 62E-Ol 5. 56E-Ol 

8.00E-Ol 1.20E-Ol 1. 95E-Ol 6. 17E-02 1. 64E-Ol 5. 42E-Ol 

9.00E-Ol 1.23E-01 1. 88E-01 .5. 11E-02 1.65E-Ol 5.27E-Ol 

1.00E+00 1. 25E-Ol 1.81E-Ol 4. 23E-02 1. 63E-Ol 5. 12E-Ol 

2.00E+00 1.23E-Ol 1.31E-01 6. 42E-03 1.03E-Ol 3. 63E-Ol 

3.00E+00 1.07E-Ol 1.0IE-Ol 9.74E-04 4. 85E-02 2. 58E-Ol 

4.00E+00 9.07E-02 8. 15E-02 1.48E-04 2.IOE-02 1.93E-Ol 

5.00E+00 7. 63E-02 6. 73E-02 2. 24E-05 8. 96E-03 1. 53E-Ol 

6.00E+00 6.40E-02 5. 62E-02 3.40E-06 3.97E-03 1. 24E-Ol 

7.00E+00 5.37E-02 4. 73E-02 5. 16E-07 1.90E-03 1.03E-Ol 

8.00E+00 4.50E-02 4.00E-02 7. 82E-08 1.02E-03 8.60E-02 

9.00E+00 3. 78E-02 3. 38E-02 1. 19E-08 6.21E-04 7. 23E-02 

1.00E+Ol 3.18E-02 2. 86E-02 O.OOE+OO 4. 26E-04 6.09E-02 

2.00E+Ol 6.03E-03 5.45E-03 O.OOE+OO 6.20E-05 1. 15E-02 

3.00E+Ol 1. 24E-03 1.04E-03 O.OOE+OO 1. 17E-05 2. 29E-03 

4.00E+Ol 2. 63E-04 1. 98E-04 O.OOE+OO 2.20E-06 4. 63E-04 

5.00E+Ol 5. 68E-05 3.77E-05 O.OOE+OO 4. 15E-07 9. 49E-05 

6.00E+Ol 1. 23E-05 7. 18E-06 O.OOE+OO 7. 83E-08 1.96E-05 

7.00E+Ol 2. 68E-06 1. 37E-06 O.OOE+OO 1. 47E-08 4.06E-06 

8.00E+Ol 5.81E-07 2. 61E-07 O.OOE+OO O.OOE+OO 8.42E-07 

9.00E+Ol 1. 26E-07 4. 97E-08 O.OOE+OO O.OOE+OO 1. 76E-07 

1.00E+02 2. 73E-08 O.OOE+OO O.OOE+OO O.OOE+OO 2. 73E-08 

B-190 
CLASS V AHAD - 1 KICROH BALFLIFE- 4.53£+00 DAYS CA.LCIUK 47 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 1. 23E-03 1. 24E-03 

2.00E-Ol 1.6SE-03 1.79E-03 

3.00E-Ol 2.00E-03 2.7lE-03 

4.00E-Ol 2. 37E-03 4. 34E-03 

S.OOE-Ol 2.73E-03 6.B7E-03 

6.00E-Ol 3.0BE-03 1.03E-02 

7.00E-Ol 3. 42E-03 1.47E-02 

8.00E-Ol 3. 73E-03 2.00E-02 

9.00E-Ol 4.03E-03 2.S9E-02 

1.OOE+OO 4.3lE-03 4.3lE-03 3. 24E-02 3. 24E-02 

2.00E+OO 2.70E-03 6.40E-03 7.37E-02 1.02E-Ol 

3.00E+OO 2.09E-03 7.SBE-03 S.17E-02 1. 39E-Ol 

4.00E+OO 1.6SE-03 8.lSE-03 2.6lE-02 1.4SE-Ol 

S.OOE+OO 1.3lE-03 8.30E-03 1.20E-02 1.37E-Ol 

6.00E+OO 1.04E-03 B.16E-03 S.64E-03 1. 23E-Ol 

7.00E+OO B.26E-04 7.B3E-03 2. 86E-03 1.08E-Ol 

B.OOE+OO 6.S6E-04 7.3BE-03 1. 62E-03 9.4SE-02 

9.00E+OO S.22E-04 6.8SE-03 1.03E-03 B.2lE-02 

1.OOE+Ol 4.lSE-04 6. 29E-03 7. 24E-04 7.l2E-02 

2.00E+Ol 4.44E-OS 1.9BE-03 B.OOE-OS 1. 64E-02 

3.00E+Ol S.4lE-06 4. 99E-04 1.2lE-OS 3.70E-03 

4.00E+Ol 7.70E-07 1.17E-04 2.03E-06 B.24E-04 

S.OOE+Ol 1.26E-07 2.6BE-OS 3.64E-07 1.B2E-04 

6.00E+Ol 2.2SE-OB 6.0SE-06 6. 74E-OB 4.02E-OS 

B-19l 
CLASS V .AHAD ... 1 HICR.ON STABLE TITAtUUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 7.l0E-02 2. 76E-Ol 2.3SE-Ol S.7lE-02 6. 39E-Ol 

2.00E-Ol 7.l4E-02 2.6SE-Ol I. 97E-Ol I.OSE-Ol 6. 39E-Ol 

3.00E-Ol 7.18E-02 2.S6E-Ol 1. 66E-Ol 1.4SE-0l 6. 38E-Ol 

4.00E-Ol 7.22E-D2 2.47E-Ol 1. 39E-Ol 1. 78E-Ol 6.37E-Ol 

S.OOE-Ol 7. 26E-02 2.40E-OI 1.17E-Ol 2.04E-OI 6. 34E-0l 

6.00E-Ol 7.30E-02 2. 33E-Ol 9. 86E-02 2.2SE-Ol 6.30E-Ol 

7.00E-0l 7. 33E-02 2. 27E-OI 8. 29E-02 2.4lE-0l 6. 24E-OI 

8.00E-Ol 7.36E-02 2.2lE-Ol 6. 97E-02 2.S2E-Ol 6.l6E-Ol 

9.00E-Ol 7. 39E-02 2.l6E-Ol S.86E-02 2.S9E-Ol 6.07E-0l 

1.OOE+OO 7.4lE-02 2.llE-Ol 4. 93E-02 2. 63E-Ol S.97E-Ol 

2.00E+OO 7.S6E-02 1.77E-Ol 8. 72E-03 2.0lE-0l 4.63E-Ol 

3.00E+OO 7.63E-02 1.60E-Ol 1.S4E-03 1.12E-Ol 3.S0E-Ol 

4.00E+OO 7. 68E-02 1.SOE-Ol 2. 72E-04 S.66E-02 2. 84E-Ol 

S.OOE+OO 7. 73E-02 1.4SE-Ol 4. 82E-OS 2. 82E-02 2.S0E-Ol 

6.00E+OO 7.77E-02 1.4lE-Ol 8.SlE-06 1.4SE-02 2. 33E-0l 

7.00E+OO 7. 82E-02 1. 38E-Ol 1.SlE-06 8.0SE-03, 2. 24E-Ol 

8.00E+OO 7. 86E-02 1. 36E-Ol 2. 66E-07 4. 99E-03 2.l9E-Ol 

9.00E+OO 7.90E-02 ' 1.34E-Ol 4.70E-08 3.SlE-03 2.l6E-Ol 

1.OOE+Ol 7. 94E-02 1.32E-Ol O.OOE+OO 2. 79E-03 2.l4E-Ol 

2.00E+Ol 8.30E-02 ' 1.16E-Ol O.OOE+OO 1.8SE-03 2.0lE-Ol 

3.00E+Ol 8. 63E-02 1.02E-Ol O.OOE+OO 1.6lE-03 1.90E-Ol 

4.00E+Ol 8.90E-02 9. OlE-02 O.OOE+OO 1.40E-03 1.80E-Ol 

S.OOE+Ol 9.l4E-02 7. 93E-02 O.OOE+OO 1. 22E-03 1. 72E-Ol 

6.00E+0l 9. 34E-02 6. 98E-02 O.OOE+OO 1.06E-03 1. 64E-Ol 

7.00E+Ol 9.S2E-02 6.14E-02 O.OOE+OO 9.27E-04 1.S7E-Ol 

8.00E+Ol 9. 66E-02 S.40E-02 O.OOE+OO 8.07E-04 1.SlE-Ol 

9.00E+Ol 9.77E-02 4.7SE-02 O.OOE+OO 7.02E-04 1.46E-Ol 

1.OOE+02 9. 86E-02 4.l8E-02 O.OOE+OO 6.l2E-04 1.4lE-Ol 

2.00E+02 9. 88E-02 1.lSE-02 O.OOE+OO 1.S3E-04 1.lOE-Ol 

3.00E+02 9.lSE-02 3.lSE-03 O.OOE+OO 3. 82E-OS 9.47E-02 

4.00E+02 8. 26E-02 8.SSE-04 O.OOE+OO 9. S6E-06 8. 34E-02 

S.OOE+02 7. 39E-02 2.3lE-04 O.OOE+OO 2. 39E-06 7.4lE-02 

6.00E+02 6.S9E-02 6.l9E-OS O.OOE+OO S.97E-07 6.60E-02 

7.00E+02 S.87E-02 1.6SE-OS O.OOE+OO 1. 49E-07 S.88E-02 

8.00E+02 S.23E-02 4.40E-06 O.OOE+OO 3.73E-08 S.23E-02 

9.00E+02 4. 66E-02 1.16E-06 O.OOE+OO O.OOE+OO 4. 66E-02 

I.OOE+03 4.ISE-02 3.08E-07 O.OOE+OO O.OOE+OO 4.ISE-02 

2.00E+03 1.3IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.3IE-02 

4.00E+03 1.30E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-03 

S.OOE+03 4.09E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4.09E-04 

6.00E+03 1.29E-04 O.OOE+OO O.OOE+OO O.OOE+OO I. 29E-04 

7.00E+03 4.06E-OS O.OOE+OO O.OOE+OO O.OOE+OO 4.06E-OS 

8.00E+03 I. 28E-OS O.OOE+OO O.OOE+OO O.'OOE+OO 1. 28E-OS 

9.00E+03 4.03E-06 O.OOE+OO O.OOE+OO O.OOE+OO 4.03E-06 

1.OOE+04 1.27E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.27E-06 

B-192 
CLASS V AMAD = 1 MICRON STABLB TITANIUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7.02E-06 8.09E-06 

2.00E-Ol 1. 53E-05 1. 64E-04 

3.00E-Ol 2. 35E-05 8. 27E-04 

4.00E-Ol 3. 18E-05 2.41E-03 

5.00E-Ol 4.02E-05 5. 26E-03 

6.00E-Ol 4. 86E-05 9.57E-03 

7.00E-Ol 5. 71E-05 1.54E-02 

8.00E-Ol 6. 56E-05 2. 29E-02 

9.00E-Ol 7.41E-05 3. 17E-02 

1.00E+00 8. 26E-05 8. 26E-05 4. 19E-02 4. 19E-02 

2.00E+00 8. 66E-05 1. 69E-04 1.34E-01 1.76E-Ol 

3.00E+00 8. 77E-05 2. 57E-04 1. 13E-Ol 2. 89E-Ol 

4.00E+00 8. 84E-05 3. 45E-04 6.57E-02 3. 55E-Ol 

5.00E+00 8.90E-05 4. 34E-04 3. 38E-02 3.89E-Ol 

6.00E+00 8. 95E-05 5. 24E-04 1. 69E-02 4.06E-Ol 

7.00E+00 9.00E-05 6. 14E-04 8. 68E-03 4. 14E-Ol 

8.00E+00 9.05E-05 7.04E-04 4. 78E-03 4. 19E-Ol 

9.00E+00 9.IOE-05 7. 95E-04 2. 93E-03 4. 22E-Ol 

1.00E+Ol 9. 14E-05 8. 87E-04 2.05E-03 4. 24E-Ol 

2.00E+Ol 9. 57E-05 1. 83E-03 1.07E-03 4. 36E-Ol 

3.00E+Ol 9. 94E-05 2.80E-03 9. 35E-04 4. 46E-Ol 

4.00E+Ol 1.03E-04 3. 82E-03 8. 14E-04 4. 55E-Ol 

5.00E+Ol 1.05E-04 4. 86E-03 7.08E-04 4. 62E-01 

6.00E+Ol 1.08E-04 5. 93E-03 6. 17E-04 4. 69E-Ol 

7.00E+Ol 1.IOE-04 7.02E-03 5. 37E-04 4. 75E-Ol 

8.00E+Ol 1. 11E-04 8. 12E-03 4. 67E-04 4.80E-Ol 

9.00E+Ol 1. 13E-04 9. 25E-03 4.07E-04 4. 84E-Ol 

1.00E+02 1. 14E-04 1.04E-02 3. 54E-04 4.88E-Ol 

2.00E+02 1.14E-04 2. 19E-02 8. 86E-05 5.07E-Ol 

3.00E+02 1.06E-04 3. 29E-02 2. 21E-05 5. 12E-Ol 

4.00E+02 9. 54E-05 4.30E-02 5. 53E-06 5. 13E-Ol 

5.00E+02 8. 54E-05 5.20E-02 1. 38E-06 5. 13E-Ol 

6.00E+02 7. 62E-05 6.01E-02 3.46E-07 5. 13E-Ol 

7.00E+02 6. 79E-05 6. 73E-02 8. 65E-08 5. 13E-Ol 

8.00E+02 6.05E-05 7. 37E-02 2. 16E-08 5. 13E-Ol 

9.00E+02 5. 39E-05 7. 94E-02 O.OOE+OO 5. 13E-Ol 

1.00E+03 4.80E-05 8. 45E-02 O.OOE+OO 5. 13E-01 

2.00E+03 1. 51E...,05 1. 13E-01 O.OOE+OO 5. 13E-Ol 

4.00E+03 1.50E-06 1. 25E-Ol O.OOE+OO 5. 13E-Ol 

5.00E+03 4. 73E-07 1. 26E-Ol O.OOE+OO 5. 13E-Ol 

7.00E+03 4.70E-08 1. 26E-Ol O.OOE+OO 5. 13E-Ol 

8.00E+03 1. 48E-08 1. 26E-01 O.OOE+OO 5. 13E-Ol 

B-193 
CLASS W MAD = 1 KICilON BALFLIFE= 3.30£+02 DAYS VANADIUM 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 6.06E-02 2. 76E-Ol 2. 35E-Ol 5.71E-02 6. 29E-Ol 

2.00E-Ol 5. 14E-02 2. 65E-Ol 1. 97E-Ol 1.05E-Ol 6. 19E-Ol 

3.00E-Ol 4. 45E-02 2. 56E-Ol 1. 66E-Ol 1. 45E-Ol 6. l1E-01 

4.00E-Ol 3. 93E-02 2. 47E-Ol 1. 39E-01 1. 78E-Ol 6.03E-Ol 

5.00E-Ol 3. 54E-02 2. 39E-Ol 1. 17E-Ol 2.04E-Ol 5. 96E-Ol 

6.ooE-01 3. 25E-02 2. 32E-Ol 9. 85E-02 2. 25E-Ol 5. 88E-Ol 

7.00E-Ol 3.02E-02 2. 26E-Ol 8.28E-02 2.40E-Ol 5.80E-Ol 

8.00E-Ol 2. 85E-02 2.20E-Ol 6. 96E-02 2. 52E-Ol 5.70E-Ol 

9.00E-Ol 2. 72E-02 2. 15E-01 5.85E-02 2. 59E-Ol 5.60E-Ol 

1.00E+00 2. 62E-02 2.10E-Ol 4. 92E-02 2. 62E-ol 5. 48E-ol 

2.00E+00 2. 32E-02 1.77E-Ol 8. 68E-03 2.01E-01 4.09E-Ol 

3.00E+00 2.30E-02 1. 59E-Ol 1. 53E-03 l.llE-OI 2. 95E-Ol 

4.00E+00 2.31E-02 1.49E-Ol 2.70E-04 5.61E-02 2. 28E-Ol 

5.ooE+00 2. 32E-02 1. 43E-Ol 4.77E-05 2. 79E-02 1. 94E-Ol 

6.00E+00 2. 33E-02 1. 39E-Ol 8. 41E-06 1. 43E-02 1. 77E-Ol 

7.00E+00 2. 34E-02 1. 36E-Ol 1. 48E-06 7. 93E-03 1.67E-ol 

8.00E+00 2. 35E-02 1. 34E-01 2. 62E-07 4.90E-03 1. 62E-Ol 

9.00E+00 2. 36E-02 1.31E-Ol 4. 62E-08 3. 45E-03 1. 58E-Ol 

1.00E+Ol 2. 37E-02 1.29E-Ol O.OOE+OO 2.73E-03 1. 56E-Ol 

2.00E+Ol 2. 45E-02 I.UE-Ol O.OOE+OO 1. 78E-03 1. 38E-Ol 

3.00E+Ol 2. 51E-02 9.61E-02 O.OOE+OO 1. 52E-03 1.2 

4.00E+Ol 2. 56E-02 8. 28E-02 O.OOE+OO 1.29E-03 1.IOE-O 

5.00E+Ol 2.60E-02 7. 14E-02 O.OOE+OO 1.10E-03 9. 85E-02 

6.00E+Ol 2. 63E-02 6. 15E-02 O.OOE+OO 9. 39E-04 8. 87E-{) 2 

7.00E+Ol 2. 64E-02 5.30E-02 O.OOE+OO 8.00E-04 8.02E-02 

8.00E+Ol 2. 65E-02 4. 56E-02 O.OOE+OO 6. 82E-04 7.28~-02 

9.00E+Ol 2. 65E-02 3. 93E-02 O.OOE+OO 5. 81E-04 6. 64E-02 

1.00E+02 2. 64E-02 3. 39E-02 O.OOE+OO 4. 96E-04 6.07E-02 

2.00E+02 2. 35E-02 7. 57E-03 O.OOE+oo 1.00E-04 3. 12E-02 

3.00E+02 1. 9~1):-02 1. 68E-03 O.OOE+OO 2.04E-05 2. 12E-02 

4.00E+02 1.59E-02 3. 69E-04 O.OOE+OO 4. 12E-06 1. 62E-02 

5.00E+02 1. 28E-02 8.07E-05 O.OOE+OO 8. 36E-07 1. 29E-02 

6.00E+02 1.03E-02 1. 76E-05 O.OOE+oo 1.69E-07 1.03E-02 

7.00E+02 8.30E-03 3.80E-06 O.OOE+OO 3. 43E-08 8.30E-03 

8.00E+02 6. 68E-03 8. 19E-07 O.OOE+oo O.OOE+OO 6. 68E-03 

9.00E+02 5. 38E-03 1. 76E-07 O.OOE+OO O.OOE+OO 5. 38E-03 

1.00E+03 4. 33E-03 3.77E-08 O.OOE+OO O.OOE+OO 4. 33E-03 

2.00E+03 4. 94E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 94E-04 

3.00E+03 5. 65E-05 O.OOE+OO O.OOE+oo O.OOE+OO 5. 65E-05 

4.00E+03 6. 45E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6. 45E-06 

5.00E+03 7. 36E-07 O.OOE+OO O.OOE+oo O.OOE+oo 7. 36E-07 

6.00E+03 8.41E-08 O.OOE+OO O.OOE+OO O.OOE+OO 8.41E-08 

B-194 
CLASS W- AHAB - 1 MICRON HALFLIFE- 3.30E+02 DAYS VANADIUM 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ---~------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.05E-02 8.09E-06 

2.00E-ol 2.00E-02 1. 63E-04 

3.00E-Ol 2. 73E-02 8. 26E-04 

4.00E-Ol 3. 29E-02 2. 41E-03 

5.00E-Ol 3. 72E-02 5. 25E-03 

6.00E-Ol 4.05E-02 9. 56E-03 

7.00E-Ol 4. 31E-02 1. 54E-02 

8.00E-Ol 4. 51E-02 2. 28E-02 

9.00E-Ol 4. 67E-02 3. 17E;"02 

1.00E+00 4. 79E-02 4. 79E-02 4. 18E-02 4. 18E-02 

2.00E+00 4. 46E-03 5. 23E-02 1. 34E-Ol 1. 75E-Ol 

3.00E+00 8. 98E-04 5.30E-02 1. 12E-Ol 2. 87E-Ol 

4.00E+00 4.90E-04 5. 34E-02 6. 52E-02 3.52E-Ol 

5.00E+00 4.05E-04 5. 37E-02 3. 34E-02 3.85E-Ol 

6.00E+00 3. 74E-04 5.40E-02 1. 67E-02 4.00E-Ol 

7.00E+00 3. 59E-04 5. 42E-02 8.56E-03 4.08E-Ol 

8.00E+00 3. 49E-04 5. 45E-02 4.70E-03 4. 12E-Ol 

9.00E+00 3. 43E-04 5. 47E-02 2. 88E-03 4. 14E-Ol 

1.00E+Ol 3. 37E-04 5. 49E-02 2.00E-03 4. 15E-Ol 

2.00E+Ol 2. 99E-04 5. 69E-02 1.03E-03 4. 18E-Ol 

3.00E+Ol 2. 66E-04 5. 85E-02 8.78E-04 4. 19E-Ol 

4.00E+Ol 2. 36E-04 5. 97E-02 7. 48E-04 4. 18E-Ol 

5.00E+Ol 2.09E-04 6.07E-02 6. 38E-04 4. 16E-Ol 

6.00E+Ol 1. 85E-04 6. 14E-02 5. 44E-04 4.13E-Ol 

7.00E+Ol 1. 63E-04 6. 18E-02 4. 63E-04 4.IOE-Ol 

8.00E+Ol 1. 44E-04 6.20E-02 3. 95E-04 4.05E-Ol 

9.00E+Ol 1. 27E-04 6. 21E-02 3. 37E-04 4.0lE-01 

1.00E+02 1. 12E-04 6.20E-02 2. 87E-04 3. 95E-01 

2.00E+02 3.IOE-05 5. 58E-02 5. 82E-05 3. 33E-Ol 

3.00E+02 8. 71E-06 4. 67E-02 1. 18E-05 2. 72E-Ol 

4.00E+02 2. 88E-06 3.83E-02 2. 39E-06 2.21E-Ol 

5.00E+02 1.30E-06 3. 12E-02 4. 84E-07 1. 79E-Ol 

6.00E+02 8. 11E-07 2. 54E-02 9. 81E-08 1.46E-Ol 

7.00E+02 5. 97E-07 2.07E-02 ·1.99E-08 1. 18E-Ol '. 8.00E+02 4. 68E-07 1.68E-02 O.OOE+OO 9. 56E-02 

9.00E+02 3. 74E-07 1. 37E-02 O.OOE+OO 7.75E-02 

1.00E+03 3.00E-07 1. l1E-02 O.OOE+OO 6. 28E-02 

2.00E+03 3. 43E-08 1. 39E-03 O.OOE+OO 7.69E-03 

B-195 
ClASS W AHAD ... 1 HICKOK BALFLU'E... 2.77E+Ol DAYS CHIlOHIUH .51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.S9E-02 2. 76E-01 2. 34E-01 S.62E-02 6.3SE-Ol 

2.00E-01 6.S7E-02 2. 64E-01 1. 96E-01 1.01E-01 6.30E-01 

3.00E-01 6. 96E-02 2.S4E-01 1.6SE-Ol 1.37E-01 6.2SE-01 

4.00E-01 7.07E-02 2.4SE-01 +.3SE-01 1.66E-01 6.20E-Ol 

S.OOE-Ol 7.1SE-02 2. 37E-01 ~.16E-01 1.S9E-01 6.l3E-Ol 

6.00E-01 7.26E-02 2. 29E-01 9. 72E-02 2.06E-01 6.0SE-ol 

7.00E-Ol 7. 31E-02 2. 23E-01 S.lSE-02 2. 19E-Ol S.96E-01 

S.OOE-01 7. 34E-02 2. 16E-0l 6.S4E-02 2.2SE-01 S.S6E-01 

9.00E-01 7.3SE-02 2.11E-0l S.73E-02 2.33E-0l S.74E-01 

1.OOE+OO 7. 34E-02 2.06E-01 4.S1E-02 2.3SE-01 S.-62E-01 

2.00E+OO 6.SSE-02 1. 69E-01 S.29E-03 1.73E-01 4. 19E-01 

3.00E+OO 6. 29E-02 1.4SE-01 1. 43E-03 9. 36E-02 3.06E-01 

4.00E+OO S.SlE-02 1. 36E-01 2. 46E-04 4.60E-02 2.40E-01 

S.OOE+OO S.40E-02 1.2SE-01 4.2SE-OS 2. 24E-02 2.04E-01 

6.00E+OO S.02E-02- 1.21E-01 7.33E-06 1. 12E-02 1.S3E-01 

7.00E+OO 4. 69E-02 1. 16E-01 1. 26E-06 6.09E-03 1. 69E-01 

S.OOE+OO 4.39E-02 1. 11E-0l 2.1SE-07 3. 69E-03 1.S9E-01 

9.00E+OO 4. 12E-02 1.07E-01 3.7SE-OS 2.S4E-03 1.SlE-01 

1.00E+01 3.SSE-02 1.03E-01 O.OOE+OO 1. 97E-03 1.44E-01 

2.00E+Ol 2.3SE-02 .7.0SE-02 O.OOE+OO 1.02E-03 9.S3E-02 

3.00E+01 1.66E-02 4.S3E-02 O.OOE+OO 6. 94E-04 6. S6E-02 

4.00E+01 1. 22E-02 3. 31E-02 O.OOE+OO 4.70E-04 4. 

S. OO~+Ol 9. 12E-03 2.27E-02 O.OOE+OO 3. 19E-04 3.21E-02 

6.00E+01 6.S4E-03 1.SSE-02 O.OOE+OO 2. 16E-04 2. 26E-02 

7.00E+01 S.l3E-03 1.07E-02 O.OOE+OO 1. 47E-04 1.S9E-02 

S.OOE+01 3.S4E-03 7.30E-03 O.OOE+OO 9.93E-OS 1. 12E-02 

9.00E+01 2.SSE-03 S.OOE-03 O.OOE+OO 6. 73E-OS 7. 94E-03 

1.00E+02 2.1SE-03 3. 42E-03 O.OOE+OO 4.S6E-OS S.62E-03 

2.00E+02 1. 17E-04 7. 74E-OS O.OOE+OO 9.3SE-07 1.9SE-04 

3.00E+02 6.S4E-06 1. 73E-06 O.OOE+OO 1. 91E-OS S.29E-06 

4.00E+02 3.99E-07 3. SSE-OS O.OOE+OO O.OOE+OO 4.3SE-07 

S.OOE+02 2. 66E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2. 66E-OS 

B-196 
CLASS V AMAD == 1 MICRON BALPLIFE- 2.77£+01 DAYS CBKOHIUH 51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-OI 2.6SE-03 7. 99E-06 

2.00E-Ol 5. 54E-03 1.60E-04 

3.00E-Ol S.20E-03 7.9SE-04 

4.00E-Ol 1.07E-02 2.31E-03 

5.00E-0l 1.31E-02 4.9SE-03 

6.00E-Ol 1. 53E-02 S.99E-03 I 7.00E-Ol 1.75E-02 1.44E-02 

S.OOE-Ol 1. 95E-02 2.l2E-02 

9.00E-O! 2. 14E-02 2. 92E-02 

1.OOE+OO 2.3lE-02 2.3lE-02 3.S3E-02 3.S3E-02 

2.00E+OO 1.2SE-02 3. 54E-02 1.17E-0l 1. 54E-Ol 

3.00E+OO 7.l6E-03 4.l6E-02 9.4SE-02 2. 45E-Ol 

4.00E+OO 4.7SE-03 4. 54E-02 5. 35E-02 2.93E-Ol 

5.00E+OO 3. 72E-03 4.S0E-02 2.6SE-02 3.l2E-Ol 

6.00E+OO 3.l2E-03 4. 99E-02 1.3lE-02 3.17E-0l 

7.00E+OO 2.71E-03 5.l4E-02 6. 55E-03 3.16E-Ol 

S.OOE+OO 2.3SE-03 5.25E-02 3. 53E-03 3.l2E-0l 

9.00E+OO 2.l2E-03 5. 33E-02 2.UE-03 3.06E-Ol 

1.OOE+Ol I.S9E-03 5. 39E-02 1. 44E-03 3.00E-Ol 

2.00E+Ol 7. 13E-04 5.lSE-02 5. 92E-04 2.40E-Ol 

3.00E+Ol 3. 56E-04 4. 46E-02 4.01E-04 1.9lE-Ol 

4.00E+Ol 2.lSE-04 3. 72E-02 2. 72E-04 1. 52E-Ol 

5.00E+Ol 1.47E-04 3.05E-02 1.S4E-04· 1.20E-Ol 

6.00E+Ol 1.04E-04 2.4SE-02 1. 25E-04 9.50E-02 

7.00E+Ol 7.3SE-05 2.0lE-02 S.47E-05 7. 49E-02 

S.OOE+Ol 5.2SE-05 1. 62E-02 5. 74E-05 5.S9E-02 

9.00E+Ol 3.7SE-05 1.30E-02 3.S9E-05 4. 63E-02 

1.00E+02 2.7lE-05 1.04E-02 2.ME-05 3.63E-02 

2.00E+02 9. 59E-07 1.OOE-03 5.40E-07 3.09E-03 

3.00E+02 3. 42E-OS S.74E-05 1.UE-OS 2. 56E-04 

B-197 
CLASS W AHAD == 1 HICR.ON STABLE CIIltOHIUH 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 91E-02 2. 76E-01 2. 35E-01 5. 64E-02 6. 36E-01 

2.00E-01 6. 91E-02 2. 65E-01 1.97E-01 1.02E-01 6. 33E-01 

3.00E-01 7.01E-02 2.'56E-01 1.66E-01 1. 38E-01 6.30E-01 

4.00E-01 7. 14E-02 2. 47E-01 1. 39E-01 1. 68E-01 6. 26E-01 

5.00E-01 7. 27E-02 2.40E-01 1. 17E-01 1. 91E-01 6.21E-01 

6.00E-01 7. 37E-02 2. 33E-01 9. 86E-02 2.09E-01 6. 14E-01 

7.00E-01 7.44E-02 2. 27E-01 8. 29E-02 2. 23E-01 6.07E-01 

8.00E-01 7.49E-02 2. 21E-01 6. 97E-02 2. 32E-01 5. 98E-01 

9.00E-01 7. 52E-02 2. 16E-01 5. 86E-02 2. 38E-01 5. 87E-01 

1.00E+00 7. 53E-02 2. 11E-01 4. 93E-02 2.41E-01 5. 76E-01 

2.00E+00 7. 21E-02 1.77E-01 8. 72E-03 1. 82E-01 4.40E-01 

3.00E+00 6.78E-02 ' 1.60E-01 1. 54E-03 1.01E-01 3.30E-01 

4.00E+00 6. 43E-02 1.50E-01 2.72E-04 5.09E-02 2. 66E-01 

5.00E+00 6. 11E-02 1. 45E-01 4. 82E-05 2. 53E-02 2. 31E-01 

6.00E+00 5. 84E-02 1.41E-01 8. 51E-06 1. 31E-02 2. 12E-01 

7.00E+OO 5. 59E-02 1. 38E-01 1. 51E-06 7. 26E-03 2.01E-01 

8.00E+00 5.36E-02 1.36E-01 2.66E-07 4.51E-03 1. 94E-01 

9.00E+00 5. 16E-02 1. 34E-01 4.70E-08 3. 18E-03 1. 89E-01 

1.00E+01 4.98E-02 1. 32E-01 O.OOE+OO 2. 53E-03 1. 84E-01 

2.00E+01 3. 92E-02 1. 16E-01 O.OOE+OO 1. 69E-03 1. 57E-01 

3.00E+01 3. 52E-02 1.02E-01 O.OOE+OO 1. 47E-03 1. 39E-0 

4.00E+01 3. 32E-02 9.01E-02 O.OOE+OO 1. 28E-03 1. 25E-0 

5.00E+01 3. 19E-02 7.93E-02 O.OOE+OO 1. 11E-03 1. 12E-0 

6.00E+01 3.07E-02 6. 98E-02 O.OOE+OO 9.70E-04 1.01E-01 

7.00E+01 2. 96E-02 6. 14E-02 O.OOE+OO 8. 44E-04 9. 18E-02 

8.00E+01 2. 84E-02 5.40E-02 O.OOE+OO 7. 35E-04 8. 32E-02 

9.00E+01 2. 74E-02 4.75E-02 O.OOE+oo 6.40E-04 7. 55E-02 

1.00E+02 2. 63E-02 4. 18E-02 O.OOE+OO 5. 57E-04 6. 86E-02 

2.00E+02 1. 74E-02 1. 15E-02 O.OOE+OO 1. 39E-04 2.90E-02 3~00E+02 1. 19E-02 3. 15E-03 O.OOE+OO 3. 48E-05 1. 51E-02 

4.00E+02 8. 87E-03 8. 55E-04 O.OOE+OO 8.7lE-06 9.73E-03 

5.00E+02 7.21E-03 2. 31E-04 O.OOE+OO 2. 18E-06 7. 45E-03 

6.00E+02 6. 25E-03 6. 19E-05 O.OOE+OO 5. 44E-07 6. 31E-03 

7.00E+02 5. 62E-03 1. 65E-05 O.OOE+OO 1. 36E-07 5. 63E-03 

8.00E+02 5. 15E-03 4.40E-06 O.OOE+OO 3.40E-08 5. 15E-03 

9.00E+02 4. 76E-03 1. 16E-06 O.OOE+OO O.ooE+OO 4. 76E-03 

1.00E+03 4. 43E-03 3.08E-07 O.OOE+OO O.OOE+oo 4. 43E-03 

2.00E+03 2. 21E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 21E-03 

4.00E+03 5.52E-04 O.OOE+OO O.OOE+oo O.OOE+oo 5. 52E-04 

5.ooE+03 2. 76E-04 O.ooE+OO O.OOE+OO O.OOE+OO 2. 76E-04 

7.00E+03 6.90E-05 O.OOE+OO O.OOE+OO O.OOE+oo 6.90E-05 

8.00E+03 3. 45E-05 O.ooE+OO O.OOE+OO O.ooE+OO 3. 45E-05 

1.00E+04 8. 63E-06 O.OOE+OO O.OOE+oo O.ooE+oo 8. 63E";06 

B-198 
ClASS W AHA» = 1 MICRON STABLE amOMIUM 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 2.6SE-03 S.OIE-06 

2.00E-OI S.S6E-03 1.60E-04 

3.00E-0l S.26E-03 S.04E-04 

4.00E-OI I.OSE-02 2. 33E-03 

S.OOE-OI 1.33E-02 S.04E-03 

6.00E-Ol 1. S6E-02 9.13E-03 

7.00E-Ol 1.7SE-02 1. 47E-02 

S.OOE-OI 1. 99E-02 2.16E-02 

9.00E-Ol 2.lSE-02 2.9SE-02 

1.OOE+OO 2. 37E-02 2. 37E-02 3. 93E-02 3. 93E-02 

2.00E+OO 1.3SE-02 3. 72E-02 1. 23E-OI 1.62E-OI 

3.00E+OO 7.7lE-03 4. 49E-02 I.02E-Ol 2. 64E-Ol 

4.00E+OO S.29E-03 S.02E-02 S.92E-02 3.23E-OI 

S.OOE+OO 4.2IE-03 S.44E-02 3.04E-02 3. 54E-Ol 

6.00E+OO 3. 62E-03 S.SOE-02 1.S2E-02 3. 69E-OI 

7.00E+OO 3. 22E-03 6.12E-02 7.SlE-03 3. 77E-ol 

S.OOE+OO 2.9lE-03 6. 42E-02 4.3lE-03 3. SIE-Ol 

9.00E+OO 2.6SE-03 6.6SE-02 2.6SE-03 3.S4E-OI 

I.OOE+Ol 2. 42E-03 6. 92E-02 I.SSE-03 3.SSE-Ol 

2.00E+OI 1.lSE-03 S.SSE-02 9.77E-04 3. 97E-OI 

3.00E+OI 7. SSE-04 9. 45E-02 S.SOE-04 4.06E-Ol 

4.00E+Ol S.93E-04 I.OIE-Ol 7.40E-04 4.13E-OI 

S.OOE+Ol S.lSE-04 I.07E-0l 6. 44E-04 4.20E-Ol 

6.00E+Ol 4.6SE-04 1.11E-Ol 5.6lE-04 4. 26E-OI 

7.00E+Ol 4.2SE-04 1.16E-OI 4.SSE-04 4. 32E-OI 

S.OOE+OI 3.9lE-04 1.20E-Ol 4.2SE-04 4. 36E-OI 

9.00E+Ol 3.60E-04 1.24E-OI 3.70E-04 4.40E-OI 

I.OOE+02 3.3IE-04 1. 27E-OI 3. 22E-04 4. 43E-Ol 

2.00E+02 1. 43E-04 1.49E-Ol S.OSE-OS 4.6lE-Ol 

3.00E+02 6. 22E-OS I.S9E-Ol 2.0lE-OS 4.6SE-Ol 

4.00E+02 2.S3E-05 1. 63E-Ol S.03E-06 4. 66E-Ol 

S.OOE+02 1.41E-OS 1.6SE-Ol 1. 26E-06 4. 66E-Ol 

6.00E+02 S.llE-06 1. 66E-Ol 3.l4E-07 4.66E-Ol 

7 .. 00E+02 5. 46E-06 1.67E-OI 7.S6E-OS 4. 66E-Ol 

S.OOE+02 4.22E-06 1.6SE-OI 1.97E-OS 4.66E-Ol 

9.00E+02 3.SSE-06 1.6SE-Ol O.OOE+OO 4. 66E-Ol 

1.OOE+03 3.1SE-06 1.6SE-Ol O.OOE+OO 4. 66E-Ol 

2.00E+03 1.S3E-06 1.70E-Ol O.OOE+OO 4. 66E-Ol 

4.00E+03 3.S3E-07 1. 72E-Ol O.OOB+OO 4.66E-Ol 

S.OOE+03 1.9lE-07 1. 72E-Ol O.OOE+OO 4. 66E-Ol 

7.00E+03 4. 79E-OS 1. 73E-Ol O.OOE+OO 4. 66E-Ol 

B-199 
CLASS W AMAD - 1 HICllON BAI.J.lLIFE= 3.13E+02 DAYS HANGARESE S4 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l4E-02 2. 76E-Ol 2. 35E-Ol 5. 63E-02 6. 39E-Ol 

2.00E-Ol 7.37E-02 2. 65E-Ol 1.97E-Ol 1.02E-Ol 6. 38E-Ol 

3.00E-Ol 7.70E-02 2.56E-Ol 1. 66E-Ol 1. 38E-Ol 6.37E-Ol 

4.00E-Ol 8.04E-02 2. 47E-Ol 1.39E-Ol 1. 68E-Ol 6. 34E-OI 

5.00E-Ol 8.35E-02 2.39E-OI I.I7E-0l 1.9IE-OI 6.3IE-0l 

6.00E-OI 8. 63E-02 2. 32E-OI 9.85E-02 2.09E-Ol 6. 26E-OI 

7.00E-OI 8. 87E-02 2. 26E-Ol 8. 28E-02 2. 22E-Ol 6.20E-Ol 

8.00E-OI 9.07E-02 2.20E-OI 6. 96E-02 2. 32E-OI 6. 13E-OI 

9.00E-OI 9. 24E-02 2.15E-0l 5. 85E-02 2. 38E-Ol 6.04E-Ol 

1.OOE+OO 9. 38E-02 2.l0E-OI 4. 92E-02 2.40E-Ol 5. 93E-Ol 

2.00E+OO 9.8IE-02 1. 76E-OI 8. 68E-03 1.8lE-Ol 4. 65E-Ol 

3.00E+OO 9.6lE-02 1. 59E-Ol 1. 53E-03 I.OOE-OI 3. 57E-Ol 

4.00E+OO 9. 29E-02 1.49E-Ol 2.70E-04 5.04E-02 2. 93E-Ol 

5.00E+OO 8. 96E-02 1. 43E-Ol 4. 76E-05 2.50E-02 2. 58E-Ol 

6.00E+OO 8. 64E-02 1. 39E-Ol 8.40E-06 1. 29E-02 2.38E-0l 

7.00E+OO 8. 36E-02 1. 36E-Ol 1. 48E-06 7.I5E-03 2.27E-Ol 

8.00E+OO 8.10E-02 1.33E-Ol 2.6lE-07 4. 43E-03 2.l9E-OI 

9.00E+OO 7. 86E-02 1.3IE-Ol 4. 61E-08 . 3.l2E-03 2. 13E-OI 

I.OOE+OI 7. 65E-02 1.29E-Ol O.OOE+OO 2. 48E-03 2.08E-OI 

2.00E+OI 6. 25E-02 1.llE-0l O.OOE+OO I. 62E-03 1.75E-Ol 

3.00E+Ol 5.38E-02 9. 57E-02 O.OOE+OO 1. 38E-03 I.5IE-0l 

4.00E+Ol 4. 68E-02 8. 24E-02 O.OOE+OO 1.17E-03 1. 

5.00E+Ol 4.09E-02 7.09E-02 O.OOE+OO 9. 97E-04 1.1 

6.00E+Ol 3. 57E-02 6.llE-02 O.OOE+OO 8. 49E-04 9.77E-02 

7.00E+Ol 3.I2E-02 5. 26E-02 O.OOE+OO 7.23E-04 8. 45E-02 

8.00E+Ol 2.73E-02 . 4. 52E-02 O.OOE+OO 6. 16E-04 7. 32E-02 

9.00E+Ol 2. 39E-02 3.89E-02 O.OOE+OO 5.24E-04 6.33E-02 

1.00E+02 2.09E-02 3. 35E-02 O.OOE+OO 4. 46E-04 5. 48E-02 

2.00E+02 5. 42E,...03 7.40E-03 O.OOE+OO 8. 94E-05 1.29E-02 

3.00E+02 1. 38E-03 1. 62E-03 O.OOE+OO 1. 79E-05 3.0lE-03 

4.00E+02 3.40E-04 3.52E-04 O.OOE+OO 3. 58E-06 6. 96E-04 

5.00E+02 8.l8E-05 7.6lE-05 O.OOE+OO 7.l8E-07 1. 59E-04 

6.00E+02 1.92E-05 1. 64E-05 O.OOE+OO I.44E-07 3. 57E-05 

7.00E+02 4. 44E-06 3.50E-06 O.OOE+OO 2. 88E-08 7. 97E-06 

8.00E+02 1.OlE-06 7.45E-07 O.OOE+OO O.OOE+OO 1.76E-06 

9.00E+02 2. 27E-07 1. 58E-07 O.OOE+OO O.OOE+OO 3. 85E-07 , .1 1.00E+03 5.04E-08 3.35E-08 O.OOE+OO O.OOE+OO 8. 39E-08 

B-200 
CLASS W AMAD = 1 MICRON BALFLlFE== 3.13E+02 DAYS HARGADSE 54 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 3. 88E-04 8.0lE-06 

2.00E-Ol 8. 47E-04 1.60E-04 

3.00E-OI I. 32E-03 8.04E-04 

4.00E-Ol 1.8lE-03 2. 33E-03 

S.OOE-OI 2. 32E-03 S.04E-03 

6.00E-OI 2. 84E-03 9. llE-03 

7.00E-Ol 3. 38E-03 I. 46E-02 

8.00E-Ol 3. 92E-03 2.ISE-02 

9.00E-OI 4. 48E-03 2. 98E-02 

1.00E+00 S.03E-03 S.03E-03 3. 92E-02 3. 92E-02 

2.00E+00 S.60E-03 1.06E-02 1. 22E-Ol 1.6lE-01 

3.00E+00 S.23E-03 1. S8E-02 1.02E-01 2. 62E-Ol 

4.00E+00 4.7lE-03 2.0SE-02 S.86E-02 3.20E-OI 

S.OOE+OO 4. 22E':"'"03 2. 47E-02 3.00E-02 3.S0E-OI 

6.00E+00 3. 78E-03 2. 84E-02 1. SOE-02 3. 64E-Ol 

7.00E+00 3.40E-03 3. 17E-02 7. 69E-03 3.7lE-01 

8.00E+00 3.07E-03 3.47E-02 4. 23E-'03 3. 74E-Ol 

9.00E+00 2. 79E-03 3.7SE-02 2.60E-03 3. 76E-Ol 

1.00E+Ol 2. SSE-03 3. 99E-02 1.8lE-03 3.77E-Ol 

2.00E+Ol 1. 42E-03 S.68E-02 9. 34E-04 3. 79E-Ol 

3.00E+Ol 1.lOE-03 6. 76E-02 7.9SE-04 3. 79E-Ol 

4.00E+Ol 9. 36E-04 7.6lE-02 6~ 77E-04 3. 78E-Ol 

S.OOE+Ol 8.l4E-04 8.30E-02 S.76E-04 3. 76E-Ol 

6.00E+Ol 7. llE-04 8. 86E-02 4.9lE-04 3. 73E-ol 

7.00E+Ol 6.22E-04 9. 32E-02 4.l8E-04 3. 69E-Ol 

8.00E+Ol S.44E-04 9. 69E-02 3.S6E-04 3.6SE-Ol 

9.00E+Ol 4. 76E-04 9. 98E-02 3.03E-04 3.60E-Ol 

1.00E+02 4.l6E-04 1.02E-01 2.S8E-04 3.SSE-OI 

2.00E+02 1.-68E-04 1.02E-OI S.17E-OS 2. 96E-Ol 

3.00E+02 2. 72E-oS 8.6SE-02 1.03E-OS 2. 39E-OI 

4.00E+02 6. 68E-06 7.06E-02 2.07E-06 1. 92E-Ol 

S.00E+02 1.60E-06 S.68E-02 4.lSE-07 1.S4E-01 

6.00E+02 3.7SE-07 4.'S6E-02 8.3lE-08 1.23E-0l 

7.00E+02 8. 63E-08 3.6SE-02 1. 66E-08 9. 87E-02 

~~ . 8.00E+02 1. 96E-08 2. 93E-02 O.OOE+OO 7.9lE-02 

B-201 
CLASS W AHAD - 1 MICRON STABLE MANGANESE 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTE1UC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l4E-02 2. 76E-Ol 2. 35E-Ol 5.64E-02 6. 39E-Ol 

2.00E-Ol 7. 38E-02 2. 65E-Ol 1. 97E-Ol 1.02E-Ol 6. 38E-Ol 

3.00E-Ol 7.70E-02 2. 56E-Ol 1.66E-0l 1.38E-Ol 6. 37E-Ol 

4.00E-Ol 8.04E-02 2. 47E-Ol 1. 39E-Ol 1. 68E-Ol 6. 35E-Ol 

5.00E-Ol 8. 36E-02 2.40E-0l 1.17E-0l 1.9lE-Ol 6. 32E-Ol 

6.00E-Ol 8. 64E-02 2. 33E-Ol 9. 86E-02 2.09E-Ol 6. 27E-Ol 

7.00E-Ol 8. 88E-02 2. 27E-Ol 8. 29E-02 2. 23E-Ol 6.21E-Ol 

8.00E-Ol 9.09E-02 2.21E-Ol 6.97E-02 2. 32E-Ol 6.l4E-Ol 

9.00E-Ol 9. 26E-02 2.16E-Ol 5. 86E-02 2. 38E-Ol 6.05E-Ol 

1.OOE+OO 9.40E-02 2.11E-Ol 4. 93E-02 2.4lE-Ol 5. 95E-Ol 

2.00E+OO 9. 86E-02 1.77E-Ol 8.72E-03 1. 82E-Ol 4. 67E-Ol 

3.00E+OO 9. 68E-02 1.60E-Ol 1.54E-03 1.OlE-Ol 3. 59E-Ol 

4.00E+OO 9.37E-02 1.50E-Ol 2. 72E-04 . 5.09E-02 2.95E-Ol 

5.00E+OO 9.06E-02 1.45E-Ol 4. 82E-05 2. 53E-02 2.61E-Ol 

6.00E+OO 8. 76E-02 1.41E-0l 8.51E-06 1.3lE-02 2.41E-Ol 

7.00E+OO 8. 49E-02 1. 38E-Ol 1.5lE-06 7. 26E-03 2.30E-Ol 

8.00E+OO 8. 24E-02 1. 36E-Ol 2. 66E-07 4.51E-03 2. 23E-Ol 

9.00E+OO 8.02E-02 1. 34E-Ol 4.70E-08 3.l8E-03 2.l7E-Ol 

1.OOE+Ol 7.82E-02 1.32E-Ol O.OOE+OO 2. 53E-03 2.13E-Ol 

2.00E+Ol 6. 53E-02 1.16E-Ol O.OOE+OO 1. 69E-03 1. 83E-Ol 

3.00E+Ol 5. 75E-02 1.02E-Ol O.OOE+OO 1. 47E-03 1.61E-Ol 

4.00E+Ol 5.12E-02 9.01E-02 O.OOE+OO 1. 28E-03 1.43E-O 

5.00E+Ol 4. 57E-02 7. 93E-02 O.OOE+OO 1.HE-03 1.26E 

6.00E+Ol 4.08E-02 6. 98E-02 O.OOE+OO 9.70E-04 1. 1 2E-O 1 

7.00E+Ol 3. 65E-02 6. 14E-02 O.OOE+OO 8. 44E-04 9.87E-02 

8.00E+Ol 3. 26E-02 5.40E-02 O.OOE+OO 7. 35E-04 8. 74E-02 

9.00E+Ol 2. 92E-02 4.75E-02 O.OOE+OO 6.40E-04 7. 73E-02 

1.OOE+02 2.61E-02 4.l8E-02 O.OOE+OO 5. 57E-04 6. 84E-02 

2.00E+02 8. 45E-03 1.15E-02 O.OOE+OO 1. 39E-04 2.0lE-02 

3.00E+02 2. 68E-03 3.15E-03 O.OOE+OO 3. 48E-05 5. 86E-03 

4.00E+02 8..26E-04 8.55E-04 O.OOE+OO 8.71E-06 1. 69E-03 

5.00E+02 2. 48E-04 2.31E-04 O.OOE+OO 2.l8E-06 4.81E-04 

6.00E+02 7. 28E-05 6.19E-05 O.OOE+OO 5.44E-07 1.35E-04 

7.00E+02 2.lOE-05 1. 65E-05 O.OOE+OO 1. 36E-07 3.77E-05 

8.00E+02 5.96E-06 4.40E-06 O.OOE+OO 3.40E-08 1.04E-05 

9.00E+02 1. 67E-06 1. 16E-06 O.OOE+OO O.OOE+OO 2. 83E-06 

1.OOE+03 4. 63E-07 3.08E-07 O.OOE+OO O.OOE+OO 7.71E-07 

B-202 
C'IASS W AHAD = 1 KICRON STABLE HANGANESB 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-of 3. 88E-04 8.0lE-06 

2.00E-Ol 8. 47E-04 1.60E-04 

3.00E-Ol 1.32E-03 8.04E-04 

4.00E-Ol 1.8lE-03 2. 33E-03 

S.OOE-Ol 2. 32E-03 S.04E-03 

6.00E-Ol 2.8SE-03 9.l3E-03 

7.00E-Ol 3.38E-03 1. 47E-02 

8.00E-Ol 3. 93E-03 2.l6E-02 

9.00E-Ol 4. 48E-03 2. 98E-02 

1.OOE+OO S.OSE-03 S.OSE-03 3. 93E-02 3. 93E-02 

2.00E+OO S.63E-03 1.07E-02 1.23E-Ol 1. 62E-Ol 

3.00E+OO S.27E-03 1.S9E-02 1.02E-Ol 2. 64E-Ol 

4.00E+OO 4. 76E-03 2.07E-02 5. 92E-02 3.23E-Ol 

S.OOE+OO 4. 27E-03 2.50E-02 3.04E-02 3.S4E-Ol 

6.00E+OO 3. 83E-03 2. 88E-02 1.S2E-02 3. 69E-Ol 

7.00E+OO 3.4SE-03 3. 22E-02 7.8lE-03 3. 77E-Ol 

8.00E+OO 3.l3E-03 3.S4E-02 4.3lE-03 3.81E-0l 

9.00E+OO 2.8SE-03 3. 82E-02 2.6SE-03 3.84E-Ol 

1.OOE+Ol 2.6lE-03 4.08E-02 1.8SE-03 3.8SE-Ol 

2.00E+Ol 1. 48E-03 S.94E-02 9. 77E-04 3. 97E-Ol 

3.00E+Ol 1.17E-03 7.23E-02 8.S0E-04 4.06E-Ol 

4.00E+Ol 1.02E-03 8.3lE-02 7.40E-04 4.l3E-01 

S.OOE+Ol 9.l0E-04 9. 27E-02 6. 44E-04 4.20E-Ol 

6.00E+Ol 8.l3E-04 1.OlE-Ol S.6lE-04 4. 26E-Ol 

7.00E+Ol 7. 26E-04 1.09E-Ol 4. 88E-04 4. 32E-Ol 

8.00E+Ol 6. 49E-04 1. 16E-Ol 4. 25E-04 4. 36E-Ol 

9.00E+Ol S.81E-04 1. 22E-Ol 3.70E-04 4.40E-Ol 

1.OOE+02 S.19E-04 1. 27E-Ol 3. 22E-04 4. 43E-Ol 

2.00E+02 1. 68E-04 1.S8E-OI 8.0SE-OS 4.61E-Ol 

3.00E+02 S.30E-OS 1. 68E-Ol 2.0lE.-OS 4.6SE-Ol 

4.00E+02 1. 62E-OS 1.71E-0l S.03E-06 4. 66E-Ol 

S.OOE+02 4.8SE-06 1. 72E-Ol 1. 26E-06 4. 66E-Ol 

(I.OOE+02 1. 42E-06 1.73E-0l 3.l4E-07 4. 66E-Ol 

7.00E+02 4.08E-07 1. 73E-Ol 7. 86E-08 4. 66E-.Ol , .. 8.00E+02 1.lSE-07 1.73E-Ol 1. 97E-08 4. 66E-Ol 

9.00E+02 3. 23E-08 1. 73E-Ol O.OOE+OO 4. 66E-Ol 

B-203 
GlASS W AMAD - 1 HICR.ON HALFLIPE- 9.86E+02 DAYS IRON 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l8E-02 2. 76E-Ol 2.35E-Ol 5. 64E-02 6. 39E-Ol 

2.00E-Ol 7. 46E-02 2. 65E-Ol 1.97E-Ol 1.02E-Ol 6. 39E-Ol 

3.00E-Ol 7. 83E-02 2. 56E-Ol 1.66E-Ol 1.38E-Ol 6. 38E-Ol 

4.00E-Ol 8. 22E-02 2.47E-Ol 1. 39E-Ol 1. 68E-Ol 6.37E-Ol 

5.00E-Ol 8"59E-02 2.40E-Ol 1.17E-0l 1.9lE-0l 6.34E-Ol 

6.00E-Ol 8. 92E-02 2. 33E-Ol 9. 86E-02 2.09E-Ol 6.30E-Ol 

7.00E-Ol 9.2lE-02 2. 26E-Ol 8.29E-02 2. 23E-Ol 6.24E-Ol 

8.00E-Ol 9.47E-02 2.2lE-Ol 6. 97E-02 2. 32E-Ol 6.l7E-Ol 

9.00E-Ol 9.70E-02 2.l5E-0l 5.86E-02 2.38E-0l 6.09E-Ol 

1.OOE+OO 9. 89E-02 2.llE-Ol 4. 93E-02 2.4lE-Ol 5. 99E-Ol 

2.00E+OO 1.09E-Ol 1.77E-Ol 8.7lE-03 1.82E-Ol 4. 77E-Ol 

3.00E+OO 1. 12E-01 1.60E-Ol 1. 54E-03 1.OlE-Ol 3. 74E-01 

4.00E+OO 1.14E-Ol 1.SOE-Ol 2.72E-04 S.07E-02 3.1SE-0l 

S.OOE+OO 1. 15E-01 1.44E-Ol 4.80E-05 2.52E-02 2. 84E-Ol 

6.00E+OO 1. 16E-Ol 1.40E-01 8. 48E'-06 1.30E-02 2. 69E-01 

7.00E+OO 1.l6E-Ol 1.37E-Ol 1.50E-06 7.22E-03 2. 61E-Ol 

8.00E+OO 1.l7E-Ol 1.35E-01 2. 65E-07 4. 48E-03 2. 56E-01 

9.00E+OO 1.l7E-Ol 1.33E-Ol 4.67E-08 3. 16E-03 2. 54E-Ol 

1.00E+01 1.l8E-0l 1.3lE-Ol O.OOE+OO 2.51E-03 2. 52E-Ol 

2.00E+01 t.22E-Ol 1.lSE-Ol O.OOE+OO 1.67E-03 2. 38E-Ol 

3.00E+01 1. 26E-Ol 1.00E-Ol O.OOE+OO . 1. 44E-03 2.27E-0l 

4.00E+Ol 1. 29E-Ol 8. 76E-02 O.OOE+OO 1.24E-03 2. 18E-01 

5.00E+01 1. 32E-01 7.65E-02 O.OOE+OO 1.08E-03 2.09E-Ol 

6.00E+Ol 1.34E-Ol 6. 69E-02 O.OOE+OO 9.30E-04 2.0lE-Ol 

7.00E+01 1.3SE-Ol S.84E-02 O.OOE+OO 8.04E-04 1.95E-Ol 

8.00E+Ol 1.37E-Ol 5.lOE-02 O.OOE+OO 6.9SE-04 1. 89E-Ol 

9.00E+Ol 1.38E-Ol 4.46E-02 O.OOE+OO 6.0lE-04 1.83E-Ol 

1.OOE+02 1.39E-Ol 3.90E-02 O.OOE+OO 5.l9E-04 1. 78E-Ol 

2.00E+02 1.36E-Ol 1.OOE-02 O.OOE+OO 1. 21E-04 1.46E-Ol 

3.00E+02 1.26E-Ol 2.SSE-03 O.OOE+OO 2. 82E-OS 1. 29E-Ol 

4.00E+02 1.14E-Ol 6. 46E-04 OoOOE+OO 6. 57E-06 1.lSE-Ol 

5.00E+02 1.03E-Ol 1. 62E-04 O.OOE+OO 1.S3E-06 1.03E-Ol 

6.00E+02 9.29E-02 4.06E-OS O.OOE+OO 3. S7E-07 9.30E-02 

7.00E+02 8. 37E-02 1.OlE-OS O.OOE+OO 8.31E-08 8.37E-02 

8.00E+02 7.54E-02 2.50E-06 O.OOE+OO 1.94E-08 7.S4E-02 

9.00E+02 6. 78E-02 6. 18E-07 O.OOE+OO O.OOE+OO 6. 78E-02 

1.OOE+03 6.11E-02 1.S2E-07 O.OOE+OO O.OOE+OO 6.l1E-02 

2.00E+03 2.l4E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.l4E-02 

4.00E+03 2. 62E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.62E-03 

S.OOE+03 9.l7E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.17E-04 

7.00E+03 1.12E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.12E-04 

8.00E+03 3. 93E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3. 93E-OS 

9.00E+03 1. 38E-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.38E-OS 

1.00E+04 4.8lE-06 O.OOE+OO O.OOE+OO O.OOE+OO 4.8lE-06 

B-204 
CLASS W AMAD = 1 MICRON BALFLlFE= 9.86&+02 DAYS IRON 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 11E-06 8.01E-06 

2.00E-01 4. 65E-06 1.60E-04 

3.00E-01 7. 29E-06 8.04E-04 

4.00E-01 1.01E-05 2. 33E-03 

5.00E-01 1.30E-05 5.04E-03 

6.00E-01 1.60E-05 9. 12E-03 

7.00E-01 1. 92E-05 1. 46E-02 

8.00E-01 2. 24E-05 2. 16E-:,02 

9.00E-01 2. 57E-05 2. 98E-02 

1.00E+00 2.91E-05 2. 91E .... 05 3. 92E-02 3. 92E-02 

2.00E+00 3. 64E-05 6. 55E-05 1. 22E-01 1.62E-01 

3.00E+00 3. 84E-05 1.04E-04 1.02E-Ol 2. 64E-01 

4.00E+00 3. 92E-05 1. 43E-04 5.90E-02 3. 22E-01 

5.ooE+00 3. 97E-05 1. 83E-04 3.03E-02 3. 52E-01 

6.00E+00 3. 99E-05 2. 22E-04 1. 51E-02 3. 67E-Ol 

7.00E+00 4.02E-05 2. 62E-04 7.77E-03 3. 75E-01 

8.00E+00 4.04E-05 3.03E-04 4. 29E-03 3.79E-01 

9.00E+00 4.06E-05 3. 43E-04 2. 63E-03 3.81E-01 

1.00E+Ol 4.07E-05 3. 83E-04 1. 84E-03 3. 83E-Ol 

2.00E+01 4. 22E-05 7. 95E-04 9. 63E-04 3. 91E-01 

3.00E+Ol 4. 35E-05 1.22E-03 8.32E-04 3. 97E-01 

4.00E+Ol 4. 46E-05 1.65E-03 7. 19E-04 4.02E-01 

5.00E+01 4.55E-05 2.09E-03 6. 22E-04 4.06E-01 

6.00E+01 4. 63E-05 2. 53E-03 5. 37E-04 4.09E-01 

7.00E+01 4. 69E-05 2. 98E-03 4. 65E-04 4. 11E-01 

8.00E+01 4. 74E-05 3. 43E-03 4.02E-04 4. 12E-Ol 

9.00E+Ol 4.77E-05 3. 88E-03 3. 47E-04 4. 13E-01 

1.00E+02 4.80E-05 4. 33E-03 3.00E-04 4. 13E-Ol 

2.00E+02 4.72E-05 8. 67E-03 6. 99E-05 4.00E-01 

3.00E+02 4. 36E·-05 1. 25E-02 1. 63E-05 3.77E-01 

4.00E+02 3. 96E-05 1.56E-02 3.80E-06 3. 52E-01 

5.00E+02 3. 57E-05 1. 82E-02 8.85E-07 3.28E-01 

6.00E+02 3. 22E-05 2.03E-02 2.06E-07 3.06E-01 

7.00E+02 2.9QE-05 2. 18E-02 4.80E-08 2. 85E-Ol 

8.00E+02 2. 61E-05 2.30E-02 1. 12E-08 2. 66E-01 

9.00E+02 2. 35E-05 2. 38E-02 O.OOE+OO 2. 48E-01 

1.00E+03 2. 12E-05 2. 44E-02 O.OOE+OO 2. 31E-Ol 

2.00E+03 7.41E-06 2.09E-02 O.OOE+OO 1. 14E-01 

4.00E+03 9.08E-07 7. 74E-03 O.OOE+OO 2.80E-02 

5.00E+03 3. 18E-07 4. 21E-03 O.OOE+OO 1. 39E-02 

7.00E+03 3. 89E-08 1. 14E-03 O.OOE+OO 3. 39E-03 

B-205 
CLASS W AHA» = 1 HICltON HALFLIFE= 4.45E+Ol DAYS IRON 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l7E-02 2. 76E-Ol 2. 34E-Ol 5.63E-02 6. 38E-Ol 

2.00E-Ol 7. 44E-02 2. 64E-Ol 1.97E-Ol 1.OlE-Ol 6.37E-Ol 

3.00E-Ol 7.80E-02 2.55E-Ol 1. 65E-Ol 1. 38E-Ol 6. 35E-Ol 

4.00E-Ol 8.l7E-02 2. 46E-Ol 1. 39E-Ol 1.67E-Ol 6. 33E-OI 

S.OOE-Ol 8.S2E-02 4.38E-Ol 1.16E-OI 1.90E-0l 6. 29E-Ol 

6.00E-Ol 8. 84E-02 2.3lE-OI 9. 17E-02 2.07E-OI 6.24E-Ol 

7.00E-OI 9.12E-02 2. 24E-OI 8.20E-02 2.20E-Ol 6.l8E-Ol 

8.00E-Ol 9. 36E-02 2.l8E-OI 6.89E-02 2. 29E-OI 6.l0E-Ol 

9.00E-Ol 9.S7E-02 2.13E-Ol 5. 78E-02 2.3SE-Ol 6.0lE-OI 

I.OOE+OO 9.7SE-02 2.07E-Ol 4. 86E-02 2. 37E-Ol 5.9lE-OI 

2.00E+OO 1.06E-Ol 1.72E-Ol 8.4SE-03 1.76E-Ol 4. 63E-Ol 

3.00E+OO 1.07E-OI 1.S3E-OI 1. 47E-03 9. 63E-02 3.S8E-Ol 

4.00E+OO I.07E-Ol 1.4lE-Ol 2.S6E-04 4. 78E-02 2.97E-Ol 

S.OOE+OO I.07E-OI 1. 34E-Ol 4. 46E-OS 2. 34E-02 2. 64E-Ol 

6.00E+OO 1.06E-Ol 1.28E-OI 7.7SE-06 1.19E-02 2.46E-Ol 

7.00E+OO 1.OSE-Ol 1. 24E-OI 1.3SE-06 6.5lE-03 2. 35E-OI 

8.00E+OO 1.04E-0l 1.20E-OI 2.3SE-07 3. 98E-03 2. 28E-OI 

9.00E+OO I.03E-Ol 1.16E-Ol 4.09E-08 2.17E-03 2. 22E-Ol 

1.OOE+OI 1.02E-Ol 1.13E-Ol O.OOE+OO 2.l7E-03 2.l7E-Ol 

2.00E+Ol 9.07E-02 8.5lE-02 O.OOE+OO 1. 24E-03 1. 17E-Ol 

3.00E+OI 8.06E-02 6.4lE-02 O.OOE+OO 9.22E-04 1.46E-Ol 

4.00E+Ol 7.IIE-02 4. 83E-02 O.OOE+OO 6. 87E-04 1.20E-Ol 

5.00E+Ol 6. 26E-02 3. 64E-02 O.OOE+OO S.12E-04 9.9SE-02 

6.00E+Ol S.48E-02 2. 74E-02 O.OOE+OO 3.SlE-04 8.26E-02 

7.00E+OI 4. 79E-02 2.06E-02 O.OOE+OO 2. 84E-04 6. 88E-02 

8.00E+OI 4.l7E-02 1. SSE-02 O.OOE+OO 2.l2E-04 S.74E-02 

9.00E+OI 3. 62E-02 1.17E-02 O.OOE+OO 1. SSE-04 4.80E-02 

1.OOE+02 3.14E-02 8.8lE-03 O.OOE+OO 1.17E-04 4.03E-02 

2.00E+02 6. 97E-03 S.12E-04 O.OOE+OO 6.19E-06 7. 49E-03 

3.00E+02 1. 46E-03 2.9SE-OS O.OOE+OO 3. 26E-07 1.49E-03 

4.00E+02 2. 99E-04 1. 69E-06 O.OOE+OO 1.72E-08 3.0IE-04 

S.OOE+02 6. lIE-OS 9.62E-08 O.OOE+OO O.OOE+OO 6.l2E-OS 

6.00E+02 1.2SE-OS O.OOE+OO O.OOE+QO O.OOE+OO 1.2SE-OS 

7.00E+02 2.S4E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.S4E-06 

8.00E+02 S.17E-07 O.OOE+OO O.OOE+OO O.OOE+OO S.17E-07 

9.00E+02 1.OSE-07 O.OOE+OO O.OOE+OO O.OOE+OO I.OSE-07 

1.OOE+03 2.14E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.14E-OS 

B-206 
CLASS W AHAD - 1 MICRON BALl'LIFE- 4.45£+01 DAYS nOB 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.11E-06 8.00E-06 

2.00E-Ol 4. 63E-06 1.60E-04 

3.00E-Ol 7.26E-06 8.00E-04 

4.00E-Ol 1.OOE-05 2.3lE-03 

5.00E-Ol 1. 29E-05 5.00E-03 

6.00E-Ol 1. 59E-05 9.04E-03 

7.00E-Ol 1.90E-05 1. 45E-02 

8.00E-Ol 2.2lE-05 2. 13E-02 

9.00E-Ol 2. 54E-05 2. 94E-02 

1.OOE+OO 2. 87E-05 2. 87E-05 3. 87E-02 3. 87E-02 

2.00E+OO 3. 53E-05 6. 35E-05 1.19E-0l 1.57E-Ol 

3.00E+OO 3. 68E-05 9. 93E-05 9. 76E-02 2. 52E-Ol 

4.00E+OO 3.70E-05 1. 35E-04 5.56E-02 3.04E-Ol 

5.00E+OO 3. 68E-05 1. 69E-04 2.8lE-02 3. 27E-Ol 

6.00E+OO 3. 65E-05 2.03E-04 1.38E-02 3. 36E-Ol 

7.00E+OO 3. 62E-05 2. 36E-04 7.00E-03 3. 38E-Ol 

8.00E+OO 3. 58E-05 2. 69E-04 3.80E-03 3. 36E-Ol 

9.00E+OO 3. 55E-05 3.00E-04 2.30E-03 3. 33E-Ol 

1.OOE+Ol 3.5lE-05 3.30E-04 1.58E-03 3.30E-Ol 

2.00E+O] 3.l4E-05 5.9lE-04 7.l5E-04 2.90E-Ol 

3.00E+Ol 2.79E-05 7.80E-04 5. 33E-04 2.54E-Ol 

4.00E+Ol 2. 46E-05 9.lOE-04 3. 97E-04 2. 22E-Ol 

5.00E+Ol 2. 17E-05 9. 93E-04 2. 96E-04 1. 93E-Ol 

6.00E+Ol 1.90E-05 1.04E-03 2.20E-04 1. 68E-Ol 

7.00E+Ol 1. 66E-05 1.05E-03 1.64E-04 1. 45E-Ol 

8.00E+Ol 1. 44E-05 1.04E-03 1. 22E-04 1. 26E-Ol 

9.00E+Ol 1. 25E-05 1.02E-03 9.llE-05 1.OBE-Ol 

1.OOE+02 1.09E-05 9. 79E-04 6. 79E-05 9. 35E-02 

2.00E+02 2. 42E-06 4.44E-04 3.5BE-06 2.05E-02 

3.00E+02 5.05E-07 1. 44E-04 1. B9E-07 4. 36E-03 

4.00E+02 1.04E-07 4.l0E-05 O.OOE+OO 9.2lE-04 

5.00E+02 2.l2E-OB 1.OBE-05 O.OOE+OO 1. 94E-04 

B-207 
ClASS W AHAD = 1 HICltOR BALPLIFE= 7.08E+Ol DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.71E-02 2.76E-Ol 2. 34E-Ol 5.67E-02 6.34E-0l 

2.00E-Ol 6.4lE-02 2. 65E-Ol 1.97E-Ol 1.03E-01 6. 29E-Ol 

3.00E-Ol 6.l9E':"02 2.55E-Ol 1. 65E-0l 1.42E-01 6.24E-Ol 

4.00E-Ol 6.02E-02 2. 46E-Ol 1. 39E-Ol 1. 73E-Ol 6.lBE-01 

5.00E-Ol 5.B6E-02 2.3BE-Ol 1.17E-Ol 1.9BE-01 6.l1E-0l 

6.00E-Ol 5. 73E-02 2.3lE-01 9.BlE-02 2.17E-Ol 6.04E-Ol 

7.00E-Ol 5. 59E-02 2.25E-Ol B.24E-02 2.3lE-Ol 5.9SE-Ol 

B.OOE-Ol 5. 47E-02 2.l9E-Ol 6. 92E-02 2.4lE-01 S.B4E-Ol 

9.00E-Ol 5. 34E-02 2.l4E-0l 5.BIE-02 2.4BE-Ol 5.73E-Ol 

1.00E+OO S.23E-02 2.09E-Ol 4.BBE-02 2. 51E-Ol S.60E-Ol 

2.00E+00 4. 36E-02 l.74E-Ol B.SSE-03 1. B9E-0l 4. 15E-Ol 

3.00E+OO 3.B9E-02 1.5SE-01 I.S0E-03 1.04E-Ol 3.00E-Ol 

4.00E+OO 3.S9E-02 1. 44E-Ol 2.62E-04 5.20E-02 2. 33E-Ol 

5.00E+OO 3. 36E-02 1.3BE-01 4.S9E-OS 2.S6E-02 1.97E-Ol 

6.~+06 3.l7E-02 1. 33E-Ol B.03E-06 1.31E-02 1.7BE-Ol 

7. +00 3.00E-02 1. 29E-Ol 1.4lE-06 7. 19E-03 1. 66E-Ol 

B.OOE+OO 2. BSE-02 1.26E-Ol 2.46E-07 4.41E-03 1. 59E-Ol 

9.00E+OO 2.71E-02 1.23E-Ol 4.3lE-OB 3.0BE-03 1.S3E-OI 

1.00E+Ol 2.S9E-02 1.20E-Ol O.OOE+OO 2.42E-03 1.4BE-Ol 

2.00E+Ol 1. BSE-02 9.S5E-02 O.OOE+OO 1. 46E-03 1.16E-01 

3.00E+Ol 1. 53E-02 7. 63E-02 O.OOE+OO 1. 16E-03 9. 27E-02 

4.00E+Ol 1. 33E-02 6.09E-02 O.OOE+OO 9. 12E-04 7. 51E-02 

S.OOE+Ol 1. 17E-02 4.B6E-02 O.OOE+OO 7.20E-04 6.10E-02 

6.00E+Ol 1.04E-02 3.BBE-02 O.OOE+OO 5.6BE-04 4.9BE-02 

7.00E+Ol 9.30E-03 3.09E-02 O.OOE+OO 4. 49E-04 4.07E-02 

B.OOE+Ol B.29E-03 2. 47E-02 O.OOE+OO 3. 54E-04 3. 33E-02 

9.00E+Ol 7.3BE-03 1.97E-02 O.OOE+OO 2. BOE-04 2. 73E-02 

1.00E+02 6.S7E-03 1. 57E-02 O.OOE+OO 2. 21E-04 2.2SE-02 

2.00E+02 2.0SE-03 1. 63E-03 O.OOE+OO 2.07E-05 3.70E-03 

3.00E+02 6.60E-04 1. 67E-04 O.OOE+OO 1. 95E-06 B.29E-04 

4.00E+02 2. 19E-04 1.70E-OS O.OOE+OO 1. B3E-07 2. 37E-04 

5.00E+02 7. 43E-05 1. 73E-06 O.OOE+OO 1. 72E-OB 7.60E-05 

6.00E+02 2.S4E-05 1. 74E-07 O.OOE+OO O.OOE+OO 2. S6E-05 

7.00E+02 B.73E-06 1.7SE-OB O.OOE+OO O.OOE+OO B.7SE-06 

B.00E+02 3.00E-06 O.OOE+OO O.OOE+OO O.OOE+OO 3.00E-06 

9.00E+02 1.03E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-06 

1.OOE+03 3. 56E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3. 56E-07 

B-20B 
CLASS W AHAD = 1 KICRON JIALllLIFE= 7.088+01 DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24 .... HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 3.3SE-03 S.4 E-04 

2.00E-OI 6.S6E-03 I.S3E-03 

3.00E-OI 1.00E-02 3.05E-03 

4.00E-OI I. 29E-02 4.SIE-03 

S.00E-01 1.S5E-02 7.3 E-03 

6.00E-01 1.S0E-02 1.07E-02 

7.00E-01 2.01E-02 1.S0E-02 

S.00E-01 2. 22E-02 2.03E-02 

9.00E-01 2.40E-02 2. 64E-02 

1.00E+00 2. 56E-02 2.SSE-02 3. 33E-02 3. 33E-02 

2.00E+OO 1.0SE-02 3. 63E-02 S.73E-02 1.20E-OI 

3.00E+00 4. 99E-03 4.09E-02 7. 13E-02 1.90E-01 

4.00E+00 2. 94E-03 4. 34E-02 4.lOE-02 2. 29E-01 

S.OOE+OO 2.16E-03 4.S2E-02 2.lOE,..02 2.4SE-01 

6.00E+00 1. 79E-03 4.6SE-02 1.06E-02 2.S6E-01 

7.00E+00 1.S6E-03 4.7SE-02 S.SSE-03 2.S9E-01 

S.OOE+OO 1.40E-03 4.S6E-02 3.17E-03 2.60E-OI 

9.00E+00 1. 27E-03 4.-94E-02 2.03E-03 2.S9E-01 

1.00E+OJ 1.lSE-03 S.0IE-02 1.47E-03 2. S9E-01 

2.00E+Ol S.47E-04 S.26E-02 7.00E-04 2. 43E-Ol 

3.00E+Ol 3. 37E-04 S.17E-02 S.30E-04 2. 26E-Ol 

4.00E+Ol 2. 46E-04 4. 96E-02 4. 13E-04 2.09E-OI 

S.OOE+OI 1. 94E-04 4.70E-02 3.26E-04 1.93E-Ol 

6.00E+Ol I.SSE-04 4. 42E-02 2.S9E-04 1.70E-Ol 

7.00E+Ol 1.29E-04 4.1SE-02 2.0SE-04 1. 63E-Ol 

S.OOE+Ol 1.06E-04 3.S7E-02 1. 63E-D4 1.SOE-01 

9.00E+Ol S.77E-OS 3.60E-02 1.30E-04 1. 37E-0l 

1.00E+02 7. 23E-OS 3.3SE-02 1.03E-04 1.2SE-01 

2.00E+02 1.04E-OS 1. 43E-02 1.06E-OS 4. 93E-02 

3.00E+02 1.60E-06 S.62E-03 1.1SE-06 1.S7E-02 

4.00E+02 2. 93E-07 2. 16E-03 1. 43E-07 7.1 E-03 

S.00E+02 6 .• SSE-OS S.lSE-04 2. 37E-OS 2.66E-03 

6.00E+02 1. 97E-OS 3.10E-04 O.OOE+OO 1.00E-03 

B-209 
· CLASS V AMAD = 1 HICRON STABLE COBALT 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 72E-02 2. 76E-Ol 2.3SE-Ol S.6SE-02 6.3SE-Ol 

2.00E-Ol 6.42E-02 2.6SE-Ol 1. 97E-Ol 1.04E-Ol 6.30E-Ol 

3.00E-Ol 6.2lE-02 2.S6E-Ol 1. 66E-Ol 1.42E-Ol 6. 26E-Ol 

4.00E-Ol 6.04E-02 2. 47E-Ol 1.39E-Ol 1. 73E-Ol 6.2lE-Ol 

S.OOE-Ol S.S9E-02 2.40E-Ol 1.17E-Ol 1.99E-Ol 6.l4E-Ol 

6.00E-Ol S.76E-02 2. 33E-Ol 9.S6E-02 2.lSE-Ol 6.07E-Ol 

7.00E-Ol S.63E-02 2.27E-Ol S.29E-02 2. 33E-Ol 5. 99E-Ol 

S.OOE-Ol 5.5lE-02 2.2lE-Ol 6. 97E-02 2. 43E-ol S.S9E-Ol 

9.00E-Ol 5.39E-02 2.l6E-Ol S.S6E-02 2. SOE-Ol 5.7SE-Ol 

1.OOE+OO 5.2SE-02 2.11E-Ol 4. 93E-02 2. 53E-Ol 5. 66E-Ol 

2.00E+OO 4. 44E-02 1.77E-OI S.72E-03 1.93E-OI 4. 23E-Ol 

3.00E+OO 4.00E-02 1.60E-Ol 1.54E-03 1.07E-Ol 3.0SE-Ol 

4.00E+OO 3.73E-02 1.50E-Ol 2. 72E-04 5.40E-02 2. 42E-Ol 

5.00E+OO 3. 53E-02 1.4SE-OI 4.S2E-05 2. 69E-02 2.07E-Ol 

6.00E+OO 3. 36E-02 1.41E-Ol S.SlE-06 1.39E-02 1.SSE-0l 

7.00E+OO 3.21E-02 1.3SE-Ol 1.51E-06 7.70E-03 1.7SE-Ol 

S.OOE+OO 3.0SE-02 1. 36E-0l 2.66E-07 4.77E-03 1.71E-OI 

9.00E+OO 2. 96E-02 1. 34E-Ol 4.70E-OS 3. 36E-03 1. 67E-Ol 

1.OOE+Ol 2.S6E-02 1.32E-OI O.OOE+OO 2. 67E-03 1.63E-OI 

2.00E+Ol 2. 26E-02 1.16E-Ol O.OOE+OO 1.7SE-03 1.4lE-OI 

3.00E+Ol 2.0SE-02 1.02E-Ol O.OOE+OO 1. SSE-03 1. 24E-Ol 

4.00E+Ol 1. 96E-02 9.0lE-02 O.OOE+OO 1.3SE-03 1.l1E-OI 

S.OOE+Ol 1. 92E-02 7. 93E-02 O.OOE+OO ·1.l7E-03 9. 96E-02 

6.00E+Ol 1.SSE-02 6.9SE-02 O.OOE+OO 1.02E-03 S.96E-02 

7.00E+Ol 1. SSE-02 6. 14E-02 O.OOE+OO S.90E-04 S.07E-02 

S.OOE+Ol I.SIE-02 5.40E-02 O.OOE+OO 7.7SE-04 7. 29E-02 

9.00E+Ol 1. 78E-02 4.7SE-02 O.OOE+OO 6.7SE-04 6.60E-02 

1.00E+02 1.7SE-02 4.1SE-02 O.OOE+OO S.S7E-04 S.99E-02 

2.00E+02 1.4SE-02 1.lSE-02 O.OOE+OO 1. 47E-04 2.62E-02 

3.00E+02 1.2SE-02 3.1SE-03 O.OOE+OO 3. 67E-OS 1. 56E-02 

4.00E+02 1 .• ~lOE-02 S.SSE-04 O.OOE+OO 9.1SE-06 1. 19E-02 

5.00E+02 9. 93E-03 2. 31E-04 O.OOE+OO 2.29E-06 1.02E-02 

6.00E+02 9.04E-03 6.l9E-OS O.OOE+OO S.74E-07 9.10E-03 

7.00E+02 S.27E-03 1.6SE-OS O.OOE+OO 1. 43E-07 S.2SE-03 

S.OOE+02 7. S7E-03 4.40E-06 O.OOE+OO 3.5SE-OS 7.SSE-03 

9.00E+02 6. 94E-03 1.16E-06 O.OOE+OO O.OOE+OO 6. 94E-03 

1.00E+03 6. 36E-03 3.0SE-07 O.OOE+OO O.OOE+OO 6. 36E-03 

2.00E+03 2.6SE-03 O.OOE+OO O.OOE+OO O.OQE+OO 2.6SE-03 

4.00E+03 4. 73E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 73E-04 

S.OOE+03 1. 99E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 99E-04 

6.00E+03 S.37E-OS O.OOE+OO O.OOE+OO O.OOE+OO S.37E-05 

7.00E+03 3.S2E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.S2E-OS 

S.OOE+03 1.4SE-OS O.OOE+OO O.OOE+OO O.OOE+OO 1.4SE-OS 

9.00E+03 6. 22E-06 O.OOE+OO O .. OOE+OO O.OOE+OO 6.22E-06 

1.00E+04 2.62E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 62E-06 

B-2l0 
CLASS W AHAD .. 1 HICIlON STABLE COBALT S9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.35E-03 S.47E-04 

2.00E-Ol 6.SSE-03 1.S3E-03 

3.00E-Ol 1.OlE-03 3.06E-03 

4.00E-Ol 1. 29E-02 4.S3E-03 

5.00E-Ol 1.57E-02 7. 33E-03 

6.00E-Ol 1.SlE-02 1.07E-02 

7.00E-Ol 2.02E-02 1.5lE-02 

S.OOE-Ol 2. 23E-02 2.05E-02 

9.00E-Ol 2. 42E-02 2. 67E-02 

1.OOE+OO 2. 59E-02 2. 59E-02 3. 37E-02 3.37E-02 

2.00E+OO 1.lOE-02 3. 69E-02 S.S7E-02 1. 23E-Ol 

3.00E+OO S.14E-03 4.2lE-02 7. 33E-Ol 1. 96E-Ol 

4.00E+OO 3.0SE-03 4.S1E-02 4. 27E-02 2. 39E-Ol 

S.OOE+OO 2. 26E-03 4. 73E-02 2.2lE-02 2.61E-Ol 

6.00E+OO 1.90E-03 4. 93E-02 1.12E-02 2.12E-Ol 

7.00E+OO 1.6SE-03 S.lOE-02 S.9SE-03 2.7SE-Ol 

S.OOE+OO 1.S2E-03 5. 25E-02 3. 43E-03 2.SlE-Ol 

9.00E+OO 1.3BE-03 S.3SE-02 2. 22E-03 2.B3E-Ol 

1.OOE+Ol 1.2BE-03 S.52E-02 1.63E-03 2. BSE-Ol 

2.00E+Ol 6. 66E-04 6.40E-02 S.S3E-Ol 2.9SE-Ol 

3.00E+Ol 4.S3E-04 6. 94E-02 7.13E-0l 3.03E-Ol 

4.00E+Ol 3.6SE-04 7. 33E-02 6.llE-04 3.09E-Ol 

S.OOE+Ol 3.17E-04 7. 67E-02 S.33E-04 3.lSE-Ol 

6.00E+Ol 2.S3E-04 7. 97E-02 4.6SE-04 3.20E-Ol 

7.00E+0l 2.S7E-04 S.23E-02 4.07E-04 3. 24E-Ol 

S.OOE+Ol 2. 33E-04 S.4SE-02 3.S7E-04 3.2BE-Ol 

9.00E+Ol 2.llE-04 B.70E-02 3.13E-04 3.3lE-Ol 

1.OOE+02 1. 92E-04 B.90E-02 2.7SE-04 3. 34E-Ol 

2.00E+02 7.37E-OS 1.OlE-Ol 7.53E-05 3. 49E-Ol 

3.00E+02 3. OlE-OS 1.06E-Ol 2.l7E-OS 3.S4E-Ol 

4.00E+02 1. 46E-05 1.OBE-Ol 7.20E-06 3.SSE-Ol 

5.00E+02 9.1SE-06 1.09E-Ol 3.l7E-06 3.S5E-Ol 

6.00E+02 6. 99E-06 1.lOE-Ol 1.97E-06 3.56E-Ol 

7.00E+02 5.9SE-06 1.llE-Ol 1.SSE-06 3.S6E-Ol 

S.OOE+02 5.33E-06 1.UE-Ol 1.3SE-06 3. S6E-Ol 

9.00E+02 4.S3E-06 1.12E-Ol 1.2lE-06 3.S6E-Ol 

1.OOE+03 4. 42E-06 1.12E-Ol 1.11E-06 3.S6E-Ol 

2.00E+03 1. BSE-06 1.l5E-Ol 4. 64E-07 3.S7E-Ol 

3.00E+03 7.SlE-07 1. 11E-Ol 1.9SE-07 3. S7E-Ol 

4.00E+03 3.2BE-07 1.17E-Ol S.20E-OS 3. 57E-Ol 

5.00E+03 1.3BE-07 1.lSE-Ol 3.45E-OS 3.S7E-Ol 

6.00E+03 S.79E-OB 1.lBE-Ol 1.4SE-OB .3.S7E-Ol 

7.00E+03 2. 43E-OB 1.lBE-Ol O.OOE+OO 3.S7E-Ol 

B-211 
CLASS V .AHAD = 1 MICRON IlALPLlPE- 1.92E+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 6.72E-02 2.76E-Ol 2.3SE-Ol S.6BE-02 6.3SE-Ol 

2.00E-01 6. 42E-02 2.6SE-01 1.97E-01 1.04E-01 6.30E-01 

3.00E-01 6. 21E-02 2. S6E-01 1.66E-01 1.42E-01 6. 26E-01 

4.00E-01 6.04E-02 2. 47E-01 1. 39E-01 1. 73E-01 6.20E-01 

S.OOE-01 S.B9E-02 2.40E-01 1.17E-0l 1.99E-01 6. 14E-01 

6.00E-01 S.76E-02 2. 33E-01 9.B6E-02 2.1BE-01 6.07E-Ol 

7.00E-Ol S.63E-02 2.26E-Ol B.29E-02 2. 33E-Ol S.99E-Ol 

B.OOE-Ol S.SlE-02 2.2IE-Ol 6. 97E-02 2. 43E-Ol S.B9E-01 

9.00E-Ol S.39E-02 2.l6E-0l S.B6E-02 2. SOE-Ol S.7BE-Ol 

1.00E+OO S.2BE-02 2.11E-Ol 4. 93E-02 2.S3E-01 5. 66E-Ol 

2.00E+OO 4. 44E-02 1.77E-Ol B.7lE-03 1. 93E-01 4. 23E:"'Ol 

3.00E+OO 4.00E-02 1.60E-01 1.S4E-03 1.07E-01 3.0BE-Ol 

4.00E+OO 3. 73E-02 1. SOE-01 2. 72E-04 S.40E-02 2. 42E-Ol 

S.OOE+OO 3.S2E-02 1. 44E-Ol 4.B1E-OS 2.6BE-02 2.06E-01 

6.00E+OO 3.3SE-02 1.41E-0l B.SOE-06 1.3BE-02 1.BBE-01 

7.00E+OO 3.20E-02 1.3BE-Ol 1.S0E-06 7.6BE-03 1.77E-Ol 

B.OOE+OO 3.07E-02 1.3SE-Ol 2.6SE-07 4. 76E-03 1.71E-Ol 

9.00E+OO 2.9SE-02 1. 33E-Ol 4. 69E-OB 3.3SE-03 1. 66E-01 

1.00E+Ol 2.B4E-02 1.32E-Ol O.OOE+OO 2.66E-03 1.63E-Ol 

2.00E+01 2. 24E-02 1.lSE-Ol O.OOE+OO 1.77E-03 1.40E-Ol 

3.00E+Ol 2.03E-02 1.OlE-Ol O.OOE+OO 1.S3E-03 1. 23E-01 

4.00E+Ol 1. 94E-02 B.BBE-02 O.OOE+OO 1. 33E-03 1.09E-O 

S.OOE+Ol 1. BBE-02 7. 78E-02 O.OOE+OO 1.lSE-03 9.7 

6.00E+Ol 1. 84E-02 6.B3E-02 O.OOE+OO 1.OOE-03 8.77E-02 

7.00E+Ol 1.80E-02 S.9BE-02 O.OOE+OO B.6BE-04 7.87E-02 

8.00E+Ol 1. 76E-02 S.2SE-02 O.OOE+OO 7.S3E-04 7.0BE-02 

9.00E+01 1.72E-02 4.60E-02 O.OOE+OO 6. SJE-04 6. 39E-02 

1.OOE+02 1.69E-02 4.03E-02 O.OOE+OO S.67E-04 S.77E-02 

2.00E+02 1.3SE-02 1.07E-02 O.OOE+OO 1.37E-04 2. 44E-02 

3.00E+02 1.12E-02 2. 83E-03 O.OOE+OO 3. 29E-OS 1.40E-02 

4.00E+02 9.S4E-03 7.4lE-04 O.OOE+OO 7.9SE-06 1.03E-02 

S.OOE+02 B.29E-03 1. 93E-04 O.OOE+OO 1. 92E-06 8. 49E-03 

6.00E+02 7.28E-03 4.99E-OS O.OOE+OO 4.62E-07 7. 33E-03 

7.00E+02 . 6. 42E-03 1.2BE-05 O.OOE+OO 1.1lE-07 6. 44E-03 

B.OOE+02 S.6BE-03 3.29E-06 O.OOE+OO 2. 69E-OB S.68E ... 03 

9.00E+02 S.02E-03 8. 42E-07 O.OOE+OO O.OOE+OO S.02E-03 

1.OOE+03 4. 44E-03 2.lSE-07 O.OOE+OO O.OOE+OO 4. 44E-03 , '. 2.00E+03 1.30E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.30E-03 

4.00E+03 1.l2E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.l2E-04 

S.OOE+03 3.2BE-OS O.OOE+OO O.OOE+OO O.OOE+OO 3.2BE-OS 

7.00E+03 2.B3E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.B3E-06 

8.00E+03 B.29E-07 O.OOE+OO O.OOE+OO O.OOE+OO B.29E-07 

9.00E+03 2. 43E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 43E-07 

1.OOE+04 7. 13E-OB O.OOE+OO O.OOE+OO O.OOE+OO 7.l3E-08 

B-212 
CLASS V .AMAD = 1 MICRON BALFLlFE= 1.92E+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-ROUR ACCUMULATED 24-ROUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 3.35E-03 8. 47E-04 

2.00E-Ol 7.09E-03 1.83E-03 

3.00E-Ol 1.OlE-03 3.06E-03 

4.00E-Ol 1.29E-02 4. 82E-03 

5.00E-Ol 1. 57E-02 7. 33E-03 

6.00E-Ol 1.8lE-02 1.07E-02 

7.00E-Ol 2.02E-02 1. 51E-02 

8.00E-Ol 2. 23E-02 2.05E-02 

9.00E-Ol 2. 42E-02 2. 67E-02 

1.00E+OO 2. 59E-02 2. 59E-02 3. 36E-02 3. 36E-02 

2.00E+OO 1.lOE-02 3. 69E-02 8.8.7E-02 1.22E-OI 

3.00E+OO 5.l3E-03 4.21E-02 7. 33E-02 1. 95E-ol 

4.00E+OO 3.05E-03 4.50E-02 4. 26E-02 2. 38E-Ol 

5.00E+OO 2. 26E-03 4. 73E-02 2.20E-02 2.60E-Ol 

6.00E+OO 1.90E-03 4.9lE-02 1. 12E-02 2.71E-0l 

7.00E+OO 1.67E-03 5.09E-02 5. 93E-03 2. 77E-ol 

8.00E+OO 1.51E-03 5. 23E-02 3.42E-03 2.81E-Ol 

9.00E+OO 1. 38E-03 5. 37E-02 2.2lE-03 2.83E-Ol 

1.OOE+Ol 1.27E-03 5.50E-02 1. 62E-03 2.84E-Ol 

2.00E+Ol 6. 62E-04 6.35E-02 8.47E-04 2. 93E-Ol 

3.00E+Ol 4. 48E-04 6. 86E-02 7.07E-04 2.99E-Ol 

4.00E+Ol 3. 59E-04 7.22E-02 6.03E-04 3.05E-Ol 

5.00E+Ol 3.l1E-04 7. 53E-02 5.23E-04 3.09E-Ol 

6.00E+Ol 2. 78E-04 7. 79E-02 4. 55E-04 3. 13E-Ol 

7.00E+Ol 2.50E-04 8.02E-02 3. 97E-04 3. 16E-Ol 

8.00E+Ol 2. 26E-04 8. 24E-02 3. 47E-04 3.l9E-OI 

9.00E+Ol 2.05E-04 8. 42E-02 3.03E-04 3.21E-Ol 

1.00E+02 1.85E-04 8.58E-02 2. 65E-04 3.23E-Ol 

2.00E+02 6. 86E-05 9.43E-02 7.00E-05 3.25E-Ol 

3.00E+02 2.70E-05 9.52E-02 1. 95E-05 3. 17E-Ol 

4.00E+02 1.27E-05 9. 37E-02 6. 24E-06 3.07E-Ol 

5.00E+02 7. 65E-06 9.l3E-02 2. 65E-06 2. 97E-Ol 

6.00E+02 5. 63E-06 8. 87E-02 1.59E-06 2.87E-Ol 

7.00E+02 4.63E-06 8.61E-02 1.20E-06 2. 77E-Ol 

8.00E+02 3. 99E-06 8. 34E-02 1.0IE-06 2. 67E-Ol 

9.00E+02 3.50E-06 8.09E-02 8. 73E-07 2. 57E-Ol 

1.00E+03 3.09E-06 7. 83E-02 7.73E-07 2. 49E-Ol 

2.00E+03 9.03E-07 5.61E-02 2. 25E-07 1. 74E-Ol 

3.00E+03 2. 65E-07 3. 95E-02 6. 62E-08 1. 21E-0l 

4.00E+03 7. 76E-08 2.77E-02 1. 94E-08 8. 47E-02 

5.00E+03 2.27E-08 2. 24E-02 O.OOE+OO 5.90E-02 

B-213 
CLASS V AHA» - 1 MICR.OR STABLE NICDL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.08E-02 2.76E-Ol 2. 35E-Ol 5. 68E-02 6. 29E-Ol 

2.00E-Ol 5. 25E-02 2. 65E-Ol 1. 97E-Ol 1.04E-Ol 6.l9E-OI 

3.00E-0l 4. 68E-02 2.56E-0l 1.66E-0l 1. 42E-Ol 6.lOE-OI 

4.00E-Ol 4. 26E-02 2. 47E-Ol 1. 39E-Ol 1. 73E-Ol 6.03E-Ol 

5.00E-Ol 3.95E-02 2.40E-0l l.l7E-OI 1.99E-Ol 5.95E-Ol 

6.00E-Ol 3. 72E-02 2. 33E-Ol 9. 86E-02 2.l8E-OI 5.87E-Ol 

7.00E-Ol 3. 54E-02 2.27E-Ol 8. 29E-02 2.33E-Ol 5. 78E-Ol 

8.00E-Ol 3. 39E-02 2.2lE-Ol 6.97E-02 2. 43E-Ol 5. 68E-Ol 

9.00E-Ol 3. 28E-02 2.l6E-OI 5.86E-02 2.50E-Ol 5.57E-Ol 

1.OOE+OO 3. 19E-02 2.llE-OI 4.93E-02 2. 53E-Ol 5.45E-Ol 

2.00E+OO 2. 85E-02 1. 77E-Ol 8. 72E-03 1. 93E-Ol 4.07E-Ol 

3.00E+OO 2.82E-02 1.60E-Ol 1. 54E-03 1.07E-Ol 2. 97E-Ol 

4.00E+OO 2. 83E-02 1.50E-Ol 2.72E-04 5.40E-02 2. 33E-Ol 

5.00E+OO 2. 85E-02 1. 45E-Ol 4. 82E-05 2. 69E-02 2.00E-Ol 

6.00E+OO 2. 86E-02 1.41E-Ol 8.5IE-06 1. 39E-02 1.83E-Ol 

7.00E+OO 2. 88E-02 1. 38E-Ol 1.5lE-06 7.70E-03 1. 75E-Ol 

8.00E+OO 2.89E-02 1.36E-Ol 2. 66E-07 4.77E-03 1.70E-Ol 

9.00E+OO 2.9lE-02 1. 34E-Ol 4.70E-08 3. 36E-03 1. 66E-Ol 

1.OOE+Ol 2. 92E-02 1.32E-Ol O.OOE+OO 2. 67E-03 1. 64E-Ol 

2.00E+Ol 3.06E-02 1.16E-OI O.OOE+OO 1.7SE-03 1. 49E-Ol 

3.00E+Ol 3.l7E-02 1.02E-OI O.OOE+OO 1.55E-03 1.36E-O 

4.00E+Ol 3.2SE-02 9.0lE-02 O.OOE+OO 1. 35E-03 1.24E 

5.00E+Ol 3.37E-02 7. 93E-02 O.OOE+OO 1.17E-03 1.14E-O 

6.00E+Ol 3. 45E-02 6. 98E-02 O.OOE+OO 1.02E-03 1.05E-OI 

7.00E+Ol 3.52E-02 6.l4E-02 O.OOE+OO S.90E-04 9. 75E-02 

S.OOE+Ol 3.58E-02 5.40E-02 O.OOE+OO 7. 75E-04 9.06E-02 

9.00E+Ol 3. 63E-02 4.75E-02 O.OOE+OO 6. 75E-04 S.45E-02 

1.OOE+02 3. 68E-02 4. 18E-02 O.OOE+OO 5. 87E-04 7.9lE-02 

2.00E+02 3. 83E-02 1.15E-02 O.OOE+OO 1.47E-04 4. 99E-02 

3.00E+02 3. 72E-02 3. 15E-03 O.OOE+OO 3. 67E-05 4.04E-02 

4.00E+02 3. 55E-02 S.55E-04 O.OOE+OO 9.1SE-06 3.64E-02 

5.00E+02 3. 36E-02 2.3lE-04 O.OOE+OO 2. 29E-06 3.3SE-02 

6.00E+02 3.l7E-02 6. 19E-05 O.OOE+OO 5.74E-07 3.lSE-02 

7.00E+02 3.00E-02 1. 65E-05 O.OOE+OO 1. 43E-07 3.00E-02 

8.00E+02 2. 83E-02 4.40E-06 O.OOE+OO 3.58E-OS 2.S3E-02 

9.00E+02 2. 67E-02 1.l6E-06 O.OOE+OO O.OOE+OO 2. 67E-02 

I.OOE+03 2.52E-02 3.0SE-07 O.OOE+OO O.OOE+OO 2. 52E-02 '. -: ," 2.00E+03 1.4lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.4lE-02 

4.00E+03 4. 46E-03 O.OOE+OO O.OOE+OO O.OOE+OO 4. 46E-03 

5.00E+03 2.50E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.50E-03 

7.00E+03 7. 88E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7.8SE-04 

8.00E+03 4. 43E-04 O.OOE+OO O.OOE+OO O.OOE+OO 4. 43E-04 

9.00E+03 2. 48E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 48E-04 

l.OOE+04 1. 39E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 39E-04 

2.00E+04 4. 33E-07 O.OOE+OO O.OOE+OO O.OOE+OO 4. 33E-07 

B-2l4 
CLASS W AHAD = 1 MICRON STABLE NICKEL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.OSE-02 8.06E-06 

2.00E-Ol 2.03E-02 1.62E-04 

3.00E-Ol 2.79E-02 8.l7E-04 

4.00E-Ol 3.40E-02 2. 38E-03 

S.OOE-Ol 3. 89E-02 S.16E-03 

6.00E-Ol 4.30E-02 9. 38E-03 

7.00E-Ol 4. 63E-02 1. SlE-02 

B.OOE-Ol 4.9lE-02 2. 23E-02 

9.00E-Ol S.14E-02 3.09E-02 

1.OOE+OO S.33E-02 S.33E-02 4.07E-02 4.07E-02 

2.00E+OO 8.77E-03 6.2lE-02 1.29E-Ol 1.70E-Ol 

3.00E+OO 2. 32E-03 6.44E-02 1.08E-Ol 2. 78E-Ol 

4.00E:g.g 1.OlE-03 6. S4E-02 6. 28E-02 3.4lE-Ol 

S.OOE 0 6.S2E-04 6.6lE-02 3. 23E-02 3. 73E-Ol 

6.00E+OO S.18E-04 6. 66E-02 1.6lE-02 3.89E-Ol 

7.00E+OO 4.S7E-04 6.70E-02 8. 29E-03 3. 98E-Ol 

8.00E+OO 4.26E-04 6.7SE-02 4. S7E-03 4.02E-Ol 

9.00E+OO 4.09E-04 6. 79E-02 2.8lE-03 4.0SE-Ol 

1.OOE+Ol 3. 99E-04 6. 83E-02 1.96E-03 4.07E-Ol 

2.00E+Ol 3.S8E-04 7.20E-02 1.03E-03 4.l9E-Ol 

3.00E+Ol 3.2SE-04 7.S4E-02 8.97E-04 4.28E-Ol 

4.00E+Ol 2. 96E-04 7.8SE-02 7.8lE-04 4.36E-Ol 

S.OOE+Ol 2. 69E-04 8.l3E-02 6.80E-04 4.44E-Ol 

6.00E+Ol 2.4SE-04 8. 39E-02 S.92E-04 4.S0E-Ol 

7.00E+Ol 2. 22E-04 8. 62E-02 S.lSE-04 4.SSE-Ol 

8.00E+Ol 2.02E-04 8. 83E-02 4. 48E-04 4.60E-Ol 

9.00E+Ol 1. 84E-04 9.02E-02 3.90E-04 4. 64E-Ol 

1.OOE+02 1.67E-04 9.20E-02 3.40E-04 4. 68E-Ol 

2.00E+02 6.92E-OS 1.03E-Ol 8.S0E-OS 4. 86E-Ol 

3.00E+02 3.S9E-OS 1.08E-Ol 2.l2E-OS 4.9lE-Ol 

4.00E+02 2. 48E-OS 1.l1E-Ol S.3lE-06 4.92E-Ol 

S.OOE+02 2.06E-OS 1. 13E-Ol 1. 33E-06 4. 92E-Ol 

6.00E+02 1.87E-OS 1.iSE-Ol 3.32E-07 4.92E-Ol 

7.00E+02 1. 74E-OS 1.17E-Ol 8.30E-08 4. 92E-Ol -- -, .:;-." : .(. 8.00E+02 1.64E-OS 1.18E-Ol 2.07E-08 4. 92E-Ol 

9.00E+02 1.S4E-OS 1.20E-Ol O.OOE+OO 4. 92E-Ol 

1.OOE+03 1.46E-OS 1.22E-Ol O.OOE+OO 4.92E-Ol 

2.00E+03 8.l7E-06 1.33E-Ol O.OOE+OO 4.92E-Ol 

4.00E+03 2.S8E-06 1.42E-Ol O.OOE+OO 4.92E-Ol 

8.00E+03 2.S6E-07 1.46E-Ol O.OOE+OO 4. 92E-Ol 

1.OOE+04 8.0SE-08 1.47E-Ol O.OOE+OO 4.92E-Ol 

B-2lS 
CLASS W AMAD = 1 MICRON STABLE COPPER 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.72E-02 2.76E-Ol 2.3SE-Ol S.OBE-02 6. 39E-Ol 

2.00E-Ol 9.S9E-02 2.6SE-01 1.97E-01 B.03E-02 6. 39E-01 

3.00E-01 1.lBE-Ol 2.S6E-Ol 1. 66E-01 9. B9E-02 6.3BE-01 

4.00E-Ol 1.3BE-Ol 2. 47E ... Ol 1.39E-Ol 1.l2E-Ol 6. 37E-Ol 

S.OOE-Ol 1.S6E-Ol 2.40E-Ol 1.l7E-Ol 1. 22E-Ol 6.3SE-Ol 

6.00E-Ol 1.71E-Ol 2. 33E-Ol 9.B6E-02 1.29E-Ol 6.3lE-Ol 

7.00E-Ol 1. B4E-Ol 2. 27E-Ol B.29E-02 1. 34E-Ol 6.2BE-Ol 

8.00E-01 1.9SE-Ol 2.2lE-Ol 6.97E-02 1.37E-Ol 6. 23E-01 

9.00E-01 2.0SE-01 2. 16E-Ol S.B6E-02 1.3BE-01 6. 17E-01 

1.00E+OO 2. 13E-01 2. llE-Ol 4. 93E-02 1.3BE-Ol 6.llE-Ol 

2.00E+OO 2.S3E-01 1.77E-Ol B.72E-03 9.B6E-02 5.3BE-Ol 

3.00E+OO 2.63E-01 1.60E-Ol 1.S4E-03 S.3BE-02 4.7BE-Ol 

4.00E+OO 2.65E-Ol 1.S0E-Ol 2.72E-04 2.70E-02 4.42E-01 

S.OOE+OO 2. 63E-Ol 1.4SE-Ol 4.B2E-OS 1.3SE-02 4. 22E-01 

6.00E+OO 2.6lE-Ol 1.4lE-Ol B.SIE-06 6.9BE-03 4.09E-Ol 

7.00E+OO 2.SBE-Ol 1.3BE-Ol 1.SlE-06 3. 92E-03 4.00E-Ol 

B.OOE+OO 2.SSE-Ol 1.36E-Ol 2. 66E-07 2.46E-03 3. 94E-"Ol 

9.00E+OO 2.S2E-01 1. 34E-Ol 4.70E-OB 1. 76E-03 3.BBE-Ol 

1.OOE+Ol 2.49E-01 1.32E-Ol O.OOE+OO 1.4lE-03 3.B2E-Ol 

2.00E+Ol 2.l9E-Ol 1.l6E-Ol O.OOE+OO 9.S7E-04 3. 36E-Ol 

3.00E+Ol 1.92E-01 1.02E-Ol O.OOE+OO B.33E-04 2.9SE-Ol 

4.00E+Ol 1.69E-Ol 9.0lE-02 O.OOE+OO 7.2SE-04 2.60E-O 

S.OOE+Ol 1.4BE-Ol 7.93E-02 O.OOE+OO 6.3lE-04 2.2BE-01 

6.00E+01 1.3lE-Ol 6.9BE-02 O.OOE+OO S.SOE-04 2.0lE-Ol 

7.00E+01 1.lSE-Ol 6. 14E-02 O.OOE+OO 4.7BE-04 1. 77E-Ol 

B.OOE+Ol 1.OlE-Ol S.40E-02 O.OOE+OO 4.l7E-04 1.S6E-Ol 

9.00E+Ol B.9lE-02 4. 75E-02 O.OOE+OO 3. 63E-04 1.37E-Ol 

1.OOE+02 7.B4E-02 4.lBE-02 O.OOE+OO 3. 16E-04 1.2lE-Ol 

2.00E+02 2. 22E-02 1.lSE-02 O.OOE+OO 7.B9E-OS 3.3BE-02 

3.00E+02 6. 33E-03 3.lSE-03 O.OOE+OO 1.97E-OS 9.S0E-03 

4.00E+02 1.BOE-03 B.SSE-04 O.OOE+OO 4. 93E-06 2. 66E-03 

S.OOE+02 S.OBE-04 2.3lE-04 O.OOE+OO 1. 23E-06 7.40E-04 

6.00E+02 1.42E-04 6.l9E-OS O.OOE+OO 3.0BE-07 2.04E-04 

7.00E+02 3.9SE-OS 1.6SE-OS O.OOE+OO 7.71E-OB S.6lE-OS 

B.OOE+02 1.09E-OS 4.40E-06 O.OOE+OO 1. 93E-OB 1.S3E-OS 

9.00E+02 2. 97E-06 1.16E-06 O.OOE+OO O.OOE+OO 4.l4E-06 

1.00E+03 B.07E-07 3.0BE-07 O.OOE+OO O.OOE+OO 1.llE-06 

B-2l6 
CLASS W AMAD ... 1 MICRON STABLE COPPER 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.08E-04 7. 37E-06 

2.00E-Ol 2. 57E-04 1. 37E-04 

3.00E-Ol . 4. 42E-04 6.46E-04 

4.00E-Ol 6. 64E-04 1. 78E-03 

5.00E-Ol 9. 19E-04 3. 68E-03 

6.00E-Ol 1.20E-03 6. 43E-03 

7.00E-Ol 1.51E-03 1.00E-02 

8.00E-Ol 1. 84E-03 1. 44E-02 

9.00E-Ol 2. 19E-03 1.95E-02 

1.00E+00 2. 55E-03 2. 55E-03 2. 52E-02 2. 52E-02 

2.00E+00 4. 12E-03 6.67E-03 6. 94E-02 9. 46E-02 

3.00E+00 4.49E-03 1. 12E-02 5. 52E-02 1.50E-Ol 

4.00E+00 4. 58E-03 1. 57E-02 3. 14E-02 1.81E-01 

5.00E+00 4. 58E-03 2.03E-02 1.60E-02 1.97E-Ol 

6.00E+00 4. 55E-03 2. 49E-02 8.02E-03 2.05E-01 

7.00E+00 4.50E-03 2. 94E-02 4. 14E-03 2.09E-Ol 

8.00E+00 4. 45E-03 3. 38E-02 2.30E-03 2. 12E-Ol 

9.00E+00 4. 39E-03 3. 82E-02 1. 43E-03 2. 13E-Ol 

1.00E+01 4. 34E-03 4.25E-02 1.01E-03 2. 14E-Ol 

2.00E+01 3.81E-03 8.30E-02 5. 42E-04 2.20E-Ol 

3.00E+01 3. 35E-03 1. 19E-01 4.72E-04 2.25E-Ol 

4.00E+01 2. 94E-03 1.50E-Ol 4. l1E-04 2. 30E-0 1 

5.00E+01 2. 59E-03 1.77E-01 3. 57E-04 2. 34E-Ol 

6.00E+01 2. 28E-03 2.01E-Ol 3. l1E-04 2. 37E-01 

7.00E+01 2.00E-03 2.23E-Ol 2.71E-04 2.40E-Ol 

8.00E+01 1. 76E-03 2.41E-Ol 2. 36E-04 2. 42E-Ol 

9.00E+01 1.55E-03 2. 58E-Ol 2.05E-04 2.44E-Ol 

1.00E+02 1. 37E-03 2. 72E-01 1.79E-04 2. 46E-01 

2.00E+02 3. 87E-04 3.49E-01 4.47E-05 2.56E-Ol 

3.00E+02 1.10E-04 3.71E-Ol 1. 12E-05 2. 58E-Ol 

4.00E+02 3. 14E-05 3.78E-0l 2.79E-06 2.59E-Ol 

5.00E+02 8.85E-06 3. 79E-01 6. 98E-07 2. 59E-01 

6.00E+02 2. 48E-06 3.80E-01 1.75E-07 2.59E-01 

7.00E+02 6.8BE-07 3. BOE-01 4. 36E-OB 2. 59E-01 .. ... 

, . B.00E+02 1. B9E-07 3. BOE-01 1.09E-OB 2. 59E-Ol 

9.00E+02 5.1BE-OB 3.80E-Ol O.OOE+OO 2. 59E-01 

1.00E+03 1.41E-OB 3. BOE-01 O.OOE+OO 2. 59E-01 

B-217 
CLASS W AMAD :::: 1 MICRON STABLE GALLIUM 69 

TIME AFTER. FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.97E-02 2.76E-Ol 2.35E-Ol 5.72E-02 6. 38E-Ol 

2.00E-Ol 6. 84E-02 2. 65E-Ol 1. 97E-Ol 1.05E-01 6.36E-Ol 

3.00E-Ol 6.72E-02 2.56E-Ol 1. 66E-Ol 1.45E-Ol 6. 34E-Ol 

4.00E-Ol 6 .. 60E-02 2.47E-OI 1.39E-01 1. 79E-Ol 6.3lE-01 

5.00E-Ol 6.50E-02 2.40E-Ol 1.17E-01 2.06E-Ol 6. 27E-OI 

6.00E-Ol 6. 39E-02 2. 33E-Ol 9. 86E-02 2. 27E-OI 6.22E-Ol 

7.00E-OI 6.30E-02 2.27E-Ol 8.29E-02 2. 43E-Ol 6.15E-Ol 

8.00E-Ol 6.2lE-02 2.2lE-01 6. 97E-02 2. 54E-Ol 6.07E-Ol 

9.00E-Ol 6.l3E-02 2.l6E-0l 5.86E-02 2.6lE-0l 5.97E-0l 

1.00E+00 6.05E-02 2.11E-Ol 4. 93E-02 2. 65E-Ol 5. 86E-Ol 

2.00E+00 5.49E-02 1.77E-OI 8.72E-03 2.03E-OI 4.44E-Ol 

3.00E+00 5.l9E-02 I.60E-Ol 1. 54E-03 1.l3E-OI 3.27E-Ol 

4.00E+00 5.03E-02 I.SOE-OI 2.72E-04 5.72E-02 2. 58E-Ol 

5.00E+00 4.93E-02 1. 45E-Ol 4. 82E-05 2. 85E-02 2. 22E-OI 

6.00E+00 4.86E-02 1.4lE-01 8.SIE-06 1. 47E-02 2.04E-OI 

7.00E+00 4.8IE-02 1.38E-01 1.SlE-06 8.l3E-03 1. 94E-Dl 

8.00E+00 4.77E-02 1.36E-01 2. 66E-07 S.03E-03 1. 89E-Ol 

9.00E+00 4. 73E-02 1. 34E-Ol 4.70E-08 3.S4E-03 1.8SE-01 

1.00E+Ol 4.70E-02 I.32E-Ol O.OOE+OO 2.8lE-03 1.82E-01 

2.00E+Ol 4. 39E-02 1.16E-OI O.OOE+OO 1. 87E-03 1.62E-01 

3.00E+Ol 4.09E-02 1.02E-01 O.OOE+OO 1. 63E-03 1.4 

4.00E+Ol 3.80E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1. 29E-0 

5.00E+Ol 3. 53E-02 7.93E-02 O.OOE+OO 1.23E-03 1.16E-01 

6.00E+Ol 3. 27E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.04E-01 

7.00E+Ol 3.03E-02 6.l4E-02 O.OOE+OO 9.3SE-04 9. 26E-02 

8.00E+0l 2.80E-02 S.40E-02 O.OOE+OO 8.l4E-04 8. 28E-02 

9.00E+Ol 2. S8E-02 4 .• 7SE-02 0.00£+00 7.09E-04 7.40E-02 

1.00E+02 2. 38E-02 4.l8E-02 O.OOE+OO 6.l7E-04 6. 62E-02 

2.00E+02 9.80E-03 1.lSE-02 O.OOE+OO 1. S4E-04 2.ISE-02 

3.00E+02 3. 67E-03 3.lSE-03 O.OOE+OO 3. 86E-OS 6. 86E-03 

4.00E+02 1. 29E-03 8. SSE-04 O.OOE+OO 9.64E-06 2.l6E-03 

S.00E+02 4. 32E-04 2.3lE-04 O.OOE+OO 2.4lE-06 6.6SE-04 

6.00E+02 l.39E-04 6.l9E-05 O.OOE+OO 6.03E-07 2.02E-04 

7.00E+02 4. 37E-OS l.65E-05 O.OOE+OO l.5lE-07 6.04E-05 

8.00E+02 1. 34E-05 4.40E-06 O.OOE+OO 3.77E-08 l.78E-OS 

9.00E+02 4.04E-06 l.16E-06 O.OOE+OO O.OOE+OO 5.20E-06 

1.00E+03 1.20E-06 3.08E-07 O.OOE+OO O.OOE+OO l.50E-06 

B-2l8 
CLASS V AMAD "'" 1 KICR.ON STABLE GALLIUM 69 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.29E-03 8.l0E-06 

2.00E-Ol 2.70E-03 1. 64E-04 

3.00E-Ol 4.03E-03 8.29E-04 

4.00E-Ol 5.27E-03 2. 42E-03 

5.00E-Ol 6. 44E-03 5.2~E-03 

6.00E-Ol 7. 53E-03 9.6lE-03 

7.00E-Ol 8.56E-03 1.55E-02 

8.00E-Ol 9. 53E-03 2.30E-02 

9.00E-Ol 1.04E-02 3.l9E-02 

1.OOE+OO 1. 13E-02 1.13E-02 4.21E-02 4.2lE-02 

2.00E+OO 6.20E-03 1. 75E-02 1.35E-Ol 1.77E-Ol 

3.00E+OO 3. 52E-03 2.lOE-02 1.14E-Ol 2. 92E:-Ol 

4.00E+OO 2.l8E-03 2. 32E-02 6.64E-02 3. 58E-Ol 

5.00E+OO 1.50E-03 2. 47E-02 3.4lE-02 3. 92E-Ol 

6.00E+OO 1.16E-03 2.58E-02 1.71E-02 4.09E-Ol 

7.00E+OO 9. 82E-04 2. 68E-02 8.77E-03 4.l8E-Ol 

8.00E+OO 8.9lE-04 2.77E-02 4.83E-03 4.23E-Ol 

9.00E+OO 8. 43E-04 2.86E-02 2. 96E-03 4. 26E-Ol 

1.OOE+Ol 8.l6E-04 2. 94E-02 2.07E-03 4. 28E-Ol 

2.00E+Ol 7. 39E-04 3.70E-02 1.08E-03 4.40E-Ol 

3.00E+Ol 6.85E-04 4.4lE-02 9. 43E-04 4.50E-Ol 

4.00E+Ol 6. 35E-04 5.07E-02 8.2lE-04 4. 59E-Ol 

5.00E+Ol 5. 87E-04 5. 68E-02 7.l5E-04 4. 67E-Ol 

6.00E+Ol 5. 42E-04 6. 24E-02 6. 22E-04 4. 73E-Ol 

7.00E+Ol 4. 99E-04 6. 76E-02 5. 42E-04 4. 79E-Ol 

8.00E+Ol 4.60E-04 7. 23E-02 4. 72E-04 4. 84E-Ol 

9.00E+Ol 4.22E-04 7. 67E-02 4. llE-04 4. 88E-Ol 

1.OOE+02 3. 88E-04 8.08E-02 3. 57E-04 4. 92E-Ol 

2.00E+02 1. 55E-04 1.06E-Ol 8. 94E-05 5.llE-Ol 

3.00E+02 5.70E-05 1.16E-Ol 2. 23E-05 5.l6E-Ol 

4.00E+02 1.97E-05 1.20E-Ol 5.59E-06 5.l7E-Ol 

5.00E+02 6. 53E-06 1.2lE-0l 1.40E-06 5.l8E-Ol 

6.00E+02 2.09E-06 1.2lE-Ol 3. 49E-07 5.l8E-Ol 

7.00E+02 6.50E-07 1.21E-Ol 8. 73E-08 5.l8E-Ol ... 

.. .', . 8.00E+02 1. 98E-07 1.2lE-Ol 2.18E-08 5.l8E-Ol 

9.00E+02 5. 94E-08 1.2lE-0l O.OOE+OO 5.l8E-Ol 

1.OOE+03 1. 75E-08 1.2lE-0l O.OOE+OO 5.l8E-Ol 

B-2l9 
CLASS W .AMAD = 1 MICRON STABLE ARSENIC 75 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7.07E-02 2. 76E-Ol 2.3SE-Ol S.OSE-02 6.32E-Ol 

2.00E-Ol 8.lSE-02 2.6SE-Ol 1. 97E-Ol S.03E-02 6.2SE-Ol 

3.00E-Ol 9. S3E-02 2. S6E-Ol 1.66E-01 9.S9E-02 6.l6E-01 

4.00E-Ol 1.07E-01 2.47E-Ol 1. 39E-Ol 1.12E-01 6.06E-Ol 

S.OOE-Ol 1.16E-01 2.40E-Ol 1.17E-01 1.22E-01 S.9SE-Ol 

6.00E-Ol 1.22E-01 2. 33E-Ol 9.S6E-02 1.29E-01 S.83E-Ol 

7.00E-Ol 1.27E-01 2.27E-Ol S.29E-02 1. 34E-Ol S.70E-Ol 

S.OOE-Ol 1.30E-01 2.2lE-01 6.97E-02 1.37E-01 S.S7E-Ol 

9.00E-Ol 1.3lE-01 2.l6E-01 S.S6E-02 1.3SE-01 S.44E-Ol 

1.00E+00 1.32E-01 2.l1E-01 4. 93E-02 1.3SE-01 S.30E-Ol 

2.00E+00 1.22E-01 1.77E-01 S.72E-03 9.S6E-02 4.07E-Ol 

3.00E+00 1.OSE-01 1.60E-01 1.S4E-03 S.3SE-02 3.23E-Ol 

4.00E+00 9.64E-02 1. SOE-Ol 2.72E-04 2.70E-02 2. 74E-Ol 

S.OOE+OO S.7SE-02 1.4SE-01 4.S2E-OS 1.3SE-02 2.46E-Ol 

6.00E+00 S.OSE-02 1.4lE-01 S.SlE-06 6.9SE-03 2.29E-Ol 

7.00E+00 7.SlE-02 1.3SE-01 1.SlE-06 3. 92E-03 2.l7E-01 

S.OOE+OO 7.00E-02 1. 36E-Ol 2.66E-07 2. 46E-03 2.0SE-Ol 

9.00E+00 6.SSE-02 1.34E-01 4.70E-OS 1. 76E-03 2.0lE-01 

1.00E+Ol 6.l4E-02 1.32E-01 O.OOE+OO 1.4lE-03 1.9SE-01 

2.00E+Ol 3.37E-02 1.16E-01 O.OOE+OO 9.S7E-04 1.SlE-01 

3.00E+Ol 1.9SE-02 1.02E-01 O.OOE+OO S.33E-04 1.23E-01 

4.00E+Ol 1.22E-02 9.0lE-02 O.OOE+OO 7.2SE-04 1.03E-01 

S.OOE+Ol S.2lE-03 7.93E-02 O.OOE+OO 6.3lE-04 S.SlE-02 

6.00E+Ol S.99E-03 6.9SE-02 O.OOE+OO S.SOE-04 7. 63E-02 

7.00E+Ol 4.67E-03 6.l4E-02 O.OOE+OO 4.7SE-04 6.6SE-02 

S.OOE+Ol 3.SlE-03 S.40E-02 O.OOE+OO 4.l7E-04 S.S2E-02 

9.00E+Ol 3.22E-03 4.7SE-02 O.OOE+OO 3.63E-04 S.l1E-02 

1.00E+02 2.77E-03 4.lSE-02 O.OOE+OO 3.l6E-04 4. 49E-02 

2.00E+02 7. 79E-04 1.lSE-02 O.OOE+OO 7.S9E-OS 1.24E-02 

3.00E+02 2. 23E-04 3.lSE-03 O.OOE+OO 1.97E-OS 3. 39E-03 

4.00E+02 6.2SE-OS S.SSE-04 O.OOE+OO 4. 93E-06 9.23E-04 

S.00E+02 1.7SE-OS 2.3lE-04 O.OOE+OO 1.23E-06 2. 49E-04 

6.00E+02 4.SlE-06 6.l9E-OS O.OOE+OO 3.0SE-07 6.70E-OS 

7.00E+02 1.3lE-06 1.6SE-OS O.OOE+OO 7.71E-OS 1. 79E-OS 

S.00E+02 3.SSE-07 4.40E-06 O.OOE+OO 1. 93E-OS 4.77E-06 

9.00E+02 9.SSE-08 1.16E-06 O.OOE+OO O.OOE+OO 1.26E-06 

1.00E+03 2.S7E-OS 3.0SE-07 O.OOE+OO O.OOE+OO 3. 33E-07 

B-220 
CLASS 11 .AHAD = 1 MICRON STABLE ARSENIC 75 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------~----------------------------------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6. 67E-03 7.37E-06 

2.00E-Ol 1.44E-02 1. 37E-04 

3.00E-Ol 2. 27E-02 6. 46E-04 

4.00E-Ol 3.l6E-02 1. 78E-03 

5.00E-Ol 4.08E-02 3.68E-03 

6.00E-Ol 5.00E-02 6.43E-03 

7.00E-Ol 5.90E-02 1.OOE-02 

8.00E-Ol 6.77E-02 1. 44E-02 

9.00E-Ol 7.59E-02 1.95E-02 

1.OOE+OO 8. 36E-02 8. 36E-02 2. 52E-02 2. 52E-02 

2.00E+OO 5. 44E-02 1. 38E-Ol 6.94E-02 9.46E-02 

J.OOE+OO 2. 85E-02 1.67E-Ol 5. 52E-02 1.50E-Ol 

4.00E+~ 1. 74E-02 1.84E-Ol 3.l4E-02 1.8lE-Ol 

5.00E+ 1.20E-02 1. 96E-Ol 1.60E-02 1.97E-Ol 

6.00E+OO 9.i3E-OJ 2.05E-Ol 8.02E-03 2.05E-Ol 

7.00E+OO 7.45E-OJ 2. 13E-Ol 4.l4E-03 2.09E-Ol 

8.00E+OO 6.4lE-03 2.l9E-Ol 2.30E-03 2.l2E-Ol 

9.00E+OO 5. 72E-03 2. 25E-Ol 1.4JE-03 2.i3E-Ol 

1.OOE+Ol 5. 23E-OJ 2.30E-Ol 1.OlE-03 2.l4E-Ol 

2.00E+Ol 2. 96E-03 2. 68E-Ol 5. 42E-04 2.20E-Ol 

3.00E+Ol 1.89E-03 2.91E-Ol 4.72E-04 2. 25E-Ol 

4.00E+Ol 1.30E-OJ 3.06E-Ol 4. llE-04 2.30E-Ol 

5.00E+Ol 9. 69E-04 3.17E-0l 3.57E-04 2. 34E-Ol 

6.00E+Ol 7. 66E-04 3. 26E-Ol J.llE-04 2. 37E-Ol 

7.00E+Ol 6. 33E-04 3. 33E-Ol 2.7lE-04 2.40E-Ol 

8.00E+Ol 5. 37E-04 3. 39E-Ol 2. 36E-04 2.42E-Ol 

9.00E+Ol 4. 64E-04 3. 44E-Ol 2.05E-04 2. 44E-Ol 

1.OOE+02 4.05E-04 3. 48E-Ol 1. 79E-04 2. 46E-Ol 

2.00E+02 1.16E-04 3. 71E-Ol 4.47E-05 2. 56E-Ol 

3.00E+02 3. 32E-05 3. 77E-Ol lol2E-05 2. 58E-Ol 

4.00E+02 9. 34E-06 3.79E-Ol 2. 79E-06 2.59E-Ol 

5.00E+02 2. 59E-06 3.80E-Ol 6. 98E-07 2. 59E-Ol 

6.00E+02 7.14E-07 3.80E-Ol 1.75E-07 2. 59E-Ol 

7.00E+02 1. 95E-07 3.80E-Ol 4. 36E-08 2. 59E-Ol 

8.00E+02 5. 27E-08 3.80E-Ol 1.09E-08 2. 59E-Ol 

9.00E+02 1.42E-08 3.80E-Ol O.OOE+OO 2. 59E-Ol 

B-22l 
CLASS W AHAD = 1 KICR.ON STABLE SELENIUM 78 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

.1.00E-Ol B.83E-02 2. 76E-Ol 2.35E-Ol 3.96E-02 6. 39E-Ol 

2.00E-Ol 1.26E-Ol 2. 65E-Ol 1.97E-Ol 4. 96E-02 6. 38E-Ol 

3.00E-Ol 1.62E-Ol 2. 56E-Ol 1.66E-Ol 5. 37E-02 6.3BE-Ol 

4.00E-Ol 1. 93E-Ol 2. 47E-Ol 1. 39E-Ol 5. 64E-02 6. 36E-Ol 

5.00E-Ol 2.20E-Ol 2.40E-Ol 1.17E-OI 5.84E-02 6. 35E-Ol 

6.00E-Ol 2. 42E-Ol 2. 33E-Ol 9. 86E-02 5. 96E-02 6.33E-Ol 

7.00E-Ol 2.61E-0l 2. 27E-Ol 8.29E-02 6.02E-02 6.30E-Ol 

B.OOE-Ol 2. 17E-Ol 2.2lE-Ol 6. 97E-02 6.02E-02 6. 28E-Ol 

9.00E-Ol 2.9lE-Ol 2.l6E-0l 5. 86E-02 5.98E-02 6.25E-01 

1.OOE+OO 3.02E-Ol 2.11E-Ol 4. 93E-02 5.89E-02 6.2lE-Ol 

2.00E+OO 3.57E-Ol 1. 77E-Ol 8.12E-03 3.95E-02 5. 83E-Ol 

3.00E+OO 3.69E-01 1.60E-Ol 1. 54E-03 2. 12E-02 5.5lE-Ol 

4.00E+OO 3. 69E-Ol 1.50E-Ol 2.72E-04 1.06E-02 5.30E-Ol 

5.00E+OO 3. 65E-Ol 1. 45E-Ol 4. 82E-05 5.30E-03 5.l5E-Ol 

6.00E+OO 3.6lE-Ol 1.4lE-Ol 8.51E-06 2. 77E-03 5.05E-0l 

7.00E+OO 3. 56E-Ol 1. 38E-Ol 1.5lE-06 1. 57E-03 4. 96E-Ol 

8.00E+OO 3.52E-Ol 1.36E-Ol 2. 66E-07 1.00E-03 4. 89E-Ol 

9.00E+OO 3.48E-Ol 1. 34E-Ol 4.70E-08 7. 29E-04 4. 82E-Ol 

1.OOE+Ol. 3. 44E-Ol 1.32E-Ol O.OOE+OO 5. 93E-04 4.76E-Ol 

2.00E+Ol 3.l3E-Ol 1. 16E-Ol O.OOE+OO 4.09E-04 4.30E-Ol 

3.00E+Ol 2.9lE-Ol 1.02E-OI O.OOE+OO 3.56E-04 3.93E-Ol 

4.00E+Ol 2.11E-Ol 9.0lE-02 O.OOE+OO 3.l0E-04 3. 62E-Ol 

5.00E+Ol 2. 54E-Ol 7. 93E-02 O.OOE+OO 2.70E-04 3.34E-Ol 

6.00E+Ol 2. 39E-Ol 6. 98E-02 O.OOE+OO 2. 35E-04 3.09E-Ol 

7.00E+Ol 2.26E-Ol 6.l4E-02 O.OOE+OO 2.04E-04 2. 87E-Ol 

8.00E+Ol 2.l3E-Ol 5.40E-02 O.OOE+OO 1. 78E-04 2. 67E-Ol 

9.00E+Ol 2.02E-Ol 4.75E-02 O.OOE+OO 1.55E-04 to 50E-Ol 

1.OOE+02 1. 92E-Ol 4. 18E-02 O.OOE+OO 1.35E-04 2. 34E-Ol 

2.00E+02 1.19E-Ol 1. 15E-02 O.OOE+OO 3. 37E-05 1.3lE-Ol 

3.00E+02 7. 57E-02 3. 15E-03 O.OOE+OO 8.43E-06 7. 89E-02 

4.00E+02 4.80E-02 8.55E-04 O.OOE+OO 2.llE-06 4. 88E-02 

5.00E+02 3.03E-02 2.3lE-04 O.OOE+OO 5. 27E-07 3.05E-02 

6.00E+02 1.9lE-02 6. 19E-05 O.OOE+OO 1. 32E-07 1. 92E-02 

7.00E+02 1.20E-02 1. 65E-05 O.OOE+OO 3. 29E-08 1.21E-02 

8.00E+02 7.58E-03 4.40E-06 O.OOE+OO O.OOE+OO 7. 59E-03 

9.00E+02 4. 78E-03 l.l6E-06 O.OOE+OO O.OOE+OO 4.7BE-03 

1.OOE+03 3.0lE-03 3.0BE-07 O.OOE+OO O.OOE+OO 3.01E-03 

2.00E+03 2. 97E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2. 97E-05 

3.00E+03 2.92E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2. 92E-07 

B-222 
CLASS W AHA» - 1 MICRON STABLE SELENIUM. 78 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2. 28E-04 S.74E-06 

2.00E-Ol S.94E-04 9.0lE-OS 

3.00E-Ol 1.O'9E-03 3. 78E-04 

4.00E-Ol 1. 69E-03 9.6lE-04 

S.OOE-Ol 2. 38E-OJ 1. 88E-OJ 

6.00E-Ol 3.l4E-03 3.l5E-03 

7.00E-Ol J.97E-OJ 4.75E-03 

8.00E-Ol 4.8SE-03 6.6SE-OJ 

9.00E-Ol S.77E-OJ 8. 82E-03 

1.OOE+OO 6. 72E-03 6. 72E-OJ 1.12E-02 1.12E-02 

2.00E+OO 1.03E-02 1.70E-02 2.80E-02 3. 92E-02 

3.00E+OO 1.OlE-02 2.71E-02 2.l6E-02 6.08E-02 

4.00E+OO 9.26E-03 3. 63E-02 1. 22E-02 7.30E-02 

S.OOE+QO 8.J9E-03 4.47E-02 6.l9E-03 7.9lE-02 

6.00E+OO 7.6lE-OJ S.2JE-02 3.lOE-03 8. 22E-02 

7.00E+OO 6. 94E-03 S.93E-02 l.60E-03 8. 38E-02 

8.00E+OO 6. 38E-03 6. 56E-02 8.9SE-04 8. 47E-02 

9.00E+OO S.9lE-03 7.l6E-02 S.S9E-04 8.S3E-02 

1.OOE+Ol S.S3E-03 7.7lE-02 3. 97E-04 8.S7E-02 

2.00E+Ol 3. 82E-03 1.2lE-Ol 2.l7E-04 8.8lE-02 

J.OOE+Ol J.23E-03 1. S6E-Ol 1. 89E-04 9.02E-02 

4.00E+Ol 2. 82E-03 1. 86E-Ol 1. 64E-04 9.l9E-02 

S.OOE+Ol 2. 49E-OJ 2.l2E-Ol 1. 43E-04 9. 34E-02 

6.00E+Ol 2.2lE-OJ 2. JSE-Ol 1. 24E-04 9. 48E-02 

7.00E+Ol 1.98E-OJ 2.S6E-Ol 1.08E-04 9.S9E-02 

8.00E+Ol 1. 78E-03 2.7SE-Ol 9. 43E-OS 9. 69E-02 

9.00E+Ol 1.6lE-03 2. 92E-Ol 8.2lE-OS 9. 78E-02 

l.OOE+02 l.46E-OJ J.07E-Ol 7.l4E-OS 9. 85E-02 

2.00E+02 6. 79E-04 4.06E-Ol 1. 79E-OS 1.02E-Ol 

J.OOE+02 J.8JE-04 4.S7E-Ol 4. 46E-06 1.03E-Ol 

4.00E+02 2.3lE-04 4.87E-Ol 1.12E-06 1.04E-Ol 

5.00E+02 1.4JE-04 S.OSE-Ol 2. 79E-07 1.04E-Ol 

6.00E+02 8.9lE-05 S.16E-0l 6.98E-08 1.04E-Ol 

7.00E+02 S.S9E-05 S.2JE-Ol 1. 74E-08 1.04E-Ol 

8.00E+02 J.52E-OS S.28E-Ol O.OOE+OO 1.04E-Ol 

9.00E+02 2.2lE-05 S.JlE-Ol O.OOE+OO 1.04E-Ol 

1.OOE+OJ 1.J9E-OS S.J2E-Ol O.OOE+OO 1.04E-0l 

2.00E+03 l.J7E-07 S.35E-Ol O.OOE+OO 1.04E-Ol 

B-223 
CLASS W AHAD = 1 MICRON STABLE BROMINE 79 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 1.07E-Ol 2.76E-0l 2.35E-Ol 2.lOE-02 6. 39E-Ol 

2.00E-Ol 1. 55E-Ol 2. 65E-Ol 1.97E-Ol 1. 96E-02 6.3BE;;'Ol 

3.00E-Ol 1.9BE-Ol 2. S6E-0l 1.66E-Ol 1.6BE-02 6. 36E-Ol 

4.00E-Ol 2. 34E-Ol 2. 47E-Ol 1.39E-Ol 1.43E-02 6. 35E-OI 

5.00E-Ol 2. 64E-Ol 2.40E-0l 1.l7E-OI 1.22E-02 6. 33E-Ol 

6.00E-Ol 2.B9E-Ol 2. 33E-Ol 9.B6E-02 1.OSE-02 6.3lE-Ol 

7.00E-Ol 3.11E-0l 2. 27E-Ol B.29E-02 9.01E-03 6. 29E-Ol 

B.OOE-Ol 3. 29E-Ol 2.2IE-Ol 6. 97E-02 7.77E-03 6. 27E-Ol 

9.00E-Ol 3.44E-Ol 2. 16E-0l 5.B6E-02 6.72E-03 6. 25E-Ol 

1.OOE+OO 3. 56E-Ol 2.11E-Ol 4. 93E-02 S.B3E-03 6.22E-Ol 

2.00E+OO 4.0BE-Ol 1.77E-Ol B.72E-03 1. 66E-03 5.9SE-Ol 

3.00E+OO 4.05E-Ol 1.60E-Ol 1. 54E-03 6. 39E-04 S.67E-Ol 

4.00E+OO 3.B9E-Ol 1.50E-0l 2.72E-04 3.0BE-04 S.39E-Ol 

5.00E+OO 3. 68E-Ol 1. 45E-Ol 4. 82E-OS 1. 74E-04 S.13E-OI 

6.00E+OO· 3. 47E-Ol 1.41E-0l 8.51E-06 1.12E-04 4.88E-Ol 

7.00E+OO 3.27E-Ol 1. 38E-Ol 1.5lE-06 8.l6E-OS 4.6SE-Ol 

8.00E+OO 3.07E-Ol 1. 36E-Ol 2.66E-07 6. 63E-05 4. 43E-Ol 

9.00E+OO 2.B8E-Ol 1. 34E-Ol 4.70E-08 5. 83E-05 4. 22E-Ol 

1.OOE+Ol 2.71E-Ol 1.32E-0l O.OOE+OO S.40E-05 4.03E-Ol 

2.00E+Ol 1.47E-Ol 1.16E-Ol O.OOE+OO 4. 38E-OS 2. 63E-Ol 

3.00E+OI 8. 34E-02 1.02E-Ol O.OOE+OO 3. B2E-OS 1. 86E-Ol 

4.00E+Ol 5.05E-02 9.01E-02 O.OOE+OO 3. 32E-05 1.4lE-Ol 

5.00E+Ol 3.30E-02 7. 93E-02 O.OOE+OO 2.89E-OS 1.12E-OI 

6.00E+Ol 2. 33E-02 6. 98E-02 O.OOE ....... OO 2. 52E-05 9.31E-02 

7.00E+Ol 1.77E-02 6.14E-02 O.OOE+OO 2.19E-05 7.91E-02 

B.OOE+OI 1.4lE-02 5.40E-02 O.OOE+OO 1.91E-05 6.81E-02 

9.00E+OI 1. 17E-02 4. 75E-02 O.OOE+OO 1. 66E-05 5. 92E-02 

1.00E+02 9. 95E-03 4.18E-02 O.OOE+OO 1.45E-OS 5.1BE-02 

2.00E+02 2. 64E-03 1.lSE-02 O.OOE+OO 3.61E-06 1.42E-02 

3.00E+02 7.27E-04 3.15E-03 O.OOE+OO 9.04E-07 3. 88E-03 

4.00E+02 1.99E-04 B.55E-04 O.OOE+OO 2. 26E-07 1.05E-03 

5.00E+02 5. 39E-05 2.31E-04 O.OOE+OO 5. 65E-OB 2.8SE-04 

6.00E+02 1.45E-05 6.19E-05 O.OOE+OO 1.41E-08 7.64E-05 

7.00E+02 3.90E-06 1.65E-05 O.OOE+OO O.OOE+OO 2.04E-05 

8.00E+02 I.04E-06 4.40E-06 O.OOE+OO O.OOE+OO 5. 44E-06 

9.00E+02 2. 76E-07 1.16E-06 O.OOE+OO O.OOE+OO 1. 44E-06 

1.OOE+03 7.32E-08 3.0BE-07 O.OOE+OO O.OOE+OO 3.81E-07 

B-224 
CLASS W AMAD = 1 MICRON STABLE BR.OMINE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol S.19E-04 6.90E-ll 

2.00E-Ol 1. 43E-03 7.29E-lO 

3.00E-Ol 2.66E-03 2.60E-09 

4.00E-Ol 4.l6E-03 6.0SE-09 

S.OOE-Ol S.B9E-03 1.12E-OB 

6.00E-Ol 7.BlE-03 1.BlE-OB 

7.00E-Ol 9.B9E-03 2. 67E-OB 

B.OOE-Ol 1.2lE-02 3. 67E-OB 

9.00E-Ol 1.44E-02 4. 79E-OB 

1.OOE+OO 1. 69E-02 1. 69E-02 6.02E-OB 6.02E-OB 

2.00E+OO 2.70E-02 4. 39E-02 1.40E-07 2.00E-07 

3.00E+OO 2.B3E-02 7.22E-02 1.06E-07 3.07E-07 

4.00E+OO 2.7SE-02 9. 97E-02 S.9SE-OB 3. 66E-07 

S.OOE+OO 2. 62E-02 1.26E-Ol 3.02E-OB 3. 96E-07 

6.00E+OO 2.4BE-02 1.SlE-Ol 1. SlE-OB 4.l2E-07 , 

7.00E+OO 2. 34E-02 1.74E-Ol O.OOE+OO 4.l9E-07 

B.OOE+OO 2.20E-02 1.96E-Ol O.OOE+OO 4.24E-07 

9.00E+OO 2.06E-02 2.l7E-Ol O.OOE+OO 4. 27E-07 

1.OOE+Ol 1. 94E-02 2. 36E-Ol O.OOE+OO 4. 29E-07 

2.00E+Ol 1.OSE-02 3. 76E-Ol O.OOE+OO 4.4lE-07 

3.00E+Ol S.94E-03 4.S3E-Ol O.OOE+OO 4.SlE-07 

4.00E+Ol 3.SBE-03 4.99E-Ol O.OOE+OO 4.60E-07 

S.OOE+Ol 2. 33E-03 S.27E-Ol O.OOE+OO 4. 67E-07 

6.00E+Ol l.64E-03 S.46E-Ol O.OOE+OO 4.74E-07 

7.00E+Ol 1. 24E-03 S.60E-Ol O.OOE+OO 4. BOE-07 

B.OOE+Ol 9.BBE-04 S.7lE-Ol O.OOE+OO 4.BSE-07 

9.00E+Ol B.19E-04 S.BOE-Ol O.OOE+OO 4.B9E-07 

1.OOE+02 6.9SE-04 S.B7E-Ol O.OOE+OO 4. 93E-07 

2.00E+02 1. B4E-04 6.2SE-Ol O.OOE+OO S.12E-07 

3.00E+02 S.07E-OS 6.3SE-Ol O.OOE+OO S.17E-07 

4.00E+02 1. 39E-OS 6.3BE-Ol O.OOE+OO S.lBE-07 

S.OOE+02 3. 76E-06 6.39E-Ol O.OOE+OO S.lBE-07 

6.00E+02 1.OlE-06 6.39E-Ol O.OOE+OO S.lBE-07 

7.00E+02 2.72E-07 6.39E-Ol O.OOE+OO S.lBE-07 

" B.OOE+02 7.2SE-OB 6.39E-Ol O.OOE+OO S.lBE-07 

9.00E+02 1.93E-OB 6.39E-Ol O.OOE+OO S.lBE-07 

B-22S 
CLASS W AHA» = 1 MICRON lIALFLIFE= 1.47E+OO DAYS BROMINE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 1.02E-Ol 2. 64E-Ol 2.24E-Ol 2.00E-02 6.09E-Ol 

2.00E-Ol 1.4lE-Ol 2.4lE-Ol 1.80E-Ol 1. 79E-02 S.80E-Ol 

3.00E-Ol 1. 72E-Ol 2. 22E-Ol 1.44E-Ol 1.46E-02 S.S3E-Ol 

4.00E-Ol 1. 94E-Ol 2.0SE-Ol 1.16E-Ol 1.19E-02 S.26E-Ol 

S.OOE-Ol 2.09E-Ol 1.89E-Ol 9. 27E-02 9. 67E-03 S.OOE-Ol 

6.00E-Ol 2.l8E-Ol 1.7SE-Ol 7.43E-02 7.90E-03 4. 76E-oi 

7.00E-Ol 2. 23E-Ol 1. 63E-Ol S.96E-02 6. 48E-03 4. 52E-Ol 

8.00E-Ol 2.2SE-Ol 1.SlE-Ol 4. 78E-02 S.33E-03 4.30E-Ol 

9.00E-Ol 2.2SE-Ol 1.4lE-Ol 3.84E-02 4. 39E-03 4.09E-0l 

1.OOE+OO 2.22E-Ol 1.32E-Ol 3.08E-02 3. 64E-03 3. 88E-Ol 

2.00E+OO 1.S9E-Ol 6.90E-02 3.40E-03 6. 48E-04 2. 32E-Ol 

3.00E+OO 9. 84E-02 3. 88E-02 3.7SE-04 1. SSE-04 1.38E-Ol 

4.00E+OO S.89E-02 2.28E-02 4.13E-OS 4. 66E-OS 8.l8E-02 

S.OOE+OO 3. 49E-02 1. 37E-02 4.S6E-06 1. 64E-OS 4. 86E-02 

6.00E+OO 2.0SE-02 8. 32E-03 S.03E-07 6.60E-06 2. 88E-02 

7.00E+OO 1.20E-02 S.09E-03 S.SSE-08 3.0lE-06 1.7lE-02 

8.00E+OO 7.06E-03 3.l3E-03 O.OOE+OO 1.S2E-06 1.02E-02 

9.00E+OO 4.l4E-03 1. 92E-03 O.OOE+OO 8.37E-07 6.06E-03 

I.OOE+Ol 2. 43E-03 1.18E-03 O.OOE+OO 4 .• 83E-07 3.6lE-03 

2.00E+Ol 1.18E-OS 9.32E-06 O.OOE+OO O.OOE+OO 2.llE-OS 

3.00E+Ol S.99E-08 7.3SE-08 O.OOE+OO O.OOE+OO 1.33E-07 

B-226 
CLASS W AHAD == 1 MICRON HALFLIFE= 1.47E+OO DAYS BK.OMINE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-OI 4. 95E-04 6.SSE-ll 

2.00E-Ol 1.30E-03 6.64E-I0 

3.00E-Ol 2.31E-03 2. 26E-09 

4.00E-Ol 3.44E-03 5.01E-09 

5.00E-Ol 4.6SE-03 S.S7E-09 

6.00E-Ol S.SSE-03 1. 37E-OS 

7.00E-Ol 7.llE-03 1.92E-OS 

S.OOE-Ol S.30E-03 2. 52E-OS 

9.00E-Ol 9.45E-03 3.14E-OS 

1.OOE+OO 1.05E-02 1.05E-02 3. 76E-OS 3. 76E-OS 

2.00E+OO 1.05E-02 1. 71E-02 5. 46E-OS 7.S0E-OS 

3.00E+OO 6.S7E-03 1. 75E-02 2.5SE-OS 7.45E-OS 

4.00E+OO 4.1SE-03 1.51E-02 O.OOE+OO 5. 55E-OS 

5.00E+OO 2.4SE-03 1.19E-02 O.OOE+OO 3. 75E-OS 

6.00E+OO 1.46E-03 S.90E-03 O.OOE+OO 2. 43E-OS 

7.00E+OO S.61E-04 6. 42E-03 O.OOE+OO 1.55E-OS 

S.OOE+OO 5.05E-04 4.51E-03 O.OOE+OO 9. 75E-09 

9.00E+OO 2.96E-04 3.llE-03 O.OOE+OO 6.12E-09 

1.OOE+Ol 1.74E-04 2.11E-03 O.OOE+OO 3.S4E-09 

2.00E+Ol S.41E-07 3.02E-05 O.OOE+OO 3. 54E-ll 

B-227 
CLASS W AHA» - 1 MICIlOB STABLE lftRIUM. 89 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 6. 72E-02 2.76E-Ol 2.35E-Ol 5.72E-02 6. 35E-Ol 

2.00E-0l 6.40E-02 2. 65E-Ol 1. 97E-Ol 1.05E-Ol 6. 32E-Ol 

3.00E-Ol 6.15E-02 2. 56E-Ol 1.66E-Ol 1.46E-Ol 6. 29E-Ol 

4.00E-0l 5. 95E-02 2.47E-Ol 1. 39E-Ol 1. 79E-Ol 6. 25E-Ol 

5.00E-Ol 5.81E-02 2.40E-Ol 1.17E-0l 2.06E-Ol 6.21E-0l 

6.00E-Ol 5.70E-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6.l5E-Ol 

7.00E-Ol 5. 62E-02 2.27E-Ol 8. 29E-02 2.43E-Ol 6.08E-Ol 

8.00E-Ol 5. 56E-02 2.2lE-Ol 6. 97E-02 2. 54E-Ol 6.00E-Ol 

9.00E-Ol 5. 52E-02 2.l6E-Ol 5. 86E-02 2.6lE-Ol 5.91E-Ol 

1.OOE+OO 5. 49E-02 2.11E-Ol 4. 93E-02 2. 65E-Ol 5.80E-Ol 

2.00E+OO 5. 42E-02 1.77E-Ol 8.72E-03 2.04E-Ol 4. 44E-Ol 

3.00E+OO 5. 45E-02 1.60E-Ol 1. 54E-03 1.l3E-Ol 3. 29E-Ol 

4.00E+OO 5. 49E-02 1.50E-Ol 2. 72E-04 5.72E-02 2. 63E-Ol 

5.00E+OO 5. 52E-02 1. 45E-Ol 4. 82E-05 2. 85E-02 2. 28E-Ol 

6.00E+OO 5. 56E-02 1.4lE-OI 8.51E-06 1. 47E-02 2.11E-0l 

l.OOE+OO 5.60E-02 1. 38E-Ol 1.5lE-06 8. 14E-03 2.02E-Ol 

8.00E+OO 5. 63E-02 1.36E-0l 2. 66E-07 5.04E-03 1.97E-Ol 

9.00E+OO 5. 67E-02 1.34E-Ol 4.70E-08 3. 55E-03 1. 94E-Ol 

1.00E+Ol 5.70E-02 1.32E-Ol O.OOE+OO 2. 82E-03 1.92E-0l 

2.00E+Ol 6.04E-02 1. 16E-Ol O.OOE+OO 1.B7E-03 1.7BE-Ol 

3.00E+Ol 6. 35E-02 1.02E-OI O.OOE+OO 1. 63E-03 1.67E-O 

4.00E+Ol 6. 62E-02 9.01E-02 O.OOE+OO 1.42E-03 1. 

5.00E+Ol 6.8BE-02 7.93E-02 O.OOE+OO 1.24E-03 1.49E-O 

6.00E+Ol 7.10E-02 6.9BE-02 O.OOE+OO 1.08E-03 1.42E-Ol 

7.00E+Ol 7.31E-02 6.14E-02 O.OOE+OO 9.36E-04 1.35E-Ol 

B.OOE+Ol 7.49E-02 5.40E-02 O.OOE+OO 8.l5E-04 1.30E-OI 

9.00E+Ol 7. 66E-02 4. 75E-02 O.OOE+OO 7.09E-04 1.25E-Ol 

1.00E+02 7.81E-02 4.18E-02 O.OOE+OO 6.l8E-04 1.21E-Ol 

2.00E+02 B.67E-02 1. 15E-02 O.OOE+OO 1.54E-04 9. 84E-02 

3.00E+02 8. 95E-02 3.15E-03 O.OOE+OO 3.B6E-05 9. 27E-02 

4.00E+02 9.03E-02 8.55E-04 O.OOE+OO 9.65E-06 9. 12E-02 

5.00E+02 9.06E-02 2.31E-04 O.OOE+OO 2.41E-06 9.08E-02 

6.00E+02 9.06E-02 6.19E-05 O.OOE+OO 6.03E-07 9.0lE-02 

7.00E+02 9.07E-02 l.65E-05 O.OOE+OO l.5lE-Ol 9.07E-02 

8.00E+02 9.07E-02 4.40E-06 O.OOE+OO 3. 77E-OB 9.0lE-02 

9.00E+02 9.07E-02 1. 16E-06 O.OOE+OO O.OOE+OO 9.07E-02 , . 

,. 1.OOE+03 9.07E-02 3.0BE-07 O.OOE+OO O.OOE+OO 9.07E-02 

2.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

4.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

5.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

7.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

8.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

l.OOE+04 9.0lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.0lE-02 

2.00E+04 9.0lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.0lE-02 

B-228 
CLASS W AHAD = 1 MICllO.N STABLE Yl"l'lUUM 89 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.74E-03 B.lOE-06 

2.00E-Ol 7.l3E-03 1.64E-04 

3.00E-Ol 9.7lE-03 B.29E-04 

4.00E-Ol 1.17E-02 2.42E-03 

S.OOE-Ol 1. 32E-02 S.2BE-03 

6.00E-Ol 1.43E-02 9.6ZE-03 

7.00E-Ol I.SIE-02 1. SSE-02 

B.OOE-Ol 1.5BE-02 2.30E-02 

9.00E-Ol 1. 63E-02 3. 19E-02 

1.00E+OO 1. 67E-02 1.67E-02 4. 22E-02 4.22E-02 

2.00E+OO l.22E-03 1. 79E-02 1.3SE-Ol 1.7BE-OI 

3.00E+OO l.96E-04 1. BIE-02 1. 14E-Ol 2. 92E-Ol 

4.00E+OO 1.31E-04 I.B2E-02 6. 65E-02 3.5BE-Ol 

5.00E+OO 1.2SE-04 1.B3E-02 3.4ZE-02 3. 92E-Ol 

6.00E+OO 1. 24E-04 I.B5E-OZ 1.71E-02 4.lOE-OI 

7.00E+OO 1.22E-04 I.B6E-OZ B.7BE-03 4.1BE-Ol 

B.OOE+OO 1. ZlE-04 1.B7E-02 4. B4E-03 4.23E-Ol 

9.00E+OO 1.20E-04 1. BBE-02 2. 97E-03 4.Z6E-Ol 

1.OOg+Ol 1.19E-04 1.90E-02 2.07E-03 4.2BE-Ol 

2.00E+Ol 1.0BE-04 2.01E-02 1.09E-03 4. 41E-0l 

3.00E+Ol 9. BlE-OS 2.11E-02 9.44E-04 4.51E-Ol 

4.00E+Ol B.B9E-05 2.20E-02 B.22E-04 4.S9E-Ol 

S.OOE+Ol B.04E-OS 2. 29E-02 7.16E-04 4.67E-Ol 

6.00E+Ol 7. 27E-OS 2. 36E-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol 6.S6E-05 2. 43E-02 5. 42E-04 4.79E-Ol 

B.OOE+Ol S.9lE-05 2.49E-02 4. 72E-04 4.B4E-Ol 

9.00E+Ol 5. 32E-05 2.5SE-02 4.11E-04 4.B9E-Ol 

1.OOE+02 4.7BE-OS 2.60E-02 3.5BE-04 4. 93E-Ol 

2.00E+02 1.57E-OS 2.B9E-02 B.94E-05 5.l2E-OI 

3.00E+02 4.BBE-06 2.9BE-02 2. 24E-05 5.l7E-0l 

4.00E+02 1. 46E-06 3.01E-02 5. 59E-06 S.lBE-Ol 

5.00E+02 4. 23E-07 3.02E-02 1.40E-06 5.lBE-Ol 

6.00E+02 1.21E-07 3.D2E-02 3. 49E-07 S.lBE-OI 

7.00E+02 3. 39E-OB 3.02E-02 B.73E-OB 5.1BE-ol , . , ,., 

B-229 
CLASS W AHAD == 1 MICRON IlA.LFLIFE= 5.85£+01 DAYS Tl"lR.IDK 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE·INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 6.72E-02 2. 76E-Ol 2.34E-Ol 5.71E-02 6. 35E-Ol 

2.00E-Ol 6. 38E-02 2. 65E-Ol 1.97E-01 1.05E-Ol 6.30E-Ol 

3.00E-Ol 6. 12E-02 2. 55E-01 1. 65E-01 1. 45E-Ol 6.26E-01 

4.00E-Ol 5. 93E-02 2. 46E-01 1.39E-01 1. 78E-01 6. 22E-Ol 

5.00E-01 5. 78E-02 2.38E-01 1. 17E-01 2.04E-01 6. 17E-Ol 

6.00E-01 5. 66E-02 2. 31E-Ol 9.79E-02 2. 25E-01 6. 11E-Ol 

7.00E-01 5. 58E-02 2. 25E-01 8. 23E-02 2. 41E-01 6.03E-Ol 

8.00E-01 5. 51E-02 2. 19E-Ol 6. 91E-02 2. 52E-01 5. 95E-Ol 

9.00E-01 5.46E-02 2. 13E-01 5.80E-02 2.59E-01 5. 85E-Ol 

1.00E+00 5.42E-02 2.08E-01 4. 87E-02 2. 62E-01 5. 73E-01 

2.00E+00 5. 29E-02 1.73E-01 8.51E-03 1.99E-01 4.33E-Ol 

3.00E+00 5. 26E-02 1. 54E-01 1.49E-03 1.09E-Ol 3. 18E-01 

4.00E+00 5.23E-02 1. 43E-Ol 2.60E-04 5. 46E-02 2.50E-Ol 

5.00E+00 5.20E-02 1.36E-Ol 4. 54E-05 2. 68E-02 2.; 15E-01 

6.00E+00 5. 18E-02 1.31E-01 7.93E-06 1.37E-02 1.97E-Ol 

7.00E+00 5. 15E-02 1.27E-01 1. 39E-06 7. 49E-03 1. 86E-Ol 

8.00E+00 5. 12E-02 1.24E-01 2. 42E-07 4. 58E-03 1. 79E-Ol 

9.00E+OO 5.09E-02 1.20E-01 4. 23E-08 3. 19E-03 1.75E-01 

1.00E+Ol 5.07E-02 1. 17E-01 O.OOE+OO 2.50E-03 1.71E-01 

2.00E+01 4.77E-02 9. 17E-02 O.OOE+OO 1. 48E-03 1.41E-01 

3.00E+Ol 4. 45E-02 7. 17E-02 O.OOE+OO 1.14E-03 1.t7E-01 

4.00E+01 4.12E-02 5.61E-02 O.OOE+OO 8. 83E-04 9. 82E-0 

5.00E+01 3.80E-02 4.38E-02 O.OOE+OO 6.83E-04 8. 25E-02 

6.00E+Ol 3. 49E-02 3. 43E-02 O.OOE+OO 5. 28E-04 6. 97E-02 

7.00E+Ol 3. 19E-02 2. 68E-02 O.OOE+OO 4.08E-04 5. 91E-02 

8.00E+01 2.90E-02 2.09E-02 O.OOE+OO 3. 16E-04 5.03E-02 

9.00E+01 2. 64E-02 1.64E-02 O.OOE+OO 2. 44E-04 4.30E-02 

1.00E+02 2. 39E-02 1. 28E-02 O.OOE+OO 1. 89E-04 3. 69E-02 

2.00E+02 8.llE-03 1.08E-03 O.OOE+OO 1. 44E-05 9.20E-03 

3.00E+02 2. 56E-03 9.02E-05 O.OOE+OO 1.1OE-06 2. 65E-03 

4.00E+02 7.90E-04 7. 48E-06 O.OOE+OO 8. 44E-08 7. 98E-04 

5.00E+02 2. 42E-04 6. 17E-07 O.OOE+OO O.OOE+OO 2. 43E-04 

6.00E+02 7. 42E-05 5.07E-08 O.OOE+OO O.OOE+oo 7. 42E-05 

7.00E+02 2.27E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2. 27E-05 

8.00E+02 6. 94E-06 O.OOE+OO O.OOE+OO O.OOE+OO 6. 94E-06 

9.00E+02 2. 12E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2. 12E-06 

1.00E+03 6. 49E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 49E-07 

B-230 
CLASS V AHAD = 1 MICRON BALFLlFE= 5.85E+OI DAYS Y'lTRIUH 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-01 3.73E-03 B.09E-06 

2.00E-01 7.UE-03 1.63E-04 

3.00E-01 9. 67E-03 B.26E-04 

4.00E-01 1.16E-02 2.41E-03 

S.OOE-01 1.31E-02 S.2SE-03 

6.00E-01 1. 42E-02 9.SSE-03 

7.00E-01 I.S0E-02 I.S4E-02 

B.OOE-01 I.S6E-02 2.2BE-02 

9.00E-Ol 1. 61E-02 3. 16E-02 

1.00E+OO 1.6SE-02 1.6SE-02 4. 17E-02 4. 17E-02 

2.00E+OO 1. 19E-03 1. 75E-02 1.32E-01 1.73E-0l 

3.00E+OO 1.B9E-04 1.7SE-02 1.10E-01 2. 82E-Ol 

4.00E2 1. 24E-04 1. 74E-02 6. 34E-02 3.42E-Ol 

S.OOE 0 1. 18E-04 1. 73E-02 3. 22E-02 3.70E-Q1 

6.00E+OO 1.1SE-04 1.72E-02 1. S9E-02 3.BIE-0l 

7.00E+OO 1. 13E-04 1.71E-02 8.08E-03 3. 85E-01 

B.OOE+OO 1.10E-04 1.70E-Q2 4.40E-03 3.8SE-01 

9.00E+OO 1.0BE-04 1. 69E-02 2. 67E-03 3. 83E-01 

1.00E+01 1.06E-04 1.6BE-02 1.84E-03 3. BOE-01 

2.00E+01 8.S3E-OS 1.S8E-02 8. 56E-04 3. 48E-Ol 

3.00E+01 6. 88E-OS 1.48E-02 6. 62E-04 3. 16E-Ol 

4.00E+01 S.54E-OS 1. 37E-02 S.12E-04 2. 86E-01 

S.OOE+01 4.4SE-OS 1.27E-02 3.96E-04 2.5BE-01 

6.00E+01 3.S7E-05 1. 16E-02 3.06E-04 2. 33E-01 

7.00E+01 2.B6E-OS 1.06E-02 2.37E-04 2.09E-0l 

B.OOE+01 2. 29E-05 9.67E-03 1.83K-04 1.8BE-Ol 

9.00E+01 1. 83E-OS 8.7BE-03 1.42E-04 1.6BE-Ol 

1.00E+02 1. 46E-OS 7.9SE-03 1.09E-04 1.SlE-01 

2.00E+02 1. 47E-06 2.70E-03 8. 37E-06 4. 79E-02 

3.00E+02 1.40E-07 8.S3E-04 6.40E-07 1.4BE-02 

4.00E+02 1. 27E-OB 2. 63E-04 4. 89E-08 4. 53E-03 

"'" 

B-231 
CLASS W AHA» == 1 MICRON STABLE ZIRCONIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7.07E-02 2.76E-01 2.35E-01 5. 71E-02 6. 39E-01 

2.00E-01 7.05E-02 2. 65E-01 1. 97E-Ol 1.05E-01 6. 38E-01 

3.00E-01 7.03E-02 2. 56E-01 1.66E-Ol 1.45E-Ol 6.37E-01 

4.00E-Ol 7.01E-02 2. 47E-01 1.39E-01 1. 79E-01 6. 35E-01 

5.00E-01 6. 99E-02 2.40E-01 1. 17E-01 2.05E-01 6.32E-01 

6.00E-Ol 6. 96E-02 2. 33E-01 9. 86E-02 2. 26E-01 6.28E-01 

7.00E-Ol 6.94E-02 2. 27E-01 8. 29E-02 2.42E-01 6.21E-01 

8.00E-Ol 6. 92E-02 2. 21E-01 6. 97E-02 2. 54E-Ol 6. 13E-01 

9.00E-Ol 6.90E-02 2. 16E-01 5. 86E-02 2.61E-01 6.04E-01 

1.00E+00 6. 87E-02 2.llE-01 4. 93E-02 2. 65E-01 5. 94E-01 

2.00E+00 6. 63E-02 1.77E-01 8.72E-03 2.03E-01 4. 55E-01 

3.00E+00 6.41E-02 1.60E-Ol 1.54E-03 1. 13E-Ol 3. 39E-01 

4.00E+00 6.20E-02 1.50E-01 2.72E-04 5.71E-02 2.70E-0l 

5.00E+00 6.01E-02 1.45E-Ol 4. 82E-05 2. 84E-02 2. 33E-Ol 

6.00E+00 5.84E-02 1.41E-01 8. 51E-06 1.46E-02 2. 14E-01 

7.00E+00 5. 69E-02 1. 38E-01 1. 51E-06 8. 12E-03 2.03E-01 

8.00E+00 5.56E-02 1.36E-Ol 2. 66E-07 5.03E-03 1. 96E-01 

9.00E+00 5. 44E-02 1. 34E-01 4.70E-08 3. 54E-03 1. 92E-01 

1.00E+Ol 5. 33E-02 1.32E-01 O.OOE+OO 2.8lE-03 1. 88E-Ol 

2.00E+01 4. 76E-02 1. 16E-01 O.OOE+OO 1.87E-03 1.66E-01 

3.00E+01 4.65E-02 1.02E-01 O.OOE+OO 1. 63E-03 1.50E-01 

4.00E+01 4. 71E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1.39E-01 

5.00E+01 4.81E-02 7.93E-02 O.OOE+OO 1.23E-03 1.29E-01 

6.00E+01 4. 93E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.20E-01 

7.00E+01 5.04E-02 6. 14E-02 O.OOE+OO 9. 34E-04 1. 13E-01 

8.00E+01 5. 14E-02 5.40E-02 O.OOE+OO 8. 13E-04 1.06E-Ol 

9.00E+01 5. 24E-02 4. 75E-02 O.OOE+OO 7.08E-04 1/.01E-Ol 

1.00E+02 5. 32E-02 4. 18E-02 O.OOE+OO 6. 16E-04 9. 56E-02 

2.00E+02 5. 78E-02 1. 15E-02 O.OOE+OO 1.54E-04 6. 95E-02 

3.00E+02 5. 89E-02 3. 15E-03 O.OOE+OO 3. 85E-05 6.21E-02 

4.00E+02 5. 88E-02 8.55E-04 O.OOE+OO 9. 63E-06 5. 97E-02 

5.00E+02 5. 85E-02 2. 31E-04 O.OOE+OO 2.41E-06 5. 87E-02 

6.00E+02 5.80E-02 6. 19E-05 O.OOE+OO 6.02E-07 5.81E-02 

7.00E+02 5. 75E-02 1. 65E-05 O.OOE+OO 1.50E-07 5. 75E-02 

8.00E+02 5.70E-02 4.40E-06 O.OOE+OO 3. 76E-08 5.70E-02 

9.00E+02 5. 65E-02 1. 16E-06 O.OOE+OO O.OOE+OO 5. 65E-02 ., '. ' , 1.00E+03 5. 61E-02 3.08E-07 O.OOE+OO O.OOE+OO 5.61E-02 

2.00E+03 5. 14E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 14E-02 

4.00E+03 4. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 32E-02 

5.00E+03 3. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 96E-02 

7.00E+03 3. 33E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 33E-02 

8.00E+03 3.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.06E-02 

1.00E+04 2. 57E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 57E-02 

2.00E+04 1.08E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.08E-02 

B-232 
CLASS W AHAD == 1 HICKON STABLE ZIRCONIUM: 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.00E-04 8.l0E-06 

2.00E-Ol 6.47E-04 1. 64E-04 

3.00E-Ol 9. 92E-04 8. 28E-04 

4.00E-Ol 1. 33E-03 2. 42E-03 

S.OOE-Ol 1.67E-03 5.27E-03 

6.00E-Ol 2.0lE-03 9.6lE-03 

7.00E-Ol 2. 34E-03 1.55E-02 

8.00E-Ol 2. 67E-03 2.30E-02 

9.00E-Ol 3.00E-03 3.l9E-02 

1.OOE+OO 3. 33E-03 3. 33E-03 4.2lE-02 4.2lE-02 

2.00E+OO 3.l0E-03 6.4JE-03 I.35E-0l I.77E-Ol 

3.00E+OO 2. 84E-03 9. 27E-03 1.14E-Ol 2.9lE-OI 

4.00E+OO 2.60E-03 1.I9E-02 6.63E-02 3. 58E-OI 

S.OOE+OO 2. 38E-03 1. 43E-02 3.4IE-02 3.92E-Ol 

6.00E+OO 2.I8E-03 1. 64E-02 I.71E-02 4.09E-Ol 

7.00E+OO 2.00E-03 I.84E-02 8. 76E-03 4.l8E-Ol 

8.00E+OO 1.83E-03 2.0JE-02 4. 83E-03 4.22E-OI 

9.00E+OO 1. 68E-03 2.l9E-02 2. 96E-03 4.25E-Ol 

I.OOE+Ol 1.S5E-03 2. 35E-02 2.06E-03 4.27E-Ol 

2.00E+Ol 7.I9E-04 3. 38E-02 1.08E-03 4.40E-0l 

3.00E+Ol 3. 98E-04 3.89E-02 9.42E-04 4.50E-OI 

4.00E+Ol 2. 67E-04 4.2IE-02 8.20E-04 4. 58E-Ol 

5.00E+Ol 2.07E-04 4. 44E-02 7.I4E-04 4. 66E-Ol 

6.00E+Ol 1. 75E-04 4. 63E-02 6. 22E-04 4. 73E-Ol 

7.00E+OI 1. 54E-04 4. 79E-02 5.4lE-04 4.78E-0l 

8.00E+OI 1. 38E-04 4. 94E-02 4.71E-04 4. 84E-Ol 

9.00E+Ol 1. 24E-04 5.07E-02 4.l0E-04 4. 88E-Ol 

I.OOE+02 1.12E-04 5.I8E-02 3. 57E-04 4.92E-Ol 

2.00E+02 4.05E-05 5. 88E-02 8. 93E-05 5.l1E-0l 

3.00E+02 1. 62E-05 6.l4E-02 2. 23E-05 5.l6E-Ol 

4.00E+02 B.4IE-06 6. 26E-02 5. 58E-06 5.l7E-Ol 

5.00E+02 6.03E-06 6.3JE-02 1. 39E-06 5.l7E-Ol 

6.00E+02 5.30E-06 6 .. 38E-02 3. 49E-07 5.l7E-0l 

7.00E+02 5.06E-06 6.43E-02 8. 72E-OB 5.l7E-Ol 

8.00E+02 4. 96E-06 6. 48E-02 2.IBE-OB 5.l7E-0l 

9.00E+02 4.90E-06 6. 53E-02 O.OOE+OO 5.l7E-OI 

I.OOE+03 4.B6E-06 6. 58E-02 O.OOE+OO 5.17E-OI 

2.00E+03 4. 45E-06 7.05E-02 O.OOE+OO 5.17E-Ol 

4.00E+03 3. 74E-06 7.86E-02 O.OOE+OO 5.l7E-Ol 

B.OOE+03 2. 65E-06 9.l3E-02 O.OOE+OO 5.17E-OI 

I.OOE+04 2. 23E-06 9. 62E-02 O.OOE+OO 5.17E-OI 

B-233 
CLASS W AHAD ... 1 KICRON STABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7.07E-02 2.76E-01 2. 35E-Ol 5.71E-02 6. 39E-01 

2.00E-01 7.07E-02 2. 65E-Ol 1.97E-Ol 1.05E-OI 6.38E-Ol 

3.00E-01 7.06E-02 2. 56E-Ol 1.66E-01 1.45E-0l 6.37E-01 

4.00E-01 7.06E-02 2. 47E-01 1. 39E-01 1. 78E-01 6.35E-01 

5.00E-OI 7.06E-02 2.40E-01 1.17E-01 2.04E-01 6. 32E-OI 

6.00E-01 7.06E-02 2. 33E-01 9. 86E-02 2. 25E-01 6.27E-OI 

7.00E-OI 7.06E-02 2.27E-01 8.29E-02 2.4IE-Ol 6.2IE-Ol 

8.00E-01 7.05E-02 2. 21E-01 6. 97E-02 2. 52E-01 6.13E-01 

9.00E-0l 7.03E-02 2. 16E-01 5. 86E-02 2.59E-01 6.04E-OI 

1.00E+OO 7.02E-02 2.11E-01 4. 93E-02 2. 63E-01 S.93E-01 

2.00E+OO 6. 79E-02 1.17E-01 8. 12E-03 2. OlE-Ol 4.5SE-01 

3.00E+OO 6. 52E-02 1.60E-01 1. 54E-03 1. 12E-01 3. 39E-01 

4.00E+OO 6.27E-02 1.50E-01 2. 72E-04 5. 66E-02 2.70E-Ol 

5.00E+OO 6.04E-02 1. 45E-01 4. 82E-05 2. 82E-02 2. 33E-01 

6.00E+OO S.84E-02 1. 41E-0l 8.51E-06 1.4SE-02 2. 14E-01 

7.00E+OO 5.65E-02 1. 38E-Ol 1.51E-06 8.05E .... 03 2.03E-01 

8.00E+OO 5.49E-02 1.36E-Ol 2. 66E-07 4.99E-03 1. 96E-OI 

9.00E+OO 5. 35E-02 1. 34E-01 4.70E-08 3. 51E-03 I. 91E-01 

1.OOE+OI 5. 22E-02 1.32E-0l O.OOE+OO 2. 79E-03 1.87E-01 

2.00E+01 4. 53E-02 1. 16E-01 O.OOE+OO 1. 85E-03 1. 63E-Ol 

3.00E+01 4. 34E-02 1.02E-Ol O.OOE+OO 1.61E-03 1.47E-O 

4.00E+01 4.30E-02 9.01E-02 O.OOE+OO 1.40E-03 I. 34E-O 

5.00E+01 4.29E-02 7.93E-02 O.OOE+OO 1. 22E-03 1.23E-O 

6.00E+01 4. 28E-02 6. 98E-02 O.OOE+OO I.06E-03 I. 14E-OI 

7.00E+Ol 4. 26E-02 6.14E-02 O.OOE+OO 9.27E-04 I.05E-Ol 

8.00E+01 4. 23E-02 5.40E-02 O.OOE+OO 8.07E-04 9.71E-02 

9.00E+01 4. 19E-02 4. 75E-02 O.OOE+OO 7.02E-04 9.0lE-02 

1.00E+02 4. 14E-02 4.18E-02 O.OOE+OO 6.12E-04 8. 38E-02 

2.00E+02 3. 37E-02 1.15E-02 O.OOE+OO 1.S3E-04 4.S4E-02 

3.00E+02 2. 52E-02 3. 15E-03 O.OOE+OO 3. 82E-05 2. 84E-02 

4.00E+02 1. 82E-02 8.55E-04 O.OOE+OO 9.56E-06 1.91E-02 

5.00E+02 1.30E-02 2. 31E-04 O.OOE+OO 2. 39E-06 1. 33E-02 

6.00E+02 9. 24E-03 6. 19E-05 O.OOE+OO 5.97E-07 9.30E-03 

7.00E+02 ·6. 54E-03 1.65E-05 O.OOE+OO 1. 49E-07 6. 56E-03 

8.00E+02 4. 62E-03 4.40E-06 O.OOE+OO 3.13E-08 4. 63E-03 

9.00E+02 3. 27E-03 1. 16E-06 O.OOE+OO O.OOE+OO 3. 27E-03 

1.OOE+03 2.31E-03 3.08E-07 O.OOE+OO O.OOE+OO 2.31E-03 

2.00E+03 7. 19E-05 O.OOE+OO O.OOE+OO O.OOE+OO 7. 19E-OS 

3.00E+03 2. 24E-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.24E-06 

4.00E+03 6. 96E-08 O.OOE+OO O.OOE+OO O.OOE+OO 6. 96E-08 

B-234 
CLASS W AlIAD = 1 HICItOli STABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-Ol 3.6lE-04 8.09E-06 

2.00E-Ol 7.8IE-04 1. 64E-04 

3.00E-OI I.20E-03 8.27E-04 

4.00E-Ol I.61E-03 2.4IE-03 

5.00E-OI 2.02E-03 5. 26E-03 

6.00E-OI 2. 43E-03 9. 57E-03 

7.00E-OI 2. 84E-03 1. 54E-02 

8.00E-OI 3. 25E-03 2. 29E-02 

9.00E-OI 3. 65E-03 3.17E-02 

I.OOE+OO 4.05E-03 4.05E-03 4.19E-02 4.19E-02 

2.00E+OO 3.8IE-03 7. 86E-03 1. 34E-OI I.76E-OI 

3.00E+OO 3.47E-03 I.I3E-02 I.13E-OI 2. 89E-OI 

4.00E+OO 3.14E-03 I.45E-02 6.57E-02 3. 55E-OI 

5.00E+OO 2. 85E-03 I.73E-02 3. 38E-02 3.89E-OI 

6.00E+OO 2. 58E-03 I.99E-02 I.69E-02 4.06E-OI 

7.00E+OO 2. 34E-03 2. 22E-02 8. 68E-03 4.14E-OI 

8.00E+OO 2.13E-03 2. 44E-02 4.78E-03 4.19E-OI 

9.00E+OO 1. 94E-03 2. 63E-02 2. 93E-03 4. 22E-OI 

I.OOE+OI I.17E-03 2.8IE-02 2.05E-03 4.24E-OI 

2.00E+OI 8.07E-04 3. 96E-02 I.07E-03 4. 36E-OI 

3.00E+OI 4.93E-04 4. 56E-02 9. 35E-04 4.46E-OI 

4.00E+OI 3. 82E-04 4. 99E-02 8.14E-04 4. 55E-OI 

5.00E+OI 3. 36E-04 5. 34E-02 7.08E-04 4.62E-OI 

6.00E+OI 3.lOE-04 5. 66E-02 6.17E-04 4. 69E-OI 

7.00E+OI 2.9IE-04 5.96E-02 5. 37E-04 4. 75E-OI 

8.00E+OI 2. 75E-04 6. 24E-02 4. 67E-04 4.80E-OI 

9.00E+OI 2.6IE-04 6.5IE-02 4.07E-04 4. 84E-OI 

I.OOE+02 2. 47E-04 6. 76E-02 3. 54E-04 4. 88E-OI 

2.00E+02 1.5IE-04 8.70E-02 8. 86E-05 5.07E-OI 

3.00E+02 9.82E-05 9. 92E-02 2.2IE-05 5. 12E-01 

4.00E+02 6. 66E-05 1.07E-01 5. 53E-06 5.13E-01 

5.00E+02 4. 62E-05 1.l3E-Ol 1. 38E-06 5.13E-OI 

6.00E+02 3. 24E-05 1.17E-0l 3.46E-07 5. 13E-OI 

7.00E+02 2. 28E-05 1. 19E-OI 8.65E-08 5.13E-01 

8.00E+02 1.61E-05 1.21E-01 2. 16E-08 5. 13E-01 

9.00E+02 1. 14E-05 1.23E-OI O.OOE+OO 5. 13E-0l 

1.00E+03 8.03E-06 1.24E-01 O.OOE+OO 5.13E-01 

2.00E+03 2.50E-07 I. 26E-01 O.OOE+OO 5. 13E-01 

B-235 
CLASS V AHAD = 1 MICRON HALFLIFE= 3.52E+Ol DAYS NIOBIUM 9S 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL Gl TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 7.06E-02 2. 76E-Ol 2. 34E-OI S.70E-02 6.37E-Ol 

2.00E-Ol 7.04E-02 2. 64E-Ol 1. 96E-Ol I.OSE-OI 6.36E-Ol 

3.00E-Ol 7.02E-02 2.S4E-Ol 1.6SE-Ol 1. 44E-Ol 6. 33E-OI 

4.00E-Ol 7.01E-02 2.4SE-OI l.38E-OI 1. 76E-Ol 6.30E-OI 

S.OOE-Ol 7.00E-02 2.37E-Ol 1.16E-OI 2.02E-Ol 6.26E-Ol 

6.00E-OI 6. 98E-02 2.30E-Ol 9.7SE-02 2. 22E-OI 6.20E-Ol 

7.00E-Ol 6. 96E-02 2.23E-Ol 8.18E-02 2. 38E-Ol 6.12E-Ol 

8.00E-Ol 6.94E-02 2.17E-Ol 6.87E-02 2. 48E-Ol 6.03E-Ol 

9.00E-Ol 6.91E-02 2.12E-Ol S.76E-02 2.SSE-Ol S.93E-0l 

1.OOE+OO 6.88E-02 2.07E-Ol 4. 84E-02 2.S8E-Ol S.82E-OI 

2.00E+OO 6. S3E-02 1.70E-OI 8. 38E-03 1.94E-OI 4. 38E-Ol 

3.00E+OO 6.ISE-02 1.SlE-OI 1.4SE-03 1.06E-Ol 3.19E-OI 

4.00E+OO S.79E-02 1. 39E-Ol 2.S2E-04 S.23E-02 2.49E-Ol 

S.OOE+OO S.47E-02 1.31E-OI 4. 36E-OS 2.S5E-02 2.11E-Ol 

6.00E+OO S.18E-02 1.2SE-OI 7.56E-06 1.29E-02 1.90E-Ol 

7.00E+OO 4. 92E-02 1.20E-OI 1.31E-06 7.01E-03 I.77E-Ol 

8.00E+OO 4. 69E-02 1.I6E-0l 2. 27E-07 4.26E-OJ I.67E-Ol 

9.00E+OO 4.4SE-02 I.12E-OI 3. 94E-OS 2. 94E-03 1.60E-OI 

I.OOE+OI 4.28E-02 1.08E-Ol O.OOE+OO 2~29E-03 1. 54E-Ol 

2.00E+OI 3.0SE-02 7. 83E-02 O.OOE+OO I. 25E-03 1. I OE-O 1 

3.00E+OI 2.40E-02 5.66E-02 O.OOE+OO 8.93E-04 8.1SE-02 

4.00E+Ol 1.9SE-02 4.09E-02 O.OOE+OO 6. 38E-04 6.11E-02 

S.OOE+Ol 1.60E-02 2.96E-02 O.OOE+OO 4.56E-04 4.60E-02 

6.00E+OI 1.31E-02 2.14E-02 O.OOE+OO 3. 26E-04 3. 48E-02 

7.00E+Ol 1.07E-02 1.54E-02 O.OOE+OO 2.33E-04 2. 64E-02 

8.00E+OI 8.73E-03 1.12E-02 O.OOE+OO 1. 67E-04 2.00E-02 

9.00E+Ol 7.10E-OJ 8.05E-03 O.OOE+OO 1. 19E-04 1.53E-02 

1.OOE+02 5. 76E-03 S.82E-03 O.OOE+OO 8.51E-05 1. 17E-02 

2.00E+02 6. 52E-04 2. 23E-04 O.OOE+OO 2. 96E-06 8.79E-04 

3.00E+02 6.80E-05 8.50E-06 O.OOE+OO 1.03E-07 7. 66E-05 

4.00E+02 6. 85E-06 3.2IE-07 O.OOE+OO O.OOE+OO 7.17E-06 

5.00E+02 6.80E-07 1.20E-08 O.OOE+OO O.OOE+OO 6. 92E-07 

6.00E+02 6.7lE-08 O.OOE+OO O.OOE+OO O.OOE+OO 6.7lE-08 

B-236 
ClASS W AHAD == 1 KICRON BALFLIP'E= 3.52&+01 DAYS NIOBIUM 95 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 3.6IE-04 B.OBE-06 

2.00E-OI 7.7BE-04 1. 63E-04 

3.00E-OI I.I9E-03 B.22E-04 

4.00E-OI I.60E-03 2. 39E-03 

S.OOE-OI 2.00E-03 S.20E-03 

6.00E-OI 2.4IE-03 9. 46E-03 

7.00E-OI 2. BOE-03 1. S2E-02 

B.OOE-OI 3.20E-03 2.2SE-02 

9.00E-OI 3.S9E-03 3.12E-02 

I.OOE+OO 3. 97E-03 3. 97E-03 4.IIE-02 4.IIE-02 

2.00E+OO 3. 67E-03 7.S6E-03 I.29E-OI 1. 69E-OI 

3.00E+OO 3.27E-03 I.07E-02 I.07E-OI 2. 72E-OI 

4.00E+OO 2.90E-03 1. 34E-02 6.0BE-02 3.2BE-OI 

S.OOE+OO 2.SBE-03 I.S7E-02 3.06E-02 3.S2E-OI 

6.00E+OO 2. 29E-03 I.77E-02 1. SOE-02 3.60E-Ol 

7.00E+OO 2.04E-03 1. 94E-02 7.S6E-03 3.6IE-OI 

B.OOE+OO I.B2E-03 2.0BE-02 4.09E-03 3.SBE-OI 

9.00E+OO 1. 62E-03 2.20E-02 2. 46E-03 3.S3E-OI 

I.OOE+OI I.4SE-03 2.30E-02 I.6BE-03 3.4BE-OI 

2.00E+OI S.44E-04 2. 67E-02 7. 24E-04 2. 94E-OI 

3.00E+OI 2. 73E-04 2.S3E-02 S.I7E-04 2.47E-OI 

4.00E+Ol I.74E-04 2. 27E-02 3.70E-04 2.07E-OI 

S.OOE+OI 1.2SE-04 1. 99E-02 2.64E-04 1. 72E-Ol 

6.00E+Ol 9.4BE-OS 1. 73E-02 I.B9E-04 1. 44E-OI 

7.00E+Ol 7. 32E-OS I.SOE-02 I.3SE-04 I.I9E-0l 

B.OOE+OI S.6BE-OS 1. 29E-02 9.6SE-OS 9.90E-02 

9.00E+OI 4.42E-OS I.I0E-02 6.90E-OS B.20E-02 

1.00E+02 3. 44E-OS 9.4IE-03 4. 93E-oS 6. 79E-02 

2.00E+02 2. 93E-06 1.69E-03 1.72E-06 9.B2E-03 

3.00E+02 2.6SE--07 2. 67E-04 S.97E-OB 1.3BE-03 

4.00E+02 2.S0E-OB 4.03E-OS O.OOE+OO 1.92E-04 

", , . 

B-237 
CLASS W AMAD = 1 MICRON DALFLIPE= 1.53E+09 DAYS TECHNETIUM 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 8. 59E-02 2. 76E-01 2. 35E-01 3.96E-02 6. 36E-01 

2.00E-01 1.20E-01 2. 65E-01 1. 97E-01 4. 96E-02 6.32E-01 

3.00E-01 1.51E-01 2.56E-01 1. 66E-01 5.37E-02 6. 27E-01 

4.00E-01 1.76E-01 2.47E-01 1. 39E-01 5. 64E-02 6.20E-01 

5.00E-01 1.96E-01 2.40E-01 1. 17E-01 5.84E-02 6. 11E-01 

6.00E-01 2. 11E-01 2. 33E-01 9. 86E-02 5. 96E-02 6.02E-01 

7.00E-01 2.23E-01 2.27E-01 8. 29E-02 6.02E-02 5. 92E-01 

8.00E-01 2.31E-01 2.21E-01 6. 97E-02 6.02E-02 5. 82E-01 

9.00E-01 2. 37E-01 2. 16E-01 5. 86E-02 5.98E-02 5. 71E-01 

1.00E+00 2.40E-01 2. 11E-01 4. 93E-02 5. 89E-02 5. 59B-01 

2.00E+00 2.20E-01 1.77E-01 8. 72E-03 3.95E-02 4.45E-01 

3.00E+00 1. 74E-01 1.60E-01 l.54E-03 2. 12E-02 3. 57E-:-01 

4.00E+00 1.35E-01 1.50E-01 2.72E-04 1.06E-02 2. 96E-Ol 

5.00E+00 1.04E-01 1. 45E-01 4. 82E-05 5.30E-03 2. 54E-01 

6.00E+00 8.23E-02 1.41E-Ol 8.51E-06 2. 77E-03 2. 26E-Ol 

7.00E+00 6.61E-02 1. 38E-01 1. 51E-06 1.57E-03 2.06E-01 

8.00E+00 5. 43E-02 1. 36E-Ol 2. 66E-07 1.00E-03 1.91E-01 

9.00E+00 4. 56E-02 1. 34E-01 4.70E-08 7. 29E-04 1.80E-01 

1.00E+Ol 3.91E-02 1.32E-01 O.OOE+OO 5. 93E-04 1.72E-01 

2.00E+01 1. 74E-02 1. 16E-01 O.OOE+OO 4.09E-04 1. 34E-01 

3.00E+Ol 1. 25E-02 1.02E-01 O.OOE+OO 3. 56E-04 1. 15E-01 

4.00E+Ol 9. 85E-03 9.01E-02 O.OOE+OO 3.10E-04 1.00E-01 

5.00E+01 7.97E-03 7. 93E-02 O.OOE+OO 2.70E-04 8. 75E-02 

6.00E+01 6. 53E-03 6. 98E-02 O.OOE+OO 2. 35E-04 7. 65E-02 

7.00E+01 5.40E-03 6. 14E-02 O.OOE+OO 2.04E-04 6.70E-02 

8.00E+01 4.50E-03 5.40E-02 O.OOE+OO 1. 78E-04 5.. 87E-02 

9.00E+01 3. 77E-03 4. 75E-02 O.OOE+OO 1.55E-04 5. 14E-02 

1.00E+02 3. 19E-03 4. 18E-02 O.OOE+OO 1. 35E-04 4. 51E-02 

2.00E+02 7.39E-04 1. 15E-02 O.OOE+OO 3. 37E-05 1. 23E-02 

3.00E+02 2.00E-04 3. 15E-03 O.OOE+OO 8. 43E-06 3. 36E-03 

4.00E+02 5. 48E-05 8.55E-04 O.OOE+OO 2. 11E-06 9. 12E-04 

5.00E+02 1.50E-05 2. 31E-04 O.OOE+OO 5. 27E-07 2. 46E-04 

6.00E+02 4.08E-06 6. 19E-05 O.OOE+OO 1.32E-07 6. 61E-05 

7.00E+02 1.10E-06 1. 65E-05 O.OOE+OO 3. 29E-08 1.77E-05 

8.00E+02 2.96E-07 4.40E-06 O.OOE+OO O.OOE+OO 4. 69E-06 

9.00E+02 7.90E-08 1. 16E-06 O.OOE+OO O.OOE+OO 1.24E-06 

1.00E+03 2.1OE-08 3.08E-07 O.OOE+OO O.OOE+OO 3. 29E-07 

B-238 
CLASS V AHAD ... 1 MICRON IlALFLlFE= 1. 538+09 DAYS TECIlNBTIOH 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2. 63E-03 S.74E-06 

2.00E-Ol 6. 73E-03 9.0lE-05 

3.00E-0l 1.2lE-02 3.7BE-04 

4.00E-Ol 1. 86E-02 9.6lE-04 

5.00E-Ol 2. 59E-02 1. B8E-03 

6.00E-Ol 3.3BE-02 3.l5E-03 

7.00E-Ol 4. 22E-02 4. 75E-03 

8.00E-Ol 5.09E-02 6. 65E-03 

9.00E-Ol 5. 97E-02 S.82E-03 

1.00E+OO 6.8BE-02 6.SBE-02 1. 12E-02 1. 12E-02 

2.00E+OO 8.SBE-02 1.5SE-0l 2. BOE-02 3. 92E-02 

3.00E+OO 6.71E-02 2. 22E-Ol 2.l6E-02 6.08E-02 

4.Qt>E+OO 4.B9E-02 2.70E-OI 1.22E-02 7.30E-02 

5.00E+OO 3.5lE-02 3.06E-OI 6.l9E-03 7.9lE-02 

6.00E+OO 2.54E-02 3.3IE-Ol 3.lOE-03 B.22E-02 

7.00E+OO l.85E ..... 02 3.50E-Ol 1.60E-03 8.3BE-02 

8.00E+OO 1.37E-02 3. 63E-Ol 8.95E-04 8. 47E-02 

9.00E+OO l.04E-02 3. 74E-Ol 5. 59E-04 8. 53E-02 

1.00E+Ol 8.03E-03 3.B2E-OI 3.97E-04 8. 57E-02 

2.00E+Ol 2.llE-03 4.l7E-Ol 2.l7E-04 8.8lE-02 

3.00E+Ol 1. 47E-03 4. 34E-Ol 1.89E-04 9.02E-02 

4.00E+OI 1.22E-03 4. 47E-Ol 1. 64E-04 9.l9E-02 

5.00E+Ol I.OSE-03 4.5BE-OI 1. 43E-04 9. 34E-02 

6.00E+OI 9.0SE-04 4.6BE-Ol I. 24E-04 9. 48E-02 

7.00E+OI 7.B7E-04 4. 76E-OI 1.OBE-04 9. 59E-02 

8.00E+OI 6.B6E-04 4. 84E-OI 9. 43E-05 9. 69E-02 

9.00E+Ol S.99E-04 4.90E-0l 8.2IE-OS 9.7BE-02 

I.OOE+02 5. 23E-04 4.95E-OI 7.14E-OS 9. 85E-02 

2.00E+02 1. 43E-04 5.24E-OI I. 79E-05 I.02E-Ol 

3.00E+02 3. 95E-05 5. 32E-OI 4. 46E-06 1.03E-OI 

4.00E+02 I.09E-05 5. 35E-Ol 1.12E-06 1.04E-Ol 

5.00E+02 2. 97E-06 5. 35E-OI 2. 79E-07 I.04E-OI 

6.00E+02 B.07E-07 5.35E-OI 6.9BE-OB I.04E-OI 

7.00E+02 2.I8E-07 S.35E-OI 1. 74E-OB I.04E-OI 

, . '-~ 8.00E+02 5.B4E-OB S.35E-OI O.OOE+OO I.04E-Ol 

9.00E+02 1. 56E-08 5. 35E-OI O.OOE+OO 1.04E-Ol 

B-239 
CLASS W AMAD = 1 KICRON STABLE R.UTHENIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI . TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.92E-02 2.76E-Ol 2.3SE-Ol S.6BE-02 6. 37E-Ol 

2.00E-Ol 6.B6E-02 2. 65E-Ol 1.97E-Ol 1.04E-Ol 6.3SE-Ol 

3.00E-Ol 6.B6E-02 2.S6E-Ol 1.66E-Ol 1.42E-Ol 6.32E-Ol 

4.00E-Ol 6.9lE-02 2. 47E-Ol 1. 39E-Ol 1.73E-Ol 6. 29E-Ol 

S.OOE-Ol 6. 96E-02 2.40E-Ol 1.17E-Ol 1. 99E-Ol 6. 25E-Ol 

6.00E-Ol 7.0lE-02 2.33E-Ol 9.B6E-02 2.lBE-Ol 6.20E-Ol 

7.00E-Ol 7.06E-02 2.27E-Ol B.29E-02 2. 33E-Ol 6. 13E-Ol 

B.OOE-Ol 7.lOE-02 2.2lE-Ol 6. 97E-02 2.43E-Ol . 6.0SE-Ol 

9.00E-0l 7.l3E-02 2.l6E-Ol S.B6E-02 2. SOE-Ol 5. 95E-Ol 

1.OOE+OO 7.l6E-02 2.llE-Ol 4. 93E-02 2.S3E-Ol S.BSE-Ol 

2.00E+OO 7.l8E-02 1.77E-Ol B.72E-03 1.93E-Ol 4.SlE-Ol 

3.00E+OO 7.04E-02 1.60E-Ol 1.S4E-03 1.07E-Ol 3. 39E-Ol 

4.00E+OO 6.B7E-02 1. SOE-Ol 2.72E-04 S.40E-02 2. 73E-Ol 

S.OOE+OO 6.6BE-02 1.4SE-Ol 4.B2E-OS 2.69E-02 2.3BE-Ol 

6.00E+OO 6.S0E-02 1.4lE-Ol B.5lE-06 1.39E-02 2.20E-Ol 

7.00E+OO 6.33E-02 1.3BE-Ol 1.SlE-06 7.70E-03 2.09E-Ol 

B.OOE+OO 6.l7E-02 1.36E-0l 2. 66E-07 4.77E-03 2.02E-Ol 

9.00E+OO 6.02E-02 1.34E-Ol 4.70E-OB 3. 36E-03 1. 97E-Ol 

1.OOE+Ol 5.BBE-02 1.32E-Ol O.OOE+OO 2. 67E-03 1. 94E-Ol 

2.00E+Ol 4.9lE-02 1.16E-Ol O.OOE+OO 1.7BE-03 1. 67E-Ol 

3.00E+Ol 4.40E-02 1.02E-Ol O.OOE+OO 1.S5E-03 1.4BE-Ol 

4.00E+Ol 4.09E-02 9.0lE-02 O.OOE+OO 1. 35E-03 1.32E-Ol 

S.OOE+Ol 3.B9E-02 7. 93E-02 O.OOE+OO 1.17E-03 1.19E-Ol 

6.00E+Ol 3. 73E-02 6.9BE-02 O.OOE+OO 1.02E-03 1.OBE-Ol 

7.00E+Ol 3.60E-02 6.14E-02 O.OOE+OO B.90E-04 9.B3E-02 

B.OOE+Ol 3. 49E-02 5.40E-02 O.OOE+OO 7. 75E-04 B.97E-02 

9.00E+Ol 3. 39E-02 4.7SE-02 O.OOE+OO 6. 75E-04 B.2lE-02 

1.OOE+02 3.3lE-02 4.lBE-02 O.OOE+OO S.B7E-04 7/SSE-02 

2.00E+02 2.7BE-02 1.lSE-02 O.OOE+OO 1.47E-04 3. 94E-02 

3.00E+02 2. 49E-02 3.lSE-03 O.OOE+OO 3. 67E-OS 2. BlE-02 

4.00E+02 2. 29E-02 8.SSE-04 O.OOE+OO 9.lBE-06 2.3BE-02 

S.OOE+02 2.13E-02 2.3lE-04 O.OOE+OO 2. 29E-06 2.l5E-02 

6.00E+02 1. 99E-02 6.l9E-05 O.OOE+OO 5. 74E-07 1. 99E-02 

7.00E+02 1.BSE-02 1.6SE-05 O.OOE+OO 1. 43E-07 1.B5E-02 

B.OOE+02 1. 73E-02 4.40E-06 O.OOE+OO 3.5BE-OB 1. 73E-02 

I 

9.00E+02 1.6lE-02 1.16E-06 O.OOE+OO O.OOE+OO 1.6lE-02 

1.OOE+03 1.SOE-02 3.0BE-07 O.OOE+OO O.OOE+OO 1.SOE-02 

I 2.00E+03 7.S2E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.S2E-03 I 

I 

I 4.00E+03 ·1.BBE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.BBE-03 I· 

5.00E+03 9.40E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.40E-04 

7.00E+03 2.3SE-04 O.OOE+OO O.OOE+OO O.OOE+OO 2.3SE-04 

B.OOE+03 1.lBE-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.lBE-04 

1.00E+04 2. 94E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2. 94E-OS 

2.00E+04 2.BBE-OB O.OOE+OO O.OOE+OO O.OOE+OO 2.BBE-OB 

B-240 
CLASS W AMAD == 1 MICRON STABLE RDTHENIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-01 2.13E-03 8.06E-06 

2.00E-Ol 4. 23E-03 1. 62E-04 

3.00E-Ol 6.00E-03 B.17E-04 

4.00E-Ol 7. 52E-03 2.3BE-03 

5.00E-Ol 8. 85E-03 5.16E-03 

6.00E-Ol 1.OOE-02 9.3BE-03 

7.00E-Ol 1.11E-02 1.51E-02 

B.OOE-Ol 1.20E-02 2. 23E-02 

9.00E-0l 1.28E-02 3.09E-02 

1.OOE+OO 1. 36E-02 1. 36E-02 4.07E-02 4.07E-02 

2.00E+OO 5.16E-03 1. BBE-02 1.29E-Ol 1.70E-Ol 

3.00E+OO 3.41E-03 2.22E-02 1.OBE-Ol 2.7BE-Ol 

4.00E+OO 2.90E-03 2.51E-02 6.2BE-02 3.41E-Ol 

5.00E+OO 2. 65E-03 2.77E-02 3. 23E-02 3. 73E-Ol 

6.00E+OO 2.47E-03 3.02E-02 1.61E-02 3. B9E-0l 

7.00E+OO 2. 32E-03 3. 25E-02 8.29E-03 3.9BE-Ol· 

8.00E+OO 2.1BE-03 3.47E-02 4.57E-03 4.02E-Ol 

9.00E+OO 2.05E-03 3.6BE-02 2.BIE-03 4.05E-Ol 

1.OOE+Ol 1. 94E-03 3.B7E-02 1. 96E-03 4.07E-0l 

2.00E+Ol 1.19E-03 5.35E-02 1.03E-03 4.19E-Ol 

3.00E+Ol 8.30E-04 6. 32E-02 8. 97E-04 4.2BE-Ol 

4.00E+Ol 6. 45E-04 7.03E-02 7.81E-04 4.36E-Ol 

S.OOE+Ol S.35E-04 7. 62E-02 6. BOE-04 4.44E-Ol 

6.00E+Ol 4. 62E-04 B.llE-02 5.92E-04 4.S0E-Ol 

7.00E+Ol 4.06E-04 8.S4E-02 S.15E-04 4. 55E-Ol 

B.OOE+Ol 3.61E-04 B.92E-02 4.4BE-04 4.60E-Ol 

9.00E+Ol 3. 23E-04 9. 26E-02 3.90E-04 4.64E-Ol 

1.OOE+02 2. 89E-04 9.S6E-02 3.40E-04 4.6BE-Ol 

2.00E+02 1.03E-04 1.l3E-Ol B.50E-05 4.B6E-OI 

3.00E+02 4. 33E-OS 1.20E-Ol 2.12E-05 4.91E-Ol 

4.00E+02 2. 37E-OS 1.23E-Ol S.31E-06 4. 92E-Ol 

5.00E+02 1.7lE-OS 1.2SE-Ol 1.33E-06 4. 92E-Ol 

6.00E+02 1.44E-OS 1.27E-OI 3. 32E-07 4. 92E-Ol 

7.00E+02 1.30E-05 1.28E-Ol B.30E-OB 4. 92E-Ol 

B.OOE+02 1.20E-05 1.29E-OI 2.07E-OB 4.92E-Ol 

9.00E+02 1.12E-05 1.31E-Ol O.OOE+OO 4.92E-Ol 

1.OOE+03 1.04E-OS 1.32E-Ol O.OOE+OO 4. 92E-Ol 

2.00E+03 5.21E-06 1. 39E-Ol O.OOE+OO 4. 92E-Ol 

4.00E+03 1.30E-06 1.4SE-0l O.OOE+OO 4. 92E-OI 

B.OOE+03 B.15E-OB 1.47E-Ol O.OOE+OO 4. 92E-Ol 

1.OOE+04 2.04E-OB 1.47E-OI O.OOE+OO 4. 92E-Ol 

B-241 
CLASS W .AMAD - 1 MICRON STABLE RHODIUM 103 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 92E-02 2.76E-Ol 2.35E-Ol 5.68E-02 6.37E-Ol 

2.00E-Ol 6.S6E-02 2.65E-Ol 1. 97E-Ol 1.04E-Ol 6. 35E-Ol 

3.00E-OI 6.S6E-02 2. 56E-OI 1.66E-OI 1.42E-OI 6. 32E-OI 

4.00E-OI 6.9lE-02 2. 47E-OI 1. 39E-OI 1. 73E-OI 6.29E-Ol 

5.00E-OI 6 .. 96E-02 2.40E-OI 1.17E-Ol 1.99E-OI 6. 25E-Ol 

6.00E-Ol 7.0IE-02 2. 33E-Ol 9.S6E-02 2.ISE-OI 6.20E-Ol 

7.00E-Ol 7.06E-02 2.27E-Ol S.29E-02 2. 33E-Ol 6.13E-Ol 

B.OOE-Ol 7.l0E-02 2.2IE-Ol 6. 97E-02 2. 43E-Ol 6.05E-OI 

9.00E-OI 7.13E-02 2.16E-OI 5.S6E-02 2.50E-OI 5. 95E-Ol 

1.OOE+OO 7.16E-02 2.11E-OI 4. 93E-02 2. 53E-OI S.SSE-OI 

2.00E+OO 7.lSE-02 1.77E-Ol B.72E-03 1.93E-0l 4.SlE-OI 

3.00E+OO 7.04E-02 1.60E-Ol 1. 54E-03 1.07E-OI 3. 39E-Ol 

4.00E+OO 6. 87E-02 1. SOE-OI 2.72E-04 S.40E-02 2. 73E-OI 

5.00E+OO 6.6BE-02 1.4SE-OI 4.S2E-OS 2. 69E-02 2.3SE-OI 

6.00E+OO 6.50E-02 1.4lE-Ol S.5IE-06 1. 39E-02 2.20E-OI 

7.00E+OO 6. 33E-02 1. 38E-OI 1.51E-06 7.70E-03 2.09E-Ol 

8.00E+OO 6.17E-02 1.36E-0l 2. 66E-07 4.77E-03 2.02E-OI 

9.00E+OO 6.02E-02 1. 34E-OI 4.70E-OS 3. 36E-03 1.97E~OI 

1.OOE+Ol 5.8SE-02 1.32E-OI O.OOE+OO 2. 67E-03 1.94E-0l 

2.00E+Ol 4.9IE-02 1.16E-Ol O.OOE+OO 1. 78E-03 1. 67E-Ol 

3.00E+OI 4.40E-02 I.02E-Ol O.OOE+OO 1.55E-03 1.48E-OI 

4.00E+OI 4.09E-02 9.0lE-02 O.OOE+OO 1.3SE-03 1.32E-Ol 

S.OOE+OI 3.S9E-02 7.93E-02 O.OOE+OO 1.17E-03 1.19E-0l 

6.00E+OI 3. 73E-02 6. 98E-02 O.OOE+OO I.02E-03 1.OSE-Ol 

7.00E+Ol 3.60E-02 6.l4E-02 O.OOE+OO B.90E-04 9. 83E-02 

8.00E+OI 3. 49E-02 5 .. 40E-02 O.OOE+OO 7.7SE-04 8. 97E-02 

9.00E+OI 3. 39E-02 4.7SE-02 O.OOE+OO 6.75E-04 S.2lE-02 

I.OOE+02 3.3lE-02 4.18E-02 O.OOE+OO 5. 87E-04 7. 55E-02 

2.00E+02 2.7SE-02 1.ISE-02 O.OOE+OO 1. 47E-04 3. 94E-02 

3.00E+02 2.49E-02 3.ISE-03 O.OOE+OO 3. 67E-OS 2.SIE-02 

4.00E+02 2. 29E-02 8.SSE-04 O.OOE+OO 9.ISE-06 2.3SE-02 

S.OOE+02 2.13E-02 2.3IE-04 O.OOE+OO 2. 29E-06 2.ISE-02 

6.00E+02 1.99E-02 6.l9E-05 O.OOE+OO S.74E-07 1. 99E-02 

7.00E+02 1.SSE-02 1. 65E-OS O.OOE+OO 1. 43E-07 I.SSE-02 

8.00E+02 1. 73E-02 4.40E-06 O.OOE+OO 3. SSE-OS 1. 73E-02 

9.00E+02 1.6IE-02 1.16E-06 O.OOE+OO O.OOE+OO 1.6IE-02 

I.OOE+03 1. SOE-02 3.08E-07 O.OOE+OO O.OOE+OO 1. SOE-02 

2.00E+03 7.52E-03 O.OOE+OO O.OOE+OO O.OOE+OO 7.S2E-03 

4.00E+03 I.SSE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.8SE-03 

5.00E+03 9.40E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.40E-04 

7.00E+03 2.35E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2.3SE-04 

B.OOE+03 1.lBE-04 O.OOE+OO O.OOE+OO O.OOE+OO I.I8E-04 

1.OOE+04 2. 94E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2. 94E-OS 

2.00E+04 2.S8E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.SSE-OB 

B-242 
CLASS W MAD = 1 MICRON STABLE RHODIUM 10J 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.l3E-03 8.06E-06 

2.00E-Ol 4. 23E-03 I. 62E-04 

3.00E-0l 6.00E-03 8.l7E-04 

4.00E-OI 7. 52E-03 2. 38E-03 

5.00E-0l 8. 85E-03 5.16E-03 

6.00E-OI 1.OOE-02 9. 38E-03 

7.00E-Ol 1.llE-02 1. SIE-02 

8.00E-Ol 1.20E-02 2. 23E-02 

9.00E-OI 1.28E-02 3.09E-02 

1.OOE+OO 1.36E-02 1. 36E-02 4.07E-02 4.07E-02 

2.00E+OO S.16E-03 1. 88E-02 1.29E-OI 1.70E-Ol 

3.00E+OO 3.4lE-OJ 2. 22E-02 1.08E-Ol 2. 78E-OI 

4.00E+OO 2.90E-03 2.5lE-02 6.28E-02 3.4lE-Ol 

5.00E+OO 2.6SE-03 2.77E-02 3. 23E-02 3. 73E-OI 

6.00E+OO 2.47E-03· 3.02E-02 1.61E-02 3.89E-Ol 

7.00E+OO 2. 32E-03 3. 25E-02 8.29E-03 3. 98E-ol 

8.00E+OO 2.18E-OJ 3. 47E-02 4. 57E-03 4.02E-Ol 

9.00E+OO 2.05E-03 3. 68E-02 2.8lE-03 4.05E-Ol 

1.OOE+OI 1. 94E-03 3. 87E-02 I. 96E-03 4.07E-Ol 

2.00E+Ol 1.19E-03 S.35E-02 I.03E-OJ 4.l9E-Ol 

3.00E+Ol 8.30E-04 6. 32E-02 B.97E-04 4.2BE-OI 

4.00E+OI 6. 45E-04 7.03E-02 7.8IE-04 4. 36E-OI 

S.OOE+OI S.3SE-04 7. 62E-02 6.80E-04 4. 44E-OI 

6.00E+Ol 4. 62E-04 B.llE-02 S.92E-04 4.S0E-OI 

7.00E+Ol 4.06E-04 B.S4E-02 S.ISE-04 4. SSE-Ol 

8.00E+OI 3.6IE-04 B.92E-02 4. 48E-04 4.60E-Ol 

9.00E+OI 3. 23E-04 9. 26E-02 3.90E-04 4. 64E-OI 

1.OOE+02 2.B9E-04 9.S6E-02 3.40E-04 4.6BE-Ol 

2.00E+02 1.03E-04 1.13E-Ol B.SOE-OS 4. 86E-OI 

3.00E+02 4. 33E-OS 1.20E-Ol 2.12E-OS 4.9lE-Ol 

4.00E+02 2.37E-OS 1. 23E-Ol S.3lE-06 4.92E-OI 

S.OOE+02 1.7lE-OS 1.2SE-OI 1. 33E-06 4. 92E-Ol 

6.00E+02 1. 44E-OS 1.27E-0l 3. 32E-07 4.92E-Ol 

7.00E+02 1.30E-OS I. 28E-Ol 8.30E-08 4. 92E-Ol 

8.00E+02 1.20E-OS 1.29E-OI 2.07E-08 4.92E-0l 

9.00E+02 1.12E-OS 1.3IE-Ol O.OOE+OO 4. 92E-Ol 

I.OOE+03 1.04E-OS 1.32E-Ol O.OOE+OO 4.92E-Ol 

2.00E+03 S.2lE-06 1. 39E-Ol O.OOE+OO 4. 92E-Ol 

4.00E+03 1.30E-06 1.4SE-OI O.OOE+OO 4. 92E-Ol 

8.00E+03 8.lSE-OB 1.47E-Ol O.OOE+OO 4. 92E-Ol 

1.OOE+04 2.04E-OB 1.47E-Ol O.OOE+OO 4.92E-OI 

B-243 
CLASS W AHA» = 1 MICR.ON STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS· LUNGS PASSAGES TRACT BODY 

1.00E-01 6 .. 63E-02 2. 76E-01 2.35E-0l 5. 71E-02 6. 34E-01 

2.00E-01 6. 23E-02 2. 65E-01 1.97E-OI I.05E-Ol 6.30E-OI 

3.00E-OI 5. 92E-02 2.56E-01 l.66E-OI 1 .. 45E-OI 6.26E-OI 

4.00E-OI 5.6SE-02 2.47E-01 1. 39E-OI 1.7SE-OI 6. 22E-OI 

5.00E-OI 5.50E-02 2.40E-OI 1.17E-OI 2.05E-OI 6.17E-01 

6.00E-OI 5.36E-02 2. 33E-OI 9.S6E-02 2. 26E-01 6.llE-OI 

7.00E-OI 5.25E-02 2.27E-01 S.29E-02 2.42E-OI 6.04E-01 

8.00E-OI 5. 16E-02 2.2IE-01 6. 97E-02 2. 53E-01 S.9SE-01 

9.00E-OI 5.09E-02 2.16E-OI 5. 86E-02 2.60E-OI 5. 86E-01 

1.00E+OO 5.03E-02 2.IIE-01 4. 93E-02 2. 64E-OI S.7SE-OI 

2.00E+OO 4. 74E-02 I.77E-01 8.72E-03 2.02E-Ol 4. 36E-OI 

3.00E+OO 4. 56E-02 I.60E-OI I.54E-03 1. 13E-OI 3.20E-01 

4.00E+OO 4.40E-02 I.SOE-01 2.72E-04 5. 69E-02 2.SIE-OI 

5.00E+OO 4. 23E-02 1. 45E-01 4.S2E-05 2. 83E-02 2.15E-OI 

6.00E+OO 4.0SE-02 I.41E-0l 8.SIE-06 1. 46E-02 1.96E-01 

7.00E+OO 3. 93E-02 1. 38E-OI 1.SIE-06 8.09E-03 1.8SE-OI 

8.00E+OO 3.78E-02 1.36E-Ol 2.66E-07 S.OlE-03 1. 79E-OI 

9.00E+OO 3.6SE-02 1.34E-01 4.70E-08 3.S3E-03 1. 74E-01 

I.OOE+Ol 3.S2E-02 I.32E-Ol O.OOE+OO 2.S0E-03 I.70E-0l 

2.00E+01 2.47E-02 I.16E-Ol O.OOE+OO 1. 86E-03 1. 43E-OI 

3.00E+01 1.79E-02 1.02E-Ol O.OOE+OO 1. 62E-03 1. 22E-OI 

4.00E+OI 1. 34E-02 9.0IE-02 O.OOE+OO 1.4IE-03 1. 

5.00E+OI I.03E-02 7.93E-02 O.OOE+OO 1.23E-03 9.08E 

6.00E+OI 8. 23E-03 6. 98E-02 O.OOE+OO 1.07E-03 7.9IE-02 

7.00E+Ol 6.74E-03 6.I4E-02 O.OOE+OO 9.3IE-04 6.90E-02 

8.00E+Ol 5. 64E-03 5.40E-02 O.OOE+OO S.IIE-04 6.0SE-02 

9.00E+01 4. 82E-03 4. 75E-02 O.OOE+OO 7.06E-04 5.30E-02 

1.00E+02 4.17E-03 4.18E-02 O.OOE+OO 6.1SE-04 4. 66E-02 

2.00E+02 1. 27E-03 1.lSE-02 O.OOE+OO 1. S4E-04 1. 29E-02 

3.00E+02 3.9SE-04 3.15E-03 O.OOE+OO 3.S4E-OS 3. 59E-03 

4.00E+02 1.20E-04 8.55E-04 O.OOE+OO 9.60E-06 9.85E-04 

S.OOE+02 3.50E-OS 2.3IE-04 O.OOE+OO 2.40E-06 2.6SE-04 

6.00E+02 1.OOE-05 6.19E-05 O.OOE+OO 6.00E-07 7.25E-05 

7.00E+02 2.S2E-06 1. 65E-OS O.OOE+OO 1.SOE-07 1. 95E-OS 

S.OOE+02 7. 86E-07 4.40E-06 O.OOE+OO 3.75E-OS 5. 22E-06 

9.00E+02 2.16E-07 I.16E-06 O.OOE+OO O.OOE+OO I.3SE-06 .... 1.OOE+03 5.90E-OS 3.0SE-07 O.OOE+OO O.OOE+OO 3.67E-07 

B-244 
CLASS W AMAD = 1 MICRON STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.6BE-03 B.lOE-06 

2.00E-Ol B.99E-03 1. 64E-04 

3.00E-Ol 1.23E-02 B.2BE-04 

4.00E-Ol 1. 49E-02 2. 42E-03 

5.00E-Ol 1.70E-02 5. 27E-03 

6.00E-Ol 1.B6E-02 9. 59E-03 

7.00E-Ol l.99E-02 1.55E-02 

B.OOE-Ol 2.09E-02 2. 29E-02 

9.00E-Ol 2.lBE-02 3.lBE-02 

l.OOE+OO 2. 25E-02 2. 25E-02 4.20E-02 4.20E-02 

2.00E+OO 3.9lE-03 2. 64E-02 1.35E-Ol 1.77E-Ol 

3.00E+OO 2.45E-03 2.B9E-02 1.14E-Ol 2.90E-Ol 

4.00E+OO 2.25E-03 3.l1E-02 6.6lE-02 3.57E-Ol 

5.00E+OO 2.l5E-03 3. 33E-02 3.40E-02 3.9lE-Ol 

6.00E+OO 2.07E-03 3.54E-02 1.70E-02 4.0BE-Ol 

7.00E+OO 2.00E-03 3. 74E-02 B.73E-03 4.l6E-Ol 

B.OOE+OO 1. 93E-03 3. 93E-02 4.BlE-03 4.2lE-Ol 

9.00E+OO 1.B6E-03 4.l2E-02 2. 95E-03 4. 24E-Ol 

1.OOE+Ol 1.80E-03 4. 29E-02 2.06E-03 4. 26E-Ol 

2.00E+Ol 1.29E-03 5.80E-02 1.08E-03 4.3BE-Ol 

3.00E+Ol 9. 56E-04 6.B9E-02 9.40E-04 4.4BE-Ol 

4.00E+OI 7. 33E-04 7. 72E-02 B.lBE-04 4. 57E-Ol 

5.00E+Ol 5. 79E-04 8. 36E-02 7.12E-04 4. 65E-Ol 

6.00E+Ol 4.71E-04 B.8BE-02 6.20E-04 4.71E-OI 

7.00E+Ol 3. 92E-04 9.30E-02 5.40E-04 4.77E-OI 

8.00E+Ol 3. 33E-04 9. 66E-02 4.70E-04 4.B2E-Ol 

9.00E+Ol 2.B7E-04 9. 97E-02 4.09E-04 4.B6E-Ol 

1.00E+02 2.5IE-04 1.02E-Ol 3. 56E-04 4.90E-OI 

2.00E+02 7.76E-05 1.17E-OI B.90E-05 5.09E-Ol 

3.00E+02 2. 43E-05 1.2IE-Ol 2.23E-05 5.14E-OI 

4.00E+02 7.29E-06 1.23E-Ol 5. 56E-06 5.l5E-Ol 

5.00E+02 2.l3E-06 1. 23E-Ol 1.39E-06 5. 16E-OI 

6.00E+02 6.09E-07 1.23E-Ol 3. 48E-07 5.l6E-Ol 

7.00E+02 1. 71E-07 1.23E-Ol B.69E-08 5.l6E-Ol . ~ . .' B.OOE+02 4. 76E-OB 1.23E-Ol 2.l7E-OB 5.l6E-Ol 

9.00E+02 1.3lE-08 1.23E-OI O.OOE+OO 5.l6E-Ol 

B-245 
CLASS W MAD = 1 MICRON STABLE SILVER 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l2E-02 2.76E-Ol 2.3SE-Ol S.6BE-02 6.39E-Ol 

2.00E-Ol 7. 24E-02 2.6SE-Ol 1. 97E-Ol 1.04E-Ol 6. 39E-Ol 

3.00E-Ol 7.40E-02 2. 56E-Ql 1.66E-Ol 1.42E-Ol 6.3BE-Ol 

4.00E-Ol 7.S7E-02 2. 47E-Ol 1.39E-OI 1. 73E-Ol 6. 36E-Ol 

S.OOE-Ol 7. 73E-02 2.40E-Ol 1. 17E-0l 1.99E-Ol 6. 33E-Ol 

6.00E-Ol 7. 88E-02 2. 33E-Ol 9.B6E-02 2.lBE-Ol 6. 28E-Ol 

7.00E-Ol B.OOE-02 2.27E-Ol B.29E-02 2.33E-Ol 6. 22E-Ol 

B.OOE-Ol B.llE-02 2.2lE-OI 6. 97E-02 2.43E-Ol 6.lSE-Ol 

9.00E-Ol B.2lE-02 2.l6E-OI S.B6E-02 2. SOE-Ol 6.06E-Ol 

1.00E+OO B.2BE-02 2.UE-Ol 4. 93E-02 2.S3E-Ol S.96E-Ol 

2.00E+OO B.5BE-02 1.77E-Ol B.72E-03 1. 93E-Ol 4.65E-Ol 

3.00E+OO B.S6E-02 1.60E-Ol 1.54E-03 1.07E-OI 3. 54E-Ol 

4.00E+OO B.46E-02 1. SOE-Ol 2. 72E-04 5.40E-02 2.B9E-Ol 

S.OOE+OO B.3SE-02 1. 45E-Ol 4.B2E-OS 2. 69E-02 2.S5E-Ol 

6.00E+OO B.24E-02 1.41E-0l B.SlE-06 1. 39E-02 2.37E-Ol 

7.00E+OO B.13E-02 1.3BE-OI I.SlE-06 7.70E-03 2. 27E-Ol 

B.OOE+OO B.03E-02 1.36E-Ol 2. 66E-07 4.77E-03 2.2lE-Ol 

9.00E+OO 7. 94E-02 1. 34E-Ol 4.70E-OB 3. 36E-03 2.l7E-Ol 

1.OOE+Ol 7.BSE-02 1.32E-Ol O.OOE+OO 2.67E-03 2.l3E-Ol 

2.00E+Ol 7. 17E-02 1.16E-0l O.OOE+OO 1.7BE-03 1.90E-OI 

3.00E+Ol 6.6lE-02 1.02E-0l O.OOE+OO 1. SSE-03 1. iOE-Ol 

4.00E+Ol 6.lOE-02 9.01E-02 O.OOE+OO 1.3SE-03 1.S2E-O 

S.OOE+Ol S.63E-02 7.93E-02 O.OOE+OO l.l7E-03 1.37E-O 

6.00E+Ol S.lBE-02 6.9BE-02 O.OOE+OO 1.02E-03 1. 23E-Ol 

7.00E+0l 4. 76E-02 6.l4E-02 O.OOE+OO B.90E-04 1.lOE-Ol 

B.OOE+Ol 4.3BE-02 S.40E-02 O.OOE+OO 7.7SE-04 9.BSE-02 

9.00E+Ol 4.0lE-02 4.7SE-02 O.OOE+OO 6.7SE-04 B.B3E-02 

1.OOE+02 3.6BE-02 4.lBE-02 O.OOE+OO S.B7E-04 7. 92E-02 

2.00E+02 1.4SE-02 l.lSE-02 O.OOE+OO 1.47E-04 2. 62E-02 

3.00E+02 S.30E-03 3.l5E-03 O.OOE+OO 3. 67E-OS B.49E-03 

4.00E+02 I.B3E-03 B. SSE-04 O.OOE+OO 9.1BE-06 2. 69E-03 

S.OOE+02 6.04E-04 2.31E-04 O.OOE+OO 2. 29E-06 B.37E-04 

6.00E+02 1. 93E-04 6.l9E-OS O.OOE+OO S.74E-07 2.SSE-04 

.7.00E+02 6.00E-OS 1.6SE-OS O.OOE+OO 1. 43E-07 7. 67E-OS 

B.OOE+02 1.B3E-OS 4.40E-06 O.OOE+OO 3. SBE-OS 2. 27E-OS 

9.00E+02 5. 47E-06 l.l6E-06 O.OOE+OO O.OOE+OO 6. 64E-06 

1.OOE+03 1.6lE-06 3.0BE-07 O.OOE+OO O.OOE+OO 1. 92E-06 

B-246 
CLASS W AHAD == 1 MICRON STABLE SILVER. 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1. 95E-04 8.06E-06 

2.00E-Ol 4. 24E-04 1. 62E-04 

3.00E-Ol 6. 55E-04 8.l7E-04 

4.00E-Ol 8.90E-04 2. 38E-03 

5.00E-Ol 1.l3E-03 5.l6E-03 

6.00E-Ol 1.37E-03 9.38E-03 

7.00E-Ol 1.6lE-03 1.5lE-02 

8.00E-Ol 1. 85E-03 2. 23E-02 

9.00E-Ol 2.lOE-03 3.09E-02 

1.00E+00 2. 35E-03 2. 35E-03 4.07E-02 4.07E-02 

2.00E+00 2. 42E-03 4. 77E-03 1. 29E-0l 1.70E-01 

3.00E+00 2. 27E-03 7.03E-03 1.08E-01 2.7SE-Ol 

4.00E+00 2.09E-03 9.12E-03 6. 28E-02 3.4lE-01 

5.00E+OO 1. 93E-03 1. IOE-02 3. 23E-02 3. 73E-Ol 

6.0~~00 1.79E-03 I.2SE-02 1.6lE-02 3. 89E-Ol 

7.00 +00 1. 67E-03 1.45E-02 S.29E-03 3.9SE-OI 

8.00E+00 I.57E-03 I.6IE-02 4.57E-03 4.02E-Ol 

9.00E+00 1.48E-03 1. 75E-02 2.SlE-03 4.05E-Ol 

1.00E+Ol I.4lE-03 I.90E-02 1.96E-03 4.07E-Ol 

2.00E+OI I.OSE-03 3.09E-02 I.03E-03 4.19E-OI 

3.00E+Ol 9. 68E-04 4. IOE-02 8. 97E-04 4.2SE-OI 

4.00E+OI S.89E-04 5.02E-02 7.SIE-04 4.36E-Ol 

5.00E+0l 8.18E-04 5.S7E-02 6.80E-04 4.44E-OI 

6.00E+OI 7. 52E-04 6. 66E-02 5. 92E-04 4.50E-Ol 

7.00E+OI 6.9IE-04 7. 37E-02 5.15E-04 4. 55E-OI 

S.OOE+OI 6. 34E-04 8.03E-02 4.4SE-04 4.60E-OI 

9.00E+Ol 5.S2E-04 S.64E-02 3.90E-04 4. 64E-OI 

1.00E+02 5. 33E-04 9.19E-02 3.40E-04 4. 68E-Ol 

2.00E+02 2.09E-04 1. 27E-OI 8.50E-05 4.S6E-Ol 

3.00E+.02 7. 59E-05 l.40E-01 2.l2E-05 4.91E-01 

4.00E+02 2.6IE-05 1. 44E-0l 5.31E-06 4. 92E-OI 

5.00E+02 8. 59E-06 I.46E-Ol 1. 33E-06 4. 92E-Ol 

6.00E+02 2. 74E-06 1.47E-OI 3.32E-07 4.92E-Ol 

7.00E+02 8.51E-07 1.47E-01 8.30E-OS 4. 92E-Ol 

S.OOE+02 2. 59E-07 1.47E-01 2.07E-08 4. 92E-OI 

9.00E+02 7. 74E-08 1.47E-OI O.OOE+OO 4. 92E-Ol 

1.00E+03 2.2SE-OS l.47E-01 O.OOE+OO 4.92E-OI 

B-247 
CLASS W AMAD == 1 MICRON STABLE CADMIUM: 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 7.l4E-02 2. 76E-Ol 2.35E-Ol 5.68E-02 6.39E-Ol 

2.00E-Ol 7. 28E-02 2. 65E-OI I. 97E-Ol 1.04E-OI 6.39E-OI 

3.00E-Ol 7.46E-02 2.56E-OI 1.66E-Ol 1.42E-OI 6. 38E-Ol 

4.00E-Ol 7. 66E-02 .-- 2.47E-OI 1.39E-Ol 1. 73E-OI 6.37E-Ol 

5.00E-Ol 7.84E-02 .. 2.40E-OI 1.17E-OI 1.99E-OI 6. 34E-Ol 

6.00E-Ol 8.0lE-02 2. 33E-Ol 9.86E-02 2.l8E-OI 6.30E-Ol 

7.00E-Ol 8.17E-02 2.27E-OI 8. 29E-02 2. 33E-Ol 6.24E-Ol 

8.00E-Ol 8.30E-02 i.2lE-Ol 6. 97E-02 2.43E-Ol 6.l7E-Ol 

9.00E-Ol 8.4lE-02 2.l6E-Ol 5.86E-02 2.50E-Ol 6.08E-Ol 

1.OOE+OO 8. 52E-02 2.11E-Ol 4. 93E-02 2. 53E-OI 5. 98E-Ol 

2.00E+OO 9.06E-02 1.77E-OI 8. 72E-03 1.93E-Ol 4.69E-Ol 

3.00E+OO 9. 26E-02 1.60E-OI 1. 54E-03 1.07E-Ol 3.6lE-OI 

4.00E+OO 9. 37E-02 1.50E-OI 2.72E-04 5.40E-02 2. 98E-Ol 

5.00E+OO 9. 45E-02 1.45E-OI 4. 82E-05 2. 69E-02 2. 66E-Ol 

6.00E+OO 9.52E-02 1.4IE-OI 8.5lE-06 1. 39E-02 2.50E-0l 

7.00E+OO 9. 58E-02 I. 38E-Ol 1.5lE-06 7.70E-03 2.42E-Ol 

8.00E+OO 9. 63E-02 1. 36E-Ol 2.66E-07 4.77E-03 2.37E-Ol 

9.00E+OO 9. 69E-02 I. 34E-Ol 4.70E-08 3. 36E-03 2. 34E-Ol 

1.OOE+Ol 9. 74E-02 1.32E-Ol O.OOE+OO 2.67E-03 2.32E-Ol 

2.00E+Ol 1.02E-Ol I.16E-Ol O.OOE+OO I. 78E-03 2.20E-OI 

3.00E+Ol 1.07E-OI 1.02E-0l O.OOE+OO 1.55E-03 2. lIE 

4.00E+Ol 1.IlE-Ol 9.0lE-02 O.OOE+OO 1. 35E-03 2. 

5.00E+Ol 1.15E-Ol 7. 93E-02 O.OOE+OO 1.17E-03 1.95E 

6.00E+Ol 1.18E-Ol 6. 98E-02 O.OOE+OO 1.02E-03 I. 89E-Ol 

7.00E+Ol 1.2lE-Ol 6.l4E-02 O.OOE+OO 8.90E-04 1.83E-Ol 

8.00E+Ol 1.23E-Ol S.40E-02 O.OOE+OO 7.7SE-04 1. 78E-Ol 

9.00E+Ol 1.26E-Ol 4.75E-02 O.OOE+OO 6.7SE-04 t74E-Ol 

I.OOE+02 1. 28E-Ol 4.18E-02 O.OOE+OO S.87E-04 .70E-OI 

2.00E+02 1. 39E-Ol 1.lSE-02 O.OOE+OO 1.47E-04 1.5lE-Ol 

3.00E+02 1. 42E-Ol 3.lSE-03 O.OOE+OO 3. 67E-OS 1.45E-Ol 

4.00E+02 1. 42E-0l 8.5SE-04 O.OOE+OO 9.18E-06 1.43E-Ol 

S.OOE+02 1.4lE-Ol 2.3lE-04 O.OOE+OO 2. 29E-06 1.42E-Ol 

6.00E+02 1.4lE-Ol 6.l9E-OS O.OOE+OO 5.74E-07 1.4lE-Ol 

7.00E+02 1.39E-Ol 1.6SE-OS O.OOE+OO 1.43E-07 1.40E-Ol 

8.00E+02 1.38E-0l 4.40E-06 O.OOE+OO 3. S8E-08 1.38E-Ol 

9.00E+02 1.37E-OI 1.16E-06 O.OOE+OO O.OOE+OO 1.37E-Ol 

1.OOE+03 1. 36E-Ol 3.08E-07 O.OOE+OO O.OOE+OO 1.36E-OI 

2.00E+03 1. 26E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1. 26E-OI 

4.00E+03 I.09E-Ol O.OOE+OO O.OOE+OO O.OOE+OO I.09E-OI 

5.00E+03 1.OIE-Ol O.OOE+OO O.OOE+OO O.OOE+OO I.OIE-Ol 

7.00E+03 8. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 64E-02 

8.00E+03 8.01E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.0lE-02 

1.OOE+04 6. 88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 88E-02 

2.00E+04 3. 22E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 22E-02 

B-248 
CLASS W AMAD == 1 MICRON STABLE CADMIUM. 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4. 63E-07 B.06E-06 

2.00E-Ol 1.OlE-06 1. 62E-04 

3.00E-Ol 1.S7E-06 B.17E-04 

4.00E-Ol 2.l4E-06 2.3BE-03 

5.00E-Ol 2. 73E-06 S.16E-03 

6.00E-Ol 3.33E-06 9.3BE-03 

7.00E-Ol 3.9SE-06 1.slE-02 

B.OOE-Ol 4. 57E-06 2. 23E-02 

9.00E-Ol s.2lE-06 3.09E-02 

1.OOE+OO s.BSE-06 S.BSE-06 4.07E-02 4.07E-02 

2.00E+OO 6.71E-06 1.26E-OS 1.29E-0l 1.70E-0l 

3.00E+OO 6.97E-06 1. 95E-OS 1.OBE-Ol 2.7BE-Ol 

4.00E+OO 7.0BE-06 2. 66E-05 6.2BE-02 3.4lE-Ol 

S.OOE+OO 7.lSE-06 3.3BE-Os 3. 23E-02 3. 73E-Ol 

6.00E+OO 7.20E-06 4.l0E-OS 1.6lE-02 3.B9E-Ol 

7.00E+OO 7.2SE-06 4.B2E-OS 8. 29E-03 3. 98E-Ol 

B.OOE+OO 7.30E-06 S.55E-05 4. 57E-03 4.02E-0l 

9.00E+OO 7. 34E-06 6.28E-05 2. BlE-03 4.05E-Ol 

1.OOE+Ol 7.38E-06 7.02E-05 1. 96E-03 4.07E-Ol 

2.00E+Ol 7. 76E-06 1. 46E-04 1.03E-03 4.l9E-Ol 

3.00E+Ol 8.lOE-06 2.26E-04 B.97E-04 4.28E-Ol 

4.00E+Ol 8.4lE-06 3.0BE-04 7.8lE-04 4.36E-Ol 

5.00E+Ol 8. 69E-06 3. 94E-04 6. BOE-04 4.44E-Ol 

6.00E+Ol 8. 94E-06 4.B2E-04 s.92E-04 4.s0E-Ol 

7.00E+Ol 9.l6E-06 S.73E-04 s.lsE-04 4.SSE-0l 

8.00E+Ol 9. 36E-06 6. 66E-04 4.4BE-04 4.60E-Ol 

9.00E+Ol 9. 54E-06 7.60E-04 3.90E-04 4. 64E-Ol 

1.OOE+02 9.70E-06 B.S7E-04 3.40E-04 4.6BE-OI 

2.00E+02 1.06E-OS 1.BBE-03 8.s0E-05 4.B6E-Ol 

3.00E+02 1.OBE-OS 2. 95E-03 2.l2E-Os 4.9lE-Ol 

4.00E+02 1.OBE-05 4.03E-03 S.3lE-06 4. 92E-Ol 

S.OOE+02 1.07E-Os s.llE-03 1. 33E-06 4. 92E-Ol 

6.00E+02 1.07E-OS 6.IBE-03 3. 32E-07 4. 92E-Ol 

7.00E+02 1.06E-05 7. 24E-03 8.30E-OB 4. 92E-Ol .. . . , .. B.OOE+02 1.05E-OS B.30E-03 2.07E-OB 4. 92E-Ol . , 

9.00E+02 1.04E-OS 9.3SE-03 O.OOE+OO 4. 92E-Ol 

1.OOE+03 1.04E-OS 1.04E-02 O.OOE+OO 4. 92E-Ol 

2.00E+03 9.60E-06 2.04E-02 O.OOE+OO 4. 92E-Ol 

4.00E+03 8.2sE-06 3. 82E-02 O.OOE+OO 4. 92E-Ol 

B.OOE+03 6.09E-06 6. 66E-02 O.OOE+OO 4. 92E-Ol 

1.OOE+04 s.23E-06 7. 79E-02 O.OOE+OO 4. 92E-Ol 

B-249 
CLASS W AMAD = I MICRON BALFLIFE= I.S6E+IS DAYS INDIUM 115 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 7.llE-02 2.76E-Ol 2. 35E-0l 5.70E-02 6.39E-Ol 

2.00E-Ol 7.lSE-02 2. 65E-Ol 1. 97E-Ol 1.05E-01 6. 39E-Ol 

3.00E-Ol 7. 25E-02 2. 56E-Ol 1.66E-Ol 1. 44E-0l 6.3SE-Ol 

4.00E-Ol 7.33E-02 2.47E-Ol 1. 39E-Ol 1. 77E-Ol 6.37E-Ol 

5.00E-Ol 7.4lE-02 2.40E-Ol 1.17E-0l 2.03E-Ol 6.34E-Ol 

6.00E-Ol 7.4SE-02 2. 33E-Ol 9. 86E-02 2.23E-Ol 6.30E-Ol 

7.00E-Ol 7. 54E-02 2.27E-Ol S.29E-02 2.39E-Ol 6.24E-Ol 

8.00E-Ol 7.60E-02 2.2lE-01 6. 97E-02 2.50E-Ol 6.l6E-01 

9.00E-Ol 7.65E-02 2.l6E-01 5. 86E-02 2.57E-Ol 6.08E-Ol 

1.00E+00 7.70E-02 2.llE-Ol 4. 93E-02 2.6lE-01 5.9SE-Ol 

2.00E+00 7.95E-02 1.77E-01 8. 72E-03 1. 99E-Ol 4.65E-Ol 

3.00E+00 8.06E-02 1.60E-01 1. 54E-03 1.llE-01 3. 53E-Ol 

4.00E+00 8.l3E-02 1.50E-01 2.72E-04 5.60E-02 2.SSE-Ol 

5.00E+00 8.l9E-02 1.45E-01 4.S2E-05 2. 78E-02 2. 54E-Ol 

6.00E+00 S.25E-02 1.4lE-Ol S.5lE-06 1.43E-02 2.3SE-Ol 

7.00E+00 S.30E-02 1.3SE-01 1.5lE-06 7. 96E-03 2.29F-Ol 

S.OOE+OO S.36E-02 1.36E-01 2. 66E-07 4.93E-03 2. 24E-Ol 

9.00E+00 S.4IE-02 1. 34E-Ol 4.70E-OS 3.47E-03 2.2lE-01 

1.00E+Ol S.46E-02 1.32E-OI O.OOE+OO 2.76E-03 2.l9E-01 

2.00E+Ol S.93E-02 1.16E-OI O.OOE+OO 1.S4E-03 2.07E-Ol 

3.00E+Ol 9. 36E-02 I.02E-Ol O.OOE+OO 1.60E-03 1.97E-01 

4.00E+OI 9. 75E-02 9.0lE-02 O.OOE+OO 1. 39E-03 1. S9E-0 

5.00E+Ol 1.OIE-01 7.93E-02 O.OOE+OO 1.2lE-03 1.BlE-Ol 

6.00E+OI 1.04E-01 6. 98E-02 O.OOE+OQ 1.05E-03 1.7SE-01 

7.00E+Ol 1.07E-01 6.l4E-02 O.OOE+OO 9.lSE-04 1. 69E-OI 

B.OOE+Ol 1.lOE-01 S.40E-02 O.OOE+OO 7. 99E-04 1. 64E-Ol 

9.00E+Ol 1.I2E-0l 4. 75E-02 0.00£+00 6.96E-04 1.60E-OI 

I.00E+02 I.I4E-OI 4.IBE-02 O.OOE+OO 6.05E-04 1.S6E-OI 

2.00E+02 I.26E-Ol 1.lSE-02 O.OOE+OO I.5IE-04 I.37E-Ol 

3.00E+02 I.jOE-Ol 3. ISE-03 O.OOE+OO 3.7BE-05 1. 33E-OI 

4.00E+02 I.3IE-0l B.55E-04 . O.OOE+OO 9. 46E-06 1. 32E-OI 

5.00E+02 1.3lE-01 2.3lE-04 O.OOE+OO 2. 37E-06 I.3IE-OI 

6.00E+02 I.3lE-OI 6.19E-OS O.OOE+OO 5.9IE-07 1.3IE-OI 

7.00E+02 I.3lE-OI I.6SE-05 O.OOE+OO I.4BE-07 I.3lE-01 

B.00E+02 I.3IE-OI 4.40E-06 O.OOE+OO 3.70E-OB I.3IE-OI 

9.00E+02 I.3lE-01 I.I6E-06 O.OOE+OO O.OOE+OO I.3IE-OI 

I.00E+03 I.3lE-OI 3.0SE-07 O.OOE+OO O.OOE+OO I.3IE-OI 

2.00E+03 I.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.3IE-OI 

4.00E+03 I.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.3IE-OI 

5.00E+03 I.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO I.3IE-OI 

7.00E+03 I.3IE-0l O.OOE+OO O.OOE+OO O.OOE+OO I.3IE-0l 

B.00E+03 I.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.31E-OI 

I.00E+04 1.31E-Ol O.OOE+OO O.OOE+OO O.OOE+OO I.3IE-Ol 

2.00E+04 I.3IE-OI O.OOE+OO O.OOE+OO O.OOE+OO 1. 31E-OI 

B-250 
CLASS W AMAD == 1 MICRON STABLE TIN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.35E-02 2. 76E-01 2. 35E-01 5.70E-02 6. 32E-Ol 

2.00E-Ol S.72E-02 2. 65E-01 1.97E-01 1.0SE-01 6. 24E-01 

3.00E-01 S.2SE-02 2.56E-01 1. 66E-0l 1. 44E-01 6.1SE-0l 

4.00E-01 4.91E-02 2. 47E-01 1. 39E-01 1. 77E-01 6. 12E-01 

S.OOE-01 4.6SE-02 2.40E-01 1. 17E-Ol 2.03E-01 6.06E-01 

6.00E-Ol 4. 46E-02 2. 33E-01 9.S6E-02 2. 23E-01 S.99E-01 

7.00E-01 4. 31E-02 2. 27E-01 S.29E-02 2. 39E-01 S.91E-01 

S~OOE-01 4.20E-02 2. 21E-01 6. 97E-02 2.50E-01 S.S2E-Ol 

9.00E-01 4. 11E-02 2.16E-OI 5.S6E-02 2.57E-01 S.72E-01 

1.00E+OO 4.03E-02 2.11E-01 4. 93E-02 2.6IE-01 5.61E-01 

2.00E+OO 3. 76E-02 1.77E-01 S.72E-03 1.99E-01 4.23E-01 

3.00E+OO 3. 66E-02 1.60E-01 1. S4E-03 1.11E-OI 3.09E-01 

4.00E+OO 3. 59E-02 1.50E-01 2.72E-04 S.60E-02 2.42E-OI 

5.00E+OO 3. 52E-02 1.4SE-01 4.S2E-OS 2.7SE-02 2.0SE-OI 

6.00E+OO 3.47E-02 1.4IE-0l 8.S1E-06 1. 43E-02 I.90E-01 

7.00E+OO 3. 42E-02 1.3SE-01 I.51E-06 7. 96E-03 I.SOE-01 

S.OOE+OO 3.3SE-02 1. 36E-OI 2.66E-07 4. 93E-03 1.7SE-01 

9.00E+OO 3.3SE-02 1. 34E-01 4.70E-OS 3.47E-03 1.71E-01 

1.00E+Ol 3. 32E-02 1.32E-01 O.OOE+OO 2.76E-03 1.6SE-01 

2.00E+OI 3. 19E-02 1. 16E-01 O.OOE+OO 1.84E-03 1.50E-01 

3.00E+Ol 3.1SE-02 I.02E-01 O.OOE+OO 1.60E-03 I.35E-Ol 

4.00E+OI 3. 14E-02 9.01E-02 O.OOE+OO 1. 39E-03 1. 23E-01 

S.OOE+OI 3. 14E-02 7. 93E-02 O.OOE+OO 1.21E-OJ 1.l2E-Ol 

6.00E+OI 3.13E-02 6.9SE-02 O.OOE+OO I.OSE-03 1.02E-OI 

7.00E+OI 3. 13E-02 6.14E-02 O.OOE+OO 9.1SE-04 9. 36E-02 

S.OOE+01 3.12E-02 5.40E-02 O.OOE+OO 7. 99E-04 S.60E-02 

9.00E+01 3. 11E-02 4.7SE-02 O.OOE+OO 6.96E-04 7. 93E-02 

1.00E+02 3.10E-02 4.1SE-02 O.OOE+OO 6.0SE-04 7. 34E-02 

2.00E+02 2.S4E-02 1.lSE-02 O.OOE+OO 1. SlE-04 4.0lE-02 

3.00E+02 2. 47E-02 3.1SE-03 O.OOE+OO 3.7SE-OS 2. 79E-02 

4.00E+02 2.10E-02 S.55E-04 O.OOE+OO 9.46E-06 2.1SE-02 

S.OOE+02 1.77E-02 2. 31E-04 O.OOE+OO 2. 37E-06 1. 79E:"02 

6.00E+02 1. 49E-02 6.l9E-OS O.OOE+OO 5.9lE-07 1.50E-02 

7.00E+02 1.25E-02 1. 65E-05 O.OOE+OO 1.4SE-07 1. 26E-02 

8.00E+02 1.06E-02 4.40E-06 O.OOE+OO 3.70E-OS 1.06E-02 

9.00E+02 S.S7E-03 1. 16E-06 O.OOE+OO O.OOE+OO S.S7E-03 

I.OOE+03 7. 46E-03 3.0SE-07 O.OOE+OO O.OOE+OO 7. 46E-03 

2.00E+03 I.32E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 32E-03 

3.00E+03 2.33E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2.33E-04 

4.00E+03 4.13E-05 O.OOE+OO O.OO1i;+OO O.OOE+OO 4.13E-05 

5.00E+03 7.30E-06 O.OOE+OO O.OOE+OO O.OOE+OO 7.30E-06 

6.00E+03 1. 29E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 29E-06 

7.00E+03 2.2SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 2.2SE-07 

S.OOE+03 4.04E":"OS O.OOE+OO O.OOE+OO O.OOE+OO 4.04E-OS 

B-251 
CLASS W AHAD- 1 HICRON STABLE TIN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 7.60E-03 S.09E-06 

2.00E-Ol 1. 46E-02 1.63E-04 

3.00E-Ol 2.00E-02 S.24E-04 

4.00E-Ol 2. 42E-02 2.40E-03 

S.OOE-Ol 2. 76E-02 S.23E-03 

6.00E-Ol 3.02E-02 9.S2E-03 

7.00E-Ol 3. 23E-02 1.S4E-02 

S.OOE-Ol 3.41E-02 2. 27E-02 

9.00E-Ol 3.SSE-02 3.1SE-02 

1.OOE+OO 3. 66E-02 3. 66E-02 4.16E-02 4.16E-02 

2.00E+OO S.29E-03 4.19E-02 1.33E-0l 1.74E-Ol 

3.00E+OO 2.07E-03 4.40E-02 1.12E-Ol 2.S6E-Ol 

4.00E+OO 1.4SE-03 4.S4E-02 6. SOE-02 3. SlE-Ol 

S.OOE+OO 1.2SE-03 4.67E-02 3. 34E-02 3.SSE-Ol 

6.00E+OO 1.llE-03 4.7SE-02 1. 67E-02 4.01E-Ol 

7.00E+OO 1.OOE-03 4.SSE-02 S.SSE-03 4.lOE-Ol 

S.OOE+OO 9.17E-04 4. 97E-02 4.73E-03 4.1SE-Ol 

9.00E+OO S.4SE-04 S.06E-02 2.90E-03 4.1SE-Ol 

l.OOE+Ol 7.90E-04 S.l3E-02 2.03E-03 4.20E-Ol 

2.00E+Ol S.lSE-04 S.74E-02 1.06E-03 4. 32E-Ol 

3.00E+Ol 4. 27E-04 6.20E-02 9.2SE-04 4.42E-Ol 

4.00E+Ol 3. 77E-04 6.60E-02 S.06E-04 4.S0E-Ol 

S.OOE+Ol 3. 39E-04 6. 96E-02 7.01E-04 4.SSE-OI 

6.00E+OI 3.06E-04 7.2SE-02 6.llE-04 4. 64E-OI 

7.00E+Ol 2.7SE-04 7.S7E-02 S.3lE-04 4.70E-OI 

S.OOE+Ol 2.S3E-04 7.S3E-02 4. 63E-04 4.7SE-OI 

9.00E+OI 2.31E-04 S.07E-02 4.03E-04 4.79E-Ol 

I.OOE+02 2.11E-04 S.29E-02 3.SIE-04 4.S3E-Ol 

2.00E+02 9.90E-OS 9. 74E-02 S.77E-OS S.02E-OI 

3.00E+02 S.SlE-OS 1.OSE-Ol 2. 19E-OS S.06E-Ol 

4.00E+02 4.lOE-OS 1. IOE-Ol S.4SE-06 S.OSE-OI 

S.OOE+02 3.20E-OS I.I3E-Ol 1. 37E-06 S.OSE-OI 

6.00E+02 2. 62E-OS 1.I6E-OI 3. 42E-07 S.OSE-OI 

7.00E+02 2.19E-OS I.I9E-Ol S.S6E-OS S.OSE-OI 

S.OOE+02 1. S3E-OS I.2IE-Ol 2.14E-OS S.OSE-Ol .. "·1' . 9.00E+02 I.S4E-OS I.22E-OI O.OOE+OO S.OSE-Ol 

I.OOE+03 1.29E-OS 1.24E-0l O.OOE+OO S.OSE-OI 

2.00E+03 2. 29E-06 I.30E-Ol O.OOE+OO S.OSE-OI 

3.00E+03 4.0SE-07 1.31E-OI O.OOE+OO 5.0SE-OI 

4.00E+03 7. 16E-OS 1.31E-OI O.OOE+OO 5.0SE-Ol 

5.00E+03 1. 27E-OS 1.31E-OI O.OOE+OO 5.0SE-Ol 

B-252 
CLASS W AMAD = 1 MICRON STABLE TELLURIUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.01E-02 2.76E-Ol 2. 35E-01 5.54E-02 6. 37E-01 

2.00E-01 7.31E-02 2. 65E-01 1. 97E-0l 9.77E-02 6. 33E-01 

3.00E-01 7.7SE-02 2.56E-0l 1. 66E-01 1.30E-01 6.30E-01 

4.00E-01 S.26E-02 2. 47E-Ol 1. 39E-01 1. 56E-01 6. 25E-01 

5.00E-01 8.6SE-02 2.40E-0l 1. 17E-0l 1.76E-Ol 6.19E-01 

6.00E-Ol 9.01E-02 2. 33E-01 9. 86E-02 1.91E-01 6.12E-01 

7.00E-Ol 9.26E-02 2.27E-Ol S.29E-02 2.02E-Ol 6.04E-01 

8.00E-01 9.45E-02 2.21E-01 6. 97E-02 2.09E-Ol 5. 94E-01 

9.00E-01 9. 57E-02 2. 16E-01 5.S6E-02 2. 14E-01 5.S4E-01 

1.00E+OO 9. 64E-02 2.11E-0l 4. 93E-02 2.16E-01 5. 72E-Ol 

2.00E+OO 9. 14E-02 1.77E-01 S.72E-03 1.61E-Ol 4.3SE-01 

3.00E+OO "S.37E-02 1.60E-Ol 1. 54E-03 8.S7E-02 3. 34E-Ol 

4.00E+OO 7.8SE-02 1.50E-Ol 2.72E-04 4.47E-02 2. 74E-01 

5.00E+OO 7.59E-02 1. 45E-Ol 4.S2E-05 2. 22E-02 2. 43E-01 

6.00E+OO 7.42E-02 1.41E-01 S.51E-06 1.15E-02 2. 26E-01 

7.00E+OO 7.2gE-02 1. 38E-Ol 1. 51E-06 6.40E-03 2.17E-01 

S.OOE+OO 7.20E-02 1. 36E-Ol 2.66E-07 3.9SE-03 2. 12E-0l 

9.00E+OO 7.11E-02 1. 34E-Ol 4.70E-OS 2. 82E-03 2.0SE-01 

1.00E+01 7.04E-02 1.32E-0l O.OOE+OO 2.25E-03 2.05E-Ol 

2.00E+01 6.47E-02 1. 16E-01 O.OOE+OO 1. 51E-03 1. 82E-01 

3.00E+01 6.09E-02 1.02E-Ol O.OOE+OO 1.31E-03 1.65E-0l 

4.00E+01 5.S3E-02 9.01E-02 O.OOE+OO 1. 14E-03 1.50E-01 

5.00E+01 5. 66E-02 7.93E-02 O.OOE+OO 9. 93E-04 1.37E-0l 

6.00E+01 5.55E-02 6. 98E-02 O.OOE+OO 8. 65E-04 1. 26E-01 

7.00E+01 5.48E-02 6.14E-02 O.OOE+OO 7.53E-04 1.17E-0l 

8.00E+01 5.43E-02 5.40E-02 O.OOE+OO 6. 55E-04 1.09E-01 

9.00E+01 5.41E-02 4.75E-02 O.OOE+OO 5.71E-04 1.02E-01 

1.00E+02 5. 39E-02 4.1SE-02 O.OOE+OO 4. 97E-04 9. 62E-02 

2.00E+02 5.41E-02 1. 15E-02 O.OOE+OO 1.24E-04 6. 57E-02 

3.00E+02 5. 38E-02 3. 15E-03 O.OOE+OO 3.lOE-05 5.70E-02 

4.00E+02 5. 32E-02 S.55E-04 O.OOE+OO 7. 76E-06 5.41E-02 

5.00E+02 5. 25E-02 2.31E-04 O.OOE+OO 1. 94E-06 5. 28E-02 

6.00E+02 5.1SE-02 6. 19E-05 O.OOE+OO 4.S5E-07 5. 19E-02 

7.00E+02 5.11E-02 1.65E-05 O.OOE+OO 1.21E-07 5.11E-02 

S.OOE+02 5.04E-02 4.40E-06 O.OOE+OO 3.03E-OS 5.04E-02 

9.00E+02 4.97E-02 1.16E-06 O.OOE+OO O.OOE+OO 4. 97E-02 

1.00E+03 4.90E-02 3.0SE-07 O.OOE+OO O.OOE+OO 4.90E-02 

2.00E+03 4. 27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-02 

4.00E+03 3. 24E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 24E-02 

5.00E+03 2.S2E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S2E-02 

7.00E+03 2.14E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 14E-02 

S.OOE+03 1.S6E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.S6E-02 

1.00E+04 1.41E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.41E-02 

2.00E+04 3. 52E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 52E-03 

B-253 
CLASS W AHAD == 1 MICRON STABLE TELLURIUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-0l 1. 96E-03 6.60E-04 

2.00E-Ol 4.20E-03 1.S6E-03 

3.00E-Ol 6.48E-03 2. 94E-03 

4.00E-Ol 8. 83E-03 S.17E-03 

S.OOE-Ol 1.12E-02 8. S2E-03 

6.00E-Ol 1. 37E-02 1.3lE-02 

7.00E-Ol 1.61E-02 1.90E-02 

8.00E-Ol 1.8SE-02 2. 62E-02 

9.00E-Ol 2.09E-02 3.4SE-02 

1.OOE+OO 2. 32E-02 2. 32E-02 4. 39E-02 4. 39E-02 

2.00E+OO 1. 83E-02 4.lSE-02 1.16E-Ol 1.60E-Ol 

3.00E+OO 1.OSE-02 S.20E-02 9. 38E-02 2.S3E-Ol 

4.00E+OO S.83E-03 S.78E-02 S.40E-02 3.07E-Ol 

S.OOE+OO 3. 42E-03 6.l2E-02 2. 78E-02 3.3SE-Ol 

6.00E+OO 2. 24E-03 6.3SE-02 1.4lE-02 3. 49E-OI 

7.00E+OO 1.6SE-03 6.S1E-02 7.4lE-03 3.S7E-OI 

8.00E+OO I. 36E-03 6. 65E-02 4. 24E-03 3.6IE-0l 

9.00E+OO 1.20E-03 6.77E-02 2. 74E-03 3. 64E-OI 

1.OOE+OI 1.IIE-03 6. 88E-02 2. OlE-03 3. 66E-OI 

2.00E+Ol 8.3SE-04 7.8IE-02 1.15E-03 3. 79E-OI 

3.00E+OI 6.7lE-04 8.SSE-02 9.79E-04 3. 89E-Ol 

4.00E+Ol S.47E-04 9.lSE-02 8.40E-04 3. 98E-Ol 

S.OOE+OI 4.S2E-04 9.6SE-02 7.23E-04 4.06E-OI 

6.00E+OI 3.77E-04 1.00E-OI 6. 24E-04 4.l2E-Ol 

7.00E+OI 3.19E-04 I.04E-0l 5.40E-04 4.l8E-OI 

8.00E+OI 2.72E-04 I.07E-OI 4. 68E-04 4. 23E-Ol 

9.00E+Ol 2. 34E-04 I.09E-OI 4.07E-04 4. 28E-Ol 

1.OOE+02 2.02E-04 1.12E-OI 3.S4E-04 4.31E-Ol 

2.00E+02 S.96E-OS I.23E-OI 9.14E-OS 4.S0E-OI 

3.00E+02 2.lSE-OS 1.27E-OI 2.SIE-05 4.S6E-Ol 

4.00E+02 1.02E-OS 1. 28E-OI 7.86E-06 4.57E-Ol 

S.OOE+02 6. 78E-06 1. 29E-Ol 3. 38E-06 4. 58E-OI 

6.00E+02 5. 76E-06 1. 29E-Ol 2.20E-06 4. 58E-Ol 

7.00E+02 5. 42E-06 I.30E-Ol 1. 88E-06 4. 58E-Ol 

8.00E+02 5. 27E-06 1.3IE-OI 1.77E-06 4.58E-OI 

9.00E+02 5. 18E-06 1.3IE-OI 1. 73E-06 4. 58E-OI 

1.OOE+03 5.10E-06 1. 32E-OI 1.70E-06 4.58E-0l 

2.00E+03 4. 44E-06 1.36E-OI 1.48E-06 4.60E-Ol 

4.00E+03 3. 36E-06 1. 44E-Ol I.I2E-06 4. 63E-Ol 

5.00E+03 2. 93E-06 1.47E-OI 9. 76E-07 4.64E-Ol 

7.00E+03 2. 22E-06 1. 52E-Ol 7.40E-07 4. 65E-OI 

8.00E+03 1. 93E-06 1. 54E-Ol 6.44E-07 4. 66E-Ol 

I.OOE+04 1. 46E-06 1.58E-Ol 4.88E-07 4.67E-Ol 

2.00E+04 3. 66E-07 1. 66E-Ol 1. 22E-07 4.70E-0l 

8-254 
CLASS V AMAD = 1 MICRON STABLE LANTHANUK 139 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.lOE-02 2.76E-Ol 2.35E-Ol 5.72E-02 6.39E-Ol 

2.00E-Ol 7.11E-02 2. 65E-Ol 1. 97E-Ol 1.05E-Ol 6. 39E-Ol 

3.00E-Ol 7.l2E-02 2.56E-Ol 1. 66E-Ol 1.45E-Ol 6. 38E-Ol 

4.00E-Ol 7. 13E-02 2. 47E-Ol 1.39E-Ol 1.79E-Ol 6.37E-Ol 

5.00E-Ol 7.l4E-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6.34E-Ol 

6.00E-Ol 7.l5E-02 2.33E-Ol 9. 86E-02 2. 27E-Ol 6.30E-Ol 

7.00E-Ol 7.l6E-02 2.27E-Ol 8.29E-02 2.43E-Ol 6.24E-Ol 

8.00E-Ol 7.l6E-02 2.2lE-Ol 6. 97E-02 2. 54E-Ol 6.l6E-Ol 

9.00E-Ol 7.l7E-02 2.l6E-Ol 5. 86E-02 2.6lE-Ol 6.07E-Ol 

1.OOE+OO 7.l8E-02 2.11E-Ol 4. 93E-02 2. 65E-Ol 5. 97E-Ol 

2.00E+OO 7.24E-02 1.77E-Ol 8. 72E-03 2.03E-Ol 4. 62E-Ol 

3.00E+OO 7.29E-02 1.60E-Ol 1. 54E-03 1. 13E-Ol 3.47E-Ol 

4.00E+OO 7.34E-02 1.50E-Ol 2. 72E-04 5. 72E-02 2.8lE-0l 

5.00E+OO 7.39E-02 1. 45E-Ol 4. 82E-05 2. 85E-02 2.47E-Ol 

6.00E+OO 7.44E-02 1.4lE-Ol 8.5lE-06 1.47E-02 2.30E-Ol 

7~E+OO 7.48E-02 1. 38E-Ol 1.5lE-06 8. 13E-03 2.2lE-Ol 

8.00E+OO 7. 53E-02 1.36E-Ol 2. 66E-07 5.03E-03 2.l6E-Ol 

9.00E+OO 7. 58E-02 1.34E-Ol 4.70E-08 3. 54E-03 2. 13E-Ol 

1.OOE+Ol 7.62E-02 1.32E-Ol O.OOE+OO 2.8lE-03 2.11E-Ol 

2.00E+Ol 8.06E-02 1.16E-Ol O.OOE+OO 1.87E-03 1. 99E-Ol 

3.00E+Ol 8.45E-02 1.02E-Ol O.OOE+OO 1.63E-03 1. 88E-Ol 

4.00E+Ol 8.8lE-02 9.0lE-02 O.OOE+OO 1.42E-03 1.80E-Ol 

5.00E+Ol 9.l2E-02 7. 93E-02 O.OOE+OO 1.23E-03 1.72E-Ol 

6.00E+Ol 9.4lE-02 6. 98E-02 O.OOE+OO 1.07E-03 1. 65E-Ol 

7.00E+Ol 9.67E-02 6.l4E-02 O.OOE+OO 9. 35E-04 1.59E-Ol 

8.00E+Ol 9.89E-02 5.40E-02 O.OOE+OO 8.l4E-04 1. 54E-Ol 

9.00E+Ol 1.OlE-Ol 4. 75E-02 O.OOE+OO 7.09E-04 1.49E-Ol 

1.OOE+02 1.03E-Ol 4.l8E-02 O.OOE+OO 6. 17E-04 1.45E-Ol 

2.00E+02 1.12E-Ol 1.15E-02 O.OOE+OO 1.54E-04 1.24E-Ol 

3.00E+02 1.14E-Ol 3.l5E-03 O.OOE+OO 3. 86E-05 1. 17E-Ol 

4.00E+02 1.12E-Ol 8.55E-04 O.OOE+OO 9. 64E-06 1. 13E-Ol 

5.00E+02 1.llE-Ol 2.3lE-04 O.OOE+OO 2.4lE-06 1.llE-Ol 

6.00E+02 1.09E-Ol 6.l9E-05 O.OOE+OO 6.03E-07 1.09E-Ol 

7.00E+02 1.06E-Ol 1.65E-05 O.OOE+OO 1.5lE-07 1.06E-Ol 

8.00E+02 1.04E-0l 4.40E-06 O.OOE+OO 3.77E-08 1.04E-Ol 

9.00E+02 1.02E-Ol 1.16E-06 O.OOE+OO O.OOE+OO 1.02E-Ol 

1.OOE+03 1.OOE-Ol 3.08E-07 O.OOE+OO O.OOE+OO 1.OOE-0l ... ,. 2.00E+03 8.23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 23E-02 

4.00E+03 5. 54E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.54E-02 

5.00E+03 4. 54E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 54E-02 

7.00E+03 3.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.06E-02 

8.00E+03 2.5lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.5lE-02 

1.OOE+04 1.69E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.69E-02 

2.00E+04 2.33E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 33E-03 

B-255 
CLASS W AHAD == 1 MICRON STABLE LANTHAN1JM 139· 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ---------------------------~--------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.20E-06 8.l0E-06 

2.00E-Ol 2.6lE-06 1. 64E-04 

3.00E-Ol 4.02E-06 8. 29E-04 

4.00E-Ol s.43E-06 2. 42E-03 

s.OOE;-Ol 6. 84E-06 s.28E-03 

6.00E-Ol 8.26E-06 9.6lE-03 

7.00E-Ol 9. 67E-06 1.ssE-02 

B.OOE-Ol 1. 11E-Os 2.30E-02 

9.00E-01 1.2sE-Os 3.l9E-02 

1.00E+00 I.39E-Os I.39E-Os 4.2lE-02 4.21E-02 

2.00E+00 1.43E-Os 2.82E-Os I.3sE-0l 1. 77E-01 

3.00E+00 I.44E-Os 4. 26E-Os 1.14E-01 2. 92E-OI 

4.00E+OO 1.4sE-Os s.71E-Os 6.64E-02 3.s8E-01 

s.OOE+OO 1.46E-Os 7.l6E-Os 3.41E-02 3.92E-OI 

6.00E+00 I.47E-Os B.63E-Os 1.7IE-02 4.09E-01 

7.00E+00 l.4BE-Os 1.OlE-04 8.77E-03 4.1BE-OI 

8.00E+00 1.49E-Os 1.16E-04 4.83E-03 4.23E-01 

9.00E+00 I.sOE-Os 1.31E-04 2. 96E-03 4. 26E-Ol 

1.00E+01 I.sOE-Os I.46E-04 2.07E-03 4. 28E-Ol 

2.00E+Ol 1.s9E-Os 3.01E-04 I.OBE-03 4.40E-Ol 

3.00E+Ol 1.67E-Os 4.6sE-04 9.43E-04 4.s0E-01 

4.00E+Ol 1. 74E-Os 6. 36E-04 B.2lE-04 4.s9E-01 

s.OOE+Ol 1. BOE-Os B.13E-04 7.1sE-04 4.67E-01 

6.00E+Ol 1.B6E-Os 9. 97E-04 6.22E-04 4. 73E-Ol 

7.00E+Ol I.9IE-Os 1. 19E-03 s.42E-04 4.79E-Ol 

8.00E+Ol 1.96E-Os I. 38E-03 4.72E-04 4.B4E-Ol 

9.00E+OI 2.00E-Os 1.sBE-03 4.llE-04 4.BBE-Ol 

1.00E+02 2.03E-Os 1. 78E-03 3.s7E-04 4. 92E-01 

2.00E+02 2. 22E-Os 3. 93E-03 B.94E-Os s.llE-Ol 

3.00E+02 2.2sE-Os 6.l7E-03 2. 23E-Os s.16E-01 

4.00E+02 2.23E-Os 8.4IE-03 s.s9E-06 s.17E-01 

s.00E+02 2.l9E-Os 1.06E-02 1.40E-06 s.lBE-OI 

6.00E+02 2.lsE-Os I.2BE-02 3.49E-07 s.lBE-Ol 

7.00£+02 2.llE-Os 1. 49E-02 B.73E-08 s.18E-01 

B.00E+02 2.07E-Os 1.70E-02 2.18E-08 s.lBE-01 

9.00E+02 2.03E-Os I.90E-02 O.OOE+OO s.lBE-Ol 

I.00E+03 1.99E-Os 2.llE-02 O.OOE+OO s.18E-01 

2.00E+03 1.63E-Os 3.9lE-02 O.OOE+OO s.18E-01 

4.00E+03 1.lOE-Os 6.60E-02 O.OOE+OO s.lBE-01 

8.00E+03 4.97E-06 9.63E-02 O.OOE+OO s.lBE-Ol 

1.OOE+04 3.34E-06 1.04E-01 O.OOE+OO s.18E-01 

B-2s6 
CLASS W AMAD = 1 MICRON BALFLIFE= 1.68E+OO DAYS IANTHANIJM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 6.8IE-02 2.65E-OI 2.25E-OI 5.48E-02 6. 13E-OI 

2.00E-OI 6. 55E-02 2. 44E-OI 1. 82E-OI 9. 69E-02 5. 88E-OI 

3.00E-OI 6. 29E-02 2. 26E-OI 1.47E-OI 1. 29E-OI 5.64E-OI 

4.00E-OI 6.04E-02 2.1OE-Ol 1.18E-OI 1.5IE-OI 5.40E-OI 

5.00E-OI 5.8IE-02 1.95E-OI 9. 54E-02 1.67E-0l 5. 16E-Ol 

6.00E-OI 5. 58E-02 1.82E-OI 7.70E-02 1. 77E-OI 4.9IE-OI 

7.00E-OI 5. 36E-02 1.70E-0l 6.2IE-02 1. 82E-OI 4.67E-OI 

8.00E-OI 5.15E-02 1. 59E-OI 5.0IE-02 1. 82E-OI 4. 43E-OI 

9.00E-OI 4. 94E-02 1.49E-OI 4.04E-02 1.80E-OI 4. 19E-OI 

I.OOE+OO 4. 75E-02 1.39E-OI 3. 26E-02 1. 75E-OI 3. 95E-OI 

2.00E+OO 3.17E-02 7.76E-02 3. 82E-03 8.90E-02 2.02E-OI 

3.00E+OO 2. llE-02 4. 63E-02 4. 46E-04 3. 28E-02 I.OIE-OI 

4.00E+OO 1.4IE-02 2.88E-02 5.22E-05 1.IOE-02 5.39E-02 

5.00E+OO 9. 37E-03 1. 83E-02 6.IIE-06 3.6IE-03 3. 13E-02 

6.00E+OO 6. 24E-03 1.18E-02 7.14E-07 1.23E-03 1. 93E-02 

7.00E+OO 4.15E-03 7. 66E-03 8. 35E-08 4.5IE-04 1. 23E-02 

8.00E+OO 2. 76E-03 4.99E-03 O.OOE+OO 1.85E-04 7. 94E-03 

9.00E+OO 1. 84E-03 3. 25E-03 O.OOE+OO 8.6IE-05 5.18E-03 

1.00E+OI 1. 23E-03 2.12E-03 O.OOE+OO 4. 52E-05 3. 39E-03 

2.00E+Ol 2.08E-05 3.00E-05 O.OOE+OO 4. 83E-07 5. 13E-05 

3.00E+OI 3.5IE-07 4.25E-07 O.OOE+OO O.OOE+OO 7. 75E-07 

B-257 
CLASS W AMAD = 1 MICRON BALFLIFE= 1.688+00 DAYS LANTHANUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI l.lSE-06 7.77E-06 

2.00E-OI 2.40E-06 1.SlE-04 

3.00E-OI 3. SSE-06 7.32E-04 

4.00E-Ol 4.60E-06 2.0SE-03 

S.OOE-OI S. S7E-06 4. 29E-03 

6.00E-OI 6.4SE-06 7.S0E-03 

7.00E-OI 7.2SE-06 1.16E-02 

8.00E-OI 7. 97E-06 1.6SE-02 

9.00E-OI 8. 63E-06 2.20E-02 

1.00E+OO 9. 22E-06 9. 22E-06 2. 79E-02 2. 79E-02 

2.00E+OO 6.2SE-06 1. 23E-OS S.92E-02 7. 76E-02 

3.00E+OO 4.16E-06 I. 23E-OS 3.31E-02 8. 44E-02 

4.00E+OO 2.77E-06 1.09E-OS 1.27E-02 6. 86E-02 

S.OOE+OO 1.8SE-06 9.08E-06 4. 33E-03 4.97E-O? 

6.00E+OO I. 23E-06 7.24E-06 1.43E-03 3. 43E-02 

7.00E+OO 8.20E-07 S.61E-06 4.87E-04 2. 32E-02 

8.00E+OO S.46E-07 4.26E-06 1. 77E-04 I.SSE-02 

9.00E+OO 3. 63E-07 3. 18E-06 7.20E-OS I.03E-02 

I.OOE+OI 2. 42E-07 2.35E-06 3.32E-05 6. 88E-03 

B-258 
CLASS W AHA» ... 1 MICRON STABLE CER.IUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.10E-02 2.76E-Ol 2.3SE-Ol S.72E-02 6.39E-Ol 

2.00E-Ol 7.11E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 39E-Ol 

3.00E-Ol 7.12E-02 2.S6E-Ol 1.66E-Ol 1.46E-Ol 6.3SE-Ol 

4.00E-Ol 7.12E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.37E-Ol 

S.OOE-Ol 7.l3E-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6. 34E-Ol 

6.00E-Ol 7.14E-02 2. 33E-Ol 9.S6E-02 2.27E-Ol 6.30E-Ol 

7.00E-Ol 7.14E-02 2.27E-Ol S.29E-02 2. 43E-Ol 6.24E-Ol 

S.OOE-Ol 7.1SE-02 2.21E-Ol 6. 97E-02 2.S4E-Ol 6.16E-Ol I 9.00E-Ol 7.lSE-02 2.16E-Ol S.S6E-02 2.6lE-Ol 6.oiE-Ol 

1.OOE+OO 7.16E-02 2.1lE-Ol 4. 93E-02 2.6SE-Ol S.97E-Ol 

2.00E+OO 7.2lE-02 1. 77E-Ol S.72E-03 2.03E-Ol 4.62E-Ol 

3.00E+OO 7.26E-02 1.60E-Ol 1.S4E-03 1.l3E-Ol 3. 47E-Ol 

4.00E+OO 7.31E-02 1. SOE-Ol 2.72E-04 S.72E-02 2.S1E-Ol 

S.OOE+OO 7. 36E-02 1.4SE-Ol 4.S2E-OS 2.SSE-02 2. 47E-Ol 

6.00E+OO 7.4lE-02 1.41E-Ol S.SlE-06 1.47E-02 2.30E-Ol 

7.00E+OO 7.4SE-02 1.3SE-Ol 1.SlE-06 S.14E-03 2.2lE-Ol 

S.OOE+OO 7.S0E-02 1.36E-Ol 2. 66E-07 S.04E-03 2.16E-Ol 

9.00E+OO 7.SSE-02 1. 34E-Ol 4.70E-OS 3.SSE-03 2.13E-Ol 

1.OOE+Ol 7. S9E-02 1.32E-Ol O.OOE+OO 2. S2E-03 2.llE-Ol 

2.00E+Ol S.03E-02 1.16E-Ol O.OOE+OO 1.87E-03 1.9SE-Ol 

3.00E+Ol S.42E-02 1.02E-Ol O.OOE+OO 1. 63E-03 1. SSE-OI 

4.00E+OI S.77E-02 9.0IE-02 O.OOE+OO 1. 42E-03 1. 79E-Ol 

S.OOE+OI 9.09E-02 7.93E-02 O.OOE+OO I.13E-03 1.7lE-OI 

6.00E+Ol 9.3SE-02 6.9SE-02 O.OOE+OO I.07E-03 I.6SE-Ol 

7.00E+OI 9.63E-02 6.14E-02 O.OOE+OO 9.36E-04 1. S9E-OI 

S.OOE+OI 9.S6E-02 S.40E-02 O.OOE+OO S.ISE-04 I.S3E-OI 

9.00E+OI I.OIE-OI 4.7SE-02 O.OOE+OO 7.09E-04 1. 49E-OI 

1.OOE+02 I.02E-Ol 4.lSE-02 O.OOE+OO 6.17E-04 I.4SE-OI 

2.00E+02 I.I2E-OI 1.lSE-02 O.OOE+OO 1. S4E-04 1.23E-Ol 

3.00E+02 I.l3E-OI 3.lSE-03 O.OOE+OO 3.S6E-OS I.I6E-OI 

4.00E+02 I.I2E-OI S. SSE-04 O.OOE+OO 9.6SE-06 1.I3E-Ol 

S.OOE+02 1. IOE-OI 2.3IE-04 O.OOE+OO 2.4IE-06 1.lOE-OI 

6.00E+02 I.OSE-OI 6.l9E-OS O.OOE+OO 6.03E-07 1.OSE-Ol 

7.00E+02 I.06E-OI I.6SE-OS O.OOE+OO I.SIE-07 I.06E-OI 

8.00E+02 I.04E-OI 4.40E"'06 O.OOE+OO 3.77E-OS I.04E-OI 

9.00E+02 I.02E-OI I.I6E-06 O.OOE+OO O.OOE+OO I.02E-OI 

I.OOE+03 1.00E-OI 3.0SE-07 O.OOE+OO O.OOE+OO I.OOE-OI 

2.00E+03 S.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.20E-02 

4.00E+03 S.S2E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.S2E-02 

S.OOE+03 4.S3E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.S3E-02 

7.00E+03 3.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.0SE-02 

S.OOE+03 2.S0E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S0E-02 

I.OOE+04 1.6SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 68E-02 

2.00E+04 2. 32E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 32E-03 

B-2S9 
CLASS W AHAD ... 1 MICH.oR STABLE CERIUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.20E-06 B.IOE-06 

2.00E-OI 2.6IE-06 1. 64E-04 

3.00E-OI 4.02E-06 B.29E-04 

4.00E-OI S.43E-06 2. 42E-03 

S.OOE-Ol 6. B4E-06 S.2BE-03 

6.00E-Ol B.2SE-06 9.61E-03 

7.00E-OI 9. 67E-06 I.SSE-02 

B.OOE-OI 1. lIE-OS 2.30E-02 

9.00E-Ol I.2SE-OS 3.19E-02 

1.00E+00 1. 39E-OS 1. 39E-OS 4.21E-02 4.21E-02 

2.00E+00 I.42E-OS 2.BIE-OS 1.3SE-Ol 1.77E-Ol 

3.00E+00 1. 43E-OS 4.2SE-OS I.I4E-Ol 2. 92E-OI 

4.00E+00 1. 44E-OS S •. 69E-OS 6.6SE-02 3. SBE-Ol 

S.OOE+OO 1.4SE-OS 7.14E-OS 3. 42E-02 3. 92E-Ol 

6.00E+00 1.46E-OS B.60E-OS I.71E-02 4.09E-OI 

7.00E+00 1. 47E-OS 1.0IE-04 B.7BE-03 4.IBE-Ol 

B.OOE+OO I.4BE-OS 1. 16E-04 4. B4E-03 4. 23E-OI 

9.00E+00 1.49E-OS 1.30E-04 2. 97E-03 4. 26E-Ol 

1.00E+Ol I.S0E-OS 1.4SE-04 2.07E-03 4.2BE-Ol 

2.00E+Ol I.S9E-OS 3.00E-04 1.09E-03 4.40E-OI 

3.003:+01 1. 66E-OS 4.63E-04 9. 44E-04 4.SIE-Ol 

4.00E+Ol 1.73E-OS 6. 33E-04 8. 22E-04 4.S9E-Ol 

S.OOE+Ol 1. BOE-OS B.I0E-04 7.1SE-04 4.67E-Ol 

6.00E+Ol 1. BSE-OS 9. 93E-04 6. 23E-04 4. 74E-OI 

7.00E+Ol 1.90E-OS I.IBE-03 S.42E-04 4. 79E-Ol 

B.OOE+OI 1.9SE-OS 1. 37E-03 4.72E-04 4.B4E-Ol 

9.00E+Ol 1. 99E-OS I.S7E-03 4.l1E-04 4.B9E-Ol 

1.00E+02 2.03E-OS 1.77E-03 3.S8E-04 4. 93E-Ol 

2.00E+02 2. 21E-OS 3. 91E-03 8. 94E-OS S.12E-Ol 

3.00E+02 2. 24E-OS 6.1SE-03 2. 24E-OS S.17E-Ol 

4.00E+02 2. 22E-OS B.38E-03 S.S9E-06 S.IBE-Ol 

S.00E+02 2. 18E-OS 1.06E-02 1.40E-06 S.IBE-Ol 

6.00E+02 2. 14E-OS 1.27E-02 3. 49E-07 S.IBE-Ol 

7.00E+02 2.lOE-OS 1. 49E-02 B.73E-OB S.18E-Ol 

B.00E+02 2.06E-OS 1. 69E-02 2. 18E-OS S.IBE-Ol 

9.00E+02 2.02E-OS 1.90E-02 O.OOE+OO S.IBE-OI 

1.00E+03 I.9BE-OS 2.10E-02 O.OOE+OO S.IBE-Ol 

2.00E+03 1. 62E-OS 3.90E-02 O.OOE+OO S.IBE-Ol 

4.00E+03 I.09E-OS 6.SBE-02 O.OOE+OO S.IBE-Ol 

B.00E+03 4.9SE-06 9.60E-02 O.OOE+OO S.IBE-Ol 

1.00E+04 3. 33E-06 I.04E-OI O.OOE+OO S.IBE-Ol 

B-260 
ClASS W AHAD = 1 KICRON IJALFLIFE= l.2SE+Ol DAYS CERIUH 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.0BE-02 2.76E-Ol 2. 34E-Ol 5.70E-02 6.3BE-0l 

2.00E-Ol 7.0BE-02 < 2. 64E-Ol 1. 96E-Ol 1.05E-Ol 6. 36E-Ol 

3.00E-Ol 7.07E-02 2. 54E-Ol 1. 65E-Ol 1. 45E-Ol 6. 34E-Ol 

4.00E-Ol 7.06E-02 2. 45E-Ol 1.3BE-Ol 1. 17E-Ol 6.3lE-Ol 

5.00E-Ol 7.05E-02 2. 37E-Ol 1.16E-0l 2.03E-Ol 6.27E-Ol 

6.00E-Ol 7.04E-02 2.30E-Ol 9. 74E-02 2. 24E-Ol 6.21E-Ol 

7.00E-Ol 7.04E-02 2. 23E-Ol B.17E-02 2. 39E-Ol 6. 14E-Ol 

B.OOE-Ol 7.03E-02 2.l7E-Ol 6.B6E-02 2.50E-Ol 6.06E-Ol 

9.00E-Ol 7.02E-02 2. 11E-Ol 5.75E-02 2. 56E-Ol 5. 96E-Ol 

1.OOE+OO 7.01E-02 2.06E-Ol 4.B3E-02 2.60E-Ol 5.B4E-Ol 

2.00E+OO 6.91E-02 1.70E-OI B.35E-03 1.95E-Ol 4. 42E-Ol 

3.00E+OO 6.81E-02 1.50E-OI 1. 45E-03 1.06E-Ol 3. 26E-Ol 

4.00E+OO 6.7lE-02 1.3BE-OI 2.50E-04 5. 25E-02 2.5BE-Ol 

5.00E+OO 6.6lE-02 1.30E-Ol 4. 33E-05 2. 56E-02 2. 22E-Ol 

6.00E+OO 6.52E-02 1. 24E-Ol 7. 49E-06 1.29E-02 2.02E-Ol 

7.00E+J)O 6.42E-02 1. 19E-Ol 1.30E-06 7.0lE-03 1.90E-OI 

8.00E+OO 6. 32E-02 1. 15E-Ol 2. 24E-07 4. 25E-03 1.B2E-Ol 

9.00E+OO 6. 23E-02 1.11E-Ol 3.BBE-08 2. 93E-03 1. 76E-Ol 

1.OOE+Ol 6.13E-02 1.07E-Ol O.OOE+OO 2.2BE-03 1.70E-Ol 

2.00E+Ol 5. 24E-02 7.59E-02 O.OOE+OO 1. 22E-03 1.29E-Ol 

3.00E+Ol 4.44E-02 5.40E-02 O.OOE+OO B.59E-04 9.92E-02 

4.00E+Ol 3. 74E-02 3.B4E-02 O.OOE+OO 6.04E-04 7. 64E-02 

5.00E+Ol 3. 13E-02 2. 73E-02 O.OOE+OO 4.25E-04 5.90E-02 

6.00E+Ol 2.6lE-02 1. 94E-02 O.OOE+OO 2. 99E-04 4. 58E-02 

7.00E+Ol 2. 16E-02 1. 38E-02 O.OOE+OO 2.lOE-04 3. 56E-02 

8.00E+Ol 1. 79E-02 9.80E-03 O.OOE+OO 1.48E-04 2. 79E-02 

9.00E+Ol 1. 48E-02 6. 97E-03 O.OOE+OO 1.04E-04 2.1BE-02 

1.OOE+02 1.2lE-02 4. 95E-03 O.OOE+OO 7.32E-05 1.72E-02 

2.00E+02 1.57E-03 1. 62E-04 O.OOE+OO 2.l7E-06 1. 73E-03 

3.00E+02 1.BBE-04 5. 25E-06 O.OOE+OO 6.42E-08 1. 94E-04 

4.00E+02 2.2lE-05 1.69E-07 O.OOE+OO O.OOE+OO 2. 23E-05 

5.00E+02 2.5BE-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.5BE-06 

6.00E+02 3.00E-07 O.OOE+OO O.OOE+OO O.OOE+OO 3.00E-07 

7.00E+02 3.4BE-08 O.OOE+OO O.OOE+OO O.OOE+OO 3.4BE-08 

B-26l 
CLASS W .AMAD - 1 MICRON BALFLIFE== 3.25£+01 DAYS CBB.IUK 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------~------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES fECES 

I.OOE-OI 1.20E-06 S.OSE-06 

2.00E-OI 2.60E-06 1. 63E-04 

3.00E-OI 3. 99E-06 S.24E-04 

4.00E-OI S.3SE-06 2.40E-03 

S.OOE-OI 6.77E-06 S.22E-03 

6.00E-OI S.ISE-06 9.49E-03 

7.00E-OI 9.S2E-06 I. S3E-02 

B.OOE-OI I.09E-OS 2. 26E-02 

9.00E-OI 1. 23E-OS 3.13E-02 

I.OOE+OO I. 36E-OS 1.36E-OS 4.13E-02 4.13E-02 

2.00E+OO 1. 36E-OS 2.70E-OS 1.30E-0l I.70E-0l 

3.00E+OO 1. 34E-OS 3.9BE-OS I.07E-OI 2: 74E-OI 

4.00E+OO 1. 32E-OS S.22E-OS 6.lOE-02 3. 29E-OI 

S.OOE+OO I.3IE-OS 6. 42E-OS 3.07E-02 3. S3E-OI 

6.00E+OO I. 29E-OS 7.S7E-OS I. SOE-02 3.60E-OI 

7.00E+OO I. 27E-OS S.6SE-OS 7.S6E-03 3.60E-OI 

S.OOE+OO I.2SE-OS 9. 74E-OS 4.0BE-03 3. S7E-OI 

9.00E+OO 1.23E-OS I.OSE-04 2.4SE-03 3.S2E-OI 

I.OOE+OI 1.2IE-OS I.I7E-04 1.67E-03 3. 46E-OI 

2.00E+OI I.03E-OS I. 96E-04 7.0SE-04 2.SSE-OI 

3.00E+OI S.77E-06 2.44E-04 4.9SE-04 2.3SE-OI 

4.00E+OI 7. 39E-06 2.70E-04 3.S0E-04 I. 96E-OI 

S.OOE+OI 6.19E-06 2. 79E-04 2.46E-04 1.6IE-OI 

6.00E+OI S.16E-06 2. 76E-04 1. 73E-04 I. 32E-OI 

7.00E+OI 4.2SE-06 2.6SE-04 1. 22E-04 I.OSE-OI 

S.OOE+OI 3.S4E-06 2.50E-04 S. S7E-OS 8. 79E-02 

9.00E+OI 2. 92E-06 2.3IE-04 6.03E-OS 7.17E-02 

I.OOE+02 2.40E-06 2. IOE-04 4. 24E-05 5. 84E-02 

2.00E+02 3.IIE-07 5.S0E-05 1. 26E-06 7.19E-03 

3.00E+02 3. 73E-OS I.02E-05 3. 72E-OS S.60E-04 

B-262 
CLASS W AHAD = 1 KICRON HA.LFLIFE- 2.84E+02 DAYS CEltIUH 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7.10E-02 2.76E-01 2.35E-01 5.71E-02 6. 39E-01 

2.00E-01 7.11E-02 2. 65E-01 1. 97E-01 1.05E-01 6.39E-01 

3.00E-01 7. 11E-02 2. 56E-01 1.66E-01 1. 45E-01 6. 38E-01 

4.00E-01 7. 12E-02 2. 47E-01 1. 39E-01 1. 79E-01 6. 36E-01 

5.00E-01 7. 12E-02 2.39E-01 1. 17E-01 2.05E-01 6.33E-01 

6.00E-01 7. 12E-02 2. 32E-01 9. 85E-02 2.26E-01 6. 29E-Ol 

7.00E-01 7. 13E-02 2. 26E-01 8. 28E-02 2.42E-01 6.23E-01 

8.00E-01 7. 13E-02 2.20E-01 6. 96E-02 2. 54E-01 6. 15E-01 

9.00E-01 7. 14E-02 2. 15E-01 5.85E-02 2.61E-01 6.06E-01 

1.00E+00 7. 14E-02 2.10E-01 4. 92E-02 2. 65E-01 5. 96E-01 

2.00E+00 . 7.18E-02 1.76E-01 8. 68E-03 2.03E-01 4. 59E-01 

3.00E+00 7.21E-02 1. 59E-01 1. 53E-03 1. 12E-01 3. 45E-Ol 

4.00E+00 7.24E-02 1.49E-01 2.70E-04 5.67E-02 2. 78E-01 

5.00E+00 7.27E-02 1. 43E-01 4. 76E-05 2. 81E-02 2. 44E-01 

6.0gf.+00 7.30E-02 1. 39E-01 8. 39E-06 1. 45E-02 2.26E-01 

7.0 E+OO 7.33E-02 1. 36E-01 1. 48E-06 8.00E-03 2. 17E-01 

8.00E+00 7.36E-02 1.33E-01 2.61E-07 4. 94E-03 2. 12E-01 

9.00E+00 7.38E-02 1.31E-01 4.60E-08 3. 47E-03 2.08E-01 

1.00E+01 7.41E-02 1.29E-01 O.OOE+oo 2.75E-03 2.06E-01 

2.00E+01 7. 65E-02 1.llE-01 O.OOE+OO 1. 78E-03 1. 89E-01 

3.00E+Ol 7. 83E-02 9.51E-02 O.OOE+oo 1.51E-03 1.75E-Ol 

4.00E+01 7. 96E-02 8. 17E-02 O.OOE+OO . 1.29E-03 1. 63E-Ol 

5.00E+01 8.05E-02 7.02E-02 O.OOE+OO 1.09E-03 1.52E-01 

6.00E+01 8.10E-02 6.03E-02 O.OOE+OO 9. 29E-04 1. 42E-01 

7.00E+01 8. 12E-02 5. 17E-02 O.OOE+OO 7. 89E-04 1. 34E-01 

8.00E+01 8.llE-02 4. 44E-02 O.OOE+OO 6.70E-04 1. 26E-01 

9.00E+01 8.08E-02 3. 81E-02 O.OOE+oo 5. 69E-04 1.20E-Ol 

1.00E+02 8.03E-02 3. 27E-02 O.OOE+OO 4. 84E-04 1. 13E-01 

2.00E+02 6. 87E-02 7.08E-03 O.OOE+OO 9. 48E-05 7.58E-02 

3.00E+02 5. 45E-02 1. 52E-03 O.OOE+OO 1. 86E-05 5.60E-02 

4.00E+02 4. 23E-02 3.23E-04 O.OOE+oo 3. 64E-06 4.26E-02 

5.00E+02 3. 26E-02 6. 82E-05 O.OOE+OO 7. 13E-07 3. 27E-02 

6.00E+02 2. 51E-02 1. 43E-05 O.OOE+oo 1.40E-07 2. 51E-02 

7.00E+02 1. 93E-02 3.00E-06 O.OOE+OO 2. 74E-08 1. 93E-02 

8.00E+02 1.48E-02 6.25E .... 07 O.OOE+OO O.OOE+OO 1.48E-02 

9.00E+02 1. 14E-02 1.30E-07 O.OOE+OO O.OOE+OO 1. 14E-02 

1.00E+03 8. 73E-03 2. 69E-08 O.OOE+oo O.OOE+oo 8.73E-03 ' .. :' . 2.00E+03 6. 26E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.26E-04 

3.00E+03 4. 48E-05 O.OOE+OO O.OOE+oo O.OOE+OO 4. 48E-05 

4.00E+03 3.21E-06 O.OOE+OO O.OOE+OO O.OOE+OO 3. 21E-06 

5.00E+03 2.30E-07 O.OOE+OO O.OOE+oo O.OOE+OO 2.30E-07 

6.00E+03 1. 65E-08 O.OOE+OO O.OOE+OO O.OOE+OO 1. 65E-08 

B-263 
CLASS II AMAD = 1 MICRON HALFLIFE= 2.84E+02 DAYS CERIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------- 24-HOUR . ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.20E-06 B.lOE-06 

2.00E-Ol 2.6lE-06 1. 64E-04 

3.00E-0l 4.02E-06 B.2BE-04 

4.00E-Ol 5.42E-06 2.42E-03 

5.00E-Ol 6.B3E-06 5. 27E-03 

6.00E-Ol 8. 24E-06 9.60E-03 

7.00E-Ol 9. 65E-06 1. 55E-02 

B.OOE-Ol 1.llE-05 2.29E-02 

9.00E-Ol 1.25E-05 3.lBE-02 

1.OOE+OO 1. 39E-05 1. 39E-05 4.20E-02 4.20E-02 

2.00E+OO 1.42E-05 2. BOE-05 1.35E-0l 1. 17E-01 

3.00E+OO 1. 42E-05 4.22E-05 1. 13E-01 2.90E-01 

4.00E+OO 1.43E-05 5.63E-05 6.5BE-02 3. 55E-01 

5.00E+OO 1.43E-05 7.05E-05 3. 37E-02 3.B8E-Ol 

6.00E+OO 1. 44E-05 B.4BE-05 1.6BE-02 4.04E-Ol 

7.00E+OO 1. 45E-05 9.90E-05 B.63E-03 4.l1E-Ol 

B.OOE+OO 1.45E-05 1.13E-04 4. 74E-03 4.15E-Ol 

9.00E+OO 1. 46E-05 1.28E-04 2.90E-03 4. 17E-01 

1.00E+Ol 1.46E-05 1.42E-04 2.02E-03 4.1BE-01 

2.00E+Ol 1.51E-05 2.B6E-04 1.03E-03 4. 19E-Ol 

3.00E+01 1. 55E-05 4.30E-04 B.17E-04 4.l9E-Ol 

4.00E+Ol 1. 57E-05 5. 74E-04 7. 45E-04 4.l7E-Ol 

5.00E+01 1. 59E-05 7.17E-04 6.33E-04 4.13E-0l 

6.00E+01 1.60E-05 8.5BE-04 5.3BE-04 4.09E-01 

7.00E+Ol 1.61E-05 9. 96E-04 4.57E-04 4.0~Ol 

B.OOE+Ol 1.60E-05 1.l3E-03 3.8BE-04 3. 99E-01 

9.00E+Ol 1.60E-05 1.26E-03 3.30E-04 3. 92E-Ol 

1.OOE+02 1. 59E-05 1. 39E-03 2. BOE-04 3.B6E-01 

2.00E+02 1. 36E-05 2.40E-03 5. 49E-05 3. 14E-01 

3.00E+02 1. OBE-O~ 2. 96E-03 1.0BE-05 2. 49E-Ol 

4.00E+02 B.37E-06 3. 16E-03 2.11E-06 1.95E-Ol 

5.00E+02 6. 45E-06 3.13E-03 4.13E-07 1. 53E-01 

6.00E+02 4. 96E-06 2. 95E-03 B.09E-OB 1.20E-01 

7.00E+02 3.B1E-06 2.70E-03 1.5BE-OB 9.40E-02 

B.OOE+02 2. 93E-06 2.41E-03 O.OOE+OO 7. 37E-02 

9.00E+02 2. 25E-06 2.l2E-03 O.OOE+OO 5.77E-02 

1.OOE+03 1. 73E-06 1.B3E-03 O.OOE+OO 4. 52E-02 

2.00E+03 1. 24E-07 2. 97E-04 O.OOE+OO 3. 95E-03 

B-264 
CLASS V AHAD = 1 MICRON STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.9SE-02 2. 76E-Ol 2.35E-Ol 5.72E-02 6. 38E-Ol 

2.00E-Ol 6.82E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 36E-Ol 

3.00E-Ol 6.72E-02 2.56E-Ol 1.66E-01 1. 46E-0l 6. 34E-Ol 

4.00E-Ol 6.6SE-02 2.47E-Ol 1. 39E-Ol 1. 79E-Ol 6.32E-01 

5.00E-Ol 6. 59E-02 2.40E-Ol 1. 17E-Ol 2.06E-0l 6.28E-Ol 

6.00E-Ol 6.S5E-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6. 24E-01 

7.00E-Ol 6. 52E-02 2. 27E-Ol 8.29E-02 2.43E-Ol 6.l7E-0l 

8.00E-01 6.50E-02 2.2lE-Ol 6. 97E-02 2. 54E-Ol 6.lOE-Ol 

9.00E-01 6. 48E-02 2.l6E-Ol 5.86E-02 2.6lE-0l 6.00E-Ol 

1.OOE+OO 6.47E-02 2.llE-Ol 4. 93E-02 2.6SE-Ol 5.90E-Ol 

2.00E+OO 6.45E-02 1.77E-Ol 8.72E-03 2.03E-0l 4. 54E-Ol 

3.00E+OO 6.47E-02 1.60E-Ol 1. 54E-03 1.13E-Ol 3.39E-Ol 

4.00E+OO 6. 49E-02 1.SOE-Ol 2. 72E-04 S.72E-02 2. 73E-Ol 

5.00E+OO 6. 52E-02 1.4SE-Ol 4. 82E-OS 2.8SE-02 2. 38E-Ol 

6.00E+OO 6. 54E-02 1.4lE-Ol 8.SlE-06 1.47E-02 2.2lE-Ol 

7.00E+OO 6. 57E-02 1. 38E-Ol 1.SlE-06 8.l4E-03 2.l2E-Ol 

8.00E+OO 6.60E-02 1.36E-0l 2. 66E-07 5.04E-03 2.07E-Ol 

9.00E+OO 6. 62E-02 1. 34E-Ol 4.70E-08 3.S5E-03 2.04E":'Ol 

1.OOE+Ol 6.6SE-02 1.32E-Ol O.OOE+OO 2. 82E-03 2.0lE-0l 

2.00E+Ol 6. 94E-02 1. 16E-Ol O.OOE+OO 1. 87E-03 1. 87E-Ol 

3.00E+Ol 7.23E-02 1.02E-Ol O.OOE+OO 1. 63E-03 1. 76E-Ol 

4.00E+Ol 7.5lE-02 9.0lE-02 O.OOE+OO 1.42E-03 1. 67E-Ol 

5.00E+Ol 7. 77E-02 7.93E-02 O.OOE+OO 1. 23E-03 1.S8E-Ol 

6.00E+Ol 8.00E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.SlE-Ol 

7.00E+Ol 8.2IE-02 6.l4E-02 O.OOE+OO 9.36E-04 1.44E-Ol 

8.00E+Ol 8.40E-02 5.40E-02 O.OOE+OO 8.ISE-04 1.39E-Ol 

9.00E+OI 8. 57E-02 4.7SE-02 O.OOE+OO 7.09E-04 1.34E-Ol 

1.OOE+02 8.72E-02 4.18E-02 O.OOE+OO 6.17E-04 1.30E-OI 

2.00E+02 9.SIE-02 l.lSE-02 O.OOE+OO 1.54E-04 1.07E-OI 

3.00E+02 9. 63E-02 3.ISE-03 O.OOE+OO 3. 86E-OS 9.9SE-02 

4.00E+02 9.S3E-02 8.SSE-04 O.OOE+OO 9.65E-06 9. 62E-02 

S.OOE+02 9.37E-02 2.3IE-04 O.OOE+OO 2.4IE-06 9.40E-02 

6.00E+02 9.20E-02 6.l9E-OS O.OOE+OO 6.03E-07 9.20E-02 

7.00E+02 9.02E-02 1.6SE-05 O.OOE+OO I.SIE-07 9.02E-02 

8.00E+02 8. 84E-02 4.40E--06 O.OOE+OO 3.77E-08 8. 84E-02 

9.00E+02 8.67E-02 1.16E-06 O.OOE+OO O.OOE+OO 8. 67E-02 

1.OOE+03 8.50E-02 3.08E-07 O.OOE+OO O.OOE+OO 8.50E-02 

2.00E+03 6. 97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 97E-02 

4.00E+03 4. 69E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 69E-02 

5.00E+03 3.8SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.8SE-02 

7.00E+03 2.S9E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S9E-02 

8.00E+03 2.13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.13E-02 

1.OOE+04 1.43E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.43E-02 

2.00E+04 1.98E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 98E-03 

B-265 
CLASS W AMAD ... 1 MICRON STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACClJt.IULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.S2E-03 8.10E-06 

2.00E-OI 2.90E-03 1. 64E-04 

3.00E-OI 3. 96E-03 8. 29E-04 

4.00E-Ol 4. 77E-03 2. 42E-03 

S.OOE-OI S.39E-03 S.28E-03 

6.00E-OI S.86E-03 9.6IE-03 

7.00E-OI 6. 23E-03 I.SSE-02 

8.00E-OI 6.S2E-03 2.30E-02 

9.00E-OI 6.7SE-03 3.19E-02 

I.OOE+OO 6. 92E-03 6. 92E-03 4.2IE-02 4.2IE-02 

2.00E+OO 7.26E-04 7.6SE-03 1.3SE-OI 1.77E-OI 

3.00E+OO 3.03E-04 7.9SE-03 1.14E-OI 2. 92E-OI 

4.00E+OO 2. 64E-04 8. 22E-03 6.6SE-02 3.s8E-OI 

s.OOE+OO 2.S0E-04 8.47E-03 3. 42E-02 3. 92E-OI 

6.00E+OO 2. 39E-04 8.7IE-03 1.7IE-02 4.09E-0l 

7.00E+OO 2. 28E-04 8. 93E-03 8. 78E-03 4.18E-OI 

8.00E+OO 2.l8E-04 9.lsE-03 4. 84E-03 4. 23E-OI 

9.00E+OO 2.09E-04 9. 36E-03 2. 97E-03 4. 26E-OI 

I.OOE+Ol 2.00E-04 9.s6E-03 . 2.07E-03 4.28E-Ol 

2.00E+Ol 1. 38E-04 1.12E-02 1.09E-03 4.40E-Ol 

3.00E+OI 1.04E-04 1.24E-02 9.44E-04 4.slE-0l 

4.00E+OI ·8.s0E-Os 1.33E-02 8. 22E-04 4.s9E-Ol 

s.OOE+OI 7. 32E-Os 1.4lE-02 7.lsE-04 4.67E-OI 

6.00E+OI 6.s3E-Os 1. 48E-02 6. 23E-04 4. 74E-OI 

7.00E+OI s.9SE-Os 1.S4E-02 S.42E-04 4.79E-OI 

8.00E+Ol s.49E-OS 1.s9E-02 4. 72E-04 4. 84E-OI 

9.00E+OI s.llE-OS 1.6sE-02 4.11E-04 4. 89E-Ol 

1.OOE+02 4. 78E-OS 1.70E-02 3.s8E-04 4. 93E-OI 

2.00E+02 2. 89E-Os 2.06E-02 8.94E-Os s.12E-Ol 

3.00E+02 2.22E-Os 2.3IE-02 2. 24E-OS s.17E-Ol 

4.00E+02 I. 98E-Os 2.s2E-02 s.s9E-06 S.18E-Ol 

s.OOE+02 1. 88E-Os 2.71E-02 1.40E-06 s.18E-OI 

6.00E+02 1.83E-OS 2.90E-02 3. 49E-07 S.18E-Ol 

7.00E+02 1. 79E-OS 3.08E-02 8. 73E-08 s.18E-OI ,'" 8.00E+02 1.7SE-Os 3.26E-02 2.l8E-08 s.18E-Ol 

9.00E+02 1.72E-Os 3. 43E-02 O.OOE+OO s.18E-Ol 

1.OOE+03 1. 68E-OS 3.60E-02 O.OOE+OO s.18E-Ol 

2.00E+03 1. 38E-Os s.13E-02 O.OOE+OO s.18E-OI 

4.00E+03 9. 29E-06 7.4IE-02 O.OOE+OO S.18E-OI 

8.00E+03 4.2IE-06 9.97E-02 O.OOE+OO s.18E-Ol 

1.OOE+04 2. 83E-06 I.07E-Ol O.OOE+OO s.18E-Ol 

8-266 
CLASS W AMAD = 1 MICRON STABLE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.95E-02 2. 76E-01 2. 35E-0l 5.72E-02 6.,3SE-01 

2.00E-01 6.S3E-02 2.6SE-01 1. 97E-0l 1.0SE-01 6.36E-01 

3.00E-01 6. 73E-02 2.S6E-01 1.66E-01 1.46E-01 6.34E-01 

4.00E-OI 6. 66E-02 2. 47E-OI 1. 39E..,.OI 1. 79E-OI 6.32E-OI 

S.OOE-OI 6.60E-02 2.40E-0l I.17E-OI 2.06E-01 6.29E-01 

6.00E-OI 6.S6E-02 2. 33E-OI 9.S6E-02 2.27E-01 6. 24E-01 

7.00E-01 6.S4E-02 2.27E-OI S.29E-02 2.43E-01 6.1SE-01 

S.OOE-01 6.SIE-02 2.2IE-OI 6. 97E-02 2.S4E-01 6.10E-01 

9.00E-OI 6.S0E-02 2.16E-01 5.S6E-02 2.61E-OI 6.01E-OI 

I.OOE+OO 6. 49E-02 2.11E-OI 4. 93E-02 2. 65E-OI S.90E-OI 

2.00E+OO 6. 49E-02 I.77E-0l S.72E-03 2.03E-OI 4.S4E-01 

3.00E+OO 6.S4E-02 I.60E-OI I.S4E-03 I.I3E-0l 3.40E-01 

4.00E+OO 6.5SE-02 1. SOE-OI 2. 72E-04 S.72E-02 2. 74E-OI 

5.00E+OO 6. 62E-02 I.4SE-OI 4. 82E-OS 2.SSE-02 2. 39E-OI 

6.00E+OO 6. 67E-02 I.4IE-OI S.SIE-06 1. 47E-02 2. 22E-01 

7.00E+OO 6.71E-02 1.3SE-01 1.SlE-06 S.I4E-03 2.DE-01 

8.00E+OO 6.7SE-02 I.36E-OI 2.66E-07 5.04E-03 2.0SE-OI 

9.00E+OO 6. 79E-02 1. 34E-01 4.70E-OS 3.SSE-03 2.0SE-OI 

I.OOE+OI 6.S4E-02 I.32E-OI O.OOE+OO 2.S2E-03 2.03E-OI 

2.00E+OI 7. 23E-02 I.I6E-OI O.OOE+OO I.S7E-03 I.90E-OI 

3.00E+OI 7.5SE-02 I.02E-0l O.OOE+OO 1.63E-03 I.SOE-OI 

4.00E+01 7.90E-02 9.0IE-02 O.OOE+OO I.42E-03 I.70E-OI 

S.OOE+OI S.ISE-02 7. 93E-02 O.OOE+OO I.23E-03 1.62E-OI 

6.00E+OI S.44E-02 6.9SE-02 O.OOE+OO 1.07E-03 I.5SE-OI 

7.00E+0l S.67E-02 6.14E-02 O.OOE+OO 9.36E-04 I.49E-OI 

S.OOE+01 S.SSE-02 S.40E-02 O.OOE+OO S.ISE-04 1. 44E-OI 

9.00E+OI 9.06E-02 4.7SE-02 O.OOE+OO 7.09E-04 1. 39E-OI 

I.OOE+02 9.22E-02 4. ISE-02 O.OOE+OO 6.17E-04 I.3SE-OI 

2.00E+02 1.0lE-OI 1. ISE-02 O.OOE+OO 1. S4E-04 I.I2E-0l 

3.00E+02 1.02E-OI 3. ISE-03 O.OOE+OO 3.S6E-05 I.OSE-OI 

4.00E+02 I.OIE-OI S.SSE-04 O.OOE+OO 9.6SE-06 I.02E-OI 

5.00E+02 9. 92E-02 2.3IE-04 O.OOE+OO 2.4IE-06 9. 95E-02 

6.00E+02 9. 74E-02 6.19E-OS O.OOE+OO 6.03E-07 9. 74E-02 

7.00E+02 9.SSE-02 I.6SE-OS O.OOE+OO I.SIE-07 9.5SE-02 

S.OOE+02 9.36E-02 4.40E ..... 06 O.OOE+OO 3.77E-OS 9. 36E-02 

9.00E+02 9.18E-02 I.I6E-06 O.OOE+OO O.OOE+OO 9. ISE-02 

I.OOE+03 9.00E-02 3.08E-07 O.OOE+OO O.OOE+OO 9.00E-02 

2.00E+03 7.38E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.3SE-02 

4.00E+03 4. 97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 97E-02 . S.OOE+03 4.0BE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.0BE-02 

7.00E+03 2.74E'-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 74E-02 

B.OOE+03 2.2SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.2SE-02 

I.OOE+04 1. SIE-02 O.OOE+OO O.OOE+OO O.OOE+OO I.SIE-02 

2.00E+04 2.09E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.09E-03 

B-267 
CLASS V AMAD = 1 MICRON STABLE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCmmLATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.S0E-03 8.10E-06 

2.00E-OI 2.8SE-03 1. 64E-04 

3.00E-OI 3. 89E-03 8. 29E-04 

4.00E-OI 4.67E-03 2. 42E-03 

S~OOE-OI S.27E-03 S.28E-03 

6.00E-OI S.72E-03 9.6IE-03 

7.00E-Ol 6.07E-03 1. SSE-02 

8.00E-OI 6. 33E-03 2.30E-02 

9.00E-OI 6.S3E-03 3.19E-02 

I.OOE+OO 6. 69E-03 6. 69E-03 4.2IE-02 4. 21E-02 

2. OOE+OO S.02E-04 7.19E-03 1.3SE-Ol 1.77E-Ol 

3.00E+OO 9.24E-OS 7.28E-03 1. 14E-Ol 2. 92E-Ol 

4.00E+OO 6.S6E-OS 7.3SE-03 6.6SE-02 3.S8E-Ol 

S.OOE+OO 6.33E-05 7.41E-03 3. 42E-02 3. 92E-Ol 

6. OOE+OO 6. 27E-05 7. 47E-03 1.71E-02 4.09E-Ol 

7.00E+OO 6.23E-05 7.S4E-03 8. 78E-03 4.l8E-Ol 

8.00E+OO 6. 19E-OS 7.60E-03 4.84E-03 4.23E-Ol 

9.00E+OO 6.lSE-OS 7.66E-03 2. 97E-03 4. 26E-Ol 

1.OOE+Ol 6.l1E-OS 7.72E-03 2. 07E-03 4. 28E-Ol 

2.00E+Ol S.76E-OS 8.3lE-03 I.09E-03 4.40E-Ol 

3. OOE+OI 5. 42E-05 8.B7E-03 9.44E-04 4. SlE-Ol 

4.00E+OI S.I2E-OS 9.40E-03 B.22E-04 4.S9E-Ol 

5.00E+Ol 4.B4E-05 9. 89E-03 7.1SE-04 4.67E-Ol 

6.00E+OI 4.S8E-OS 1. 04E-02 6.23E-04 4. 74E-Ol 

7.00E+Ol 4. 34E-05 1.08E-02 S.42E-04 4. 79E-Ol 

8.00E+Ol 4.l2E-OS l.l2E-02 4. 72E-04 4. 84E-Ol 

9.00E+Ol 3. 92E-OS 1. 16E-02 4.llE-04 4.B9E-Ol 

1.OOE+02 3. 74E-OS 1.20E-02 3. 58E-04 4. 93E-Ol 

2.00E+02 2. 62E-OS 1.5lE-02 8. 94E-OS 5. 12E-Ol 

3.00E+02 2.2lE-OS 1. 75E-02 2. 24E-OS S.17E-Ol 

4.00E+02 2.06E-OS 1.96E-02 S.59E-06 S.18E-OI 

S.OOE+02 1.9BE-OS 2.16E-02 1.40E-06 S • .18E-Ol 

6.00E+02 I. 93E-OS 2. 36E-02 3.49E-07 S.18E-Ol 

7.00E+02 I.B9E-OS 2.SSE-02 8.73E-OB 5.18E-Ol 

8.00E+02 I. BSE-OS 2. 74E-02 2.lBE-OB S.18E-Ol 

9.00E+02 I.B2E-OS 2. 92E-02 O.OOE+OO S.lBE-Ol 

I.OOE+03 1. 78E-OS 3.lOE-02 O. OOE+OO S.18E-Ol 

2.00E+03 I.46E-OS 4.72E-02 O.OOE+OO S.18E-Ol 

4.00E+03 9. 84E-06 7.l3E-02 O.OOE+OO S.18E-Ol 

B.OOE+03 4. 46E-06 9. BSE-02 O.OOE+OO S.18E-Ol 

1.OOE+04 3.00E-06 1. 06E-OI O.OOE+OO S.18E-Ol 

B-268 
ClASS W AMAD == 1 KICRON BALFLIFE= 9.58E+02 DAYS PROMETHIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL· GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.9SE-02 2. 76E-Ol 2.3SE-0l S.72E-02 6. 38E-Ol 

2.00E-Ol 6.B2E-02 2.6SE-Ol 1. 97E-Ol I.OSE-Ol 6.36E-Ol 

3.00E-Ol 6. 73E-02 2. S6E-Ol 1. 66E-Ol 1. 46E-Ol 6.34E-Ol 

4.00E-Ol 6.6SE-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6. 32E-Ol 

S.OOE-Ol 6.60E-02 2.40E-Ol 1.17E-0l 2.06E-Ol 6.28E-Ol 

6.00E-Ol 6.S6E-02 2.33E-Ol 9.B6E-02 2. 27E-Ol 6.24E-Ol 

7.00E-Ol 6.S3E-02 2. 26E-Ol B.29E-02 2.43E-Ol 6.17E-Ol 

8.00E-Ol 6.SlE-02 2.2lE-Ol 6. 97E-02 2.S4E-Ol 6.09E-Ol 

9.00E-0l 6.S0E-02 2.1SE-Ol S. B6E-02 2.61E-Ol 6.00E-Ol 

1.OOE+OO 6. 49E-02 2.11E-Ol 4. 93E-02 2.6SE-Ol S.90E-Ol 

2.00E+OO 6. 49E-02 1.77E-Ol B.71E-03 2.03E-Ol 4.S4E-Ol 

3.00E+OO 6.S2E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3. 39E-Ol 

4.00E+OO 6.S6E-02 1. SOE-Ol 2. 72E-04 s.71E-02 2.73E-Ol 

S.OOE+OO 6.60E-02 1.44E-OI 4. BOE-OS 2.B4E-02 2.3BE-Ol 

6.00E+OO 6. 64E-02 1.40E-Ol B.4BE-06 1.46E-02 2.2lE-OI 

7.00E+OO 6. 68E-02 1.37E-Ol 1.SOE-06 B.09E-03 2.l2E-Ol 

B.OOE+OO 6.71E-02 1.3SE-Ol 2.6SE-07 S.OIE-03 2.07E-0l 

9.00E+OO 6.7SE-02 1. 33E-Ol 4. 67E-OB 3.S2E-03 2.04E-Ol 

1.OOE+Ol 6.79E-02 1.31E-0l O.OOE+OO 2. BOE-03 2.02E-Ol 

2.00E+Ol 7.l2E-02 I.ISE-Ol O.OOE+OO 1. BSE-03 1.BBE-OI 

3.00F+Ol 7.42E-02 1.OOE-0l O.OOE+OO 1. S9E-03 1.76E-Ol 

4.00E+Ol 7. 67E-02 B.7SE-02 O.OOE+OO 1.3BE-03 1. 66E-Ol 

S.OOE+Ol 7.B9E-02 7. 64E-02 O.OOE+OO I.19E-03 1. S7E-Ol 

6.00E+Ol B.OBE-02 6.6BE-02 O.OOE+OO 1.03E-03 1. 49E-OI 

7.00E+Ol 8. 24E-02 S.B3E-02 O.OOE+OO B.90E-04 1.42E-Ol 

B.OOE+OI B.3BE-02 S.lOE-02 O.OOE+OO 7. 69E-04 1.3SE-Ol 

9.00E+Ol B.49E-02 4.4SE-02 O.OOE+OO 6. 64E-04 1.30E-Ol 

1.OOE+02 B.SBE-02 3.89E-02 O.OOE+OO S.74E-04 1.2SE-Ol 

2.00E+02 B.7lE-02 9. 97E-03 O.OOE+OO 1. 34E-04 9.72E-02 

3.00E+02 B.20E-02 2.S4E-03 O.OOE+OO 3. lIE-OS B.46E-02 

4.00E+02 7. SSE-02 6.40E-04 O.OOE+OO 7. 22E-06 7.62E-02 

S.OOE+02 6.9lE-02 1.6lE-04 O.OOE+OO 1. 68E-06 6. 93E-02 

6.00E+02 6.31E-02 4. OlE-OS O.OOE+OO 3.9lE-07 6.3lE-02 

7.00E+02 S.7SE-02 9. 96E-06 O.OOE+OO 9.0BE-OB S.7SE-02 

B.OOE+02 S.2SE-02 2. 46E..;.06 O.OOE+OO 2.11E-OB S.2SE-02 

9.00E+02 4.7BE-02 6.07E-07 O.OOE+OO O.OOE+OO 4.7BE-02 

1.OOE+03 4. 36E-02 1.49E-07 O.OOE+OO O.OOE+OO 4.36E-02 

2.00E+03 1. 74E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 74E-02 

4.00E+03 2.7SE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.7SE-03 

S.OOE+03 I.09E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-03 

7.00E+03 1.73E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1. 73E-04 

8.00E+03 6.B7E-OS O.OOE+OO O.OOE+OO O.OOE+OO 6. 87E-OS 

9.00E+03 2. 73E-OS O.OOE+OO O.OOE+OO O.OOE+OO 2.73E-OS 

1.OOE+04 I.09E-OS O.OOE+OO O.OOE+OO O.OOE+OO I.09E-OS 

B-269 
CLASS W AHA» ... 1 MICR.ON HALFLlFE- 9.58E+02 DAYS PROMETHIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NDN-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HDUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.DDE-Dl 1. SO.E-0.3 8.10.E-0.6 

2.0.0.E-0'1 2.8SE-0.3 1. 64E-0.4 

3.0.0.E-Dl 3. 89E-0.3 8.29E-0.4 

4.0.0.E-O.l 4. 67E-0.3 2. 42E-0.3 

S.O.O.E-o'l S.27E-0.3 S.28E-0.3 

6.0.0.E-O.l S.72E-0.3 9. 61E-0.3 

7.0.0.E-O.l 6.0.6E-0.3 1. SSE-0.2 

8.0.0.E-O.l 6. 33E-0.3 2.30.E-0.2 

9.0.0.E-O.l 6.S3E-0.3 3. 19E-O.2 

1.000'E+0'0' 6. 68E-0.3 6. 68E-0.3 4. 21E-0'2 4. 21E-0'2 

2. 0. O.E+ DO. S.0.IE-0.4 7. 18E-0.3 1.3SE-0'1 1. 77E-O.l 

3.0.0.E+0.0. 9. 22E-O.S 7. 27E-0.3 1. 14E-O.l 2. 91E-O.l 

4.0.0.E+0.0. 6.S4E-O.S 7. 33E-0.3 6.63E-0.2 3. S7E-O.l 

S.O.O.E+O.O. 6.31E-O.S 7. 39E-0.3 3.40.E-0.2 3. 91E-O.l 

6. 0. DE +0.0. 6. 24E-O.S 7. 44E-0.3 1.70.E-0'2 4.D8E-O.l 

7.O.DE+DO. 6. 19E-O.S 7.SO.E-0.3 8.73E-0.3 4. 16E-O.l 

8.0.0.E+0'0. 6.1SE-O.S 7.SSE-0.3 4. 81E-0.3 4. 21E-O.l 

9.0'0'E+0'0' 6. 11E-O.S 7. 61E-0.3 2.9SE-0.3 4. 23E-O.l 

1.000.E+O.l 6.0.7E-O.S 7. 67E-0.3 2.O.SE-0.3 4.2SE-0'1 

2.0.0.E+0'1 S.67E-O.S 8. 19E-0.3 1.0.7E-0.3 4. 34E-O.l 

3.0.0.E+O.l S.31E-O.S 8. 68E-0.3 9. 24E-0'4 4. 41E-O.l 

4.0.0.E+0'1 4. 97E-O.S 9. 13E-0.3 7. 98E-0.4 4. 46E-O.l 

S.O.o'E+Dl 4. 66E-O.S 9.S4E-0.3 6.90.E-0.4 4. SO.E-O.l 

6.0.0.E+O.l 4. 38E-O.S 9. 92E-D3 S.96E-0'4 4.5-3E-0'1 

7.0.0.E+0'1 4. 12E-o'S 1.0.3E-0'2 5. 15E-04 4.56E-O.l 

8.0.0.E+O.l 3. 89E-O.S 1.0.6E-0.2 4.4SE-0.4 4. 57E-O.l 

9.0'0'E+O.l 3. 67E-O.S 1.0.9E-0.2 3.85E-04 4.S8E-0'1 

I.O.O.E+0.2 3. 48E-0.5 1. 12E-0'2 3. 33E-0.4 4.S8E-0'1 

2.0'0'E+0.2 2. 27E-0.5 1. 31E-0.2 7.74E-O.S 4. 43E-O.l 

3.0'0'E+02 1. 78E-O.S 1.41E-0'2 1.80.E-O.S 4. 16E-O.l 

4.0.0.E+0.2 1. 54E-O.S 1.47E-0'2 4. 18E-0.6 3. 88E-O.l 

5.0.0.E+0.2 1. 38E-O.S I.SO.E-0.2 9. 73E-0.7 3. 61E-O.l 

6.0.0.E+0.2 1.2SE-0.5 I.S3E-0.2 2.26E-0.7 3. 36E-O.l 

7.0'0'E+0.2 1. 14E-0.5 1. 54E-0.2 5. 26E-0.8 3. 12E-O.l 

8.0.0.E+0.2 1.0'4E-0.5 1. 53E-0.2 1. 22E-0.8 2.90'E-0'1 

9.0.0.E+0.2 9. 48E-0.6 1. 52E-0.2 o'.o'o'E+o'o' 2.70.E-0'1 

1.0.0.E+0.3 8. 64E-0.6 1.50.E-0.2 D. O.O.E + DO. 2. 51E-O.l 

2.0.0.E+0.3 3. 44E-0.6 1. 11E-0.2 D. O.O.E +0. 0. 1. 22E-O.l 

4.0'0'E+0.3 5. 44E-0.7 3. 94E-0.3 o'.o'o'E+oo 2. 86E-0.2 

5.0'0'E+0.3 2. 16E-0.7 2. 15E-0.3 O..O.O.E+o'o' 1. 39E-0.2 

7.0.0.E+0.3 3. 42E-0.8 5. 89E-0.4 o'.o'o'E+o'o' 3.26E-0.3 

B-270. 
CLASS W AHAD = 1 .MICRON BALFLIFE= 3.87E+13 DAYS SAMARIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 95E-02 2.76E-01 2. 35E-01 5.72E-02 6. 38E-01 

2.00E-01 6. 83E-02 2. 65E-01 1. 97E-01 1.05E-01 6. 36E-01 

3.00E-01 6. 73E-02 2. 56E-01 1.66E-01 1. 46E-01 6. 34E-01 

4.00E-01 6. 66E-02 2.47E-01 1. 39E-01 1. 79E-01 6. 32E-01 

5.00E-01 6.60E-02 2.40E-01 1. 17E-01 2.06E-01 6.29E-01 

6.00E-01 6. 56E-02 2. 33E-01 9. 86E-02 2.27E-01 6.24E-01 

7.00E-01 6. 54E-02 2.27E-01 8.29E-02 2. 43E-01 6. 18E-01 

8.00E-01 6.51E-02 2.21E-01 6.97E-02 2. 54E-01 6.1OE-01 

9.00E-01 6.50E-02 2. 16E-01 5. 86E-02 2.61E-01 6.01E-01 

1.00E+00 6.49E-02 2. 11E-01 4. 93E-02 2. 65E-01 5.90E-01 

2.00E+00 6. 49E-02 1.77E-01 8.72E-03 2.03E-01 4. 54E-01 

3.00E+00 6. 54E-02 1.60E-01 1. 54E-03 1. 13E-01 3.40E-01 

4.00E+00 6. 58E-02 1.50E-01 2. 72E-04 5.72E-02 2. 74E-01 

5.00E+00 6. 62E-02 1. 45E-01 4. 82E-05 2. 85E-02 2. 39E-01 

6~OE+00 6.67E-02 1.41E-01 8. 51E-06 1.47E-02 2.22E-01 

7.00E+00 6.71E-02 1.38E-01 1.51E-06 8. 14E-03 2. 13E-01 

8.00E+00 6. 75E-02 1.36E-01 2. 66E-07 5.04E-03 2.08E-01 

9.00E+00 6.79E-02 1. 34E-01 4.70E-08 3. 55E-03 2.05E-01 

1.00E+01 6. 84E-02 1.32E-01 O.OOE+OO 2. 82E-03 2.03E-01 

2.00E+01 7. 23E-02 1. 16E-01 O.OOE+OO 1. 87E-03 1.90E-01 

3.00E+01 7. 58E-02 1.02E-01 O.OOE+OO 1. 63E-03 1.80E-01 

4.00E+01 7.90E-02 9.01E-02 O.OOE+OO 1.42E-03 1.70E-01 

5.00E+01 8. 18E-02 7. 93E-02 O.OOE+OO 1.23E-03 1.62E-01 

6.00E+01 8.44E-02 6. 98E-02 O.OOE+OO 1.07E-03 1. 55E-01 

7.00E+01 8. 67E-02 6. 14E-02 O.OOE+OO 9. 36E-04 1. 49E-01 

8.00E+01 8. 88E-02 5.40E-02 O.OOE+OO 8. 15E-04 1. 44E-01 

9.00E+01 9.06E-02 4.75E-02 O.OOE+OO 7.09E-04 1. 39E-01 

1.00E+02 9. 22E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1. 35E-01 

2.00E+02 1.01E-01 1. 15E-02 O.OOE+OO 1.54E-04 1. 12E-01 

3.00E+02 1.02E-01 3. 15E-03 O.OOE+OO 3. 86E-05 1.05E-01 

4.00E+02 1.01E-01 8. 55E-04 O.OOE+OO 9.65E-06 1.02E-01 

5.00E+02 9. 92E-02 2.31E-04 O.OOE+OO 2.41E-06 9. 95E-02 

6.00E+02 9. 74E-02 6. 19E-05 O.OOE+OO 6.03E-07 9.74E-02 

7.00E+02 9.55E-02 1. 65E-05 O.OOE+OO 1. 51E-07 9. 55E-02 

8.00E+02 9.36E-02 4.40E-06 O.OOE+OO 3.77E-08 9. 36E-02 

9.00E+02 9.18E-02 1. 16E-06 O.OOE+OO O.OOE+OO 9. 18E-02 . ~ :- .. 1.00E+03 9.00E-02 3.08E-07 O.OOE+OO O.OOE+oo 9.00E-02 

2.00E+03 7. 38E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 38E-02 

4.00E+03 4.97E-02 O.OOE+OO O.OOE+OO O.OOE+oo 4. 97E-02 

5.00E+03 4.08E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.08E-02 

7.00E+03 2. 74E-02 O.OOE+OO O.OOE+OO O.OOE+oo 2.74E-02 

8.00E+03 2.25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 25E-02 

1.00E+04 1.51E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.51E-02 

2.00E+04 2.09E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.09E-03 

B-271 
CLASS W AKAD = 1 MICRON HALFLIFE= 3.87E+13 DAYS SAMARIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

,. 1.OOE-Ol 1.50E-03 8.l0E-06 

2.00E-Ol 2. 85E-03 1. 64E-04 

3.00E-Ol 3.89E-03 8. 29E-04 

4.00E-Ol 4. 67E-03 2. 42E-03 

S.OOE-Ol S.27E-03 S.28E-03 

6.00E-Ol S.72E-03 9.6lE-03 

7.00E-Ol 6.07E-03 1.5SE-02 

8.00E-Ol 6. 33E-03 2.30E-02 

9.00E-Ol 6. 53E-03 3.l9E-02 

1.OOE+OO 6. 69E-03 6.69E-03 4.2lE-02 4.2lE-02 

2.00E+OO S.02E-04 7.l9E-03 1.3SE-Ol 1.77E-Ol 

3.00E+OO 9. 24E-OS 7.28E-03 1.14E-Ol 2. 92E-Ol 

4.00E+OO 6. S6E-OS 7.35E-03 6.6SE-02 3.S8E-Ol 

S.OOE+OO 6. 33E-05 7.4lE-03 3. 42E-02 3.92E-Ol 

6.00E+OO 6.27E-OS 7.47E-03 1.7lE-02 4.09E-Ol 

7.00E+OO 6.23E-OS 7. 54E-03 8. 78E-03 4.l8E-Ol 

8.00E+OO 6.l9E-OS 7.60E-03 4.84E-03 4.23E-Ol 

9.00E+OO 6.lSE-05 7. 66E-03 2. 97E-03 4. 26E-Ol 

1.OOE+Ol 6.11E-05 7. 72E-03 2.07E-03 4.28E-Ol 

2.00E+Ol 5. 76E-OS 8.31E-03 1.09E-03 4.40E-Ol 

3.00E+Ol 5. 42E-05 8. 87E-03 9.44E-04 4.SlE-Ol 

4.00E+Ol S.12E-05 9.40E-03 B.22E-04 4.S9E-Ol 

5.00E+Ol 4. 84E-OS 9.89E-03 7.lSE-04 4.67E-Ol 

6.00E+Ol 4.S8E-OS 1.04E-02 6. 23E-04 4.74E7<}1 

7.00E+Ol 4. 34E-05 1.08E-02 S.42E-04 4. 79E-Ol 

B.OOE+Ol 4.l2E-OS 1.12E-02 4. 72E-04 4.84E-Ol 

9.00E+Ol 3. 92E-OS 1.16E-02 4.11E-04 4. 89E-Ol 

1.OOE+02 3. 74E-05 1.20E-02 3.SBE-04 4. 93E-Ol 

2.00E+02 2.62E-OS 1.SlE-02 8. 94E-OS S.12E-Ol 

3.00E+02 2.2lE-OS 1.75E-02 2. 24E-05 5.l7E-Ol 

4.00E+02 2.06E-OS 1.96E-02 S.S9E-06 S.18E-Ol 

5.00E+02 1.9BE-05 2.l6E-02 1.40E-06 S.lBE-Ol 

6.00E+02 1.93E-OS 2. 36E-02 3. 49E-07 S.18E-Ol 

7.00E+02 1. 89E-OS 2. 55E-02 8. 73E-08 S.18E-Ol 

8.00E+02 1.8SE-OS 2. 74E-02 2.lBE-08 5.18E-Ol 

9.00E+02 1. 82E-OS 2. 92E-02 O.OOE+OO S.18E-Ol 

1.OOE+03 1.7BE-OS 3.10E-02 O.OOE+OO S.18E-Ol 

2.00E+03 1. 46E-OS 4. 72E-02 O.OOE+OO S.18E-Ol 

4.00E+03 9. 84E-06 7.13E-02 O.OOE+OO S.18E-Ol 

8.00E+03 4. 46E-06 9.8SE-02 O.OOE+OO 5.lBE-Ol 

1.OOE+04 3.00E-06 1.06E-Ol O.OOE+OO S.18E-Ol 

B-272 
CLASS W AHA» = 1 MICRON STABLE SAMAR.IUH 150 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 95E-02 2. 76E-Ol 2.35E-Ol S.72E-02 6.38E-Ol 

2.00E-Ol 6. 83E-02 2.6SE-Ol 1.97E-Ol 1.05E-Ol 6.36E-Ol 

3.00E-Ol 6. 73E-02 2. 56E-Ol 1. 66E-Ol 1.46E-Ol 6.34E-Ol 

4.00E-Ol 6. 66E-02 2. 47E-Ol 1.39E-Ol 1.79E-Ol 6. 32E-Ol 

5.00E-Ol 6.60E-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6.29E-Ol 

6.00E-Ol 6. 56E-02 2. 33E-Ol 9.S6E-02 2.27E-Ol 6. 24E-Ol 

7.00E-Ol 6. 54E-02 2.27E-Ol S.29E-02 2.43E-Ol 6. ISE-Ol 

S.OOE-OI 6.5IE-02 2.21E-OI 6. 97E-02 2. 54E-Ol 6.lOE-Ol 

9.00E-Ol 6.50E-02 2.I6E-Ol 5. S6E-02 2.6IE-0l 6.0lE-Ol 

l.OOE+OO 6. 49E-02 2. HE-Ol 4. 93E-02 2. 65E-Ol 5.90E-Ol 

2.00E+OO 6. 49E-02 1.77E-Ol S.72E-03 2.03E-Ol 4.54E-Ol 

3.00E+OO 6. 54E-02 1.60E-Ol 1. 54E-03 1. 13E-Ol 3.40E-Ol 

4.00E+OO 6.SBE-02 1.50E-Ol 2. 72E-04 S.72E-02 2. 74E-Ol 

S.OOE+OO 6.62E-02 1.45E-Ol 4.B2E-OS 2.B5E-02 2. 39E-Ol 

6.00E+OO 6. 67E-02 I.41E-OI B.51E-06 1.47E-02 2.22E-Ol 

7.00E+OO 6.71E-02 1.3BE-Ol 1.51E-06 B.14E-03 2.13E-Ol 

B.OOE+OO 6. 75E-02 1. 36E-Ol 2. 66E-07 5.04E-03 2.0SE-Ol 

9.00E+OO 6. 79E-02 1. 34E-Ol 4.70E-OB 3. S5E-03 2.05E-Ol 

1.OOE+Ol 6.S4E-02 1.32E-Ol O.OOE+OO 2.S2E-03 2.03E-Ol 

2.00E+Ol 7.23E-02 1.16E-Ol O.OOE+OO 1.B7E-03 1.90E-Ol 

3.00E+Ol 7.SBE-02 1.02E-Ol O.OOE+OO 1.63E-03 1.SOE-Ol 

4.0QE+Ol 7.90E-02 9.01E-02 O.OOE+OO 1. 42E-03 1.70E-Ol 

S.OOE+Ol S.lSE-02 7.93E-02 O.OOE+OO 1. 23E-03 1.62E-OI 

6.00E+Ol S.44E-02 6.9SE-02 O.OOE+OO 1.07E-03 1.SSE-Ol 

7.00E+Ol S.67E-02 6.14E-02 O.OOE+OO 9.36E-04 1.49E-Ol 

e.OOE+Ol S.SBE-02 5.40E-02 O.OOE+OO B.lSE-04 1.44E-Ol 

9.00E+Ol 9.06E-02 4. 75E-02 O.OOE+OO 7.09E-04 1.39E-OI 

1.OOE+02 9.22E-02 4. 18E-02 O.OOE+OO 6.17E-04 1. 35E-Ol 

2.00E+02 1.OlE-Ol 1.lSE-02 O.OOE+OO I.S4E-04 1.12E-Ol 

3.00E+02 1.02E-OI 3.1SE-03 O.OOE+OO 3.B6E-OS 1.OSE-Ol 

4.00E+02 1.OlE-OI B. SSE-04 O.OOE+OO 9.65E-06 1.02E-0l 

5.00E+02 9. 92E-02 2.31E-04 O.OOE+OO 2.41E-06 9. 95E-02 

6.00E+02 9. 74E-02 6. 19E-OS O.OOE+OO 6.03E-07 9.74E-02 

7.00E+02 9.SSE-02 1. 65E-OS O.OOE+OO 1.SIE-07 9.SSE-02 

B.OOE+02 9. 36E-02 4.40E"'06 O.OOE+OO 3.77E-OB 9.36E-02 

9.00E+02 9.1BE-02 1.16E-06 O.OOE+OO O.OOE+OO 9.1SE-02 .. 1.OOE+03 9.00E;"02 3.0SE-07 O.OOE+OO O.OOE+OO 9.00E-02 

2.00E+03 7.3SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.3SE-02 

4.00E+03 4. 97E-02 O.OOE+OO O.OOE+OO OoOOE+OO 4.97E-02 

5.00E+03 4.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.0BE-02 

7.00E+03 2. 74E-02 O.OOE+OO O.OOE+OO O.OOE+OO 20 74E-02 

S.OOE+03 2.25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 25E-02 ~.OOE+04 lo51E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.SlE-02 

2.00E+04 2009E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.09E-03 

B-273 
CLASS W AMA.D = 1 MICRON STABLE SAMARIUM 150 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.50E-03 8.1OE-06 

2.00E-Ol 2. 85E-03 1.64E-04 

3.00E-01 3. 89E-03 8.29E-04 

4.00E-01 4. 67E-03 2. 42E-03 

5.00E-01 5. 27E-03 5. 28E-03 

6.00E-01 5. 72E-03 9.61E-03 

7.00E-01 6.07E-03 1.55E-02 

8.00E-Ol 6. 33E-03 2.30E-02 

9.00E-01 6. 53E-03 3. 19E-02 

1.00E+00 6. 69E-03 6. 69E-03 4.21E-02 4.21E-02 

2.00E+00 5.02E-04 7.19E-03 1.35E-Ol 1.77E-Ol 

3.00E+00 9. 24E-05 7. 28E-03 1.14E-01 2. 92E-01 

4.00E+00 6.56E-05 7.35E-03 6.65E-02 3.58E-01 

5.00E+00 6. 33E-05 7.41E-03 3.42E-02 3. 92E-01 

6.00E+00 6. 27E-05 7.47E-03 1.71E-02 4.09E-01 

7.00E+00 6.23E-05 7. 54E-03 8. 78E-03 4. 18E-0 1 

8.00E+00 6. 19E-05 7.60E-03 4.84E-03 4.23E-01 

9.00E+00 6. 15E-05 7. 66E-03 2.97E-03 4. 26E-01 

1.0oE+01 6. 11E-05 7.72E-03 2.07E-03 4.28E-01 

2.00E+01 5. 76E-05 8.31E-03 1.09E-03 4.40E-01 

3.0oE+01 5.42E-05 8. 87E-03 9.44E-04 4.51E-01 

4.00E+01 5. 12E-05 9.4oE-03 8.22E-04 4.59E-01 

5.00E+01 4.84E-05 9.89E-03 7.15E-04 4.67E-Ol 

6.00E+Ol 4. 58E-05 1.o4E-02 6.23E-04 4. 74E-01 

7.00E+01 4. 34E-05 1.08E-02 5.42E-04 4.79E-01 

8.00E+ol 4. 12E-05 1. 12E-02 4.72E-04 4. 84E-01 

9.00E+01 3. 92E-05 1. 16E-02 4. 11E-04 4. 89E-01 

1.00E+02 3. 74E-05 1.20E-02 3. 58E-04 4. 93E-01 

2.0oE+02 2. 62E-05 1.51E-02 8.94E-05 5.12E-ol 

3.00E+02 2.21E-05 1. 75E-02 2. 24E-05 5.17E-01 

4.0oE+02 2.06E-05 1.96E-02 5. 59E-06 5.18E-Ol 

5.00E+02 1. 98E-05 2. 16E-02 1.40E-06 5. 18E-01 

6.00E+02 1. 93E-05 2. 36E-02 3. 49E-07 5. 18E-01 

7.00E+02 1. 89E-05 2. 55E-02 8. 73E-08 5. 18E-01 

8.00E+02 1.85E-05 2. 74E-02 2. 18E-08 5. 18E-01 

9.00E+02 1.82E-05 2. 92E-02 O.OOE+OO 5. 18E-01 

1.00E+03 1. 78E-05 3.lOE-02 O.OOE+oo 5. 18E-01 

2.00E+03 1.46E-05 4.72E-02 O.OOE+OO 5. 18E-01 

4.00E+03 9. 84E-06 7. 13E-02 O.OOE+oo 5.18E-Ol 

8.00E+03 4. 46E-06 9. 85E-02 O.OOE+Oo 5. 18E-Ol 

1.00E+04 3.0oE-06 1.06E-Ol O.OOE+OO 5. 18E-01 

B-274 
CLASS W AKAD ::::: 1 MICRON STABLE EUROPIUM 151 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.89E-02 2. 76E-01 2.35E-Ol 5.72E-02 6.37E-Ol 

2.00E-Ol 6. 71E-02 2.65E-01 1.97E-Ol 1.05E-Ol 6. 35E-Ol 

3.00E-Ol 6.57E-02 2.56E-01 1.66E-01 1.45E-01 6.33E-01 

4.00E-01 6. 47E-02 2.47E-Ol 1. 39E-01 1.79E-Ol 6.30E-01 

5.00E-01 6.39E-02 2.40E-Ol 1. 17E-Ol 2.06E-01 6.26E-Ol 

6.00E-01 6.33E-02 2. 33E-01 9. 86E-02 2. 27E-01 6.21E-01 

7.00E-01 6. 29E-02 2. 27E-Ol 8.29E-02 2.43E-01 6.15E-Ol 

8.00E-01 6. 25E-02 2. 21E-01 6. 97E-02 2. 54E-Ol 6.07E-Ol 

9.00E-Ol 6. 23E-02 2.16E-01 5. 86E-02 2.61E-01 5.98E-01 

1.00E+00 6.21E-02 2.llE-01 4. 93E-02 2. 65E-Ol 5.87E-01 

2.00E+00 6. 18E-02 1. 77E-01 8. 72E-03 2.03E-Ol 4.51E-01 

3.00E+00 6. 19E-02 1.60E-Ol 1.54E-03 1. 13E-Ol 3. 37E-Ol 

4.00E+00 6. 21E-02 1.50E-Ol 2.72E-04 5.72E-02 2.70E-Ol 

5.00E+00 6. 23E-02 1.45E-Ol 4. 82E-05 2. 85E-02 2.35E-Ol 

6.00E+00 6.25E-02 1.41E-Ol 8.51E-06 1.47E-02 2. 18E-Ol 

7.00E+00 6. 27E-02 1. 38E-01 1. 51E-06 8. 13E-03 2.09E-Ol 

8.00E+00 6. 29E-02 1.36E-01 2.66E-07 5.03E-03 2.04E-Ol 

9.00E+00 6.31E-02 1. 34E-01 4.70E-08 3.54E-03 2.01E-01 

1.00E+Ol 6. 34E-02 1.32E-Ol O.OOE+OO 2.81E-03 1.98E-01 

2.00E+Ol 6. 59E-02 1. 16E-Ol O.OOE+OO 1. 87E-03 1.84E-Ol 

3.00E+01 6.85E-02 1.02E-Ol O.OOE+OO 1. 63E-03 1.72E-Ol 

4.00E+01 7.11E-02 9.01E-02 O.OOE+OO 1. 42E-03 1.63E-Ol 

5.00E+01 7. 35E-02 7.93E-02 O.OOE+OO 1.23E-03 1.54E-01 

6.00E+01 7.56E-02 6. 98E.-02 O.OOE+OO 1.07E-03 1.46E-01 

7.00E+Ol 7. 76E-02 6. 14E-02 O.OOE+OO 9. 35E-04 1.40E-01 

8.00E+01 7. 94E-02 5.40E-02 O.OOE+OO 8. 14E-04 1.34E-01 

9.00E+Ol 8.10E-02 4. 75E-02 O.OOE+OO 7.09E-04 1.29E-Ol 

1.00E+02 8.24E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1.25E-Ol 

2.00E+02 8. 98E-02 1.15E-02 O.OOE+OO 1.54E-04 1.01E-01 

3.00E+02 9.09E-02 3. 15E-03 O.OOE+OO 3. 86E-05 9.41E-02 

4.00E+02 9.00E-02 8.55E-04 O.OOE+OO 9.64E-06 9.08E-02 

5.00E+02 8.85E-02 2.31E-04 O.OOE+OO 2.41E-06 8.87E-02 

6.00E+02 8. 68E-02 6. 19E-05 O.OOE+OO 6.03E-07 8. 69E-02 

7.00E+02 8.51E-02 1. 65E-05 O.OOE+OO 1.51E-07 8. 52E-02 

8.00E+02 8.35E-02 4.40E-06 O.OOE+OO 3. 77E-08 8. 35E-02 

9.00E+02 8. 18E-02 1. 16E-06 O.OOE+OO O.OOE+OO 8. 18E-02 

1.00E+03 8.02E-02 3.08E-07 O.OOE+OO O.OOE+OO 8.02E-02 

2.00E+03 6. 58E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 58E-02 

4.00E+03 4.43E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.43E-02 

5.00E+03 3. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 63E-02 

7.00E+03 2. 45E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.45E-02 

8.00E+03 2.01E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.01E-02 

1.00E+04 1. 35E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.35E~02 

2.00E+04 1. 86E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.86E-03 

B-275 
CLASS W AMAD = 1 MICRON STABLE EUROPIUM 151 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.12E-03 8.10E-06 

2.00E-Ol 4.0SE-03 1. 64E-04 

3.00E-Ol S.S3E-03 8. 29E-04 

4.00E-Ol 6.6SE-03 2. 42E-03 

S.OOE-Ol 7.S2E-03 S.28E-03 

6.00E-Ol 8.19E-03 9.61E-03 

7.00E-Ol 8.70E-03 1.SSE-02 

8.00E-Ol 9.10E-03 2.30E-02 

9.00E-Ol 9.41E-03 3.l9E-02 

1.OOE+OO 9. 66E-03 9. 66E-03 4.2lE-02 4.21E-02 

2.00E+OO 9.82E-04 1.06E-02 1.3SE-Ol 1.77E-Ol 

3.00E+.OO 3. 83E-04 lAlOE-02 1.14E-Ol 2. 92E-Ol 

4.00E+OO 3. 27E-04 1.14E-02 6. 64E-02 3.S8E-Ol 

S.OOE+OO 3.09E-04 1.17E-02 3.41E-02 3. 92E-Ol 

6.00E+OO 2. 94E-04 1.20E-02 1.71E-02 4.09E-Ol 

7.00E+OO 2.81E-04 1. 22E-02 8.77E-03 4.18E-Ol 

8.00E+OO 2.69E-04 1.2SE-02 4.83E-03 4.23E-Ol 

9.00E+OO 2.S8E-04 1. 28E-02 2. 96E-03 4. 26E-Ol 

1.OOE+Ol 2.47E-04 1.30E-02 2.07E-03 4. 28E-Ol 

2.00E+Ol 1.7lE-04 1.SOE-02 1.08E-03 4.40E-Ol 

3.00E+Ol 1.30E-04 1.6SE-02 9.43E-04 4.S0E-Ol 

4.00E+Ol 1.06E-04 1. 76E-02 8.21E-04 4.S9E-Ol 

S.OOE+Ol 9.0SE-OS 1.86E-02 7.1SE-04 4.67E-Ol 

6.00E+Ol 8.02E-OS 1.9SE-02 6.22E-04 4. 73E-Ol 

7.00E+Ol 7.26E-OS 2.02E-02 S.42E-04 4. 79E-Ol 

8.00E+Ol 6.6SE-OS 2.09E-02 4.72E-04 4.84E-Ol 

9.00E+Ol 6. l3E-OS 2.1SE-02 4.11E-04 4.88E-Ol 

1.OOE+02 S.68E-OS 2.21E-02 3.S7E-04 4. 92E-Ol 

2.00E+02 3.11E-OS 2. 63E-02 8. 94E-OS S.llE-Ol 

3.00E+02 2.2lE-OS 2. 89E-02 2. 23E-OS S.16E-Ol 

4.00E+02 1.91E-OS 3.09E-02 S.S9E-06 S.17E-0l 

S.OOE+02 1. 79E-OS 3. 27E-02 1.40E-06 S.18E-Ol 

6.00E+02 1.73E-OS 3.4SE-02 3. 49E-07 S.18E-Ol 

7.00E+02 1. 69E-OS 3. 62E-02 8. 73E-08 S.18E-Ol 

8.00E+02 1.6SE-OS 3. 79E-02 2.l8E-08 S.18E-Ol 

9.00E+02 1. 62E-OS 3.9SE-02 O.OOE+OO S.18E-Ol 

1.OOE+03 1. S9E-OS 4.11E-02 O.OOE+OO S.18E-Ol 

2.00E+03 1.30E-OS S.SSE-02 O.OOE+OO S.18E-Ol 

4.00E+03 8.77E-06 7.70E-02 O.OOE+OO S.18E-Ol 

8.00E+03 3. 97E-06 1.OlE-Ol O.OOE+OO S.18E-Ol 

1.OOE+04 2. 67E-06 1.08E-Ol O.OOE+OO S.18E-Ol 

B-276 
CLASS W .AHAD == 1 MICRON BAULIFE= 4.87£+03 DAYS EUROPIUM 152 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 89E-02 2.76E-01 2.35E-01 5.72E-02 6.37E-01 

2.00E-01 6.71E-02 2. 65E-01 1.97E-01 1.05E-01 6. 35E-01 

3.00E-01 6. 57E-02 2.56E-01 1.66E-01 1.45E-01 6. 33E-01 

4.00E-01 6.47E-02 2. 47E-01 1. 39E-01 1. 79E-01 6.30E-01 

5.DOE-01 6. 39E-02 2.40E-Ol 1. 17E-01 2.06E-01 6.26E-01 

6.00E-01 6. 33E-02 2. 33E-01 9. 86E-02 2. 27E-01 6. 21E-01 

7.00E-01 6. 29E-02 2. 27E-01 8. 29E-02 2. 43E-Ol 6. 15E-01 

8.00E-01 6. 25E-02 2.21E-01 6. 97E-02 2. 54E-Ol 6.07E-01 

9.00E-01 6. 23E-02 2. 16E-01 5. 86E-02 2.61E-01 5.98E-01 

1.00E+00 6.21E-02 2. 11E-01 4. 93E-02 2. 65E-01 5.87E-01 

2.00E+00 6. 17E-02 1.77E-01 8.72E-03 2.03E-01 4.51E-01 

3.00E+00 6. 19E-02 1.60E-01 1. 54E-03 1. 13E-01 3. 36E-01 

4.00E+00 6.21E-02 1.50E-01 2.72E-04 5.71E-02 2.70E-01 

5.00E+00 ' 6. 22E-02 1. 44E-01 4. 81E-05 2. 84E-02 2. 35E-01 

6.00E+00 6. 24E-02 1.41E-01 8.5lE-06 1.46E-02 2. 18E-01 

7.00E+DO 6. 26E-02 1. 38E-01 1.50E-06 8. 12E-03 2.09E-01 

8.00E+00 6.28E-02 1. 36E-01 2. 66E-07 5.03E-03 2.04E-01 

9.00E+00 6.31E-02 1. 34E-01 4.70E-08 3. 54E-03 2.00E-01 

1.00E+01 6. 33E-02 1. 32E-01 O.OOE+OO 2.81E-03 1.98E-01 

2.00E+01 6. 57E-02 1.16E-01 O.OOE+OO 1. 87E-03 1. 83E-01 

3.00E+01 6. 82E-02 1.02E-01 O.OOE+OO 1.62E-03 1.72E-01 

4.00E+01 7.07E-02 8. 95E-02 O.OOE+OO 1.41E-03 1. 62E-01 

5.00E+01 7.29E-02 7.87E-02 O.OOE+OO 1.23E-03 1. 53E-01 

6.00E+01 7.50E-02 6. 92E-02 O.OOE+OO 1.07E-03 1.45E-01 

7.00E+01 7. 69E-02 6.08E-02 O.OOE+OO 9. 26E-04 1.39E-01 

8.00E+01 7.85E-02 5. 34E-02 O.OOE+OO 8.05E-04 1. 33E-01 

9.00E+01 8.00E-02 4.69E-02 O.OOE+OO 7.00E-04 1. 28E-01 

1.00E+02 8. 13E-02 4. 12E-02 O.OOE+OO 6.08E-04 1.23E-01 

2.00E+02 8.73E-02 1. 12E-02 O.OOE+OO 1.50E-04 9. 86E-02 

3.00E+02 8.71E-02 3.02E-03 O.OOE+OO 3. 69E-05 9.01E-02 

4.00E+02 8.50E-02 8.08E-04 O.OOE+OO 9. 11E-06 8.58E-02 

5.00E+02 8. 24E-02 2. 15E-04 O.OOE+OO 2. 24E-06 8.26E-02 

6.00E+02 7. 97E-02 5.68E-05 O.OOE+OO 5. 53E-07 7. 98E-02 

7.00E+02 7.71E-02 1.50E-05 O.OOE+OO 1.36E-07 7.71E-02 

8.00E+02 7.45E-02 3. 92E-06 O.OOE+OO 3. 36E-08 7.45E-02 

9.00E+02 7.20E-02 1.02E-06 O.OOE+OO O.OOE+OO 7.20E-02 

1.00E+03 6. 96E-02 2.67E-07 O.OOE+OO O.OOE+OO 6. 96E-02 

2.00E+03 4. 95E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 95E-02 

4.00E+03 2. 51E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.51E-02 

5.00E+03 1. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 78E-02 

7.00E+03 9.02E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.02E-03 

8.00E+03 6.42E-03 O.OOE+OO O.OOE+OO O.OOE+OO 6. 42E-03 

1.00E+04 3.25E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3. 25E-03 

2.00E+04 1.08E-04 O.OOE+OO O.OOE+OO O.OOE+OO 1.08E-04 

B-277 
CLASS V AHA» = 1 MICltON HALFLIPE- 4.87E+03 DAYS EUROPIUM 152 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 2.12E-03 S.lOE-06 

2.00E-Ol 4.0SE-03 1. 64E-04 

3.00E-Ol S.S3E-03 S.29E-04 

4.00E-Ol 6.6SE-03 2.42E-03 

S.OOE-Ol 7.S2E-03 S.2SE-03 

6.00E-Ol S.lSE-03 9.61E-03 

7.00E-Ol S.70E-03 1. SSE-02 

S.OOE-Ol 9.l0E-03 2.30E-02 

9.00E-Ol 9.41E-03 3.l9E-02 

1.OOE+OO 9. 66E-03 9. 66E-03 4.2lE-02 4.21E-02 

2.00E+OO 9.S2E-04 1.06E-02 1.3SE-Ol 1.77E-Ol 

3.00E+OO 3.S2E-04 1.lOE-02 I.l4E-Ol 2.9lE-Ol 

4.00E+OO 3. 27E-04 1.13E-02 6.64E-02 3.SSE-Ol 

S.OOE+OO 3.0SE-04 1.l7E-02 3.4lE-02 3. 92E-Ol 

6.00E+OO 2. 94E-04 1.19E-02 I.71E-02 4.09E-OI 

7.00E+OO 2.S1E-04 1. 22E-02 S.76E-03 4.lSE-Ol 

S.OOE+OO 2.69E-04 l.2SE-02 4. S3E-03 4. 22E-Ol 

9.00E+OO 2.S7E-04 1.27E-02 2. 96E-03 4.2SE-Ol 

1.OOE+Ol 2. 47E-04 1.30E-02 2.06E-03 4.27E-OI 

2.00E+Ol 1.71E-04 1.SOE-02 1.OSE-03 4. 39E-Ol 

3.00E+Ol 1. 29E-04 1.64E-02 9.39E-04 4.4SE-Ol 

4.00E+Ol 1.OSE-04 1.7SE-02 S.l7E-04 4. 56E-Ol 

S.OOE+Ol S.99E-OS 1.SSE-02 7.lOE-04 4.63E-Ol 

6.00E+Ol 7.9SE-OS 1. 93E-02 6.17E-04 4. 69E-Ol 

7.00E+Ol 7.l9E-05 2.00E-02 S.36E-04 4. 74E':"'Ol 

S.OOE+Ol 6.S7E-OS 2.07E-02 4. 66E-04 4. 79E-Ol 

9.00E+0l 6.0SE-OS 2.l3E-02 4.0SE-04 4.S2E-Ol 

1.OOE+02 S.60E-OS 2.1SE-02 3.S2E-04 4.SSE-Ol 

2.00E+02 3.02E-OS 2.SSE-02 S.69E-OS 4.97E-Ol 

3.00E+02 2.l2E-05 2.77E-02 2.l4E-05 4.9SE-Ol 

4.00E+02 1.80E-05 2.92E-02 S.2SE-06 4.89E-Ol 

5.00E+02 1.67E-OS 3.0SE-02 1.30E-06 4.S2E-Ol 

6.00E+02 1. 59E-OS 3. 17E-02 3.20E-07 4. 75E-Ol 

7.00E+02 1.S3E-OS 3.2SE-02 7.90E-OS 4. 69E-Ol 

S.OOE+02 1.48E-OS 3. 38E-02 1.95E-OS 4. 62E-Ol 

9.00E+02 1. 43E-OS 3.4SE-02 O.OOE+OO 4.55E-Ol 

1.OOE+03 1. 38E-OS 3. 57E-02 O.OOE+OO 4.49E-Ol 

2.00E+03 9.80E-06 4.lSE-02 O.OOE+OO 3.S9E-Ol 

4.00E+03 4. 96E-06 4.36E-02 O.OOE+OO 2. 93E-Ol 

8.00E+03 1. 27E-06 3. 24E-02 O.OOE+OO 1. 66E-Ol 

1.OOE+04 6.43E-07 2.60E-02 O.OOE+OO 1.25E-Ol 

B-278 
CLASS W .AMAD = 1 KICRON BALFLIFE= 3.21£+03 DAYS EUROPIUM 154 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 6.89E-02 2.76E-Ol 2.3SE-Ol S.72E-02 6.37E-Ol 

2.00E-OI 6.7lE-02 2.6SE-OI 1.97E-OI 1.OSE-OI 6.3SE-Ol 

3.00E-OI 6.S7E-02 2.S6E-Ol 1.66E-OI I.4SE-OI 6. 33E-OI 

4.00E-OI 6.47E-02 2.47E-OI I.39E-Ol 1. 79E-OI 6.30E-Ol 

S.OOE-Ol 6. 39E-02 2.40E-OI 1.l7E-0l 2.06E-Ol 6. 26E-OI 

6.00E-Ol 6. 33E-02 2.33E-Ol 9.86E-02 2.27E-OI 6.2lE-OI 

7.00E;"Ol 6. 29E-02 2. 27E-Ol 8.29E-02 2.43E-OI 6. ISE-OI 

8.00E-Ol 6.2SE-02 2.2lE-OI 6.97E-02 2. 54E-Ol 6.07E-Ol I 9.00E-Ol 6.23E-02 2.l6E-0l 5. 86E-02 2.6IE-Ol 5. 98E-Ol 

1.00E+OO 6.2lE-02 2.llE-Ol 4. 93E-02 2.6SE-Ol S.87E-Ol 

2.00E+OO 6.I7E-02 I.77E-Ol 8.7lE-03 2.03E-0l 4.SIE-Ol 

3.00E+OO 6. 19E-02 I.60E-Ol 1. 54E-03 I.13E-OI 3. 36E-Ol 

4.00E+OO 6.20E-02 1. SOE-OI 2.72E-04 S.7IE-02 2.70E-0l 

S.OOE+OO 6.22E-02 1.44E-Ol 4.8lE-OS 2. 84E-02 2.3SE-Ol 

6.00E+OO 6.24E-02 1.4IE-Ol 8.50E-06 1. 46E-02 2.l8E-0l 

7. o OE+O 0 6. 26E-02 1. 38E-Ol 1.50E-06 8.l2E-03 2.09E-Ol 

8.00E+OO 6. 28E-02 I.36E-OI 2.66E-07 S.02E-03 2.03E-0l 

9.00E+OO 6.30E-02 1.34E-Ol 4. 69E-08 3.S4E-03 2.00E-Ol 

1.OOE+Ol 6. 32E-02 1.32E-OI O.OOE+OO 2.8lE-03 1.98E-OI 

2.00E+Ol 6. 56E-02 1. 16E-Ol O.OOE+OO 1. 86E-03 1.83E-OI 

3.00E+Ol 6.8IE-02 I.02E-Ol O.OOE+OO 1.62E-03 1.71E-Ol 

4.00E+Ol 7.0SE-02 8.93E-02 O.OOE+OO I.4lE-03 I.61E-Ol 

5.00E+OI 7.27E-02 7.84E-02 O.OOE+OO 1.22E-03 I.S2E-Ol 

6.00E+OI 7.47E-02 6. 89E-02 O.OOE+OO 1.06E-03 1.4SE-OI 

7.00E+Ol 7. 65E-02 6.0SE-02 O.OOE+OO 9.2IE-04 1.38E-0l 

8.00E+Ol 7.8lE-02 5.3lE-02 O.OOE+OO 8.00E-04 1. 32E-Ol 

9.00E+Ol 7. 94E-02 4. 66E-02 O.OOE+OO 6.9SE-04 1.27E-Ol 

1.OOE+02 8.07E-02 4.09E-02 O.OOE+OO 6.04E-04 1.22E-OI 

2.00E+02 8.60E-02 1.lOE-02 O.OOE+OO 1.48E-04 9.72E-02 

3.00E+02 8.52E-02 2. 95E-03 O.OOE+OO 3.61E-OS 8. 82E-02 

4.00E+02 8.2SE-02 7.85E-04 O.OOE+OO 8.84E-06 8.33E-02 

S.OOE+02 7. 94E-02 2.07E-04 O.OOE+OO 2.l6E-06 7. 96E-02 

6.00E+02 7. 63E-02 5. 44E-OS O.OOE+OO 5.29E-07 7. 63E-02 

7.00E+02 7.32E-02 1. 42E-05 O.OOE+OO I.30E-07 7. 32E-02 

8.00E+02 7.02E-02 3.70E-06 O.OOE+OO 3.17E-08 7.02E-02 

9.00E+02 6. 74E-02 9. 59E-07 O.OOE+OO O.OOE+OO 6. 74E-02 

1.00E+03 6.47E-02 2.48E-07 O.OOE+OO O.OOE+OO 6. 47E-02 

2.00E+03 4.27E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 27E-02 

4.00E+03 1. 87E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.87E-02 

S.OOE+03 1. 24E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 24E-02 

7.00E+03 S.40E-03 O.OOE+OO O.OOE+OO O.OOE+OO 5.40E-03 

8.00E+03 3. 57E-03 O.OOE+OO O.OOE+OO O.OOE+OO 3.S7E-03 

9.00E+03 2. 36E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.36E-03 

1.00E+04 1. 56E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 56E-03 

2.00E+04 2. 49E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2.49E-05 

B-279 
CLASS W AHAD = 1 MICRON BALFLI:FE= 3.21E+03 DAYS EUROPIUM 154 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.12E-OJ S.lOE-06 

2.00E-Ol 4.0SE-OJ 1. 64E-04 

J.OOE-Ol S.SJE-OJ S.29E-04 

4.00E-Ol 6.6SE-OJ 2. 42E-OJ 

S.OOE-Ol 7. S2E-OJ S.2SE-OJ 

6.00E-Ol S.lSE-OJ 9.61E-OJ 

7.00E-Ol S.70E-OJ 1.SSE-02 

S.OOE-Ol 9.l0E-OJ 2. JOE-02 

9.00E-Ol 9.4lE-OJ 3.19E-02 

1.OOE+OO 9. 66E-OJ 9. 66E-OJ 4.2lE-02 4.21E-02 

2.00E+OO 9.S2E-04 1.06E-02 1.JSE-Ol 1.77E-Ol 

J.OOE+OO 3.S2E-04 l.lOE-02 1.14E-Ol 2.91E-Ol 

4.00E+OO J.27E-04 1.13E-02 6.6JE-02 3. SSE-Ol 

S.OOE+OO 3.08E-04 1.16E-02 3.4lE-02 3. 92E-Ol 

6.00E+OO 2. 94E-04 1.19E-02 1.70E-02 4.09E-Ol 

7.00E+OO 2.8lE-04 1.22E-02 8. 76E-03 4.17E-Ol 

8.00E+OO 2. 69E-04 1.2SE-02 4.82E-OJ 4.22E-Ol 

9.00E+OO 2.S7E-04 1. 27E-02 2. 96E-OJ 4.2SE-Ol 

1.OOE+Ol 2. 47E-04 1. JOE-02 2.06E-03 4.27E-Ol 

2.00E+Ol 1.70E-04 l.SOE-02 1.08E-03 4. 38E-Ol 

3.00E+Ol 1.29E-04 1.64E-02 9.37E-04 4.47E-Ol 

4.00E+Ol 1.OSE-04 l.7SE-02 S.14E-04 4.SSE-Ol 

S.OOE+Ol 8.9SE-OS 1.S4E-02 7.07E-04 4. 62E-Ol 

6.00E+Ol 7. 92E-OS 1.92E-02 6.14E-04 4. 67E-Ol 

7.00E+Ol 7.lSE-OS 1. 99E-02 S.34E-04 4. 72E;E.l 

8.00E+Ol 6.S3E-OS 2.0SE-02 4. 64E-04 4.76E-Ol 

9.00E+Ol 6.01E-OS 2.l1E-02 4.03E-04 4.79E-0l 

1.OOE+02 S.S6E-OS 2.17E-02 3.S0E-04 4.S2E-Ol 

2.00E+02 2.9SE-OS 2.S2E-02 8.S6E-OS 4.90E-Ol 

3.00E+02 2.07E-OS 2.71E-02 2.09E-OS 4.S4E-Ol 

4.00E+02 1.7SE-OS 2. 83E-02 S.12E-06 4.7SE-Ol 

S.OOE+02 1.61E-OS 2. 94E-02 1.2SE-06 4.6SE-Ol 

6.00E+02 1.S2E-OS 3.03E-02 3.07E-07 4.SSE-Ol 

7.00E+02 1.4SE-OS 3.11E-02 7.S0E-OS 4.4SE-Ol 

S.OOE+02 1.39E-OS 3.19E-02 1.84E-08 4. 36E-Ol 

9.00E+02 1. 33E-OS 3.2SE-02 O.OOE+OO 4. 26E-Ol 

1.OOE+03 1.2SE-05 3.31E-02 O.OOE+OO 4.17E-Ol 

2.00E+03 S.47E-06 3.61E-02 O .. OOE+OO 3. 36E-Ol 

4.00E+03 3.70E-06 3.2SE-02 O.OOE+OO 2.18E-Ol 

7.00E+03 1.07E-06 2.14E-02 O.OOE+OO 1.14E-Ol 

9.00E+03 4. 67E-07 1.50E-02 O.OOE+OO 7. 42E-02 

B-2S0 
CLASS II AMAD "" 1 MICRON STABLE GADOLINIUM 157 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.77E-02 2.76E-01 2.35E-01 5.72E-02 6. 36E-01 

2.00E-01 6.48E-02 2. 65E-01 1. 97E-01 1.05E-01 6.33E-01 

3.00E-01 6. 26E-02 2.56E-01 1.66E-01 1.46E-01 6.30E-01 

4.00E-01 6.09E-02 2. 47E-01 1. 39E-01 1. 79E-01 6. 26E-01 

5.00E-0l S.96E-02 2.40E-01 1. 17E-0l 2.06E-01 6. 22E-01 

6.00E-01 5.87E-02 2. 33E-01 9. 86E-02 2. 27E-01 6. 17E-01 

7.00E-01 5.80E-02 2.27E-01 8. 29E-02 2.43E-01 6.10E-0l 

8.00E-01 5. 74E-02 2.21E-01 6. 97E-02 2. 54E-01 6.02E-01 

9.00E-01 5.71E-02 2. 16E-01 5.86E-02 2.61E-01 5. 93E-01 

1.00E+OO 5. 68E-02 2. 11E-01 4. 93E-02 2. 65E-01 5.82E-01 

2.00E+OO 5.61E-02 1. 77E-Ol 8. 72E-03 2.03E-01 4. 46E-Ol 

3.00E+OO 5.63E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3.3lE-Ol 

4.00E+OO 5.65E-02 1.50E-Ol 2. 72E-04 5.72E-02 2. 64E-01 

5.00E+OO S.68E-02 1.45E-Ol 4. 82E-05 2. 85E-02 2.30E-Ol 

6.00E+OO 5.71E-02 1. 41E-Ol 8.5lE-06 1.47E-02 2. 13E-01 

7.00E+OO 5. 73E-02 1. 38E-Ol 1.51E-06 8. 14E-03 2.04E-01 

8.00E+OO 5.76E-02 1. 36E-01 2.66E-07 S.04E-03 1.99E-Ol 

9.00E+OO S.79E-02 1. 34E-01 4.70E-08 3.S5E-03 1.9SE-01 

1.00E+01 S.82E-02 1.32E-01 O.OOE+OO 2. 82E-03 1. 93E-01 

2.00E+Ol 6.09E-02 1. 16E-01 O.OOE+OO 1. 87E-03 1.79E-01 

3.00E+Ol 6. 36E-02 1.02E-Ol O.OOE+OO 1.63E-03 1.68E-0l 

4.00E+Ol 6.61E-02 9.01E-02 O.OOE+OO 1.42E-03 1.S8E-Ol 

S.OOE+Ol 6.84E-02 7. 93E-02 O.OOE+OO 1.23E-03 1.49E-0l 

6.00E+01 7.0SE-02 6. 98E-02 O.OOE+OO 1.07E-03 1.41E-Ol 

7.00E+01 7.24E-02 6. 14E-02 O.OOE+OO 9. 36E-04 1.35E-Ol 

8.00E+01 7.41E-02 5.40E-02 O.OOE+OO 8.1SE-04 1.29E-Ol 

9.00E+01 7.S6E-02 4. 75E-02 O.OOE+OO 7.09E-04 1. 24E-01 

1.00E+02 7.69E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1. 19E-Ol 

2.00E+02 8. 39E-02 1.lSE-02 O.OOE+OO 1. S4E-04 9.S6E-02 

3.00E+02 8.49E-02 3.1SE-03 O.OOE+OO 3.86E-05 8.81E-02 

4.00E+02 8.4lE-02 8.5SE-04 O.OOE+OO 9.6SE-06 8.50E-02 

S.OOE+02 8.27E-02 2.3lE-04 O.OOE+OO 2.4lE-06 8.29E-02 

6.00E+02 8.l1E-02 6. I9E-OS O.OOE+OO 6.03E-07 8.l2E-02 

7.00E+02 7. 96E-02 1. 65E-OS O.OOE+OO 1.5IE-07 7. 96E-02 

8.00E+02 7.80E-02 4.40E-06 O.OOE+OO 3.77E-OB 7. BOE-02 

9.00E+02 7.65E-02 l.l6E-06 O.OOE+OO O.OOE+OO 7.6SE-02 

1.OOE+03 7. SOE-02 3.08E-07 O.OOE+OO O.OOE+OO 7.S0E-02 

2.00E+03 6.lSE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.l5E-02 

4.00E+03 4.l4E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l4E-02 

5.00E+03 3.40E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.40E-02 

7.00E+03 2.29E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 29E-02 

8.00E+03 1.88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 88E-02 

1.OOE+04 1.26E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.26E-02 

2.00E+04 1. 74E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 74E-03 

B-281 
CLASS W AMAD = 1 MICRON STABLE GADOLINIUM 157 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-0l 3.30E-03 8.10E-06 

2.00E-Ol 6.3lE-03 1. 64E-04 

3.00E-OI 8. 59E-03 8. 29E-04 

4.00E-OI I.03E-02 2.42E-03 

5.00E-OI I.17E-02 5. 28E-03 

6.00E-Ol I.27E-02 9.61E-03 

7.00E-OI I.34E-02 I.55E-02 

8.00E-OI 1.40E-02 2.30E-02 

9.00E-Ol I.45E-02 3.l9E-02 

1.00E+OO 1. 48E-02 1.48E-02 4.21E-02 4.21E-02 

2.00E+OO 1. 22E-03 1.6IE-02 1.35E-Ol I.77E-OI 

3.00E+OO 3. 13E-04 1. 64E-02 1. 14E-Ol 2. 92E-OI 

4.00E+OO 2. 46E-04 1. 66E-02 6. 65E-02 3. 58E-Ol 

5.00E+OO 2. 34E-04 1. 69E-02 3. 42E-02 3. 92E-Ol 

6.00E+OO 2. 26E-04 I.7IE-02 I.71E-02 4.09E-OI 

7.00E+OO 2.l9E-04 1. 73E-02 8. 78E-03 4.l8E-OI 

8.00E+OO 2.12E-04 I.75E-02 4.84E-03 4.23E-0l 

9.00E+OO 2.06E-04 I.77E-02 2. 97E-03 4. 26E-Ol 

I.OOE+OI 2.00E-04 1.79E-02 2.07E-03 4. 28E-OI 

2.00E+OI 1. 56E-04 I.97E-02 I.09E-03 4.40E-Ol 

3.00E+OI 1. 29E-04 2.l1E-02 9.44E-04 4.5lE-OI 

4.00E+OI I.I2E-04 2. 22E-02 8. 22E-04 4.S9E-OI 

5.00E+0l 9. 97E-OS 2. 33E-02 7.15E-04 4.67E-OI 

6.00E+Ol 9.0IE-OS 2.42E-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol 8. 22E-OS 2.5IE-02 5. 42E-04 4.79E-0l 

8.00E+OI 7.S4E-OS 2.S9E-02 4.72E-04 4. 84E-Ol 

9.00E+OI 6.9SE-OS 2. 66E-02 4.l1E-04 4.89E-Ol 

I.OOE+02 6.4IE-05 2. 73E-02 3.S8E-04 4. 93E-OI 

2.00E+02 3. 27E-OS 3.18E-02 8. 94E-05 5.12E-Ol 

3.00E+02 2.18E-OS 3. 44E-02 2. 24E-05 5.l7E-Ol 

4.00E+02 1.8lE-05 3. 64E-02 S.59E-06 5.18E-0l 

5.00E+02 1. 68E-05 3. 82E-02 I.40E-06 S.18E-OI 

6.00E+02 1. 62E-05 3.98E-02 3.49E-07 5.l8E-Ol 

7.00E+02 1. 58E-05 4.14E-02 8. 73E-08 S.18E-Ol 

8.00E+02 1. 55E-OS 4.30E-02 2.l8E-08 5.18E-Ol 

9.00E+02 1.S2E-05 4. 45E-02 O.OOE+OO 5.18E-Ol 

I.OOE+03 I.49E-05 4.60E-02 O.OOE+OO S.I8E-OI 

2.00E+03 1.22E-05 S.9SE-02 O.OOE+OO S.18E-Ol 

4.00E+03 8.20E-06 7. 96E-02 O.OOE+OO 5.l8E-Ol 

8.00E+03 3.71E-06 I.02E-Ol O.OOE+OO 5.18E-Ol 

1.00E+04 2.50E-06 1.08E-Ol O.OOE+OO 5.18E-Ol 

B-282 
CLASS W AMAD = 1 MICRON STABLE TERBIUM. 159 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-0l 6.80E-02 2.76E-0l 2. 35E-01 5.72E-02 6.36E-OI 

2.00E-OI 6. 54E-02 2. 65E-OI I.97E-OI I.05E-OI 6. 33E-Ol 

3.00E-OI 6. 33E-02 2. 56E-OI 1. 66E-OI I.46E-OI 6.30E-OI 

4.00E-OI 6.l8E-02 2. 47E-Ol 1.39E-OI 1. 79E-OI 6.27E-Ol 

5.00E-OI 6.07E-02 2.40E-Ol I.17E-OI 2.06E-Ol 6.23E-OI 

6.00E-OI 5.98E-02 2.33E-Ol 9. 86E-02 2.27E-Ol 6.l8E-OI 

7.00E-OI 5.9lE-02 2.27E-Ol 8.29E-02 2.43E-OI 6.llE-OI 

8.00E-OI 5. 86E-02 2.2IE-Ol 6. 97E-02 2. 54E-Ol 6.03E-Ol 

9.00E-Ol 5. 83E-02 2.16E-Ol 5.86E-02 2.6lE-0l 5. 94E-Ol 

I.OOE+OO 5.80E-02 2.11E-Ol 4. 93E-02 2. 65E-Ol 5. 83E-Ol 

2.00E+OO 5. 73E-02 I.77E-Ol 8. 72E-03 2.03E-Ol 4.47E-OI 

3.00E+OO 5. 75E-02 1.60E-Ol 1.54E-03 I.l3E-OI 3. 32E-Ol 

4.00E+OO 5. 76E-02 I.50E-Ol 2.72E-04 5.72E-02 2. 65E-OI 

5.00E+OO 5. 78E-02 I.45E-Ol 4. 82E-05 2. 85E-02 2.3lE-Ol 

6.00E+OO 5. 81E-02 1.41E-0l 8.5lE-06 I.47E-02 2.14E-OI 

7.00E+OO 5.83E-02 1. 38E-OI 1.5IE-06 8.14E-03 2.05E-Ol 

8.00E+OO 5. 85E-02 I.36E-OI 2. 66E-07 5.04E-03 I.99E-OI 

9.00E+OO 5.87E-02 1.34E-OI 4. lOE-08 3. 55E-03 I.96E-OI 

I.OOE+Ol 5.89E-02 1. 32E-OI O.OOE+OO 2. 82E-03 I.94E-Ol 

2.00E+OI 6.14E-02 1.I6E-Ol O.OOE+OO 1. 87E-03 1. 79E-OI 

3.00E+OI 6.39E-02 1.02E-OI O.OOE+OO I.63E-03 1.68E-Ol 

4.00E+OI 6. 63E-02 9.0lE-02 O.OOE+OO 1. 42E-03 I.58E-Ol 

5.00E+Ol 6.86E-02 7.93E-02 O.OOE+OO 1.23E-03 1.49E-OI 

6.00E+Ol 7.06E-02 6. 98E-02 O.OOE+OO I.07E-03 I.4lE-OI 

7.00E+Ol 7.25E-02 6.14E-02 O.OOE+OO 9. 36E-04 I.35E-Ol 

8.00E+OI 7.42E-02 5.40E-02 O.OOE+OO 8.l5E-04 1. 29E-Ol 

9.00E+Ol 7.57E-02 4. 75E-02 O.OOE+OO 7.09E-04 1. 24E-0l 

1.OOE+02 7.70E-02 4.l8E-02 O.OOE+OO 6.17E-04 I.I9E-OI 

2.00E+02 8.39E-02 1. ISE-02 O.OOE+OO 1.54E-04 9. 56E-02 

3.00E+02 8.50E-02 3.15E-03 O.OOE+OO 3. 86E-OS 8.8IE-02 

4.00E+02 8.4IE-02 8. 55E-04 O.OOE+OO 9.65E-06 8.50E-02 

5.00E+02 8.27E-02 2.3IE-04 O.OOE+OO 2.4IE-06 8. 29E-02 

6.00E+02 8.11E-02 6.l9E-05 O.OOE+OO 6.03E-07 B.12E-02 

7.00E+02 7.96E-02 I.65E-05 O.OOE+OO 1.5IE-07 7. 96E-02 

B.OOE+02 7. BOE-02 4.40E-06 O.OOE+OO 3.77E-OB 7. BOE-02 

9.00E+02 7.65E-02 I.16E-06 O.OOE+OO O.OOE+OO 7. 65E-02 

1.OOE+03 7.50E-02 3.0BE-07 O.OOE+OO O.OOE+OO 7.50E-02 

2.00E+03 6.15E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.15E-02 

4.00E+03 4.l4E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l4E-02 

5.00E+03 3.40E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.40E-02 

7.00E+03 2. 29E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 29E-02 

8.00E+03 I.BBE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 88E-02 

I.OOE+04 1. 26E-02 O.OOE+OO O.OOE+OO O.OOE+OO I.26E-02 

2.00E+04 1. 74E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 74E-03 . 

B-2B3 
CLASS V AHAD ::0 1 MICRON STABLK '!'ERBIUM 159 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.0lE-03 B.lOE-06 

2.00E-Ol S.7SE-03 1. 64E-04 

3.00E-Ol 7.B4E-03 B.29E-04 

4.00E-Ol 9.43E-03 2. 42E-03 

S.OOE-Ol 1.06E-02 S. ZBE-03 

6.00E-Ol 1. 16E-02 9.6lE-03 

7.00E-Ol 1. 23E-02 1. SSE-02 

B.OOE-Ol 1.2BE-02 2.30E-02 

9.00E-Ol 1.33E-02 3. 19E-02 

1.OOE+OO 1. 36E-02 1.36E-02 4. 21E-02 4.21E-02 

2.00E+OO 1.2lE-03 1.4BE-02 1.3SE-0l 1.77E-Ol 

3.00E+OO 3.BIE-04 1. S2E-02 1.14E-OI 2. 92E-Ol 

4.00E+OO 3.lSE-04 1. SSE-02 6.6SE-02 3. SBE-Ol 

S.OOE+OO 2. 99E-04 I.SBE-02 3. 42E-02 3. 92E-Ol 

6.00E+OO 2.B7E-04 1. 61E-02 1.71E-02 4.09E-Ol 

7.00E+OO 2.7SE-04 1. 64E-02 B.7BE-03 4.lBE-OI 

B.OOE+OO 2.6SE-04 1.66E-02 4. B4E-03 4.23E-Ol 

9.00E+OO 2.SSE-04 1.69E-02 2. 97E-03 4. 26E-Ol 

1.OOE+Ol 2.46E-04 1.7lE-02 2.07E-03 4.2BE-Ol 

2.00E+Ol 1. BOE-04 1. 92E-02 1.09E-03 4.40E-Ol 

3.00E+Ol 1.42E-04 2.0BE-02 9.44E-04 4.SlE-Ol 

4.00E+Ol l.l9E-04 2.2lE-02 B.22E-04 4.S9E-Ol 

S.OOE+Ol 1.04E-04 2. 32E-02 7.1SE-04 4.67E-Ol 

6.00E+Ol 9.2SE-OS 2.4lE-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol B.3BE-OS 2.S0E-02 S.42E-04 4. 79E-Ol 

B.OOE+Ol 7. 66E-oS 2.SBE-02 4. 72E-04 4~B4E-Ol 

9.00E+Ol 7.04E-OS 2.6SE-02 4.11E-04 4.B9E-Ol 

1.OOE+02 6. 49E-OS 2. 72E-02 3.SBE-04 4. 93E-Ol· 

2.00E+02 3.29E-OS 3.1BE-02 B.94E-OS S.12E-OI 

3.00E+02 2.l9E-OS 3. 44E-02 2. 24E-OS S.17E-Ol 

4.00E+02 I.B2E-OS 3. 64E-02 S.S9E-06 S.IBE-Ol 

S.OOE+02 1.6BE-OS 3.BlE-02 1.40E-06 S.lBE-Ol 

6.00E+02 1.62E-OS 3.9BE-02 3.49E-07 S.lBE-Ol 

7.00E+02 1.SBE-OS 4.l4E-02 B.73E-OB S.lBE-Ol .. .. B.OOE+02 1. SSE-OS 4.30E-02 2.lBE-OB S.lBE-Ol 

9.00E+02 1.S2E-OS 4.4SE-02 O.OOE+OO S.lBE-Ol 

1.00E+03 1.49E-OS 4.60E-02 O.OOE+OO S.lBE-OI 

2.00E+03 1.22E-OS S.9SE-02 O.OOE+OO S.lBE-Ol 

4.00E+03 B.20E-06 7.96E-02 O.OOE+OO S.lBE-Ol 

B.OOE+03 3.7lE-06 1.02E-Ol O.OOE+OO S.lBE-Ol 

l.OOE+04 2. SOE-06 1.08E-0l O.OOE+OO S.lBE-Ol 

B-284 
CLASS V AMAD= 1 KICRON STABLE DYSPROSIUM 162 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 68E-02 2. 76E-OI 2. 35E-OI 5.72E-02 6. 35E-Ol 

2.00E-OI 6.3IE-02 2. 65E-OI 1. 97E-Ol I.05E-Ol 6.3lE-Ol 

3.00E-OI 6.03E-02 2.56E-Ol 1.66E-0i 1.46E-Ol 6.27E-Ol 

4.00E-OI 5.8lE-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6. 24E-Ol 

5.00E-Ol 5. 65E-02 2.40E-Ol 1.17E-0i 2.06E-Ol 6.19E-0l 

6.00E-Ol 5. 53E-02 2.33E-Ol 9. 86E-02 2. 27E-Ol 6.l3E-Ol 

7.00E-Ol 5. 44E-02 2. 27E-0l 8.29E-02 2.43E-Ol 6.07E-Ol 

8.00E-OI 5. 37E-02 2.2IE-Ol 6. 97E-02 2. 54E-Ol 5. 98E-Ol 

9.00E-Ol 5. 32E-02 2.l6E-Ol 5.86E-02 2.6lE-0i 5. 89E-OI 

1.OOE+OO 5.28E-02 2.llE-Ol 4. 93E-02 2. 65E-Ol 5. 78E-Ol 

2.00E+OO 5.19E-02 1.77E-OI 8.72E-03 2.03E-Ol 4.41E-Ol 

3.00E+OO 5.2IE-02 1.60E-Ol 1. 54E-03 1.13E-OI 3. 27E-Ol 

4.00E+OO 5. 23E-02 I.50E-Ol 2. 72E-04 S.72E-02 2.60E-OI 

5.00E+OO 5. 26E-02 1.45E-Ol 4. 82E-OS 2. 85E-02 2.26E-Ol 

6.00E+OO 5.29E-02 1.4lE-0i 8.51E-06 1. 47E-02 2.08E-Ol 

7.00E+OO 5. 32E-02 1.38E-Ol I.5IE-06 8.l4E-03 1. 99E-OI 

8.00E+OO 5.34E-02 I.36E-Ol 2. 66E-07 S.04E-03 1.94E-OI 

9.00E+OO 5. 37E-02 1.34E-OI 4.70E-08 3. 55E-03 I.9IE-OI 

I.OOE+OI S.40E-02 1.32E-0i O.OOE+OO 2.82E-03 I.89E-OI 

2.00E+Ol 5. 67E-02 I.16E-OI O.OOE+OO 1. 87E-03 1. 75E-OI 

3.00F+OI 5. 93E-02 I.02E-OI O.OOE+OO 1. 63E-03 1.63E-Ol 

4.00E+Gl 6.17E-02 9.0IE-02 O.OOE+OO 1. 42E-03 1. 53E-OI 

S.OOE+OI 6. 38E-02 7. 93E-02 O.OOE+OO I.23E-03 I.44E-OI 

6.00E+Ol 6. 58E-02 6.98E-02 O.OOE+OO I.07E-03 I.37E-Ol 

7.00E+OI 6. 76E-02 6.l4E-02 O.OOE+OO 9. 36E-04 I.30E-OI 

8.00E+Ol 6.9IE-02 5.40E-02 O.OOE+OO 8.l5E-04 I.24E-OI 

9.00E+OI 7.05E-02 4.7SE-02 O.OOE+OO 7.09E-04 I.l9E-OI 

I.OOE+02 7.l8E-02 4.18E-02 O.OOE+OO 6.17E-04 I.I4E-OI 

2.00E+02 7.83E-02 I.I5E-02 O.OOE+OO I.54E-04 9.00E-02 

3.00E+02 7. 93E-02 3.15E-03 O.OOE+OO 3. 86E-OS 8.2SE-02 

4.00E+02 7.85E-02 8. 55E-04 O.OOE+OQ 9. 65E-06 7. 94E-02 

5.00E+02 7.72E-02 2.3IE-04 O.OOE+OO 2.4IE-06 7. 74E-02 

6.00E+02 7.S7E-02 6.19E-05 O.OOE+OO 6.03E-07 7.58E-02 

7.00E+02 7. 43E-02 1. 65E-05 O.OOE+OO I.SlE-07 7. 43E-02 

8.00E+02 7.28E-02 4.40E-06 O.OOE+OO 3. 77E-08 7. 28E-02 

. '-, . , 9.00E+02 7.14E-02 1.I6E-06 O.OOE+OO O.OOE+OO 7.l4E-02 

I.OOE+03 7.00E-02 3.08E-07 O.OOE+OO O.OOE+OO 7.00E-02 

2.00E+03 5. 74E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.74E-02 

4.00E+03 3.86E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.86E-02 

5.00E+03 3.17E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.17E-02 

7.00E+03 2.13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.13E-02 

8.00E+03 1. 75E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.7SE-02 

I.OOE+04 1.I8E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.18E-02 

2.00E+04 1. 63E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 63E-03 

13-285 
CLASS W AHA» == 1 KICRON STABLE DYSPROSIUM 162 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.l9E-03 8.lOE-06 

2.00E-Ol 8.0lE-03 1. 64E-04 

3.00E-Ol 1.09E-02 8. 29E-04 

4.00E-Ol 1.3lE-02 2.42E-03 

5.00E-Ol 1. 48E-02 5.28E-03 

6.00E-Ol 1.6lE-02 9.6lE-03 

7.00E-Ol 1.70E-02 1. 55E-02 

B.OOE-Ol 1.7BE-02 2.30E-02 

9.00E-Ol 1. 84E.;.02 3.19E-02 

1.OOE+OO 1. 88E-02 1.BBE-02 4.2lE-02 4.2lE-02 

2.00E+OO 1.47E-03 2.03E-02 1.35E-Ol 1.77E-Ol 

3.00E+OO 3.17E-04 2.06E-02 1.14E-Ol 2. 92E-Ol 

4.00E+OO 2. 37E-04 2.0BE-02 6.65E-02 3.5BE-Ol 

5.00E+OO 2. 26E-04 2.10E-02 3.42E-02 3. 92E-Ol 

6.00E+OO 2.20E-04 2.13E-02 1.71E-02 4.09E-Ol 

7.00E+OO 2.14E-04 2.15E-02 8. 78E-03 4.18E-Ol 

8.00E+OO 2.09E-04 2.l7E-02 4.84E-03 4.23E-Ol 

9.00E+OO 2.04E-04 2.19E-02 2. 97E-03 4. 26E-Ol 

1.OOE+Ol 2.00E-04 2.21E-02 2.07E-03 4.28E-Ol 

2.00E+Ol 1. 65E-04 2. 39E-02 1.09E-03 4.40E-Ol 

3.00E+Ol 1. 42E-04 2. 54E-02 9. 44E-04 4.5lE-Ol 

4.00E+Ol 1. 26E-04 2. 67E-02 8.22E-04 4. 59E-Ol 

S.OOE+Ol 1.13E-04 2. 79E-02 7.15E-04 4. 67E-Ol 

6.00E+Ol 1.03E-04 2.90E-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol 9.36E-05 3.00E-02 5.42E-04 4. 79E-Ol 

8.00E+Ol 8. 57E-05 3.08E-02 4.72E-04 4. 84E-Ol 

9.00E+Ol 7.87E-05 3.17E-02 4.11E-04 4.89E-Ol 

1.OOE+02 7. 23E-05 3. 24E-02 3.5BE-04 4. 93E-Ol 

2.00E+02 3. 46E-05 3. 74E-02 B.94E-05 5.12E-Ol 

3.00E+02 2.l6E-05 4.01E-02 2. 24E-05 5.17E-Ol 

4.00E+02 1.73E-OS 4.20E-02 5.S9E-06 S.18E-Ol 

S.OOE+02 1.S8E-OS 4. 37E-02 1.40E-06 5.l8E-Ol 

6.00E+02 1.5lE-05 4.52E-02 3. 49E-07 5.18E-Ol 

7.00E+02 1. 47E-05 4. 67E-02 B.73E-OB S.18E-Ol 

8.00E+02 1. 44E-05 4. 82E-02 2.l8E-08 5.l8E-Ol 

9.00E+02 1.4lE-05 4. 96E-02 O.OOE+OO S.18E-Ol 

1.OOE+03 1. 39E-OS S.lOE-02 O.OOE+OO 5.l8E-Ol 

2.00E+03 1.14E-05 6. 36E-02 O.OOE+OO 5.lBE-Ol 

4.00E+03 7.65E-06 B.23E-02 O.OOE+OO S.lBE-Ol 

B.OOE+03 3. 47E-06 1.03E-Ol O.OOE+OO 5.lBE-Ol 

1.OOE+04 2. 33E-06 1.09E-Ol O.OOE+OO 5.l8E-Ol 

B-286 
CLASS W AM.AD ... 1 MICRON STABLE HOLMIUM 165 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 87E-02 2. 76E-01 2.35E-01 5.72E-02 6.37E-01 

2.00E-01 6. 68E-02 2. 65E-01 1. 97E-01 1.05E-01 6. 35E-01 

3.00E-01 6. 53E...;02 2.56E-01 1.66E-01 1.46E-01 6.32E-01 

4.00E-01 6. 42E-02 2. 47E-01 1. 39E-01 1.79E-01 6.30E-01 

5.00E-01 6.34E-02 2.40E-01 1. 17E-01 2.06E-01 6.26E-01 

6.00E-01 6. 28E-02 2. 33E-01 9. 86E-02 2.27E-01 6.21E-01 

7.00E-01 6.23E-02 2.27E-01 8.29E-02 2.43E-01 6. 15E-01 

8.00E-01 6.20E-02 2.21E-01 6. 97E-02 2. 54E-01 6.07E-01 

9.00E-01 6. 17E-02 2.16E-01 5. 86E-02 2.61E-Ol 5. 97E-01 

1.00E+OO 6. 16E-02 2.11E-Ol 4. 93E-02 2. 65E-01 S.87E-01 

2.00E+OO 6. 14E-02 1. 77E-Ol 8.72E-03 2.03E-Ol 4.S1E-Ol 

3.00E+OO 6.17E-02 1.60E-Ol 1. 54E-03 1.l3E-Ol 3. 36E-01 

4.00E+OO 6. 22E-02 1.50E-Ol 2. 72E-04 5.72E-02 2.70E-Ol 

S.OOE+OO 6. 26E-02 1. 45E-01 4. 82E-05 2. 85E-02 2. 36E-01 

6. ()()K'+OO 6.30E-02 1.41E-0l 8.SlE-06 1.47E-02 2. 18E-Ol 

7.00E+OO 6. 34E-02 1. 38E-Ol 1.SlE-06 8.14E-03 2.10E-Ol 

8.00E+OO 6.38E-02 1.36E-Ol 2. 66E-07 5.04E-03 2.0SE-0l 

9.00E+OO 6.42E-02 1. 34E-Ol 4.70E-08 3. 55E-03 2.02E-Ol 

1.OOE+Ol 6. 46E-02 1.32E-01 O.OOE+OO 2. 82E-03 1.99E-Ol 

2.00E+01 6. 83E-02 1. 16E-01 O.OOE+OO 1.87E-03 . 1. 86E-01 

3.00E+01 7.16E-02 1.02E-01 O.OOE+OO 1.63E-03 1.76E-Ol 

4.00E+Ol 7. 46E-02 9.01E-02 O.OOE+OO 1. 42E-03 1.66E-Ol 

S.OOE+01 7. 73E-02 7. 93E-02 O.OOE+OO 1.23E-03 1.58E-Ol 

6.00E+Ol 7. 97E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.SlE-Ol 

7.00E+01 8.19E-02 6.14E-02 O.OOE+OO 9.36E-04 1. 44E-Ol 

8.00E+01 8. 38E-02 S.40E-02 O.OOE+OO 8.15E-04 1. 39E-Ol 

9.00E+Ol 8. SSE-02 4. 75E-02 O.OOE+OO 7.09E-04 1.34E-Ol 

1.OOE+02 8.71E-02 4. 18E-02 O.OOE+OO 6.l7E-04 1.29E-01 

2.00E+02 9. SOE-02 1.lSE-02 O.OOE+OO 1. S4E-04 1.07E-Ol 

3.00E+02 9. 63E-02 3.1SE-03 O.OOE+OO 3. 86E-05 9. 94E-02 

4.00E+02 9.53E-02 8.55E-04 O.OOE+OO 9.65E-06 9.62E-02 

S.OOE+02 9.37E-02 2.31E-04 O.OOE+OO 2.41E-06 9.40E-02 

6.00E+02 9.20E-02 6. 19E-OS O.OOE+OO 6.03E-07 9.20E-02 

7.00E+02 9.02E-02 1.6SE-05 O.OOE+OO 1.SlE-07 9.02E-02 

8.00E+02 8. 84E-02 4.40E-06 O.OOE+OO 3. 77E-08 8. 84E-02 

9.00E+02 8. 67E-02 1.16E-06 O.OOE+OO O.OOE+OO 8. 67E-02 

1.00E+03 8.50E-02 3.08E-07 O.OOE+OO O.OOE+OO 8.50E-02 

2.00E+03 6. 97E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 97E-02 

4.00E+03 4. 69E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 69E-02 

5.00E+03 3.8SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.8SE-02 

7.00E+03 2. 59E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S9E-02 

8.00E+03 2.13E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.l3E-02 

1.OOE+04 1.43E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.43E-02 

2.00E+04 1. 98E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 98E-03 

B-287 
CLASS W AMAD = 1 MICRON STABLE HOMUJH 165 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 24E-03 8.l0E-06 

2.00E-Ol 4. 28E-03 1. 64E-04 

3.00E-01 S.83E-03 8. 29E-04 

4.00E-Ol 7.00E-03 2. 42E-03 

S.OOE-Ol 7.90E-03 S.28E-03 

6.00E-Ol 8.S8E-03 9.61E-03 

7.00E-Ol 9.lOE-03 1.SSE-02 

8.00E-Ol 9.49E-03 2.30E-02 

9.00E-Ol 9. 79E-03 3.l9E-02 

1.OOE+OO 1.00E-02 1.00E-02 4.2lE-02 4. 21E-02 

2.00E+OO 7. 46E-04 1.0BE-02 1.3SE-Ol 1.77E-Ol 

3.00E+OO 1.31E-04 1.09E-02 1. 14E-Ol 2. 92E-01 

4.00E+OO 9. llE-OS 1.lOE-02 6.6SE-02 3.S8E-Ol 

S.OOE+OO B.77E-OS 1.llE-02 3. 42E-02 3. 92E-Ol 

6.00E+OO 8.67E-OS 1. 12E-02 1.71E-02 4.09E-Ol 

7.00E+OO 8.60E-OS 1.13E-02 B.78E-03 4.l8E-Ol 

8.00E+OO 8.54E-05 1.l3E-02 4.B4E-03 4.23E-Ol 

9.00E+OO 8. 48E-05 1.14E-02 2. 97E-03 4.26E-OI 

I.OOE+OI 8.42E-05 1.15E-02 2.07E-03 4. 28E-Ol 

2.00E+Ol 7.84E-05 1. 23E-02 1.09E-03 4.40E-Ol 

3.00E+Ol 7.3IE-05 1.3lE-02 9.44E-04 4.51E-Ol 

4.00E+Ol 6.8lE-05 1. 38E-02 8.22E-04 4.59E-Ol 

5.00E+Ol 6. 36E-05 1. 44E-02 7.l5E-04 4.67E-Ol 

6.00E+Ol 5. 94E-OS 1.SOE-02 6.23E-04 4. 74E-.Ol 

7.00E+OI S.5SE-OS I.S6E-02 S.42E-04 4. 79E-OI 

8.00E+OI S.20E-OS 1. 62E-02 4. 72E-04 4.B4E-OI 

9.00E+OI 4.B8E-OS 1. 67E-02 4.1IE-04 4. 89E-OI 

1.OOE+02 4.S9E-OS 1.71E-02 3.S8E-04 4. 93E-OI 

2.00E+02 2.83E-05 2.07E-02 8. 94E-OS S.12E-OI 

3.00E+02 2.20E-05 2.3lE-02 2.24E-OS S.17E-OI 

4.00E+02 1.97E-OS 2. S2E-02 S.S9E-06 S.18E-0l 

S.OOE+02 1. 88E-OS 2.7IE-02 1.40E-06 S.18E-OI 

6.00E+02 1.83E-OS 2.90E-02 3. 49E-07 S.18E-Ol 

7.00E+02 1.79E-OS 3.0BE-02 8. 73E-OB S.18E-OI 

" 

8.00E+02 1.7SE-05 3.26E-02 2.18E-08 S.18E-OI 

9.00E+02 1.72E-05 3. 43E-02 O.OOE+OO S.18E-OI 

I.OOE+03 1.68E-OS 3.60E-02 O.OOE+OO S.18E-OI 

2.00E+03 1.38E-05 S.13E-02 O.OOE+OO S.18E-OI 

4.00E+03 9. 29E-06 7.4IE-02 O.OOE+OO S.IBE-OI 

8.00E+03 4.2IE-06 9. 97E-02 O.OOE+OO S.18E-OI 

1.OOE+04 2. 83E-06 1.07E-OI O.OOE+OO S.18E-OI 

B-288 
CLASS W AHAD - 1 MICRON STABLE ERBIUM 167 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.72E-02 2. 76E-OI 2.3SE-01 S.12E-02 6.3SE-01 

2.00E-OI 6.40E-02 2.6SE-OI 1. 97E-Ol 1.OSE-Ol 6. 32E-Ol 

3.00E-Ol 6.1SE-02 2.S6E-Ol 1.66E-Ol 1. 46E-0l 6. 29E-01 

4.00E-Ol S.96E-02 2.47E-Ol 1.39E-Ol 1. 79E-Ol 6.2SE-Ol 

S.OOE-Ol S.8lE-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6.2lE-Ol 

6.00E-Ol S.71E-02 2. 33E-Ol 9. 86E-02 2. 27E-OI 6.1SE-01 

7.00E-Ol S.63E-02 2. 27E-01 8. 29E-02 2. 43E-01 6.08E-01 

8.00E-Ol S.S7E-02 2.21E-Ol 6. 97E-02 2.S4E-Ol 6.00E-01 

9.00E-Ol S. S2E-02 2.l6E-0l S.86E-02 2.6lE-Ol S.91E-Ol 

1.00E+OO S.49E-02 2.llE-OI 4. 93E-02 2.6SE-Ol S.80E-Ol 

2.00E+OO S.42E-02 1. 77E-Ol 8.12E-03 2.03E-OI 4. 44E-OI 

3.00E+OO S.4SE-02 I.60E-OI 1.S4E-03 1. 13E-Ol 3. 29E-Ol 

4.00E+OO S.49E-02 1.S0E-01 2.72E-04 S.12E-02 2. 63E-OI 

5.00E+OO S.52E-02 1.4SE-OI 4. 82E-OS 2.8SE-02 2. 28E-Ol 

6.00E+OO S.56E-02 I.41E-0l 8. SlE-06 1.47E-02 2.l1E-0l 

7.00E+OO S.S9E-02 1. 38E-OI I.S1E-06 8.l4E-03 2.02E-Ol 

8.00E+OO S.63E-02 I.36E-OI 2. 66E-07 S.04E-03 1. 97E-01 

9.00E+OO 5. 66E-02 1. 34E-01 4.70E-08 3.S5E-03 1. 94E-OI 

1.00E+0l S.70E-02 1.32E-01 O.OOE+OO 2.82E-03 1.92E-Ol 

2.00E+0l 6.02E-02 1. 16E-01 O.OOE+OO 1. 87E-03 1. 78E-01 

3.00E+Ol 6. 32E-02 1.02E-Ol O.OOE+OO 1.63E-03 1.67E-Ol 

4.00E+Ol 6. 58E-02 9.01E-02 O.OOE+OO I.42E-03 1.57E-01 

5.00E+OI 6.82E-02 7. 93E-02 O.OOE+OO I.23E-03 1.49E-01 

6.00E+Ol 7.04E-02 6. 98E-02 O.OOE+OO I.07E-03 I.41E-01 

1.00E+01 7.23E-02 6. 14E-02 O.OOE+OO 9.36E-04 1. 35E-01 

9.00E+Ol 7.40E-02 5.40E-02 O.OOE+OO 8.1SE-04 1.29E-Ol 

9.00E+OI 7. 55E-02 4.7SE-02 O.OOE+OO 7.09E-04 1. 24E-01 

1.OOE+02 7. 68E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1. 19E-01 

2.00E+02 8. 39E-02 1.lSE-02 O.OOE+OO 1.54E-04 9. 55E-02 

3.00E+02 8.49E-02 3. ISE-03 O.OOE+OO 3. 86E-OS 8. 81E-02 

4.00E+02 8.41E-02 8. 55E-04 O.OOE+OO 9.6SE-06 8.50E-02 

S.OOE+02 8.27E-02 2. 31E-04 O.OOE+OO 2.4IE-06 8. 29E-02 

6.00E+02 8.l1E-02 6. 19E-OS O.OOE+OO 6.03E-07 8. 12E-02 

7.00E+02 7. 96E-02 1. 65E-OS O.OOE+OO I.SlE-07 7. 96E-02 

8.00E+02 7.80E-02 4.40E-06 O.OOE+OO 3.17E-08 7.80E-02 

9.00E+02 7.65E-02 1. 16E-06 O.OOE+OO O.OOE+OO 7.6SE-02 

1.00E+03 7.50E-02 3.08E-07 O.OOE+OO O.OOE+OO 7.S0E-02 

2.00E+03 6.l5E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.I5E-02 

4.00E+03 4.l4E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 14E-02 

5.00E+03 3.40E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.40E-02 

7.00E+03 2.29E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.29E-02 

8.00E+03 1. 88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 88E-02 

1.00E+04 1.26E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 26E-02 

2.00E+04 I. 74E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 74E-03 

B-289 
CLASS W AMAD = 1 MICRON STABLE ERBIUM 167 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3. 74E-03 B.IOE-06 

2.00E-Ol 7.13E-03 I. 64E-04 

3.00E-Ol 9.71E-03 B.29E-04 

4.00E-Ol 1.17E-02 2. 42E-03 

5.00E-Ol 1. 32E-02 S.28E-03 

6.00E-Ol 1.43E-02 9.61E-03 

7.00E-OI 1. S2E-02 I.SSE-02 

B.OOE-Ol 1.SBE-02 2.30E-02 

9.00E-Ol 1.63E-02 3. 19E-02 

I.OOE+OO I. 67E-02 I. 67E-02 4.2IE-02 4.21E-02 

2.00E+OO 1.23E-03 1.79E-02 1.3SE-Ol 1. 77E-Ol 

3.00E+OO 2.09E-04 1.BIE-02 1.14E-Ol 2.92E-Ol 

4.00E+OO 1. 42E-04 1. B3E-02 6.6SE-02 3. SBE-Ol 

S.OOE+OO 1.36E-04 I.B4E-02 3. 42E-02 3. 92E-Ol 

6.00E+OO 1.3SE-04 I.B6E-02 1.71E-02 4.09E-Ol 

7.00E+OO 1. 34E-04 1.B7E-02 8. 78E-03 4.18E-Ol 

B.OOE+OO 1.32E-04 1. BBE-02. 4.B4E-03 4. 23E-Ol 

9.00E+OO 1.31E-04 1.90E-02 2. 97E-03 4.26E-Ol 

1.OOE+OI 1.30E-04 1.91E-02 2.07E-03 4.2BE-Ol 

2.00E+Ol 1.20E-04 2.03E-02 1.09E-03 4.40E-Ol 

3.00E+Ol 1.llE-04 2.1SE-02 9.44E-04 4.S1E-Ol 

4.00E+Ol 1.02E-04 2.2SE-02 8.22E-04 4.S9E-Ol 

5.00E+Ol 9.40E-OS 2.3SE-02 7.1SE-04 4.67E-Ol 

6.00E+OI 8. 66E-OS 2. 44E-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol 7.99E-05 2. S2E-02 S.42E-04 4. 79E-OI 

B.OOE+OI 7. 37E-05 2.60E-02 4. 72E-04 4.B4E-Ol 

9.00E+OI 6.BIE-OS 2. 67E-02 4.11E-04 4.B9E-Ol 

1.OOE+02 6.30E-OS 2. 74E-02 3.5BE-04 4.93E-Ol 

2.00E+02 3. 23E-OS 3.19E-02 B.94E-OS S.12E-OI 

3.00E+02 2.l7E-05 3.4SE-02 2. 24E-OS S.17E-Ol 

4.00E+02 I.BIE-OS 3. 64E-02 S.59E-06 S.lBE-Ol 

S.OOE+02 1.6BE-OS 3. 82E-02 1.40E-06 5.IBE-OI 

6.00E+02 1.62E-OS 3. 98E-02 3.49E-07 5.IBE-OI 

7.00E+02 1.S8E-OS 4.14E-02 8. 73E-OB S.IBE-OI 

8.00E+02 1. SSE-OS 4.30E-02 2.IBE-OB S.18E-OI 

9.00E+02 1.SlE-OS 4.4SE-02 O.OOE+OO S.IBE-OI 

I.OOE+03 I. 49E-OS 4.60E-02 O.OOE+OO S.lBE-Ol 

2.00E+03 1. 22E-OS S.9SE-02 O.OOE+OO S.lBE-Ol 

4.00E+03 B.20E-06 7.96E-02 O.OOE+OO S.18E-0l 

5.00E+03 6. 73E-06 B.70E-02 O.OOE+OO S.lBE-OI 

8.00E+03 3.7IE-06 1.02E-Ol O.OOE+OO 5.18E-0l 

1.OOE+04 2.S0E-06 1.OBE-Ol O.OOE+OO S.18E-Ol 

B-290 
CLASS W AMAD = 1 KICRON HALFLIFE= 1.29E+02 DAYS 11:lULIUH 170 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6.7BE-02 2. 76E-Ol 2.34E-0l S.71E-02 6.36E-Ol 

2.00E-Ol 6.S0E-02' 2.6SE-OI 1.97E-Ol 1.OSE-OI 6.32E-Ol 

3.00E-Ol 6.29E-02 2. SSE-Ol 1.66E-Ol 1.4SE-Ol 6.29E-OI 

4.00E-Ol 6.l3E-02 2.47E-Ol 1.39E-Ol 1.7BE-Ol 6. 26E-Ol 

S.OOE-Ol 6.0lE-02 2.39E-Ol 1.17E-Ol 2.0SE-Ol 6.21E-0l 

6.00E-Ol S.92E-02 2.32E-Ol 9.B3E-02 2. 26E-Ol 6.l6E-Ol 

7.00E-Ol S.BSE-02 2.26E-Ol B.26E-02 2. 42E-0l 6.09E-0l 

B.OOE-Ol S.79E-02 2.20E-Ol 6. 94E-02 2.S3E-Ol 6.00E-Ol 

9.00E-Ol S.76E-02 2.lSE-Ol S.B4E-02 2.60E-0l S.9lE-Ol 

1.00E+OO S.73E-02 2.l0E-Ol 4.9lE-02 2. 64E-Ol S.BOE-Ol 

2.00E+OO S.6SE-02 1.7SE-Ol B.62E-03 2.01E-0l 4.42E-Ol 

3.00E+OO S.6SE-02 1.S7E-Ol 1.S2E-03 1.llE-Ol 3.27E-Ol 

4.00E+OO S.66E-02 1.47E-0l 2.67E-04 S.60E-02 2.60E-Ol 

S.OOE+OO 5. 66E-02 1.4lE-Ol 4. 69E-05 2. 77E-02 2.25E-Ol 

6.00E+OO 5. 67E-02 1.36E-Ol B.24E-06 1.42E-02 2.07E-Ol 

7.00E+OO 5.67E-02 1.33E-Ol 1. 45E-06 7.B3E-03 1.9BE-Ol 

B.OOE+OO S.6BE-02 1.30E-Ol 2.5SE-07 4.B2E-03 1.92E-Ol 

9.00E+OO 5.6BE-02 1.2BE-Ol 4.4BE-OB 3.3BE-03 1.BBE-Ol 

1.OOE+Ol 5. 69E-02 1.25E-Ol O.OOE+OO 2. 67E-03 1. B5E-Ol 

2.00E+Ol S.70E-02 1.04E-Ol O.OOE+OO 1.6BE-03 1. 63E-Ol 

3.00E+Ol 5. 66E-02 B.70E-02 O.OOE+OO 1.39E-03 1.45E-Ol 

4.00E+Ol S.59E-02 7. 26E-02 O.OOE+OO 1.14E-03 1.30E-Ol 

5.00E+Ol S.49E-02 6.05E-02 O.OOE+OO 9.43E-04 1.16E-Ol 

6.00E+Ol 5.36E-02 5.0SE-02 O.OOE+OO 7.7BE-04 I.05E-Ol 

7.00E+Ol 5. 22E-02 4.21E-02 O.OOE+OO 6. 42E-04 9.49E-02 

B.OOE+OI 5.06E-02 3.5lE-02 O.OOE+OO 5. 29E-04 B.62E-02 

9.00E+Ol 4.90E-02 2.92E-02 O.OOE+OO 4. 37E-04 7.B6E-02 

1.OOE+02 4. 72E-02 2. 44E-02 O.OOE+OO 3.60E-04 7.19E-02 

2.00E+02 3.0lE-02 3.92E-03 O.OOE+OO S.25E-05 3.40E-02 

3.00E+02 1.7BE-02 6. 26E-04 O.OOE+OO 7. 66E-06 1.B4E-02 

4.00E+02 1.03E-02 9.90E-OS O.OOE+OO 1.12E-06 1.04E-02 

5.00E+02 5.BBE-O) 1.S6E-OS O.OOE+OO 1. 63E-07 5.90E-03 

6.00E+02 3.37E-03 2. 44E-06 O.OOE+OO 2.3BE-OB 3.37E-03 

7.00E+02 1. 93E-03 3. BOE-07 O.OOE+OO O.OOE+OO 1. 93E-03 

B.OOE+02 1.lOE-03 5.B9E-OB O.OOE+OO O.OOE+OO 1.lOE-03 

9.00E+02 6.30E-04 O.OOE+OO O.OOE+OO O.OOE+OO 6.30E-04 

1.OOE+03 3.60E-04 O.OOE+OO O.OOE+OO O.OOE+OO 3.60E-04 

2.00E+03 1. 35E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1. 35E-06 

B-29J 
CLASS W .AHAD = 1 HICIlON HALFLIFE- 1.298+02 DAYS mULIUM 170 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 3. 14E-03 8.10E-06 

2.00E-01 5. 99E-03 1. 64E-04 

3.00E-01 8. 15E-03 8.28E-04 

4.00E-01 9. 78E-03 2. 42E-03 

5.00E-Ol 1.10E-02 5.26E-03 

6.00E-01 1.20E-02 9.58E-03 

7.00E-01 1.27E-02 1. 55E-02 

8.00E-01 1. 32E-02 2. 29E-02 

9.00E-01 1.36E-02 3. 18E-02 

1.00E+00 1.40E-02 1.40E-02 4. 19E-02 4. 19E-02 

2.00E+00 1.03E-03 1. 49E-02 1. 34E-Ol 1. 76E-01 

3.00E+00 1. 75E-04 1.50E-02 1. 12E-Ol 2. 87E-01 

4.00E+00 1. 19E-04 1.50E-02 6.50E-02 3.51E-01 

5.00E+00 1. 14E-04 1.51E-02 3. 32E-02 3. 82E-01 

6.00E+00 1. 12E-04 1.51E-02 1.65E-02 3. 96E-Ol 

7.00E+00 1.1OE-04 1.51E-02 8.45E-03 4.03E-01 

8.00E+00 1.09E-04 1. 52E-02 4. 63E-03 4.05E-01 

9.00E+00 1.07E-04 1. 52E-02 2. 83E-03 4.06E-01 

1.00E+Ol 1.06E-04 1.52E-02 1.96E-03 4.06E-01 

2.00E+Ol 9.28E-05 1. 54E-02 9. 74E-04 3. 95E-Ol 

3.001::+01 8. 13E-05 1.54E-02 8.03E-04 3. 83E-Ol 

4.00E+01 7. 13E-05 1. 53E-02 6. 62E-04 3.70E-01 

5.00E+Ol 6. 25E-05 1.52E-02 5.46E-04 3. 57E-Ol 

6.00E+Ol 5. 48E-05 1.50E-02 4.51E-04 3. 43E-01 

7.00E+01 4.81E-05 1.47E-02 3.72E-04 3.29E-01 

8.00E+01 4. 23E-05 1. 43E-02 3.07E-04 3. 15E-01 

9.00E+01 3.72E-05 1.40E-02 2.53E-04 3.0lE-01 

1.00E+02 3. 28E-05 1. 36E-02 2.09E-04 2. 87E-Ol 

2.00E+02 1.04E-05 9. 32E-03 3.04E-05 1.74E-Ol 

3.00E+02 4. 33E-06 5. 94E-03 4. 44E-06 1.03E-01 

4.00E+02 2. 17E-06 3.70E-03 6.47E-07 5. 99E-02 

5.00E+02 1. 19E-06 2. 28E-03 9. 44E-08 3.50E-02 

6.00E+02 6.71E-07 1.40E-03 1.38E-08 2.04E-02 

7.00E+02 3. 82E-07 8. 54E-04 O.OOE+OO 1. 19E-02 

8.00E+02 2. 18E-07 5.20E-04 O.OOE+OO 6.95E-03 

9.00E+02 1. 25E-07 3. 16E-04 O.OOE+OO 4.05E-03 

1.00E+03 7. 14E-08 1.92E-04 O.OOE+OO 2. 36E-03 

B-292 
CLASS W .AHAD = 1 MICRON STABLE YTrERB IUM 173 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 54E-02 2. 76E-01 2.35E-01 5.72E-02 6.34E-01 

2.00E-01 6.02E-02 2. 65E-01 1. 97E-01 1.05E-01 6. 28E-01 

3.00E-01 5.61E-02 2. 56E-01 1.66E-01 1.46E-Ol 6.23E-01 

4.00E-01 5. 27E-02 2.47E-01 1. 39E-01 1.79E-01 6. 18E-01 

5.00E-01 5.0lE-02 2.40E-01 1. 17E-01 2.06E-01 6. 13E-01 

6.00E-01 4.80E-02 2. 33E-01 9. 86E-02 2.27E-01 6.06E-01 

7.00E-01 4. 63E-02 2.27E-01 8.29E:-02 2.43E-01 5.99E-01 

8.00E-01 4.50E-02 2.21E-01 6. 97E-02 2. 54E-01 5.90E-01 I 9.00E-01 4.39E-02 2. 16E-01 5.86E-02 2.61E-01 5.80E-01 

1.00E+00 4.31E-02 2. l1E-Ol 4. 93E-02 2. 65E-01 5.68E-01 

2.00E+00 4.03E-02 1.77E-01 8.72E-03 2.03E-01 4.30E-01 

3.00E+00 4.02E-02 1.60E-01 1. 54E-03 1. 13E-01 3. 15E-01 

4.00E+00 4.03E-02 1.50E-01 2.72E-04 5.72E-02 2.48E-01 

5.00E+00 4.05E-02 1.45E-01 4. 82E-05 2. 85E-02 2. 14E-01 

6.00E+00 4.07E-02 1.41E-01 8.51E-06 1.47E-02 1.96E-01 

7.00E+QO 4.09E-02 1. 38E-01 1. 51E-06 8. 14E-03 1.87E-01 

8.00E+00 4. 11E-02 1.36E-01 2.66E-07 5.04E-03 1. 82E-01 

9.00E+00 4. 13E-02 1.34E-01 4.70E-08 3. 55E-03 1. 79E-01 

1.00E+01 4. 15E-02 1.32E-01 O.OOE+OO 2. 82E-03 1.76E-01 

2.00E+01 4. 35E-02 1. 16E-01 O.OOE+OO 1.87E-03 1. 62E-01 

3.00E+01 4.54E-02 1.02E-01 O.OOE+OO 1.63E-03 1.49E-01 

4.00E+01 4. 72E-02 9.01E-02 O.OOE+OO 1.42E-03 1.39E-01 

5.00E+01 4.89E-02 7.93E-02 O.OOE+OO 1.23E-03 1.29E-01 

6.00E+01 5.03E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.21E-01 7~00E+01 5. 17E-02 6. 14E-02 O.OOE+OO 9.36E-04 1. 14E-01 

8.00E+01 5. 29E-02 5.40E-02 O.OOE+OO 8. 15E-04 1.08E-01 

9.00E+01 5.40E-02 4. 75E-02 O.OOE+OO 7.09E-04 1.02E-01 

1.00E+02 5. 49E-02 4. 18E-02 O.OOE+OO 6. 17E-04 9. 73E-02 

2.00E+02 5. 98E-02 1. 15E-02 O.OOE+OO 1.54E-04 7. 15E-02 

3.00E+02 6.06E-02 3. 15E-03 O.OOE+OO 3. 86E-05 6. 38E-02 

4.00E+02 6.00E-02 8. 55E-04 O.OOE+OO 9.65E-06 6.09E-02 

5.00E+02 5.90E-02 2. 31E-04 O.OOE+OO 2.41E-06 5. 92E-02 

6.00E+02 5.79E-02 6. 19E-05 O.OOE+OO 6.03E-07 5. 79E-02 

7.00E+02 5. 68E-02 1. 65E-05 O.OOE+OO 1.51E-07 5. 68E-02 

8.00E+02 5.57E-02 4.40E...;.06 O.OOE+OO 3.77E-08 5.57E-02 

9.00E+02 5. 46E-02 1. 16E-06 O.OOE+OO O.OOE+OO 5.46E-02 

1.00E+03 5.35E-02 3.08E-07 O.OOE+OO O.OOE+OO 5. 35E-02 

2.00E+03 4. 39E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 39E-02 

4.00E+03 2.95E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.95E-02 

5.00E+03 2. 42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 42E-02 

7.00E+03 1. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.63E-02 

8.00E+03 1. 34E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1. 34E-02 

1.00E+04 9.00E-03 O.OOE+OO O.OOE+OO O.OOE+OO 9.00E-03 

2.00E+04 1. 24E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.24E-03 

B-293 
CLASS W AMAD ... 1 MICRON STABLE YTTERBIUM 173 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol S.SBE-03 B.lOE-06 

2.00E-Ol 1.09E-02 1. 64E-04 

3.00E-Ol 1. SlE-02 B.29E-04 

4.00E-Ol 1. BSE-02 2. 42E-03 

5.00E-Ol 2.l2E-02 5.2BE-03 

6.00E-Ol 2. 34E-02 9.6lE-03 

7.00E-Ol 2.5lE-02 1.5SE-02 

B.OOE-Ol 2. 65E-02 2.30E-02 

9.00E-0l 2.76E-02 3.l9E-02 

1.OOE+OO 2. BSE-02 2. BSE-02 4.2lE-02 4.2lE-02 

2.00E+OO 3. 36E-03 3.lBE-02 1.35E-Ol 1.77E-Ol 

3.00E+OO 6.3BE-04 3.2SE-02 1.14E-Ol 2. 92E-Ol 

4.00E+OO 3. 46E-04 3.2BE-02 6.6SE-02 3.S8E-Ol 

5.00E+OO 3.09E-04 3.3lE-02 3. 42E-02 3. 92E-Ol 

6.00E+OO 2. 99E-04 3. 34E-02 1.71E-02 4.09E-Ol 

7.00E+OO 2. 93E-04 3. 37E-02 8.7BE-03 4.18E-Ol 

8.00E+OO 2.B7E-04 3.40E-02 4.B4E-03 4.23E-Ol 

9.00E+OO 2.BlE-04 3. 43E-02 2. 97E-03 4. 26E-OI 

1.OOE+OI 2. 76E-04 3.46E-02 2.07E-03 4.2BE-Ol 

2.00E+Ol 2. 34E-04 3.7lE-02 1.09E-03 4.40E-OI 

3.00E+Ol 2.04E-04 3.93E-02 9.44E-04 4.SlE-Ol 

4.00E+Ol 1.B2E-04 4.l2E-02 B.22E-04 4.S9E-OI 

S.OOE+Ol 1.63E-04 4. 29E-02 7.lSE-04 4.67E-Ol 

6.00E+Ol 1.4BE-04 4. 44E-02 6. 23E-04 4. 74E-OI 

7.00E+Ol I. 34E-04 4.5BE-02 5. 42E-04 4.79E-Ol 

8.00E+Ol 1. 22E-04 4.71E-02 4.72E-04 4.84E-Ol 

9.00E+Ol 1.l1E-04 4. B2E-02 4.11E-04 4. 89E-OI 

1.OOE+02 1.OlE-04 4. 93E-02 3.SBE-04 4. 93E-OI 

2.00E+02 4.l4E-05 S.59E-02 8.94E-05 S.12E-Ol 

3.00E+02 2.l2E-05 S.BBE-02 2. 24E-OS 5.17E-Ol 

4.00E+02 1.46E-OS 6.0SE-02 S.S9E-06 S.18E-Ol 

S.OOE+02 1.2SE-OS 6.l9E-02 1.40E-06 5.18E-Ol 

6.00E+02 1.17E-OS 6.3IE-02 3.49E-07 S.IBE-Ol 

7.00E+02 1.l3E-OS 6. 42E-02 8. 73E-08 S.18E-Ol 

B.OOE+02 1.1OE-OS 6.S3E-02 2.lBE-OB S.IBE-Ol 

9.00E+02 I.08E-OS 6. 64E-02 O.OOE+OO S.18E-Ol 

1.OOE+03 1.06E-OS 6.7SE-02 O.OOE+OO 5.lBE-OI 

2.00E+03 B.69E-06 7.71E,..02 O.OOE+OO S.lBE-OI 

4.00E+03 S.BSE-06 9.14E-02 O.OOE+OO S.IBE-OI 

B.OOE+03 2.6SE-06 I.OBE-OI O.OOE+OO 5.18E-OI 

I.OOE+04 1.7BE-06 1.12E-01 O.OOE+OO S.18E-OI 

2.00E+04 2. 46E-07 1.20E-01 O.OOE+OO S.lBE-01 

B-294 
CLASS W AHA» = 1 MICRON STABLE LUTETIUM 175 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 63E-02 2.76E-Ol 2. 35E-Ol 5 .. 72E-02 6. 34E-Ol 

2.00E-Ol 6.20E-02 2. 65E-Ol 1. 97E-Ol l.OSE-Ol 6.30E-Ol 

3.00E-Ol 5. 85E-02 2. S6E-Ol 1.66E-OI I.46E-0l 6.26E-Ol 

4.00E-Ol S.57E-02 2.47E-Ol 1. 39E-OI 1. 79E-Ol 6.2IE-Ol 

S.OOE-Ol S.3SE-02 2.40E-Ol l.l7E-0l 2.06E-Ol 6.16E-Ol 

6.00E-Ol S.17E-02 2.33E-Ol 9. 86E-02 2. 27E-Ol 6.lOE-OI 

7.00E-OI 5.03E-02 2.27E-Ol 8.29E-02 2.43E-OI 6.02E-Ol 

B.OOE-Ol 4. 92E-02 2.2lE-OI 6. 97E-02 2.S4E-OI S.94E-OI 

9.00E-Ol 4.83E-02 2.16E-0l 5.86E-02 2.6lE-0l 5. 84E-OI 

1.00E+OO 4. 76E-02 2.llE-Ol 4. 93E-02 2. 65E-Ol 5. 73E-OI 

2.00E+OO 4.S4E-02 1.77E-OI 8. 72E-03 2.03E-Ol 4. 35E-Ol 

3.00E+OO 4. 54E-02 1.60E-OI I.S4E-03 1. 13E-Ol 3.20E-Ol 

4.00E+OO 4.57E-02 1. SOE-Ol 2.72E-04 5.72E-02 2.53E-Ol 

5.00E+OO 4.60E-02 1.45E-OI 4. 82E-05 2.8SE-02 2.l9E-OI 

6,.{>OE+OO 4. 62E-02 1.41E-0l 8.5IE-06 1. 47E-02 2.02E-Ol 

7.00E+OO 4.6SE-02 1. 38E-Ol 1.51E-06 8. 14E-03 I. 93E-Ol 

8.00E+OO 4.6BE-02 1.36E-0l 2.66E-07 5.04E-03 1.8BE-0l 

9.00E+OO 4.71E-02 1. 34E-Ol 4.70E-08 3.SSE-03 1.8SE-Ol 

1.00E+Ol 4. 73E-02 1.32E-0l O.OOE+OO 2. 82E-03 1. 82E-OI 

2.00E+Ol S.OOE-02 1.16E-Ol O.OOE+OO 1. 87E-03 1. 68E-Ol 

3.00E+Ol 5. 23E-02 1.02E-Ol O.OOE+OO 1.63E-03 I.S6E-0l 

4.00E+Ol 5.4SE-02 9.01E-02 O.OOE+OO 1. 42E-03 1. 46E-Ol 

5.00E+Ol 5.6SE-02 7. 93E-02 O.OOE+OO 1.23E-03 1.37E-OI 

6.00E+Ol 5. 82E-02 6. 98E-02 O.OOE+OO 1.07E-03 1.29E-OI 

7.00E+OI S.9BE-02 6. 14E-02 O.OOE+OO 9.36E-04 l.22E-OI 

8.00E+Ol 6.l2E-02 5.40E-02 O.OOE+OO 8. 15E-04 I. 16E-OI 

9.00E+OI 6. 24E-02 4.7SE-02 O.OOE+OO 7.09E-04 l.llE-OI 

1.00E+02 6.36E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1.06E-Ol 

2.00E+02 6. 93E-02 1.ISE-02 O.OOE+OO 1. S4E-04 B.I0E-02 

3.00E+02 7.02E-02 3.1SE-03 O.OOE+OO 3. 86E-OS 7. 34E-02 

4.00E+02 6.95E-02 8. SSE-04 O.OOE+OO 9.6SE-06 7.04E-02 

S.OOE+02 6.84E-02 2. 31E-04 O.OOE+OO 2.41E-06 6. 86E-02 

6.00E+02 6.71E-02 6. 19E-OS O.OOE+OO 6.03E-07 6.71E-02 

7.00E+02 6.5BE-02 l.65E-05 O.OOE+OO l.SIE-07 6.S8E-02 

8.00E+02 6.4SE-02 4.40E-'06 O.OOE+OO 3. 77E-OB 6.4SE-02 

9.00E+02 6. 32E-02 1. 16E-06 O.OOE+OO O.OOE+OO 6. 32E-02 

I.OOE+03 6.20E-02 3.08E-07 O.OOE+OO O.OOE+OO 6.20E-02 

2.00E+03 S.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.09E-02 

4.00E+03 3.42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 42E-02 

S.OOE+03 2.BIE-02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 81E-02 

7.00E+03 1.89E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.89E-02 

8.00E+03 I.SSE-02 O.OOE+OO O.OOE+OO O.OOE+OO I.SSE-02 

1.00E+04 1.04E-02 O~ OOE+OO O.OOE+OO O.OOE+OO 1.04E-02 

2.00E+04 1. 44E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 44E-03 

B-29S 
CLASS V AHA» = 1 MICRON STABLE IJJTETIUM 115 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4. 69E-03 8.l0E-06 

2.00E-Ol 9.l6E-03 1. 64E-04 

3.00E-Ol 1. 27E-02 8. 29E-04 

4.00E-Ol 1. 56E-02 2.42E-03 

5.00E-Ol 1. 78E-02 5. 28E-03 

6.00E-Ol 1. 97E-02 9.61E-03 

7.00E-Ol 2.l1E-02 1.55E-02 

8.00E-Ol 2. 23E-02 2.30E-02 

9.00E-Ol 2. 32E-02 3.19E-02 

1.OOE+OO 2. 39E-02 2. 39E-02 4.2lE-02 4.21E-02 

2.00E+OO 2. 78E-03 2. 67E-02 1.35E-Ol 1.77E-Ol 

3.00E+OO 4.90E-04 2.72E-02 1.14E-Ol 2. 92E-Ol 

4.00E+OO 2. 47E-04 2. 75E-02 6. 65E-02 3.58E-Ol 

S.OOE+OO 2.19E-04 2. 77E-02 3. 42E-02 3. 92E-OI 

6.00E+OO 2.13E-04 2. 79E-02 1.7lE-02 4.09E-Ol 

7.00E+OO 2.lOE-04 2.8lE-02 8. 78E-03 4.l8E-Ol 

8.00E+OO 2.07E-04 2. 83E-02 4. 84E-03 4. 23E-Ol 

9.00E+OO 2.04E-04 2. 85E-02 2. 97E-03 4.26E-Ol 

1.OOE+OI 2.02E-04 2. 87E-02 2.07E-03 4.28E-Ol 

2.00E+Ol 1.80E-04 3.06E-02 1.09E-03 4.40E-Ol 

3.00E+Ol 1. 63E-04 3. 23E-02 9. 44E-04 4.SlE-Ol 

4.00E+OI I. 48E-04 3. 39E-02 8.22E-04 4.S9E-Ol 

5.00E+OI 1. 35E-04 3. 53E-02 7.15E-04 4.67E-Ol 

6.00E+Ol 1. 23E-04 3. 66E-02 6.23E-04 4. 74E-Ol 

7.00E+Ol 1.12E-04 3.77E-02 5.42E-04 4.79E-Ol 

8.00E+Ol 1.02E-04 3. 88E-02 4. 72E-04 4. 84E-Ol 

9.00E+Ol 9. 35E-OS 3. 98E-02 4.IIE-04 4. 89E-Ol 

1.OOE+02 8. SSE-OS 4.06E-02 3.S8E-04 4. 93E-OI 

2.00E+02 3.77E-05 4. 64E-02 8. 94E-05 5.12E-Ol 

3.00E+02 2.13E-05 4. 92E-02 2. 24E-OS S.17E-Ol 

4.00E+02 1.60E-05 5.l0E-02 5. 59E-06 5.18E-Ol 

5.00E+02 l.42E-Os 5.2sE-02 1.40E-06 S.18E-Ol 

6.00E+02 l.3sE-05 S.39E-02 3. 49E-07 s.18E-Ol 

7.00E+02 1.3lE-Os s.s2E-02 8. 73E-OS s.18E-Ol 

8.00E+02 I. 28E-Os s.6SE-02 2.18E-OS s.18E-Ol 

9.00E+02 1.2sE-OS s.77E-02 O.OOE+OO s.18E-OI 

I.OOE+03 I. 23E-Os 5.90E-02 O.OOE+OO s.18E-Ol 

2.00E+03 1.OIE-Os 7.0IE-02 O.OOE+OO 5.18E-Ol 

4.00E+03 6. 78E-06 8.68E-02 O.OOE+OO s.18E-OI 

8.00E+03 3.07E-06 I.OsE-OI O.OOE+OO S.18E-OI 

I.OOE+04 2.07E-06 1.IlE-OI O.OOE+OO S.18E-0l 

B-296 
CLASS W AHA» == 1 MICRON STABLE HAFNIUM: 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7.07E-02 2.76E-Ol 2.3SE-Ol S.71E-02 6. 39E-Ol 

2.00E-Ol 7.05E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6.3BE-Ol 

3.00E-Ol 7.03E-02 2.S6E-Ol 1.66E-Ol 1.4SE-Ol 6. 37E-Ol 

4.00E-Ol 7.01E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.3SE-Ol 

5.00E-Ol 6. 99E-02 2.40E-Ol 1.17E-0l '2.05E-Ol 6.32E-Ol 

6.00E-Ol 6. 96E-02 2. 33E-Ol 9.B6E-02 2. 26E-Ol 6.2BE-Ol 

7.00E-0l 6. 94E-02 2. 27E-Ol B.29E-02 2.42E-0l 6.21E-Ol 

B.OOE-Ol 6. 92E-02 2.2lE-Ol 6. 97E-02 2. 54E-Ol 6.13E-Ol 

9.00E-Ol 6.90E-02 2.l6E-Ol S.B6E-02 2.6lE-Ol 6.04E-Ol 

1.OOE+OO 6.B7E-02 2.llE-Ol 4. 93E-02 2. 65E-Ol S.94E-:-Ql 

2.00E+OO 6. 63E-02 1. 77E-Ol B.72E-03 2.03E-Ol 4.SSE-Ol 

3.00E+OO 6.4lE-02 1.60E-Ol 1. 54E-03 1.BE-Ol 3. 39E-Ol 

4.00E+OO 6.20E-02 1.50E-Ol 2.72E-04 S.71E-02 2.70E-Ol 

S.OOE+OO 6.0lE-02 1.4SE-Ol 4.B2E-05 2.B4E-02 2. 33E-Ol 

6.00E+OO 5.B4E-02 1.41E-Ol B.SIE-06 1. 46E-02 2.14E-0l 

7.00E+OO S.69E-02 1.3BE-Ol 1.SlE-06 8.l2E-03 2.03E-ol 

B.OOE+OO 5. 56E-02 1.36E-Ol 2.66E-07 5.03E-03 1.96E-Ol 

9.00E+OO S.44E-02 1. 34E-Ol 4.70E-OB 3.S4E-03 1. 92E-Ol 

1.OOE+Ol S.33E-02 1. 32E-Ol O.OOE+OO 2. BlE-03 1.BBE-Ol 

2.00E+Ol 4. 76E-02 1.16E-Ol O .. OOE+OO 1.B7E-03 1. 66E-Ol 

3.00E+Ol 4. 65E-02 1.02E-Ol O.OOE+OO 1.63E-03 1.SOE-Ol 

4.00E+Ol 4.71E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1. 39E-Ol 

5.00E+Ol 4.BlE-02 7.93E-02 O.OOE+OO 1.23E-03 1. 29E-Ol 

6.00E+Ol 4. 93E-02 6.9BE-02 O.OOE+OO 1.07E-03 1.20E-Ol 

7.00E+Ol 5.04E-02 6.14E-02 O.OOE+OO 9.34E-04 1.BE-Ol 

13.00E+Ol 5.l4E-02 5.40E-02 O.OOE+OO B.13E-04 1.06E-Ol 

9.00E+Ol 5. 24E-02 4.75E-02 O.OOE+OO 7.0BE-04 1.OlE-Ol 

1.OOE+02 S.32E-02 4.1BE-02 O.OOE+OO 6.l6E-04 9.S6E-02 

2.00E+02 S.7BE-02 1.l5E-02 O.OOE+OO 1.S4E-04 6.9SE-02 

3.00E+02 5.B9E-02 3.lSE-03 O.OOE+OO 3.B5E-OS 6.2lE-02 

4.00E+02 5.BBE-02 B.55E-04 O.OOE+OO 9.63E-06 S.97E-02 

5.00E+02 5.B5E-02 2.3lE-04 O.OOE+OO 2.4lE-06 5.B7E-02 

6.00E+02 5. BOE-02 6.l9E-OS O.OOE+OO 6.02E-07 5.BlE-02 

7.00E+02 5.7SE-02 1. 65E-OS O.OOE+OO 1.SOE-07 S.75E-02 

B.OOE+02 S.70E-02 4.40E-06 O.OOE+OO 3. 76E-OB S.70E-02 

9.00E+02 S.65E-02 1.16E-06 O.OOE+OO O.OOE+OO S.65E-02 

1.OOE+03 S.61E-02 3.0BE-07 O.OOE+OO O.OOE+OO 5.61E-02 

2.00E+03 5.14E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5.l4E-02 

4.00E+03 4. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.32E-02 

5.00E+03 3. 96E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 96E-02 

7.00E+03 3.33E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 33E-02 

B.OOE+03 3.06E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.06E-02 

1.OOE+04 2. 57E-02 O.OOE+OO O.OOE+OO O.OOE+OO 2.S7E-02 

2.00E+04 1.OBE-02 O.OOE+OO O.OOE+OO O'.OOE+OO 1.OBE-02 

B-297 
CLASS W AKAD :;:: 1 MICRON STABLE HAFNIUM 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEHIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUHULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3.00E-04 8.10E-06 

2.00E-Ol 6.47E-04 1.64E-04 

3.00E-Ol 9.92E-04 8.28E-04 

4.00E-Ol 1. 33E-03 2. 42E-03 

5.00E-Ol 1.67E-03 5.27E-03 

6.00E-Ol 2.01E-03 9.61E-03 

7.00E-01 2.34E-03 1.55E-02 

8.00E-01 2. 67E-03 2.30E-02 

9.00E-01 3.00E-03 3. 19E-02 

1.00E+00 3. 33E-03 3.33£-03 4.21E-02 4. 21E-02 

2.00E+00 3.lOE-03 6.43E-03 1.35E-01 1.77E-01 

3.00E+00 2. 84E-03 9.27E-03 1. 14E-Ol 2.91E-01 

4.00E+00 2.60E-03 1.19E-02 6.63£-02 3.58E-01 

5.00E+00 2. 38E-03 1.43E-02 3.41E-02 3. 92E-Ol 

6.00E+00 2. 18E-03 1. 64E-02 1.71E-02 4.09E-Ol 

7.00E+00 2.00E-03 1. 84E-02 8. 76E-03 4. 18E-Ol 

8.00E+00 1.83E-03 2.03E-02 4.83E-03 4.22E-01 

9.00E+00 1. 68E-03 2. 19E-02 2. 96E-03 4.25E-Ol 

1.00E+Ol 1.55E-03 2.35E-02 2.06E-03 4.27E-01 

2.00E+01 7. 19E-04 3. 38E-02 1.08E-03 4.40E-01 

3.00E+Ol 3. 98E-04 3. 89E-02 9.42E-04 4.50E-Ol 

4.00E+01 2. 67E-04 4.21E-02 8.20E-04 4. 58E-Ol 

5.00E+01 2.07E-04 4.44E-02 7.14E-04 4.66E-01 

6.00E+Ol 1.75E-04 4. 63E-02 6.22E-04 4. 73E-01 

7.00E+01 1.54E-04 4. 79E-02 5.41E-04 4. 78E-01 

8.00E+01 1. 38E-04 4. 94E-02 4. 71E-04 4. 84E-01 

9.00E+01 1. 24E-04 5.07E-02 4.10E-04 4.88E-01 

1.00E+02 1. 12E-04 5. 18E-02 3.57E-04 4. 92E-Ol 

2.00E+02 4.05E-05 5. 88E-02 8. 93E-05 5. 11E-01 

3.00E+02 1. 62E-05 6. 14E-02 2. 23E-05 5. 16E-01 

4.00E+02 8.41E-06 6.26E-02 5.58E-06 5.17E-Ol 

5.00E+02 6.03E-06 6.33E-02 1.39E-06 5. 17E-01 

6.00E+02 5.30E-06 6.38E-02 3. 49E-07 5. 17E-01 

7.00E+02 5.06E-06 6.43E-02 8. 72E-08 5. 17E-Ol 

8.00E+02 4.96E-06 6.48E-02 2. 18E-08 5. 17E-01 

9.00E+02 4.90E-06 6.53E-02 O.OOE+OO 5.17E-01 

1.00E+03 4. 86E-06 6. 58E-02 O.OOE+OO 5. 17E-01 

2.00E+03 4.45E-06 7.05E-02 O.OOE+OO 5. 17E-01 

4.00E+03 3. 74E-06 7.86E-02 O.OOE+OO 5. 17E-01 

8.00E+03 2. 65E-06 9. 13E-02 O.OOE+OO 5. 17E-Ol 

1.00E+04 2.23E-06 9. 62E-02 O.OOE+oo 5.17E-01 

B-298 
CLASS W AMAD = 1 MICRON HALFLIFE= 4.24K+01 DAYS HAFNIUM 181 

TIHE AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.06E-02 2. 76E-Ol 2. 34E-Ol 5.7lE-02 6. 38E-Ol 

2.00E-Ol 7.03E-02 2.64E-Ol 1.97E-Ol 1.05E-Ol 6. 36E-Ol 

3.00E-Ol 7.00E-02 2.54E-Ol 1.65E-Ol 1.45E-Ol 6.34E-Ol 

4.00E-Ol 6.96E-02 2. 46E-Ol 1. 39E-Ol 1. nE-OI 6.31E-Ol 

5.00E-Ol 6.93E-02 2.38E-Ol 1. 16E-Ol 2.04E-Ol 6.27E-Ol 

6.00E-Ol 6.90E-02 2.3IE-Ol 9.77E-02 2. 24E-OI 6.21E-Ol 

7.00E-Ol 6. 86E-02 2. 24E-Ol 8.20E-02 2.40E-Ol 6. 14E-Ol 

8.00E-OI 6.83E-02 2.18E-Ol 6.8BE-02 2.50E-Ol 6.06E-Ol 

9.00E-Ol 6.80E-02 2.l2E-Ol 5.78E-02 2. 57E-Ol 5.95E-0l 

1.00E+OO 6.76E-02 2.07E-Ol 4. 85E-02 2.6lE-Ol 5. 84E-Ol 

2.00E+OO 6.42E-02 1.72E-Ol 8.44E-03 1.97E-Ol 4.4lE-Ol 

3.00E+OO 6.10E-02 1. 52E-Ol 1.47E-03 1.08E-Ol 3.22E-Ol 

4.00E+OO 5.8lE-02 1.4lE-0l 2.55E-04 5. 35E-02 2. 53E-Ol 

5.00E+OO 5. 54E-02 1.33E-Ol 4.44E-05 2. 62E-02 2.l5E-Ol 

6.00E+OO 5.30E-02 I.28E-OI 7. 72E-06 1.33E-02 1.94E-Ol 

7.00E+OO 5.0BE-02 1.23E-Ol 1. 34E-06 7.24E-03 1.BIE-OI 

8.00E+OO 4.88E-02 1.19E-Ol 2.33E-07 4.41E-03 1.72E-Ol 

9.00E+OO 4. 69E-02 1.16E-Ol 4.06E-08 3.06E-03 1.66E-OI 

1.00E+Ol 4. 53E-02 1.l2E-OI O.OOE+OO 2. 39E-03 1.60E-Ol 

2.00E+Ol 3. 43E-02 8. 38E-02 O.OOE+OO 1.35E-03 1.19E-Ol 

3.00E+Ol 2.85E-02 6.26E-02 O.OOE+OO 9.96E-04 9.21E-02 

4.00E+Ol 2. 45E-02 4. 68E-02 O.OOE+OO 7.36E-04 7.20E-02 

5.00E+Ol 2. 12E-02 3.50E-02 O.OOE+OO 5. 44E-04 5.68E-02 

6.00E+Ol 1. 85E-02 2. 62E-02 O.OOE+OO 4.02E-04 4.50E-02 

7.00E+Ol 1.60E-02 1.95E-02 O.OOE+OO 2. 97E-04 3.59E-02 

8.00E+Ol 1. 39E-02 1. 46E-02 O.OOE+OO 2.20E-04 2.B7E-02 

9.00E+OI 1.20E-02 1.09E-02 O.OOE+OO 1. 63E-04 2.3lE-02 

1.00E+02 1.04E-02 B.15E-03 O.OOE+OO 1.20E-04 1. 86E-02 

2.00E+02 2.20E-03 4.3BE-04 O.OOE+OO 5.86E-06 2.64E-03 

3.00E+02 4. 36E-04 2. 34E-05 O.OOE+OO 2.B6E-07 4.60E-04 

4.00E+02 8.51E-05 1.24E-06 O.OOE+OO 1. 39E-OB 8. 63E-05 

5.00E+02 1.65E-05 6.50E-08 O.OOE+OO O.OOE+OO 1. 66E-05 

6.00E+02 3. 19E-06 O.OOE+OO O.OOE+OO O.OOE+OO 3. 19E-06 

7.00E+02 6.17E-07 O.OOE+OO O.OOE+OO O.OOE+OO 6. 17E-07 

8.00E+02 1.19E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1. 19E-07 

9.00E+02 2.30E-OB O.OOE+OO O.OOE+OO O.OOE+OO 2.30E-08 

B-299 
CLASS W AMAD = 1 KIeRON HALFLIFB= 4.24£+01 DAYS HA¥IIIUH 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-ROUR ACCUMULATED 24-ROUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E.,..,01 2. 99E-04 B.09E-06 

2.00E .... Ol 6. 45E-04 1. 63E-04 

3.00E-Ol 9.B7E-04 B.24E-04 

4.00E-Ol 1. 33E-03 2.40E-03 

5.00E-Ol 1.66E-03 5. 23E-03 

6.00E-Ol 1. 99E-03 9.51E-03 

7.00E-Ol 2. 32E-03 1. 53E-02 

B.OOE-Ol 2.64E-03 2. 27E-02 

9.00E-OI 2. 96E-03 3.14E-02 

1.00E+OO 3. 27E-03 3. 27E-03 4. 14E-02 4. 14E-02 

2.00E+OO 3.00E-03 6. 23E-03 1.31E-0l 1.72E-Ol 

3.00E+OO 2.70E-03 B.B3E-03 I.09E-0l 2. 77E-Ol 

4.00E+OO 2. 43E-03 1.11E-02 6.2IE-02 3. 35E-OI 

5.00E+OO 2.19E-03 1.31E-02 3.14E-02 3.6IE-OI 

6.00E+OO 1.97E-03 1. 49E-02 1.55E-02 3.7lE-OI 

7.00E+OO 1.7BE-03 1. 64E-02 7.BIE-03 3. 72E-Ol 

B.OOE+OO 1.6IE-03 1.7BE-02 4.24E-03 3.7lE-OI 

9.00E+OO 1.45E-03 I.B9E-02 2. 56E-03 3. 67E-Ol 

I.OOE+OI 1.31E-03 1.99E-02 1.75E-03 3. 63E-OI 

2.00E+Ol 5.IBE-04 2. 43E-02 7.BIE-04 3. 17E-Ol 

3.00E+0l 2. 44E-04 2.3BE-02 5.77E-04 2. 75E-Ol 

4.00E+OI 1.39E-04 2. 19E-02 4. 27E-04 2.3BE-Ol 

5.00E+Ol 9.16E-05 1. 96E-02 3. 15E-04 2.06E-Ol 

6.00E+OI 6. 56E-05 1. 74E-02 2. 33E-04 1.77E-OI 

7.00E+0l 4.90E-05 1. 53E-02 1. 72E-04 1.52E-OI 

B.OOE+Ol 3.72E-05 1. 33E-02 1. 27E-04 1.31E-OI 

9.00E+Ol 2.B4E-05 1. 16E-02 9. 42E-05 1.12E-0l 

1.00E+02 2.1BE-05 1.0IE-02 6. 96E-05 9. 59E-02 

2.00E+02 1.54E-06 2. 24E-03 3. 39E-06 1. 94E-02 

3.00E+02 1.20E-07 4. 55E-04 1. 65E-07 3.B2E-03 

4.00E+02 1. 22E-OB 9.04E-05 O.OOE+OO 7.47E-04 

B-300 
CLASS W AMAD = 1 MICRON STABLE TANTALUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.06E-02 2.76E-Ol 2. 35E-Ol 5.72E-02 6.39E-Ol 

2.00E-Ol 7.03E-02 2. 65E-Ol 1.97E-Ol 1.OSE-Ol 6.3BE-Ol 

3.00E-Ol 6.99E-02 2.56E-Ol 1.66E-Ol 1.4SE-Ol 6.37E-Ol 

4.00E-Ol 6. 96E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.3SE-Ol 

S.OOE-Ol 6. 92E-02 2.40E-Ol 1.17E-Ol 2.06E-0l 6.32E-Ol 

6.00E-Ol 6.B9E-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6.27E-Ol 

7.00E-0l 6. BSE-02 2. 27E-Ol B.29E-02 2. 43E-Ol 6.2lE-Ol 

8.00E-Ol 6. 82E-02 2.2lE-Ol 6. 97E-02 2.S4E-Ol 6.13E-Ol 

9.00E-Ol 6. 79E-02 2.16E-Ol S.B6E-02 2.61E-Ol 6.03E-Ol 

1.OOE+OO 6.7SE-02 2.11E-Ol . 4.93E-02 2.6SE-Ol S.93E-Ol 

2.00E+OO 6. 44E-02 1.77E-Ol 8. 72E-03 2.03E-Ol 4.S4E-Ol 

3.00E+OO 6.18E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3.36E-Ol 

4.00E+OO S.9SE-02 1.SOE-Ol 2.72E-04 S.72E-02 2.67E-Ol 

S.OOE+OO S.76E-02 1.4SE-Ol 4. 82E-OS 2.8SE-02 2.3lE-Ol 

6.00E+OO S.60E-02 1.4lE-Ol B. SlE-06 1. 47E-02 2.l1E-Ol 

7.00E-fOO S.46E-02 1.3BE-Ol 1.5lE-06 8.13E-03 2.0lE-0l 

8.00E+OO S.3SE-02 1.36E-Ol 2. 66E-07 S.03E-03 1.94E-0l 

9.00E+OO S.2SE-02 1. 34E-Ol 4.70E-OB 3. 54E-03 1.90E-Ol 

1.OOE+Ol S.17E-02 1. 32E-Ol O.OOE+OO 2.8lE-03 1.87E-0l 

2.00E+Ol 4.7BE-02 1.16E-Ol O.OOE+OO 1.87E-03 1. 66E-Ol 

3.00E+Ol 4.66E-02 1.02E-Ol O.OOE+OO 1. 63E-03 1. SlE-Ol 

4.00E+Ol 4.S7E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1. 37E-Ol 

S.OOE+Ol 4. 47E-02 7. 93E-02 O.OOE+OO 1.23E-03 1.2SE-Ol 

6.00E+Ol 4. 36E-02 6.9BE-02 O.OOE+OO 1.07E-03 1.14E-Ol 

7.00E+Ol 4. 24E-02 6.l4E-02 O.OOE+OO 9.3SE-04 1.05E-Ol 

8.00E+Ol 4.llE-02 S.40E-02 O.OOE+OO 8.l4E-04 9.S9E-02 

9.00E+Ol 3. 97E-02 4.7SE-02 O.OOE+OO 7.09E-04 B.79E-02 

1.OOE+02 3. 83E-02 4.l8E-02 O.OOE+OO 6.l7E-04 8.07E-02 

2.00E+02 2.4lE-02 1.lSE-02 O.OOE+OO 1.S4E-04 3. 58E-02 

3.00E+02 1. 37E-02 3.lSE-03 O.OOE+OO 3.B6E-OS 1.69E-02 

4.00E+02 7.32E-03 B. SSE-04 O.OOE+OO 9.64E-06 B.lBE-03 

S.OOE+02 3.80E-03 2.3lE-04 O.OOE+OO 2.4lE-06 4.04E-03 

6.00E+02 1. 94E-03 6.l9E-OS O.OOE+OO 6.03E-07 2.00E-03 

7.00E+02 9. 83E-04 1.6SE-OS O.OOE+OO 1.SlE-07 1.OOE-03 

8.00E+02 4.9SE-04 4.40E-06 O.OOE+OO 3. 77E-OB 4. 99E-04 

... 9.00E+02 2. 48E-04 1.16E-06 O.OOE+OO O.OOE+OO 2. 49E-04 . . 

' ",' ."" .:~ .- 1.OOE+03 1. 24E-04 3.0BE-07 O.OOE+OO O.OOE+OO 1.25E-04 

2.00E+03 1.22E-07 O.OOE+OO O.OOE+OO O.OOE+OO 1. 22E-07 

B-30l 
CLASS W AMAD = 1 MICRON STABLE TANTALUM 181 

TUIE AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.93E-04 S.lOE-06 

2.00E-Ol S.46E-04 1. 64E-04 

3.00E-Ol 1. 29E-03 S.29E-04 

4.00E-Ol 1. 73E-03 2. 42E-03 

S.OOE-Ol 2.l7E-03 S.2SE-03 

6.00E-Ol 2.S9E-03 9.6lE-03 

7.00E-Ol 3.0lE-03 1.SSE-02 

S.OOE-Ol 3.43E-03 2.30E-02 

9.00E-Ol 3.S4E-03 3.l9E-02 

1.OOE+OO 4. 24E-03 4. 24E-03 4.2lE-02 4.2lE-02 

2.00E+OO 3.7lE-03 7.9SE-03 1.3SE-Ol 1.77E-Ol 

3.00E+OO 3.20E-03 1.12E-02 1.14E-Ol 2. 92E-Ol 

4.00E+OO 2.7SE-03 1. 39E-02 6.64E-02 3.S8E-Ol 

S.OOE+OO 2.4lE-03 1. 63E-02 3.4lE-02 3. 92E-Ol 

6.00E+OO 2.llE-03 1.8SE-02 1.7lE-02 4.09E-Ol 

7.00E+OO 1.S5E-03 2.03E-02 S.77E-03 4.lSE-Ol 

S.OOE+OO 1.64E-03 2.l9E-02 4.83E-03 4.23E-Ol 

9.00E+OO 1. 45E-03 2. 34E-02 2. 96E-03 4. 26E-Ol 

1.OOE+Ol 1.30E-03 2. 47E-02 2.07E-03 4.2SE-Ol 

2.00E+Ol 6. 22E-04 3.3lE-02 1.08E-03 4.40E-Cl 

3.00E+Ol 4.S7E-04 3.S4E-02 9. 43E-04 4.S0E-Ol 

4.00E+Ol 4.4SE-04 4.30E-02 S.2lE-04 4.S9E-Ol 

S.OOE+Ol 4.2SE-04 4. 74E-02 ·7.lSE-04 4.67E-Ol 

6.00E+Ol 4.06E-04 S.lSE-02 6. 22E-04 4. 73E-Ol 

7.00E+Ol 3.SSE-04 S.SSE-02 5.42E-04 4. 7~E-Ol 

S.OOE+Ol 3. 69E-04 S.92E-02 4.72E-04 4. 84E-Ol 

9.00E+Ol 3. S2E-04 6.2SE-02 4.11E-04 4.SSE-Ol 

1.OOE+02 3. 34E-04 6. 63E-02 3. 57E-04 4. 92E-Ol 

2.00E+02 1.90E-04 9.l9E-02 S.94E-OS S.llE-Ol 

3.00E+02 1.02E-04 1.06E-Ol 2. 23E-05 S.16E-Ol 

4.00E+02 S.30E-OS 1.l4E-Ol S.S9E-06 S.17E-Ol 

5.00E+02 2.70E-05 l.17E-Ol 1.40E-06 S.lSE-Ol 

6.00E+02 1.37E-05 1.19E-Ol 3.49E-07 S.lSE-Ol 

7.00E+02 6.SSE-06 1.20E-Ol S.73E-OS S.18E-Ol 

S.OOE+02 3.4SE-06 1.2lE-Ol 2.lSE-OS S.lSE-Ol 

9.00E+02 1.73E-06 1.2lE-Ol O.OOE+OO 5.lSE-Ol 

1.OOE+03 S.66E-07 1.2lE-0l O.OOE+OO 5.lBE-Ol 

B-302 
CLASS W AHAD ,.. 1 KIClWR BALFLlFE= 1.15E+02 TANTALUM 182 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.06E-02 2. 76E-Ol 2.34E-Ol 5.71E-02 6.3BE-Ol 

2.00E-Ol 7.02E-02 2. 65E-Ol 1. 97E-Ol 1.05E-OI 6.37E-Ol 

3.00E-Ol 6.9BE-02 2. 55E-OI I.66E-Ol I.45E-Ol 6. 36E-Ol 

4.00E-OI 6. 94E-02 2.47E-OI 1. 39E-Ol I.7BE-Ol 6. 33E-Ol 

5.00E-Ol 6.90E-02 2. 39E-OI I.l7E-OI 2.05E-OI 6.30E-Ol 

6.00E-OI 6.B6E-02 2. 32E-Ol 9.B3E-02 2. 26E-OI 6. 25E-Ol 

7.00E-Ol 6.B3E-02 2.26E-Ol B.26E-02 2. 42E-OI 6.lBE-Ol 

B.OOE-Ol 6. 79E-02 2.20E-Ol 6. 94E-02 2. 53E-OI 6.lOE-Ol 

9.00E-Ol 6. 75E-02 2.14E-OI 5.B3E-02 2.60E-Ol 6.00E-Ol 

I.OOE+OO 6.71E-02 2.09E-OI 4.90E-02 2. 64E-Ol 5.B9E-Ol 

2.00E+OO 6.37E-02 l.75E-Ol B.6IE-03 2.0lE-Ol 4.4BE-Ol 

3.00E+OO 6.07E-02 1. 57E-Ol I.5lE-03 I.llE-OI 3.30E-OI 

4.00E+OO 5.BlE-02 l.47E-OI 2.66E-04 5.5BE-02 2.6lE-0l 

5.00E+OO 5. 59E-02 1.40E-OI 4. 67E-05 2. 76E-02 2.24E-Ol 

6.00E+OO 5.40E-02 1.36E-Ol B.2lE-06 1.4lE-02 2.04E-Ol 

7.00E+OO 5.24E-02 1.32E-OI 1. 44E-06 7. 79E-03 1. 93E-Ol 

B.OOE+OO 5.l0E-02 1. 29E-Ol 2. 54E-07 4. BOE-03 I.B5E-Ol 

9.00E+OO 4. 97E-02 1. 27E-Ol 4. 45E-OB 3. 36E-03 1. BOE-Ol 

I.OOE+OI 4.B7E-02 1.24E-Ol O.OOE+OO 2. 65E-03 I.76E-Ol 

2.00E+Ol 4. 24E-02 1.03E-OI O.OOE+OO I.66E-03 1.47E-OI 

3.00E+Ol 3.B9E-02 B.54E-02 O.OOE+OO I.36E-03 I.26E-Ol 

4.00E+Ol 3. 59E-02 7.0BE-02 O.OOE+OO 1.11E-03 1.OBE-Ol 

5.00E+Ol 3.3IE-02 5. B6E-02 O.OOE+OO 9.l3E-04 9.26E-02 

6.00E+Ol 3.04E-02 4.B6E-02 O.OOE+OO 7.4BE-04 7. 97E-02 

7.00E+Ol 2.7BE-02 4.03E-02 O.OOE+OO 6.l3E-04 6.B7E-02 

B.OOE+Ol 2. 54E-02 3. 33E-02 O.OOE+OO 5.03E-04 5. 92E-02 

9.00E+Ol 2.3IE-02 2. 76E-02 O.OOE+OO 4.l2E-04 5.11E-02 

1.OOE+02 2.l0E-02 2. 29E-02 O.OOE+OO 3.3BE-04 4. 42E-02 

2.00E+02 7. 23E-03 3. 45E-03 O.OOE+OO 4. 62E-05 I.07E-02 

3.00E+02 2. 24E-03 5.17E-04 O.OOE+OO 6. 32E-06 2. 76E-03 

4.00E+02 6. 57E-04 7.6BE-05 O.OOE+OO B.65E-07 7.34E-04 

5.00E+02 1.B7E-04 I.13E-05 O.OOE+OO I.IBE-07 I.9BE-04 

6.00E+02 5.22E-05 I.66E-06 O.OOE+OO 1. 62E-OB 5.39E-05 

7.00E+02 1. 45E-05 2. 43E-07 O.OOE+OO O.OOE+OO I.47E-05 

B.OOE+02 3.9BE-06 3.54E .... OB O.OOE+OO O.OOE+OO 4.02E-06 

9.00E+02 I.09E-06 O.OOE+OO O.OOE+OO O.OOE+OO 1.09E-06 

I.OOE+03 3.00E-07 O.OOE+OO O.OOE+PO O.OOE+OO 3.00E-07 ... . . '. ',' 

B-303 
B-304 
CLASS W .AHAD = 1 MICRON HALFLIFE- 1.83£+13 DAYS lUIEHIOM 187 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 8. S9E-02 2.76E-Ol 2.3SE-Ol 3. 96E-02 6. 36E-Ol 

2.00E-Ol 1.20E-Ol 2.6SE-Ol 1. 97E-Ol 4. 96E-02 6. 32E-Ol 

3.00E-Ol I.SIE-Ol 2. S6E-Ol 1.66E-Ol S.37E-02 6.27E-Ol 

4.00E-Ol 1.76E-Ol 2. 47E-Ol 1. 39E-Ol S.64E-02 6.20E-Ol 

S.OOE-Ol 1.96E-Ol 2.40E-Ol 1. 17E-Ol S.84E-02 6. lIE-OI 

6.00E-Ol 2.llE-OI 2. 33E-Ol 9.86E-02 S.96E-02 6.02E-Ol 

7.00E-Ol 2. 23E-Ol 2.27E-0l 8. 29E-02 6.02E-02 S.92E-Ol 

8.00E-Ol 2. 31E-Ol 2.21E-Ol 6. 97E-02 6.02E-02 S.82E-Ol 

9.00E-0l 2. 37E-Ol 2. 16E-Ol S.86E-02 S.98E-02 5.71E-0l 

1.00E+OO 2.40E-Ol 2.llE-OI 4. 93E-02 S.89E-02 S.59E-Ol 

2.00E+OO 2.20E-Ol 1. 77E-Ol 8.72E-03 3. 95E-02 4.4SE-Ol 

3.00E+OO 1. 74E-Ol 1.60E-Ol I.S4E-03 2. 12E-02 3.S7E-Ol 

4.00E+OO 1.3SE-Ol 1. SOE-Ol 2. 72E-04 1.06E-02 2. 96E-Ol 

5.00E+OO 1.04E-Ol 1.4SE-Ol 4. 82E-OS S.30E-03 2.S4E-Ol 

6.00E+OO 8. 23E-02 1.41E-Ol 8.S1E-06 2.77E-03 2. 26E-Ol 

7.00E+OO 6.61E-02 1.38E-Ol I.S1E-06 I.S7E-03 2.06E-Ol 

8.00E+OO S.43E-02 1. 36E-Ol 2. 66E-07 1.00E-03 1.91E-0l 

9.00E+OO 4.S6E-02 1. 34E-Ol 4.70E-08 7. 29E-04 1.80E-Ol 

1.00E+Ol 3.91E-02 1.32E-Ol O.OOE+OO S.93E-04 1.72E-Ol 

2.00E+Ol 1. 74E-02 1. 16E-Ol O.OOE+OO 4.09E-04 1.34E-0l 

3.00E+Ol 1.2SE-02 1.02E-Ol O.OOE+OO 3. S6E-04 1.ISE-Ol 

4.00E+Ol 9.8SE-03 9.01E-02 O.OOE+OO 3.lOE-04 1.00E-Ol 

S.OOE+Ol 7.97E-03 7.93E-02 O.OOE+OO 2.70E-04 8.7SE-02 

6.00E+Ol 6.S3E-03 6. 98E-02 O.OOE+OO 2.3SE-04 7.6SE-02 

7.00E+Ol S.40E-03 6. 14E-02 O.OOE+OO 2.04E-04 6.70E-02 

8.00E+Ol 4. 49E-03 5.40E-02 O.OOE+OO 1. 78E-04 S.87E-02 

9.00E+Ol 3. 77E-03 4.7SE-02 O.OOE+OO 1. SSE-04 S.14E-02 

1.00E+02 3. 19E-03 4. 18E-02 O.OOE+OO 1.3SE-04 4.S1E-02 

2.00E+02 7. 39E-04 1.1SE-02 O.OOE+OO 3. 37E-OS 1. 23E-02 

3.00E+02 2.00E-04 3.1SE-03 O.OOE+OO 8. 43E-06 3. 36E-03 

4.00E+02 S.48E-OS 8. S5E-04 O.OOE+OO 2.l1E-06 9. 12E-04 

S.OOE+02 I.S0E-OS 2. 31E-04 O.OOE+OO S.27E-07 2. 46E-04 

6.00E+02 4.08E-06 6. 19E-OS O.OOE+OO 1.32E-07 6. 61E-OS 

7.00E+02 l.lOE-06 1.6SE-OS O.OOE+OO 3. 29E-08 1.77E-05 

8.00E+02 2.95E-07 4.40E-06 O.OOE+OO O.OOE+OO 4. 69E-06 

9.00E+02 7.90E-08 1. 16E-06 O.OOE+OO O.OOE+OO 1. 24E-06 , .' - ••• 1, 1.00E+03 2.10E-08 3.08E-07 O.OOE+OO O.OOE+OO 3. 29E-07 

B-30S 
CLASS W AMAD = 1 MICRON BALFLIFE= 1.83E+13 DAYS RHENIUM 187 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 63E-03 S.74E-06 

2.00E-Ol 6. 73E-03 9.01E-05 

3.00E-Ol 1.21E-02 3. 78E-04 

4.00E-Ol 1.86E-02 9. 61E-04 

S.OOE-Ol 2.S9E-02 1. B8E-03 

6.00E-Ol 3.3BE-02 3.1SE-03 

7.00E-Ol 4. 22E-02 4.7SE-03 

B.OOE-Ol S.09E-02 6.6SE-03 

9.00E-Ol S.9BE-02 B.B2E-03 

l.OOE+OO 6.BBE-02 6.8BE-02 l.l2E-02 l.l2E-02 

2.00E+OO B.SBE-02 I.SSE-Ol 2. BOE-02 3.92E-02 

3.00E+OO 6.71E-02 2. 22E-01 2.l6E-02 6.0BE-02 

4.00E+OO 4.B9E-02 2.71E-0l 1. 22E-02 7.30E-02 

S.OOE+OO 3.SlE-02 3.06E-Ol 6.19E-03 7.91E-02 

6.00E+OO 2. 54E-02 3.3lE-Ol 3.lOE-03 B.22E-02 

7.00E+OO 1.BSE-02 3.S0E-Ol 1.60E-03 B.3BE-02 

8.00E+OO 1. 37E-02 3. 63E-01 B.9SE-04 B.47E-02 

9.00E+OO 1.04E-02 3. 74E-01 S.S9E-04 B.S3E-02 

1.OOE+Ol 8.03E-03 3.82E-01 3.97E-04 8. S7E-02 

2.00E+Ol 2.11E-03 4.17E-Ol 2. 17E-04 B.BIE-02 

3.00E+Ol 1.47E-03 4. 34E-Ol 1.B9E-04 9.02E-02 

4.00E+01 1. 22E-03 4.47E-Ol 1. 64E-04 9.19E-02 

S.OOE+01 1.0SE-03 4.SBE-Ol 1. 43E-04 9.34E-02 

6.00E+Ol 9.0SE-04 4.6BE-Ol 1. 24E-04 9.4BE-02 

7.00E+01 7.B7E-04 4.76E-Ol 1.OBE-04 9.S9E-02 

B.OOE+Ol 6.B6E-04 4.B4E-01 9.43E-05 9. 69E-02 

9.00E+Ol S.99E-04 4.90E-Ol B.21E-OS 9. 78E-02 

1.00E+02 5. 23E-04 4.9SE-Ol 7.14E-OS 9. BSE-02 

2.00E+02 1.43E-04 S.24E-Ol 1.79E-OS 1.02E-Ol 

3.00E+02 3.9SE-OS S.32E-01 4. 46E-06 1.03E-01 

4.00E+02 1.09E-OS S.3SE-Ol 1.12E-06 1.04E-Ol 

S.OOE+02 2. 97E-06 S.3SE-Ol 2. 79E-07 1.04E-01 

6.00E+02 8.07E-07 S.3SE-Ol 6.98E-08 1.04E-01 

7.00E+02 2.1BE-07 S.3SE-Ol 1. 74E-OB 1.04E-Ol 

8.00E+02 S. B4E-OB S.3SE-01 O.OOE+OO 1.04E-01 

9.00E+02 1.S6E-OB S.3SE-01 O.OOE+OO 1.04E-Ol 

B-306 
CLASS W AMAD = 1 MICRON HALFLIFK= 3.78E+OO DAYS RHENIUM 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol S.44E-02 2.7lE-Ol 2.30E-OI 3.S9E-02 6.2SE-Ol 

2.00E-OI 1.16E-Ol 2. S6E-OI I.90E-Ol 4.7SE-02 6.lOE-Ol 

3.00E-Ol 1.43E-Ol 2.42E-Ol I.S7E-OI S.OSE-02 5. 93E-Ol 

4.00E-OI I.64E-OI 2.30E-Ol I.30E-OI 5..2SE-02 S.76E-OI 

S.OOE-Ol 1. 79E-Ol 2.l9E-OI I.07E-OI S.33E-02 S.5SE-Ol 

6.00E-Ol 1.S9E-Ol 2.09E-Ol S.S4E-02 5. 34E-02 5. 39E-Ol 

7.00E-Ol 1.96E-OI 1. 99E-OI 7. 29E-02 5. 29E-02 S.2lE-Ol 

S.OOE-OI I.99E-Ol I.9lE-OI 6.02E-02 5.20E-02 S.02E-Ol 

9.00E-OI 2.0lE-Ol I.S3E-Ol 4. 97E-02 5.07E-02 4.S4E-Ol 

1.OOE+OO 2.00E-Ol 1.7SE-OI 4.l1E-02 4.90E-02 4.6SE-OI 

2.00E+OO l.52E-OI 1. 23E-Ol 6.04E-03 2. 73E-02 3 .. 09E-OI 

3.00E+OO I.OOE-OI 9. 22E-02 S.S9E-04 1. 22E-02 2.06E-Ol 

4.00E+OO 6.46E-02 7. 22E-02 I.3IE-04 5.09E-03 I.42E-OI 

5.00E+OO 4.17E-02 5.7SE-02 1. 93E-05 2.12E-03 I.02E-OI 

6.00E+OO 2. 74E-02 4. 69E-02 2.S3E-06 9.22E-04 7.S2E-02 

7.00E+OO 1.S3E-02 3.S3E-02 4.17E-07 4. 36E-04 S.70E-02 

S.OOE+OO 1. 25E-02 3.l3E-02 6.l4E-OS 2.31E-04 4.41E-02 

9.00E+OO S.7SE-03 2.S7E-02 O.OOE+OO I.40E-04 3.46E-02 

1.OOE+Ol 6. 25E-03 2.11E-02 O.OOE+OO 9.47E-OS 2.7SE-02 

2.00E+Ol 4.4SE-04 2. 97E-03 O.OOE+OO I.04E-OS 3. 42E-03 

3.00E+OI S.lOE-OS 4.lSE-04 O.OOE+OO 1.4SE-06 4.70E-04 

4.00E+Ol 6.42E-06 S.SSE-OS O.OOE+OO 2.02E-07 6. S4E-OS 

5.00E+Ol S.3lE-07 S.26E-06 O.OOE+OO 2. SlE-OS 9.12E-06 

6.00E+OI I.09E-07 1.16E-06 O.OOE+OO O.OOE+OO 1. 27E-06 

7.00E+Ol I.44E-OS I.63E-07 O.OOE+OO O.OOE+OO 1.7SE-07 

B-307 
CLASS W AMAD - 1 KICRON BALFLIFE- 3.788+00 DAYS lWENIUK 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCm1ULATED 24-HOUR ACCill1ULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 58E-03 5. 63E-06 

2.00E-01 6.49E-03 8. 69E-05 

3.00E-01 1. 15E-02 3.58E-04 

4.00E-01 1. 73E-02 8. 93E-04 

5.00E-01 2. 36E-02 1.72E-03 

6.00E-01 3.03E-02 2. 82E-03 

7.00E-01 3. 71E-02 4. 18E-03 

8.00E-01 4. 39E-02 5. 75E-03 

9.00E-01 5.07E-02 7. 48E-03 

1.00E+00 5. 72E-02 5. 72E-02 9. 34E-03 9. 34E-03 

2.00E+00 5. 94E-02 1.07E-01 1.94E-02 2.72E-02 

3.00E+00 3. 87E-02 1. 28E-01 1. 25E-02 3. 51E-02 

4.00E+00 2. 35E-02 1.30E-Ol 5. 84E-03 3.50E-02 

5.00E+OO 1.40E-02 1.22E-Ol 2. 47E-03 3. 16E-02 

6.00E+00 8. 44E-03 1.10E-Ol 1.03E-03 2. 74E-02 

7.00E+00 5. 12E-03 9. 68E-02 4. 44E-04 2. 32E-02 

8.00E+00 3. 16E-03 8. 38E-02 2.06E-04 1. 95E-02 

9.00E+00 1. 99E-03 7.17E-02 1.07E-04 1. 64E-02 

1.00E+Ol 1. 28E-03 6.10E-02 6.35E-05 . 1. 37E-02 

2.00E+Ol 5.40E-05 1.06E-02 5. 53E-06 2. 25E-03 

3.00E+Ol 6.00E-06 1.77E-03 7.69E-07 3.68E-04 

4.00E+Ol 7. 94E-07 2. 92E-04 1.07E-07 6.00E-05 

5.00E+Ol 1.09E-07 4. 78E-05 1.49E-08 9.74E-06 

6.00E+Ol 1. 51E-08 7.80E-06 O.OOE+OO 1.58E-06 

'., ," , 

B-308 
CLASS W AHA» == 1 MICRON BALFLIFE= 1.40E+01 DAYS IRIDIUM 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 79E-02 2.76E-Ol 2. 34E-Ol 5.70E-02 6. 35E-Ol 

2.00E-Ol 6.S4E-02 2. 65E-OI 1. 97E-Ol 1.OSE-Ol 6. 32E-Ol 

3.00E-Ol 6. 35E-02 2.5SE-OI 1.6SE-Ol 1. 44E-Ol 6. 28E-Ol 

4.00E-Ol 6. 22E-02 2. 46E-OI 1. 39E-Ol 1. 77E-OI 6. 25E-Ol 

5.00E-OI 6.12E-02 2. 39E-OI 1. 17E-Ol 2.03E-OI 6.20E-OI 

6.00E-OI 6.05E-02 2.3IE-OI 9.8IE-02 2. 24E-OI 6.14E-OI 

7.00E-OI 5. 99E-02 2.2SE-0l 8.24E-02 2. 39E-OI 6.07E-OI 

8.00E-OI S.95E-02 2.l9E-OI 6. 92E-02 2.50E-OI 5. 98E-OI 

9.00E-OI 5.9IE-02 2.l4E-Ol 5. 82E-02 2.57E-OI S.88E-0l 

I.OOE+OO 5. 89E-02 2.09E-OI 4. 89E-02 2.6IE-OI 5. 77E-OI 

2.00E+OO 5.7SE-02 I.74E-Ol 8. 56E-03 1. 98E-Ol 4. 38E-Ol 

3.00E+OO S.65E-02 1.S5E-OI I.50E-03 I.09E-OI 3. 22E-OI 

4.00E+OO 5.S5E-02 1.4SE-Ol 2.62E-04 5. 45E-02 2. 55E-Ol 

5.00E+OO S.45E-02 1.38E-Ol 4.60E-05 2. 69E-02 2.19E-Ol 

6.00E+OO 5.36E-02 1. 33E-Ol 8.0SE-06 1. 37E-02 2.00E-OI 

7.00E+O()' 5. 27E-02 1. 29E-Ol 1.4IE-06 7.S4E-03 I.90E-Ol 

8.00E+OO S.19E-02 I.26E-OI 2. 47E-07 4. 63E-03 1.83E-0l 

9.00E+OO 5. llE-02 1. 23E-Ol 4. 32E-08 3. 23E-03 1.77E-Ol 

I.OOE+OI 5.04E-02 I.20E-OI O.OOE+OO 2. 54E-03 1. 73E-OI 

2.00E+OI 4. 46E-02 9. 64E-02 O.OOE+OO 1. 54E-03 1.42E-Ol 

3.00E+OI 4.04E-02 7. 73E-02 O.OOE+OO 1. 22E-03 I.I9E-OI 

4.00E+OI 3. 68E-02 6.l9E-02 O.OOE+OO 9. 66E-04 9. 97E-02 

5.00E+OI 3. 36E-02 4. 96E-02 O.OOE+OO 7.66E-04 8.40E-02 

6.00E+OI 3.06E-02 3. 98E-02 O.OOE+OO 6.07E-04 7. IOE-02 

7.00E+OI 2. 78E-02 3.19E-02 O.OOE+OO 4.8lE-04 6.0IE-02 

8.00E+OI 2.SIE-02 2.SSE-02 O.OOE+OO 3.8IE-04 5.IIE-02 

9.00E+OI 2. 27E-02 2.0SE-02 O.OOE+OO 3.02E-04 4.3SE-02 

I.OOE+02 2.05E-02 1. 64E-02 O.OOE+OO 2.40E-04 3.7lE-02 

2.00E+02 6. S9E-03 I.77E-03 O.OOE+OO 2.3SE-OS 8.39E-03 

3.00E+02 1. 94E-03 I.90E-04 O.OOE+OO 2.30E-06 2.l3E-03 

4.00E+02 5.S2E-04 2.02E-05 O.OOE+OO 2.26E-07 S.72E-04 

S.OOE+02 I.SSE-04 2.14E-06 O.OOE+OO 2.2lE-08 1.57E-04 

6.00E+02 4.30E-OS 2.25E-07 O.OOE+OO O.OOE+OO 4. 32E-05 

7.00E+02 1.19E-OS 2.3SE-08 O.OOE+OO O.OOE+OO I.20E-OS 

8.00E+02 3.3IE-06 O.OOE+OO O.OOE+OO O.OOE+OO 3.3IE-06 

9.00E+02 9.l9E-07 O.OOE+OO O.OOE+OO O.OOE+OO 9.l9E-07 '., . ':. -

.; " I.OOE+03 2.5SE-07 O.OOE+OO O.OOE+OO O.OOE+OO 2.5SE-07 ,', . ' 

B-309 
CLASS II AMAD = 1 MICRON HALPLlFE= 7.40£+01 DAYS IRIDIUM 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-0l 3.09E-03 8.09E-06 

2.00E-Ol S.92E-03 1. 63E-04 

3.00E-OI S.IOE-03 8.24E-04 

4.00E-Ol 9.80E-03 2.40E-03 

S.OOE-OI I.IIE-02 S.23E-03 

6.00E-Ol 1. 22E-02 9.S2E-03 

7.00E-OI 1.30E-02 I.S3E-02 

S.OOE-OI 1. 37E-02 2. 27E-02 

9.00E-Ol 1.42E-02 3.14E-02 

I.OOE+OO 1. 47E-02 I. 47E-02 4.ISE-02 4.1SE-02 

2.00E+OO 2. 32E-03 1.69E-02 1. 32E-Ol 1. 73E-Ol 

3.00E+OO 1.2SE-03 I.80E-02 I.IOE-Ol 2.S1E-OI 

4.00E+OO 1.06E-03 I.S9E-02 6. 33E-02 3.42E-Ol 

S.OOE+OO 9.7SE-04 I. 96E-02 3. 22E-02 3. 71E-OI 

6.00E+OO 9.07E-04 2.04E-02 I.60E-02 3.S3E-Ol 

7.00E+OO S.49E-04 2.10E-02 S.13E-03 3.8SE-OI 

8.00E+OO 7. 97E-04 2.16E-02 4.44E-03 3.S9E-Ol 

9.00E+OO 7.S0E-04 2. 22E-02 2.70E-03 3.SSE-Ol 

1.OOE+0l 7.07E-04 2. 27E-02 1. S6E-03 3.86E-OI 

2.00E+Ol 4.31E-04 2.S8E-02 S.91E-04 3.62E-Ol 

3.00E+OI 3.06E-04 2. 69E-02 7.06E-04 3.37E-0l 

4.00E+OI 2.4IE-04 2.70E-02 S.60E-04 3.13E-Ol 

S.OOE+Ol 2.0IE-04 2. 67E-02 4.44E-04 2. 89E-Ol 

6.00E+OI 1.72E-04 2.6IE-02 3.S2E-04 2. 67E-Ol 

7.00E+Ol 1.49E-04 2.S3E-02 2.79E-04 2.46E-OI 

S.OOE+Ol 1.30E-04 2. 43E-02 2.2IE-04 2. 27E-OI 

9.00E+Ol I.14E-04 2. 33E-02 1.7SE-04 2.0SE-Ol 

1.OOE+02 9. 96E-OS 2. 23E-02 1. 39E-04 1.9IE-OI 

2.00E+02 2. 66E-OS 1.20E-02 I.36E-OS 7. 79E-02 

3.00E+02 7.I9E-06 S.SSE-03 1. 33E-06 3.0SE-02 

4.00E+02 1.97E-06 2.4IE-03 I.31E-07 1.21E-02 

S.OOE+02 S.42E-07 1.OlE-03 1.2SE-OS 4.7SE-03 

6.00E+02 1. SOE-07 4.14E-04 O.OOE+OO I~S6E-03 

7.00E+02 4.1SE-OS 1.67E-04 O.OOE+OO 7.30E-04 

S.OOE+02 1.lSE-08 6.70E-OS O.OOE+OO 2.86E-04 

B-310 
CLASS W AMAD == 1 KICRON STABLE IRIDIUM 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. BOE-02 2.76E-0l 2.35E-Ol 5.71E-02 6.36E-Ol 

2.00E-Ol 6. 55E-02 2. 65E-Ol 1. 97E-Ol 1.05E-Ol 6.33E-Ol 

3.00E-Ol 6.37E-02 2. 56E-Ol 1.66E-Ol 1.45E-Ol 6.30E-Ol 

4.00E-Ol 6. 24E-02 2. 47E-Dl 1. 39E-Ol 1.7BE-Ol 6.27E-Ol 

5.00E-Ol 6.l5E-02 2.40E-Ol 1.17E-Ol 2.04E-Ol 6.23E-Ol 

6.00E-Ol 6.0BE-02 2. 33E-Ol 9.B6E-02 2. 25E-Ol 6.l7E-Ol 

7.00E-Ol 6.03E-02 2.27E-Ol B.29E-02 2.4lE-0l 6.llE-Ol 

B.OOE-Ol 5. 99E-02 2.2lE-Ol 6. 97E-02 2. 52E-Ol 6.02E-Ol 

9.00E-Ol 5. 96E-02 2.l6E-Ol 5.B6E-02 2.59E-Ol 5. 93E-Ol 

1.OOE+OO 5. 94E-02 2.llE-Ol 4. 93E-02 2. 63E-Ol 5.B2E-Ol 

2.00E+OO 5.86E-02 1.77E-Ol B.72E-03 2.0lE-0l 4.46E-Ol 

3.00E+OO 5. BlE-02 1.60E-Ol 1. 54E-03 1.12E-Ol 3. 32E-Ol 

4.00E+OO 5. 76E-02 1.50E-0l 2. 72E-04 5.66E-02 2. 65E-Ol 

5.00E+OO 5.7lE-02 1.45E-Ol 4.B2E-05 2.B2E-02 2.30E-Ol 

6.00E+OO 5. 67E-02 1.41E-0l B.5lE-06 1.45E-02 2.l2E-Ol 

7.00E+OO 5. 63E-02 1.3BE-Ol 1.5IE-06 B.05E-03 2.02E-Dl 

B.OOE+OO 5.60E-02 1.36E-Ol 2. 66E-07 4. 99E-03 1.97E-0l 

9.00E+OO 5. 56E-02 1. 34E-Ol 4.70E-OB 3.5lE-03 1. 93E-Ol 

1.OOE+Ol 5. 53E-02 1.32E-0l O.OOE+OO 2.79E-03 1.90E-Ol 

2.00E+Ol 5.3BE-02 1.16E-Ol O.OOE+OO 1.B5E-03 1. 72E-Ol 

3.00E+Ol 5. 35E-02 1.02E-Ol O.OOE+OO 1.6lE-03 1. 57E-Ol 

4.00E+Ol 5. 35E-02 9.0lE-02 O.OOE+OO 1.40E-03 1.45E-Ol 

5.00E+Ol 5. 36E-02 7. 93E-02 O.OOE+OO 1.22E-03 1. 34E-Ol 

6.00E+Ol 5. 36E-02 6.9BE-02 O.OOE+OO 1.06E-03 1. 24E-Ol 

7.00E+Ol 5. 35E-02 6.l4E-02 O.OOE+OO 9.27E-04 1.16E-Ol 

B.OOE+Ol 5. 32E-02 S.40E-02 O.OOE+OO B.07E-04 1.OBE-Ol 

9.00E+Ol S.2BE-02 4.7SE-02 O.OOE+OO 7.02E-04 1.OlE-0l 

1.OOE+02 S.22E-02 4.lBE-02 O.OOE+OO 6.l2E-04 9.46E-02 

2.00E+02 4. 29E-02 1.lSE-02 O.OOE+OO 1. S3E-04 S.46E-02 

3.00E+02 3. 22E-02 3.lSE-03 O.OOE+OO 3.B2E-OS 3. 54E-02 

4.00E+02 2. 34E-02 B. SSE-04 O.OOE+OO 9.56E-06 2.42E-02 

5.00E+02 1. 67E-02 2.3lE-04 O.OOE+OO 2. 39E-06 1. 69E-02 

6.00E+02 1.19E-02 6.l9E-05 O.OOE+OO S.97E-07 1.19E-02 

7.00E+02 B.40E-03 1. 65E-OS O.OOE+OO 1. 49E-07 B.4lE-03 

B.OOE+02 S.94E-03 4.40E-06 O.OOE+OO 3. 73E-OB S.9SE-03 

9.00E+02 4.20E-03 1.16E-06 O.OOE+OO O.OOE+OO 4.20E-03 

1.OOE+03 2. 97E-03 3.0BE-07 O.OOE+OO O.OOE+OO 2. 97E-03 

2.00E+03 9.30E-OS O.OOE+OO O.OOE+OO O.OOE+OO 9.30E-OS 

3.00E+03 2.9lE-06 O.OOE+OO O.OOE+OO O.OOE+OO 2.9lE-06 

4.00E+03 9.09E-OB O.OOE+OO O.OOE+OO O.OOE+OO 9.09E-OB 

B-3ll 
CLASS W AMAD = 1 MICRON STABLE IRIDIUM 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------.---------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 3.09E-03 8.09E-06 

2.00E-01 5. 93E-03 1. 64E-04 

3.00E-01 8. 12E-03 8.27E-04 

4.00E-01 9. 84E-03 2.41E-03 

5.00E-01 1.12E-02 5.26E-03 

6.00E-01 1.22E-02 9.57E-03 

7.00E-01 1.31E-02 1.54E-02 

8.00E-01 1. 38E-02 2.29E-02 

9.00E-01 1. 44E-02 3. 17E-02 

1.00E+00 1.48E-02 1. 48E-02 4. 19E-02 4. 19E-02 

2.00E+00 2.36E-03 1.72E-02 1.34E-01 1.76E-01 

3.00E+00 1. 28E-03 1. 85E-02 1. 13E-01 2.89E-01 

4.00E+00 1.10E-03 1.96E-02 6. 57E-02 3.55E-01 

5.00E+00 1.02E-03 2.06E-02 3. 38E-02 3. 89E-01 

6.00E+00 9.60E-04 2. 16E-02 1. 69E-02 4.06E-01 

7.00E+00 9.07E-04 2. 25E-02 8. 68E-03 4. 14E-01 

8.00E+00 8. 59E-04 2. 33E-02 4.78E-03 4.19E-01 

9.00E+00 8. 15E-04 2.41E-02 2. 93E-03 4.22E-01 

1.00E+01 7.76E-04 2. 49E-02 2.05E-03 4.24E-01 

2.00E+01 5.20E-04 3.11E-02 1.07E-03 4.36E-01 

3.00E+01 4.06E-04 3. 56E-02 9.35E-04 4.46E-01 

4.00E+01 3.51E-04 3. 93E-02 8. 14E-04 4. 55E-01 

5.00E+01 3. 21E-04 4. 26E-02 7.08E-04 4.62E-01 

6.00E+01 3.02E-04 4.57E-02 6. 17E-04 4.69E-01 

7.00E+01 2.87E-04 4. 87E-02 5.37E-04 4.75E-01 

8.00E+01 2. 75E-04 5. 15E-02 4. 67E-04 4.80E-01 

9.00E+01 2. 64E-04 5.42E-02 4.07E-04 4.84E-01 

1.00E+02 2. 54E-04 5. 68E-02 3. 54E-04 4. 88E-01 

2.00E+02 1. 73E-04 7. 78E-02 8.86E-05 5.07E-01 

3.00E+02 1. 19E-04 9.22E-02 2.21E-05 5. 12E-01 

4.00E+02 8. 33E-05 1.02E-01 5.53E-06· 5. 13E-01 

5.00E+02 5.86E-05 1.09E-01 1. 38E-06 5. 13E-01 

6.00E+02 4. 13E-05 1. 14E-01 3.46E-07 5.13E-01 

7.00E+02 2. 92E-05 1. 18E-01 8. 65E-08 5. 13E-01 .. , 8.00E+02 2.06E-05 1.20E-01 2.16E-08 5. 13E-01 

9.00E+02 1.46E-05 1.22E-01 O.OOE+OO 5.13E-01 

1.00E+03 1.03E-05 1.23E-01 O.OOE+OO 5.13E-01 

2.00E+03 3. 23E-07 1.26E-01 O.OOE+OO 5. 13E-01 

3.00E+03 1.01E-08 1.26E-01 O.OOE+OO 5. 13E-01 

B-312 
CLASS W AKAD = 1 KICRON STABLE GOLD 197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 7.04E-02 2. 76E-01 2. 35E-01 5. 64E-02 6. 38E-01 

2.00E-01 7. 16E-02 2. 65E-01 1. 97E-01 1.02E-01 6. 36E-01 

3.00E-01 7. 36E-02 2.56E-01 1.66E-Ol 1.38E-01 6. 34E-01 

4.00E-01 7.58E-02 2. 47E-01 1. 39E-01 1. 68E-Ol 6.30E-01 

5.00E-01 7. 77E-02 2.40E-01 1. 17E-01 1.91E-01 6. 26E-01 

6.00E-01 7.92E-02 2. 33E-01 9.86E-02 2.09E-01 6.20E-01 

7.00E-01 8.03E-02 2. 27E-01 8. 29E-02 2.23E-01 6. 13E-Ol 

8.00E-01 8. 11E-02 2. 21E-01 6. 97E-02 2. 32E-01 6.04E-01 

9.00E-01 8. 14E-02 2. 16E-01 5. 86E-02 2. 38E-01 5. 94E-01 

1.00E+00 8. 15E-02 2. 11E-01 4. 93E-02 2. 41E-01 5. 82E-Ol 

2.00E+00 7. 36E-02 1. 77E-01 8.72E-03 1. 82E-01 4.42E-01 

3.00E+00 6. 15E-02 1.60E-01 1. 54E-03 1.01E-01 3. 24E-01 

4.00E+00 5.03E-02 1.50E-01 2.72E-04 5.09E-02 2. 52E-01 

5.00E+00 4.09E-02 1.45E-01 4. 82E-05 2. 53E-02 2. llE-Ol 

6.00E+00 3. 32E-02 1.41E-01 8. 51E-06 1.31E-02 1. 87E-01 

7.00E+00 2.70E-02 1.38E-Ol 1.51E-06 7. 26E-03 1. 72E-Ol 

8.00E+00 2.21E-02 1.36E-Ol 2.66E-07 4.51E-03 1. 62E-01 

9.00E+00 1.81E-02 1.34E-Ol 4.70E-08 3. 18E-03 1. 55E-Ol 

1.00E+01 1.49E-02 1.32E-01 O.OOE+OO 2. 53E-03 1.50E-Ol 

2.00E+Ol 3. 64E-03 1. 16E-01 O.OOE+OO 1. 69E-03 1. 22E-01 

3.00E+Ol 2.30E-03 1.02E-01 O.OOE+OO 1. 47E-03 1.06E-Ol 

4.00E+01 1. 97E-03 9.01E-02 O.OOE+OO 1. 28E-03 9. 33E-02 

5.00E+01 1. 76E-03 7. 93E-02 O.OOE+OO 1. llE-03 8.21E-02 

6.00E+01 1. 58E-03 6. 98E-02 O.OOE+OO 9.70E-04 7.23E-02 

7.00E+01 1. 42E-03 6. 14E-02 O.OOE+OO 8.44E-04 6. 36E-02 

3.00E+01 1. 27E-03 5.40E-02 O.OOE+OO 7. 35E-04 5.60E-02 

9.00E+01 1. 14E-03 4. 75E-02 O.OOE+oo 6.40E-04 4. 93E-02 

1.00E+02 1.02E-03 4. 18E-02 O.OOE+OO 5. 57E-04 4. 34E-02 

2.00E+02 3.24E-04 1. 15E-02 O.OOE+OO 1.39E-04 1.20E-02 

3.00E+02 9. 82E-05 3. 15E-03 O.OOE+OO 3. 48E-05 3. 28E-03 

4.00E+02 2.89E-05 8. 55E-04 O.OOE+OO 8. 71E-06 8. 93E-04 

5.00E+02 8. 29E,06 2.31E-04 O.OOE+OO 2. 18E-06 2.41E-04 

6.00E+02 2. 34E-06 6. 19E-05 O.OOE+OO 5. 44E-07 6. 48E-05 

7.00E+02 6. 53E-07 1. 65E-05 O.OOE+OO 1. 36E-07 1. 73E-05 

8.00E+02 1.80E-07 4.40E-06 O.OOE+OO 3.40E-08 4. 61E-06 

9.00E+02 4. 92E-08 1. 16E-06 O.OOE+OO O.OOE+OO 1. 21E-06 .! . 1.00E+03 1.34E-08 3.08E-07 O.OOE+OO O.OOE+OO 3. 21E-07 

B-313 
CLASS W AMAD= 1 MICRON STABLE GOLD 197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE.;.Ol 1.40E-03 8.01E-06 

2.00E-Ol 3.03E-03 1.60E-04 

3.00E-Ol 4.71E-03 8.04E-04 

4.00E-Ol 6.44E-03 2. 33E-03 

S.OOE-Ol 8.2lE-03 S.04E-03 

6.00E-Ol 1.OOE-02 9.13E-03 

7.00E-Ol 1.19E-02 1.47E-02 

8.00E-Ol 1.37E-02 2.l6E-02 

9.OOE-Ol 1.S6E-02 2. 98E-02 

1.OOE+OO 1.7SE-02 1.7SE-02 3. 93E-02 3. 93E-02 

2.00E+OO 1.8lE-02 3.S6E-02 1.23E-Ol 1.62E-Ol 

3.00E+OO 1. 56E-02 S.12E-02 1.02E-Ol 2.64E-OI 

4.00E+OO I.29E-02 6.4lE-02 S.92E-02 3.23E-Ol 

S.OOE+OO 1.0SE-02 7.46E-02 3.04E-02 3.S4E-OI 

6.00E+OO 8.S4E-03 8. 32E-02 1.S2E-02 3. 69E-Ol 

7.00E+OO 6. 94E-03 9.0lE-02 7.8lE-03 3. 77E-OI 

8.00E+OO S.65E-03 9.S7E-02 4.31E-03 3.81E-0l 

9.00E+OO 4. 62E-03 1.OOE-Ol 2.6SE-03 3. 84E-Ol 

1.OOE+Ol 3.79E-03 1.04E-Ol 1.8SE-03 3.8SE-Ol 

2.00E+Ol 8. 78E-04 1.2IE-Ol 9.77E-04 3. 97E-Ol 

3.00E+OI 5. 38E-04 1.27E-Ol 8.S0E-04 4.06E-OI 

4.00E+OI 4.S9E-04 1.32E-Ol 7.40E-04 4.13E-Ol 

S.OOE+Ol 4.10E-04 1.37E-Ol 6. 44E-04 4.20E-Ol 

6.00E+Ol 3.6SE-04 1.4lE-OI S.6lE-04 4.26E-Ol 

7.00E+Ol 3.30E-04 1.44E-Ol 4.88E-04 4.32E-Ol 

8.00E+Ol 2. 96E-04 1. 47E-Ol 4.2SE-04 4. 36E-Ol 

9.00E+Ol 2.6SE-04 1.SOE-Ol 3.70E-04 4.40E-Ol 

1.OOE+02 2. 37E-04 1.S2E-OI 3. 22E-04 4.43E-Ol 

2.00E+02 7.S2E-OS 1.66E-Ol S.OSE-OS 4.6lE-Ol 

3.00E+02 2.2SE-OS 1.71E-Ol 2.0lE-OS 4.6SE-Ol 

4.00E+02 6.7lE-06 1.72E-Ol S.03E-06 4.66E-Ol 

S.OOE+02 1. 93E-06 1. 73E-Ol 1. 26E-06 4.66E-Ol 

6.00E+02 S.44E-07 1.73E-Ol 3.l4E-07 4.66E-Ol 

7.00E+02 I.S2E-07 1. 73E-Ol 7.B6E-08 4.66E-Ol 

B.OOE+02 4.lBE-OS 1.73E-Ol 1.97E-08 4.66E-Ol 

9.00E+02 1. 14E-OS 1.73E-Ol O.OOE+OO 4. 66E-Ol 

B-314 
CLASS W AMAD = 1 KICRON STABLE BISHtTl'H 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 38E-02 2.76E-OI 2.3SE-Ol S.68E-02 6. 32E-OI 

2.00E-Ol S.78E-02 2.6SE-Ol 1. 97E-OI 1.04E-Ol 6. 24E-OI 

3.00E-Ol S.34E-02 2. S6E-OI 1. 66E-OI 1.42E-Ol 6.17E-Ol 

4.00E-Ol 4. 99E-02 2. 47E-Ol 1. 39E-OI 1. 73E-Ol 6.lOE-OI 

S.OOE-Ol 4.70E-02 2.40E-Ol I.I7E-OI I.99E-Ol 6.03E-Ol 

6.00E-Ol 4.4SE-02 2. 33E-Ol 9. 86E-02 2.18E-Ol S.94E-Ol 

7. QOE-OI 4. 23E-02 2.27E-OI 8.29E-02 2. 33E-Ol S.8SE-OI 

8.00E-Ol 4.03E-02 2.2IE-Ol 6. 97E-02 2. 43E-Ol S.74E-Ol 

9.00E-Ol 3.8SE-02 2.16E-0l S.86E-02 2. SOE-OI S.63E-OI 

I.OOE+OO 3. 68E-02 2.llE-Ol 4. 93E-02 2.S3E-Ol S.SOE-OI 

2.00E+OO ' 2. S6E-02 1.77E-Ol 8. 72E-03 I.93E-Ol 4.04E-Ol 

3.00E+OO 2.00E-02 1.60E-Ol 1. S4E-03 I.07E-Ol 2.89E-Ol 

4.00E+OO 1. 67E-02 1. SOE-Ol 2. 72E-04 S.40E-02 2.2IE-Ol 

S.OOE+OO I.44E-02 1.4SE-Ol 4. 82E-OS 2. 69E-02 1. 86E-Ol 

6.00E+OO 1. 26E-02 1.4IE-0l 8.S1E-06 1.39E-02 1.67E-OI 

7.00E+OO 1.1IE-02 1. 38E-Ol I.SIE-06 7.70E-03 1. S7E-Ol 

8.00E+OO 9. 86E-03 1.36E-OI 2. 66E-07 4.77E-03 I.SIE-OI 

9.00E+OO 8.7SE-03 1. 34E-O 1 4.70E-08 3. 36E-03 1. 46E-Ol 

1.OOE+OI 7. 78E-03 1.32E-Ol O.OOE+OO 2. 67E-03 1.43E-Ol 

2.00E+Ol 2. 87E-03 1.16E-Ol O.OOE+OO 1. 78E-03 1.2IE-Ol 

3.00E+Ol 1.SSE-03 1.02E-Ol O.OOE+OO 1. SSE-03 1.OSE-Ol 

4.00E+OI 1.I4E-03 9.0IE-02 O.OOE+OO 1.3SE-03 9.2SE-02 

S.OOE+Ol 9.6SE-04 7.93E-02 O.OOE+OO I.17E-03 8.14E-02 

6.00E+Ol 8.S3E-04 6. 98E-02 O.OOE+OO 1.02E-03 7.16E-02 

7.00E+OI 7. 64E-04 6.14E-02 O.OOE+OO 8.90E-04 6.30E-02 

8.00E+Ol 6.8SE-04 S.40E-02 O.OOE+OO 7.7SE-04 S.SSE-02 

9.00E+Ol 6. ISE-04 4.7SE-02 O.OOE+OO 6.7SE-04 4. 88E-02 

I.OOE+02 S.S2E-04 4.18E-02 O.OOE+OO S.87E-04 4. 29E-02 

2.00E+02 1. 79E-04 1. ISE-02 O.OOE+OO 1.47E-04 1.I9E-02 

3.00E+02 S.48E-OS 3. ISE-03 O.OOE+OO 3. 67E-OS 3. 24E-03 

4.00E+02 1. 63E-OS 8. SSE-04 O.OOE+OO 9.18E-06 8.81E-04 

S.OOE+02 4.70E-06 2.3IE-04 O.OOE+OO 2.29E-06 2. 38E-04 

6.00E+02 1. 33E-06 6.19E-OS O.OOE+OO S.74E-07 6.38E-OS 

7.00E+02 3. 73E-07 1.6SE-OS O • .oOE+OO I.43E-07 I.70E-OS 

8.00E+02 I.03E-07 4.40E-06 O.OOE+OO 3.S8E-08 4.S3E-06 

9.00E+02 2. 83E-08 I.I6E-06 O.OOE+OO O.OOE+OO I.I9E-06 

. , 

B-3IS 
CLASS W AHA» = 1 MICRON STABLE BISMUTH 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------.----------------------

SYSTEMIC NON-SYSTEMIC 

-----------~------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 7. 54E-03 8.06E-06 

2.00E-Ol 1.50E-02 1. 62E-04 

3.00E-Ol 2.l2E-02 8.l7E-04 

4.00E-Ol 2. 67E-02 2. 38E-03 

5.00E-Ol 3.l4E-02 5.l6E-03 

6.00E-Ol 3. 56E-02 9. 38E-03 

7.00E-Ol 3.93E-02 1.5lE-02 

8.00E-Ol 4. 27E-02 2. 23E-02 

9.00E-Ol 4.57E-02 3.09E-02 

1.OOE+OO 4. 83E-D2 4. 83E-02 4.07E-02 4.07E-02 

2.00E+OO 1. 66E-02 6.50E-02 1.29E-Ol 1.70E-Ol 

3.00E+OO 7.6lE-03 7. 26E-02 1.08E-Ol 2. 78E-Ol 

4.00E+OO 4.4lE-03 7.70E-02 6.28E-02 3.4lE-Ol 

5.00E+OO 3.llE-03 8.0lE-02 3. 23E-02 3. 73E-Ol 

6.00E+OO 2. 48E-03 8. 26E-02 1.6lE-02 3.89E-Ol 

7.00E+OO 2.llE-03 8.47E-02 8. 29E-03 3. 98E-Ol 

8.00E+OO 1. 86E-03 8. 65E-02 4.57E-03 4.02E-Ol 

9.00E+OO 1. 66E-03 8. 82E-02 2.8lE-03 4.05E-Ol 

1.OOE+Ol 1.5lE-03 8.97E-02 1.96E-03 4.07E-Ol 

2.00E+Ol 7. 34E-04 9.97E-02 1.03E-03 4.l9E-Ol 

3.00E+Ol 5.08E-04 1.06E-Ol 8. 97E-04 4. 28E-Ol 

4.00E+Ol 4.20E-04 1.lOE-Ol 7.8lE-04 4. 36E-Ol 

5.00E+Ol 3.69E-04 1.14E-Ol 6.80E-04 4. 44E-Ol 

6.00E+Ol 3.30E-04 1.18E-Ol 5. 92E-04 4.50E-Ol 

7.00E+Ol 2. 96E-04 1.2lE-0l 5.l5E-04 4. 55E-Ol 

8.00E+Ol 2. 66E-04 1.23E-Ol 4. 48E-D4 4.60E-Ol 

9.00E+Ol 2. 39E-04 1.26E-Ol 3.90E-04 4. 64E-Ol 

1.OOE+02 2.l4E-04 1. 28E-Ol 3.40E-04 4. 68E-Ol 

2.00E+02 6.9lE-05 1.4lE-Ol 8.50E-05 4. 86E-Ol 

3.00E+02 2.l2E-05 1. 45E-Ol 2.l2E-05 4.9lE-Ol 

4.00E+02 6. 27E-06 1.46E-0l 5.3lE-06 4. 92E-Ol 

5.00E+02 1.8lE-06 1. 47E-0l 1. 33E-06 4. 92E-Ol 

6.00E+02 5.l4E-07 1. 47E-0l 3.32E-07 4. 92E-Ol 

7.00E+02 1. 44E-07 1. 47E-Ol 8.30E-08 4. 92E-Ol 

8.00E+02 3. 98E-08 1.47E-Ol 2.07E-08 4.92E-Ol 

9.00E+02 1.09E-08 1.47E-Ol O.OOE+OO 4. 92E-Ol 

B-3l6 
CLASS W AHAD - 1 KICRON BALFLIFE= 1.38E+02 DAYS POLONIUM 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.l7E-02 2. 76E-Ol 2.3SE-Ol S.63E-02 6.39E-Ol 

2.00E-ol 7. 44E-02 2. 65E-Ol 1. 97E-Ol 1.02E-Ol 6. 38E-Ol 

3.00E-Ol 7. 79E-02 2.S5E-Ol 1.66E-Ol 1.38E-Ol 6.37E-OI 

4.00E-Ol 8.l7E-02 2. 47E-Ol 1.39E-ol 1. 68E-Ol 6. 35E-OI 

5.00E-ol 8. 52E-02 2.39E-Ol 1.17E-0l 1.9IE-Ol 6.32E-ol 

6.00E-OI 8. 84E-02 2. 32E-OI 9. 83E-02 2.09E-Ol 6.27E-Ol 

7.0oE-Ol 9.IIE-02 2. 26E-OI 8. 27E-02 2. 22E-OI 6.22E-0l 

8.00E-Ol 9.35E-02 2.20E-Ol 6. 95E-02 2.3IE-OI 6.l4E-OI 

9.00E-OI 9.S6E-02 2.ISE-Ol S.84E-02 2.37E-OI 6.06E-Ol 

I.OOE+oO 9.74E-02 2.1OE-OI 4.9IE-02 2.40E-OI S.96E-OI 

2.00E+OO I.06E-OI 1.76E-Ol 8. 63E-03 1.80E-OI 4.7oE-ol 

3.00E+OO I.07E-Ol I. 57E-ol 1. 52E-03 9. 94E-02 3. 65E-ol 

4.00E+OO 1.07E-Ol 1. 47E-OI 2. 67E-04 4. 99E-02 3.04E-Ol 

S.OOE+Oo I.06E-OI 1.4IE-OI 4.70E-OS 2. 47E-02 2.71E-OI 

6.o0E+OO I.OSE-OI 1.37E-Ol 8. 26E-06 1.27E-02 2.S4E-OI 

7.00E+OD I.03E-D1 1. 33E-OI 1. 45E-06 7.0lE-03 2. 44E-OI 

8.00E+OO I.02E-OI 1.3IE-OI 2. 56E-07 4. 33E-03 2.37E-OI 

9.00E+OO I.OIE-Ol 1. 28E-OI 4.S0E-08 3.04E-03 2. 32E-Ol 

I.OOE+Ol 9. 94E-02 1. 26E-Ol O.OOE+OO 2.4IE-03 2.27E-Ol 

2.00E+OI 8.70E-02 1.05E-Ol O.OOE+OO 1. 53E-03 1. 94E-OI 

3.00E+OI 7.6lE-02 8.80E-02 O.OOE+OO 1. 27E-03 1.65E-OI 

4.00E+Ol 6.6SE-02 7.37E-02 O.OoE+OO I.05E-03 1.4lE-ol 

S.OOE+OI S.80E-02 6.l7E-02 O.OOE+OO 8. 67E-04 1.2IE-ol 

6.00E+OI S.06E-02 S.16E-02 O.OOE+OO 7.l8E-04 1.o3E-Ol 

7.00E+Ol 4.40E-02 4. 32E-02 O.OOE+OO S.95E-04 8.78E-02 

8.00E+OI 3. 83E-02 3. 62E-02 O.OOE+oO 4. 92E-04 7. 49E-02 

9.00E+Ol 3. 33E-02 3.03E-02 O.OOE+OO 4.08E-04 6.39E-02 

1.OOE+02 2. 89E-02 2.S3E-02 o.OOE+OO 3. 38E-04 S.4SE-02 

2.00E+02 6. 69E-03 4. 23E-03 O.OOE+OO S.llE-OS l.lOE-02 

3.00E+02 1. 44E-03 7.0lE-04 O.OOE+OO 7.7SE-06 2.ISE-03 

4.00E+02 2. 97E-04 1.ISE-04 O.OOE+OO 1.17E-06 4.l3E-04 

S.OOE+02 S.B6E-OS 1. 89E-05 O.OOE+OO 1. 78E-07 7. 76E-OS 

6.00E+02 1.12E-OS 3.06E-06 O.OOE+OO 2. 69E-oB I. 43E-OS 

7.00E+02 2.1OE-06 4. 96E-07 O.OOE+OO O.OOE+OO 2.60E-06 

8.00E+02 3.85E-07 7. 99E-OB O.OOE+OO O.OOE+OO 4. 65E-07 

9.00E+02 6. 94E-08 1. 28E-08 O.OOE+OO O.OOE+OO 8. 22E-08 

1.OOE+03 1. 23E-08 O.OOE+OO O.OOE+OO O.OOE+OO 1. 23E-08 

B-317 
CLASS W AHAD= 1 MICRON lIALFLIFE= 1. 38E+02 DAYS POLONIUM 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 8. 47E-06 8. 43E-OS 

2.00E-Ol 1. 86E-OS 3. 28E-04 

3.00E-Ol 2. 92E-OS 1.07E-03 

4.00E-OI 4.02E-OS 2. 69E-03 

S.OOE-Ol S.18E-OS S.SOE-03 

6.00E-OI 6. 39E-OS 9. 67E-03 

7.00E-Ol 7. 63E-OS I.S3E-02 

8.00E-Ol 8.9lE-OS 2. 23E-02 

9.00E-Ol 1.02E-04 3.06E-02 

I.OOE+OO 1.16E-04 I.16E-04 4.0IE-02 4.0IE-02 

2.00E+00 I.42E-04 2. S7E-04 I.23E-OI 1.63E-Ol 

3.00E+00 I. 48E-04 4.04E-04 1.02E-OI 2. 64E-OI 

4.00E+00 I. 48E-04 S.SOE-04 S.93E-02 3.22E-OI 

S.OOE+OO 1.47E-04 6. 94E-04 3.09E-02 3.SIE-01 

6.00E+00 1. 46E-04 8.37E-04 1.60E-02 3.6SE-Ol 

7.00E+00 1. 44E-04 9.77E-04 8. 84E-03 3. 72E-OI 

8.00E+OO 1. 42E-04 I.lIE-03 S.42E-03 3. 76E-OI 

9.00E+OO 1.4lE-04 I.2SE-03 3.80E-03 3.7SE-OI 

I.OOE+Ol 1. 39E-04 1. 38E-03 3.0IE-03 3. 79E-OI 

2.00E+OI 1.2IE-04 2.S8E-03 I.9SE-03 3. 82E-OI 

3.00E+OI I.06E-04 3. SSE-03 1.69E-03 3. 8lE-·01 

4.00E+Ol 9.28E-OS 4. 34E-03 I. 44E-03 3. 78E-OI 

S.OOE+Ol 8. IDE-OS 4. 97E-03 I.23E-03 3.72E-OI 

6.00E+Ol 7.06E-OS S.47E-03 1.OSE-03 3.6SE-OI 

7.00E+Ol 6.14E-OS S.84E-03 8.97E-04 3.S6E-OI 

8.00E+OI S.34E-OS 6.IlE-03 7. 66E-04 3.4.7E-Ol 

9.00E+OI 4. 64E-OS 6. 29E-03 6.S4E-04 3.37E-Ol 

I.OOE+02 4.03E-OS 6.4lE-03 S.S8E-04 3. 26E-OI 

2.00E+02 9. 34E-06 S.46E-03 I.I4E-04 2.ISE-OI 

3.00E+02 2.02E-06 3. 66E-03 2. 26E-OS 1. 36E-Ol 

4.00E+02 4.lSE-07 2.29E-03 4.4IE-06 8.3SE-02 

S.OOE+02 8.19E-08 1.40E-03 8.40E-07 S.07E-02 

6.00E+02 I.S7E-08 8.54E-04 I. S7E-07 3.08E-02 

B-3l8 
CLASS W AHA» = 1 KICRON S'l'ABI..E ASTATINE 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 1.07E-Ol 2.76E-0l 2.3SE-Ol 2.lOE-02 6. 39E-Ol 

2.00E-Ol 1.SSE-Ol 2.6SE-Ol 1.97E-Ol 1. 96E-02 6.38E-Ol 

3.00E-Ol 1.98E-0l 2.S6E-Ol 1. 66E-Ol 1. 68E-02 6. 36E-0l 

4.00E-Ol 2. 34E-Ol 2. 47E-Ol 1. 39E-Ol 1. 43E-02 6.3SE-Ol 

S.OOE-Ol 2. 64E-Ol 2.40E-Ol 1.17E-Ol 1.22E-02 6. 33E-Ol 

6.00E-Ol 2. 89E-Ol 2. 33E-Ol 9. 86E-02 1.OSE-02 6.3lE-Ol 

7.00E-Ol 3.llE-Ol 2. 27E-Ol 8. 29E-02 9.0lE-03 6.29E-Ol 

8.00E-Ol 3. 29E-Ol 2.2lE-Ol 6. 97E-02 7.77E-03 6.27E-Ol 

9.00E-Ol 3.44E-Ol 2.l6E-Ol S.86E-02 6.72E-03 6.2SE-Ol 

1.OOE+OO 3.S6E-Ol 2.llE-Ol 4. 93E-02 S.83E-03 6. 22E-Ol 

2.00E+OO 4.08E-Ol 1. 77E-Ol 8. 72E-03 1. 66E-03 S.9SE-Ol 

3.00E+OO 4.0SE-Ol 1.60E-Ol 1.S4E-03 6. 39E-04 S.67E-Ol 

4.00E+OO 3. 89E-Ol 1.SOE-Ol 2.72E-04 3.08E-04 S.39E-Ol 

S.OOE+OO 3. 68E-Ol 1.4SE-Ol 4. 82E-OS l.74E-04 S.13E-Ol 

6.00E+OO 3.47E-0l 1.4lE-0l 8.SlE-06 1.12E-04 4.88E-Ol 

7.00E+OO 3. 27E-Ol 1. 38E-Ol 1.SlE-06 8.l6E-OS 4.6SE-Ol 

8.00E+OO 3.07E-Ol 1.36E-Ol 2. 66E-07 6. 63E-OS 4. 43E-Ol 

9.00E+OO 2. 88E-Ol 1. 34E-Ol 4.70E-08 S.83E-OS 4.22E-Ol 

1.OOE+Ol 2.7lE-Ol 1. 32E-Ol O.OOE+OO S.40E-OS 4.03E-Ol 

2.00E+Ol 1.47E-Ol 1.16E-Ol O.OOE+OO 4. 38E-OS 2. 63E-Ol 

3.00E+0l 8. 34E-02 1.02E-Ol O.OOE+OO 3. 82E-OS 1. 86E-Ol 

4.00E+Ol S.OSE-02 9.0lE-02 O.OOE+OO 3. 32E-OS 1.4lE-Ol 

S.OOE+Ol 3.30E-02 7. 93E-02 O.OOE+OO 2. 89E-OS 1.12E-Ol 

6.00E+Ol 2. 33E-02 6. 98E-02 O.OOE+OO 2.S2E-OS 9.3lE-02 

7.00E+Ol 1.77E-02 6.l4E-02 O.OOE+OO 2.l9E-OS 7.9lE-02 

8.00E+Ol 1.4lE-02 S.40E-02 O.OOE+OO 1.9lE-OS 6.8lE-02 

9.00E+Ol 1.17E-02 4.7SE-02 O.OOE+OO 1.66E-OS S.92E-02 

l.OOE+02 9.9SE-03 4.l8E-02 O.OOE+OO 1.4SE-OS S.18E-02 

2.00E+02 2. 64E-03 1.lSE-02 O.OOE+OO 3.6lE-06 1.42E-02 

3.00E+02 7. 27E-04 3.lSE-03 O.OOE+OO 9.04E-07 3. 88E-03 

4.00E+02 1. 99E-04 8. SSE-04 O.OOE+OO 2. 26E-07 l.OSE-03 

S.OOE+02 S.39E-OS 2.3lE-04 O.OOE+OO S.6SE-08 2.8SE-04 

6.00E+02 l.4SE-OS 6.l9E-OS O.OOE+OO l.4lE-08 7. 64E-OS 

7.00E+02 3.90E-06 1.6SE-OS O.OOE+OO O.OOE+OO 2.04E-OS 

8.00E+02 1.04E-06 4.40E-06 O.OOE+OO O.OOE+OO S.44E-06 

9.00E+02 2. 76E-07 1.16E-06 O.OOE+OO O.OOE+OO l.44E-06 . ',: . ," 1.OOE+03 7. 32E-08 3.08E-07 O.OOE+OO O.OOE+OO 3.8lE-07 

B-3l9 
CLASS W AHAD = 1 MICRON STABLE ASTATINE 209 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 5. 19E-04 O.OOE+OO 

2.00E-01 1. 43E-03 O.OOE+OO 

3.00E-01 2. 66E-03 O.OOE+OO 

4.00E-Ol 4. 16E-03 O.OOE+OO 

5.00E-Ol 5. 89E-03 O.OOE+OO 

6.00E-Ol 7.81E-03 O.OOE+OO 

7.00E-Ol 9.89E-03 O.OOE+OO 

8.00E-Ol 1.21E-02 O.OOE+OO 

9.00E-Ol 1. 44E-02 O.OOE+OO 

1.00E+00 1. 69E-02 1. 69E-02 O.OOE+OO O.OOE+OO 

2.00E+00 2.70E-02 4. 39E-02 O.OOE+oo O.OOE+OO 

3.00E+00 2. 83E-02 7.22E-02 O.OOE+OO O.OOE+OO 

4.00E.+00 2. 75E-02 9. 97E-02 O.OOE+OO O.OOE+OO 

5.00E+00 2.62E-02 1. 26E-Ol O.OOE+OO O.OOE+OO 

6.00E+00 2. 48E-02 1. 51E-Ol O.OOE+OO O.OOE+OO 

7.00E+00 2. 34E-02 1. 74E-01 O.OOE+OO O.OOE+OO 

8.00E+00 2.20E-02 1.96E-01 O.OOE+oo O.OOE+OO 

S.OOE+OO 2.06E-02 2. 17E-Ol O.OOE+OO O.OOE+OO 

1.00E+01 1. 94E-02 2. 36E-Ol O.OOE+OO O.OOE+OO 

2.00E+01 1.05E-02 3. 76E-Ol O.OOE+OO O.OOE+OO 

3.00E+01, 5.94E-03 4. 53E-Ol O.OOE+OO O.OOE+OO 

4.00E+01' 3. 58E-03 4. 99E-Ol O.OOE+OO O.OOE+OO 

5.00E+Ol 2. 33E-03 5. 27E-Ol O.OOE+OO O.OOE+OO 

6.00E+Ol 1. 64E-03 5. 46E-01 O.OOE+OO O.OOE+OO 

7.00E+Ol 1. 24E-03 5.60E-01 O.OOE+OO O.OOE+OO 

8.00E+Ol 9. 88E-04 5.71E-Ol O.OOE+OO O.OOE+OO 

9.00E+Ol 8. 19E-04 5.80E-Ol O.OOE+OO O.OOE+OO 

1.00E+02 6. 95E-04 5. 87E-Ol O.OOE+OO O.OOE+OO 

2.00E+02 1. 84E-04 6. 25E-Ol O.OOE+OO O.OOE+OO 

3.00E+02 5.07E-05 6. 35E-Ol O.OOE+OO O.OOE+OO 

4.00E+02 1. 39E-05 6.38E-Ol O.OOE+OO O.OOE+OO 

5.00E+02 3. 76E-06 6.39E-Ol O.OOE+OO O.OOE+OO 

6.00E+02 1.01E-06 6.39E-Ol O.OOE+OO O.OOE+OO 

7.00E+02 2. 72E-07 6. 39E-Ol O.OOE+OO O.OOE+OO 

'. ",' "" 8.00E+02 7. 25E-08 6.39E-Ol O.OOE+OO O.OOE+OO 

9.00E+02 1. 93E-08 6. 39E-Ol O.OOE+OO O.OOE+OO 

B-320 
ClASS V AHA» = 1 MICRON HAI..FLlFE- 1.14E+OI DAYS RADIUM 223 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.50E-02 2.75E-OI 2.33E-OI 5.5IE-02 5.9BE-OI 

2.00E-OI 3.60E-02 2. 62E-OI 1. 95E-OI 9. 65E-02 5.B9E-OI 

3.00E-OI 3.B2E-02 2. SlE-Ol 1.63E-0l 1.2BE-0l S.BOE-OI 

4.00E-Ol 4.02E-02 2.4IE-Ol 1. 36E-Ol I.S2E-Ol 5.70E-Ol 

S.OOE-Ol 4.l9E-02 2. 32E-Ol 1.14E-0l 1.70E-Ol S.S9E-Ol 

6.00E-Ol 4.3lE-02 2. 24E-Ol 9.SlE-02 I.B4E-Ol S.47E-OI 

7.00E-Ol 4. 39E-02 2.l7E-0l -7.95E-02 1.93E-0l S.34E-OI 

B.OOE-Ol ·4.43E-02 2.lOE-Ol 6. 64E-02 1. 99E-Ol S.2lE-Ol 

9.00E-Ol 4.4SE-02 2.04E-Ol S.SSE-02 2.02E-Ol S.07E-Ol 

1.OOE+OO 4.44E-02 1.9BE-Ol 4. 64E-02 2.03E-Ol 4. 92E-OI 

2.00E+OO 3. 73E-02 1.S7E-Ol 7. 72E-03 1.42E-Ol 3. 44E-Ol 

3.00E+OO 2.92E-02 1. 33E-Ol 1.2BE-03 7.40E-02 2.3BE-Ol 

4.00E+OO 2.3lE-02 1.IBE-Ol 2.l4E-04 3. SIE-02 1. 76E-Ol 

5.00E+OO 1. BSE-02 1.07E-Ol 3.S6E-05 1. 64E-02 1. 42E-OI 

6.00E+OO 1.SOE-02 9. 79E-02 5. 92E-06 7.9BE-03 1.2IE-OI 

7.00E+OO 1. 24E-02 9.03E-02 9.B4E-07 4.IBE-03 1.07E-Ol 

B.OOE+OO I.03E-02 B.36E-02 1. 64E-07 2.45E-03 9. 64E-02 

9.00E+OO B.66E-03 7. 76E-02 2. 72E-OB 1. 63E-03 B.79E-02 

1.OOE+Ol 7. 32E-03 7.20E-02 O.OOE+OO 1. 23E-03 B.06E-02 

2.00E+Ol 2.02E-03 3. 46E-02 O.OOE+OO 4.4BE-04 3.70E-02 

3.00E+Ol B.9SE-04 1.66E-02 O.OOE+OO 2.13E-04 1.77E-02 

4.00E+Ol 4. 64E-04 7. 96E-03 O.OOE+OO I.OlE-04 B.S3E-03 

S.OOE+Ol 2. 49E-04 3.B2E-03 O.OOE+OO 4.79E-OS 4.l2E-03 

6.00E+Ol 1. 34E-04 1.B3E-03 O.OOE+OO 2. 27E-OS 1. 99E-03 

7.00E+Ol 7. 27E-OS B. BOE-04 O.OOE+OO 1.OBE-OS 9. 63E-04 

B.OOE+Ol 3. 93E-05 4. 22E-04 O.OOE+OO S.12E-06 4. 67E-04 

9.00E+Ol 2.l2E-05 2.03E-04 O.OOE+OO 2. 43E-06 2. 26E-04 

1.OOE+02 1.15E-05 9. 71E-OS O.OOE+OO 1.lSE-06 1.lOE-04 

2.00E+02 2.4lE-08 6. 23E-OB O.OOE+OO O.OOE+OO B.64E-OB 

' ... - ' 

B-32l 
CLASS II AMAD "'" 1 MICRON HALFLIFE= 1.14E+Ol DAYS RADIUM 223 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUHULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1. 87E-03 3.SSE-02 

2.00E-OI 2.09E-03 3. 99E-02 

3.00E-Ol 2. 34E-03 4.S2E-02 

4.00E-Ol 2.S9E-03 S.ISE-02 

S.OOE-OI 2. 84E-03 S.86E-02 

6.00E-OI 3.07E-03 6. 66E-02 

7.00E-Ol 3. 27E-03 7.S3E-02 

8.00E-Ol 3. 46E-03 8. 48E-02 

9.00E-OI 3. 62E-03 9. 49E-02 

1.OOE+OO 3. 77E-03 3.77E-03 I.06E-Ol 1.06E-Ol 

2.00E+OO I.08E-03 4. 63E-03 I.I8E-OI 2.17E-Ol 

3.00E+OO S.S9E-04 4.91E-03 8.S9E-02 2.90E-Ol 

4.00E+OO 3.37E-04 4. 96E-03 4.72E-02 3.20E-OI 

S.OOE+OO 2. 24E-04 4. 89E-03 2. 39E-02 3.2SE-OI 

6.00E+OO I.S9E-04 4.77E-03 1.23E-02 3.19E-OI 

7.00E+OO 1.20E-04 4.60E-03 6. 76E-03 3.07E-OI 

8.00E+OO 9. 36E-OS 4. 43E-03 4.llE-03 2.93E-0l 

9.00E+OO 7.SIE-OS 4. 24E-03 2. 78E-03 2. 78E-OI 

I.OOE+OI 6.ISE-OS 4.0SE-03 2.06E-03 2. 64E-Ol 

2.00E+OI I. 37E-OS 2.4IE-03 S.19E-04 1. SlE-OI 

3.00E+Ol S.12E-06 1.37E-03 2.20E-04 8. 46E-02 

4.00E+OI 2. 34E-06 7. 74E-04 I.03E-04 4. 72E-02 

S.OOE+OI I.12E-06 4.34E-04 4.90E-OS 2. 63E-02 

6.00E+OI S.47E-07 2. 42E-04 2.3SE-OS 1.46E-02 

7.00E+OI 2. 67E-07 I.3SE-04 1.l3E-OS 8.06E-03 

8.00E+OI I.30E-07 7.S0E-OS S.42E-06 4.4SE-03 

9.00E+O! 6. 33E-08 4.16E-OS 2.60E-06 2. 46E-03 

I.OOE+02 3.08E-08 2.30E-OS I.2SE-06 I.3SE-03 

B-322 
CLASS W AKA» = 1 MICRON HALP'LIFE- 5.84E+05 DAYS RADIUM 226 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-0l 3.52E-02 2.76E-0l 2. 35E-01 5. 54E-02 6.02E-Ol 

2.00E-Ol 3. 64E-02 2. 65E-:01 1.97E-Ol 9.77E-02 5.97E-Ol 

3.00E-Ol 3.89E-02 2. 56E-01 1.66E-0l 1.30E-Ol 5.9lE-Ol 

4.00E-Ol 4.l2E-02 2.47E-Ol 1. 39E-Ol 1. 56E-Ol 5. 84E-Ol 

5.00E-0l 4. 32E-02 2.40E-Ol 1.17E-Ol 1.76E-Ol 5. 76E-Ol 

6.00E-Ol 4. 47E-02 2. 33E-Ol 9.86E-02 1.9lE-Ol 5. 67E-Ol 

7.00E-Ol 4. 58E-02 2.27E-Ol 8. 29E-02 2.02E-Ol 5.57E-Ol 

8.00E-Ol 4. 66E-02 2. 21E-01 6.97E-02 2.09E-01 5.47E-Ol 

9.00E-Ol 4.70E-02 2.l6E-Ol 5. 86E-02 2.l4E-Ol 5.35E-Ol 

1.OOE+OO 4.7lE-02 2. llE-Ol 4. 93E-02 2.l6E-Ol 5. 23E-Ol 

2.00E+OO 4. 22E-02 1. 77E-Ol 8. 72E-03 1.6lE-0l 3. 89E-01 

3.00E+OO 3. 51E-02 1.60E-Ol 1. 54E-03 8.87E-02 2. 85E-Ol 

4.00E+OO 2.94E-02 1.50E-0l 2.72E-04 4.47E-02 2. 25E-Ol 

5.00E+OO 2.50E-02 1. 45E-O 1 4. 82E-05 2. 22E-02 1. 92E-Ol 

6.00E+OO 2.l6E-02 1.4lE-0l 8.51E-06 1. 15E-02 1.74E-Ol 

7.00E+OO 1. 89E-02 1. 38E-Ol 1.5lE-06 6.40E-03 1. 63E-Ol 

8.00E+OO 1. 68E-02 1. 36E-Ol 2. 66E-07 3.98E-03 1.57E-OI 

9.00E+OO 1. 49E-02 1. 34E-Ol 4.70E-08 2. 82E-03 1. 52E-Ol 

1.00E+Ol 1. 34E-02 1. 32E-Ol O.OOE+OO 2.25E-03 1.48E-OI 

2.00E+Ol 6. 79E-03 1. 16E-Ol O.OOE+OO 1.5lE-03 1. 25E-Ol 

3.00E+Ol 5. 52E-03 1.02E-OI O.OOE+OO 1.3lE-03 1.09E-Ol 

4.00E+Ol 5. 25E-03 9.01E-02 O.OOE+OO 1. 14E-03 9. 64E-02 

5.00E+01 5.l7E-03 7.93E-02 O.OOE+OO 9.93E-04 8. 54E-02 

6.00E+Ol 5.llE-03 6. 97E-02 O.OOE+OO 8. 65E-04 7. 57E-02 

7.00E+Ol 5.07E-03 6.l4E-02 O.OOE+OO 7.53E-04 6.72E-02 

8.00E+01 5.02E-03 5.40E-02 O.OOE+OO 6. 55E-04 5. 97E-02 

9.00E+01 4. 97E-03 4.75E-02 O.OOE+OO 5.71E-04 5.30E-02 

1.00E+02 4. 93E-03 4. 18E-02 O.OOE+OO 4. 97E-04 4. 72E-02 

2.00E+02 4.45E-03 1. 15E-02 O.OOE+OO 1.24E-04 1. 61E-02 

3.00E+02 4.04E-03 3. 15E-03 O.OOE+OO 3.lOE-05 7. 22E-03 

4.00E+02 3.70E-03 8.55E-04 O.OOE+OO 7. 76E-06 4. 57E-03 

5.00E+02 3. 43E-03 2.3lE-04 O.OOE+OO 1. 94E-06 3. 66E-03 

6.00E+02 3.2lE-03 6. 18E-05 O.OOE+OO 4.85E-07 3. 27E-03 

7.00E+02 3.03E-03 1. 65E-05 O.OOE+OO 1.2lE-07 3.04E-03 

8.00E+02 2. 87E-03 4. 39E--06 O.OOE+OO 3.03E-08 2. 88E-03 

9.00E+02 2. 75E-03 1. 16E-06 O.OOE+OO O.OOE+OO 2. 75E-03 

1.00E+03 2. 63E-03 3.07E-07 O.OOE+OO O.OOE+OO 2. 64E-03 

2.00E+03 1. 99E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 99E-03 

4.00E+03 1.40E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.40E-03 

5.00E+03 1. 22E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 22E-03 

7.00E+03 9. 62E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 62E-04 

8.00E+03 8. 64E-04 O.OOE+OO O.OOE+OO O.OOE+OO 8. 64E-04 

1.OOE+04 7.06E-04 O.OOE+OO O.OOE+OO O.OOE+OO 7.06E-04 

2.00E+04 2. 87E-04 O.OOE+OO O.OOE+OO O.OOE+OO 2. 87E-04 

B-323 
CLASS W AHAD - 1 MICRON 1IALP'LIFE= 5.84E+05 DAYS RADIUM 226 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 1. SSE-03 3.S7E-02 

2.00E-Ol 2.l2E-03 4.03E-02 

3.00E-Ol 2.3SE-03 4.60E-02 

4.00E-Ol 2. 66E-03 5.27E-02 

S.OOE-O! 2. 93E-03 6.04E-02 

6.00E-Ol 3.!SE-03 6.90E-02 

7.00E-O! 3.4lE-03 7.S6E-02 

S.OOE-Ol 3. 63E-03 S.90E-02 

9.00E-Ol 3.S2E-03 1.OOE-Ol 

!.OOE+OO 4.0lE-03 4.OlE-03 1.12E-OI I.I2E-OI 

2.00E+OO 1. 22E-03 5. 22E-03 I.33E-0l 2.45E-OI 

3.00E+OO 6.70E-04 5.S9E-03 I.03E-OI 3.4SE-OI 

4.00E+OO 4. 29E-04 6.32E-03 6.02E-02 4.08E-0l 

5.00E+OO 3.03E-04 6. 63E-03 3. 24E-02 4.4IE-OI 

6.00E+OO 2. 29E-04 6. 86E-03 I.77E-02 4.S8E-Ol 

7.00E+OO 1. 83E-04 7.04E-03 I.03E-02 4. 69E-OI 

8.00E+OO I.52E-04 7.19E-03 6.6SE-03 4.75E-OI 

9.00E+OO I.30E-04 7. 32E-03 4.80E-03 4.80E-OI 

I.OOE+OI 1.I3E-04 7.43E-03 3.7SE-03 4.S4E-Ol 

2.00E+OI . 4.62E-05 S.IIE-03 1. 75E-03 S.06E-OI 

3.00E+OI 3.16E-05 8.47E-03 1.36E-03 S.2lE-Ol 

4.00E+OI 2. 64E-05 S.76E-03 I.I6E-03 5. 34E-OI 

5.00E+OI 2. 33E-05 9.00E-03 I.02E-03 S.45E-OI 

6.00E+Ol 2.08E-05 9. 22E-03 8. 93E-04 5. 54E-O! 

7.00E+OI 1.86E-05 9.42E-03 7.87E-04 5. 62E-Ol 

8.00E+OI I.66E-05 9. 59E-03 6. 93E-04 5.70E-Ol 

9.00E+OI 1. 48E-05 9. 75E-03 6.IIE-04 5. 76E-Ol 

1.OOE+02 1. 33E-05 9.S9E-03 5.3SE-04 5.S2E-OI 

2.00E+02 4. 23E-06 1.07E-02 1.52E-04 6.l2E-Ol 

3.00E+02 1.3SE-06 I.09E-02 4.40E-05 6.21E-OI 

4.00E+02 4. 96E-07 1.lOE-02 I.39E-05 6.23E-Ol 

S.OOE+02 2.2lE-07 1.lOE-02 5.3lE-06 6.24E-Ol 

6.00E+02 !.28E-07 1.IIE-02 2.70E-06 6.24E-0l 

7.00E+02 9.0SE-08 I.llE-02 1.79E-06 6. 24E-OI 

S.OOE+02 7.17E-OS I.llE-02 I.38E-06 6. 25E-Ol 

9.00E+02 5. 98E-OS I.IIE-02 1.I4E-06 6. 25E-Ol 

1.OOE+03 5.14E-OS 1.llE-02 9. 77E-07 6.2SE-O! 

2.00E+03 2.16E-OS I.IIE-02 4.IQE-07 6. 25E-OI 

3.00E+03 1.4IE-08 1.llE-02 2.69E-07 6. 24E-Ol 

4.00E+03 1.03E-OS I.llE-02 1. 95E-07 6. 24E-OI 

B-324 
CLASS W AHAD = 1 MICRON BALFLIFE- 1.95E+03 DAYS ACTINIUM 221 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.95E-02 2. 76E-0l 2.35E-01 5.72E-02 6.3BE-01 

2.00E-Ol 6.B3E-02 2. 65E-01 1. 97E-Ol 1.05E-Ol 6.36E-Ol 

3.00E-Ol 6. 73E-02 2. 56E-01 1. 66E-01 1.45E-01 6. 34E-01 

4.00E-Ol 6. 67E-02 2.47E-Ol 1. 39E-01 1. 79E-01 6.32E-01 

5.00E-01 6.61E-02 2.40E-01 1. 17E-Ol 2.06E-Ol 6.29E-Ol 

6.00E-Ol 6.5BE-02 2. 33E-01 9.B6E-02 2. 27E-01 6. 24E-01 

7.00E-01 6. 55E-02 2.27E-01 B.29E-02 2. 43E-01 6.1BE-Ol 

B.OOE-01 6. 53E-02 2.2lE-Ol 6. 97E-02 2. 54E-01 6.l0E-Ol 

9.00E-01 6. 52E-02 2. 16E-0l 5.86E-02 2.6lE-Ol 6.0lE-Ol 

1.00E+OO 6. 51E-02 2. 11E-Ol 4. 93E-02 2. 65E-01 5.90E-01 

2.00E+OO 6. 52E-02 1.17E-Ol B.72E-03 2.03E-Ol 4. 54E-Ol 

3.00E+OO 6.S7E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3.40E-01 

4.00E+OO 6.6IE-02 1.50E-01 2.72E-04 5.72E-02 2. 74E-01 

S.OOE+OO 6. 66E-02 1. 44E-01 4.B1E-OS 2.B4E-02 2.40E-01 

6.00E+OO 6.70E-02 1.4lE-Ol 8.51E-06 1.46E-02 2. 22E-01 

7.00E+OO 6. 74E-02 1. 38E-01 1.S0E-06 S.12E-03 2. 14E-01 

8.00E+OO 6.79E-02 1.36E-01 2.66E-07 S.03E-03 2.09E-01 

9.00E+OO 6.S3E-02 1. 34E-01 4.70E-OB 3.S4E-03 2.06E-01 

I.OOE+01 6.S7E-02 1. 32E-01 O.OOE+OO 2.SIE-03 2.04E-01 

2.00E+01 7.27E-02 1.16E~OI O.OOE+OO 1.S7E-03 1.9IE-Ol 

3.00E+Ol 7.63E-02· I.02E-Ol O.OOE+OO 1.62E-03 .. 1.S0E-01 

4.00E+OI 7. 95E-02 8. 97E-02 O.OOE+OO 1.4IE-03 1. 71E-01 

5.00E+Ol 8. 24E-02 7. 89E-02 O.OOE+OO 1.13E-03 1.63E-01 

6.00E+Ol S.50E-02 6. 94E-02 O.OOE+OO 1.07E-03 1.55E-Ol 

7.00E+Ol 8.74E-02 6.lOE-02 O.OOE+OO 9. 29E-04 1.49E-Ol 

B.OOE+OI S.95E-02 5. 36E-02 O.OOE+OO S.08E-04 1.44E-Ol 

9.00E+Ol 9.l4E-02 4.7IE-02 O.OOE+OO 7.03E-04 1.39E-Ol 

1.OOE+02 9.30E-02 4. 14E-02 O.OOE+OO 6.l2E-04 1.3SE-Ol 

2.00E+02 1.02E-OI 1.13E-02 O.OOE+OO 1. 52E-04 1.14E-Ol 

3.00E+02 1.04E-Ol 3.07E-03 O.OOE+OO 3. 76E-05 1.07E-Ol 

4.00E+02 1.04E-Ol B.26E-04 O.OOE+OO 9.3lE-06 1.05E-Ol 

5.00E+02 1.03E-Ol 2.2lE-04 O.OOE+OO 2.3lE-06 1.03E-Ol 

6.00E+02 1.02E-0l 5.87E-05 O.OOE+OO S.12E-07 1.02E-Ol 

7.00E+02 1.OlE-Ol 1.SSE-05 O.OOE+OO 1. 42E-07 1.OlE-OI 

B.OOE+02 9. 93E-02 4.l0E"'06 O.OOE+OO 3.5lE-OS 9.94E-02 

9.00E+02 9.S2E-02 1.OSE-06 O.OOE+OO O.OOE+OO 9.S2E-02 

1.00E+03 9.70E-02 2.82E-07 O.OOE+OO O.OOE+OO 9.70E-02 ': ' 2.00E+03 S.60E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.60E-02 

4.00E+03 6. 77E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.77E-02 

S.OOE+03 6.0lE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.0lE-02 

7.00E+03 4. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.73E-02 

S.OOE+03 4.20E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.20E-02 

I.OOE+04 3.31E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.3lE-02 

2.00E+04 1.02E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.02E-02 

B-325 
CLASS W AHA» .. 1 MICRON HALFLIFE= 7. 95E+03 DAYS ACTINIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 49E-03 8.10E-06 

2.00E-01 2. 84E-03 1. 64E-04 

3.00E-Ol 3.87E-03 8. 29E-04 

4.00E-Ol 4. 65E-03 2. 42E-03 

5.00E-Ol 5. 25E-03 5. 28E-03 

6.00E-Ol 5.70E-03 9.61E-03 

7.00E-Ol 6.05E-03 1.55E-02 

8.00E-Ol 6.31E-03 2.30E-02 

9.00E-01 6. 51E-03 3. 19E-02 

1.00E+00 6. 67E-03 6. 67E-03 4.21E-02 4. 21E-02 

2.00E+00 5.00E-04 7. 17E-03 1.35E-01 1.77E-01 

3.00E+00 8.49E-05 7. 25E-03 1. 14E-Ol 2. 92E-01 

4.00E+00 5. 58E-05 7.31E-03 6. 64E-02 3.58E-01 

5.00E+00 5. 28E-05 7. 36E-03 3.41E-02 3. 92E-01 

6.00E+00 5. 19E-05 7.41E-03 1. 71E-02 4.09E-01 

7.00E+00 5. 12E-05 7. 46E-03 8.77E-03 4. 18E-01 

8.00E+00 5.07E-05 7. 51E-03 4.83E-03 4.22E-Ol 

9.00E+00 5.02E-05 7. 56E-03 2. 96E-03 4. 25E-Ol 

1.00E+Ol 4. 98E-05 7. 61E-03 2.06E-03 4. 27E-Ol 

2.00E+01 4. SSE-OS 8.08E-03 1.08E-03 4. 39E-Ol 

3.00E+Ol 4. 16E-05 8.50E-03 9.41E-04 4.49E-Ol 

4.00E+Ol 3.80E-05 8. 89E-03 8. 18E-04 4. 57E-01 

5.00E+01 3. 47E-05 9. 25E-03 7. 12E-04 4. 65E-01 

6.00E+01 3. 17E-05 9. 57E-03 6. 19E-04 4. 71E-01 

7.00E+01 2.89E-05 9.86E-03 5.39E-04 4.76E-01 

8.00E+Ol 2. 64E-05 1.01E-02 4. 68E-04 4.81E-01 

9.00E+01 2. 41E-05 1.04E-02 4.07E-04 4. 85E-Ol 

1.00E+02 2.20E-05 1.06E-02 3.54E-04 4. 88E-01 

2.00E+02 9. 56E-06 1.20E-02 8.78E-05 5.03E-01 

3.00E+02 5. 35E-06 1. 26E-02 2. 18E-05 5.03E-01 

4.00E+02 4.00E-06 1.29E-02 5. 39E-06 5.00E-01 

5.00E+02 3. 57E-06 1. 32E-02 1. 34E-06 4. 96E-01 

6.00E+02 3.41E-06 1. 34E-02 3.31E-07 4.91E-01 

7.00E+02 3. 34E-06 1. 36E-02 8.21E-08 4. 87E-01 .- .. 8.00E+02 3. 29E-06 1. 38E-02 2.03E-08 4.83E-01 ,.", 

9.00E+02 3. 24E-06 1.40E-02 O.OOE+OO 4. 79E-01 

1.00E+03 3.20E-06 1.42E-02 O.OOE+OO 4. 75E-01 

2.00E+03 2. 82E-06 1. 59E-02 O.OOE+OO 4. 35E-01 

4.00E+03 2. 19E-06 1. 79E-02 O.OOE+OO 3.65E-Ol 

8.00E+03 1. 33E-06 1. 84E-02 O.OOE+OO 2. 58E-01 

1.00E+04 1.03E-06 1. 76E-02 O.OOE+OO 2. 17E-01 

B-326 
CLASS W AMAD = 1 MICRON BALFLIFE= 1.87E+OI DAYS THORIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6. 99E-02 2.7SE-0l 2. 34E-01 S.69E-02 6.36E-01 

2.00E-01 6.90E-02 2. 63E-01 1. 96E-01 1.0SE-01 6. 33E-01 

3.00E-01 6.S1E-02 2.S3E-01 1.64E-01 1.44E-01. 6.29E-01 

4.00E-OI 6. 73E-02 2. 44E-OI 1.37E-OI 1.76E-OI 6. 24E-01 

S.OOE-OI 6.6SE-02 2.3SE-OI 1.ISE-OI 2.02E-OI 6.19E-OI 

6.00E-OI 6.S9E-02 2. 28E-OI 9.6SE-02 2. 22E-OI 6.12E-OI 

7.00E-OI 6.S3E-02 2.2IE-OI S.OSE-02 2. 37E-OI 6.03E-OI 

S.OOE-OI 6.4SE-02 2.14E-OI 6. 77E-02 2. 47E-OI S.94E-OI 

9.00E-OI 6. 43E-02 2.09E-OI S.67E-02 2.S3E-01 S.S2E-OI 

I.OOE+OO 6.3SE-02 2.03E-OI 4.7SE-02 2.S6E-OI S.70E-OI 

2.00E+OO 6.07E-02 1.6SE-OI S.lOE-03 1. S9E-0l 4. 22E-OI 

3.00E+OO S.S6E-02 1. 43E-OI 1.3SE-03 I.OIE-OI 3.04E-OI 

4.00E+OO S.67E-02 1.30E-OI 2. 35E-04 4.93E-02 2. 36E-OI 

S.OOE+OO S.SOE-02 1.20E-OI 4.00E-OS 2. 37E-02 1. 99E-OI 

6.00E+OO S.33E-02 I.BE-OI 6.S2E-06 1. 17E-02 1.7SE-OI 

7.00E+OO S.17E-02 1.07E-OI 1. 16E-06 6.2SE-03 1.6SE-Ol 

S.OOE+OO S.02E-02 I.OIE-OI 1.9SE-07 3.7SE-03 I.SSE-OI 

9.00E+OO 4.S6E-02 9.60E-02 3. 37E-OS 2.S4E-03 1.47E-OI 

1.00E+Ol 4.71E-02 9.12E-02 O.OOE+OO 1.94E-03 1.40E-OI 

2.00E+OI 3. 44E-02 S.S4E-02 O.OOE+OO S.93E-04 9.07E-02 

3.00E+Ol 2. 49E-02 3.37E-02 O.OOE+OO S.37E-04 S.9IE-02 

4.00E+OI 1. 79E-02 2.0SE-02 O.OOE+OO 3. 23E-04 3.S7E-02 

S.OOE+01 1.2SE-02 1. 24E-02 O.OOE+OO 1.94E-04 2.S4E-02 

6.00E+Ol 9.11E-03 7.S6E-03 O.OOE+OO 1.17E-04 1.6SE-02 

7.00E+Ol 6. 46E-03 4.60E-03 O.OOE+OO 7.01E-OS 1. l1E-02 

S.OOE+Ol 4.S6E-03 2. 79E-03 O.OOE+OO 4.21E-OS 7.39E-03 

9.00E+Ol 3. 21E-03 1.70E-03 O.OOE+OO 2. S3E-OS 4. 93E-03 

1.00E+02 2. 26E-03 1.03E-03 O.OOE+OO I.S2E-OS 3.30E-03 

2.00E+02 6.03E-OS 7.01E-06 O.OOE+OO 9.3SE-OS 6.74E-OS 

3.00E+02 I.S0E-06 4. 72E-OS O.OOE+OO O.OOE+OO 1.SSE-06 

4.00E+02 3.64E-OS O.OOE+OO O.OOE+OO O.OOE+OO 3. 64E-OS 

B-327 
CLASS W AMAD = 1 MICRON HALFLIFE= 1.87E+OI DAYS THOR.IUM 227 

TU1E AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 7.92E-04 1.60E-05 

2.00E-01 1.60E-03 1. 79E-04 

3.00E-01 2.30E-03 8. 43E-04 

4.00E-01 2. 91E-03 2.41E-03 

S.OOE-01 3.43E-03 5. 22E-03 

6.00E-01 3. 88E-03 9.44E-03 

7.00E-01 4.27E-03 1. 52E-02 

8.00E-01 4.60E-03 2. 24E-02 

9.00E-01 4. 89E-03 3.09E-02 

1.00E+OO S.14E-03 5. 14E-03 4.07E-02 4.07E-02 

2.00E+OO 1. 32E-03 6.27E-03 1.26E-0l 1.65E-01 

3.00E+OO 3. 66E-04 6.41E-03 1.02E-01 2. 61E-01 

4.00E+OO I.33E-04 6.3IE-03 5.73E-02 3.09E-01 

S.OOE+OO 7.SIE-OS 6. 16E-03 2. 84E-02 3.26E-OI 

6.00E+OO S.93E-OS S.99E-03 I.37E-02 3.28E-OI 

7.00E+OO S.37E-OS S.83E-03 6.17E-03 3. 23E-OI 

8.00E+OO S.08E-OS S.67E-03 3.60E-03 3.ISE-OI 

9.00E+OO 4. 85E-OS 5.5IE-03 2.13E-03 3.05E-OI 

I.OOE+01 4. 64E-05 S.36E-03 1. 43E-03 2. 96E-OI 

2.00E+01 3.0SE-OS 4.01E-03 S.18E-04 2.lOE-Ol 

3.00E+01 2.00E-OS 2.97E-03 3. 11E-04 1. 48E-01 

4.00E+01 I. 32E-OS 2. 19E-03 1. 87E-04 I.04E-01 

S.OOE+01 8. 66E-06 1.60E-03 1. 12E-04 7. 33E-02 

6.00E+01 S.71E-06 1. 16E-03 6. 76E-OS S.I4E-02 

7.00E+01 3. 77E-06 8. 42E-04 4.06E-OS 3.59E-02 

8.00E+01 2. 49E-06 6.07E-04 2. 44E-05 2.S1E-02 

9.00E+01 I.65E-06 4. 36E-04 1. 47E-OS 1.7SE-02 

1.00E+02 1.09E-06 3. 12E-04 8. 83E-06 1. 21E-02 

2.00E+02 1.98E-08 9. 98E-06 5.46E-08 3.11E-04 

., ... .; 

B-328 
CLASS W AHA» = 1 MICRON HALFLU'£= 2.81£+07 DAYS THORIUM. 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7.02E-02 2. 76E-Ol 2.35E-Ol 5.12E-02 6. 38E-Ol 

2.00E-Ol 6. 95E-02 2. 65E-01 1. 97E-Ol 1.05E-Ol 6. 37E-01 

3.00E-Ol 6. 88E-02 2.56E-Ol 1.66E-01 1.46E-01 6. 36E-Ol 

4.00E-Ol 6.83E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.34E-01 

5.00E-Ol 6.78E-02 2.40E-Ol 1. 17E-Ol 2.06E-01 6.30E-Ol 

6.00E-Ol 6. 74E-02 2. 33E-01 9. 86E-02 2. 27E-Ol 6. 26E-01 

7.00E-Ol 6.70E-02 2.27E-Ol 8. 29E-02 2. 43E-01 6. 19E-Ol 

8.00E-Ol 6. 67E-02 2.21E-Ol 6.97E-02 2. 54E-Ol 6. 11E-Ol 

9.00E-Ol 6. 65E-02 2. 16E-Ol 5.86E-02 2.61E-01 6.02E-Ol 

1.00E+00 6. 62E-02 2. 11E-01 . 4.93E-02 2. 65E-Ol 5. 92E-Ol 

2.00E+00 6. 53E-02 1. 77E-01 8.12E-03 2.04E-01 4. 55E-Ol 

3.00E+00 6. 54E-02 1.60E-01 1.54E-03 1. 13E-01 3.40E-01 

4.00E+00 6. 58E-02 1.50E-Ol 2. 12E-04 5.72E-02 2. 74E-01 

5.00E+00 6. 62E-02 1. 45E-01 4. 82E-05 2. 85E-02 2. 39E-01 

6.00E+00 6. 66E-02 1.41E-01 8. 51E-06 1.47E-02 2. 22E-01 

7.00E+00 6.70E-02 1. 38E-01 1.51E-06 8. 14E-03 2. 13E-01 

8.00E+00 6. 75E-02 1.36E-01 2.66E-07 5.04E-03 2.08E-Ol 

9.00E+00 6. 79E-02 1. 34E-01 4.70E-08 3. 55E-03 2.05E-01 

1.00E+01 6. 83E-02 1. 32E-01 O.OOE+OO 2.82E-03 2.03E-01 

2.00E+01 7.21E-02 1. 16E-01 O.OOE+OO 1. 87E-03 1.90E-Ol 

3.00E+01 7.56E-02 1.02E-01 O.OOE+OO 1.63E-03 1.80E-01 

4.00E+Ol 7.87E-02 9.01E-02 O.OOE+OO 1. 42E-03 1.70E-01 

5.00E+Ol 8. 15E-02 7. 93E-02 O.OOE+OO 1.23E-03 1. 62E-Ol 

6.00E+Ol 8.40E-02 6. 98E-02 O.OOE+OO 1.08E-03 1. 55E-01 

7.00E+01 8. 62E-02 6. 14E-02 O.OOE+OO 9.36E-04 1.49E-01 

8.00E+Ol 8. 82E-02 5.40E-02 O.OOE+OO 8. 15E-04 1. 43E-01 

9.00E+Ol 8.99E-02 4.75E-02 O.OOE+OO 7.09E-04 1. 38E-01 

1.00E+02 9. 15E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1. 34E-01 

2.00E+02 9. 92E-02 1.15E-02 O.OOE+OO 1.54E-04 1. 11E-Ol 

3.00E+02 1.00E-Ol 3. 15E-03 O.OOE+OO 3. 86E-05 1.03E-Ol 

4.00E+02 9.85E-02 8. 55E-04 O.OOE+OO 9.65E-06 9. 94E-02 

5.00E+02 9. 65E-02 2. 31E-04 O.OOE+OO 2.41E-06 9. 68E-02 

6.00E+02 9. 45E-02 6. 19E-05 O.OOE+OO 6.03E-07 9. 45E-02 

7.00E+02 9. 25E-02 1. 65E-05 O.OOE+OO 1.51E-07 9. 25E-02 

8.00E+02 9.06E-02 4.40E-06 O.OOE+OO 3.77E-08 9.06E-02 

, . . , 9.00E+02 8. 89E-02 1. 16E-06 O.OOE+OO O.OOE+OO 8. 89E-02 . . • ~ , .' :,' <' • 1.00E+03 8.12E-02 3.08E-07 O.OOE+OO O.OOE+OO 8.12E-02 

2.00E+03 7.49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.49E-02 

4.00E+03 6.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.05E-02 

5.00E+03 5. 52E-02 O.OOE+OO O.OOE+OO O.OOE+OO 5. 52E-02 

7.00E+03 4. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.63E-02 

8.00E+03 4. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 25E-02 

1.00E+04 3.57E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 57E-02 

2.00E+04 1.50E-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.50E-02 

B-329 
CLASS W AHAD = 1 HICB..ON HALFLIFE= 2.81B+07 DAYS THORIUM 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 7.95E-04 1.60E-05 

2.00E-Ol 1. 61E-03 1.80E-04 

3.00E-Ol 2.33E-03 8. 52E-04 

4.00E-Ol 2. 95E-03 2. 45E-03 

5.00E-Ol 3.49E-03 5.31E-03 

6.00E-Ol 3. 97E-03 9. 65E-03 

7.00E-Ol 4. 38E-03 1.56E-02 

8.00E-Ol 4. 74E-03 2.30E-02 

9.00E-Ol 5.06E-03 3.20E-02 

1.00E+00 5. 33E-03 5. 33E-03 4. 22E-02 4. 22E-02 

2.00E+00 1.42E-03 6.76E-03 1.35E-Ol 1.78E-Ol 

3.00E+00 4.09E-04 7. 17E-03 1. 14E-Ol 2. 92E-Ol 

4.00E+00 1. 54E-04 7. 32E-03 6.65E-02 3. 58E-Ol 

5.00E+00 9.04E-05 7.41E-03 3.42E-02 3. 93E-Ol 

6.00E+00 7.40E-05 7. 49E-03 1.71E-02 4.IOE-01 

7.00E+00 6. 96E-05 7. 55E-03 8. 78E-03 4. 18E-Ol 

8.00E+00 6.83E-05 7. 62E-03 4.84E-03 4.23E-Ol 

9.00E+00 6.77E-05 7. 69E-03 2. 97E-03 4. 26E-Ol 

1.00E+Ol 6.72E-05 7.76E-03 2.07E-03 4.28E-Ol 

2.00E+Ol 6. 39E-05 8.41E-03 1.09E-03 4.41E-Ol 

3.00E+01 6.08E-05 9.03E-03 9.45E-04 4.51E-Ol 

4.00E+Ol 5. 79E-05 9. 63E-03 8. 22E-04 4. 59E-Ol 

5.00E+Ol 5. 52E-05 1.02E-02 7.16E-04 4.67E-Ol 

6.00E+Ol 5. 27E-05 1.07E-02 6. 23E-04 4. 74E-Ol 

7.00E+Ol 5.03E-05 1. 12E-02 5.43E-04 4. 79E-Ol 

8.00E+Ol 4. 82E-05 1. 17E-02 4. 73E-04 4. 84E-Ol 

9.00E+Ol 4. 62E-05 1.22E-02 4. 11E-04 4. 89E-Ol 

1.00E+02 4. 44E-05 1. 27E-02 3. 58E-04 4.93E-Ol 

2.00E+02 3. 25E-05 1.64E-02 8.98E-05 5. 12E-Ol 

3.00E+02 2. 72E-05 1. 94E-02 2. 26E-05 5. 17E-Ol 

4.00E+02 2.43E-05 2. 19E-02 5.83E-06 5. 18E-Ol 

5.00E+02 2. 24E-05 2. 43E-02 1. 62E-06 5. 18E-Ol 

6.00E+02 2.08E-05 2. 64E-02 5.57E-07 5. 18E-Ol 

7.00E+02 1. 94E-05 2. 84E-02 2.81E-07 5. 18E-Ol . ", 8.00E+02 1. 82E-05 3.03E-02 2.03E-07 5. 18E-Ol 

9.00E+02 1.70E-05 3. 21E-02 1. 76E-07 5. 19E-Ol 

1.00E+03 1.60E-05 3. 37E-02 1.61E-07 5. 19E-Ol 

2.00E+03 9. 63E-06 4.60E-02 9. 63E-08 5. 19E-Ol 

4.00E+03 5. 68E-06 6.04E-02 5.68E-08 5.19E-Ol 

8.00E+03 3. 69E-06 7. 84E-02 3. 69E-08 5. 19E-Ol 

1.00E+04 3.09E-06 8.52E-02 3.09E-08 5. 19E-Ol 

B-330 
CLASS W AMAD = 1 MICRON HALFLIFE= 5.13E+ 12 DAYS THORIUM 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.02E-02 2.76E-Ol 2.3SE-Ol S.72E-02 6.3BE-Ol 

2.00E-Ol 6.9SE-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 37E-Ol 

3.00E-Ol 6.BBE-02 2.S6E-Ol 1. 66E-Ol 1.46E-Ol 6.36E-Ol 

4.00E-Ol 6.B3E-02 2.47E-Ol 1. 39E-Ol 1. 79E-Ol 6. 34E-Ol 

S.OOE-Ol 6.7BE-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6.30E-Ol 

6.00E-Ol 6. 74E-02 2. 33E-Ol 9.B6E-02 2.27E-Ol 6.26E-Ol 

7.00E-Ol 6.70E-02 2.27E-Ol B.29E-02 2. 43E-Ol 6.l9E-Ol 

B.OOE-Ol 6.67E-02 2.2lE-Ol 6. 97E-02 2.S4E-Ol 6.11E-Ol 

9.00E-Ol 6.6SE-02 2.l6E-Ol S. B6E-02 2.6lE-Ol 6.02E-Ol 

1.OOE+OO 6. 62E-02 2. llE-Ol 4. 93E-02 2.6SE-Ol S.92E-Ol 

2.00E+OO 6.S3E-02 1.77E-Ol B.72E-03 2.04E-Ol 4.SSE-Ol 

3.00E+OO 6.S4E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3.40E-Ol 

4.00E+OO 6.SBE-02 1. SOE-Ol 2. 72E-04 S.72E-02 2. 74E-Ol 

S.OOE+OO 6.62E-02 1.4SE-Ol 4.B2E-OS 2. BSE-02 2. 39E-Ol 

6.00E+OO 6. 66E-02 1.4lE-Ol B.SlE-06 1.47E-02 2.22E-Ol 

7.00E+OO 6.70E-02 1.3BE-Ol 1.SlE-06 B.14E-03 2.l3E-Ol 

B.OOE+OO 6.7 SE-02 1.36E-Ol 2. 66E-07 S.04E-03 2.0BE-Ol 

9.00E+OO 6. 79E-02 1. 34E-Ol 4.70E-OB 3.SSE-03 2.0SE-Ol 

1.OOE+Ol 6.B3E-02 1.32E-Ol O.OOE+OO 2.B2E-03 2.03E-Ol 

2.00E+Ol 7.2lE-02 1.16E-Ol O.OOE+OO 1.B7E-03 1.90E-Ol 

3.00E+Ol 7. S6E-02 1.02E-Ol O.OOE+OO 1.63E-03 1. BOE-Ol 

4.00E+Ol 7.B7E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1.70E-Ol 

S.OOE+Ol B.lSE-02 7. 93E-02 O.OOE+OO 1.23E-03 1.62E-Ol 

6.00E+Ol· B.40E-02 6.9BE-02 O.OOE+OO 1.OBE-03 1.SSE-Ol 

7.00E+Ol B.62E-02 6.l4E-02 O.OOE+OO 9.36E-04 1.49E-Ol 

B.OOE+Ol B.B2E-02 S.40E-02 O.OOE+OO B.lSE-04 1.43E-Ol 

9.00E+Ol B.99E-02 4.7SE-02 O.OOE+OO 7.09E-04 1.3BE-Ol 

1.OOE+02 9.lSE-02 4.lBE-02 O.OOE+OO 6.l7E-04 1. 34E-Ol 

2.00E+02 9. 92E-02 1.lSE-02 O.OOE+OO 1. S4E-04 1.llE-Ol 

3.00E+02 1.OOE-Ol 3.lSE-03 O.OOE+OO 3.B6E-OS 1.03E-Ol 

4.00E+02 9.BSE-02 B. SSE-04 O.OOE+OO 9.6SE-06 9. 94E-02 

S.OOE+02 9.6SE-02 2.3lE-04 O.C;>OE+OO 2.4lE-06 9.6BE-02 

6.00E+02 9.4SE-02 6.l9E-OS O.OOE+OO 6.03E-07 9.4SE-02 

7.00E+02 9.2SE-02 1.6SE-OS O.OOE+OO 1.SlE-07 9.2SE-02 

B.OOE+02 9.06E-02 4.40E"'06 O.OOE+OO 3. 77E-OB 9.06E-02 

9.00E+02 B.B9E-02 1.16E-06 O.OOE+OO O.OOE+OO B.B9E-02 '. -: . 1.OOE+03 B.72E-02 3.0BE-07 O.OOE+OO O.OOE+OO B.72E-02 , . '- :', 

2.00E+03 7.49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 49E-02 

4.00E+03 6.0SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 6.0SE-02 

S.OOE+03 S.S2E-02 O.OOE+OO O.OOE+OO O.OOE+OO S.S2E-02 

7.00E+03 4. 63E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 63E-02 

B.OOE+03 4.2SE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.2SE-02 

·1.OOE+04 3.S7E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3.S7E-02 

2.00E+04 1.SOE-02 O.OOE+OO O.OOE+OO O.OOE+OO 1.SOE-02 

B-33l 
CLASS W AHA» = 1 MICRON BALFLIFE= 5.13E+12 DAYS mORIUH 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 7.9SE-04 1.60E-OS 

2.00E-Ol 1.61E-03 1. BOE-04 

3.00E-Ol 2. 33E-03 B. S2E-04 

4.00E-Ol 2.9SE-03 2.4SE-03 

S.OOE-OI 3. 49E-03 S.3IE-03 

6.00E-Ol 3. 97E-03 9.6SE-03 

7.00E-OI 4.3BE-03 1. S6E-02 

8.00E-OI 4. 74E-03 2.30E-02 

9.00E-OI 5.06E-03 3.20E-02 

I.OOE+OO S.33E-03 S.33E-03 4. 22E-02 4. 22E-02 

2.00E+OO 1.42E-03 6. 76E-03 1.3SE-OI 1. 78E-Ol 

3.00E+OO 4.09E-04 7.17E-03 1.14E-OI 2. 92E-Ol 

4.00E+OO I.S4E-04 7. 32E-03 6.6SE-02 3. S8E-OI 

S.OOE+OO 9.04E-05 7.4IE-03 3. 42E-02 3. 93E-OI 

6.00E+OO 7.40E-OS 7. 49E-03 I.7IE-02 4. IOE-Ol 

7.00E+OO 6.96E-OS 7. 55E-03 8.7BE-03 4.1BE-Ol 

8.00E+OO 6.B3E-05 7. 62E-03 4. B4E-03 4.23E-OI 

9.00E+OO 6.77E-05 7. 69E-03 2. 97E-03 4~26E-Ol 

I.OOE+OI 6. 72E-05 7. 76E-03 2.07E-03 4. 28E-Ol 

2.00E+OI 6. 39E-05 B.4IE-03 1.09E-03 4.4IE-OI 

3.00E+OI 6.0BE-05 9.03E-03 9.4SE-04 4.5IE-Ol 

4.00E+OI 5. 79E-05 9. 63E-03 B.22E-04 4. 59E-OI 

5.00E+OI 5. 52E-OS I.02E-02 7.16E-04 4. 67E-OI 

6.00E+OI 5. 27E-OS 1.07E-02 6. 23E-04 4. 74E-OI 

7.00E+OI S.03E-OS 1.12E-02 S.43E-04 4. 79E-OI 

8.00E+OI 4.B2E-OS 1.17E-02 4. 73E-04 4.B4E-OI 

9.00E+OI 4. 62E-05 1. 22E-02 4. IIE-04 4. 89E-OI 

I.OOE+02 4. 44E-05 I. 27E-02 3. 58E-04 4. 93E-OI 

2.00E+02 3.2SE-05 I. 64E-02 B.9BE-OS S.12E-OI 

3.00E+02 2.72E-05 I. 94E-02 2. 26E-05 5.17E-OI 

4.00E+02 2.43E-05 2.19E-02 5.83E-06 5.IBE-OI 

5.00E+02 2. 24E-05 2. 43E-02 1. 62E-06 5.IBE-OI 

6.00E+02 2.08E-05 2. 64E-02 5.57E-07 5.18E-OI 

7.00E+02 I. 94E-OS 2.B4E-02 2.BIE-07 S.18E-OI 

8.00E+02 I. 82E-05 3.03E-02 2.03E-07 5.IBE-OI 

9.00E+02 1.70E-05 3.21E-02 1. 76E-07 S.19E-OI 

I.OOE+03 1.60E-OS 3. 37E-02 I.6IE-07 5.19E-OI 

2.00E+03 9. 63E-06 4.60E-02 9. 63E-OB 5.19E-OI 

4.00E+03 S.68E-06 6.04E-02 S.6BE-OB S.19E-OI 

8.00E+03 3. 69E-06 7.B5E-02 3. 69E-OB 5.19E-OI 

1.00E+04 3.10E-06 B.S2E-02 3.lOE-OB S.19E-OI 

B-332 
CLASS W AHAD - 1 MICRON HALFLIFE= 2.4lE+Ol DAYS THORIUM 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7.00E-02 2. 76E-01 2. 34E-01 5.70E-02 6.36E-01 

2.00E-01 6.9IE-02 2.64E-Ol 1. 96E-Ol I.05E-Ol 6. 34E-01 

3.00E-OI 6. 82E-02 2. 53E-01 1.64E-01 1.44E-Ol 6. 31E-OI 

4.00E-01 6. 75E-02 2. 44E-OI 1. 38E-OI 1. 77E-01 6. 27E-01 

5.00E-01 6.68E-02 2.36E-01 1. 16E-0l 2.03E-01 6.21E-Ol 

6.00E-OI 6. 62E-02 2. 29E-Ol 9. 69E-02 2. 23E-01 6. 15E-01 

7.00E-OI 6. 57E-02 2.22E-01 8.13E-02 2.38E-OI 6.07E-Ol 

8.00E-Ol 6. 52E-02 2. 16E-01 6. 82E-02 2. 48E-01 5. 97E-01 

9.00E-Ol 6.48E-02 2.lOE-0l 5. 71E-02 2.55E-Ol 5. 87E-OI 

1.00E+OO 6. 44E-02 2.05E-01 4. 79E-02 2. 58E-Ol 5. 75E-01 

2.00E+OO 6. 17E-02 1.67E-01 8. 23E-03 1.92E-0l 4. 29E-Ol 

3.00E+OO 6.00E-02 1.47E-Ol 1.41E-03 1.04E-OI 3. 12E-Ol 

4.00E+OO 5. 86E-02 1.34E-01 2. 43E-04 5.lOE-02 2. 44E-OI 

5.00E+OO 5. 73E-02 1. 25E-Ol 4.17E-05 2. 47E-02 2.07E-Ol 

6.00E+OO 5. 61E-02 1. 19E-0l 7. 16E-06 1.23E-02 1.87E-01 

7.00E+OO 5. 48E-02 1.l3E-Ol I. 23E-06 6. 65E-03 1. 74E-OI 

8.00E+OO 5.36E-02 1.08E-Ol 2.11E-07 4.00E-03 1. 66E-01 

9.00E+OO 5. 24E-02 1.03E-01 3. 63E-08 2. 74E-03 1.S9E-Ol 

1.00E+01 5.12E-02 9.91E-02 O.OOE+OO 2.llE-03 1.52E-01 

2.00E+01 4.06E-02 6.S4E-02 O.OOE+OO 1.05E-03 1.07E-01 

3.00E+01 3. 19E-02 4. 32E-02 O.OOE+OO 6.88E-04 7.S8E-02 

4.00E+01 2. 49E-02 2. 85E-02 O.OOE+OO 4.49E-04 5. 39E-02 

5.00E+01 1. 93E-02 1.88E-02 O.OOE+OO 2.93E-04 3.85E-02 

6.00E+01 1.S0E-02 1. 24E-02 O.OOE+OO 1.91E-04 2. 76E-02 

7.00E+01 1.1SE-02 8.20E-03 O.OOE+OO 1.25E-04 1.98E-02 

8.00E+Ol 8. 83E-03 5.4IE-03 O.OOE+OO 8. 16E-OS 1. 43E-02 

9.00E+01 6.76E-03 3.S7E-03 O.OOE+OO 5.33E-OS 1.04E-02 

1.00E+02 5. 16E-03 2. 35E-03 O.OOE+OO 3. 48E-05 7.S5E-03 

2.00E+02 3.1SE-04 3. 66E-05 O.OOE+OO 4.90E-07 3. 52E-04 

3.00E+02 1. 79E-05 5. 64E-07 O.OOE+OO O.OOE+OO 1.85E-05 

4.00E+02 9. 94E-07 O.OOE+OO O.OOE+OO O.OOE+OO 9. 94E-07 

5.00E+02 5. 49E-08 O.OOE+OO O.OOE+OO O.OOE+OO 5. 49E-OB 

.: . .,. 

B-333 
CLASS W AHA» = 1 MICRON BALP'LIFE= 2.41B+Ol DAYS mORIUM 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 7. 93E-04 I.60E-OS 

2.00E-OI I.60E-03 1. 79E-04 

3.00E-OI 2.3IE-03 S.4SE-04 

4.00E-OI 2. 92E-03 2.42E-03 

S.OOE-OI 3. 44E-03 S.24E-03 

6.00E-OI 3.90E-03 9. 49E-03 

7.00E-OI 4. 29E-03 I.S3E-02 

S.OOE-OI 4. 63E-03 2.2SE-02 

9.00E-OI 4.93E-03 3.lIE-02 

I.OOE+OO S.IBE-03 S.ISE-03 4.lOE-02 4. IOE-02 

2.00E+OO I.3SE-03 6.3SE-03 I.2SE-OI I.6BE-OI 

3.00E+OO 3.7SE-04 6.S7E-03 I.OSE-OI 2. 68E-OI 

4.00E+OO I.3BE-04 6.S3E-03 S.92E-02 3.19E-OI 

S.OOE+OO 7. 83E-OS 6. 42E-03 2. 96E-02 3.40E-OI 

6.00E+OO 6. 23E-OS 6.30E-03 1. 44E-02 3.4SE-OI 

7.00E+OO S.69E-OS 6.IBE-03 7.IBE-03 3. 42E-OI 

B.OOE+OO s.42E-OS 6.06E-03 3.B4E-03 3. 36E-OI 

9.00E+OO S.22E-OS S.94E-03 2. 29E-03 3.29E-OI 

1.00E+OI S.04E-OS S.B2E-03 1. SSE-03 3.2IE-aI 

2.00E+OI 3.S9E-OS 4. 73E-03 6.lIE-04 2.4BE-OI 

3.00E+0l 2.S7E-OS 3. BIE-03 3.99E-04 I.90E-OI 

4.00E+OI I.B3E-OS 3.0SE-03 2.60E-04 I.4SE-OI 

S.OOE+OI I.3IE-OS 2. 42E-03 I.70E-04 1.1IE-OI 

6.00E+OI 9.3BE-06 1.9IE-03 I.llE-04 B.43E-02 

7.00E+OI 6. 72E-06 1. SOE-03 7.2SE-OS 6.40E-02 

B.OOE+OI 4.B3E-06 I.IBE-03 4. 73E-OS 4. BSE-02 

9.00E+OI 3.47E-06 9.17E-04 3.09E-OS 3. 67E-02 

I.OOE+02 2.S0E-06 7.13E-04 2.02E-OS 2.7BE-02 

2.00E+02 1.03E-07 S.2IE-OS 2. BSE-07 1.63E-03 

B-334 
CLASS W AHA» ... 1 MICRON BALFLlFE- 1.20E+07 DAYS PROTACTINIUM 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 6.45E-02 2.76E-0l 2.35E-0l 5.72E-02 6.33E-Ol 

2.00E-OI 5. 88E-02 2. 65E-OI I.97E-OI I.05E-OI 6. 27E-OI 

3.00E-OI S.43E-02 2.S6E-OI I.66E-Ol I.45E-Ol 6.2IE-OI 

4.00E-Ol S.IOE-02 2. 47E-OI 1. 39E-OI 1. 79E-Ol 6.16E-OI 

5.00E-OI 4.85E-02 2.40E-0l I.I7E-0l 2.06E-Ol 6.llE-0l 

6.00E-Ol 4. 65E-02 2. 33E-OI 9. 86E-02 2. 27E-OI 6.0SE-OI 

7.00E-OI 4.5lE-02 2.27E-Ol 8. 29E-02 2. 43E-OI 5. 97E-Ol 

8.00E-OI 4.40E-02 2.2IE-OI 6. 97E-02 2. 54E-OI 5. 88E-OI 

9.00E-Ol 4.3lE-02 2.16E-0l 5.86E-02 2.6IE-OI S.79E-OI 

I.OOE+OO 4.2SE-02 2.llE-OI 4. 93E-02 2. 65E-OI S.68E-Ol 

2.00E+OO 4.04E-02 I.77E-Ol 8.72E-03 2.03E-Ol 4.30E-Ol 

3.00E+OO 4.00E-02 I.60E-Ol 1. 54E-03 1. l3E-OI 3.lSE-OI 

4.00E+OO 3. 98E-02 1.50E-0l 2.72E-04 5.72E-02 2. 48E-OI 

S.OOE+OO 3. 97E-02 1.4SE-Ol 4. 82E-05 2. 85E-02 2.l3E-OI 

6.00E+OO 3.95E-02 I.4IE-Ol 8.5IE-06 I.47E-02 1.95E-OI 

7.00E+OO 3. 94E-02 I.38E-OI 1.SIE-06 8.l3E-03 1. 86E-OI 

8.00E+OO 3. 93E-02 I.36E-0l ,2.66E-07 5.03E-03 I.80E-OI 

9.00E+OO 3. 92E-02 1. 34E-OI 4.70E-08 3. 54E-03 1. 77E-OI 

I.OOE+Ol 3.9lE-02 1.32E-0l O.OOE+OO 2.8lE-03 I.74E-OI 

2.00E+OI 3.B9E-02 1.I6E-OI O.OOE+OO 1. 87E-03 1.57E-OI 

3.00E+OI 3. 94E-02 I.02E-OI O.OOE+OO I.63E-03 I.43E-OI 

4.00E+OI 4.02E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1. 32E-Ol 

5.00E+Ol 4. IOE-02 7. 93E-02 O.OOE+OO I.23E-03 1.22E-Ol 

6.00E+OI 4.19E-02 6. 98E-02 O.OOE+OO I.07E-03 I.l3E-OI 

7.00E+OI 4.27E-02 6.l4E-02 O.OOE+OO 9.3SE-04 I.OSE-Ol 

8.00E+OI 4. 34E-02 S.40E-02 O.OOE+OO 8.14E-04 9. 82E-02 

9.00E+OI 4.40E-02 4.75E-02 O.OOE+OO 7.09E-04 9.22E-02 

I.OOE+02 4. 46E-02 4.18E-02 O.OOE+OO 6.17E-04 B.70E-02 

2.00E+02 4.7SE-02 I.I5E-02 O.OOE+OO I.54E-04 S.92E-02 

3.00E+02 4. 82E-02 3. ISE-03 O.OOE+OO 3. 86E-OS 5.14E-02 

4.00E+02 4.B2E-02 B.5SE-04 O.OOE+OO 9.64E-06 4.9IE-02 

5.00E+02 4.8IE-02 2.3IE-04 O.OOE+OO 2.4IE-06 4. 84E-02 

6.00E+02 4. BOE-02 6.19E-05 O.OOE+OO 6.02E-07 4.8IE-02 

7.00E+02 4. 79E-02 1.65E-05 O.OOE+OO I.SIE-07 4.80E-02 

B.OOE+02 4.78E-02 4.40E-06 O.OOE+OO 3.77E-08 4.7BE-02 

9.00E+02 4.77E-02 1.I6E-06 O.OOE+OO O.OOE+OO 4. 77E-02 

I.OOE+03 4.77E-02 3.0BE-07 O.OOE+OO O.OOE+OO 4.77E-02 

2.00E+03 4. 68E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 68E-02 

3.00E+03 4. 59E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.59E-02 

4.00E+03 4.50E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.S0E-02 

S.OOE+03 4.42E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.42E-02 

7.00E+03 4. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4. 25E-02 

8.00E+03 4.17E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.l7E-02 

9.00E+03 4.09E-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.09E-02 

I.OOE+04 4.0IE-02 O.OOE+OO O.OOE+OO O.OOE+OO 4.0IE-02 

2.00E+04 3. 32E-02 O.OOE+OO O.OOE+OO O.OOE+OO 3. 32E-02 

B-335 
CLASS W AMAD = 1 MICRON BALFLIFE= 1.208+07 DAYS PROTACTINIUM 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6. 48E-03 8.l0E-06 

2.00E-Ol 1. 24E-02 1. 64E-04 

3.00E-Ol I. 69E-02 8.29E-04 

4.00E-Ol 2.03E-02 2. 42E-03 

5.00E-Ol 2. 29E-02 5. 28E-03 

6.00E-Ol 2. 49E-02 9.6lE-03 

7.00E-0l 2. 65E-02 1.SSE-02 

8.00E-Ol 2. 77E-02 2.30E-02 

9.00E-Ol 2. 86E-02 3. 19E-02 

1.00E+OO 2. 93E-02 2. 93E-02 4.2lE-02 4. 21E-02 

2.00E+OO 2. 69E-03 3.20E-02 1.35E-Ol 1. 77E-Ol 

3.00E+OO 8.7lE-04 3. 29E-02 1. 14E-Ol 2. 92E-Ol 

4.00E+OO 7. 18E-04 3. 36E-02 6. 64E-02 3. 58E-OI 

S.OOE+OO 6. 79E-04 3. 43E-02 3.4lE-02 3. 92E-Ol 

6.00E+OO 6. SlE-04 3.49E-02 1.7lE-02 4.09E-Ol 

7.00E+OO 6. 26E-04 3. 56E-02 8. 77E-03 4.l8E-Ol 

8.00E+OO 6.02E-04 3. 62E-02 4. 83E-03 4. 23E-Ol 

9.00E+OO 5.80E-04 3. 67E-02 2. 96E-03 4.26E-Ol 

1.OOE+Ol 5.60E-04 3.73E-02 2.07E-03 4. 28E-Ol 

2.00E+Ol 4.l1E-04 4.20E-02 1.08E-03 4.40E-Ol 

3.00E+Ol 3.2SE-04 4.S6E-02 9.43E-04 4.S0E-Ol 

4.00E+Ol 2.71E-04 4.8SE-02 8.2lE-04 4. 59E-Ol 

S.OOE+Ol 2.3SE-04 S.lOE-02 7.l5E-04 4. 67E-Ol 

7.00E+Ol l.86E-04 5.S2E-02 S.42E-04 4. 79E-Ol 

8.00E+Ol 1.67E-04 5. 69E-02 4.72E-04 4. 84E-Ol 

9.00E+Ol 1. SlE-04 S.8SE-02 4.11E-04 4. 88E-Ol 

1.OOE+02 1.37E-04 6.00E-02 3. S7E-04 4. 92E-Ol 

2.00E+02 4.9SE-OS 6. 85E-02 8. 94E-OS S.llE-Ol 

3.00E+02 1. 74E-OS 7.l6E-02 2.23E-05 S.16E-0l 

4.00E+02 6.3SE-06 7.27E-02 S.59E-06 S.17E-Ol 

S.OOE+02 2.67E-06 7.3lE-02 1.40E-06 S.18E-0l 

7.00E+02 1.09E-06 7. 34E-02 8. 73E-08 5.l8E-Ol 

8.00E+02 9.64E-07 7.3SE-02 2.l8E-08 S.18E-Ol 

9.00E+02 9. 25E-07 7. 36E-02 O.OOE+OO 5. 18E-Ol 

1.OOE+03 9.11E-07 7. 37E-02 O.OOE+OO S.18E-Ol 'j ." 2.00E+03 8. 88E-07 7. 46E-02 O.OOE+OO 5.l8E-Ol 

3.00E+03 8.72E-07 7.S5E-02 O.OOE+OO 5.l8E-Ol 

4.00E+03 8. 55E-07 7. 63E-02 O.OOE+OO S.18E-Ol 

5.00E+03 8. 39E-07 7.72E-02 O.OOE+OO 5.l8E-Ol 

7.00E+03 8.08E-07 7. 88E-02 O.OOE+OO S.18E-Ol 

8.00E+03 7. 92E-07 7.96E-02 O.OOE+OO S.l8E-Ol 

9.00E+03 7. 77E-07 8.04E-02 O.OOE+OO S.18E-Ol 

1.OOE+04 7. 63E-07 8.llE-02 O.OOE+OO 5.l7E-Ol 

2.00E+04 6.30E-07 8.80E-02 O.OOE+OO 5.17E-Ol 

B-336 
CLASS W AHAD = I" MICRON BALFLIFE- 5. 19E+01 DAYS URANIUM: 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 44E-02 2. 76E-01 2.3SE-Ol S.68E-02 6. 32E-Ol 

2.00E-Ol S.9lE-02 2.6SE-Ol 1. 97E-01 1. 04E-O 1 6.2SE-Ol 

3.00E-Ol S.S4E-02 2.S6E-01 1. 66E-01 1.42E-01 6. 19E-Ol 

4.00E-01 S.26E-02 2.47E-Ol 1. 39E-01 1. 73E-01 6.13E-01 

S.OOE-01 S.04E-02 2.40E-01 1.17E-0l 1. 99E-01 6.06E-Ol 

6.00E-01 4.87E-02 2. 33E-Ol 9. 86E-02 2.1SE-Ol S.98E-01 

7.00E-Ol 4. 72E-02 2. 27E-01 8. 29E-02 2. 33E-01 S.90E-01 

S.OOE-01 4.60E-02 2.21E-01 6. 97E-02 2. 43E-Ol S.80E-01 

9.00E-01 4. 49E-02 2. 16E-01 S.86E-02 2.S0E-Ol S.69E-01 

1.00E+OO 4. 39E-02 2.11E-01 4. 93E-02 2.S3E-01 S.S7E-01 

2.00E+OO 3.8SE-02 1.17E-01 8. 72E-03 1.93E-01 4. 17E-01 

3.00E+OO 3.SSE-02 1.60E-01 I.S4E-03 1.07E-01 3.04E-01 

4.00E+OO 3. 36E-02 I.S0E-01 2.72E-04 S.40E-02 2. 38E-01 

S.OOE+OO 3. 18E-02 1.4SE-01 4. 82E-OS 2. 69E-02 2.03E-Ol 

6.00E+OO 3.00E-02 1.41E-01 B.S1E-06 1.39E-02 1. SSE-01 

7.00E+OO 2.8SE-02 1. 38E-01 1.SlE-06 7.70E-03 1. 74E-01 

8.00E+OO 2.70E-02 1.36E-01 2.66E-07 4.17E-03 1. 68E-Ol 

9.00E+OO 2.S7E-02 1. 34E-01 4.70E-OB 3. 36E-03 1. 63E-01 

1.00E+01 2.4SE-02 1.32E-01 O.OOE+OO 2. 67E-03 1.S9E-01 

2.00EtOl 1. 66E-02 1. 16E-01 O.OOE+OO 1. 78E-03 1.3SE-Ol 

3.00E+01 1. 27E-02 1.02E-Ol O.OOE+OO I.SSE-03 1.17E-01 

4.00E+Ol 1.0SE-02 9.01E-02 O.OOE+OO 1.3SE-03 1.02E-01 

S.OOE+Ol 9.03E-03 7. 93E-02 O.OOE+OO 1.17E-03 B.9SE-02 

6.00E+Ol 7. 98E-03 6.9BE-02 O.OOE+OO 1.02E-03 7.BBE-02 

7.00E+Ol 7. 19E-03 6. 14E-02 O.OOE+OO B.90E-04 6.9SE-02 

8.00E+Ol 6.S9E-03 S.40E-02 O.OOE+OO 7.7SE-04 6. 14E-02 

9.00E+01 6. 11E-03 4.7SE-02 O.OOE+OO 6.7SE-04 S.43E-02 

l.OOE+02 S.73E-03 4.1BE-02 O.OOE+OO S.87E-04 4.BIE-02 

2.00E+02 4.06E-03 1.1SE-02 O.OOE+OO 1.47E-04 I.S7E-02 

3.00E+02 3.SBE-03 3.1SE-03 O.OOE+OO 3. 67E-OS 6.17E-03 

4.00E+02 3. 39E-03 B.SSE-04 O.OOE+OO 9. 18E-06 4. 26E-03 

S.OOE+02 3.30E-03 2. 31E-04 O.OOE+OO 2. 29E-06 3.S4E-03 

6.00E+02 3. 24E-03 6. 19E-OS O.OOE+OO S.74E-07 3.30E-03 

7.00E+02 3. 19E-03 1.6SE-OS O.OOE+OO l.43E-07 3. 21E-03 

B.OOE+02 3.l4E-03 4.40E ..... 06 O.OOE+OO 3.SBE-OB 3.1SE-03 

9.00E+02 3.10E-03 1. 16E-06 O.OOE+OO O.OOE+OO 3.10E-03 

1.00E+03 3.0SE-03 3.0BE-07 O.OOE+OO O.OOE+OO 3.0SE-03 

3.00E+03 2.2BE-03 O.OOE+OO O.OOE+OO O.OOE+OO 2.2BE-03 

S.OOE+03 1.71E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.7lE-03 

7.00E+03 1.29E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 29E-03 

9.00E+03 9.76E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9.76E-04 

1.00E+04 B.·49E-04 O.OOE+OO O.OOE+OO O.OOE+OO B.49E-04 

B-337 
CLASS W AHAD = 1 MICRON HALFLIFE= 5.79E+07 DAYS UBANIUH 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 6. 93E-03 8.06E-06 

2.00E-OI 1.37E-02 1. 62E-04 

3.00E-OI 1. 92E-02 8.17E-04 

4.00E-OI 2.40E-02 2. 38E-03 

5.00E-OI 2.80E-02 5.16E-03 

6.00E-OI 3.15E-02 9. 38E-03 

7.00E-OI 3.44E-02 1.5IE-02 

8.00E-OI 3.70E-02 2. 23E-02 . ; 9.00E-OI 3. 93E-02 3.09E-02 

I.OOE+OO 4.13E-02 4.13E-02 4.07E-02 4.07E-02 

2.00E+OO I.09E-02 5.2IE-02 1.29E-OI 1.70E-OI 

3.00E+OO 4.72E-03 5. 69E-02 1.08E-01 2. 78E-OI 

4.00E+OO 3. 22E-03 6.0IE-02 6. 28E-02 3.41E-OI 

5.00E+OO 2.69E-03 6. 28E-02 3. 23E-02 3. 73E-01 

6.00E+OO 2.40E-03 6. 52E-02 1.6IE-02 3. 89E-01 

7.00E+OO 2.19E-03 6. 74E-02 8.29E-03 3. 98E-01 

8.00E+OO 2.02E-03 6. 94E-02 4.57E-03 4.02E-OI 

9.00E+OO 1. 88E-03 7.13E-02 2.8IE-03 4.05E-OI 

I.OOE+OI 1.75E-03 7.30E-02 1.96E-03 4.07E-OI 

2.00E+OI 1.03E-03 8.60E-02 1.03E-03 4.19E-01 

3.00E+OI 7. 28E-04 9.44E-02 8.97E-04 4.28E-OI 

4.00E+01 5. 75E-04 I.OIE-Ol 7.8IE-04 4. 36E-OI 

S.OOE+01 4.80E-04 1.06E-OI 6.80E-04 4.44E-OI 

6.00E+OI 4.11E-04 1.IOE-Ol 5. 92E-04 4.S0E-OI 

7.00E+OI 3.S7E-04 1.14E-OI 5. 15E-04 4.5SE-01 

8.00E+OI 3. 12E-04 1. 18E-OI 4. 48E-04 4.60E-OI 

9.00E+OI 2. 75E-04 1.20E-OI 3.90E-04 4. 64E-OI 

I.OOE+02 2. 43E-04 1.23E-OI 3.40E-04 4. 68E-OI 

2.00E+02 7.49E-OS 1.37E-OI S.50E-OS 4.86E-01 

3.00E+02 2. 33E-OS 1.4IE-OI 2.12E-05 4.9IE-Ol 

4.00E+02 7.28E-06 1. 43E-0l 5. 31E-06 4.92E-01 

5.00E+02 2. 46E-06 1. 43E-OI 1. 33E-06 4. 92E-01 

6.00E+02 1.05E-06 1. 43E-0l 3. 32E-07 4. 92E-OI 

7.00E+02 6.3SE-07 1.44E-01 8.30E-OS 4.92E-Ol 

8.00E+02 S.13E-07 1.44E-Ol 2.07E-08 4.92E-OI 

9.00E+02 4. 74E-07 1.44E-Ol O.OOE+OO 4. 92E-OI 

1.00E+03 4.S8E-07 1.44E-0l O.OOE+OO 4. 92E-OI 

3.00E+03 3. 28E-07 1. 44E-Ol O.OOE+OO 4. 92E-OI 

5.00E+03 2. 42E-07 1.45E-OI O.OOE+OO 4.92E-Ol 

7.00E+03 1.8IE-07 1.45E-OI O.OOE+OO 4.92E-OI 

9.00E+03 1.36E-07 1.46E-Ol O.OOE+OO 4. 92E-01 

I.OOE+04 1. 18E-07 1.46E-Ol O.OOE+OO 4. 92E-Ol 

B-338 
CLASS W AMAD "" 1 KICRON BALFLIFE= 2. 57E+ 11 DAYS URANIUM 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.44E-02 2.76E-01 2.35E-0l 5.68E-02 6. 32E-01 

2.00E-01 5.91E-02 2. 65E-01 1. 97E-01 1.04E-01 6. 25E-01 

3.00E-01 5. 54E-02 2. 56E-01 1.66E-0l . 1.42E-0l 6.19E-0l 

4.00E-01 5. 26E-02 2. 47E-01 1. 39E-01 1.73E-Ol 6. 13E-Ol 

5.00E-Ol 5.04E-02 2.40E-Ol 1.17E-0l 1.99E-Ol 6.06E-Ol 

6.00E-01 4. 87E-02 2. 33E-01 9. 86E-02 2. 18E-01 5. 98E-01 

7.00E-01 4.72E-02 2. 27E-01 8.29E-02 2.33E-01 5.90E-01 

8.00E-01 4.60E-02 2.21E-Ol 6.97E-02 2. 43E-01 5.80E-Ol 

9.00E-Ol 4. 49E-02 2.16E-01 5.86E-02 2.50E-01 5.69E-Ol 

1.00E+OO 4. 39E-02 2.llE-Ol 4. 93E-02 2. 53E-01 5.57E-Ol 

2.00E+OO 3. 85E-02 1.77E-Ol 8.72E-03 1.93E-01 4. 17E-01 

3.00E+OO 3.S8E-02 1.60E-Ol 1. 54E-03 1.07E-01 3.04E-01 

4.00E+OO 3. 36E-02 1.S0E-OI 2. 72E-04 S.40E-02 2. 38E-01 

5.00E+OO 3.18E-02 I.45E-Ol 4. 82E-05 2. 69E-02 2.03E-01 

6.00E+OO 3.00E-02 1.4lE-Ol 8.S1E-06 1.39E-02 1.8SE-0l 

7.00E+OO 2.8SE-02 1. 38E-Ol l.SlE-06 7.70E-03 1. 74E-01 

8.00E+OO 2.70E-02 I.36E-01 2. 66E-07 4.77E-03 1. 68E-OI 

9.00E+OO 2.S7E-02 1. 34E-OI 4.70E-08 3. 36E-03 1. 63E-OI 

1.OOE+01 2.4SE-02 I.32E-OI O.OOE+OO 2. 67E-03 1.S9E-01 

2.00E+OI 1. 66E-02 I.I6E-Ol O.OOE+OO 1. 78E-03 1.3SE-01 

3.00E+01 1.27E-02 I.02E-01 O.OOE+OO 1.5SE-03 1. 17E-OI 

4.00E+OI 1.OSE-02 9.01E-02 O.OOE+OO 1.3SE-03 1.02E-01 

S.OOE+OI 9.03E-03 7. 93E-02 O.OOE+OO I.l7E-03 8.9SE-02 

6.00E+OI 7.98E-03 6. 98E-02 O.OOE+OO 1.02E-03 7. 88E-02 

7.00E+Ol 7. 19E-03 6. 14E-02 O.OOE+OO 8.90E-04 6.9SE-02 

8.00E+Ol 6.S9E-03 S.40E-02 O.OOE+OO 7.7SE-04 6. 14E-02 

9.00E+01 6. lIE-03 4.7SE-02 O.OOE+OO 6.7SE-04 S.43E-02 

I.OOE+02 S.73E-03 4. 18E-02 O.OOE+OO S.87E-04 4. 81E-02 

2.00E+02· 4.06E-03 I.ISE-02 O.OOE+OO 1.47E-04 1. S7E-02 

3.00E+02 3.S8E-03 3.1SE-03 O.OOE+OO 3. 67E-OS 6.77E-03 

4.00E+02 3. 39E-03 8.SSE-04 O.OOE+OO 9. 18E-06 4. 26E-03 

S.OOE+02 3.30E-03 2.31E-04 O.OOE+OO 2. 29E-06 3. S4E-03 

6.00E+02 3. 24E-03 6.19E-OS O.OOE+OO S.74E-07 3. 31E-03 

7.00E+02 3. 19E-03 1.6SE-OS O.OOE+OO 1.43E-07 3. 21E-03 

8.00E+02 3. 14E-03 4.40E-06 O.OOE+OO 3.S8E-OS 3.1SE-03 

9.00E+02 3.10E-03 1. 16E-06 O.OOE+OO O.OOE+OO 3.1OE-03 

: ~ "'. ~ ~. 1.00E+03 3.0SE-03 3.08E-07 O.OOE+OO O.OOE+OO 3.0SE-03 

3.00E+03 2. 28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 28E-03 

S.OOE+03 I.7lE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.7lE-03 

7.00E+03 1. 29E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 29E-03 

9.00E+03 9. 76E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 76E-04 

1.00E+04 8. 49E-04 O.OOE+OO O.OOE+OO O.OOE+OO 8. 49E-04 

B-339 
CLASS W AMAD = 1 MICRON HALFLIFE= 2. 57E+ 11 DAYS URANIUM 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 6. 93E-03 S.06E-06 

2.00E-Ol 1.37E-02 1.62E-04 

3.00E-Ol 1.92E-02 S.17E-04 

4.00E-Ol 2.40E-02 2. 38E-03 

S.OOE-Ol 2.80E-02 S.16E-03 

6.00E-Ol 3.lSE-02 9.3SE-03 

7.00E-Ol 3.44E-02 1.SlE-02 

S.OOE-Ol 3.70E-02 2. 23E-02 

9.00E-Ol 3. 93E-02 3.09E-02 

1.OOE+OO 4.l3E-02 4.l3E-02 4.07E-02 4.07E-02 

2.00E+OO 1.09E-02 S.2lE-02 1.29E-0l 1.70E-Ol 

3.00E+OO 4.72E-03 S.69E-02 1.OSE-Ol 2.7SE-Ol 

4.00E+OO 3. 22E-03 6.0lE-02 6.2SE-02 3.4lE-Ol 

S.OOE+OO 2. 69E-03 6.2SE-02 3. 23E-02 3. 73E-Ol 

6.00E+OO 2.40E-03 6.S2E-02 1.6lE-02 3.S9E-Ol 

7.00E+OO 2.l9E-03 6. 74E-02 8. 29E-03 3. 98E-O! 

S.OOE+OO 2.02E-03 6. 94E-02 4.S7E-03 4.02E-Ol 

9.00E+OO 1.SSE-03 7.l3E-02 2.SlE-03 4.0SE-Ol 

1.OOE+Ol 1.7SE-03 7.30E-02 1.96E-03 4.07E-Ol 

2.00'E+Ol 1.03E-03 S.60E-02 1.03E-03 4.l9E-Ol 

3.00E+Ol 7.2SE-04 9. 44E-02 S.97E-04 4.2SE-Ol 

4.00E+Ol S.7SE-04 1.OlE-Ol 7.SlE-04 4.36E-Ol 

S.OOE+Ol 4.S0E-04 1.06E-Ol 6. SOE-04 4.44E-Ol 

6.00E+Ol 4.llE-04 1.lOE-Ol S.92E-04 4.S0E-Ol 

7.00E+Ol 3.S7E-04 1.14E-OI S.lSE-04 4.SSE-Ol 

S.OOE+Ol 3.l2E-04 1.lSE-Ol 4.4SE-04 4.60E-Ol 

9.00E+Ol 2.7SE-04 1.20E-Ol 3.90E-04 4. 64E-Ol 

I.OOE+02 2. 43E-04 1.23E-Ol 3.40E-04 4.6SE-Ol 

2.00E+02 7. 49E-OS 1.37E-Ol S.SOE-OS 4.S6E-Ol 

3.00E+02 2. 33E-OS 1.4lE-Ol 2.l2E-OS 4.91E-Ol 

4.00E+02 7.2SE-06 1.43E-OI S.3lE-06 4.92E-Ol 

S.OOE+02 2. 46E-06 1.43E-OI 1. 33E-06 4.92E-Ol 

6.00E+02 1.OSE-06 1.43E-OI 3.32E-07 4. 92E-Ol 

7.00E+02 6.3SE-07 1.44E-OI S.30E-OS 4. 92E-Ol 

S.OOE+02 S.13E-07 1.44E-Ol 2.07E-OS 4.92E-Ol 

9.00E+02 4. 74E-07 1.44E-Ol O.OOE+OO 4.92E-Ol '.' 1.OOE+03 4.SSE-07 1.44E-OI O.OOE+OO 4.92E-Ol ; .. , 

3.00E+03 3.2SE-07 1.44E-Ol O.OOE+OO 4. 92E-OI 

S.OOE+03 2. 42E-07 1.4SE-Ol O.OOE+OO 4. 92E-Ol 

7.00E+03 1.SlE-07 1.4SE-OI O.OOE+OO 4. 92E-OI 

9.00E+03 I. 36E-07 1.46E-Ol O.OOE+OO 4.92E-Ol 

1.OOE+04 1.lSE-07 1.46E-Ol O.OOE+OO 4. 92E-Ol 

B-340 
CLASS W AHAD ... 1 MICRON BALFLIJ!E= 1.16E+12 DAYS URANIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 6. 44E-02 2.76E-Ol 2.3SE-0l S.6BE-02 6.32E-Ol 

2.00E-Ol S.9lE-02 2.6SE-Ol 1. 97E-Ol 1.04E-Ol 6.2SE-Ol 

3.00E-Ol S. S4E-02 2. S6E-Ol 1.66E-Ol 1.42E-OI 6.l9E-Ol 

4.00E-Ol S.26E-02 2. 47E-Ol 1. 39E-OI 1. 73E-OI 6.13E-OI 

S.OOE-Ol S.04E-02 2.40E-Ol 1. 17E-Ol 1.99E-Ol 6.06E-OI 

6.00E-Ol 4.B7E-02 2. 33E-OI 9.B6E-02 2.IBE-Ol S.9BE-Ol 

7.00E-Ol 4. 72E-02 2.27E-OI B.29E-02 2.33E-Ol S.90E-OI 

B.OOE-Ol 4.60E-02 2.21E-OI 6. 97E-02 2. 43E-Ol S.BOE-OI 

9.00E-OI 4.49E-02 2. 16E-Ol S.B6E-02 2. SOE-OI S.69E-OI 

I.OOE+OO 4. 39E-02 2.llE-OI 4.93E-02 2.S3E-Ol S.S7E-OI 

2.00E+OO 3. BSE-02 I.77E-0l B.72E-03 1. 93E-Ol 4.l7E-OI 

3 .. 00E+OO 3.SBE-02 I.60E-OI 1. S4E-03 I.07E-Ol 3.04E-OI 

4.00E+OO 3.36E-02 1. SOE-OI 2. 72E-04 S.40E-02 2.3BE-OI 

S.OOE+OO 3.IBE-02 I.4SE-Ol 4.B2E-OS 2. 69E-02 2.03E-OI 

6.00E+OO 3.00E-02 1.4IE-OI B.SIE-06 I.39E-02 1. BSE-OI 

7.00E+OO 2. BSE-02 1.3BE-OI I.SIE-06 7.70E-03 1. 74E-OI 

B.OOE+OO 2.70E-02 I.36E-OI 2. 66E-07 4.77E-03 1.6BE-OI 

9.00E+OO 2.S7E-02 1. 34E-Ol 4.70E-OB 3. 36E-03 1. 63E-OI 

I.OOE+OI 2.4SE-02 1.32E-Ol O.OOE+OO 2. 67E-03 1. S9E-OI 

2.00E+OI 1. 66E-02 I.I6E-Ol O.OOE+OO I.7BE-03 I.3SE-OI 

3.00E+Ol I.27E-02 1.02E-OI O.OOE+OO 1. SSE-03 1.17E-0l 

4.0CE+OI I.OSE-02 9.0lE-02 O.OOE+OO I.3SE-03 I.02E-OI 

S.OOE+OI 9.03E-03 7. 93E-02 O.OOE+OO 1.17E-03 B.9SE-02 

6.00E+OI 7.9BE-03 6.9BE-02 O.OOE+OO I.02E-03 7.BBE-02 

7.00E+OI 7.19E-03 6.14E-02 O.OOE+OO 8.90E-04 6.9SE-02 

B.OOE+Ol 6.S9E-03 S.40E-02 O.OOE+OO 7.7SE-04 6. 14E-02 

9.00E+OI 6.IIE-03 4.7SE-02 O.OOE+OO 6.7SE-04 S.43E-02 

I.OOE+02 S.73E-03 4.1BE-02 O.OOE+OO S.B7E-04 4.BIE-02 

2.00E+02 4.06E-03 1. ISE-02 O.OOE+OO I.47E-04 I.S7E-02 

3.00E+02 3.SBE-03 3. ISE-03 O.OOE+OO 3. 67E-OS 6.77E-03 

4.00E+02 3. 39E-03 B. SSE-04 O.OOE+OO 9.1BE-06 4. 26E-03 

S.OOE+02 3.30E-03 2.3lE-04 O.OOE+OO 2. 29E-06 3. S4E-03 

6.00E+02 3. 24E-03 6.19E-OS O.OOE+OO S.74E-07 3.3IE-03 

7.00E+02 3. 19E-03 1.6SE-OS O.OOE+OO I.43E-07 3.2IE-03 

B.OOE+02 3.l4E-03 4.40E-06 O.OOE+OO 3. S8E-OB 3. ISE-03 

9.00E+02 3.1OE-03 I.I6E-06 O.OOE+OO O.OOE+OO 3. IOE-03 

I.OOE+03 3.0SE-03 3.08E-07 O.OOE+OO O.OOE+OO 3.0SE-03 

3.00E+03 2.28E-03 O.OOE+OO O.OOE+OO O.OOE+OO 2. 28E-03 

S.OOE+03 I.7lE-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.7lE-03 

7.00E+03 I.29E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1. 29E-03 

9.00E+03 9.76E-04 O.OOE+OO O.OOE+OO O.OOE+OO 9. 76E-04 

1.00E+04 B.49E-04 O.OOE+OO O.OOE+OO O.OOE+OO 8. 49E-04 

B-341 
CLASS W AHA» == 1 MICRON BALFLIFE= 1.16E+12 DAYS URANIUK 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.00E-Ol 6.93E-03 8.06E-06 

2.00E-Ol 1.37E-02 1. 62E-04 

3.00E-Ol 1.92E-02 8. 17E-04 

4.00E-Ol 2.40E-02 2. 38E-03 

5.00E-Ol 2.80E-02 5. 16E-03 

6.00E-Ol 3. 15E-02 9. 38E-03 

7.00E-Ol 3. 44E-02 1.51E-02 

8.00E-Ol 3.70E-02 2. 23E-02 

9.00E-Ol 3. 93E-02 3.09E-02 

1.00E+00 4. 13E-02 4.13E-02 4.07E-02 4.07E-02 

2.00E+00 1.09E-02 5. 21E-02 1.29E-Ol 1.70E-Ol 

3.00E+00 4. 72E-03 5. 69E-02 1.08E-Ol 2. 78E-Ol 

4.00E+00 3. 22E-03 6.01E-02 6. 28E-02 3.41E-Ol 

5.00E+00 2.69E-03 6. 28E-02 3. 23E-02 3. 73E-Ol 

6.00E+00 2.40E-03 6. 52E-02 1. 61E-02 3.89E-Ol 

7.00E+00 2. 19E-03 6. 74E-02 8. 29E-03 3. 98E-Ol 

8.00E+00 2.02E-03 6. 94E-02 4.57E-03 4.02E-Ol 

9.00E+00 1. 88E-03 7.13E-02 2.81E-03 4.05E-Ol 

1.00E+Ol 1.75E-03 7.30E-02 1. 96E-03 4.07E-01 

2.00E+Ol 1.03E-03 8.60E-02 1.03E-03 4. 19E-01 

3.00E+Ol 7.28E-04 9. 44E-02 8. 97E-04 4. 28E-Ol 

4.00E+01 5. 75E-04 1.01E-01 7.81E-04 4. 36E-Ol 

5.00E+01 4.80E-04 1.06E-Ol 6.80E-04 4.44E-Ol 

6.00E+01 4.11E-04 1.lOE-01 5. 92E-04 4.50E-01 

7.00E+01 3. 57E-04 1. 14E-Ol 5. 15E-04 4. 55E-01 

8.00E+01 3. 12E-04 1.1BE-01 4.48E-04 4.60E-Ol 

9.00E+Ol 2. 75E-04 1.20E-Ol 3.90E-04 4.64E-01 

1.00E+02 2.43E-04 1.23E-Ol 3.40E-04 4.68E-Ol 

2.00E+02 7.49E-05 1.37E-01 8.50E-05 4.86E-01 

3.00E+02 2. 33E-05 1.41E-Ol 2. 12E-05 4.91E-01 

4.00E+02 7. 28E-06 1.43E-Ol 5.31E-06 4.92E-Ol 

5.00E+02 2. 46E-06 1.43E-01 1.33E-06 4. 92E-Ol 

6.00E+02 1.05E-06 1.43E-01 3. 32E-07 4. 92E-.ol 

7.00E+02 6.35E-07 1. 44E-Ol 8.30E-08 4.92E-01 

8.00E+02 5. 13E-07 1.44E-Ol 2.07E-08 4. 92E-Ol 

9.00E+02 4. 74E-07 1.44E-Ol O.OOE+OO 4.92E-Ol 

1.00E+03 4.58E-07 1.44E-Ol O.OOE+OO 4.92E-01 

3.00E+03 3.28E-07 1. 44E-01 O.OOE+OO 4. 92E-01 

5.00E+03 2. 42E-07 1.45E-01 O.OOE+OO 4. 92E-Ol 

7.00£+03 1.81E-07 1.45E-01 O.OOE+OO 4. 92E-Ol 

9.00E+03 1.36E-07 1.46E-Ol O.OOE+OO 4.92E-Ol 

1.00E+04 1.18E-07 1.46E-01 O.OOE+OO 4.92E-01 

B-342 
CLASS W AMAD = 1 MICRON HALFLIFE= 7. 81E+08 DAYS NEPTUNIUM 237 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 6. 96E-02 2. 76E-Ol 2. 35E-Ol 5.7lE-02 6.3SE-Ol 

2.00E-Ol 6. 86E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 36E-Ol 

3.00E-Ol 6.79E-02 2. 56E-Ol 1.66E-Ol 1.45E-OI 6. 34E-Ol 

4.00E-Ol 6. 76E-02 2.47E-Ol 1. 39E-Ol 1.78E-OI 6. 32E-Ol 

5.00E-Ol 6. 74E-02 2.40E-Ol 1.17E-Ol 2.04E-Ol 6.29E-Ol 

6.00E-Ol 6. 73E-02 2. 33E-Ol 9. 86E-02 2. 25E-Ol 6.24E-Ol 

7.00E-Ol 6. 73E-02 2. 27E-Ol 8.29E-02 2.4lE-Ol 6.l8E-Ol 

S.OOE-Ol 6. 73E-02 2.2lE-Ol 6. 97E-02 2. 52E-Ol 6.l0E-Ol 

9.00E-0l 6. 73E-02 2.16E-Ol 5. 86E-02 2.59E-Ol 6.0lE-Ol 

1.OOE+OO 6. 74E-02 2. llE-Ol 4. 93E-02 2. 63E-Ol 5.90E-Ol 

2.00E+OO 6.83E-02 1.77E-Ol S.72E-03 2.0lE-Ol 4. 56E-Ol 

3.00E+OO 6.89E-02 1.60E-Ol 1. 54E-03 1.12E-Ol 3. 42E-Ol 

4.00E+OO 6.95E-02 1.50E-Ol 2.72E-04 5.66E-02 2. 77E-Ol 

5.00E+OO 7.00E-02 1. 45E-Ol 4.S2E-05 2.S2E-02 2. 43E-Ol 

6.00E+OO 7.0SE-02 1. 41E-Ol 8.5IE-06 1.45E-02 2.26E-Ol 

7.00E+OO 7.09E-02 1.3SE-Ol 1.5lE-06 S.05E-03 2.l7E-Ol 

8.00E+OO 7.l4E-02 1.36E-Ol 2.66E-07 4.99E-03 2.l2E-Ol 

9.00E+OO 7.l8E-02 1. 34E-Ol 4.70E-08 3.5lE-03 2.09E-Ol 

1.OOE+Ol 7.22E-02 1. 32E-Ol O.OOE+OO 2.79E-03 2.07E-Ol 

2.00E+Ol 7. 64E-02 1.16E-OI O.OOE+OO 1. 85E-03 1. 94E-Ol 

3.00E+Ol 8.0lE-02 1.02E-Ol O.OOE+OO 1.6lE-03 1.S4E-01 

4.00E+Ol 8. 35E-02 9.0IE-02 O.OOE+OO 1.40E-03 1.75E-Ol 

S.OOE+Ol 8.66E-02 7. 93E-02 O.OOE+OO 1. 22E-03 1. 67E-Ol 

6.00E+Ol S.93E-02 6. 98E-02 O.OOE+OO 1.06E-03 1.60E-Ol 

7.00E+0l 9.lSE-02 6.l4E-02 O.OOE+OO 9.27E-04 I.S4E-Ol 

S.OOE+OI 9.40E-02 5.40E-02 O.OOE+OO S.07E-04 1.49E-Ol 

9.00E+Ol 9.60E-02 4. 75E-02 O.OOE+OO 7.02E-04 1. 44E-OI 

1.OOE+02 9.7SE-02 4.l8E-02 O.OOE+OO 6. 12E-04 1.40E-Ol 

2.00E+02 1.08E-Ol 1.15E-02 O.OOE+OO 1.53E-04 1.20E-Ol 

3.00E+02 1. llE-Ol 3.l5E-03 O.OOE+OO 3.S2E-05 1. 14E-Ol 

4.00E+02 1.12E-Ol S.55E-04 O.OOE+OO 9.56E-06 1.l3E-Ol 

S.OOE+02 1. 12E-Ol 2. 31E-04 O.OOE+OO 2. 39E-06 1.12E-Ol 

6.00E+02 1.11E-Ol 6. 19E-05 O.OOE+OO 5.97E-07 1. llE-Ol 

7.00E+02 1. llE-Ol 1. 65E-05 O.OOE+OO 1. 49E-07 1. liE-Ol 

8.00E+02 1.11E-0l 4.40E-06 O.OOE+OO 3.73E-OS 1.liE-0l 

9.00E+02 1.1OE-Ol l.l6E-06 O.OOE+OO O.OOE+OO 1.lOE-OI 

l.OOE+03 1.1OE-Ol 3.0SE-07 O.OOE+OO O.OOE+OO 1.lOE-Ol 

3.00E+03 1.03E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-Ol 

5.00E+03 9. 64E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 64E-02 

7.00E+03 9.05E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.05E-02 

9.00E+03 S.49E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 49E-02 

1.OOE+04 8. 23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 23E-02 

B-343 
CLASS W AMAD == 1 KleR.ON BALFLIFE== 7.81E+08 DAYS NEPTUNIUM 237 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATE 

DAYS URINE URINE FECES FECES 

I.OOE-Ol 7.4SE-04 7.S3E-04 

2.00E-Ol I.42E-03 I.S9E-03 

3.00E-OI I.94E-03 2.77E-03 

4.00E-OI 2. 34E-03 4. 75E-03 

5.00E-OI 2.6SE-03 7.91E-03 

6.00E-OI 2. 89E-03 1. 25E-02 

7.00E-Ol 3.07E-03 1.8SE-02 

8.00E-Ol 3. 22E-03 2.61E-02 

9.00E-OI 3. 33E-03 3.S0E-02 

I.OOE+OO 3. 42E-03 3.42E-03 4.S3E-02 4.S3E-02 

2.00E+OO 3.20E-04 3. 74E-03 I.34E-OI 1. BOE-Ol 

3.00E+OO 6.S4E-OS 3.80E-03 1.l3E-Ol 2. 93E-Ol 

4.00E+OO 3. 62E-OS 3. 84E-03 6.S8E-02 3. 59E-OI 

S.OOE+OO 3.02E-OS 3. 87E-03 3.3BE-02 3. 92E-OI 

6.00E+OO 2. BOE-OS 3.90E-03 1.69E-02 4.09E-Ol 

7.00E+OO 2.70E-OS 3. 92E-03 8.7IE-03 4.18E-Ol 

8.00E+OO 2. 63E-05 3. 95E-03 4. BIE-03 4. 23E-Ol 

9.00E+OO 2.S9E-05 3. 98E-03 2. 96E-03 4.26E-Ol 

I.OOE+Ol 2. 56E-05 4.00E-03 2.07E-03 4.28E-Ol 

2.00E+Ol 2. 33E-05 4. 24E-03 .I.lOE-03 4.40E-OI 

3.00E+Ol 2.13E-OS 4.47E-03 9. S6E-04 4.S1E-OI 

4.00E+OI 1.9SE-05 4. 67E-03 B.33E-04 4.S9E-OI 

S.OOE+Ol I.7BE-OS 4. 86E-03 7.26E-04 4.67E-Ol 

6.00E+OI 1.63E-05 S.03E-03 6. 33E-04 4. 74E-OI 

7.00E+Ol I.4BE-OS S.18E-03 S.52E-04 4.80E-Ol 

8.00E+Ol 1. 36E-05 S.32E-03 4.81E-04 4.8SE-Ol 

9.00E+Ol 1.24E-05 S.45E-03 4.19E-04 4.B9E-Ol 

1.OOE+02 1.l3E-OS S.57E-03 3. 66E-04 4. 93E-Ol 

2.00E+02 4. 97E-06 6.33E-03 9.3SE-05 5.l3E-Ol 

3.00E+02 2. 82E-06 6. 69E-03 2.S0E-OS S.lBE-Ol 

4.00E+02 2.14E-06 6. 94E-03 7. 68E-06 S.20E-Ol 

S.OOE+02 1. 93E-06 7.14E-03 3. 32E-06 5.20E-Ol 

6.00E+02 1.87E-06 7.33E-03 2.2lE-06 S.20E-Ol 

7.00E+02 1. 84E-06 7.S1E-03 1. 93E-06 S.2IE-Ol 

8.00E+02 1. 83E-06 7.70E-03 1.8SE-06 S.21E-0l 

9.00E+02 1.82E-06 7.B8E-03 1. 83E-06 S.21E-Ol 

1.OOE+03 1.8IE-06 B.06E-03 1. 82E-06 S.2lE-Ol 

3.00E+03 1.6BE-06 1.16E-02 1. 68E-06 S.2SE-Ol 

S.OOE+03 1.SSE-06 l.48E-02 1.S5E-06 5. 28E-Ol 

7.00E+03 l.44E-06 l.7BE-02 1. 44E-06 5.3lE-Ol 

9.00E+03 1. 33E-06 2.0SE-02 I.33E-06 5.34E-Ol 

l.OOE+04 l.2BE-06 2.l9E-02 1.2BE-06 5. 35E-Ol 

B-344 
CLASS W .AHAD = 1 MICR.ON BALFLlFE= 3.20E+04 DAYS PLUTONIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------~--------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 7.09E-02 2.76E-01 2.3SE-01 S.72E-02 6. 39E-01 

2.00E-01 7.10E-02 2.6SE-01 1.97E-01 I.OSE-OI 6. 39E-01 

3.00E-01 7.lOE-02 2.S6E-01 1. 66E-01 1.46E-Ol 6.38E-01 

4.00E-01 7.10E-02 2. 47E-01 1. 39E-Ol 1. 79E-01 6.36E-Ol 

S.OOE-01 7.10E-02 2.40E-01 1.17E-Ol 2.06E-Ol 6.34E-Ol 

6.00E-Ol 7.lOE-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6. 29E-Ol 

7.00E-Ol 7.lOE-02 2. 27E-Ol 8.29E-02 2.43E-Ol 6. 23E-Ol 

8.00E-Ol 7.l0E-02 2.2lE-Ol 6. 97E-02 2.S4E-Ol 6.l6E-Ol 

9.00E-Ol 7.l0E-02 2.l6E-Ol S.86E-02 2.6lE-Ol 6.07E-Ol 

1.OOE+OO 7.lOE-02 2.llE-Ol 4. 93E-02 2.6SE-Ol S.96E-Ol 

2.00E+OO 7.l2E-02 I.77E-Ol 8. 72E-03 2.04E-Ol 4.6lE-0l 

3.00E+OO 7.lSE-02 I.60E-Ol I.S4E-03 1.13E-Ol 3. 46E-Ol 

4.00E+OO 7.I9E-02 I.SOE-Ol 2.72E-04 S.72E-02 2.80E-Ol 

S.OOE+OO 7. 23E-02 1.4SE-Ol 4. 82E-OS 2.8SE-02 2.4SE-Ol 

6.00E+OO 7. 27E-02 1.4lE-Ol 8. SlE-06 1. 47E-02 2. 28E-Ol 

7.00E+OO 7.3lE-02 1. 38E-Ol 1. SOE-06 8.l4E-03 2.l9E-Ol 

8.00E+OO 7.3SE-02 1.36E-Ol 2.66E-07 S.04E-03 2.l4E-0l 

9.00E+OO 7.40E-02 1. 34E-Ol 4. 70E-08 3.SSE-03 2.11E-bl 

1.00E+01 7. 44E-02 1. 32E-01 O.OOE+OO 2. 82E-03 2.09E-Ol 

2.00E+Ol 7.8SE-02 1. 16E-01 O.OOE+OO 1.87E-03 1. 96E-Ol 

3.00E+Ol 8. 22E-02 1.02E-Ol O.OOE+OO 1.63E-03 1.86E-Ol 

4.00E+Ol 8.S6E-02 9.00E-02 O.OOE+OO 1. 42E-03 1. 77E-Ol 

S.OOE+Ol 8. 86E-02 7.92E-02 O.OOE+OO 1.23E-03 1.69E-Ol 

6.00E+01 9.l4E-02 6. 97E-02 O.OOE+OO 1.07E-03 1. 62E-Ol 

7.00E+01 9.38E-02 6. 13E-02 O.OOE+OO 9.3SE-04 1.S6E-Ol 

8.00E+Ol 9.6lE-02 S.39E-02 O.OOE+OO 8.13E-04 1.SlE-Ol 

9.00E+Ol 9.80E-02 4. 74E-02 O.OOE+OO 7.08E-04 1. 46E-Ol 

1.OOE+02 9. 98E-02 4.l7E-02 O.OOE+OO 6.l6E-04 1. 42E-Ol 

2.00E+02 1.09E-Ol 1.lSE-02 O.OOE+OO 1.S4E-04 1.2lE-Ol 

3.00E+02 1.llE-Ol 3.13E-03 O.OOE+OO 3~83E-OS 1.lSE-Ol 

4.00E+02 1.llE-0l 8. 48E-04 O.OOE+OO 9.s7E-06 1.12E-Ol 

s.OOE+02 1.11E-Ol 2. 28E-04 O.OOE+OO 2. 39E-06 1.llE-Ol 

6.00E+02 1.lOE-0l 6. lIE-OS O.OOE+OO s.9sE-07 1.lOE-Ol 

7.00E+02 1.09E-OI 1.63E-OS O.OOE+OO 1. 48E-07 1.09E-01 

8.00E+02 1.09E-01 4. 32E-06 O.OOE+OO 3.70E-08 1.09E-Ol 

9.00E+02 1.08E-01 1. 14E-06 O.OOE+OO O.OOE+OO 1.08E-Ol 

1.OOE+03 1.07E-01 3.01E-07 O.OOE+OO O.OOE+OO 1.07E-01 : ",'". 3.00E+03 9.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.71E-02 

s.OOE+03 8. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.78E-02 

7.00E+03 7.9sE-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.95E-02 

9.00E+03 7.l9E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7.19E-02 

1.00E+04 6. 84E-02 O.OOE+OO O.OOE+OO O.OOE+OO 6. 84E-02 

B-34s 
CLASS W AMAD = 1 MICRON BALFLlFE= 3.20E+o4 DAYS PLUTONIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.0SE-OS 3.4lE-OS 

2.00E-Ol 6.46E-OS 2.l9E-04 

3.00E-Ol 9. 69E-OS 9.llE-04 

4.00E-Ol 1. 28E-04 2.S3E-03 

S.OOE-Ol 1. S7E-04 S.4lE-03 

6.00E-Ol 1.'8SE-04 9. 77E-03 

7.00E-Ol 2.llE-04 1.S7E-02 

8.00E-Ol 2. 36E-04 2. 32E-02 

9.00E-Ol 2.60E-04 3.2lE-02 

1.OOE+OO 2. 83E-04 2. 83E-04 4. 24E-02 4. 24E-02 

2.00E+OO 1.76E-04 4.S9E-04 1. 36E-Ol 1.78E-0l 

3.00E+OO 1.12E-04 S.71E-04 1.14E-Ol 2. 92E-Ol 

4.00E+OO 7.S3E-OS 6. 47E-04 6.6SE-02 3.S9E-Ol 

S.OOE+OO S.39E-OS 7.0lE-04 3. 42E-02 3. 93E-Ol 

6.00E+OO 4.lSE-OS 7.42E-04 1.7lE-02 4.l0E-Ol 

7.00E+OO 3. 42E-OS 7.76E-04 8.8lE-03 4.l9E-Ol 

8.00E+OO 2. 98E-OS 8.06E-04 4.86E-03 4. 24E-Ol 

9.00E+OO 2.71E-OS 8. 33E-04 2. 99E-03 4. 27E-Ol 

1.00E+Ol 2.S4E-OS 8. S8E-04 2.09E-03 4. 29E-Ol 

2.00E+Ol 2.0lE-OS 1.08E-03 1.lOE-03 4.41E-Ol 

3.00E+Ol 1.76E-OS 1.26E-03 9. S9E-04 4. SlE-Ol 

4.00E+Ol 1.S8E-OS 1.43E-03 8.3SE-04 4.60E-Ol 

5.00E+Ol 1.4SE-OS 1. 58E-03 7.27E-04 4.68E-Ol 

6.00E+Ol 1. 36E-05 1. 72E-03 6. 34E-04 4.74E-Ol 

7.00E+Ol 1. 28E-OS 1. 85E-03 S. S2E-04 4.80E-Ol 

8.00E+Ol 1. 22E-05 1. 97E-03 4. 82E-04 4. 85E-Ol 

9.00E+Ol 1.16E-05 2.09E-03 4.20E-04 4.90E-Ol 

1.OOE+02 1.llE-05 2.20E-03 3. 66E-04 4. 93E-OI 

2.00E+02 7.8SE-06 3.l3E-03 9.S7E-05 S.12E-Ol 

3.00E+02 S.80E-06 3.80E-03 2.72E-05 5.17E-Ol 

4.00E+02 4. 45E-06 4. 29E-OJ 9.34E-06 S.l7E-Ol 

S.OOE+02 3. 56E-06 4. 68E-03 4.4lE-06 S.17E-Ol 

6.00E+02 2. 95E-06 4. 99E-03 2. 86E-06 S.16E-0l 

7.00E+02 2.S4E-06 S.26E-OJ 2. 25E-06 S.lSE-Ol 

8.00E+02 2. 25E-06 5. 48E-03 1. 94E-06 5.l4E-OI 

9.00E+02 2.06E-06 5. 69E-03 1. 76E-06 S.13E-Ol 

1.OOE+03 1. 92E-06 S.87E-03 1.64E-06 S.12E-Ol 

3.00E+03 1. 49E-06 8. 75E-OJ 1. 27E-06 4. 93E-Ol 

5.00E+03 1.3SE-06 1.12E-02 1.lSE-06 4.7SE-OI 

7.00E+03 1. 22E-06 1. 32E-02 1.04E-06 4.S7E-Ol 

9.00E+03 1.lOE-06 1.49E-02 9.39E-07 4. 39E-Ol 

1.OOE+04 1.OSE-06 1.S6E-02 8. 93E-07 4.31E-Ol 

B-346 
CLASS W AKAD = 1 MICRON HALFLIFE= 8.78E+06 DAYS PLUTONIUH 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------~-----------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 7.09E-02 2.76E-Ol 2.3SE-0l S.72E-02 6.39E-Ol 

2.00E-Ol 7.l0E-02 2.6SE-Ol 1. 97E-Ol 1.OSE-Ol 6. 39E-Ol 

3.00E-Ol 7.l0E-02 2. S6E-Ol 1. 66E-0l 1.46E-Ol 6.38E-Ol 

4.00E-Ol 7.10E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.36E-Ol 

S.OOE-Ol 7.10E-02 2.40E-Ol 1.17E-Ol 2.06E-Ol 6. 34E-Ol 

6.00E-Ol 7.10E-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6. 29E-Ol 

7.00E-Ol 7.l0E-02 2.27E-0l 8. 29E-02 2. 43E-Ol 6.23E-Ol 

8.00E-Ol 7.10E-02 2.2lE-Ol 6. 97E-02 2.S4E-Ol 6. 1 6E-O 1 

9.00E-Ol 7.10E-02 2.l6E-0l S.86E-02 2.6lE-0l 6.07E-Ol 

1.OOE+OO 7.lOE-02 2.llE-Ol 4. 93E-02 2. 65E-Ol S.96E-Ol 

2.00E+OO 7.l2E-02 1.77E-Ol 8.72E-03 2.04E-Ol 4.6lE-0l 

3.00E+OO 7.lSE-02 1.60E-Ol 1.S4E-03 1.l3E-Ol 3. 46E-Ol 

4.00E+OO 7.l9E-02 1. SOE-Ol 2. 72E-04 S.72E-02 2.80E-Ol 

5.00E+OO 7. 23E-02 1. 45E-Ol 4. 82E-OS 2. 85E-02 2.4SE-Ol 

6.00E+OO 7.27E-02 1.4lE-Ol 8.5lE-O€> 1.47E-02 2. 28E-Ol 

7.00E+OO 7.31E-02 1. 38E-Ol 1.5lE-06 8.l4E-03 2.l9E-Ol 

8.00E+OO 7.3SE-02 1. 36E-Ol 2. 66E-07 5.04E-03 2.l4E-0l 

9.00E+OO 7.40E-02 1. 34E-Ol 4.70E-08 3. 55E-03 2.llE;..Ol 

1.OOE+Ol 7. 44E-02 1.32E-Ol O.OOE+OO 2. 82E-03 2.09E-Ol 

2.00E+Ol 7. 85E-02 1.16E-Ol O.OOE+OO 1.87E-03 1. 97E-Ol 

3.00E+Ol 8. 22E-02 1.02E-0l O.OOE+OO 1.63E-03 1. 86E-Ol 

4.00E+Ol 8. 56E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1.77E-Ol 

S.OOE+Ol 8.87E-02 7.93E-02 O.OOE+OO 1.24E-03 1.69E-Ol 

6.00E+Ol 9.lSE-02 6. 98E-02 O.OOE+OO 1.08E-03 1.62E-Ol 

7.00E+Ol 9.40E-02 6.l4E-02 O.OOE+OO 9.36E-04 1. S6E-Ol 

8.00E+Ol 9.62E-02 S.40E-02 O.OOE+OO 8.l5E-04 1.SlE-Ol 

9.00E+Ol 9. 82E-02 4.7SE-02 O.OOE+OO 7.09E-04 1.46E-Ol 

1.OOE+02 1.OOE-Ol 4.18E-02 O.OOE+OO 6.l8E-04 1. 42E-Ol 

2.00E+02 1.lOE-0l 1.lSE-02 O.OOE+OO 1. S4E-04 1.2lE-0l 

3.00E+02 1.12E-Ol 3.lSE-03 O.OOE+OO 3. 86E-OS 1.lSE-Ol 

4.00E+02 1.12E-OI 8. SSE-04 O.OOE+OO 9.6SE-06 1.!3E-OI 

S.OOE+02 1.12E-Ol 2.3IE-04 O.OOE+OO 2.4lE-06 1.12E-Ol 

6.00E+02 1.l1E-0l 6.l9E-05 O.OOE+OO 6.03E-07 1.12E-OI 

7.00E+02 l.llE-OI 1.6SE-OS O.OOE+OO I.SlE-07 l.llE-OI 

8.00E+02 1.1IE-0l 4.39E-06 O.OOE+OO 3.77E-08 1.llE-OI 

9.00E+02 1.1OE-Ol 1.16E-06 O.OOE+OO O.OOE+OO 1.1OE-Ol 

I.OOE+03 1.IOE-Ol 3.08E-07 O.OOE+OO O.OOE+OO 1.lOE-0l 

3.00E+03 I.04E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-Ol 

S.OOE+03 9. 78E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.78E-02 

7.00E+03 9.24E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 24E-02 

9.00E+03 8. 73E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 73E-02 

1.OOE+04 8. 48E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 48E-02 

B-347 
CLASS " AKA» = 1 MICR.ON BALFLIFE= 8.18E+06 DAYS PLUTONIUM 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-ROPR ACCUMULATED 24-ROUR ACCUHULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 3.0SE-OS 3.4IE-OS 

2.00E-OI 6. 46E-OS 2.19E-04 

3.00E-OI 9. 69E-05 9.IIE-04 

4.00E-OI I. 28E-04 2. 53E-03 

5.00E-OI I.S7E-04 5.4IE-03 

6.00E-OI 1.8SE-04 9.77E-03 

7.00E-OI 2.llE-04 1.S7E-02 

8.00E-01 2. 36E-04 2. 32E-02 

9.00E-01 2.60E-04 3.2IE-02 

1.OOE+OO 2. 83E-04 2. 83E-04 4. 24E-02 4. 24E-02 

2.00E+OO 1. 76E-04 4.S9E-04 1. 36E-Ol 1.78E-0l 

3.00E+OO 1.l2E-04 S.72E-04 1.l4E-Ol 2. 92E-OI 

4.00E+OO 7.S3E-OS 6. 47E-04 6.65E-02 3. 59E-Ol 

S.OOE+OO 5. 39E-05 7.0lE-04 3. 42E-02 3. 93E-01 

6.00E+OO 4.lSE-05 7. 42E-04 1.7IE-02 4.10E-Ol 

7.00E+OO 3. 42E-OS 7. 76E-04 8.8lE-03 4.l9E-Ol 

8.00E+OO 2.98E-OS 8.06E-04 4. 86E-03 4.24E-Ol 

9.00E+OO 2.7lE-05 8. 33E-04 2. 99E-03 4. 27E-Ol 

1.00E+Ol 2.S4E-05 8. 59E-04 2.09E-03 4.29E-Ol 

2.00E+Ol 2.0lE-05 I.08E-03 1.lOE-03 4.41E-Ol 

3.00E+OI 1. 76E-OS 1. 26E-03 9. S9E-04 4.S2E-Ol 

4.00E+Ol 1.S8E-OS 1. 43E-03 8.3SE-04 4.6lE-Ol 

S.OOE+Ol 1.4SE-OS 1.S8E-03 7. 28E-04 4. 68E-Ol 

6.00E+Ol 1. 36E-05 1.72E-03 6. 34E-04 4.7SE-Ol 

7.00E+Ol 1. 28E-05 1.8SE-03 S.53E-04 4.8lE-0l 

8.00E+Ol I. 22E-05 1. 98E-03 4. 82E-04 4. 86E-Ol 

9.00E+Ol 1.16E-05 2.09E-03 4.2lE-04 4.9IE-Ol 

I.OOE+02 1.12E-05 2.2lE-03 3. 67E-04 4. 94E-Ol 

2.00E+02 7. 89E-06 3.l4E-03 9.62E-OS S.lSE-Ol 

3.00E+02 S.84E-06 3. 82E-03 2. 73E-OS S.20E-Ol 

4.00E+02 4. 49E-06 4. 33E-03 9.42E-06 S.22E-0l 

S.OOE+02 3.S9E-06 4. 73E-03 4. 46E-06 S.22E-Ol 

6.00E+02 2. 99E-06 5.06E-03 2. 89E-06 5.23E-OI 

7.00E+02 2. 57E-06 S.34E-03 2. 28E-06 S.23E-Ol 

8.00E+02 2. 29E-06 S.S8E-03 1.97E-06 S.23E-Ol 

9.00E+02 2.l0E-06 S.80E-03 1. 79E-06 5. 23E-Ol 

1.OOE+03 1. 96E-06 6.00E-03 1.67E-06 S.23E-Ol .. 3.00E+03 1.S9E-06 9.34E-03 1. 35E-06 S.26E-Ol 

S.OOE+03 1. SOE-06 l.24E-02 1.28E-06 S.29E-Ol 

7.00E+03 1.42E-06 I.S3E-02 1.2lE-06 S.31E-Ol 

9.00E+03 1.34E-06 l.8lE-02 1.14E-06 5.33E-Ol 

1.OOE+04 1.30E-06 1.94E-02 1.l1E-06 5.34E-Ol 

B-348 
CLASS W AMAD = 1 MICRON HAULl)!E- 2. 39E+06 DAYS PLIITONIUM. 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 7.09E-02 2.76E-Ol 2.35E-Ol 5.72E-02 6.39E-Ol 

2.00E-Ol 7.l0E-02 2. 65E-Ol 1.97E-OI 1.OSE-Ol 6. 39E-Ol 

3.00E-Ol 7.l0E-02 2.S6E-Ol l.66E-Ol 1.46E-Ol 6.38E-Ol 

4.00E-Ol 7.l0E-02 2.47E-Ol 1. 39E-Ol 1. 79E-Ol 6.36E-Ol 

S.OOE-Ol 7.l0E-02 2.40E-Ol 1.17E-Ol 2.06E-0l 6. 34E-Ol 

6.00E-Ol 7.l0E-02 2. 33E-Ol 9. 86E-02 2. 27E-Ol 6.29E-Ol 

7.00E-Ol 7.l0E-02 2.27E-Ol 8. 29E-02 2.43E-OI 6.23E-OI 

8.00E-OI 7.10E-02 2.2IE-OI 6. 97E-02 2.S4E-OI 6.16E-OI 

9.00E-OI 7.lOE-02 2.16E-Ol S.86E-02 2.6IE-OI 6.07E-OI 

1.OOE+OO 7.l0E-02 2. lIE-OI 4. 93E-02 2.6SE-OI S.96E-OI 

2.00E+OO 7.l2E-02 1.77E-Ol 8.72E-03 2.04E-Ol 4.6lE-Ol 

3.00E+OO 7.l5E-02 1.60E-Ol 1.S4E-03 1.13E-Ol 3. 46E-Ol 

4.00E+OO 7.l9E-02 1. SOE-Ol 2.72E-04 5.72E-02 2.80E-Ol 

S.OOE+OO 7. 23E-02 1.4SE-Ol 4. 82E-OS 2. 85E-02 2.45E-Ol 

6.00E+OO 7.27E-02 1.4IE-Ol 8.SIE-06 1.47E-02 2.28E-Ol 

7.00E+OO 7.3lE-02 1. 38E-Ol 1.SlE-06 8.l4E-03 2.l9E-Ol 

8.00E+OO 7.3SE-02 1.36E-Ol 2. 66E-07 5.04E-03 2.14E-Ol 

9.00E+OO 7.40E-02 1. 34E-Ol 4.70E-08 3.SSE-03 2.llE-Ol 

1.OOE+0l 7. 44E-02 1.32E-Ol O.OOE+OO 2.82E-03 2.09E-Ol 

2.00E+Ol 7. 85E-02 1.16E-Ol O.OOE+OO 1. 87E-03 1. 97E-Ol 

3. (lOE+Ol 8. 22E-02 I.02E-Ol O.OOE+OO 1.63E-03 1.86E-OI 

4.00E+Ol 8.S6E-02 9.0lE-02 O.OOE+OO 1. 42E-03 1. 77E-Ol 

5.00E+Ol 8.87E-02 7.93E-02 O.OOE+OO 1. 24E-03 1.69E-OI 

6.00E+Ol 9.l5E-02 6.9BE-02 O.OOE+OO I.08E-03 1. 62E-Ol 

7.00E+Ol 9.40E-02 6.l4E-02 O.OOE+OO 9.36E-04 1.S6E-Ol 

8.00E+Ol 9. 62E-02 S.40E-02 O.OOE+OO 8.lSE-04 1.SlE-Ol 

9.00E+Ol 9.82E-02 4.7SE-02 O.OOE+OO 7.09E-04 1.46E-Ol 

1.OOE+02 1.OOE-Ol 4.lBE-02 O.OOE+OO 6.17E-04 1. 42E-Ol 

2.00E+02 1.1OE-OI l.lSE-02 O.OOE+OO 1.54E-04 1.2IE-Ol 

3.00E+02 1.12E-Ol 3.lSE-03 O.OOE+OO 3. 86E-OS 1.ISE-Ol 

4.00E+02 1.12E-Ol B.SSE-04 O.OOE+OO 9.6SE-06 1.l3E-OI 

S.OOE+02 1.12E-OI 2.3lE-04 O.OOE+OO 2.4IE-06 1.12E-OI 

6.00E+02 l.llE-Ol 6.l9E-OS O.OOE+OO 6.03E-07 1.12E-Ol 

7.00E+02 1.1IE-Ol 1.6SE-05 O.OOE+OO 1.SlE-07 1. llE-Ol 

8.00E+02 1.1lE-0l 4. 39E-06 O.OOE+OO 3.77E-08 1.11E-0i 

9.00E+02 1.IOE-Ol 1.16E-06 O.OOE+OO O.OOE+OO 1. lOE-OI 

1.OOE+03 1.lOE-0l 3.0BE-07 O.OOE+OO O.OOE+OO 1.lOE-0l 

3.00E+03 I.03E-Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.03E-Ol 

5.00E+03 9. 77E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.77E-02 

7.00E+03 9. 23E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 23E-02 

9.00E+03 8.71E-02 O.OOE+OO O.OOE+OO O.OOE+OO B.7lE-02 

1.OOE+04 B.47E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.47E-02 

R-349 
CLASS W .AHAD - 1 MICRON HALFLIFE= 2.39E+06 DAYS PLUTONIUM 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 3.0SE-OS 3.41E-OS 

2.00E-Ol 6. 46E-OS 2. 19E-04 

3.00E-0l 9.69E-OS 9.l1E-04 

4.00E-Ol 1. 28E-04 2.S3E-03 

S.OOE-Ol 1.S7E-04 S.41E-03 

6.00E-Ol 1.8SE-04 9.77E-03 

7.00E-0l 2.11E-04 1. S7E-02 

8.00E-Ol 2. 36E-04 2. 32E-02 

9.00E-Ol 2.60E-04 3.21E-02 

1.00E+OO 2. 83E-04 2. 83E-04 4. 24E-02 4. 24E-02 

2.00E+OO 1.76E-04 4.S9E-04 1.36E-Ol 1.78E-Ol 

3.00E+OO l.l2E-04 S.72E-04 1. 14E-Ol 2. 92E-Ol 

4.00E+OO 7.S3E-OS 6. 47E-04 6.6SE-02 3.S9E-Ol 

S.OOE+OO S.39E-OS 7.0lE-04 3. 42E-02 3. 93E-Ol 

6.00E+OO 4.ISE-OS 7.42E-04 1.71E-02 4.lOE-0l 

7.00E+OO 3. 42E-OS 7. 76E-04 8.8lE-03 4. 19E-Ol 

8.00E+OO 2. 98E-OS 8.06E-04 4.86E-03 4.24E-Ol 

9.00E+OO 2.7lE-OS 8. 33E-04 2. 99E-03 4. 27E-OI 

1.OOE+Ol 2.S4E-OS 8. S9E-04 2.09E-03 4.29E-OI 

2.00E+Ol 2. OlE-OS 1.08E-03 1.lOE-03 4.4lE-Ol 

3.00E+Ol 1. 76E-OS 1.26E-03 9. S9E-04 4.S2E-OI 

4.00E+OI 1.S8E-OS 1.43E-03 8.3SE-04 4.6lE-OI 

S.OOE+Ol 1.4SE-OS 1. S8E-03 7.28E-04 4. 68E-OI 

6.00E+Ol 1.36E-OS 1. 72E-03 6. 34E-04 4.7SE-Ol 

7.00E+OI 1.28E-OS 1.8SE-03 S. S3E-04 4.8IE-Ol 

8.00E+Ol 1. 22E-OS 1. 98E-03 4. 82E-04 4. 86E-Ol 

9.00E+Ol 1.16E-OS 2.09E-03 4.21E-04 4.9lE-Ol 

1.OOE+02 1.12E-OS Z.2lE-03 3. 67E-04 4. 94'E-Ol 

2.00E+02 7. 88E-06 3.l4E-03 9. 62E-OS S.14E-Ol 

3.00E+02 S.84E-06 3. 82E-03 2. 73E-OS S.20E-01 

4.00E+02 4. 49E-06 4.33E-03 9. 42E-06 S.21E-OI 

S.OOE+02 3.S9E-06 4. 73E-03 4. 46E-06 S.22E-01 

6.00E+02 2. 99E-06 S.06E-03 2. 89E-06 S.22E-OI 

7.00E+02 2.S7E-06 S.34E-03 2. 28E-06 S.23E-01 

8.00E+02 2.29E-06 S.S8E-03 1.97E-06 S.23E-Ol 

9.00E+02 2.l0E-06 S.80E-03 1. 79E-06 5.23E-01 

I.OOE+03 1. 96E-06 6.00E-03 1.67E-06 S.23E-OI 

3.00E+03 1.S9E-06 9. 33E-03 1.3SE-06 5. 26E-01 

5.00E+03 1. SOE-06 1.24E-02 1.28E-06 5. 28E-01 

7.00E+03 1.42E-06 1. 53E-02 1.21E-06 S.30E-Ol 

9.00E+03 1. 34E-06 1.81E-02 1. 14E-06 5. 32E-Ol 

1.OOE+04 1.30E-06 1. 94E-02 1.l1E-06 5. 33E-Ol 

B-3S0 
CLASS V AMAD =: 1 KICRON HALFLIFE= 1.378+08 IlAYS PLUTONIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 7.09E-02 2.76E-OI 2.3SE-OI S.72E-02 6.39E-OI 

2.00E-OI 7. IOE-02 2.6SE-OI 1. 97E-OI I.OSE-OI 6.39E-OI 

3.00E-OI 7. IOE-02 2.S6E-OI 1. 66E-OI I.46E-OI 6.3BE-OI 

4.00E-OI 7. IOE-02 2. 47E-OI 1. 39E-OI 1. 79E-OI 6. 36E-OI 

S.OOE-Ol 7.10E"':02 2.40E-OI 1.17E-OI 2.06E-OI 6.34E-OI 

6.00E-Ol 7.l0E-02 2. 33E-Ol 9.B6E-02 2.27E-Ol 6. 29E-OI 

7.00E-OI 7.IOE-02 2.27E-OI B.29E-02 2.43E-0l 6.23E-OI 

B.OOE-OI 7. IOE-02 2.2IE-OI 6. 97E-02 2.S4E-OI 6.l6E-OI 

9.00E-OI 7.IOE-02 2.16E-OI S. B6E-02 2.6IE-OI 6.07E-Ol 

I.OOE+OO 7. IOE-02 2.11E-OI 4. 93E-02 2.6SE-OI S.96E-OI 

2.00E+OO 7.12E-02 1. 77E-OI B.72E-03 2.04E-OI 4.6IE-OI 

3.00E+OO 7. ISE-02 1.60E-OI I.S4E-03 1. l3E-OI 3.46E-OI 

4.00E+OO 7.19E-02 1. SOE-Ol 2. 72E-04 S.72E-02 2.BOE-Ol 

S.OOE+OO 7. 23E-02 I.4SE-Ol 4.B2E-OS 2. BSE-02 2.4SE-OI 

6.00E+OO 7. 27E-02 I.4lE-OI B.SIE-06 I.47E-02 2.2BE-OI 

7.00E+OO 7.3IE-02 I.3BE-OI I.SIE-06 8.l4E-03 2.19E-Ol 

B.OOE+OO 7.3SE-02 1. 36E-OI 2.66E-07 S.04E-03 2.14E-OI 

9.00E+OO 7.40E-02 1.34E-OI 4.70E-OB 3.SSE-03 2.llE-OI 

I.OOE+OI 7.44E-02 1.32E-OI O.OOE+OO 2. B2E-03 2.09E-OI 

2.00E+0l 7. BSE-02 I.I6E-OI O.OOE+OO I.B7E-03 1.97E-OI 

3.00E+OI B.22E-02 1.02E-OI O.OOE+OO I.63E-03 I.B6E-Ol 

4.00E+OI B.S6E-02 9.OlE-02 O.OOE+OO I.42E-03 1. 77E-OI 

S.OOE+OI B.B7E-02 7. 93E-02 O.OOE+OO 1. 24E-03 I.69E-Ol 

6.00E+OI 9. ISE-02 6.9BE-02 O.OOE+OO I.OBE-03 I. 62E-OI 

7.00E+OI 9.40E-02 6.l4E-:02 O.OOE+OO 9.36E-04 I.S6E-Ol 

B.OOE+OI 9. 62E-02 S.40E-02 O.OOE+OO 8. ISE-04 I.SIE-OI 

9.00E+Ol 9.B2E-02 4.7SE-02 O.OOE+OO 7.09E-04 I.46E-OI 

I.OOE+02 I.OOE-Ol 4.1BE-02 O.OOE+OO 6.IBE-04 1.42E-OI 

2.00E+02 I.IOE-Ol I.lSE-02 O.OOE+OO 1. S4E-04 I.2IE-Ol 

3.00E+02 1.12E-OI 3.lSE-03 O.OOE+OO 3.B6E-OS 1.ISE-OI 

4.00E+02 I.I2E-OI B.55E-04 O.OOE+OO 9.65E-06 1.I3E-OI 

S.OOE+02 I.I2E-OI 2.3IE-04 O.OOE+OO 2.4IE-06 I.12E-OI 

6.00E+02 I.IIE-Ol 6.l9E-05 O.OOE+OO 6.03E-07 I.I2E-OI 

7.00E+02 1.1lE-OI 1.65E-05 O.OOE+OO I.5IE-07 1. llE-OI 

B.OOE+02 I.llE-OI 4.40E-06 O.OOE+OO 3.77E-08 I.llE-OI 

9.00E+02 1. IOE-OI 1.16E-06 O.OOE+OO O.OOE+OO I.IOE-OI 

I.OOE+03 1. IOE-OI 3.0BE-07 O.OOE+OO O.OOE+OO 1.lOE-Ol 

3.00E+03 I.04E-OI O.OOE+OO O.OOE+OO O.OOE+OO 1.04E-OI 

S.OOE+03 9. 79E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.79E-02 

7.00E+03 9. 25E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.2SE-02 

9.00E+03 B.73E-02 O.OOE+OO O.OOE+OO O.OOE+OO B.73E-02 

I.OOE+04 8. 49E-02 O.OOE+OO O.OOE+OO O.OOE+OO B.49E-02 

B-351 
CLASS W AMAD == 1 MICRON HALFLIFE= 1.37E+08 DAYS PLUTONIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 3.05E-05 3.4IE-05 

2.00E-OI 6.46E-05 2.19E-04 

3.00E-OI 9. 69E-05 9. llE-04 

4.00E-OI 1. 28E-04 2. 53E-03 

S.OOE-OI I.S7E-04 S.4IE-03 

6.00E-OI 1.85E-04 9.77E-03 

7.00E-OI 2.11E-04 1. S7E-02 

S.OOE-Ol 2. 36E-04 2.3ZE-OZ 

9.00E-Ol Z.60E-04 3.ZIE-OZ 

I.OOE+OO 2.S3E-04 2. 83E-04 4. 24E-OZ 4.Z4E-OZ 

2.00E+OO 1. 76E-04 4.S9E-04 I.36E-OI 1. 78E-OI 

3.00E+OO I.I2E-04 5.72E-04 I.I4E-OI 2. 92E-OI 

4.00E+OO 7.S3E-OS 6. 47E-04 6.6SE-02 3.S9E-OI 

S.OOE+OO S.39E-OS 7.0IE-04 3.4ZE-02 3. 93E-OI 

6.00E+OO 4.ISE-OS 7.42E-04 I.7IE-02 4.10E-OI 

7.00E+OO 3. 42E-OS 7. 76E-04 S.8IE-03 4.19E-OI 

S.OOE+OO 2. 98E-05 8.06E-04 4.86E-03 4.Z4E-OI 

9.00E+OO 2.7lE-OS 8.33E-04 2. 99E-03 4. 27E-OI 

I.OOE+OI 2.S4E-OS 8.S9E-04 2.09E-03 4.Z9E-OI 

2.00E+OI 2.0IE-OS I.08E-03 l.lOE-03 4.4IE-OI 

3.00E+OI 1. 76E-OS 1.26E-03 9. S9E-04 4.S2E-OI 

4.00E+OI I.S8E-OS 1. 43E-03 8.3SE-04 4.6IE-OI 

S.OOE+OI I.4SE-OS I.S8E-03 7.28E-04 4. 68E-OI 

6.00E+OI 1. 36E-OS I.72E-03 6. 34E-04 4.7SE-OI 

7.00E+OI 1. 28E-OS 1.8SE-03 S. S3E-04 4. SIE-Ol 

8.00E+OI 1.2ZE-05 1.9SE-03 4.8ZE-04 4.S6E-OI 

9.00E+OI 1.16E-05 2.09E-03 4. ZIE-04 4.9IE-OI 

I.OOE+02 1.IZE-OS 2.2IE-03 3. 67E-04 4. 94E-OI 

2.00E+OZ 7. 89E-06 3.14E-03 9. 62E-OS 5.I5E-OI 

3.00E+02 S.84E-06 3.8ZE-03 2. 73E-OS S.ZOE-OI 

4.00E+02 4. 49E-06 4. 33E-03 9. 42E-06 S.22E-OI 

S.OOE+OZ 3.S9E-06 4. 73E-03 4. 46E-06 S.ZZE-OI 

6.00E+02 2. 99E-06 5.06E-03 2. 89E-06 S.23E-OI 

7.00E+02 2.S7E-06 S.34E-03 2. 28E-06 S.23E-OI 

8.00E+02 2.29E-06 S.S8E-03 1. 97E-06 S.23E-OI 

9.00E+02 2. IOE-06 S.80E-03 1. 79E-06 5.23E-OI 

I.OOE+03 1.96E-06 6.00E-03 I.67E-06 S.Z3E-OI 

3.00E+03 I.S9E-06 9.34E-03 1. 35E-06 S.Z6E-OI 

5.00E+03 I.50E-06 I.24E-02 1.28E-06 5. 29E-Ol 

7.00E+03 1. 42E-06 I.53E-02 1.2IE-06 5.3IE-OI 

9.00E+03 1. 34E-06 I.8IE-02 I.I4E-06 5. 34E-OI 

I.OOE+04 I.30E-06 I.94E-02 1.llE-06 5.3SE-Ol 

B-352 
CLASS W AHAD = 1 MICRON BALFLIFE... 1.58E+05 DAYS AMKR.ICIUM 241 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.95E-02 2. 76E-01 2. 35E-01 5.72E-02 6.38E-01 

2.00E-01 6. 83E-02 2. 65E-01 1.97E-01 1.05E-01 6. 36E-01 

3.00E-01 6. 73E-02 2.56E-01 1.66E-01 1.46E-01 6.34E-Ol 

4.00E-Ol 6.66E-02 2. 47E-Ol 1. 39E-Ol 1. 79E-Ol 6.32E-01 

5.00E-Ol 6.61E-02 2.40E-01 1.17E-01 2.06E-01 6.29E-Ol 

6.00E-01 6.57E-02 2.33E-01 9. 86E-02 2. 27E-01 6. 24E-01 

7.00E-01 6. 54E-02 2.27E-01 8. 29E-02 2.43E-01 6.18E-01 

8.00E-01 6. 52E-02 2.21E-01 6. 97E-02 2.54E-01 6.10E-01 

9.00E-01 6.51E-02 2.16E-01 5. 86E-02 2.61E-01 6.01E-01 

1.00E+00 6.50E-02 2. llE-01 4. 93E-02 2. 65E-01 5.90E-01 

2.00E+00 6.51E-02 1.77E-01 8.72E-03 2.03E-Ol 4.55E-Ol 

3.00E+00 6. 55E-02 1.60E-01 1. 54E-03 1. 13E-Ol 3.40E-01 

4.00E+00 6.60E-02 1.50E-01 2.72E-04 5.72E-02 2. 74E-01 

5.00E+00 6. 64E-02 1. 45E-Ol 4. 82E-05 2.85E-02 2. 39E-Ol 

6.00E+00 6. 68E-02 1.41E-01 8.51E-06 1.47E-02 2.22E-Ol 

7.00E+00 6. 73E-02 1. 38E-01 1.51E-06 8. 13E-03 2. 14E-Ol 

8.00E+00 6.77E-02 1.36E-01 2.66E-07 5.04E-03 2.09E-Ol 

9.00E+00 6~81E-02 1. 34E-01 4.70E-08 3. 55E-03 2.06E-Ol 

1.00E+01 6.86E-02 1.32E-01 O.OOE+OO 2.82E-03 2.03E-Ol 

2.00E+01 7.26E-02 1. 16E-01 O.OOE+OO 1.87E-03 1.91E-01 

3.00E+01 7. 63E-02 1.02E-01 O.OOE+OO 1.63E-03 1.80E-Ol 

4.00E+01 7.96E-02 9.01E-02 O.OOE+OO 1.42E-03 1.71E-Ol 

5.00E+01 8.26E-02 7.93E-02 O.OOE+OO 1. 23E-03 1.63E-01 

6.00E+Ol 8.53E-02 6. 98E-02 O.OOE+OO 1.07E-03 1. 56E-01 

7.00E+01 8.77E-02 6. 14E-02 O.OOE+OO 9.36E-04 1.50E-01 

8.00E+01 8.99E-02 5.40E-02 O.OOE+OO 8. 14E-04 1.45E-Ol 

9.00E+01 9. 19E-02 4. 75E-02 0.00£+00 7.09E-04 1.40E-01 

1.00E+02 9.36E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1.36E-01 

2.00E+02 1.04E-Ol 1. 15E-02 O.OOE+OO 1.54E-04 1.15E-01 

3.00E+02 1.07E-01 3. 15E-03 O.OOE+OO 3. 86E-05 1.lOE-01 

4.00E+02 1.07E-01 8.54E-04 O.OOE+OO 9.62E-06 1.08E-Ol 

5.00E+02 1.07E-Ol 2.31E-04 O.OOE+OO 2.41E-06 1.07E-01 

6.00E+02 1.07E-01 6.17E-05 O.OOE+OO 6.02E-07 1.07E-01 

7.00E+02 1.07E-01 1.65E-05 O.OOE+OO 1.51E-07 1.07E-01 

8.00E+02 1.06E-01 4. 38E-06 O.OOE+OO 3. 76E-08 1.06E-Ol > • 9.00£+02 1.06E-01 1. 16E-06 O.OOE+OO O.OOE+OO 1.06E-Ol 

"' 1.00E+03 1.06E-Ol 3.07E-07 O.OOE+OO O.OOE+OO 1.06E-01 

3.00E+03 9. 76E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 76E-02 

5.00E+03 9.07E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-02 

7.00E+03 8.43E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8.43E-02 

9.00E+03 7. 84E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 84E-02 

1.00E+04 7.57E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 57E-02 

B-353 
CLASS W AKAD == 1 MICRON BALFLIFE= 1. SSE+OS DAYS AMERICIUM. 241 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUHULATED 24-HOUR ACCUHULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.49E-03 B.IOE-06 

2.00E-Ol 2.B4E-03 1. 64E-04 

3.00E-0l 3. 87E-03 8.29E-04 

4.00E-Ol 4.6SE-03 2.42E-03 

S.OOE-Ol 5. 25E-03 5. 28E-03 

6.00E-Ol 5.70E-03 9.6lE-03 : 

7.00E-OI 6.04E-03 1.SSE-02 

8.00E-Ol 6.30E-03 2.30E-02 

9.00E-Ol 6.S0E-03 3.19E-02 

1.OOE+OO 6. 66E-03 6.66E-03 4.2lE-02 4.2lE-02 

2.00E+OO 4. 93E-04 7.l5E-03 1.35E-Ol 1.77E-Ol 

3.00E+OO 8.24E-OS 7.23E-03 l.l4E-Ol 2. 92E-Ol 

4.00E+OO 5. 49E-05 7. 29E-03 6.64E-02 3.5BE-OI· 

5.00E+OO 5.24E-05 7.34E-03 3.4IE-02 3. 92E-Ol 

6.00E+OO 5.l7E-05 7. 39E-03 1.7lE-02 4.09E-Ol 

7.00E+OO 5.llE-05 7.44E-03 B.7BE-03 4.18E-OI 

B.OOE+OO S.06E-OS 7.49E-03 4.84E-03 4. 23E-OI 

9.00E+OO S.02E-OS 7.54E-03 2. 97E-03 4. 26E-Ol 

1.OOE+OI 4. 97E-OS 7.S9E-03 2.07E-03 4.28E-OI 

2.00E+Ol 4.S6E-OS 8.07E-03 1.08E-03 4.40E-OI 

3.00E+Ol 4.l7E-OS 8.50E-03 9. 44E-04 4.S0E-Ol 

4.00E+OI 3. BIE-OS 8.90E-03 B.22E-04 4.S9E-Ol 

5.00E+Ol 3.4BE-OS 9.26E-03 7.lSE-04 4. 67E-Ol 

6.00E+Ol 3.IBE-OS 9.S9E-03 6. 23E-04 4.73E-Ol 

7.00E+Ol 2.9IE-OS 9.90E-03 S.42E-04 4. 79E-Ol 

8.00E+Ol 2.6SE-OS 1.02E-02 4.72E-04 4.B4E-Ol 

9.00E+Ol 2.43E-OS 1.04E-02 4.lIE-04 4.B9E-Ol 

l.OOE+02 2. 22E-OS I.07E-02 3.SBE-04 4. 92E-Ol 

2.00E+02 9.70E-06 l.2IE-02 8.93E-OS 5.12E-Ol 

3.00E+02 S.47E-06 I. 29E-02 2. 24E-05 S.15E-Ol 

4.00E+02 4.13E-06 1. 33E-02 5. 58E-06 5.l7E-Ol 

5.00E+02 3.71E-06 1. 37E-02 1.40E-06 5.17E-OI 

6.00E+02 3.SBE-06 1.4lE-02 3.4BE-07 S.17E-OI 

7.00E+02 3. 53E-06 1.44E-02 B.70E-OB 5.l7E-Ol 

8.00E+02 3.5lE-06 1.48E-02 2.l7E-OB S.16E-0l 

9.00E+02 3.49E-06 1.SOE-02 O.OOE+OO S.l6E-Ol 

1.OOE+03 3.4BE-06 1.S4E-02 O.OOE+OO S.16E-Ol 

3.00E+03 3.lBE-06 2.l9E-02 O.OOE+OO S.12E-Ol 

S.OOE+03 2.92E-06 2.7BE-02 O.OOE+OO 5.06E-Ol 

7.00E+03 2. 68E-06 3.3IE-02 O.OOE+OO S.02E-Ol 

9.00E+03 2.47E-06 3.80E-02 O.OOE+OO 4.98E-Ol 

1.00E+04 2.36E-06 4.02E-02 O.OOE+OO 4. 96E-Ol 

B-3S4 
CLASS W AMAD = 1 MICRON HALFLIFE= 2.69&+06 DAYS AKER.ICIUM 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.95E-02 2. 76E-01 2.35E-01 5.72E-02 6. 38E-01 

2.00E-01 6.83E-02 2.65E-01 1.97E-01 1.05E-01 6.36E-01 

3.00E-01 6.73E-02 2. 56E-01 1. 66E-01 1.46E-01 6.34E-01 

4.00E-01 6. 66E-02 2.47E-01 1.39E-01 1.79E-01 6. 32E-01 

5.00E-01 6.61E-02 2.40E-01 1. 17E-01 2.06E-01 6.29E-01 

6.00E-01 6.57E-02 2.33E-01 9. 86E-02 2.27E-01 6.24E-01 

7.00E-01 6. 54E-02 2.27E-01 8. 29E-02 2.43E-01 6. 18E-01 

8.00E-01 6.52E-02 2.21E-01 6. 97E-02 2. 54E-01 6.lOE-01 

9.00E-01 6.51E-02 2. 16E-01 5. 86E-02 2.61E-01 6.01E-01 

1.00E+00 6.50E-02 2. llE-Ol 4. 93E-02 2. 65E-01 5.90E-01 

2.00E+00 6.51E-02 1.77E-01 8.72E-03 2.03E-01 4. 55E-01 

3.00E+00 6.55E-02 1.60E-01 1. 54E-03 1. 13E-01 3.40E-01 

4.00E+00 6.60E-02 1.50E-01 2.72E-04 5.72E-02 2. 74E-01 

5.00E+00 6.64E-02 1.45E-01 4. 82E-05 2. 85E-02 2. 39E-01 

6.00E+00 6. 68E-02 1.41E-01 8.51E-06 1.47E-02 2.22E-01 

7.00E+00 6. 73E...,.02 1. 38E-01 1.51E-06 8. 13E-03 2. 14E-01 

8.00E+00 6. 77E-02 1. 36E-01 2. 66E-07 5.04E-03 2.09E-01 

9.00E+00 6. 81E-02 1. 34E-01 4.70E-08 3. 55E-03 2.06E-Ol 

1.00E+Ol 6. 86E-02 1. 32E-01 O.OOE+OO 2.82E-03 2.03E-01 

2.00E+01 7.26E-02 1. 16E-01 O.OOE+OO 1. 87E-03 1.91E-01 

3.00E+Ol 7.63E-02 1.02E-Ol O.OOE+OO 1.63E-03 1.80E-Ol 

4.00E+01 7. 96E-02 9.01E-02 O.OOE+OO 1. 42E-03 1.71E-01 

5.00E+Ol 8. 26E-02 7.93E-02 O.OOE+OO 1.23E-03 1.63E-01 

6.00E+Ol 8. 53E-02 6.98E-02 O.OOE+OO 1.07E-03 1. 56E-Ol 

7.00E+Ol 8. 77E-02 6. 14E-02 O.OOE+OO 9. 36E-04 1.50E-Ol 

8.00E+01 8. 99E-02 5.40E-02 O.OOE+OO 8. 14E-04 1. 45E-01 

9.00E+Ol 9. 19E-02 4.75E-02 O.OOE+OO 7.09E-04 1.40E-Ol 

1.00E+02 9.36E-02 4. 18E-02 O.OOE+OO 6. 17E-04 1. 36E-01 

2.00E+02 1.04E-01 1. 15E-02 O.OOE+OO 1.54E-04 1. 15E-01 

3.00E+02 1.07E-01 3. 15E-03 O.OOE+OO 3. 86E-05 1.10E-01 

4.00E+02 1.07E-01 8.55E-04 O.OOE+OO 9. 64E-06 1.08E-Ol 

5.00E+02 1.07E-01 2. 31E-04 O.OOE+OO 2.41E-06 1.07E-01 

6.00E+02 1.07E-01 6. 19E-05 O.OOE+OO 6.03E-07 1.07E-01 

7.00E+02 1.07E-01 1. 65E-05 O.OOE+OO 1. 51E-07 1.07E-01 

8.00E+02 1.06E-01 4. 39E-06 O.OOE+OO 3.77E-08 1.06E-01 

9.00E+02 1.06E-01 1. 16E-06 O.OOE+OO O.OOE+OO 1.06E-01 "' .... "., ."" " 1.00E+03 1.06E-01 3.08E-07 O.OOE+OO O.OOE+OO 1.06E-Ol 

3.00E+03 9.88E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 88E-02 

5.00E+03 9.26E-02 O.OOE+OO O.OOE+OO O.OOE+OO 9. 26E-02 

7.00E+03 8. 68E-02 O.OOE+OO O.OOE+OO O.OOE+OO 8. 68E-02 

9.00E+03 8. 14E-02 O.OOE+OO O.OOE+oo O.OOE+OO 8. 14E-02 

1.00E+04 7. 89E-02 O.OOE+OO O.OOE+OO O.OOE+OO 7. 89E-02 

B-355 
CLASS W AHAD ... 1 MICRON MLFLIFE= 2.69£+06 DAYS AMKlUCIUK 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.49E-03 8.10E-06 

2.00E-Ol 2. 84E-03 1. 64E-04 

3.00E-Ol 3.87E-03 8. 29E-04 

4.00E-Ol 4. 65E-03 2. 42E-03 

5.00E-Ol 5.25E-03 5. 28E-03 

6.00E-Ol 5.70E-03 9.61E-03 

7.00E-Ol 6.04E-03 1.55E-02 

B.OOE-Ol 6.30E-03 2.30E-02 

9.00E-Ol 6.50E-03 3. 19E-02 

1.00E+00 6. 66E-03 6. 66E-03 4.21E-02 4. 21E-02 

2.00E+00 4. 93E-04 7. 15E-03 1.35E-Ol 1.77E-Ol 

3.00E+00 B.24E-05 7. 23E-03 1. 14E-Ol 2. 92E-Ol 

4.00E+00 5.49E-05 7. 29E-03 6.64E-02 3.5BE-Ol 

5.00E+00 5. 24E-05 7. 34E-03 3.41E-02 3. 92E-Ol 

6.00E+00 5. 17E-05 7. 39E-03 1.71E-02 4.09E-Ol 

7.00E+00 5. llE-05 7. 44E-03 8. 78E-03 4. 18E-Ol 

B.OOE+OO 5.06E-05 7.49E-03 4.B4E-03 4.23E-Ol 

9.00E+00 5.02E-05 7. 54E-03 2. 97E-03 4. 26E-Ol 

1.00E+01 4. 97E-05 7. 59E-03 2.07E-03 4. 28E-Ol 

2.00E+Ol 4. 56E-05 B.07E-03 1.0BE-03 4.40E-01 

3.001:+01 4. 17E-05 8.50E-03 9.44E-04 4.50E-Ol 

4.00E+Ol 3. 81E-05 8.90E-03 8. 22E-04 4. 59E-01 

5.00E+Ol 3.4BE-05 9. 26E-03 7. 15E-04 4.67E-01 

6.00E+Ol 3. 18E-05 9. 59E-03 6. 23E-04 4. 73E-Ol 

7.00E+OI 2. 91E-05 9.90E-03 5. 42E-04 4.79E-01 

8.00E+OI 2. 65E-05 1.02E-02 4.72E-04 4.B4E-Ol 

9.00E+OI 2. 43E-05 1.04E-02 4.11E-04 4.B9E-OI 

1.00E+02 2. 22E-05 1.07E-02 3.5BE-04 4. 92E-Ol 

2.00E+02 9. 71E-06 1.21E-02 B.94E-05 5. 12E-Ol 

3.00E+02 5.4BE-06 1. 29E-02 2. 24E-05 5. 16E-Ol 

4.00E+02 4. 14E-06 1.33E-02 5.59E-06 5.1BE-01 

5.00E+02 3. 72E-06 1. 37E-02 1.40E-06 5. 18E-01 

6.00E+02 3. 59E-06 1.41E-02 3.49E-07 5.1BE-01 

7.00E+02 3. 54E-06 1. 44E-02 B.73E-08 5.1BE-01 " !". 8.00E+02 3.52E-06 1.48E-02 2. 18E-OB 5. 18E-01 

9.00E+02 3.50E-06 1. 51E-02 0.00£+00 5.1BE-01 

1.00E+03 3. 49E-06 1.55£-02 O.OOE+OO 5.1BE-Ol 

3.00E+03 3.22E-06 2. 22E-02 O.OOE+OO 5.1BE-01 

5.00E+03 2.9BE-06 2. 84E-02 O.OOE+OO 5. 17E-01 

7.00E+03 2. 76E-06 3.41E-02 O.OOE+OO 5.17E-01-

9.00E+03 2.47E-06 3. BOE-02 O.OOE+OO 4.9BE-01 

1.00E+04 2. 36E-06 4.02E-02 O.OOE+OO 4. 96E-01 

B-356 
ClASS W AKAD = 1 MICRON BALFLIFE- 1.63E+o2 DAYS CURIUH 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 6.95E-02· 2. 76E-01 2.35E-01 5.71E-02 6.37E-01 

2.00E-01 6. 82E-02 2. 65E-01 1.97E-01 1.05E-01 6. 36E-01 

3.00E-01 6. 72E-02 2.55E-01 1.66E-01 1.45E-01 6.34E-01 

4.00E-01 6. 65E-02 2. 47E-01 1. 39E-01 1. 78E-01 6.31E-01 

5.00E-01 6. 59E-02 2. 39E-01 1.17E-01 2.05E-01 6.27E-01 

6.00E-01 6. 55E-02 2. 32E-01 9. 84E-02 2. 26E-01 6.22E-01 

7.00E-01 6. 52E-02 2. 26E-01 8. 27E-02 2. 42E-01 6. 16E-01 

8.00E-01 6.50E-02 2.20E-01 6. 95E-02 2. 53E-01 6.08E-01 

9.00E-01 6.48E-02 2. 15E-01 5. 84E-02 2.60E-01 5.98E-01 

1.00E+00 6.47E-02 2.10E-01 4. 91E-02 2. 64E-01 5. 88E-01 

2.00E+00 6. 45E-02 1.76E-01 8.64E-03 2.02E-01 4.51E-01 

3.00E+00 6.47E-02 1. 58E-01 1. 52E-03 1. 12E-01 3. 36E-01 

4.00E+00 6. 48E-02 1.48E-01 2.68E-04 5. 62E-02 2.69E-01 

5.00E+00 6.50E-02 1.42E-01 4.71E-05 2. 79E-02 2. 34E-01 

6.00E+00 6. 52E-02 1.37E-01 8.30E-06 1.43E-02 2.17E-01 

7.00E+00 6. 53E-02 1.34E-01 1.46E-06 7.90E-03 2.07E-01 

8.00E+00 6. 54E-02 1. 31E-01 2. 57E-07 4. 87E-03 2.02E-01 

9.00E+00 6. 56E-02 1.29E-01 4. 53E-08 3.41E-03 1. 98E"':01 

1.00E+01 6. 57E-02 1.27E-01 O.OOE+OO 2.70E-03 1. 95E-01 

2.00E+01 6. 67E-02 1.07E-01 O.OOE+OO 1.72E-03 1.75E-01 

3.00E+01 6.71E-02 9.00E-02 O.OOE+OO 1. 43E-03 1.59E-01 

4.00E+01 6.71E-02 7.60E-02 O.OOE+OO 1.20E-03 1.44E-01 

5.00E+01 6. 67E-02 6.41E-02 O.OOE+OO 9.98E-04 1.32E-01 

6.00E+01 6.60E-02 5.40E-02 O.OOE+OO 8. 32E-04 1.21E-01 

7.00E+01 6.51E-02 4. 56E-02 O.OOE+OO 6.94E-04 1. 11E-01 

8.00E+01 6.40E-02 3. 84E-02 O.OOE+OO 5. 79E-04 1.03E-01 

9.00E+01 6.26E-02 3. 24E-02 O.OOE+OO 4.83E-04 9.55E-02 

1.00E+02 6. 12E-02 2. 73E-02 O.OOE+OO 4.03E-04 8. 89E-02 

2.00E+02 4.42E-02 4.92E-03 O.OOE+OO 6.59E-05 4. 92E-02 

3.00E+02 2. 97E-02 8. 79E-04 O.OOE+OO 1.08E-05 3.06E-02 

4.00E+02 1.95E-02 1.56E-04 O.OOE+OO 1.76E-06 1.97E-02 

5.00E+02 1. 28E-02 2. 74E-05 O.OOE+OO 2.87E-07 1. 28E-02 

6.00E+02 8.31E-03 4.81E-06 O.OOE+OO 4.69E-08 8. 32E-03 

7.00E+02 5.41E-03 8.39E-07 O.OOE+OO O.OOE+OO 5.42E-03 

8.00E+02 3. 53E-03 1. 46E"';'07 O.OOE+OO O.OOE+OO 3. 53E-03 

9.00E+02 2.30E-03 2. 52E-08 O.OOE+OO O.OOE+OO 2.30E-03 

f:,;.· ., 1.00E+03 1.49E-03 O.OOE+OO O.OOE+OO O.OOE+OO 1.49E-03 I" . • <; 

.-" '" " !, 2.00E+03 2.05E-05 O.OOE+OO O.OOE+OO O.OOE+OO 2.05E-05 

3.00E+03 2.80E-07 O.OOE+OO O.OOE+OO O.OOE+OO 2.80E-07 

B-357 
CLASS V AHAD = 1 MICRON BALFLIFB= 1.63£+02 DAYS CURIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1. 49E-03 8.lOE-06 

2.00E-Ol 2.S4E-03 1. 64E-04 

3.00E-Ol 3.S7E-03 S.2SE-04 

4.00E-Ol 4. 64E-03 2. 42E-03 

S.OOE-Ol S.23E-03 S.27E-03 

6.00E-Ol S.6SE-03 9. 59E-03 

7.00E-Ol 6.02E-03 1.SSE-02 

8.00E-Ol 6.2SE-03 2. 29E-02 

9.00E-Ol 6. 48E-03 3.lSE-02 

l.OOE+OO 6. 63E-03 6. 63E-OJ 4.20E-02 4.20E-02 

2.00E+OO 4.89E-04 7.09E-03 1.34E-Ol 1.76E-Ol 

3.00E+OO 8.l3E-05 7.l4E-03 1.l3E-Ol 2. 88E-Ol 

4.00E+OO 5.40E-05 7.17E-03 6.53E-02 3. 52E-Ol 

5.00E+OO 5.l3E-05 7.19E-OJ 3. 34E-02 3.S4E-Ol 

6.00E+OO S.04E-05 7. tLE-03 1.66E-02 3. 99E-Ol 

7.00E+OO 4.96E-05 7.2JE-03 8. 52E-03 4.06E-Ol 

8.00E+OO 4.90E-05 7. 24E-03 4.67E-03 4.09E-Ol 

9.00E+OO 4. 83E-05 7. 26E-03 2.8SE-03 4.10E-Ol 

1.OOE+Ol 4. 77E-OS 7.28E-03 1.98E-OJ 4.lOE-Ol 

2.00E+Ol 4.18E-05 7.41E-03 9. 96E-04 4.04E-Ol 

3.00E+Ol 3. 67E-05 7. 48E-03 8.31E-04 3. 96E-Ol 

4.00E+Ol 3.21E-05 7.51E-03 6. 93E-04 3. 87E-Ol 

S.OOE+Ol 2.81E-05 7. 49E-03 5.78E-04 3.17E-Ol 

6.00E+Ol 2. 46E-05 7. 43E-03 4. 82E-04 3. 67E-Ol 

7.00E+Ol 2.16E-05 7.3SE-03 4.02E-04 3:56E-Ol 

8.00E+Ol 1. 89E-05 7. 24E-03 3. 36E-04 3. 44E-Ol 

9.00E+Ol 1. 65E-05 7.11E-03 2.80E-04 3. 33E-Ol 

1.OOE+02 1. 45E-05 6. 96E-03 2. 34E-04 3. 22E-Ol 

2.00E+02 4. 15E-06 5.18E-03 3.82E-OS 2.1SE-Ol 

3.00E+02 1. 53E-06 3.SSE-03 6.23E-06 1. 44E-Ol 

4.00E+02 7.53E-07 2. 43E-03 1.02E-06 9. 43E-02 

5.00E+02 4.43E-07 1.6JE-03 1.66E-07 6. 16E-02 

6.00E+02 2. 79E-07 1.09E-03 2.11E-08 4.03E-02 

7.00E+02 1.80E-07 7.JJE-04 O.OOE+OO 2. 63E-02 

8.00E+02 1.17E-07 4.90E-04 O.OOE+OO 1.72E-02 

9.00E+02 7.59E-08 3. 28E-04 O.OOE+OO 1. 12E-02 

1.00E+03 4.94E-08 2. 19E-04 O.OOE+OO 7.33E-03 

B-35S 
6~£-H 

S'lOS01lD 1. S!WI:J .iO 

ROI.T.V1VBtlI :il'l9NIS 1I0iI SNOIJ.:JVlIiI NOIJ.3.lI:JX3 OIlY NOIJJl:u.n: iIO sn1lY.T. • ., 

. ,: ~. . 
CLASS Y AMAD = 1 MICRON' STABLE BERYLLIUM 9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 3.6lE-03 3.04E-Ol 2. 58E-Ol 7.30E-02 6. 39E-OI 

2.00E-Ol 3. 47E-03 2. 85E-OI 2.l7E-Ol 1.33E-Ol 6.38E-Ol 

3.00E-OI 3.43E-03 2.70E-Ol 1. 82E-OI 1.81E-0l 6. 37E-Ol 

4.00E-OI 3.45E-03 2.57E-Ol 1.53E-Ol 2.2IE-Ol 6. 35E-Ol 

5.00E-Ol 3. 48E-03 2.47E-Ol 1.29E-Ol 2.52E-0l 6.3IE-Ol 

6.00E-Ol 3.5IE-03 2. 38E-OI 1.08E-OI 2. 75E-OI 6.26E-OI 

7.00E-Ol 3. 54E-03 2.3IE-Ol 9.12E-02 2.92E-Ol 6.18E-Ol 

8.00E-Ol 3. 57E-03 2. 24E-Ol 7.67E-02 3.04E-Ol 6.09E-OI 

9.00E-OI 3. 59E-03 2.19E-OI 6. 45E-02 3.lIE-OI 5.98E-OI 

1.OOE+OO 3.6lE-03 2.l3E-Ol 5. 42E-02 3.l4E-OI 5. 85E-OI 

2.00E+OO 3.66E-03 I.80E-Ol 9.59E-03 2.3IE-Ol 4. 25E-Ol 

3.00E+OO 3. 67E-03 I.65E-Ol I.70E-03 1. 24E-Ol 2. 94E-Ol 

4.00E+OO 3. 66E-03 1. 57E-Ol 3.00E-04 6.04E-02 2.2IE-OI 

5.00E+OO 3. 64E-03 1.53E-OI S.30E-OS 2. 84E-02 1. 85E-Ol 

6.00E+OO 3.62E-03 1.SlE-OI 9.37E-06 1. 34E-02 I.68E-OI 

7.00E+OO 3. 59E-03 I.49E-Ol 1. 66E-06 6.40E-03 1.59E-OI 

8.00E+OO 3.57E-03 1.49E-OI 2.93E-07 3.16E-03 1.56E-OI 

9.00E+OO 3. 55E-03 1.48E-OI 5.17E-08 1. 64E-03 1.54E-Ol 

I.OOE+OI 3. 53E-03 1.48E-OI O.OOE+OO 9.16E-04 1. 53E:-OI 

2.00E+OI 3. 37E-03 1.46E-Ol O.OOE+OO 2. 35E-04 1.50E-OI 

3.00E+OI 3. 29E-03 I.45E-0l O.OOE+OO 2.3IE-04 I.48E-OI 

4.00E+OI 3. 27E-03 I.43E-OI O.OOE+OO 2. 28E-04 1.47E-O 

5.00E+Ol 3. 28E-03 1.42E-Ol O.OOE+OO 2.25E-04 1.4 

6.00E+Ol 3.3IE-03 1.4lE-OI O.OOE+OO 2. 22E-04 I.44E-OI 

7.00E+OI 3.3SE-03 1.39E-OI O.OOE+OO 2.l9E-04 I.43E-OI 

8.00E+OI 3.40E-03 I.38E-Ol O.OOE+OO 2.16E-04 1.4IE-OI 

9.00E+OI 3.46E-03 1.36E-Ol O.OOE+OO 2.13E-04 1.40E-Ol 

1.00E+02 3. 52E-03 1.3SE-OI O.OOE+OO 2.l0E-04 1. 39E-Ol 

2.00E+02 4.l6E-03 I.22E-Ol O.OOE+OO 1.83E-04 1.26E-OI 

3.00E+02 4. 79E-03 I.IOE-OI O.OOE+OO I.59E-04 1.15E-OI 

4.00E+02 5. 39E-03 9. 98E-02 O.OOE+OO 1.38E-04 1.05E-OI 

5.00E+02 5. 96E-03 9.06E-02 O.OOE+OO 1.2IE-04 9. 66E-02 

6.00E+02 6. 49E-03 8.23E-02 O.OOE+OO I.05E-04 8. 89E-02 

7.00E+02 6. 97E-03 7.49E-02 O.OOE+OO 9.14E-05 8.20E-02 

8.00E+02 7.4IE-03 6. 83E-02 O.OOE+OO 7. 95E-05 7. 58E-02 

9.00E+02 7.8IE-03 6.23E-02 O.OOE+OO 6. 92E-05 7.02E-02 

1.OOE+03 8.17E-03 5.70E-02 O.OOE+OO 6.03E-05 6. 52E-02 

2.00E+03 9.62E-03 2.5SE-02 O.OOE+OO 1.51E-OS 3.SlE-02 

3.00E+03 8. 62E-03 1.34E-02 O.OOE+OO 3.77E-06 2.20E-02 

4.00E+03 6. 79E-03 8. 25E-03 O.OOE+OO 9.42E-07 I.SOE-02 

S.OOE+03 4. 98E-03 5. 92E-03 O.OOE+OO 2.3SE-07 1.09E-02 

7.00E+03 2. 38E-03 4. 27E-03 O.OOE+OO 1.47E-08 6. 65E-03 

8.00E+03 1.S9E-03 4.00E-03 O.OOE+OO O.OOE+OO S.S9E-03 

9.00E+03 1.OSE-03 3. 87E-03 O.OOE+OO O.OOE+OO 4.9lE-03 

I.OOE+04 6.81E-04 3.80E-03 O.OOE+OO O.OOE+OO 4. 48E-03 

2.00E+04 7.48E-06 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-360 
CLASS Y AHAD = 1 KICRON STABLE BERYLLIUM 9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3.32E-04 1.04E-05 

2.00E-Ol 6. 45E-04 2.10E-04 

3.00E-Ol 9.03E-04 1.06E-03 

4.00E-Ol 1. 12E-03 3.07E-03 

5.00E-Ol 1. 31E-03 6. 65E-03 

6.00E-Ol 1. 47E-03 1.21E-02 

7.00E-Ol 1. 62E-03 1. 94E-02 

8.00E-Ol 1. 74E-03 2. 86E-02 

9.00E-Ol 1.85E-03 3.95E-02 

1.00E+00 1.9SE-03 1. 95E-03 5. 19E-02 5. 19E-02 

2.00E+00 4. 98E:"'04 2.45E-03 1.60E-01 2. 12E-Ol 

3.00E+00 1. 63E-04 2.61E-03 1.30E-Ol . 3. 42E-Ol 

4.00E+00 8. 44E-OS 2.69E-03 7. 32E-02 4.15E-Ol 

5.00E+00 6. 15E-05 2. 75E-03 3. 62E-02 4. 52E-Ol 

6.00E+00 5. 24E-05 2.81E-03 1.72E-02 4. 69E-Ol 

7.00E+00 4. 76E-05 2.8SE-03 8.08E-03 4. 77E-Ol 

8.00E+00 4.4SE-05 2.90E-03 3.86E-03 4.81E-Ol 

9.00E+00 4. 24E-05 2. 94E-03 1.90E-03 4. 83E-Ol 

1..00E+Ol 4.06E-05 2. 98E-03 9.80E-04 4. 84E-Ol 

2.00E+Ol 2. 97E-OS 3. 32E-03 1. 35E-04 4. 86E-Ol 

3.00E+Ol 2.30E-OS 3. 58E-03 1. 32E-04 4.87E-Ol 

4.00E+Ol 1. 88E-05 3. 78E-03 1. 31E-04 4.88E-Ol 

5 .. 00E+Ol 1. 62E-05 3.96E-03 1. 29E-04 4.90E-Ol 

6.00E+Ol 1. 46E-05 4. 11E-03 1. 27E-04 4. 91E-Ol 

7.00E+Ol 1.36E-05 4. 25E-03 1.25E-04 4.92E-Ol 

8.00E+Ol 1.30E-05 4. 38E-03 1. 23E-04 4. 93E-Ol 

9.00E+Ol 1. 26E-05 4. 51E-03 1.22E-04 4.95E-Ol 

1.00E+02 1. 24E-05 4. 63E-03 1.20E-04 4. 96E-Ol 

2.00E+02 1.25E-05 5. 87E-03 1.05E-04 5.07E-Ol 

3.00E+02 1. 28E-05 7. 13E-03 9.1OE-OS 5. 17E-Ol 

4.00E+02 1.30E-05 8. 42E-03 7. 92E-05 5. 25E-Ol 

5.00E+02 1. 32E-05 9. 73E-03 6.90E-05 5. 33E-Ol 

7.00E+02 1. 32E-05 1.24E-02 5.23E-05 5. 45E-Ol 

8.00E+02 1.31E-05 1.37E-02 4. 55E-05 5.50E-Ol 

9.00E+02 1.30E-05 1.50E-02 3.96E-05 5.S4E-Ol .. 1.00E+03 1. 28E-05 1. 63E-02 3. 45E-05 5. 58E-Ol 

2.00E+03 9. 97E-06 2. 78E-02 8. 62E-06 5. 76E-Ol 

3.00E+03 7.00E-06 3. 62E-02 2. 16E-06 5. 81E-Ol 

4.00E+03 4. 71E-06 4.20E-02 5. 39E-07 5. 82E-Ol 

5.00E+03 3.10E-06 4. 59E-02 1.35E-07 5. 82E-Ol 

7.00E+03 1.30E-06 S.00E-02 O.OOE+oo 5. 82E-Ol 

8.00E+03 8. 36E-07 5. llE-02 O.OOE+OO S.82E-Ol 

9.00E+03 5. 34E-07 5. 17E-02 O.OOE+oo 5. 82E-Ol 

1.00E+04 3.40E-07 5. 22E-02 O.OOE+OO 5. 82E-Ol 

B-361 
CLASS Y AMAD = 1 MICRON STABLE FLUORINE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS· PASSAGES TRACT BODY 

I.OOE-OI 5.03E-02 3.04E-OI 2.5SE-OI 2. 67E-02 6.39E-0l 

2.00E-OI I.l3E-OI l.S5E-OI 2.l7E-OI 2. 44E-02 6.39E-OI 

3.00E-OI I.66E-Ol 2.70E-OI 1. S2E-0l 2.04E-02 6.39E-OI 

4.00E-Ol 2.IIE-OI 2. 57E-OI I. 53E-Ol 1.70E-02 6. 39E-OI 

5.00E-OI 2.49E-OI 2. 47E-Ol I.29E-Ol 1.43E-02 6.39E-Ol 

6.00E-OI 2.80E-OI 2.3SE-OI I.08E-Ol I.20E-02 6. 39E-OI 

7.00E-Ol 3.07E-OI 2.3lE-OI 9.12E-02 I.02E-02 6. 39E-OI 

8.00E-OI 3. 29E-OI 2. 24E-OI 7.67E-02 S.6SE-03 6.39E-OI 

9.00E-OI 3.49E-OI 2. 19E-OI 6.45E-02 7. 42E-03 6. 39E-Ol 

I.OOE+OO 3. 65E-OI 2.l3E-OI 5.42E-02 6.37E-03 6. 39E-OI 

2.00E+OO 4.47E-OI 1.80E-Ol 9.59E-03 1. 69E-03 6. 39E-OI 

3.00E+OO 4. 72E-OI I.6SE-OI I.70E-03 6.0IE-04 6. 39E-OI 

4.00E+OO 4.82E-OI 1.S7E-OI 3.00E-04 2.6IE-04 6. 39E-OI 

S.OOE+OO 4.S6E-Ol I.S3E-OI 5.30E-05 1. 26E-04 6. 39E-OI 

6.00E+OO 4.S9E-OI 1.5IE-OI 9.37E-06 6. 43E-05 6. 39E-OI 

7.00E+OO 4.90E-OI I.49E-0l 1. 66E-06 3.4BE-05 6.39E-OI 

S.OOE+OO 4.90E-OI I.49E-0l 2. 93E-07 2.02E-05 6. 39E-Ol 

9.00E+OO 4.91E-Ol I.4SE-Ol S.I7E-OS 1.29E-05 6.39E-OI 

I.OOE+OI 4.9IE-OI I.4SE-Ol O.OOE+OO 9.30E-06 6.39E-OI 

2.00E+Ol 4. 93E-OI 1.46E-OI O.OOE+OO 5.6lE-06 6.39E-Ot 

3.00E+Ol 4.94E-OI I.4SE-Ol O.OOE+OO S.52E-06 6.39E-OI 

4.00E+OI 4. 96E-OI I.43E-0l O.OOE+OO 5.4SE-06 6. 39E-O 

S.OOE+OI 4.97E-0l I.42E-OI O.OOE+OO S.37E-06 6.39E6.00E+OI 4.99E-OI I.4IE-OI O.OOE+OO S.30E-06 6. 39E-OI 

7.00E+OI S.OOE-OI I.39E-OI O.OOE+OO S.23E-06 6. 39E-OI 

S.OOE+OI S.OIE-Ol 1.3SE-OI O.OOE+OO S.ISE-06 6. 39E-OI 

9.00E+OI S.03E-Ol I.36E-OI O.OOE+OO S.OSE-06 6. 39E-Ol 

1.00E+02 S.04E-OI I.3SE-OI O.OOE+OO S.OIE-06 6.39E-OI 

2.00E+02 S.17E-Ol I.22E-OI O.OOE+OO 4. 36E-06 6. 39E-OI 

3.00E+02 S.29E-OI I.lOE-OI O.OOE+OO 3. BOE-06 6. 39E-OI 

4.00E+02 S.39E-0l 9.9SE-02 O.OOE+OO 3.31E-06 6.39E-OI 

S.OOE+02 S.49E-OI 9.06E-02 O.OOE+OO 2.SSE-06 6. 39E-Ol 

6.00E+02 5.S7E-Ol S.23E-02 O.OOE+OO 2.SIE-06 6. 39E-Ol 

7.00E+02 S.64E-OI 7.49E-02 O.OOE+OO 2. ISE-06 6. 39E-Ol 

8.00E+02 S.71E-Ol 6. S3E-02 O.OOE+OO 1.90E-06 6. 39E-Ol 

9.00E+02 S.77E-OI 6. 23E-02 O.OOE+OO 1.6SE-06 6. 39E-Ol 

1.00E+03 S.S2E-OI 5.70E-02 O.OOE+OO 1. 44E-06 6. 39E ... OI <, .• 2.00E+03 6. 14E-Ol 2. 55E-02 O.OOE+OO 3.60E-07 6.39E-Ol 

3.00E+03 6. 26E-Ol I. 34E-02 O.OOE+OO 9.00E-OS 6.39E-OI 

4.00E+03 6.3IE-OI S.2SE-03 O.OOE+OO 2.2SE-OB 6.39E-OI 

5.00E+03 6. 33E-OI S.92E-03 O.OOE+OO O.OOE+OO 6. 39E-OI 

7.00E+03 6.3SE-OI 4. 27E-03 O.OOE+OO O.OOE+OO 6. 39E-OI 

S.OOE+03 6.3SE-OI 4.00E-03 O.OOE+OO O.OOE+OO 6. 39E-OI 

9.00E+03 6.3SE-OI 3.S7E-03 O.OOE+OO O.OOE+OO 6. 39E-OI 

I.OOE+04 6.3SE-OI 3. SOE-03 O.OOE+OO O.OOE+OO 6.39E-OI 

2.00E+04 6.3SE-Ol 3. 74E-03 O.OOE+OO O.OOE+OO 6. 39E-OI 

B-362 
CLASS Y .AHAD = 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 97E-03 3.04E-01 2.SSE-01 7.30E-02 6.39E-Ol 

2.00E-Ol 4.2SE-03 2.SSE-01 2. 17E-01 1.33E-01 6.39E-01 

3.00E-Ol 4.70E-03 2.70E-0l 1. S2E-0l 1.SlE-Ol 6.3SE-Ol 

4.00E-Ol S.l3E-:-03 2.S7E-Ol 1.S3E-Ol 2.20E-OI 6.36E-OI 

S.OOE-Ol S.S4E-03 2. 47E-OI 1.29E-OI 2.SlE-Ol 6. 32E-Ol 

6.00E-01 S.90E-03 2. 38E-OI 1.0SE-01 2. 74E-01 6.27E-OI 

7.00E-OI 6.21E-03 2.3IE-OI 9.l2E-02 2.9IE-OI 6.20E-OI 

B.OOE-01 6.4SE-03 2.24E-OI 7. 67E-02 3.03E-OI 6. IOE-Ol 

9.00E-01 6.70E-03 2. 19E-OI 6.4SE-02 3.l0E-Ol 6.00E-OI 

I.OOE+OO 6.SSE-03 2.l3E-OI S.42E-02 3.l3E-Ol S.S7E-OI 

2.00E+OO 7.S7E-03 1. SOE-OI 9·. S9E~03 2.30E-01 4. 27E-OI 

3.00E+OO 7.S0E-03 1.6SE-Ol I.70E-03 1. 24E-Ol 2.97E-01 

4.00E+OO 7.2SE-03 I.S7E,..Ol 3.00E-04 6.00E-02 2.24E-01 

5.00E+OO 7.03E-03 1.53E-Ol 5.30E-05 2.S3E-02 1.SSE-Ol 

6.00E+OO 6.79E-03 1. SIE-Ol . 9.37E-06 1. 33E-02 1.7IE-0l 

7.00E+OO 6.S6E-03 1.49E-Ol 1. 66E-06 6. 37E-03 I.62E-01 

8.00E+OO 6.36E-03 1.49E-Ol 2. 93E-07 3.14E-03 1.SSE-0l 

9.00E+OO 6. ISE-03 1.4SE-0l 5.17E-OB 1. 63E-03 1.S6E-OI 

I.OOE+OI 6.02E-03 1.4SE-Ol O.OOE+OO 9.lIE-04 1.5SE-Ol 

2.00E+Ol 5.09E-03 1. 46E-0l O.OOE+OO 2. 34E-04 1. 52E-OI 

3.00E+Ol 4.70E-03 1.45E-Ol O.OOE+OO 2.30E-04 1.S0E-OI 

4.00E+01 4. 46E-03 1.43E-01 O.OOE+OO 2. 27E-04 1.4SE-Ol 

S.OOE+01 4. 26E-03 I.42E-01 O.OOE+OO 2. 24E-04 I.46E-01 

6.00E+OI 4.09E-03 I.4IE-01 O.OOE+OO 2.2IE-04 1. 45E-01 

7.00E+01 3. 93E-03 1.39E-01 O.OOE+OO 2.IBE-04 1. 43E-OI 

B.OOE+OI 3.7BE-03 1.3BE-OI O.OOE+OO 2.1SE-04 1. 42E-OI 

9.00E+OI 3. 64E-03 I.36E-01 O.OOE+OO 2.12E-04 1.40E-OI 

1.00E+02 3.S1E-03 1.3SE-01 O.OOE+OO 2.09E-04 1. 39E-01 

2.00E+02 2. 62E-03 1.22E-01 O.OOE+OO I.S2E-04 1. 25E-OI 

3.00E+02 2.18E-03 l.lOE-Ol O.OOE+OO 1.S8E-04 1.l3E-OI 

4.00E+02 1.9SE-03 9.9BE-02 O.OOE+OO 1.3SE-04 I.02E-01 

S.OOE+02 I.S3E-03 9.06E-02 O.OOE+OO 1.20E-04 9.2SE-02 

6.00E+02 1.7SE-03 8. 23E-02 O.OOE+OO 1.04E-04 S.42E-02 

7.00E+02 I.70E-03 7.49E-02 O.OOE+OO 9.09E-OS 7. 67E-02 

S.OOE+02 1.64E-03 6. 83E-02 O.OOE+OO 7.9lE-OS 7.00E-02 

9.00E+02 1.S9E-03 6. 23E-02 O.OOE+OO 6.S9E-OS 6.40E-02 :.\ I.OOE+03 I.S4E-03 S.70E-02 O.OOE+OO 6.00E-05 S.S6E-02 

2.00E+03 9.6IE-04 2.5SE-02 O.OOE+OO I.SOE-OS 2. 64E-02 

3.00E+03 S.29E-04 I.34E-02 O.OOE+OO 3.7SE-06 1. 39E-02 

4.00E+03 2.77E-04 S.2SE-03 O.OOE+OO 9. 37E-07 8.S3E-03 

S.OOE+03 1.4lE-04 S.92E-03 O.OOE+OO 2. 34E-07 6.06E-03 

6.00E+03 7.14E-OS 4.SIE-03 O.OOE+OO S.S6E-OS 4. SSE-03 

7.00E+03 3.S9E-OS 4.27E-03 O.OOE+OO 1. 46E-OS 4.30E-03 

S.OOE+03 I.SOE-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.02E-03 

9.00E+03 9.0IE-06 3.S7E-03 O.OOE+OO O.OOE+OO 3. BSE-03 

I.OOE+04 4.5lE-06 3.S0E-03 O.OOE+OO O.OOE+OO 3.SlE-03 

B-363 
CLASS Y AHAD= 1 MICRON STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HDUR ACCUHULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2.00E-OS 1.04E-OS 

2.00E-Ol 4. 44E-OS 2.10E-04 

3.00E-Ol 7.07E-OS 1.OSE-03 

4.00E-Ol 9.9SE-OS 3.06E-03 

S.ODE-Ol 1.31E-04 6. 64E-03 

6.00E-Ol 1. 64E-04 1.20E-02 

7.00E-Ol 1.99E-04 1. 93E-02 

8.00E-Ol 2.3SE-04 2.8SE-02 

9.00E-Ol 2. 73E-04 3. 93E-02 

1.00E+00 3. llE-04 3. llE-04 S.17E-02 S.17E-02 

2.00E+00 4.04E-04 7.1SE-04 1.S9E-01 2.11E-Ol 

3.00E+00 3. 89E-04 1.10E-03 1.30E-01 3.41E-Ol 

4.00E+00 3.S4E-04 1. 46E-03 7. 28E-02 4.13E-Ol 

S.OOE+OO 3.1BE-04 1.7BE-03 3.60E-02 4.49E-Ol 

6.00E+00 2. 84E-04 2.06E-03 1.71E-02 4. 66E-Ol 

7.00E+00 2.S3E-04 2.31E-03 8.04E-03 4. 74E-Ol 

B.OOE+OO 2. 26E-04 2.S4E-03 3. 84E-03 4. 78E-Ol 

9.00E+00 2.03E-04 2. 74E-03 1.89E-03 4.80E-Ol 

1.00E+Ol 1. 82E-04 2. 92E-03 9.7SE-04 4.81E-Ol 

2.00E+Ol 7.S6E-05 4.04E-03 1. 34E-04 4. 83E-Ol 

3.00E+Ol 4.80E-OS 4. 62E-03 1. 32E-04 4.8SE-Ol 

4.00E+Ol 4.02E-OS S.OSE-03 1.30E-04 4. 86E-Ol 

S.OOE+Ol 3. 73E-OS S.43E-03 1.28E-04 4.87E-Ol 

6.00E+Ol 3.S7E-OS S.80E-03 1. 26E-04 4.88E-Ol 

7.00E+Ol 3.4SE-OS 6.1SE-03 1.2SE-04 4.90E-Ol 

8.00E+Ol 3.3SE-OS 6.49E-03 1. 23E-04 4.91E-Ol 

9.00E+Ol 3.2SE-OS 6. 82E-03 1.21E-04 4. 92E-Ol 

1.OOE+02 3.17E-OS 7.14E-03 1. 19E-04 4. 93E-Ol 

2.00E+02 2. SSE-OS 9.96E-03 1.04E-04 S.OSE-Ol 

3.00E+02 2.2SE-OS 1. 23E-02 9.06E-OS S.14E-01 

4.00E+02 2.09E-OS 1.4SE-02 7.88E-05 S.23E-Ol 

S.00E+02 1.99E-OS 1.6SE-02 6.86E-OS S.30E-Ol 

7.00E+02 1. 86E-OS 2.04E-02 S.20E-OS S.42E-Ol 

8.00E+02 1.81E-OS 2.22E-02 4.S3E-OS 5.47E-Ol 

9.00E+02 1.7SE-OS 2.40E-02 3. 94E-OS S.SlE-Ol 

1.00E+03 1.69E-OS 2.S7E-02 3.43E-OS S.S5E-Ol 

2.00E+03 l.04E-OS 3. 93E-02 8. 58E-06 5. 73E-Ol 

3.00E+03 S.73E-06 4. 72E-02 2. ll.E-06 5. 78E-Ol 

4.00E+03 2. 99E-06 S.14E-02 S.36E-07 5. 79E-Ol 

S.00E+03 l.S3E-06 5. 36E-02 l.34E-07 5.79E-Ol 

7.00E+03 3.87E-07 5. 53E-02 O.OOE+OO S.80E-Ol 

8.00E+03 l.94E-07 S.S6E-02 O.OOE+OO S.80E-Ol 

9.00E+03 9.72E-08 5. 57E-02 O.OOE+OO S.80E-Ol 

l.00E+04 4. 86E-08 S.58E-02 O.OOE+OO S.80E-Ol 

B-364 
CLASS Y AHAD = 1 KICRON STABLE SCANDIUK 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3. 89E-03 3.04E-OI 2. 58E-OI 7.3lE-02 6. 39E-Ol 

2.00E-Ol 3.90E-03 2. 85E-Ol 2.l7E-OI 1. 33E-Ol 6.39E-Ol 

3.00E-OI 3.90E-03 2.70E-Ol 1. 82E-Ol 1. 82E-Ol 6. 38E-Ol 

4.00E-Ol 3.90E-03 2. 57E-Ol 1.53E-Ol 2.2IE-Ol 6. 36E-Ol 

5.00E-Ol 3.90E-03 2. 47E-Ol 1. 29E-Ol 2. 52E-Ol 6. 32E-Ol 

6.00E-Ol 3.90B-03 2. 38E-Ol I.OBE-Ol 2. 76E-Ol 6.27E-Ol 

7.00E-Ol 3.90E-03 2.31E-Ol 9. 12E-02 2. 94E-Ol 6.20E-Ol 

8.00E-Ol 3.90E-03 2. 24E-Ol 7.67E-02 3.05E-Ol 6.10E-Ol 

9.00E-Ol 3.90E-03 2. 19E-0l 6. 45E-02 3.l3E-OI S.99E-Ol 

1.00E+OO 3.90E-03 2.DE-Ol 5.42E-02 3. 15E-Ol 5.B7E-Ol 

2.00E+OO 3.8BE-03 1. BOE-Ol 9.S9E-03 2. 32E-Ol 4. 26E-Ol 

3.00E+OO 3. 86E-03 1. 65E-Ol 1.70E-03 1.25E-Ol 2. 95E-:Ol 

4.00E+OO 3. 84E-03 1. 57E-OI 3.00E-04 6.07E-02 2. 22E-OI 

5.00E+OO 3.B3E-03 I.S3E-Ol 5.30E-OS 2.B6E-02 I.B5E-Ol 

6.00E+OO 3.B2E-03 1.51E-Ol 9. 37E-06 1. 34E-02 1. 68E-Ol 

7.00E+OO 3.BIE-03 1.49E-Ol 1. 66E-06 6.44E-03 1.60E-Ol 

B.OOE+OO 3. BOE-03 1. 49E-Ol 2. 93E-07 3.1BE-03 1. 56E-Ol 

9.00E+OO 3. BOE-03 1.4BE-Ol 5. 17E-OB 1.6SE-03 1. 54E-Ol 

1.00E+Ol 3.BOE-03 1.4BE-Ol O.OOE+OO 9. 21E-04 I.S3E-Ol 

2.00E+Ol 3.B7E-03 1. 46E-Ol O.OOE+OO 2.36E-04 I.SIE-Ol 

3.00E+Ol 3. 99E-03 1.45E-Ol O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+OI 4. 12E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.48E-Ol 

5.00E+Ol 4. 26E-03 1.42E-Ol O.OOE+OO 2.26E-04 1. 46E-Ol 

6.00E+Ol 4.40E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1.4SE-Ol 

7.00E+OI 4.S4E-03 1. 39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

B.OOE+OI 4.6BE-03 1.3BE-Ol O.OOE+OO 2.l7E-04 1.43E-Ol 

9.00E+OI 4. 82E-03 1. 36E-Ol O.OOE+OO 2. 14E-04 1.41E-Ol 

1.00E+02 4. 96E-03 1.3SE-Ol O.OOE+OO 2.11E-04 I.40E-Ol 

2.00E+02 6. 33E-03 1. 22E-Ol O.OOE+OO 1. 84E-04 1.28E-Ol 

3.00E+02 7. 67E-03 1.IOE-OI O.OOE+OO l.60E-04 1.18E-Ol 

4.00E+02 B.9SE-03 9. 98E-02 .O.OOE+OO 1.39E-04 1.09E-Ol 

S.OOE+02 1.02E-02 9.06E-02 O.OOE+OO 1. 21E-04 1.0IE-Ol 

6.00E+02 I.I3E-02 8. 23E-02 O.OOE+OO 1.0SE-04 9. 37E-02 

7.00E+02 1. 24E-02 7.49E-02 O.OOE+OO 9.IBE-OS B.74E-02 

8.00E+02 1.33E-02 6.B3E-02 O.OOE+OO 7. 99E-OS 8. 17E-02 

9.00E+02 1.42E-02 6. 23E-02 O.OOE+OO 6. 96E-OS 7. 66E-02 .. ,' 1.00E+03 I.S0E-02 S.70E-02 O.OOE+OO 6.06E-OS 7.2IE-02 " " 

-,,- ,. 2.00E+03 I.8SE-02 2.SSE-02 O.OOE+OO I.SIE-OS 4.40E-02 

3.00E+03 1. 69E-02 1.34E-02 O.OOE+OO 3. 79E-06 3.03E-02 

4.00E+03 1.34E-02 B.2SE-03 O.OOE+OO 9. 46E-07 2. 17E-02 

S.OOE+03 9.B9E-03 S.92E-03 O.OOE+OO 2. 37E-07 I.S8E-02 

7.00E+03 4.7SE-03 4. 27E-03 O.OOE+OO 1.4BE-OB 9.02E-03 

B.OOE+03 3.1BE-03 4.00E-03 O.OOE+OO O.OOE+OO 7.1BE-03 

9.00E+03 2.09E-03 3.B7E-03 O.OOE+OO O.OOE+OO S.96E-03 

1.00E+04 1. 37E-03 3. BOE-03 O.OOE+OO O.OOE+OO S.17E-03 

2.00E+04 I.S0E-OS 3. 74E-03 O.OOE+OO O.OOE+OO 3.7SE-03 

B-36S 
CLASS·Y AHA» = 1 MICRON STABLE SCANDIUM 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEr41C 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 4.74E-06 1.04E-05 

2.00E-Ol 1.02E-05 2.10E-04 

3.00E-Ol 1. 56E-05 1.06E-03 

4.00E-Ol 2.1OE-05 3.07E-03 

5.00E-Ol 2. 62E-05 6. 67E-03 

6.00E-Ol 3. 15E-05 1.21E-02 

7.00E-Ol 3. 66E-05 1.94E-02 

8.00E-Ol 4. 17E-05 2. 86E-02 

9.00E-Ol 4. 68E-05 3. 96E-02 

1.00E+00 5. 17E-05 5. 17E-05 5.21E-02 5.21E-02 

2.00E+00 4. 65E-05 9. 82E-05 1.61E-01 2.l3E-01 

3.00E+00 4.1OE-05 1. 39E-04 1.31E-Ol 3. 44E-Ol 

4.00E+00 3. 62E-05 1. 75E-04 7. 36E-02 4.17E-01 

5.00E+00 3. 19E-05 2.07E-04 3. 64E-02 4. 54E-Ol 

6.00E+00 2. 82E-05 2. 36E-04 1.73E-02 4.71E-01 

7.00E+00 2.50E-05 2. 61E-04 8. 13E-03 4. 79E-Ol 

8.00E+00 2. 23E-05 2. 83E-04 3.88E-03 4. 83E-Ol 

9.00E+00 1. 98E-05 ·3.03E-04 1.91E-03 4. 85E-Ol 

1.00E+Ol 1. 77E-05 3.20E-04 9.86E-04 4.86E-01 

2.00E+Ol 7.08E-06 4.27E-04 1.36E-04 4. 88E-01 

3.00E+Ol 4.47E-06 4.81E-04 1.33E-04 4.89E-Ol 

4.00E+Ol 3. 87E-06 5. 21E-04 1.31E-04 4.91E-Ol 

5.00E+Ol 3. 78E-06 5. 59E-04 1.29E-04 4. 92E-Ol 

6.00E+Ol 3. 81E-06 5. 97E-04 1. 28E-04 4.9;3E-Ol 

7.00E+Ol 3. 87E-06 6. 35E-04 1.26E-04 4. 95E-Ol 

8.00E+Ol 3. 93E-06 6. 75E-04 1. 24E-04 4. 96E-Ol 

9.00E+Ol 4.00E-06 7. 14E-04 1.22E-04 4. 97E-Ol 

1.00E+02 4.07E-06 7.55E-04· 1. 21E-04 4. 98E-Ol 

2.00E+02 4. 75E-06 1.20E-03 1.05E-04 5.10E-Ol 

3.00E+02 5. 39E-06 1.70E-03 9. 15E-05 5. 19E-Ol 

4.00E+02 5. 98E-06 2. 27E-03 7.96E-05 5. 28E-Ol 

5.00E+02 6. 52E-06 2.90E-03 6. 93E-05 5. 35E-Ol 

7.00E+02 7. 46E-06 4.30E-03 5.25E-05 5.47E-Ol 

8.00E+02 7. 86E-06 5.07E-03 4. 57E-05 5. 52E-Ol 

9.00E+02 8. 22E-06 5. 87E-03 3. 98E-05 5. 57E-Ol 

1.00E+03 8. 52E-06 . 6. 71E-03 3. 47E-05 5.60E-Ol 

2.00E+03 9. 55E-06 1.60E-02 8.66E-06 5. 79E-Ol 

3.00E+03 8. 35E-06 2. 51E-02 2. 17E-06 5. 84E-Ol 

4.00E+03 6. 49E-06 3. 25E-02 5. 42E-07 5. 85E-Ol 

5.00E+03 4. 71E-06 3. 81E-02 1. 35E-07 5. 85E-Ol 

7.00E+03 2. 23E-06 4. 48E-02 O.OOE+oo 5. 85E-Ol 

8.00E+03 1.49E-06 4. 66E-02 O.OOE+OO 5. 85E-Ol 

9.00E+03 9. 77E-07 4. 78E-02 O.OOE+OO 5. 85E-Ol 

1.00E+04 6. 35E-07 4. 86E-02 O.OOE+OO 5. 85E-Ol 

B-366 
CLASS Y AMAD = 1 MICRON STABLE TITANIUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 3. 99E-03 3.04E-OI 2.58E-OI 7.30E-02 6.39E-OI 

2.00E-OI 4.32E-03 2.85E-OI 2.17E-OI 1. 33E-OI 6.39E-OI 

3.00E-OI 4.77E-03 2.70E-OI I.82E-OI I.8IE-OI 6.3BE-OI 

4.00E-OI 5. 23E-03 2. 57E-OI 1. 53E-OI 2.20E-OI 6. 36E-OI 

S.OOE-OI 5. 67E-03 2.47E-OI I.29E-OI 2. SIE-Ol 6.32E-OI 

6.00E-OI 6.06E-03 2.38E-OI I.OBE-OI 2. 74E-OI 6.27E-OI 

7.00E-OI 6.4lE-03 2.3lE-OI 9.12E-02 2.9IE-0l 6.20E-OI 

8.00E-OI 6.7lE-03 2.24E-Ol 7.67E-02 3.03E-Ol 6.llE-OI 

9.00E-OI 6. 96E-03 2.19E-Ol 6.45E-02 3. lOE-Ol 6.00E-OI 

I.OOE+OO 7.19E-03 2.13E-OI 5. 42E-02 3.l3E-Ol 5.87E-Ol 

2.00E+OO 8.27E-03 1. BOE-Ol 9.59E-03 2.30E-OI 4.2BE-OI 

3.00E+OO 8.5BE-03 1. 65E-OI I.70E-03 1. 24E-OI 2. 99E-OI 

4.00E+OO B.70E-03 I.S7E-OI 3.00E-04 6.00E-02 2.26E-OI 

5.00E+OO B.76E-03 I.53E-OI S.30E-OS 2.B3E-02 I.90E-Ol 

6.00E+OO B.79E-03 l.5IE-Ol 9. 37E-06 I.33E-02 I.73E-OI 

7.00E+OO B.8IE-03 1.49E-OI 1. 66E-06 6.37E-03 1.6SE-OI 

B.OOE+OO 8.B2E-03 1.49E-Ol 2. 93E-07 3.14E-03 I.6IE-OI 

9.00E+OO B.84E-03 I.4BE-OI 5.17E-OB 1. 63E-03 1. 59E-OI 

I.OOE+OI B.8SE-03 I.48E-OI O.OOE+OO 9.llE-04 I.S8E-Ol 

2.00E+OI 8.93E-03 I.46E-OI O.OOE+OO 2. 34E-04 I.S6E-OI 

3.00E+Ol 9.02E-03 1. 45E-OI O.OOE+OO 2.30E-04 1.54E-OI 

4.00E+OI 9.10E-03 I.43E-Ol O.OOE+OO 2.27E-04 I.S3E-OI 

S.OOE+Ol 9.l8E-03 1.42E-OI O.OOE+OO 2.24E-04 1.5IE-Ol 

6.00E+OI 9.27E-03 I.4IE-Ol O.OOE+OO 2.2IE-04 I.50E-OI 

7.00E+OI 9.3SE-03 I.39E-OI O.OOE+OO 2.18E-04 l.49E-OI 

8.00E+Ol 9.43E-03 I. 38E-OI O.OOE+OO 2. ISE-04 I.47E-Ol 

9.00E+OI 9.5IE-03 I.36E-OI O.OOE+OO 2.l2E-04 I.46E-Ol 

I.OOE+02 9. 59E-03 1.35E-OI O.OOE+OO 2.09E-04 I.4SE-OI 

2.00E+02 I.04E-02 I.22E-OI O.OOE+OO I.82E-04 I.32E-Ol 

3.00E+02 I.llE-02 1. IDE-Ol O.OOE+OO I.S8E-04 I.2IE-OI 

4.00E+02 1.I7E-02 9. 98E-02 O.OOE+OO I.38E-04 I.12E-OI 

5.00E+02 1. 22E-02 9.06E-02 O.OOE+OO I.20E-04 I.03E-OI 

6.00E+02 1. 27E-02 8.23E-02 O.OOE+OO 'I.04E-04 9. SIE-02 

7.00E+02 I.30E-02 7.49E-02 O.OOE+OO 9.09E-05 8.80E-02 

8.00E+02 I.33E-02 6. 83E-02 O.OOE+OO 7.9IE-OS 8.16E-02 

9.00E+02 1.3SE-02 6.23E-02 O.OOE+OO 6. 89E-OS 7.S9E-02 

1.OOE+03 1.36E-02 S.70E-02 O.OOE+OO 6.00E-OS 7.06E-02 , " 

" 2.00E+03 I.16E-02 2.SSE-02 O.OOE+OO I.50E-OS 3.7IE-02 

3.00E+03 7. 84E-03 I.34E-02 O.OOE+OO 3.7SE-06 2.12E-02 

4.00E+03 4. 68E-03 8.2SE-03 O.OOE+OO 9.37E-07 1. 29E-02 

S.OOE+03 2.6lE-03 S.92E-03 O.OOE+OO 2. 34E-07 B.S3E-03 

7.00E+03 7.30E-04 4. 27E-03 O.OOE+OO 1. 46E-OB S.OOE-03 

8.00E+03 3.76E-04 4.00E-03 O.OOE+OO O.OOE+OO 4.3BE-03 

9.00E+03 1.9lE-04 3. 87E-03 O.OOE+OO O.OOE+OO 4.06E-03 

1.OOE+04 9. 67E-OS 3.80E-03 O.OOE+OO O.OOE+OO 3.90E-03 

2.00E+04 9. 63E-08 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-367 
CLASS Y AHA» = 1 MICRON STABLE TITANIUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3. 89E-07 1.04E-05 

2.00E-Ol 8.67E-07 2.10E-04 

3.00E-Ol 1.39E-06 1.05E-03 

4.00E-Ol 1.97E-06 3.06E-03 

5.00E-Ol 2.60E-06 6. 64E-03 

6.00E-Ol 3. 28E-06 1.20E-02 

7.00E-Ol 4.00E-06 1.93E-02 

8.00E-Ol 4. 75E-06 2. 85E-02 

9.00E-Ol 5. 54E-06 3. 93E-02 

1.00E+00 6.36E-06 6.36E-06 5.17E-02 5. 17E-02 

2.00E+00 9.07E-06 1. 54E-05 1.59E-Ol 2.11E-Ol 

3.00E+00 9.76E-06 2.52E-05 1.30E-Ol 3.41E-Ol 

4.00E+00 9. 99E-06 3. 52E-05 7. 28E-02 4. 13E-Ol 

5.00E+00 1.01E-05 4. 53E-05 3.60E-02 4.49E-Ol 

6.00E+00 1.01E-05 5. 54E-05 1.71E-02 4. 66E-Ol 

7.00£+00 1.02E-05 6.56E-05 8.04E-03 4. 74E-Ol 

8.00E+00 1.02E-05 7. 58E-05 3. 84E-03 4. 78E-OI 

9.00E+00 1.02E-05 8.60E-05 1. 89E-03 4.80E-Ol 

1.00E+Ol 1.02E-05 9. 62E-05 9.75E-04 4.81E-Ol 

2.00E+Ol 1.03E-05 1.99E-04 1. 34E-04 4.83E-Ol 

3.00E+Ol 1.04E-05 3.02E-04 1.32E-04 4.85E-Ol 

4.00E+Ol 1.05E-05 4.07E-04 1.30E-04 4.86E-Ol 

5.00E+Ol 1.06E-05 5. 13E-04 1. 28E-04 4.87E-Ol 

6.00E+Ol 1.07E-05 6. 19E-04 1.26E-04 4.88E-Ol 

7.00E+Ol 1.08E-05 7.27E-04 1.25E-04 4.90E-Ol 

8.00E+Ol 1.09E-05 8. 35E-04 1.23E-04 4.91E-Ol 

9.00E+Ol l.lOE-05 9.45E-04 1.21E-04 4. 92E-Ol 

1.00E+02 1. 11E-05 1.05E-03 1.19E-04 4. 93E-Ol 

2.00E+02 1.20E-05 2.21E-03 1.04E-04 5.05E-Ol 

3.00£+02 1.28E-05 3.45E-03 9.06E-05 5. 14E-Ol 

4.00E+02 1.35E-05 4. 76E-03 7.88E-05 5.23E-Ol 

5.00E+02 1.41E-05 6.15E-03 6.86E-05 5.30E-Ol 

7.00E+02 1.50E-05 9.07E-03 5.20E-05 5.42E-Ol 

8.00£+02 I.53E-05 1.06E-02 4. 53E-05 5.47E-Ol 

9.00E+02 1. 55E-05 1.2IE-02 3.94E-05 5.51E-Ol 

1.00E+03 1.57E-05 1.37E-02 3.43E-05 5. 55E-OI 

2.00E+03 1.34E-05 2. 86E-02 8. 58E-06 5. 73E-Ol 

3.00E+03 9.06E-06 3. 99E-02 2. 14E-06 5.78E-Ol 

4.00E+03 5.41E-06 4.70E-02 5. 36E-07 5. 79E-Ol 

5.00E+03 3.02E-06 5. 12E-02 1.34E-07 5. 79E-Ol 

7.00£+03 8.44E-07 5.46E-02 O.OOE+OO 5.80E-Ol 

8.00E+03 4. 34E-07 5. 52E-02 O.OOE+OO 5.80E-Ol 

9.00E+03 2.21E-07 5. 55E-02 O.OOE+OO 5.80E-OI 

1.00E+04 1. 12E-07 5.57E-02 O.OOE+OO 5.80E-Ol 

B-368 
CLASS Y AMAD = 1 MICRON BALFLIFE= 2.77E+01 DAYS CHROMIUM .51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 4.76E-03 3.03E-Ol 2. S7E-Ol 7.18E-02 6.37E-Ol 

2.00E-OI 7.93E-03 2.84E-Ol 2.l6E-Ol 1. 28E-OI 6.3SE-OI 

3.00E-OI I.21E-02 2. 68E-Ol 1.8IE-0l I.7IE-OI 6.32E-OI 

4.00E-OI I.6IE-02 2.SSE-OI I.S2E-OI 2.06E-OI 6. 28E-OI 

S.OOE-OI I.97E-02 2.44E-OI l.27E-OI 2. 32E-OI 6.23E-OI 

6.00E-OI 2.28E-02 2.3SE-OI I.07E-OI 2.SIE-OI 6.ISE-OI 

7.00E-Ol 2.S2E-02 2.27E-OI B.97E-02 2.6SE-Ol 6.06E-OI 

8.00E-Ol 2.7IE-02 2.20E-OI 7.S2E-02 2. 73E-Ol S.9SE-OI 

9.00E-Ol 2.B6E-02 2. 14E-OI 6.3IE-02 2. 78E-OI 5.B3E-Ol 

I.OOE+OO 2.97E-02 2.0BE-OI S.29E-02 2. 79E-Ol S.70E-OI 

2.00E+OO 3.16E-02 1.72E-OI 9.12E-03 1.97E-OI 4.IOE-OI 

3.00E+OO 2. 94E-02 I.S3E-OI I.S7E-03 1.03E-OI 2.87E-OI 

4.00E+OO 2.7IE-02 I.42E-OI 2.71E-04 4. B8E-02 2.18~-OI 

S.OOE+OO 2.S0E-02 I.3SE-OI 4.67E-05 2. 24E-02 1. 82E-Ol 

6.00E+OO 2.3IE-02 I.30E-OI 8.06E-06 I.03E-02 I.63E-OI 

7.00E+OO 2.I4E-02 I.2SE-OI 1. 39E-06 4.80E-03 I.S2E-OI 

8.00E+OO I.99E-02 I.22E-OI 2.40E-07 2.3IE-03 I.44E-OI 

9.00E+OO l.BSE-02 1.IBE-Ol 4.13E-OB l.I7E-03 I.3BE .... Ol 

l.OOE+Ol 1. 73E-02 l.I5E-OI O.OOE+OO 6. 39E-04 I.33E-OI 

2.00E+Ol 9.87E-03 B.BBE-02 O.OOE+OO I.29E-04 9.BBE-02 

3.00E+Ol 6.S4E-03 6.B4E-02 O.OOE+OO 9.90E-OS 7.SIE-02 

4.00E+OI 4.62E-03 S.27E-02 O.OOE+OO 7.60E-OS S.74E-02 

S.OOE+Ol 3. 34E-03 4.06E-02 O.OOE+OO S.84E-OS 4.40E-02 

6.00E+OI 2.44E-03 3.13E-02 O.OOE+OO 4.4BE-OS 3.3BE-02 

7.00E+OI 1. 79E-03 2.4IE-02 O.OOE+OO 3. 44E-OS 2.60E-02 

8.00E+OI 1. 32E-03 I.B6E-02 O.OOE+OO 2.64E-05 I.99E-02 

9.00E+OI 9. 73E-04 I.43E-02 O.OOE+OO 2.03E-OS I.S3E-02 

I.OOE+02 7.I9E-04 1. IOE-02 O.OOE+OO 1. 56E-05 I.IBE-02 

2.00E+02 3.B4E-05 B.17E-04 O.OOE+OO 1. llE-06 B.S7E-04 

3.00E+02 2.4lE-06 6.06E-OS O.OOE+OO 7. 93E-OB 6.3IE-OS 

4.00E+02 I.70E-07 4.S0E-06 O.OOE+OO O.OOE+OO 4.67E-06 

S.OOE+02 I.2BE-OB 3. 34E-07 O.OOE+OO O.OOE+OO 3.47E-07 

B-369 
CLASS Y AMAD == 1 MICRON HALFLIFE= 2.77E+OI DAYS CHROMIUM 51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR Ace illlULATED 24-HOUR ACCUHULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.60E-04 1.03E-05 

2.00E-01 4. 25E-04 2.05E-04 

3.00E-01 8.39E-04 1.02E-03 

4.00E-01 1.41E-03 2.93E-03 

5.00E-01 2.10E-03 6.29E-03 

6.00E-Ol 2.90E-03 1.13E-02 

7.00E-01 3. 76E-03 1.80E-02 

8.00E-Ol 4.65E-03 2.64E-02 

9.00E-01 5. 55E-03 3.62E-02 

1.00E+00 6.45E-03 6.45E-03 . 4.73E-02 4.73E-02 

2.00E+00 7.33E-03 1.36E-02 1.38E-01 1.85E-01 

3.00E+00 4.22E-03 1. 75E-02 1.09E-01 2.89E-01 

4.00E+00 2.60E-03 1.97E-02 5.93E-02 3.41E-01 

5.00E+00 1.86E-03 2.10E-02 2.85E-02 3.61E-01 

6.00E+00 1.48E-03 2.20E-02 1.32E-02 3.65E-01 

7.00E+00 1.24E-03 2.27E-02 6.05E-03 3.62E-01 

8.00E+00 1.06E-03 2.32E-02 2. 82E-03 3.56E-01 

9.00E+00 9.22E-04 2.35E-02 1.36E-03 3.49E-01 

1.00E+01 8.07E-04 2.38E-02 6.83E-04 3.41E-01 

2.00E+01 2.45E-04 2.23E-02 7.40E-05 2.66E-01 

3.00E+01 9.54E-05 1.87E-02 5. 65E-05 2.08E-01 

4.00E+Ol 4. 95E-05 1.51E-02 4.34E-05 1.62E-01 

5.00E+Ol 3. 12E-05 1. 21E-02 3. 33E-05 1. 27E-Ol 

6.00E+01 2.17E-05 9. 66E-03 2.56E-05 9.90E-02 

7.00E+01 1.56E-05 7. 68E-03 1.97E-05 7.73E-02 

8.00E+Ol 1.14E-05 6.10E-03 1.51E-05 6.03E-02 

9.00E+01 8.40E-06 4.84E-03 1.16E-05 4.71E-02 

1.00E+02 6.19E-06 3.83E-03 8.90E-06 3.67E-02 

2.00E+02 3.25E-07 3.54E-04 6. 35E-07 3.08E-03 

3.00E+02 2.00E-08 3.13E-05 4. 53E-08 2.57E-04 

B-370 
CLASS Y AMAD = 1 MICRON STABLE CHROMIUM 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 4.77E-03 3.04E-Ol 2.SBE-Ol 7.20E-02 6. 39E-Ol 

2.00E-Ol 7.97E-03 2. BSE-OI 2.17E-Ol l.2BE-OI 6.3BE-OI 

3.00E-OI 1.2lE-02 2.70E-Ol 1. B2E-Ol I. 73E-Ol 6. 37E-OI 

4.00E-OI 1.63E-02 2.S7E-Ol 1. S3E-Ol 2.0BE-OI 6.3SE-OI 

S.OOE-OI 2.00E-02 2.47E-OI I.29E-Ol 2. 34E-Ol 6.3IE-OI 

6.00E-OI 2.3lE-02 2.3BE-OI 1.0BE-OI 2.SSE-Ol 6.2SE-OI 

7.00E-OI 2.S6E-02 2.3IE-OI 9.12E-02 2. 69E-Ol 6.17E-0l 

B.OOE-Ol 2.77E-02 2. 24E-Ol 7. 67E-02 2. 79E-OI 6.07E-Ol 

9.00E-OI 2.92E-02 2.19E-OI 6.4SE-02 2.B4E-OI 5. 96E-OI 

1.00E+OO 3.04E-02 2. 13E-OI S.42E-02 2.B6E-Ol 5.B4E-OI 

2.00E+OO 3. 32E-02 I. BOE-Ol 9.S9E-03 2.0BE-OI 4.3lE-OI 

3.00E+OO 3.17E-02 1.6SE-Ol 1.70E-03 I.llE-Ol 3.09E-OI 

I 4.00E+OO 2.99E-02 1. S7E-OI 3.00E-04 S.39E-02 2.4IE-OI 

5.00E+OO 2.B3E-02 I.S3E-OI 5.30E-OS 2.S4E-02 2.06E-OI 

6.00E+OO 2. 69E-02 I.SIE-OI 9.37E-06 I.I9E-02 I. B9E-0l 

7.00E+OO 2.SSE-02 1.49E-Ol I.66E-06 S.72E-03 I.BIE-OI 

B.OOE+OO 2.43E-02 I.49E-Ol 2. 93E-07 2.B3E-03 1. 76E-Ol 

9.00E+OO 2.32E-02 I.4BE-OI S.17E-OB I.47E-03 1. 73E-Ol 

I.OOE+OI 2.22E-02 I.4BE-Ol O.OOE+OO B.21E-04 1.7IE-OI 

2.00E+OI I. 63E-02 1.46E-Ol O.OOE+OO 2.13E-04 1. 63E-Ol 

3.00E+Ol 1.3BE-02 1.4SE-OI O.OOE+OO 2.IOE-04 I.S9E-OI 

4.00E+OI 1.26E-02 I.43E-OI O.OOE+OO 2.07E-04 I.S6E-Ol 

S.OOE+OI I.17E-02 I.42E-Ol O.OOE+OO 2.04E-04 1. 54E-OI 

6.00E+Ol 1. IOE-02 I.4IE-OI O.OOE+OO 2.0IE-04 I.S2E-Ol 

7.00E+OI I.03E-02 1.39E-0l O.OOE+OO I.9BE-04 1. SOE-OI 

B.OOE+OI 9.77E-03 1. 38E-OI O.OOE+OO 1. 96E-04 1.48E-OI 

9.00E+OI 9.2SE-03 1.36E-OI O.OOE+OO 1.93E-04 I.46E-OI 

I.OOE+02 8.78E-03 I.3SE-Ol O.OOE+OO I.90E-04 I.44E-OI 

2.00E+02 5.7IE-03 I.22E-Ol O.OOE+OO 1. 66E-04 1.28E-OI 

3.00E+02 4. 38E-03 1. IOE-Ol O.OOE+OO I.44E-04 1. ISE-OI 

4.00E+02 3.77E-03 9. 98E-02 O.OOE+OO I.26E-04 1.04E-OI 

S.OOE+02 3. 47E-03 9.06E-02 O.OOE+OO I.09E-04 9.4IE-02 

6.00E+02 3. 29E-03 8. 23E-02 O.OOE+OO 9.S2E-OS 8.S7E-02 

7.00E+02 3. 17E-03 7. 49E-02 O.OOE+OO 8.2BE-OS 7. 82E-02 

8.00E+02 3.06E-03 6.B3E-02 O.OOE+OO 7.2IE-OS 7.14E-02 

9.00E+02 2. 96E-03 6. 23E-02 O.OOE+OO 6. 28E-OS 6.S4E-02 

I.OOE+03 2. 87E-03 S.70E-02 O.OOE+OO S.47E-OS S.99E-02 

2.00E+03 1. 98E-03 2.SSE-02 O.OOE+OO 1. 37E-OS 2.7SE-02 

3.00E+03 I. 28E-03 1. 34E-02 O.OOE+OO 3. 42E-06 I.47E-02 

4.00E+03 7.8IE-04 8.2SE-03 O.OOE+OO 8.S4E-07 9.03E-03 

S.OOE+03 4. 63E-04 S.92E-03 O.OOE+OO 2.I4E-07 6.3BE-03 

7.00E+03 I.S2E-04 4. 27E-03 O.OOE+OO 1. 33E-08 4. 42E-03 

8.00E+03 8.S2E-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.09E-03 

9.00E+03 4.7IE-OS 3. 87E-03 O.OOE+OO O.OOE+OO 3. 92E-03 

I.OOE+04 2.S9E-OS 3. BOE-03 O.OOE+OO O.OOE+OO 3. 83E-03 

2.00E+04 4.7SE-08 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-371 
CLASS Y AMAD = 1 MICRON STABLE CHROMIUM 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 1.60E-04 I.03E-OS 

2.00E-OI 4.27E-04 2.06E-04 

3.00E-OI 8.4SE-04 I.03E-03 

4.00E-OI l.42E-03 2. 96E-03 

5.00E-OI 2.13E-03 6. 37E-03 

6.00E-OI 2. 94E-03 1.15E-02 

7.00E-Ol 3. 82E-03 1.83E-02 

S.OOE-Ol 4. 74E-03 2. 69E-02 

9.00E-OI S.68E-03 3.70E-02 

1.00E+OO 6.6IE-03 6.61E-03 4.SSE-02 4.SSE-02 

2.00E+OO 7.7IE-03 1.43E-02 1.46E-OI I.94E-OI 

3.00E+OO 4. 55E-03 1. 89E-02 1.17E-01 3. l1E-01 

4.00E+OO 2.S7E-03 2.17E-02 6.SSE-02 3.77E-01 

S.OOE+OO 2.1IE-03 2. 38E-02 3. 23E-02 4.09E-OI 

6.00E+OO I.72E-03 2. 56E-02 1. 53E-02 4.24E-01 

7.00E+OO I.47E-03 2.70E-02 7.2IE-03 4.3IE-OI 

8.00E+OO I.30E-03 2. 83E-02 3. 45E-03 4. 35E-OI 

9.00E+OO 1. 16E-03 2. 95E-02 I.70E-03 4. 37E-OI 

1.00E+Ol 1.04E-03 3.0SE-02 8.77E-04 4.37E-Ol 

2.00E+01 4.03E-04 3.6SE-02 1.22E-04 4.39E-Ol 

3.00E+OI 2.02E-04 3. 95E-02 1.20E-04 4.41E-OI 

4.00E+OI I.35E-04 4.IIE-02 1. 18E-04 4.42E-OI 

5.00E+OI I.09E-04 4. 23E-02 I.16E-04 4.43E-Ol 

6.00E+Ol 9. 74E-05 4.33E-02 I.I5E-04 4.44E-OI 

7.00E+Ol 9.0IE-OS 4. 43E-02 1. 13E-04 4.45E-OI 

8.00E+Ol 8.46E-05 4. 52E-02 1. 12E-04 4.46E-OI 

9.00E+OI 7.99E-05 4.60E-02 1. IOE-04 4.47E-Ol 

1.00E+02 7.56E-05 4. 67E-02 I.09E-04 4.49E-OI 

2.00E+02 4.S4E-05 5.27E-02 9. 46E-05 4.59E-OI 

3.00E+02 3. 63E-OS S.69E-02 8. 23E-OS 4.6SE-OI 

4.00E+02 3.06E-05 6.02E-02 7.17E-05 4. 75E-OI 

S.OOE+02 2. 74E-OS 6.3IE-02 6.24E-05 4.82E-Ol 

7.00E+02 2.40E-OS 6.S2E-02 4.73E-OS 4.93E-OI 

8.00E+02 2.27E-OS 7.0SE-02 4. 12E-05 4. 97E-Ol 

; .. " 9.00E+02 2. 15E-OS 7.27E-02 3.5SE-OS S.OIE-OI ,.; ' .. ;, I.OOE+03 2.04E-OS 7.4SE-02 3.12E-OS S.04E-OI 

2.00E+03 1.ISE-05 9.04E-02 7.80E-06 S.2IE-OI 

3.00E+03 6.19E-06 9.90E-02 l.95E-06 5.2SE-Ol 

4.00E+03 3.2SE-06 I.04E-Ol 4.87E-07 5.27E-Ol 

S.OOE+03 1. 69E-06 I.06E-Ol 1.22E-07 5.27E-OI 

7.00E+03 4.S1E-07 I.08E-Ol O.OOE+OO S.27E-OI 

8.00E+03 2.32E-07 I.08E-Ol O.OOE+OO S.27E-Ol 

9.00E+03 I.I9E-07 I.08E-OI O.OOE+OO S.27E-OI 

I.OOE+04 6.l2E-08 I.08E-Ol O.OOE+OO S.27E-OI 

B-372 
CLASS Y AHAD - 1 MICRON HALFLlFE- 7.08£+01 DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYS'£EMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 4.lSE-03 3.04E-OI 2. SSE-OI 7.2SE-02 6.3SE-OI 

2.00E-Ol S.49E-03 2.SSE-Ol 2.17E-OI ' I.3IE-Ol 6. 37E-OI 

3.00E-OI 7.3lE-03 2. 69E-OI I.82E-Ol 1. 77E-Ol 6.3SE-OI 

4.00E-OI 9. IOE-03 2.S6E-Ol 1.S3E-OI 2.14E-OI 6. 32E-OI 

S.OOE-Ol 1.07E-02 2. 46E-0l I.28E-OI 2. 42E-Ol 6.27E-Ol 

6.00E-Ol I.19E-02 2. 37E-Ol 1.08E-OI 2. 64E-Ol 6.2IE-OI 

7.00E-Ol 1.29E-02 2.29E-OI 9.06E-02 2.80E-OI 6.12E-Ol 

8.00E-Ol 1. 36E-02 2. 23E-OI 7.6IE-02 2.90E-OI 6.02E-OI 

9.00E-OI 1.4IE-02 2.l7E-OI 6.39E-02 2. 96E-Ol S.9IE-Ol 

I.OOE+OO I.44E-02 2.11E-OI S.37E-02 2. 98E-Ol S.77E-OI 

2.00E+OO 1. 38E-02 I.77E-OI 9.40E-03 2.l6E-OI 4.16E-OI 

3.00E+OO 1.22E-02 I.60E-OI I.6SE-03 1.lSE-OI 2.S8E-OI 

4.00E+OO 1.llE-02 1. SlE-Ol 2. 88E-04 S.SIE-02 2.l7E-OI 

S.OOE+OO 1.03E-02 I.4SE-OI S.04E-OS 2.S7E-02 1.8IE-OI 

6.00E+OO 9. 63E-03 1. 42E-OI 8.83E-06 1.20E-02 I.64E-0l 

7.00E+OO 9.03E-03 I.40E-OI 1.SSE-06 S.67E-03 1.S4E-Ol 

8.00E+OO 8. 49E-:,03 I.38E-0l 2.71E-07 2.78E-03 I.49E-OI 

9.00E+OO 8.02E-03 1.36E-OI 4. 74E-08 1. 43E-03 I.4SE-OI 

I.OOE+OI 7.S9E-03 1. 34E-Ol O.OOE+OO 7.89E-04 I.43E-OI 

2.00E+OI S.02E-03 I.20E-OI O.OOE+OO I.8SE-04 I.26E-OI 

3.00E+OI 3.91E-03 I.OSE-Ol O.OOE+OO 1.6SE-04 I.12E-Ol 

4.00E+Ol 3.2SE-03 9.70E-02 O.OOE+OO 1. 47E-04 1.00E-OI 

S.OOE+OI 2. 82E-03 8.70E-02 O.OOE+OO 1.32E-04 9.00E-02 

6.00E+OI 2.46E-03 7.81E-02 O.OOE+OO 1.18E-04 S.07E-02 

7.00E+Ol 2.ISE-03 7.01E-02 O.OOE+OO 1.0SE-04 7.23E-02 

8.00E+OI I.89E-03 6. 29E-02 O.OOE+OO 9.43E-OS 6. 49E-02 

9.00E+Ol I. 67E-03 S.6SE-02 O.OOE+OO 8. 43E-OS S.82E-02 

1.OOE+02 1. 47E-03 S.07E-02 O.OOE+OO 7. 54E-OS S.22E-02 

2.00E+02 4.72E-04 1.72E-02 O.OOE+OO 2.47E-05 1. 77E-02 

3.00E+02 I. 67E-04 5. 84E-03 O.OOE+OO 8.06E-06 6.02E-03 

4.00E+02 6.13E-05 1.99E-03 O.OOE+OO 2. 64E-06 2.05E-03 

5.00E+02 2.27E-05 6. 78E-04 O.OOE+OO 8. 62E-07 7.0IE-04 

6.00E+02 S.42E-06 2.31E-04 O.OOE+OO 2. 82E-07 2.40E-04 

7.00E+02 3.12E-06 7.9IE-05 O.OOE+OO 9. 22E-08 8.23E-05 

8.00E+02 1.15E-06 2.7IE-05 O.OOE+OO 3.02E-OS 2. 83E-05 

9.00E+02 4.26E-07 9.29E-06 O.OOE+OO O.OOE+OO 9.72E-06 ~." '", '. .'- 1.00E+03 1.57E-07 3. 19E-06 O.OOE+OO O.OOE+OO 3. 35E-06 ... 

'" 

B-373 
CLASS Y AHAD = 1 MICRON BALFLIFE= 7.08E+OI DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUHULATED 24-HOUR 

DAYS URINE URINE FECES 

1.00E-Ol 1. 92E-04 5. 84E-05 

2.00E-01 4. 51E-04 3.20E-04 

3.00E-01 7. 88E-04 1. 24E-03 

4.00E-01 1.21E-03 3.31E-03 

5.00E-01 1.70E-03 6. 92E-03 

6.00E-01 2. 25E-03 1. 23E-02 

7.00E-01 2. 83E-03 1. 95E-02 

8.00E-01 3. 42E-03 2. 84E-02 

9.00E-Ol 4.01E-03 3.90E-02 

1.00E+00 4.60E-03 4.60E-03 5.10E-02 5.10E-02 

2.00E+00 4. 56E-03 9.11E-03 1.51E-01 2.02E-01 

3.00E+00 2. 33E-03 1. 14E-02 1.21E-Ol 3. 21E-01 

4.00E+00 1. 23E-03 1.25E-02 6.72E-02 3. 85E-01 

5.00E+00 7. 79E-04 1.31E-02 3. 29E-02 4. 14E-01 

6.00E+00 5. 74E-04 1. 36E-02 1.55E-02 4. 26E-01 

7.00E+00 4. 65E-04 1. 39E-02 7. 28E-03 4. 29E-01 

8.00E+00 3. 95E-04 1. 42E-02 3. 49E-03 4.28E-01 

9.00E+00 3. 44E-04 1. 44E-02 1. 74E-03 4. 26E-01 

1.00E+Ol 3.03E-04 1.45E-02 9.20E-04 4. 22E-01 

2.00E+01 1.06E-04 1. 48E-02 1. 32E-04 3.85E-01 

3.00E+01 4. 84E-05 1.41E-02 1.06E-04 3.50E-OJ 

4.00E+Ol 2. 95E-05 1.31E-02 9. 16E-05 3. 18E-01 

5.00E+01 2.20E-05 1. 22E-02 8.08E-05 2.90E-01 

6.00E+01 1.80E-05 1. 12E-02 7. 19E-05 2. 63E-01 

7.00E+01 1. 54E-05 1.03E-02 6.41E-05 2.39E-01 

8.00E+01 1. 33E-05 9.49E-03 5. 72E-05 2. 18E-01 

9.00E+01 1. 16E-05 8.73E-03 5.llE-05 1.98E-0l 

1.00E+02 1.01E-05 8.02E-03 4. 56E-05 1.80E-01 

2.00E+02 3.02E-06 3. 34E-03 1.48E-05 6.92E-02 

3.00E+02 1.03E-06 1. 36E-03 4. 86E-06 2. 65E-02 

4.00E+02 3. 66E-07 5.50E-04 1.60E-06 1.01E-02 

5.00E+02 1. 33E-07 2.20E-04 5. 26E-07 3. 86E-03 

6.00E+02 4.81E-08 8. 76E-05 1. 73E-07 1.47E-03 

7.00E+02 1. 74E-08 3. 47E-05 5.71E-08 5. 58E-04 

B-374 
CLASS Y AH.AD = 1 MICRON STABLE COBALT 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 4.15E-03 3.04E-0l 2.58E-0l 7. 26E-02 6.39E-Ol 

2.00E-OI 5.50E-03 2. 85E-Ol 2.17E-OI 1.3IE-OI 6. 38E-Ol 

3.00E-OI 7. 33E-03 2.70E-Ol 1.82E-Ol 1.77E-Ol 6.37E-OI 

4.00E-OI 9. 13E-03 2.57E-01 1. 53E-OI 2.ISE-Ol 6.3SE-01 

5.00E-01 1.07E-02 2. 47E-Ol 1.29E-OI 2. 44E-OI 6.30E-Ol 

6.00E-01 1.20E-02 2.3BE-01 1.0BE-Ol 2.66E-Ol 6.2SE-OI 

7.00E-01 1.30E-02 2.31E-0l 9. 12E-02 2.B2E-01 6.l7E-Ol 

B.OOE-O! 1.37E-02 2.24E-OI 7.67E-02 2. 92E-01 6.07E-01 

9.00E-01 1.42E-02 2.19E-OI 6. 45E-02 2.9BE-Ol 5.96E-OI 

I.OOE+OO 1.46E-02 2.DE-Ol S.42E-02 3.0IE-OI 5.B3E-OI 

2.00E+OO 1.4IE-02 I.BOE-OI 9. S9E-03 2.20E-Ol 4. 24E-OI 

3.00E+OO 1.26E-02 1.65E-01 1.70E-03 1.IBE-Ol 2. 97E-Ol 

I 4.00E+OO 1. 16E-02 1.57E-Ol 3.00E-04 5.73E-02 2. 26E-OI 

5.00E+OO 1.08E-02 1. S3E-01 5.30E-05 2.70E-02 1.90E-Ol 

6.00E+OO 1.02E-02 1.5IE-OI 9.37E-06 1. 27E-02 1.73E-OI 

7.00E+OO 9.67E-03 1. 49E-OI 1. 66E-06 6.0BE-03 I.65E-01 

B.OOE+OO 9. 19E-03 1.49E-01 2.93E-07 3.00E-03 1.61E-01 

9.00E+OO 8. 76E-03 1.48E-01 S.l7E-OB I.56E-03 1. 59E-Ol 

1.00E+Ol 8. 37E-03 1.4BE-01 O.OOE+OO B.7lE-04 1.57E-Ol 

2.00E+Ol 6.11E-03 1. 46E-Ol O.OOE+OO 2. 25E-04 1. 53E-Ol 

3.00E+Ol S.2SE-03 1.45E-01 O.OOE+OO 2.21E-04 I.50E-Ol 

4.00E+Ol 4. BS E.,....O 3 1.43E-OI O.OOE+OO 2.1BE-04 1. 49E-Ol 

5.00E+Ol 4.60E-03 1.42E-Ol O.OOE+OO 2.15E-04 1.47E-Ol 

6.00E+Ol 4. 42E-03 1.4lE-Ol O.OOE+OO 2.l2E-04 1.4SE-OI 

7.00E+01 4.27E-03 1.39E-Ol O.OOE+OO 2.09E-04 1.44E-OI 

B.OOE+01 4. 14E-03 1.3BE-Ol O.OOE+OO 2.06E-04 1. 42E-Ol 

9.00E+Ol 4.02E-03 1.36E-Ol O.OOE+OO 2.03E-04 1.40E-Ol 

1.00E+02 3. 92E-03 1. 35E-Ol O.OOE+OO 2.01E-04 1.39E-OI 

2.00E+02 3. 35E-03 1.22E-Ol O.OOE+OO 1. 75E-04 1. 25E-Ol 

3.00E+02 3.l5E-03 1.lOE-Ol O.OOE+OO 1.52E-04 1.13E-Ol 

4.00E+02 3.0BE-03 9.9BE-02 O.OOE+OO I.32E-04 1.03E-01 

5.00E+02 3.03E-03 9.06E-02 O.OOE+OO 1. 15E-04 9. 37E-02 

6.00E+02 2. 99E-03 B.23E-02 O.OOE+OO 1.00E-04 8.S4E-02 

7.00E+02 2.9SE-03 7.49E-02 O.OOE+OO B.73E-05 7. 79E-02 

8.00E+02 2.9lE-03 6.B3E-02 O.OOE+OO 7.60E-05 7.l3E-02 

9.00E+02 2.B6E-03 6. 23E-02 O.OOE+OO 6.62E-05 6. 53E-02 

1.OOE+03 2. BOE-03 5.70E-02 O.OOE+OO 5. 76E-05 5.99E-02 

2.00E+03 2.lDE-03 2. 55E-02 O.OOE+OO 1. 44E-05 2. 76E-02 

3.00E+03 1. 39E-03 1.34E-02 O.OOE+OO 3.60E-06 1.48E-02 

4.00E+03 B.46E-04 8.2SE-03 O.OOE+OO 9.00E-07 9.lDE-03 

5.00E+03 4.90E-04 5.92E-03 O.OOE+OO 2.2SE-07 6.4IE-03 

7.00E+03 1. 49E-04 4.27E-03 O.OOE+OO 1.4lE-OB 4. 42E-03 

8.00E+03 7.97E-05 4.00E-03 O.OOE+OO O.OOE+OO 4.0BE-03 

9.00E+03 4.2lE-05 3.87E-03 O.OOE+OO O.OOE+OO 3.91E-03 

1.OOE+04 2.20E-05 3.80E-03 O.OOE+OO O.OOE+OO 3. 82E-03 

2.00E+04 2. 54E-08 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-375 
CLASS Y AMAD = 1 MICRON S'J'ABLE COBALT 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATE 

DAYS URINE URINE FECES FECES 

I.OOE-OI I.92E-04 5.S5E-05 

2.00E-OI 4.52E-04 3.2IE-04 

3.00E-OI 7.90E-04 I.24E-03 

4.00E-OI I.2IE-03 3. 32E-03 

5.00E-OI I.7IE-03 6. 95E-03 

6.00E-OI 2. 26E-03 1. 24E-02 

7.00E-Ol 2.S5E-03 1. 96E-02 

8.00E-OI 3.45E-03 2.S6E-02 

9.00E-OI 4.05E-03 3. 93E-02 

I.OOE+OO 4. 65E-03 4. 65E-03 5.I5E-02 5. 15E-02 

2.00E+OO 4.65E-03 9.29E-03 1.54E-01 2.06E-01 

3.00E+OO 2.40E-03 1.17E-02 1.25E-Ol 3.30E-01 

4.00E+OO 1.28E-03 I.30E-02 6.99E-02 4.00E-01 

5.00E+OO S.18E-04 1.3SE-02 3. 46E-02 4. 35E-OI 

6.00E+OO 6.09E-04 I.44E-02 1.64E-02 4.51E-01 

7.00E+OO 4. 98E-04 I.49E-02 7. 79E-03 4. 59E-Ol 

8.00E+OO 4. 27E-04 1.53E-02 3.77E-03 4~63E-OI 

9.00E+OO 3. 75E-04 1.57E-02 1.90E-03 4. 65E-Ol 

I.OOE+OI 3. 34E-04 1.60E-02 1.0IE-03 4.66E-Ol 

2.00E+OI I.29E-04 1.80E-02 1.6IE-04 4. 68E-01 

3.00E+Ol 6.50E-05 I.89E-02 1.43E-04 4.70E-01 

4.00E+OI 4.37E-05 1. 94E-02 1. 36E-04 4.71E-01 

5.00E+OI 3. 59E-05 1.9SE-02 1.32E-04 4. 72E-OI 

6.00E+01 3. 24E-05 2.02E-02 1. 29E-04 4. 74E-OI 

7.00E+Ol 3.05E-05 2.05E-02 I.27E-04 4. 75E-01 

8.00E+01 2.9IE-05 2.0SE-02 1. 25E-04 4. 76E-01 

9.00E+OI 2. 79E-05 2. llE-02 1.23E-04 4. 78E-01 

l.OOE+02 2.70E-05 2.13E-02 I.2IE-04 4. 79E-OI 

2.00E+02 2.I4E-05 2. 37E-02 I.05E-04 4.90E-Ol 

3.00E+02 1. 94E-05 2. 57E-02 9. 17E-05 5.00E-OI 

4.00E+02 I.84E-05 2.76E-02 8.02E-05 5.08E-Ol 

5.00E+02 I.77E-05 2. 94E-02 7.03E-05 5.I6E-01 

6.00E+02 I.7lE-OS 3.l1E-02 6.I6E-05 5.23E-01 

7.00E+02 I.6SE-05 3. 28E-02 S.40E-05 S.28E-01 

8.00E+02 I.S9E-OS 3.44E-02 4. 74E-05 S.33E-OI 

9.00E+02 l.53E-OS 3.60E-02 4.l6E-05 S.38E-Ol 

.' .'. I.OOE+03 I.46E-OS 3.7SE-02 3.66E-OS S.42E-Ol 

2.00E+03 8.8lE-06 4.91E-02 1.04E-OS 5. 62E-01 

3.00E+03 4. 89E-06 S. S8E-02 3. 28E-06 S.69E-01 

4.00E+03 2. 62E-06 5. 94E-02 l.I7E-06 S.71E-OI 

S.OOE+03 I.37E-06 6. 13E-02 4.7IE-07 S.7IE-OI 

6.00E+03 7.09E-07 6.24E-02 2.09E-07 S.72E-01 

7.00E+03 3. 64E-07 6. 29E-02 9.91E-08 5.72E-OI 

8.00E+03 1.86E-07 6. 31E-02 4.8SE-08 S.72E-01 

9.00E+03 9.4SE-08 6.33E-02 2.41E-08 S.72E-Ol 

1.00E+04 4. 79E-08 6. 33E-02 I.21E-08 S.72E-01 

B-376 
CLASS Y AM.AD = 1 MICRON HALFLIFE= 1.92£+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 4. 15E-03 3.04E-Ol 2. 58E-Ol 7.26E-02 6.39E-Ol 

2.00E-Ol 5.50E-03 2. 85E-Ol 2.17E-Ol . 1.31E-Ol 6. 38E-Ol 

3.00E-Ol 7.33E-03 2.70E-Ol 1.82E-Ol 1.77E-Ol 6.37E-Ol 

4.00E-Ol 9. 13E-03 2.57E-Ol 1. 53E-Ol 2. 15E-Ol 6.34E-Ol 

5.00E-Ol 1.07E-0'2 2.47E-Ol 1.29E-Ol 2.44E-Ol 6.30E-Ol 

6.00E-Ol 1.20E-02 2. 38E-Ol 1.08E-Ol 2. 66E-Ol 6.24E-Ol 

7.00E-Ol 1.30£-02 2.31E-Ol 9. 12E-02 2.81E-01 6.17E-Ol 

8.00E-Ol 1.37E-02 2. 24E-Ol 7. 67E-02 2. 92E-Ol 6.07E-Ol 

9.00E-Ol 1.42E-02 2. 18E-Ol 6.45E-02 2. 98E-Ol 5.96E-Ol 

1.00E+00 1.46E-02 2. 13E-Ol 5.42E-02 3.01E-Ol 5.83E-Ol 

2.00E+00 1.41E-02 1.80E-Ol 9. 58E-03 2.20E-Ol 4.24E-Ol 

3.00E+00 1.26E-02 1. 64E-Ol 1. 69E-03 1. 18E-Ol 2.97E-Ol 

4.00E+00 1. 16E-02 1. 56E-Ol 2.99E-04 5.72E-02 2.26E-Ol 

5.00E+00 1.08E-02 1.52E-Ol 5. 29E-05 2. 69E-02 1.90E-Ol 

6.00E+00 1.02E-02 1.50E-Ol 9.34E-06 1.27E-02 1.73E-Ol 

7.00E+00 9. 64E-03 1.49E-Ol 1. 65E-06 6.06E-03 1.65E-Ol 

8.00E+00 9. 16E-03 1.48E-01 2.92E-07 2.99E-03 1.61E-Ol 

9.00E+00 8. 73E-03 1.48E-Ol 5. 16E-08 1. 55E-03 1. 58E-Ol 

1.00E+Ol 8. 34E-03 1.48E-Ol O.OOE+OO 8.68E-04 1.57E-Ol 

2.00E+Ol 6.06E-03 1.45E-Ol O.OOE+OO 2. 23E-04 1. 52E-Ol 

3.00E+Ol 5. 19E-03 1.43E-Ol O.OOE+OO 2. 19E-04 1.49E-Ol 

4.00E+Ol 4. 78E-03 1.41E-Ol O.OOE+OO 2. 15E-04 1.46E-Ol 

5.00E+Ol 4.52E-03 1.39E-Ol O.OOE+OO 2.11E-04 1.44E-Ol 

6.00E+Ol 4. 33E-03 1. 38E-Ol O.OOE+OO 2.08E-04 1.42E-Ol 

7.00E+Ol 4. 16E-03 1.36E-Ol O.OOE+OO 2.04E-04 1.40E-Ol 

8.00E+Ol 4.02E-03 1.34E-Ol O.OOE+OO 2.00E-04 1. 38E-Ol 

9.00E+Ol 3.90E-03 1.32E-Ol O.OOE+OO 1. 97E-04 1.36E-Ol 

1.00E+02 3. 78E-03 1.30E-Ol O.OOE+OO 1.94E-04 1.34E-Ol 

2.00E+02 3.11E-03 1. 13E-Ol O.OOE+OO 1. 62E-04 1. 17E-Ol 

3.00E+02 2. 83E-03 9. 89E-02 O.OOE+OO 1. 36E-04 1.02E-Ol 

4.00E+02 2. 66E-03 8.64E-02 O.OOE+OO 1. 15E-04 8.92E-02 

5.00E+02 2. 53E-03 7. 56E-02 O.OOE+OO 9.62E-05 7.82E-02 

6.00E+02 2.41E-03 6. 63E-02 O.OOE+OO 8.08E-05 6. 88E-02 

7.00E+02 2. 29E-03 5. 82E-02 O.OOE+OO 6. 78E-05 6.05E-02 

8.00E+02 2. 18E-03 5.11E-02 O.OOE+OO 5.70E-05 5. 34E-02 

9.00E+02 2.06E-03 4.50E-02 O.OOE+OO 4. 78E-05 4.72E-02 

1.00E+03 1.95E-03 3. 97E-02 O.OOE+OO 4.02E-05 4.17E-02 

2.00E+03 1.02E-03 1. 24E-02 O.OOE+OO 7.00E-06 1.34E-02 

3.00E+03 4.70E-04 4. 53E-03 O.OOE+OO 1.22E-06 5.00E-03 

4.00E+03 2.00E-04 1. 95E-03 O.OOE+OO 2. 12E-07 2. 15E-03 

5.00E+03 8.05E-05 9.73E-04 O.OOE+OO 3.70E-08 1.05E-03 

6.00E+03 3. 14E-05 5. 51E-04 O.OOE+OO O.OOE+OO 5. 82E-04 

7.00E+03 1. 19E-05 3.41E-04 O.OOE+OO O.OOE+OO 3. 53E-04 

8.00E+03 4.44E-06 2.23E-04 O.OOE+OO O.OOE+OO 2.27E-04 

9.00E+03 1. 63E-06 1.50E-04 O.OOE+OO O.OOE+OO 1.52E-04 

1.00E+04 5. 94E-07 1.03E-04 O.OOE+OO O.OOE+OO 1.03E-04 

B-377 
CLASS Y AMAD = 1 MICRON HALFLIFE= 1.92E+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1.92E-04 S.8SE-OS 

2.00E-Ol 4.S2E-04 3. 21E-04 

3.00E-Ol 7.90E-04 1.24E-03 

4.00E-Ol 1.2lE-03 3. 32E-03 

5.00E-0l 1.7lE-03 6. 95E-03 

6.00E-Ol 2. 26E-03 1. 24E-02 

7.00E-Ol 2.84E-03 1.96E-02 

8.00E-Ol 3.4SE-03 2. 86E-02 

9.00E-Ol 4.05E-03 3.93E-02 

1.00E+OO 4.64E-03 4. 64E-03 S.15E-02 S.ISE-02 

2.00E+OO 4. 64E-03 9.29E-03 I.S4E-Ol 2.06E-Ol 

3.00E+OO 2.40E-03 I.17E-02 1. 24E-Ol 3.30E-Ol 

4.00E+OO I.2BE-03 1.30E-02 6. 98E-02 4.00E-Ol 

S.OOE+OO B.17E-04 I.38E-02 3.4SE-02 4. 34E-Ol 

6.00E+OO 6.0BE-04 1.44E-02 1.64E-02 4.S0E-Ol 

7.00E+OO 4.97E-04 I.49E-02 7.77E-03 4.S8E-Ol 

B.OOE+OO 4.26E-04 1.53E-02 3.76E-03 4.6lE-OI 

9.00E+OO 3. 74E-04 I.57E-02 1.89E-03 4. 63E-Ol 

I.OOE+Ol 3. 33E-04 I.60E-02 1.0lE-03 4.64E-Ol 

2.00E+Ol 1.2BE-04 I.79E-02 1.60E-04 4.6SE-OI 

3.00E+Ol 6.43E-OS I.B7E-02 1.41E-04 4.6SE-OI 

4.00E+Ol 4.30E-OS 1.92E-02 l~34E-04 4. 64E-Ol 

S.OOE+OI 3.S2E-OS l.9SE-02 l.29E-04 4.64E-Ol 

6.00E+Ol 3. 17E-OS 1.97E-02 1. 27E-04 4. 64E-Ol 

7.00E+Ol 2. 97E-OS 2.00E-02 1.24E-04 4.63E-OI 

B.OOE+Ol 2.B3E-OS 2.02E-02 1. 22E-04 4.63E-Ol 

9.00E+OI 2.70E-OS 2.04E-02 1. 19E-04 4.62E-OI 

I.OOE+02 2.60E-OS 2.06E-02 I. 17E-04 4.62E-Ol 

2.00E+02 1.99E-OS 2.20E-02 9.7BE-OS 4.S6E-OI 

3.00E+02 1.74E-OS 2.3IE-02 B.23E-OS 4.49E-Ol 

4.00E+02 I.S9E-OS 2.39E-02 6.9SE-05 4.40E-Ol 

S.OOE+02 1.48E-OS 2.45E-02 S.B7E-OS 4.3IE-Ol 

6.00E+02 1.3BE-OS 2.S1E-02 4.96E-OS 4.2lE-Ol 

7.00E+02 1. 28E-OS 2.SSE-02 4.20E-OS 4.10E-OI 

8.00E+02 1.19E-05 2.5BE-02 3. S5E-OS 4.00E-Ol 9~OOE+02 1.1OE-OS 2.60E-02 3.0lE-OS 3. 89E-Ol 

1.00E+03 I.02E-OS 2.6IE-02 2.5SE-OS 3.7BE-Ol 

2.00E+03 4.2BE-06 2. 38E-02 S.07E-06 2. 73E-Ol 

3.00E+03 1.66E-06 1.89E-02 1.IIE-06 1.93E-OI 

4.00E+03 6.l7E-07 1.40E-02 2. 76E-07 1.3SE-Ol 

S.OOE+03 2.2SE-07 1.OlE-02 7.7SE-OB 9.40E-02 

6.00E+03 B.13E-08 7.ISE-03 2.40E-08 6.5SE-02 

7.00E+03 2.9IE-08 5.02E-03 O.OOE+OO 4.S7E-02 

8.00E+03 1.04E-08 3. 52E-03 O.OOE+OO 3.18E-02 

B-378 
CLASS Y AMAD= 1 MICRON STABLE COPPER 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 1.20E-02 3.04E-Ol 2. SBE-Ol 6.49E-02 6. 39E-Ol 

2.00E-Ol 3.S7E-02 2. BSE-Ol 2.17E-OI 1.OIE-OI 6. 39E-OI 

3.00E-OI 6. 29E-02 2.70E-0l 1. S2E-OI 1. 23E-0l 6.3BE-Ol 

4.00E-OI 8.7BE-02 2. S7E-OI I.S3E-Ol 1. 38E-Ol 6.37E-Ol 

S.OOE-Ol 1.09E-Ol 2.47E-OI l.29E-Ol 1.49E-Ol 6. 34E-OI 

6.00E-OI 1.27E-Ol 2.3BE-OI I.OBE-OI I. 56E-Ol 6.30E-Ol 

7.00E-Ol 1.43E-Ol 2.3IE-OI 9.12E-02 1.6IE-Ol 6. 26E-Ol 

B.OOE-Ol I.SSE-OI 2. 24E-Ol 7.67E-02 1.64E-OI 6.20E-OI 

9.00E-Ol I. 66E-OI 2.l9E-Ol 6.4SE-02 1. 64E-OI 6.14E-Ol 

l.OOE+OO I. 76E-OI 2. 13E-OI S.42E-02 1.63E-Ol 6.06E-OI 

2.00E+OO 2.l9E-Ol I.80E-Ol 9.S9E-03 I.12E-Ol S.2lE-OI 

3.00E+OO 2.2BE-OI I.6SE-OI 1.70E-03 S.9lE-02 4.S4E-OI 

4.00E+OO 2.30E-OI I.S7E-Ol 3.00E-04 2.B5E-02 4. 15E-OI 

S.OOE+OO 2.2BE-Ol 1. S3E-Ol S.30E-OS I.34E-02 3. 94E-Ol 

6.00E+OO 2.2SE-Ol l.SIE-Ol 9. 37E-06 6.3IE-03 3.82E-OI 

7.00E+OO 2. 22E-OI 1.49E-OI 1. 66E-06 3.03E-03 3. 74E-OI 

B.OOE+OO 2.IBE-Ol I.49E-Ol 2. 93E-07 I.SOE-03 3.69E-Ol 

9.00E+OO 2.lSE-Ol 1.4BE-OI S.17E-OB 7.8SE-04 3. 64E-OI 

1.OOE+OI 2.IIE-OI 1.48E-OI O.OOE+OO 4. 43E-04 3.60E-Ol 

2.00E+Ol 1.79E-Ol I.46E-Ol O.OOE+OO I.2lE-04 3.2SE-Ol 

3.00E+Ol I.SIE-OI 1.4SE-Ol O.OOE+OO 1.I9E-04 2.96E-OI 

4.00E+OI 1. 28E-Ol 1.43E-Ol O.OOE+OO 1.17E-04 2. 71E-Ol 

S.OOE+Ol I.OBE-OI 1.42E-0l O.OOE+OO 1.16E-04 2.S0E-Ol 

6.00E+Ol 9.l7E-02 1.4lE-Ol O.OOE+OO 1.I4E-04 2. 32E-Ol 

7.00E+OI 7. 79E-02 1. 39E-OI O.OOE+OO 1. 13E-04 2.17E-OI 

8.00E+OI 6. 62E-02 I.3BE-OI O.OOE+OO 1.llE-04 2.04E-OI 

9.00E+Ol S.64E-02 I.36E-Ol O.OOE+OO I.09E-04 1. 93E-Ol 

I.OOE+02 4.B2E-02 1.3SE-Ol O.OOE+OO I.OBE-04 1.B3E-OI 

2.00E+02 I.20E-02 I.22E-Ol O.OOE+OO 9.40E-OS 1. 34E-OI 

3.00E+02 S.2BE-03 I.lOE-OI O.OOE+OO B.lBE-OS I.I6E-OI 

4.00E+02 3. BOE-03 9. 98E-02 O.OOE+OO 7.12E-OS I.04E-OI 

S.OOE+02 3. 27E-03 9.06E-02 O.OOE+OO 6.20E-OS 9.39E-02 

6.00E+02 2. 94E-03 8. 23E-02 O.OOE+OO S.40E-OS B. S3E-02 

7.00E+02 2. 67E-03 7.49E-02 O.OOE+OO 4.70E-OS 7. 76E-02 

8.00E+02 2. 43E-03 6.B3E-02 O.OOE+OO 4.09E-OS 7.0BE-02 

9.00E+02 2. 22E-03 6.23E-02 O.OOE+OO 3.S6E-OS 6. 46E-02 

I.OOE+03 2.03E-03 S.70E-02 O.OOE+OO 3.lOE-OS S.9IE-02 

2.00E+03 B.S7E-04 2.SSE-02 O.OOE+OO 7.7SE-06 2. 63E-02 

3.00E+03 3.B9E-04 1. 34E-02 O.OOE+OO. 1. 94E-06 1.38E-02 

4.00E+03 1. BSE-04 8.2SE-03 O.OOE+OO 4.B4E-07 8. 43E-03 

S.OOE+03 9.00E-OS S.92E-03 O.OOE+OO I.2lE-07 6.0IE-03 

6.00E+03 4.44E-OS 4.8IE-03 O.OOE+OO 3.03E-OB 4.8SE-03 

7.00E+03 2.2IE-OS 4.27E-03 O.OOE+OO O.OOE+OO 4. 29E-03 

8.00E+03 I.lOE-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.0IE-03 

9.00E+03 S.49E-06 3.S7E-03 O.OOE+OO O.OOE+OO 3. 87E-03 

1.OOE+04 2. 74E-06 3.80E-03 O.OOE+OO O.OOE+OO 3.8IE-03 

B-379 
CLASS Y AMAD = 1 MICRON STABLE COPPER 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACClJr.fULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 9. 97E-06 9 •. 50E-06 

2.00E-01 5.01E-05 1. 76E-04 

3.00E-01 1.36£-04 8.23E-04 

4.00E-01 2. 67E-04 2. 25E-03 

5.00E-01 4. 38E-04 4. 65E-03 

6.00E-01 6.43E-04 8.07E-03 

7.00E-01 8. 77E-04 1.25E-02 

8.00E-01 1. 14E-03 1.79E-02 

9.00E-01 1. 42E-03 2.41E-02 

1.00E+00 1.71E-03 1.71E-03 3.lOE-02 3.10E-02 

2.00E+00 3.50E-03 5. 22E-03 8.22E-02 1.13E-01 

3.00E+00 3. 89E-03 9.11E-03 6.31E-02 1. 76E-01 

4.00E+00 3. 97E-03 1.31E-02 3.47E-02 2.11E-Ol 

5.00E+00 3. 97E-03 1.70E-02 1.70E-02 2. 28E-01 

6.00E+00 3. 93E-03 2.10E-02 8.05E-03 2.36E-Ol 

7.00E+00 3. 87E-03 2. 48E-02 3. 79E-03 2.40E-01 

8.00E+00 3. 82E-03 2.87E-02 1.82E-03 2.42E-01 

9.00E+00 3.75E-03 3.24E-02 8. 97E-04 2. 43E-Ol 

1.00E+Ol 3. 69E-03 3.61E-02 4.65E-04 2.43E-Ol 

2.00E+Ol 3. 12E-03 6. 98E-02 6. 78E-05 2. 44E-Ol 

3.00E+Ol 2. 64E-03 9.83E-02 6. 65E-05 2.45E-01 

4.00E+01 2.23E-03 1.22E-Ol 6. 56E-05 2.45E-01 

5.00E+01 1.89E-03 1.43E-Ol 6. 47E-05 2.46E-01 

6.00E+Ol 1.60E-03 1.60E-01 6. 38E-05 2.47E-01 

7.00E+01 1 .. 36E-03 1. 75E-01 6.29E-05 2.47E-0l 

8.00E+01 1. 16E-03 1.87E-Ol 6.20E-05 2.48E-Ol 

9.00E+Ol 9. 85E-04 1. 98E-Ol 6. 12E-05 2.49E-Ol 

1.00E+02 8.41E-04 2.07E-Ol 6.03E-05 2.49E-01 

2.00E+02 2.09E-04 2.50E-Ol 5. 25E-05 2.55E-Ol 

3.00E+02 9. 17E-05 2. 64E-Ol 4. 57E-05 2.60E-01 

4.00E+02 6. 59E-05 2.71E-01 3. 98E-05 2.64E-01 

5.00E+02 5. 67E-05 2. 78E-Ol 3. 47E-05 2. 68E-Ol 

7.00E+02 4.63E-05 2.88E-01 2. 63E-05 2. 74E-Ol 

8.00E+02 4. 22E-05 2.92E-01 2. 29E-05 2. 76E-01 

9.00E+02 3. 85E-05 2. 96E-Ol 1.99E-05 2. 78E-01 

1.00E+03 3. 51E-05 3.00E-Ol 1.73E-05 2.80E-01 

2.00E+03 1.49E-05 3.23E-01 4. 33E-06 2.90E-01 

3.00E+03 6. 75E-06 3. 33E-01 1.08E-06 2. 92E-01 

4.00E+03 3.21E-06 3.38E-01 2.71E-07 2. 93E-01 

5.00E+03 1. 56E-06 3.40E-01 6.77E-08 2.93E-Ol 

7.00E+03 3. 82E-07 3. 42E-01 O.OOE+OO 2.93E-Ol 

8.00E+03 1.90E-07 3.42E-01 O.OOE+OO 2. 93E-01 

9.00E+03 9.51E-08 3.43E-Ol O.OOE+OO 2. 93E-01 

1.00E+04 4. 75E-08 3. 43E-01 O.OOE+OO 2. 93E-01 

B-380 
CLASS Y AMAD= 1 MICRON STABLE ZINC 66 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-OI 1.20E-02 3.04E-OI 2. S8E-OI 6.49E-02 6.39E-OI 

2.00E-Ol 3.S7E-02 2.8SE-OI 2.17E-OI 1.OIE-Ol 6. 39E-OI 

3.00E-OI 6.29E-02 2.70E-Ol 1.82E-Ol I.23E-OI 6. 38E-OI 

4.00E-Ol 8. 79E-02 2.S7E-Ol 1.S3E-OI 1. 38E-Ol 6.37E-OI 

S.OOE-OI 1.09E-Ol 2.47E-Ol I. 29E-OI I.49E-OI 6. 34E-OI 

6.00E-OI 1.28E-OI 2. 38E-OI I.08E-OI 1.S6E-OI 6.3lE-OI 

7.00E-Ol 1.43E-Ol 2.3IE-Ol 9.12E-02 I.6IE-Ol 6. 26E-OI 

8.00E-Ol I.S6E-Ol 2. 24E-Ol 7.67E-02 1. 64E-Ol 6.2IE-OI 

9.00E-OI 1. 67E-Ol 2.l9E-Ol 6.4SE-02 1.64E-Ol 6.l4E-Ol 

1.00E+OO I. 76E-Ol 2.BE-Ol S.42E-02 I. 63E-Ol 6.07E-OI 

2.00E+OO 2.2lE-Ol I.80E-OI 9. S9E-03 1.12E-Ol S.23E-Ol 

3.00E+OO 2. 32E-Ol 1.6SE-Ol I.70E-03 S.9lE-02 4.S8E-Ol 

4.00E+OO 2. 36E-Ol 1.S7E-Ol 3.00E-04 2.8SE-02 4.2lE-OI 

S.OOE+OO 2. 36E-Ol 1.S3E-Ol S.30E-OS 1. 34E-02 4.02E-Ol 

6.00E+OO 2.3SE-Ol 1. SlE-Ol 9. 37E-06 6.3lE-03 3.92E-Ol 

7.00E+OO 2.34E-OI 1. 49E-OI 1. 66E-06 3.03E-03 3. 86E-OI 

8.00E+OO 2. 32E-Ol I.49E-Ol 2.93E-07 1. SOE-03 3. 82E-Ol 

9.00E+OO 2.30E-Ol 1. 48E-OI S.17E-08 7.85E-04 3. 79E"";Ol 

l.OOE+Ol 2.29E-Ol 1. 48E-0l O.OOE+OO 4. 43E-04 3.77E-OI 

2.00E+Ol 2.l4E-Ol 1. 46E-Ol O.OOE+OO 1.2lE-04 3.60E-Ol 

3.00E+Ol 2.02E-Ol 1.4SE-Ol O.OOE+OO I.19E-04 3.47E-Ol 

4.00E+Ol 1.93E-Ol 1. 43E-Ol O.OOE+OO 1.17E-04 3.37E-OI 

S.OOE+Ol 1.87E-Ol 1.42E-Ol O.OOE+OO 1.16E-04 3.29E-Ol 

6.00E+Ol 1.8IE-Ol 1.4lE-Ol O.OOE+OO 1.14E-04 3. 22E-Ol 

7.00E+OI l.76E-Ol 1. 39E-Ol O.OOE+OO I.I3E-04 3.l6E-OI 

8.00E+Ol 1. 73E-Ol 1. 38E-Ol O.OOE+OO 1.llE-04 3.lOE-Ol 

9.00E+Ol 1.69E-0l I.36E-Ol O.OOE+OO 1.09E-04 3.06E-Ol 

l.OOE+02 1.66E-Ol 1.3SE-Ol O.OOE+OO 1.08E-04 3.0lE-Ol 

2.00E+02 1.43E-OI I.22E-Ol O.OOE+OO 9.40E-05 2.6SE-Ol 

3.00E+02 1. 25E-0l 1.IOE-OI O.OOE+OO 8.18E-OS 2. 36E-Ol 

4.00E+02 1. IOE-OI 9. 98E-02 O.OOE+OO 7.l2E-05 2.l0E-OI 

5.00E+02 9. 62E-02 9.06E-02 O.OOE+OO 6.20E-05 I.87E-Ol 

6.00E+02 8. 44E-02 8. 23E-02 O.OOE+OO S.40E-OS 1.67E-Ol 

7.00E+02 7.42E-02 7. 49E-02 O.OOE+OO 4.70E-OS 1.49E-Ol 

8.00E+02 6. 54E-02 6.83E-02 O.OOE+OO 4.09E-05 1.34E-Ol 

9.00E+02 S.77E-02 6. 23E-02 O.OOE+OO 3. 56E-OS 1.20E-Ol 

I.OOE+03 5.l0E-02 5.70E-02 O.OOE+OO 3.lOE-05 I.08E-OI 

2.00E+03 1.62E-02 2.5SE-02 O.OOE+OO 7.7SE-06 4.l7E-02 

3.00E+03 6.06E-03 1.34E-02 O.OOE+OO I.94E-06 1. 94E-02 

4.00E+03 2.S7E-03 8.2SE-03 O.OOE+OO 4. 84E-07 I.08E-02 

S.OOE+03 1.18E-03 S.92E-03 O.OOE+OO 1.2IE-07 7.09E-03 

7.00E+03 2.7SE-04 4. 27E-03 O.OOE+OO O.OOE+OO 4.S4E-03 

8.00E+03 1. 36E-04 4.00E-03 O.OOE+OO O.OOE+OO 4.l4E-03 

9.00E+03 6.77E-OS 3. 87E-03 O.OOE+OO O.OOE+OO 3. 94E-03 

1.OOE+04 3. 38E-OS 3.80E-03 O.OOE+OO O.OOE+OO 3. 84E-03 

2.00E+04 3.29E-08 .3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-38l 
CLASS Y AHAD = 1 MICRON STABLE ZINC 66 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.00E-01 1.39E-06 1.37E-OS 

2.00E-Ol 6. 96E-06 1. 97E-04 

3.00E-01 1.88E-OS 8.80E-04 

4.00E-Ol 3.70E-05 2. 36E-03 

5.00E-Ol 6.08E-05 4.83E-03 

6.00E-Ol 8. 93E-05 8. 34E-03 

7.00E-Ol 1.22E-04 1.29E-02 

B.OOE-01 1. 58E-04 1. 84E-02 

9.00E-Ol 1.96E-04 2.47E-02 

l.OOE+OO 2.37E-04 2. 37E-04 3. 17E-02 3.l7E-02 

2.00E+OO 4.82E-04 7.l9E-04 8.36E-02 l.l5E-0l 

3.00E+OO 5. 29E-04 l.25E-03 6. 46E-02 I.80E-Ol 

4.00E+OO 5. 34E-04 l.78E-03 3.63E-02 2.16E-01 

S.OOE+OO 5. 27E-04 2.3lE-03 1.86E-02 2. 35E-01 

6.00E+OO 5. 15E-04 2. 82E-03 9.60E-03 2.45E-OI 

7.00E+OO 5.03E-04 3. 33E-03 5.30E-03 2.50E-Ol 

8.00E+OO 4.89E-04 3.82E-03 3. 28E-03 2. 53E-Ol 

9.00E+OO 4. 76E-04 4. 29E-03 2. 32E-03 2. 55E-01 

I.OOE+OI 4. 62E-04 4.75E-03 1.8SE-03 2.57E-Ol 

2.00E+Ol 3.5IE-04 8.73E-03 1.l2E-03 2.70E-OI 

3.00E+Ol 2. 72E-04 I.I8E-02 8.8IE-04 2.80E-Ol 

4.00E+OI 2.15E-04 I.42E-02 7.1lE-04 2. 88E-Ol 

5.00E+Ol 1.75E-04 1. 61E-02 S.90E-04 2. 94E-01 

6.00E+OI 1. 46E-04 . I.77E-02 5.03E-04 3.00E-Ol 

7.00E+Ol 1.26E-04 I.90E-02 4.40E-04 3.04E-Ol 

8.00E+Ol 1. llE-04 2.02E-02 3.9SE-04 3.09E-Ol 

9.00E+Ol I.OOE-04 2.12E-02 3. 62E-04 3.12E-Ol 

I.OOE+02 9. 23E-05 2.22E-02 3. 37E-04 3.16E-Ol 

2.00E+02 6. 67E-05 2.97E-02 2. 53E-04 3.44E-Ol 

3.00E+02 5.80E-OS 3. 59E-02 2.20E-04 3. 68E-Ol 

4.00E+02 5.09E-05 4. 14E-02 1.92E-04 3.88E-Ol 

5.00E+02 4.47E-OS 4. 62E-02 1. 69E-04 4.06E-Ol 

6.00E+02 3. 94E-05 5.03E-02 1.48E-04 4.22E-Ol 

7.00E+02 3.47E-05 5.40E-02 1.30E-04 4.36E-Ol 

8.00E+02 3.06E-05 5.73E-02 I.I5E-04 4.48E-Ol 

9.00E+02 2.7IE-OS 6.02E-02 1.01E-04 4.59E-OI .. 1.00E+03 2.40E-05 6. 27E-02 8.93E-05 4.68E-Ol 

2.00E+03 7.84E-06 7.70E-02 2. 78E-05 5.20E-OI 

3.00E+03 3.00E-06 8. 19E-02 1.0lE-05 S.38E-OI 

4.00E+03 1.29E-06 8.40E-02 4. 14E-06 5.44E-Ol 

5.00E+03 5.96E-07 8.48E-02 I.86E-06 S.47E-01 

6.00E+03 2. 86E-07 8.53E-02 8.76E-07 5.48E-Ol 

7.00E+03 1.40E-07 8.S5E-02 4.26E-07 5.49E-OI 

8.00E+03 6. 96E-08 8. 56E-02 2.lOE-07 5.49E-Ol 

9.00E+03 3.46E-'08 8.56E-02 1.04E-07 5.50E-01 

1.OOE+04 1.73E-08 8. 56E-02 5. 19E-08 5.S0E-Ol 

B-382 
CLASS Y AHA.D = 1 MICRON HALFLIFE- 2.44E+02 DAYS ZINC 65 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 1.20E-02 3.04E-Ol 2.S8E-Ol 6. 49E-02 6. 39E-Ol 

2.00E-Ol 3.S7E-02 2. 85E-Ol 2.l7E-Ol 1.OlE-Ol 6.39E-Ol 

3.00E-Ol 6.29E-02 2.70E-0l 1.82E-Ol 1.23E-Ol 6. 38E-Ol 

4.00E-Ol B.78E-02 2.S7E-Ol 1. 53E-Ol 1.3BE-Ol 6. 36E-Ol 

5.00E-Ol 1.09E-Ol 2.47E-0l 1. 29E-Ol 1. 48E-Ol 6. 33E-Ol 

6.00E-Ol 1.27E-Ol 2. 38E-Ol 1.OBE-Ol 1. S6E-Ol 6.30E-Ol 

7.00E-Ol 1.43E-Ol 2.30E-Ol 9.llE-02 1.6lE-Ol 6.25E-Ol 

B.OOE-Ol 1.56E-Ol 2. 24E-Ol 7.6SE-02 1. 63E-Ol 6.l9E-Ol 

9.00E-Ol 1.67E-0l 2.l8E-Ol 6. 43E-02 1.64E-Ol 6. 13E-Ol 

1.OOE+OO 1. 76E-Ol 2.l3E-Ol 5.4lE-02 1. 63E-Ol 6.05E-Ol 

2.00E+OO 2.20E-Ol 1.79E-Ol 9.S4E-03 1.llE-Ol 5.20E-Ol 

3.00E+OO 2.30E-Ol 1. 63E-Ol 1. 68E-03 5. 86E-02 4. 54E-Ol 

4.00E+OO 2. 33E-Ol 1.55E-0l 2. 96E-04 2.B2E-02 4.l6E-0l 

5.00E+OO 2. 32E-Ol 1.50E-OI S.22E-OS 1. 32E-02 3. 96E-Ol 

6.00E+OO 2. 31E-0l 1.4BE-OI 9.2lE-06 6.20E-03 3. BSE-Ol 

7.00E+OO 2. 29E-Ol 1. 46E-Ol 1. 62E-06 2.97E-03 3.7BE-Ol 

B.OOE+OO 2. 27E-Ol 1. 45E-Ol 2. 86E-07 1. 47E-03 3. 74E-Ol 

9.00E+OO 2.24E-Ol 1.4SE-Ol S.04E-08 7. 65E-04 3.70E-Ol 

1.OOE+Ol 2. 22E-Ol 1. 44E-Ol O.OOE+OO 4.3lE-04 3. 66E-Ol 

2.00E+Ol 2.02E-Ol I.3BE-Ol O.OOE+OO 1.14E-04 3.40E-Ol 

3.00E+OI 1.B6E-Ol 1.33E-Ol O.OOE+OO I.09E-04 3.l9E-OI 

4.00E+Ol 1.73E-Ol 1. 28E-Ol O.OOE+OO 1.OSE-04 3.0lE-Ol 

S.OOE+Ol I.62E-Ol 1.23E-Ol O.OOE+OO 1.OOE-04 2. BSE-Ol 

6.00E+Ol 1.S3E-Ol 1.18E-Ol O.OOE+OO 9. 62E-05 2.7lE-Ol 

7.00E+Ol 1.4SE-Ol 1.14E-0l O.OOE+OO 9.22E-OS 2. 59E-Ol 

B.OOE+Ol 1.37E-OI 1. lOE-Ol O.OOE+OO 8.B4E-OS 2. 47E-Ol 

9.00E+Ol I.3IE-Ol 1.06E-OI O.OOE+OO B.48E-OS 2. 37E-Ol 

1.OOE+02 I.25E-Ol 1.OlE-OI O.OOE+OO B.13E-OS Z.27E-Ol 

2.00E+02 8.l2E-02 6.90E-02 O.OOE+OO S.32E-OS 1. SOE-Ol 

3.00E+02 5.34E-02 4.70E-02 O.OOE+OO 3.49E-OS 1.OOE-Ol 

4.00E+02 3.S2E-02 3.20E-02 O.OOE+OO 2. 29E-OS 6.72E-02 

5.00E+02 2. 32E-02 2.I9E-02 O.OOE+OO 1.SOE-OS 4.SlE-02 

6.00E+02 1. 53E-02 1. SOE-02 O.OOE+OO 9.BIE-06 3.03E-02 

7.00E+02 1.02E-02 I.02E-02 O.OOE+OO 6. 43E-06 2.04E-02 

B.OOE+02 6. 73E-03 7.03E-03 O.OOE+OO 4.2lE-06 1.3BE-02 

9.00E+02 4.47E-03 4. 83E-03 O.OOE+OO 2. 76E-06 9.30E-03 

1.OOE+03 2. 97E-03 3.32E-03 O.OOE+OO 1. BlE-06 6.30E-03 ... J 2.00E+03 S.SIE-05 8.66E-OS O.OOE+OO 2.64E-OB 1. 42E-04 

3.00E+03 I.20E-06 2.6SE-06 O.OOE+OO O.OOE+OO 3.B5E-06 

4.00E+03 2. 97E-OB 9.S4E-08 O.OOE+OO O.OOE+OO 1.2SE-07 

B-3B3 
CLASS Y AHA» = 1 MICRON HALFLIlE= 2.44E+02 DAYS ZINC 65 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 1. 39E-06 I.37E-OS 

2.00E-01 6. 96E-06 1. 96E-04 

3.00E-Ol 1.B8E-OS B.79E-04 

4.00E-OI 3.70E-OS 2. 36E-03 

S.OOE-OI 6.07E-OS 4. 82E-03 

6.00E-OI 8.9IE-OS B.32E-03 

7.00E-OI 1. 22E-04 1.29E-02 

8.00E-01 1. S7E-04 I.B3E-02 

9.00E-OI 1. 96E-04 2.46E-02 

1.00E+OO 2. 36E-04 2. 36E-04 3.16E-02 3.16E-02 

2.00E+OO 4. 79E-04 7.ISE-04 B.32E-02 I.ISE-OI 

3.00E+OO 5.2SE-04 1. 24E-03 6.4IE-02 1. 78E-01 

4.00E+OO S.2BE-04 1. 76E-03 3.S9E-02 2.14E-OI 

5.00E+OO 5.19E-04 2.2BE-03 1. 84E-02 2. 32E-OI 

6.00E+OO S.07E-04 2.7BE-03 9.43E-03 2.40E-OI 

7.00E+OO 4. 93E-04 3. 26E-03 S.20E-03 2.45E-01 

8.00E+OO 4.7BE-04 3. 73E-03 3.2IE-03 2.47E-OI 

9.00E+OO 4. 64E-04 4.18E-03 2. 27E-03 2.49E-OI 

I.OOE+OI 4. SOE-04 4. 62E-03 1.80E-03 2.50E-01 

2.00E+0l 3. 32E-04 8. 25E-03 I.06E-03 2.S5E-Ol 

3.00E+01 2. 49E-04 I.OBE-02 8.09E-04 2. 57E-OI 

4.00E+OI 1.92E-04 1. 27E-02 6.3SE-04 2. 57E-OI 

S.OOE+OI 1. S2E-04 1.40E-02 5.12E-04 2.55E-01 

6.00E+OI 1. 23E-04 1. 49E-02 4. 24E-04 2.S3E-OI 

7.00E+OI I.03E-04 1. S6E-02 3.6IE-04 2.S0E-OI 

8.00E+OI 8. 84E-05 I.6IE-02 3. ISE-04 2.46E-OI 

9.00E+OI 7.76E-05 1.6SE-02 2. BOE-04 2.42E-OI 

I.OOE+02 6.9SE-OS I.67E-02 2.S4E-04 2. 38E-OI 

2.00E+02 3. 78E-OS 1. 68E-02 I.43E-04 1.9SE-OI 

3.00E+02 2. 47E-OS I.S3E-02 9. 37E-OS 1. S7E-OI 

4.00E+02 I.63E-05 1. 33E-02 6.18E-05 1.25E-OI 

S.OOE+02 I.OBE-05 1.IIE-02 4.0BE-OS 9.8IE-02 

6.00E+02 7.ISE-06 9.15E-03 2. 69E-OS 7.67E-02 

7.00E+02 4.7SE-06 7.39E-03 I.7BE-OS S.96E-02 

8.00E+02 3.ISE-06 S.90E-03 1.IBE-OS 4.6IE-02 

9.00E+02 2.10E-06 4. 66E-03 7. 84E-06 3. 56E-02 

I.OOE+03 1.40E-06 3. 66E-03 S.2IE-06 2. 73E-02 

2.00E+03 2. 67E-OB 2. 62E-04 9.47E-OB I.77E-03 

B-3B4 
CLASS Y AHA» = 1 MICRON BALFLIFE= 6.48E+Ol DAYS STRONTIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. SOE-03 3.04E-Ol 2.SBE-Ol 7.29E-02 6.3BE-Ol 

2.00E-Ol 3.6BE-03 2.B4E-Ol 2.l7E-Ol 1.32E-Ol 6.37E-Ol 

3.00E-Ol 4.0lE-03 2. 69E-Ol 1. B2E-Ol 1. BOE-Ol 6.3SE-Ol 

4.00E-Ol 4. 34E-03 2.S6E-Ol 1.S3E-Ol 2.l9E-Ol 6.32E-Ol 

S.OOE-Ol 4.6SE-03 2.46E-Ol 1.2BE-Ol 2. 49E-Ol 6.2BE-Ol 

6.00E-Ol 4.92E-03 2. 37E-Ol 1.OBE-Ol 2. 72E-Ol 6.22E-Ol 

7.00E-Ol S.14E-03 2.29E-Ol 9.06E-02 2. B9E-Ol 6.l4E-Ol 

B.OOE-Ol S.3lE-03 2.22E-Ol 7.6lE-02 3.00E-Ol 6.04E-Ol 

9.00E-Ol S.4SE-03 2.l6E-Ol 6.39E-02 3.07E-Ol S.93E-Ol 

1.OOE+OO S.S6E-03 2. llE-Ol S.37E-02 3.09E-Ol S.BOE-Ol 

2.00E+OO S.66E-03 1.77E-Ol 9. 39E-03 2.2SE-Ol 4.l7E-Ol 

3.00E+OO S.20E-03 1.S9E-Ol 1. 64E-03 1.20E-Ol 2.B6E-Ol 

4.00E+OO 4.70E-03 1. SOE-Ol 2. B7E-04 S.7SE-02 2.13E-Ol 

S.OOE+OO 4. 24E-03 1.4SE-Ol S.02E-OS 2.6BE-02 1. 76E-Ol 

6.00E+OO 3. BSE-03 1.4lE-Ol B.7BE-06 1.2SE-02 l.SBE-Ol 

7.00E+OO 3.SlE-03 1. 39E-Ol 1.S4E-06 S.9lE-03 1.4BE-Ol 

B.OOE+OO 3.22E-03 1.37E-Ol 2.69E-07 2.B9E-03 1.43E-Ol 

9.00E+OO 2. 97E-03 1.3SE-Ol 4.70E-OB 1.4BE-03 1. 39E-Ol 

1.OOE+Ol 2.76E-03 1.33E-Ol O.OOE+OO B.lBE-04 1.37E-Ol 

2.00E+Ol 1. 73E-03 1.lBE-Ol O.OOE+OO 1.B9E-04 1.20E-Ol 

3.00E+Ol 1.42E-03 1.OSE-Ol O.OOE+OO 1.67E-04 1.07E-Ol 

4.00E+Ol 1.2SE-03 9.3SE-02 O.OOE+OO 1.4BE-04 9.49E-02 

S.OOE+Ol 1.12E-03 B.32E-02 O.OOE+OO 1.3lE-04 B.44E-02 

6.00E+Ol 1.OlE-03 7.40E-02 O.OOE+OO 1.16E-04 7.SlE-02 

7.00E+Ol 9.06E-04 6. SBE-02 O.OOE+OO 1.03E-04 6.6BE-02 

B.OOE+Ol B.16E-04 S.BSE-02 O.OOE+OO 9.l3E-OS S.94E-02 

9.00E+Ol 7. 36E-04 S.2lE-02 O.OOE+OO B.09E-OS S.29E-02 

1.OOE+02 6. 64E-04 4. 63E-02 O.OOE+OO 7.l7E-OS 4.70E-02 

2.00E+02 2.42E-04 1. 44E-02 O.OOE+OO 2.l4E-OS 1. 46E-02 

3.00E+02 B.9SE-OS 4. 46E-03 O.OOE+OO 6.4lE-06 4.S6E-03 

4.00E+02 3.3lE-OS 1.39E-03 O.OOE+OO 1.92E-06 1. 42E-03 

S.OOE+02 1.2lE-OS 4. 32E-04 O.OOE+OO S.72E-07 4.4SE-04 

6.00E+02 4. 43E-06 1.3SE-04 O.OOE+OO 1.71E-07 1. 39E-04 

7.00E+02 1.6lE-06 4.2lE-OS O.OOE+OO S.llE-OB 4.3BE-OS 

B.OOE+02 S. BOE-07 1. 32E-OS O.OOE+OO 1. S3E-OB 1.3BE-OS 

9.00E+02 2.0BE-07 4.l3E-06 O.OOE+OO O.OOE+OO 4. 34E-06 

1.OOE+03 7. 42E-OB 1.30E-06 O.OOE+OO O.OOE+OO 1. 37E-06 

B-3BS 
CLASS Y AMAD - 1 KICRON BALFLlFE= 6.48E+OI DAYS STRONTIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 4.lBE-04 B.42E-05 

2.00E-Dl 5.3BE-04 3.D4E-04 

3.00E-Ol 6.34E-04 1. 16E-03 

4.00E-Dl 7. 35E-04 3.1BE-03 

5. DOE-Dl B.39E-04 6. 75E-03 

6.00E-Dl 9.42K-04 1.2lE-02 

7.00E-Ol 1.04E-03 1.94E-02 

B.OOE-Ol 1. 14E-03 2. 84E-02 

9.00E-Ol 1.23E-03 3. 92E-02 

1.00E+OO 1. 32E-03 l.32E-03 5. 14E-02 5. 14E-02 

2.00E+OO 7. 73E-04 2.08E-03 1.56E-Ol 2.07E-Ol 

3.00E+OO 6.03E-04 2. 66E-03 1.26E-Ol 3.30E-Ol 

4.00E+OO 4.87E-04 3.l2E-03 6.99E-02 3. 97E-Ol 

5.00E+OO 4.00E-04 3.49E-03 3.42E-02 4. 27E-Ol 

6.00E+OO 3. 32E-04 3. 78E-03 1.61E-02 4. 38E-Ol 

7.00E+OO 2.78E-04 4.02E-03 7.5lE-03 4.41E-Ol 

B.OOE+OO 2. 34E-04 4.2lE-03 3.57E-03 4.40E-Ol 

9.00E+OO 1. 98E-04 4. 36E-03 1. 75E-03 4.37E-Ol 

1.OOE+Ol 1.6BE-04 4. 49E-03 9.05E-04 4. 33E-Ol 

2.00E+Ol 4.09E-05 4. 79E-03 l.16E-04 3. 91E-Ol 

3.00E+Ol 1. 69E-05 4. 54E-03 9.B5E-05 3. 52E-Ol 

4.00E+Ol 1.14E-05 4.2lE-03 B.67E-05 3.l8E-0l 

S.OOE+Ol 9. 54E-06 3.BBE-03 7.67E-OS 2.86E-Ol 

6.00E+OI B.39E-06 3.57E-03 6. BOE-05 2.5BE-OI 

7.00E+Ol 7.4BE-06 3.2BE-03 6.03E-OS 2.32E-Ol 

B.OOE+Ol 6. 68E-06 3.02E-03 S.34E-05 2.09E-Ol 

9.00E+Ol S.97E-06 2.77E-03 4.73E-05 I.B9E-Ol 

1.OOE+02 5.3SE-06 2.S4E-03 4.20E-OS 1.70E-Ol 

2.00E+02 I. BOE-06 1.OSE-03 1. 26E-OS S.97E-02 

3.00E+02 6.llE-07 4. 23E-04 3.77E-06 2.09E-02 

4.00E+02 2.0BE-07 1 .. 66E-04 l.l3E-06 7. 29E-03 

5.00E+02 7.03E-OB 6. 42E-OS 3.40E-07 2.S4E-03 

6.00E+02 2. 37E-OB 2. 44E-05 1.02E-07 8.83E-04 

B-386 
CLASS Y AMAD = 1 KICR.ON STABLE STRONTIUM 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3.50E-03 3.04E-01 2.58E-0l 7.30E-02 6. 39E-01 

2.00E-Ol 3. 69E-03 2.S5E-01 2. 17E-Ol 1. 33E-01 6.3SE-01 

3.00E-01 4.02E-03 2.70E-Ol I.S2E-Ol l .. SlE-Ol 6.37E-Ol 

4.00E-Ol 4. 36E-03 2. 57E-Ol 1.53E-01 2.20E-Ol 6.35E-Ol 

5.00E-Ol 4.6SE-03 2.47E-Ol 1.29E-01 2.51E-0l 6.31E-Ol 

6.00E-Ol 4. 95E-03 2.3SE-01 1.0SE-01 2. 74E-Ol 6. 26E-Ol 

7.00E-Ol S.17E-03 2.31E-01 9. 12E-02 2.91E-0l 6. 19E-Ol 

8.00E-Ol 5. 36E-03 2. 24E-Ol 7. 67E-02 3.03E-Ol 6.09E-Ol 

9.00E-Ol 5.S1E-03 2. 19E-Ol 6.45E-02 3.l0E-0l 5.9SE-01 

1.00E+00 S.62E-03 2.l3E-Ol S.42E-02 3. 13E-Ol 5.S6E-01 

2.00E+00 S.7SE-03 I.S0E-Ol 9. S9E-03 2.30E-01 4. 26E-01 

3.00E+00 5.37E-03 1. 65E-Ol 1.70E-03 1. 24E-01 2.9SE-Ol 

4.00E+00 4.90E-03 1.S7E-01 3.00E-04 6.00E-02 2.22E-01 

5.00E+00 4. 47E-03 1.S3E-01 S.30E-05 2.S3E-02 1.SSE-01 

6.00E+00 4.lOE-03 1. SIE-Ol 9. 37E-06 1.33E-02 1.6SE-Ol 

7.00E+OO 3.7SE-03 1. 49E-01 1. 66E-06 6.37E-03 1.60E-01 

S.OOE+OO 3.50E-03 l.49E"';01 2. 93E-07 3.l4E-03 I.SSE-01 

9.00E+00 3. 27E-03 1. 48E-01 S.17E-OS 1. 63E-03 1.S3E-01 

1.00E+Ol 3.07E-03 1.4SE-Ol O.OOE+OO 9.l1E-04 I.S2E-Ol 

2.00E+OI 2. 15E-03 1. 46E-Ol O.OOE+OO 2. 34E-04 1.49E-Ol 

3.00E+Ol 1.96E-03 1.4SE-0l O.OOE+OO 2.30E-04 l.47E-01 

4.00E+01 1.92E-03 1.43E-01 O.OOE+OO 2. 27E-04 1.46E-01 

5.00E+Ol 1.91E-03 1. 42E-Ol O.OOE+OO 2. 24E-04 1.44E-01 

6.00E+01 1. 91E-03 1. 41E-Ol O.OOE+OO 2. 21E-04 1. 43E-Ol 

7.00E+Ol 1.91E-03 1.39E-0l O.OOE+OO 2.1SE-04 1.41E-01 

S.00E+01 1. 92E-03 1.3SE-01 O.OOE+OO 2.1SE-04 1.40E-Ol 

9.00E+01 1.93E-03 1.36E-Ol O.OOE+OO 2. 12E-04 1.3SE-Ol 

1.00E+02 1. 93E-03 1.3SE-Ol O.OOE+OO 2.09E-04 1. 37E-Ol 

2.00E+02 2.0SE-03 1.22E-Ol O.OOE+OO 1.S2E-04 1. 24E-Ol 

3.00E+02 2. 21E-03 1.10E-01 O.OOE+OO 1.SSE-04 1. 13E-Ol 

4.00E+02 2.3SE-03 9.9SE-02 O.OOE+OO 1.3SE-04 1.02E-0l 

S.00E+02 2.5SE-03 9.06E-02 O.OOE+OO 1.20E-04 9.32E-02 

6.00E+02 2. 71E-03 S.23E-02 O.OOE+OO 1.04E-04 S.SlE-02 

7.00E+02 2.S6E-03 7.49E-02 O.OOE+OO 9.09E-OS 7. 79E-02 

S.00E+02 3.00E-03 6.S3E-02 O.OOE+OO 7.91E-05 7. 14E-02 

9.00E+02 3. 14E-03 6. 23E-02 O.OOE+OO 6.S9E-OS 6.5SE-02 

1.00E+03 3. 26E-03 S.70E-02 O.OOE+OO 6.00E-OS 6.03E-02 

2.00E+03 3. 96E-03 2.SSE-02 O.OOE+OO 1.S0E-OS 2. 94E-02 

3.00E+03 3. 97E-03 1. 34E-02 O.OOE+OO 3.75E-06 1. 73E-02 

4.00E+03 3. 69E-03 S.2SE-03 O.OOE+OO 9.37E-07 1. 19E-02 

5.00E+03 3.31E-03 S.92E-03 O.OOE+OO 2.34E-07 9. 22E-03 

7.00E+03 2. 59E-03 4. 27E-03 O.OOE+OO 1.46E-OS 6.SSE-03 

S.00E+03 2. 29E-03 4.00E-03 O.OOE+OO O.OOE+OO 6. 29E-03 

9.00E+03 2.04E-03 3.S7E-03 O.OOE+OO O.OOE+OO S.91E-03 

1.00E+04 I.S2E-03 3.S0E-03 O.OOE+OO O.OOE+OO S.63E-03 

2.00E+04 7.1SE-04 3. 74E-03 O.OOE+OO O.OOE+OO 4.4SE-03 

B-3S7 
CLASS Y AHAD = 1 MICRON STABLE STRONTIUM 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------------------

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.00E-01 4. 19E-04 8.43E-05 

2.00E-01 5. 39E-04 3.05E-04 

3.00E-Ol 6. 36E-04 1. 17E-03 

4.00E-01 7. 38E-04 3. 19E-03 

5.00E-Ol 8.44E-04 6. 79E-03 

6.00E-01 9. 48E-04 1. 22E-02 

7.00E-Ol 1.05E-03 1. 95E-02 

S.OOE-01 1.l5E-03 2. 87E-02 

9.00E-Ol 1. 24E-03 3. 96E-02 

1.00E+OO 1. 34E-03 1. 34E-03 5.20E-02 5.20E-02 

2.00E+OO 7. 89E-04 2. 13E-03 1.59E-Ol 2.llE-OI 

3.00E+OO 6. 22E-04 2. 75E-03 1.30E-01 3. 41E-01 

4.00E+OO 5.09E-04 3.26E-03 7.29E-02 4.14E-Ol 

5.00E+OO 4. 22E-04 3. 68E-03 3. 61E-02 4.50E-Ol 

6.00E+OO 3. 54E-04 4.03E-03 1.71E-02 4.67E-01 

7.00E+OO 2. 99E-04 4. 33E-03 8.09E-03 4. 75E-01 

8.00E+OO 2. 55E-04 4. 59E-03 3. 89E-03 4. 79E-01 

9.00E+OO 2. 18E-04 4.8lE-03 1. 93E-03 4.8lE-Ol 

1.00E+Ol 1.87E-04 4. 99E-03 1.0lE-03 4.82E-Ol 

2.00E+Ol 5.07E-05 5. 94E-03 1. 43E-04 4. 84E-Ol 

3.00E+01 2. 32E-05 6. 26E-03 1.36E-04 4. 86E-Ol 

4.00E+Ol 1. 75E-05 6.45E-03 1. 33E-04 4. 87E-Ol 

5.00S+01 1. 63E-05 6.62E-03 1.31E-04 4. 88E-Ol 

6.00E+01 1. 59E-05 6. 78E-03 1. 29E-04 4.90E-01 

7.00E+01 1. 58E-05 6. 94E-03 1.27E-04 4.9lE-0l 

8.00E+Ol 1. 57E-05 7.10E-03 1. 26E-04 4. 92E-Ol 

9.00E+01 1. 56E-05 7. 25E-03 1.24E-04 4. 93E-01 

1.OOE+02 1. 56E-05 7.41E-03 1.22E-04 4. 95E-Ol 

2.00E+02 1. 52E-05 8. 95E-03 1.07E-04 5.06E-01 

3.00E+02 1.51E-OS 1.05E-02 9.32E-OS S.16E-Ol 

4.00E+02 1.50E-05 1.20E-02 8. 15E-05 5.25E-Ol 

5.00E+02 1.47E-05 1. 35E-02 7.12E-05 5. 32E-Ol 

6.00E+02 1. 45E-05 1.49E-02 6. 23E-05 5. 39E-Ol 

7.00E+02 1.41E-OS 1. 63E-02 5.45E-05 5.4SE-Ol 

8.00E+02 1.37E-05 1.77E-02 4.77E-05 5.S0E-01 

9.00E+02 1. 33E-05 1.91E-02 4.18E-05 5. 54E-Ol 

1.00E+03 1.29E-OS 2.04E-02 3. 66E-OS 5.S8E-01 

2.00E+03 8.l9E-06 3.09E-02 1.OOE-05 5. 79E-Ol 

3.00E+03 4. 74E-06 3. 72E-02 2.98E-06 5.8SE-01 

4.00E+03 2. 69E-06 4.08E-02 1.OlE-06 5. 86E-Ol 

5.00E+03 1. SSE-06 4. 29E-02 4.07E-07 5.87E-01 

7.00E+03 5.80E-07 4. 48E-02 1.llE-07 S.87E-01 

8.00E+03 3. 87E-07 4. 53E-02 7.03E-08 5.S8E-Ol 

9.00E+03 2. 75E-07 4. 56E-02 4.90E-OS 5. 88E-Ol 

1.OOE+04 2.07E-07 4. 59E-02 3.67E-08 5. 88E-Ol 

2.00E+04 5. 25E-08 4. 69E-02 O.OOE+OO 5. 88E-Ol 

B-388 
CLASS Y AHAD = 1 MICRON HALFLlFE== 1.06E+o4 DAYS STRONTIUM 90 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.50E-03 3.04E-01 2. 58E-Ol 7.30E-02 6.39E-Ol 

2.00E-Ol 3. 69E-03 2. 85E-Ol 2. 17E-Ol 1. 33E-Ol 6.38E-Ol 

3.00E-Ol 4.02E-03 2.70E-Ol 1.82E-Ol 1.81E-01 6. 37E-Ol 

4.00E-01 4.36E-03 2. 57E-Ol 1. 53E-Ol 2.20E-Ol 6. 35E-Ol 

5.00E-Ol 4. 68E';'03 2. 47E-01 1. 29E-01 2.51E-01 6. 31E-Ol 

6.00E-Ol 4. 95E-03 2. 38E-Ol 1.08E-Ol 2. 74E-Ol 6.26E-Ol 

7.00E-Ol 5. 17E-03 2. 31E-Ol 9. 12E-02 2.91E-01 6. 19E-Ol 

8.00E-Ol 5. 36E-03 2. 24E-Ol 7. 67E-02 3.03E-Ol 6.09E-Ol 

9.00E-01 5. 51E-03 2. 19E-Ol 6. 45E-02 3.10E-01 5. 98E-Ol 

1.00E+00 5. 62E-03 2. 13E-Ol 5. 42E-02 3. 13E-Ol 5. 86E-Ol 

2.00E+00 5. 78E-03 1.80E-01 9. 59E-03 2.30E-Ol 4.26E-Ol 

3.00E+00 5. 37E-03 1. 65E-Ol 1. 69E-03 1. 24E-Ol 2. 95E-Ol 

4.00E+00 4.90E-03 1. 57E-01 3.00E-04 6.00E-02 2.22E-Ol 

5.00E+00 4. 47E-03 1. 53E-Ol 5.30E-05 2. 82E-02 1. 85E-Ol 

6.00E1-00 4.10E-03 1.50E-01 9. 36E-06 1.33E-02 1.68E-Ol 

7.00E+00 3. 78E-03 1. 49E-Ol 1. 65E-06 6. 36E-03 1. 59E-Ol 

8.00E+00 3.50E-03 1.49E-Ol 2.93E-07 3. 14E-03 1. 55E-Ol 

9.00E+00 3. 27E-03 1.48E-Ol 5. 17E-08 1. 63E-03 1. 53E-Ol 

1.00E+Ol 3.07E-03 1.48E-Ol O.OOE+OO 9.10E-04 1.52E-Ol 

2.00E+Ol 2. 14E-03 1.46E-Ol O.OOE+OO 2. 34E-04 1.49E-Ol 

3.00E+Ol 1. 95E-03 1.45E-Ol O.OOE+OO 2.30E-04 1.47E-Ol 

4.00E+Ol 1.91E-03 1. 43E-Ol O.OOE+OO 2. 26E-04 1.45E-Ol 

5.00E+Ol 1.90E-03 1.42E-Ol O.OOE+OO 2.23E-04 1.44E-Ol 

6.00E+Ol 1.90E-03 1.40E-01 O.OOE+OO 2.20E-04 1. 42E-Ol 

7.00E+Ol 1.91E-03 1.38E-Ol O.OOE+OO 2. 17E-04 1.41E-Ol 

8.00E+Ol 1.91E-03 1.37E-Ol O.OOE+OO 2. 14E-04 1.39E-Ol 

9.00E+Ol 1.91E-03 1.35E-Ol O.OOE+oo 2. llE-04 1.38E-Ol 

1.00E+02 1. 92E-03 1. 34E-Ol O.OOE+OO 2.08E-04 1.36E-Ol 

2.00E+02 2.03E-03 1.20E-Ol O.OOE+oo 1.79E-04 1.22E-Ol 

3.00E+02 2. 17E-03 1.08E-Ol O.OOE+OO 1. 55E-04 1.IOE-Ol 

4.00E+02 2.32E-03 9.72E-02 O.OOE+oo 1.34E-04 9. 97E-02 

5.00E+02 2. 46E-03 8.77E-02 O.OOE+OO 1. 16E-04 9.02E-02 

6.00E+02 2.60E-03 7.91E-02 O.OOE+OO 1.00E-04 8. 18E-02 

7.00E+02 2. 73E-03 7. 15E-02 O.OOE+OO 8. 68E-05 7. 44E-02 

8.00E+02 2. 85E-03 6. 48E-02 O.OOE+oo 7. 51E-05 6.77E-02 

9.00E+02 2. 96E-03 5. 88E-02 O.OOE+OO 6.50E-05 6. 18E-02 

1.00E+03 3.05E-03 5. 34E-02 O.OOE+oo 5. 62E-05 5. 65E-02 

2.00E+03 3. 47E-03 2. 23E-02 O.OOE+OO 1. 32E-05 2. 58E-02 

3.00E+03 3.27E-03 1.IOE-02 O.OOE+oo 3.08E-06 1. 43E-02 

4.00E+03 2. 84E-03 6. 35E-03 O.OOE+OO 7. 22E-07 9. 19E-03 

5.00E+03 2. 39E-03 4. 27E-03 O.OOE+OO 1.69E-07 6. 65E-03 

7.00E+03 1. 64E-03 2.70E-03 O.OOE+OO O.OOE+OO 4. 34E-03 

8.00E+03 1. 36E-03 2. 37E-03 O.OOE+oo O.OOE+oo 3.73£-03 

9.00E+03 1. 13E-03 2. 15E-03 O.OOE+OO O.OOE+OO 3. 28E-03 

1.00E+04 9.48E-04 1.98E-03 O.OOE+OO O.OOE+OO 2.93E-03 

2.00E+04 1. 94E-04 1.01E-03 O.OOE+OO O.OOE+OO 1.20E-03 

B-389 
CLASS Y AMAD == 1 MICRON BALFLIFE- 1.06E+04 DAYS STRONTIUM 90 

TIME AFTER, FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 4.l9E-04 B.43E-05 

2.00E-Ol S.39E-04 3.05E-04 

3.00E-Ol 6.36E-04 1.17E-03 

4.00E-Ol 7.3SE-04 3.l9E-03 

S.OOE-Ol S.44E-04 6. 79E-03 

6.00E-Ol 9.4BE-04 1.22E-02 

7.00E-Ol I.OSE-03 1.9SE-02 

B.OOE-OI 1.ISE-03 2.S7E-02 

9.00E-Ol 1. 24E-03 3. 96E-02 

I.OOE+OO 1. 34E-03 1. 34E-03 5.20E-02 S.20E-02 

2.00E+OO 7.B9E-04 2.l3E-03 I.S9E-Ol 2.lIE-0l 

3.00E+OO 6.22E-04 2. 75E-03 1.30E-OI 3.4lE-OI 

4.00E+OO S.09E-04 3. 26E-03 7.29E-02 4.14E-OI 

5.00E+OO 4. 22E-04 3.6SE-03 3.6IE-02 4.50E-OI 

6.00E+OO 3. 54E-04 4.03E-03 1.7lE-02 4.67E-Ol 

7.00E+OO 2. 99E-04 4. 33E-03 B.09E-03 4. 75E-OI 

S.OOE+OO 2.S4E-04 4. SBE-03 3. BSE-03 4. 79E-OI 

9.00E+OO 2.IBE-04 4.S0E-03 1. 93E-03 4.81E-Ol 

I.OOE+Ol 1.S7E-04 4. 99E-03 I.OIE-03 4.B2E-OI 

2.00E+OI S.06E-OS S.93E-03 1.43E-04 4.B4E-OI 

3.00E+OI 2. 32E-OS 6.2SE-03 1.36E-04 4.B5E-OI 

4.00E+Ol 1.7SE-OS 6. 43E-03 1. 33E-04 4. 86E-Ol 

S.OOE+Ol 1. 62E-05 6.60E-03 1.3lE-04 4. 87E-Ol 

6.00E+Ol I.S9E-05 6. 75E-03 1. 29E-04 4. 88E-Ol 

7.00E+OI 1. 57E-05 6.9lE-03 1.27E-04 4.B9E-OI 

8.00E+OI 1. 56E-OS 7.06E-03 1.2SE-04 4.90E-OI 

9.00E+OI 1.55E-05 7.2IE-03 1.23E-04 4.9i"E-OI 

I.OOE+02 1.5SE-OS 7.36E-03 1.2IE-04 4.9lE-Ol 

2.00E+02 1.50E-05 S.S3E-03 1.05E-04 ,5.00E-Ol 

3.00E+02 1.4BE-05 1.03E-02 9.l4E-05 5.06E-OI 

4.00E+02 1.46E-05 1.17E-02 7. 94E-OS 5.l1E-0l 

5.00E+02 1. 43E-05 1.30E-02 6.S9E-OS 5.15E-Ol 

6.00E+02 1. 39E-05 1.43E-02 5.99E-05 5.lBE-OI 

7.00E+02 1. 35E-OS 1. 56E-02 S.,2lE-05 S.2IE-OI 

S.OOE+02 l.30E-OS 1.6SE-02 4. 53E-OS 5. 22E-Ol 

9.00E+02 1.26E-05 I.SOE-02 3. 94E-05 5. 23E-Ol 

1.00E+03 1.2IE-05 1.9lE-02 3. 43E-OS 5.23E-OI 

2.00E+03 7. ISE-06 2.71E-02 B.79E-06 S.08E-Ol 

3.00E+03 3.89E-06 3.06E-02 2.4SE-06 4.80E-OI 

4.00E+03 2.07E-06 3.14E-02 7.7SE-07 4.5IE-OI 

5.00E+03 1.12E-06 3.09E-02 2.93E-07 4.23E-0l 

7.00E+03 3. 67E-07 2. 84E-02 7.00E-08 3. 72E-Ol 

8.00E+03 2. 29E-07 2. 68E-02 4.l7E-08 3. 48E-Ol 

9.00E+03 1.S3E-07 2. 53E-02 2.12E-08 3. 26E-Ol 

1.OOE+04 1.OSE-07 2. 38E-02 1.9IE-08 3.06E-OI 

2.00E+04 1. 42E-OS 1.27E-02 O.OOE+OO 1.'59E-Ol 

B-390 
CLASS Y AMAD = 1 MICRON HALFLIFE= 5.85E+01 DAYS YTTRIUM 91 

TI~lE AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 69E-03 3.04E-Ol 2.5SE-0l 7.30E-02 6. 38E-Ol 

2.00E-Ol 3.5IE-03 2.S4E-Ol 2.16E-Ol 1.33E-Ol 6.37E-Ol 

3.00E-Ol 3. 37E-03 2. 69E-Ol 1. B2E-0l 1. BlE-Ol 6.3SE-OI 

4.00E-Ol 3. 26E-03 2.S6E-Ol 1. 53E-OI 2.20E-Ol 6. 32E-Ol 

5.00E-OI 3.lSE-03 2. 46E-OI 1.2BE-Ol 2.5IE-0l 6.2SE-OI 

6.00E-Ol 3.12E-03 2. 37E-Ol 1.OBE-Ol 2. 74E-Ol 6.22E-OI 

7.00E-0l 3.0BE-03 2. 29E-Ol 9.0SE-02 2.9lE-Ol 6.l4E-Ol 

B.OOE-Ol 3.04E-03 2. 22E-Ol 7.60E-02 3.03E-Ol 6.04E-Ol 

9.00E-Ol 3.02E-03 2.16E-Ol 6.38E-02 3.09E-Ol S.92E-Ol 

1.OOE+OO 2. 99E-03 Z.llE-Ol S.36E-02 3.l2E-Ol S.79E-Ol 

2.00E+OO 2.92E-03 l.76E-Ol 9. 37E-03 2.27E-Ol 4.lSE-OI 

3.00E+OO 2.90E-03 I.59E-OI I.64E-03 1.2IE-OI 2. 84E-OI 

4.00E+OO 2. 87E-03 I.49E-OI 2.B6E-04 S.79E-02 2.11E-OI 

5.00E+OO 2. BSE-03 I.44E-Ol 4. 99E-OS 2. 69E-02 1. 74E-Ol 

6.00E+OO 2.B3E-03 1.40E-Ol B.72E-06 1.25E-02 I.S6E-Ol 

7.00E+OO 2.BIE-03 1. 38E-OI I.S2E-06 S.93E-03 1.46E-OI 

8.00E+OO 2.79E-03 1.3SE-OI 2.66E-07 2.S9E-03 1.4lE-OI 

9.00E+OO 2.77E-03 1. 33E-OI 4.6SE-08 1.4BE-03 1. 38E-Ol 

1.00E+Ol 2.7SE-03 1.32E-OI O.OOE+OO B.lBE-04 1.35E-0l 

2.00E+Ol 2.S4E-03 1. 16E-Ol O.OOE+OO I.B6E-04 1.IBE-OI 

3.00E+Ol 2.3SE-03 1.02E-OI O.OOE+OO 1.63E-04 1.04E-OI 

4.00E+Ol 2. 17E-03 B.93E-02 O.OOE+OO 1. 43E-04 9.l6E-02 

5.00E+Ol 2.00E-03 7. BSE-02 O.OOE+OO I.2SE-04 B.06E-02 

6.00E+OI I.B4E-03 6.90E-02 O.OOE+OO 1.10E-04 7.lOE-02 

7.00E+OI 1. 69E-03 6.07E-02 O.OOE+OO 9.S9E-05 6.25E-02 

8.00E+OI 1.56E-03 S.34E-02 O.OOE+OO S.40E-05 S.SOE-02 

9.00E+Ol I.43E-03 4.69E-02 O.OOE+OO 7.36E-OS 4.B4E-02 

I.OOE+02 I.31E-03 4.l2E-02 O.OOE+OO 6.4SE-OS 4.26E-02 

2.00E+02 S.2SE-04 1. 14E-02 O.OOE+OO 1.72E-OS 1.19E-02 

3.00E+02 2.01E-04 3.I5E-03 O.OOE+OO 4.S7E-06 3. 36E-03 

4.00E+02 7.37E-OS B.73E-04 O.OOE+OO 1.22E-06 9.4BE-04 

S.OOE+02 2. 62E-OS 2. 42E-04 O.OOE+OO 3. 24E-07 2.69E-04 

6.00E+02 9.14E-06 6. 74E-OS O.OOE+OO B.63E-OB 7. 66E-OS 

7.00E+02 3.13E-06 I.8BE-OS O.OOE+OO 2.30E-OB 2.I9E-OS 

8.00E+02 1.06E-06 5.23E-06 O.OOE+OO O.OOE+OO 6.2SE-06 

9.00E+02 3.S3E-07 1. 46E-06 O.OOE+OO O.OOE+OO I.S1E-06 

1.00E+03 1. 17E-07 4.0BE-07 O.OOE+OO O.OOE+OO S.2SE-07 

B-39l 
CLASS Y AMAD = 1 KICRON IlALFLIFE= 5.85E+01 DAYS Y'lTRIUM. 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------~-----------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.0SE-04 1.04E-OS 

2.00E-Ol 3.9lE-04 2.l0E-04 

3.00E-Ol S.32E-04 1.OSE-03 

4.00E-Ol 6. 38E-04 3.06E-03 

S.OOE-Ol 7.l9E-04 6. 63E-03 

6.00E-Ol 7.80E-04 1.20E-02 

7.00E-Ol 8. 27E-04 1.93E-02 

8.00E-Ol 8. 62E-04 2. 84E-02 

9.00E-Ol 8.89E-04 3.92E-02 

1.00E+OO 9.09E-04 9.09E-04 S.lSE-02 S.lSE-02 

2.00E+OO 6.67E-OS 9.6SE-04 1.S7E-Ol 2.08E-0l 

3.00E+OO 9.06E-06 9. 63E-04 1. 26E-Ol 3. 32E-Ol 

4.00E+OO 4.77E-06 9. S6E-04 7.02E-02 3. 98E-Ol 

S.OOE+OO 4.Z6E-06 9.49E-04 3. 43E-02 4. 28E-Ol 

6.00E+OO 4.11E-06 9.42E-04 1.6lE-02 4. 39E-Ol 

7.00E+OO 4.02E-06· 9.3SE-04 7. 48E-03 4.4lE-Ol 

8.00E+OO 3. 96E-06 9. 28E-04 3. S3E-03 4. 39E-Ol 

9.00E+OO 3.9lE-06 9.21E-04 1.72E-03 4. 36E-Ol 

1.OOE+Ol 3. 86E-06 9.14E-04 8.7SE-04 4.32E-Ol 

2.00E+Ol 3. 44E-06 8. 46E-04 1.07E-04 3.8SE-Ol 

3.00E+Ol 3.07E-06 7.82E-04 9.32E-OS 3.43E-Ol 

4.00E+Ol 2. 74E-06 7. 22E-04 8.l7E-OS 3.06E-Ol 

S.OOE+Ol 2.44E-06 6. 66E-04 7.lSE-OS 2.72E-Ol 

6.00E+Ol 2.l8E-06 6.13E-04 6. 27E-OS 2.42E-Ol 

7.00E+Ol 1. 94E-06 S.64E-04 S.49E-05 2.l6E-0l 

8.00E+Ol 1. 73E-06 S.18E-04 4.8lE-05 1.92E-Ol 

9.00E+Ol 1.S4E-06 4.76E-04 4.2lE-OS 1.7lE-Ol 

1.00E+02 1. 37E-06 4. 36E-04 3. 69E-OS I.S2E-Ol 

2.00E+02 4. 29E-07 1. 76E-04 9. 83E-06 4.77E-02 

3.00E+02 1.32E-07 6.70E-OS 2. 62E-06 1. 49E-02 

4.00E+02 4.04E-08 2.4SE-OS 6. 97E-07 4.62E-03 

S.OOE+02 1. 22E-08 8. 74E-06 1. 86E-07 1.43E-03 

B-392 
CLASS Y AMAD = 1 MICRON STABLE ZIRCONIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.90E-03 3.04E-OI 2.S8E:"'OI 7.30E-02 6.39E-OI 

2.00E-OI 3.9SE-03 2.8SE-OI 2.17E-OI I.33E-OI 6.39E-OI 

3.00E-OI 4.02E-03 2.70E-OI 1. 82E-OI I.82E-OI 6. 38E-OI 

4.00E-OI 4. IOE-03 2.S7E-OI I.S3E-OI 2.2IE-OI 6.36E-OI 

S.OOE-Ol 4.16E-03 2.47E-OI I.29E-OI 2.S2E-0l 6.32E-0l 

6.00E-OI 4. 22E-03 2. 38E-OI I.08E-OI 2. 76E-OI 6.27E-OI 

7.00E-OI 4.27E-03 2.3IE-OI 9.12E-02 2.93E-OI 6.20E-OI 

8.00E-OI 4. 32E-03 2. 24E-OI 7.67E-02 3.0SE-OI 6. IOE-OI 

9.00E-Ol 4.3SE-03 2. 19E-Ol 6.4SE-02 3.12E-OI S.99E-Ol 

1.00E+OO 4.37E-03 2.l3E-01 S.42E-02 3.1SE-OI S.87E-OI 

2.00E+OO 4.40E-03 I.80E-OI 9.S9E-03 2. 32E-OI 4. 26E-OI 

3.00E+OO 4.29E-03 I.6SE-OI I.lOE-03 I.2SE-OI 2.9SE-OI 

4.00E+OO 4.1SE-03 1.S7E-OI 3.00E-04 6.06E-02 2.22E-Ol 

S.OOE+OO 4.02E-03 1.S3E-OI S.30E-OS 2.8SE-02 1.8SE-Ot 

6.00E+00 3.90E-03 1. SlE-OI 9. 37E-06 1. 34E-02 1.68E-OI 

7.00E+00 3. 78E-03 I.49E-OI 1. 66E-06 6. 42E-03 I.60E-OI 

8.00E+00 3. 68E-03 I.49E-OI 2.93E-07 3.17E-03 1. S6E-Ol 

9.00E+00 3.S9E-03 1. 48E-OI S.17E-08 1. 64E-03 I.S4E-Ol 

I.OOE+OI 3.S0E-03 I.48E-OI O.OOE+OO 9.19E-04 I.S3E-OI 

2.00E+OI 3.03E-03 I.46E-OI O.OOE+OO 2. 36E-04 I.SOE-Ol 

3.00E+OI 2.9IE-03 I.4SE-OI O.OOE+OO 2. 32E-04 1.48E-OI 

4.00E+OI 2.92E-03 I.43E-OI O.OOE+OO 2. 29E-04 I.47E-OI 

S.OOE+OI 2. 97E-03 I.42E-OI O.OOE+OO 2.26E-04 I.4SE-OI 

6.00E+OI 3.0SE-03 1.4IE-OI O.OOE+OO 2.236-04 I.44E-OI 

7.00E+OI 3.14E-03 I.39E-OI O.OOE+OO 2.I9E-04 I.42E-OI 

8.00E+OI 3.22E-03 1. 38E-Ol O.OOE+OO 2.16E-04 I.4IE-OI 

9.00E+OI 3.3IE-03 I.36E-OI O.OOE+OO 2.13E-04 I.40E-OI 

I.00E+02 3.40E-03 I.3SE-OI O.OOE+OO 2.11E-04 1. 38E-OI 

2.00E+02 4. 29E-03 I.22E-OI O.OOE+OO I.83E-04 I.26E-OI 

3.00E+02 S.IBE-03 1.lOE-OI O.OOE+OO I.60E-04 1. 16E-OI 

4.00E+02 6.06E-03 9. 98E-02 O.OOE+OO I.39E-04 I.06E-Ol 

S.OOE+02 6. 93E-03 9.06E-02 O.OOE+OO 1. 21E-04 9. 76E-02 

6.00E+02 7. 78E-03 8.23E-02 O.OOE+OO I.OSE-04 9.02E-02 

7.00E+02 8.6IE-03 7.49E-02 O.OOE+OO 9. 16E-05 8. 36E-02 

8.00E+02 9.40E-03 6.83E-02 O.OOE+OO 7.98E-OS 7. 78E-02 

9.00E+02 I.02E-02 6. 23E-02 O.OOE+OO 6. 94E-OS 7. 26E-02 

I.OOE+03 1.09E-02 S.70E-02 O.OOE+OO 6.0SE-OS 6. 79E-02 

2.00E+03 1. 61E-02 2.SSE-02 O.OOE+OO I.SIE-OS 4. 16E-02 

3.00E+03 1.83E-02 1. 34E-02 O.OOE+OO 3. 78E-06 3. 17E-02 . 

4.00E+03 I.86E-02 8.2SE-03 O.OOE+OO 9. 45E-07 2. 69E-02 

S.00E+03 I.8IE-02 S.92E-03 O.OOE+OO 2.36E-07 2.40E-02 

7.00E+03 I.S9E-02 4.27E-03 O.OOE+OO 1. 48E-08 2.02E-02 

8.00E+03 I.47E-02 4.00E-03 O.OOE+OO O.OOE+OO 1. 87E-02 

9.00E+03 1.3SE-02 3. 87E-03 O.OOE+OO O.OOE+OO 1. 74E-02 

1.00E+04 1.24E-02 3.80E-03 O.OOE+OO O.OOE+OO 1. 62E-02 

2.00E+04 S.2SE-03 3. 74E-03 O.OOE+OO O.OOE+OO 8. 99E-03 

B-393 
CLASS Y AHA» = 1 MICRON STABLE ZIRCONIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --------- 24-HOUR ACCUHULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.65E-05 1.04E-05 

2.00E-Ol 3. 58E-05 2.10E-04 

3.00E-Ol 5. 53E-05 1.06E-03 

4.00E-Ol 7.51E-05 3.07E-03 

5.00E-01 9. 52E-05 6.66E-03 

6.00E-Ol 1. 15E-04 1.21E-02 

7.00E-Ol 1.36E-04 1.94E-02 

8.00E-Ol 1.56E-04 2. 86E-02 

9.00E-Ol 1.77E-04 3. 95E-02 

1.00E+00 1. 98E-04 1. 98E-04 5.20E-02 5.20E-02 

2.00E+00 2.04E-04 4.02E-04 1.60E-01 2. 13E-Ol 

3.00E+00 1.91E-04 5.92E-04 1.31E-Ol 3. 43E-Ol 

4.00E+00 1. 76E-04 7. 68E-04 7.35E-02 4.17E-Ol 

5.00E+00 1.61£-04 9. 29E-04 3. 63E-02 4. 53E-Ol 

6.00E+00 1.47E-04 1.08E-03 1.72E-02 4.70E-Ol 

7.00E+00 1.34E-04 1 .. 21E-03 8.11E-03 4. 78E-Ol 

8.00E+00 1.22E-04 1.33E-03 3.88E-03 4.82E-Ol 

9.00E+00 1. llE-04 1.44E-03 1.91E-03 4.84E-Ol 

1.00E+Ol 1.02E-04 1. 54E-03 9.83E-04 4.85E-Ol 

2.00E+Ol 4. 35E-05 2.20E-03 1. 35E-04 4.87E-Ol 

3.00E+Ol 2. 19E-05 2. 49E-03 1.33E-04 4.89E-Ol 

4.00E+Ol 1. 39E-05 2. 66E-03 1.31E-04 4.90E-Ol 

5.00E+Ol 1.09E-05 2.78E-03 1.29E-04 4.91E-Ol 

7.00E+Ol 9. 49E-06 2. 98E-03 1. 26E-04 4. 94E-Ol 

8.00E+01 9.37E-06 3.08E-03 1.24E-04 4. 95E-Ol 

9.00E+Ol 9. 35E-06 3. 17E-03 1. 22E-04 4.96E-Ol 

1.00E+02 9.36E-06 3.26E-03 1.20E-04 4. 97E-Ol 

2.00E+02 9. 62E-06 4.21E-03 1.05E-04 5.09E-Ol 

3.00E+02 9. 78E-06 5. 18E-03 9. 13E-05 5. 18E-Ol 

4.00E+02 9. 84E-06 6. 17E-03 7. 95E-05 5. 27E-Ol 

5.00E+02 9. 82E-06 7.15E-03 6.92E-05 5.34E-Ol 

7.00E+02 9.60E-06 9.lOE-03 5. 24E-05 5. 46E-Ol 

8.00E+02 9. 43E-06 1.00E-02 4. 56E-05 5.51E-Ol 

9.00E+02 9. 22E-06 1.10E-02 3. 97E-05 5.56E-Ol 

1.00E+03 8. 99E-06 1. 19E-02 3.46E-05 5. 59E-01 

2.00E+03 6. 34E-06 I. 96E-02 8. 65E-06 5.78E-Ol 

3.00E+03 4.29E-06 2. 48E-02 2.16E-06 5.83E-01 

4.00E+03 3.02E-06 2. 84E-02 5.40E-07 5. 84E-Ol 

5.00E+03 2. 28E-06 3.1OE-02 1.35E-07 5.84E-Ol 

7.00E+03 1. 56E-06 3. 47E-02 O.OOE+OO 5. 84E-Ol 

8.00E+03 1. 36E-06 3. 62E-02 O.OOE+OO 5. 84E-01 

9.00E+03 1. 22E-06 3. 75E-02 O.OOE+OO 5. 84E-01 

1.00E+04 1.10E-06 3. 87E-02 O.OOE+OO 5. 84E-Ol 

2.00E+04 4. 55E-07 4. 59E-02 O.OOE+OO 5.84E-Ol 

B-394 
CLASS Y AHA» = 1 KICR.ON STABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 97E-03 3.04E-Ol 2.5BE-0l 7.30E-02 6. 39E-Ol 

2.00E-Ol 4.2BE-03 2.B5E-01 2.17E-01 1. 33E-Ol 6.39E-Ol 

3.00E-0l 4.70E-03 2.70E-Ol 1. B2E-0l 1. B1E-0l 6.3BE-01 

4.00E-01 5. 13E-03 2.57E-01 1.53E-Ol 2.20E-01 6.36E-Ol 

5.00E-01 5. 54E-03 2.47E-OI 1. 29E-01 2.51E-0l 6.32E-Ol 

6.00E-01 5.90E-03 2.3BE-01 1.0BE-Ol 2. 74E-Ol 6.27E-Ol 

7.00E-01 6.2lE-03 2.3lE-0l 9.l2E-02 2.9lE-0l 6.20E-Ol 

B.OOE-Ol 6.47E-03 2. 24E-Ol 7.67E-02 3.03E-Ol 6.lOE-Ol 

9.00E-Ol 6.70E-03 2.I9E-Ol 6. 45E-02 3.10E-Ol 6.00E-01 

1.OOE+OO 6.BBE-03 2.l3E-Ol 5. 42E-02 3. 13E-Ol 5.B7E-Ol 

2.00E+OO 7. 56E-03 1.BOE-Ol 9. 59E-03 2.30E-Ol 4. 27E-Ol 

3.00E+OO 7.4BE-03 1. 65E-01 1.70E-03 1.24E-Ol 2. 97E-Ol 

4.00E+OO 7. 24E-03 1.57E-0l 3.00E-04 6.00E-02 2. 24E-01 

5.00E+OO 6. 97E-03 1. 53E-Ol 5.30E-05 2.B3E-02 I.BBE-Ol 

6.00E+OO 6. 71E-03 1.5lE-0l 9. 37E-06 1. 33E-02 1.7lE-Ol 

7.00E+OO 6.46E-03 1.49E-Ol 1. 66E-06 6.37E-03 1. 62E-Ol 

B.OOE+OO 6. 24E-03 I.49E-01 2. 93E-07 3. 14E-03 1.5BE-Ol 

9.00E+OO 6.04E-03 I.4BE-01 S.l7E-OB 1. 63E-03 1.S6E-Ol 

1.00E+Ol 5.B5E-03 1.4BE-01 O.OOE+OO 9.11E-04 1. SSE-01 

2.00E+Ol 4.B1E-03 1.46E-01 O.OOE+OO 2. 34E-04 1.SIE-Ol 

3.00E+01 4. 44E-03 1.4SE-01 O.OOE+OO 2.30E-04 1.S0E-Ol 

4.00E+Ol 4. 29E-03 1.43E-01 O.OOE+OO 2. 27E-04 1.4BE-OI 

S.OOE+01 4.21E-03 1. 42E-01 O.OOE+OO 2. 24E-04 1.46E-OI 

6.00E+01 4. 16E-03 1.41E-01 O.OOE+OO 2. 21E-04 1.4SE-Ol 

7.00E+OI 4. 11E-03 1.39E-01 O.OOE+OO 2.1BE-04 1.43E-01 

B.OOE+01 4.07E-03 1.3BE-01 O.OOE+OO 2.1SE-04 ' 1.42E-Ol 

9.00E+Ol 4.02E-03 1.36E-01 O.OOE+OO 2. 12E-04 I.40E-01 

1.00E+02 3.9BE-03 I.3SE-01 O.OOE+OO 2.09E-04 1.39E-Ol 

2.00E+02 3. 66E-03 1.22E-01 O.OOE+OO I.B2E-04 1.26E-Ol 

3.00E+02 3. 43E-03 1.10E-01 O.OOE+OO 1.SBE-04 1. 14E-01 

4.00E+02 3. 27E-03 9.9BE-02 O.OOE+OO 1.3BE-04 1.03E-0l 

S.OOE+02 3. 14E-03 9.06E-02 O.OOE+OO 1.20E-04 9.3BE-02 

6.00E+02 3.03E-03 B.23E-02 O.OOE+OO 1.04E-04 B.S4E-02 

7.00E+02 2. 94E-03 7.49E-02 O.OOE+OO 9.09E-OS 7.79E-02 

B.OOE+02 2. BSE-03 6.B3E-02 O.OOE+OO 7.91E-OS 7.l2E-02 

9.00E+02 2. 76E-03 6. 23E-02 O.OOE+OO 6.B9E-OS 6.S2E-02 

1.00E+03 2. 67E-03 S. 70E-02 ' O.OOE+OO 6.00E-OS 5. 97E-02 'i 2.00E+03 1.12E-03 2.SSE-02 O.OOE+OO 1.50E-OS 2. 12E-02 

3.00E+03 9.6BE-04 1.34E-02 O.OOE+OO 3.7SE-06 1. 43E-02 

4.00E+03 S.1IE-04 B.2SE-03 O.OOE+OO 9. 37E-07 8. 76E-03 

S.OOE+03 2. 62E-04 S.92E-03 O.OOE+OO 2. 34E-07 6.1BE-03 

6.00E+03 1. 33E-04 4.B1E-03 O.OOE+OO S.B6E-OB 4. 94E-03 

7.00E+03 6.6BE-05 4. 27E-03 O.OOE+OO 1. 46E-OB 4.33E-03 

B.OOE+03 3. 35E-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.03E-03 

9.00E+03 1.6BE-05 3.B7E-03 O.OOE+OO O.OOE+OO 3.B9E-03 

1.OOE+04 B.39E-06 3. BOE-03 O.OOE+OO O.OOE+OO 3. BlE-03 

B-395 
CLASS Y AHAD = 1 MICRON STABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2.00E-05 1.04E-05 

2.00E-Ol 4. 44E-05 2.10E-04 

3.00E-Ol 7.09E-05 1.05E-03 

4.00E-Ol 9. 98E-05 3.06E-03 

5.00E-Ol 1. 31E-04 6. 64E-03 

6.00E-Ol 1. 64E-04 1.20E-02 

7.00E-Ol 2.00E-04 1. 93E-02 

8.00E-Ol 2.36E-04 2. 85E-02 

9.00E-Ol 2. 74E-04 3. 93E-02 

1.00E+00 3. 13E-04 3. 13E-04 5. 17E-02 5. 17E-02 

2.00E+00 4.11E-04 7. 25E-04 1. 59E-Ol 2.11E-Ol 

3.00E+00 4.02E-04 1. 13E-03 1.30E-Ol 3.41E-Ol 

4.00E+00 3. 71E-04 1.50E-03 7.28E-02 4. 13E-Ol 

5.00E+00 3. 37E-04 1. 83E-03 3.60E-02 4. 49E-Ol 

6.00E+00 3.05E-04 2. 14E-03 1.71E-02 4. 66E-Ol 

7.00E+00 2. 75E-04 2.41E-03 8.04E-03 4. 74E-Ol 

8.00E+00 2. 48E-04 2. 66E-03 3. 84E-03 4. 78E-Ol 

9.00E+00 2. 24E-04 2. 89E-03 1. 89E-03 4.80E-Ol 

1.00E+Ol 2.02E-04 3.09E-03 9.75E-04 4.81E-Ol 

2.00&+01 7.99E-05 4. 32E-03 1. 34E-04 4. 83E-Ol 

3.00E+Ol 4. 15E-05 4. 88E-03 1.32E-04 4. 85E-Ol 

4.00E+Ol 2. 94E-05 5. 21E-03 1.30E-04 4. 86E-Ol 

5.00E+01 2. 55E-05 5. 48E-03 1.28E-04 4. 87E-Ol 

6.00E+Ol 2.41E-05 5. 73E-03 1.26E-04 4. 88E-Ol 

7.00E+Ol 2. 36E-05 5. 97E-03 1.25E-04 4.90E-Ol 

8.00E+Ol 2. 34E-05 6.20E-03 1. 23E-04 4. 91E-Ol 

9.00E+Ol 2. 32E-05 6.43E-03 1.21E-04 4.92E-Ol 

1.00E+02 2.31E-05 6.67E-03 1.19E-04 4.93E-Ol 

2.00E+02 2.21E-05 8. 92E-03 1.04E-04 5.05E-Ol 

3.00E+02 2. 13E-05 1. 11E-02 9.06E-05 5. 14E-Ol 

4.00E+02 2.07E-05 1. 32E-02 7. 88E-05 5. 23E-Ol 

5.00E+02 2.01E-05 1.52E-02 6. 86E-05 5.30E-Ol 

7.00E+02 1.90E-05 1.91E-02 5.20E-05 5.42E-Ol 

8.00E+02 1. 84E-05 2.10E-02 4. 53E-05 5.47E-01 

9.00E+02 1. 78E-05 2.28E-02 3. 94E-05 5.51E-Ol 

1.00E+03 1.72E-05 2.46E-02 3. 43E-05 5. 55E-Ol 

2.00E+03 1.08E-05 3.86E-02 8.58E-06 5. 73E-Ol 

3.00E+03 5. 99E-06 4. 68E-02 2. 14E-06 5. 78E-Ol 

4.00E+03 3. 14E-06 5. 12E-02 5.36E-07 5. 79E-Ol 

5.00E+03 1.61E-06 5.35E-02 1. 34E-07 5. 79E-Ol 

7.00E+03 4.09E-07 5. 53E-02 O.OOE+OO 5.80E-01 

8.00E+03 2.05E-07 5.56E-02 O.OOE+OO 5.80E-01 

9.00E+03 1.03E-07 5. 57E-02 O.OOE+OO 5.80E-Ol 

1.00E+04 5. 13E-08 5. 58E-02 O.OOE+OO 5.80E-Ol 

B-396 
CLASS Y AHAD = 1 MICRON HALFUFE= 3.52E+Ol DAYS NIOBIUM 95 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 96E-03 3.04E-Ol 2. 58E-Ol 7.28E-02 6. 38E-Ol 

2.00E-Ol 4. 26E-03 2.84E-Ol 2. 16E-Ol 1. 32E-Ol 6.36E-Ol 

3.00E-Ol 4. 67E-03 2. 68E-Ol 1.81E-Ol 1.80E-Ol 6.34E-01 

4.00E-Ol 5.09E-03 2. 55E-Ol 1. 52E-Ol 2. 18E-Ol 6. 31E-01 

5.00E-Ol 5. 48E-03 2.45E-Ol 1. 28E-Ol 2. 48E-Ol 6.26E-Ol 

6.00E-Ol 5. 83E-03 2. 36E-Ol 1.07E-Ol 2.71E-Ol 6.20E-Ol 

7.00E-Ol 6. 13E-03 2.28E-Ol 9.00E-02 2.87E-Ol 6. 11E-Ol 

8.00E-Ol 6. 37E-03 2.21E-Ol 7. 55E-02 2.98£-01 6.01E-Ol 

9.00E-01 6.58£-03 2. 15E-01 6. 34E-02 3.04E-Ol 5.89£-01 

1.00E+00 6.74£-03 2.09£-01 5. 32E-02 3.06E-Ol 5.76£-01 

2.00£+00 7.27£-03 1.73E-01 9.22E-03 2.21E-Ol 4.11£-01 

3.00£+00 7.05E-03 1.55E-Ol 1.60E-03 1. 17E-Ol 2.80E-Ol 

4.00E+00 6. 69E-03 1.45E-Ol 2. 77E-04 5.55E-02 2.07E-Ol 

5.00E+00 6.31E-03 1.38E-Ol 4.80E-05 2. 56E-02 1.70E-Ol 

6.00E+00 5.96E-03 1.34E-Ol 8. 32E-06 1. 18E-02 1.52£-01 

7.00E+00 5. 63E-03 1.30E-Ol 1. 44E-06 5. 55E-03 1.41E-Ol 

8.00E+00 5. 33E-03 1.27E-Ol 2.50E-07 2.68E-03 1.35£-01 

9.00£+00 5.05E-03 1.24E-Ol 4. 33E-08 1. 36E-03 1.31£-01 

1.00E+Ol 4.81E-03 1.22E-Ol O.OOE+OO 7.48E-04 1.27£-01 

2.00£+01 3.24E-03 9.87E-02 O.OOE+OO 1. 58E-04 1.02£-01 

).OOE+Ol 2.46E-03 8.02E-02 O.OOE+OO 1.27E-04 8.28E-02 

4.00£+01 1.95E-03 6. 52E-02 O.OOE+OO 1.03E-04 6.72£-02 

5.00E+Ol 1.57E-03 5.30E-02 O.OOE+OO 8. 35E-05 5. 46E-02 

6.00E+Ol 1.27E-03 4.30E-02 O.OOE+OO 6. 76E-05 4. 44E-02 

7.00E+01 1.03E-03 3.50E-02 O.OOE+OO 5.48E-05 3.61E-02 

8.00E+01 8. 39E-04 2.84E-02 O.OOE+OO 4. 43E-05 2. 93E-02 

9.00E+Ol 6. 82E-04 2.31E-02 O.OOE+OO 3.59E-05 2. 38E-02 

1.00E+02 5. 54E-04 1. 88E-02 O.OOE+OO 2. 91E-05 1. 94E-02 

2.00E+02 7.08E-05 2. 36E-03 O.OOE+oo 3. 52E-06 2.43£-03 

3.00E+02 9. 25E-06 2.97E-04 0.00£+00 4. 27E-07 3.07E-04 

4.00E+02 1.23E-06 3.75E-05 O.OOE+oo 5. 17E-08 3. 87E-05 

5.00E+02 1. 64E-07 4. 73E-06 O.OOE+OO O.OOE+OO 4. 89E-06 

6.00E+02 2.21E-08 5. 98E-07 O.OOE+oo O.OOE+OO 6.20E-07 

B-397 
CLASS Y AHA» ,.. 1 MICRON HALFLIFE= 3.52£+01 DAYS NIOBIUM 95 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2.00E-05 1.04E-05 

2.00E-Ol 4.42E-05 2.09E-04 

3.00E-Ol 7.05E-05 1.05E-03 

4.00E-Ol 9.90E-05 3.04E-03 

5.00E-01 1.30E-04 6. 57E-03 

6.00E-Ol 1. 63E-04 1. 19E-02 

7.00E-Ol 1. 97E-04 1.91E-02 

8.00E-01 2. 33E-04 2.80E-02 

9.00E-01 2.70E-04 3. 86E-02 

1.00E+00 3.07E-04 3.07E-04 5.07E-02 5.07E-02 

2.00E+00 3. 95E-04 6.97E-04 1.53E-01 2.03E-Ol 

3.00E+00 3. 79E-04 1.06E-03 1.22E-01 3.21E-Ol 

4.00E+00 3. 43E-04 1.38E-03 6. 73E-02 3. 82E-Ol 

5.00E+00 3.06E-04 1. 66E-03 3. 26E-02 4.07E-01 

6.00E+00 2. 71E-04 1.90E-03 1. 52E-02 4.14E-01 

7.00E+00 2.40E-04 2.lOE-03 7.00E-03 4. 13E-01 

8.00E+00 2.12E-04 2.27E-03 3.28E-03 4.08E-Ol 

9.00E+00 1.87E-04 2.42E-03 1. 58E-03 4.02E-01 

1.00E+01 1. 66E-04 2. 54E-03 8.00E-04 3.95E-Ol 

2.00E+Ol 5. 39E-05 2.91E-03 9.05E-05 3.26E-Ol 

3.00E+Ol 2.30E-05 2.70E-03 7.29E-05 2. 68E-01 

4.00E+01 1. 33E-05 2.37E-03 5.90E-05 2.21E-01 

5.00E+Ol 9.50E-06 2.05E-03 4. 78E-05 1.82E-Ol 

6.00E+Ol 7.40E-06 1.75E-03 3. 87E-05 1.50E";"01 

7.00E+Ol 5.95E-06 1.50E-03 3. 13E-05 1. 23E-01 

8.00E+01 4.83E-06 1.28E-03 2. 54E-05 1.01E-01 

9.00E+01 3. 94E-06 1.09E-03 2.05E-OS 8. 34E-02 

1.00E+02 3. 22E-06 9. 28E-04 1. 66E-05 6.87E-02 

2.00E+02 4.28E-07 .1.73E-04 2.02E-06 9. 77E-03 

3.00E+02 5.75E-08 2. 99E-05 2. 44E-07 1. 39E-03 

B-398 
CLASS Y AHAD = 1 MICRON STABLE MOLYBDERUK 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 4. 36E-03 3.04E-01 2. S8E-01 7. 26E-02 6. 39E-01 

2.00E-01 6.00E-03 2.8SE-01 2.l7E-OI 1.3IE-Ol 6. 39E-01 

3.00E-OI 8.20E-03 2.70E-Ol 1.82E-Ol 1.77E-Ol 6. 38E-Ol 

4.00E-01 1.OSE-02 2.S7E-Ol 1.S3E-Ol 2.1SE-01 6.36E-01 

S.OOE-Ol 1. 26E-02 2.47E-Ol 1. 29E-01 2.44E-01 6.32E-01 

6.00E-01 1. 44E-02 2. 38E-01 1.08E-01 2. 66E-Ol 6.27E-Ol 

7.00E-01 1.61E-02 2. 31E-0l 9. 12E-02 2. 82E-01 6.20E-Ol 

8.00E-Ol 1. 74E-02 2. 24E-01 7. 67E-02 2. 92E-01 6.11E-01 

9.00E-Ol 1. 86E-02 2. 19E-0l 6.4SE-02 2. 98E-Ol 6.00E-01 

1.00E+OO 1. 96E-02 2.DE-Ol S.42E-02 3.0IE-OI S.88E-Ol 

2.00E+OO 2. 37E-02 1.80E-Ol 9.S9E-03 2.20E-0l 4.34E-01 

3.00E+OO 2. 44E-02 1.6SE-OI 1.70E-03 I. 18E-Ol 3.09E-01 

4.00E+OO 2. 43E-02 1. 57E-01 3.00E-04 5. 73E-02 2.39E-Ol 

S.OOE+OO 2.40E-02 I.S3E-Ol S.30E-OS 2.70E-02 2.04E-Ol 

6.00E+OO 2. 37E-02 1. SIE-Ol 9. 37E-06 1.27E-02 I.87E-Ol 

7.00E+OO 2.34E-02 1.49E-Ol 1. 66E-06 6.08E-03 1. 79E-Ol 

8.00E+OO 2. 31E-02 1. 49E-0l 2. 93E-07 3.00E-03 1.7SE-01 

9.00E+OO 2. 28E-02 1. 48E-Ol S.17E-08 1.S6E-03 1. 73E-Ol 

1.00E+Ol 2.2SE-02 1.48E-Ol O.OOE+OO 8. 71E-04 1.72E-Ol 

2.00E+Ol 1. 98E-02 1.46E-Ol O.OOE+OO 2.2SE-04 1. 67E-01 

3.00E+Ol 1.7SE-02 1.4SE-Ol O.OOE+OO 2.21E-04 1.63E-Ol 

4.00E+Ol I.S4E-02 1.43E-Ol O.OOE+OO 2. 18E-04 1.S9E-Ol 

S.OOE+Ol 1.36E-02 1.42E-Ol O.OOE+OO 2.1SE-04 1. S6E-01 

6.00E+Ol 1. 21E-02 1.41E-Ol O.OOE+OO 2. 12E-04 1. 53E-01 

7.00E+01 1.07E-02 1.39E-Ol O.OOE+OO 2.09E-04 1. SOE-01 

8.00E+Ol 9. 52E-03 1. 38E-Ol O.OOE+OO 2.06E-04 1.47E-Ol 

9.00E+01 8. 49E-03 1.36E-0l O.OOE+OO 2.03E-04 1.4SE-01 

1.00E+02 7.S9E-03 1.3SE-Ol O.OOE+OO 2.01E-04 1.43E-Ol 

2.00E+02 3.06E-03 1.22E-Ol O.OOE+OO 1.7SE-04 1.25E-Ol 

3.00E+02 1.90E-03 1.10E-01 O.OOE+OO 1.S2E-04 1. 12E-Ol 

4.00E+02 1. S8E-03 9. 98E-02 O.OOE+OO 1.32E-04 1.02E-Ol 

S.OOE+02 1.47E-03 9.06E-02 O.OOE+OO 1.1SE-04 9. 22E-02 

6.00E+02 1.41E-03 8. 23E-02 O.OOE+OO 1.00E-04 8.38E-02 

7.00E+02 1.3SE-03 7. 49E-02 O.OOE+OO 8. BE-OS 7. 63E-02 

8.00E+02 1.30E-03 6.83E-02 O.OOE+OO 7.60E-OS 6.97E-02 

9.00E+02 1.2SE-03 6. 23E-02 O.OOE+OO 6.62E-OS 6. 36E-02 

1.00E+03 1. 19E-03 S.70E-02 O.OOE+OO S.76E-OS S.83E-02 

2.00E+03 6. 97E-04 2.SSE-02 O.OOE+OO 1. 44E-OS 2. 62E-02 

3.00E+03 3. 74E-04 1.34E-02 O.OOE+OO 3.60E-06 1. 38E-02 

4.00E+03 1. 93E-04 8.2SE-03 O.OOE+OO 9.00E-07 8. 44E-03 

S.OOE+03 9.82E-05 S.92E-03 O.OOE+OO 2.2SE-07 6.01E-03 

6.00E+03 4.9SE-OS 4. 81E-03 'O.OOE+OO S.63E-08 4. 86E-03 

7.00E+03 2. 49E-OS 4. 27E-03 O.OOE+OO 1.41E-08 4.29E-03 

8.00E+03 1.2SE-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.01E-03 

9.00E+03 6. 23E-06 3.87E-03 O.OOE+OO O.OOE+OO 3. 88E-03 

I.OOE+04 3. 12E-06 3.80E-03 O.OOE+OO O.OOE+OO 3. 81E-03 

B-399 
CLASS Y AMAD = 1 MICRON STABLE MOLYBDENUM 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 78E-05 1.04E-05 

2.00E-Ol 6.72E-05 2.08E-04 

3.00E-Ol 1.20E-04 1.04E-03 

4.00E-Ol 1.89E-04 3.02E-03 

5.00E-01 2.72E-04 6. 52E-03 

6.00E-Ol 3. 67E-04 1. 18E-02 

7.00E-Ol 4.71E-04 1.89E-02 

8.00E-Ol 5. 82E-04 2.78E-02 

9.00E-01 6. 99E-04 3. 83E-02 

1.00E+00 8. 18E-04 8. 18E-04 5.03E-02 5.03E-02 

2.00E+00 1. 15E-03 1.97E-03 1. 53E-Ol 2.04E-Ol 

3.00E+00 8. 93E-04 2.87E-03 1. 24E-Ol 3. 27E-Ol 

4.00E+00 6.61E-04 3. 53E-03 6.95E-02 3.97E-Ol 

5.00E+00 5. 15E-04 4.04E-03 3. 44E-02 4. 31E-Ol 

6.00E+00 4.31E-04 4.47E-03 1.63E-02 4.48E-Ol 

7.00E+00 3. 82E-04 4.85E-03 7.67E-03 4. 55E-Ol 

8.00E+00 3. 53E-04 5.21E-03 3.66E-03 4. 59E-Ol 

9.00E+00 3. 36E-04 5. 54E-03 1.80E-03 4.61E-Ol 

1.00E+Ol 3.25E-04 5. 87E-03 9. 31E-04 4.62E-Ol 

2.00E+Ol 2. 79E-04 8.83E-03 1. 29E-04 4.64E-Ol 

3.00E+Ol 2.46E-04 1.14E-02 1. 26E-04 4.65E-Ol 

4.00E+Ol 2. 17E-04 1.37E-02 1. 25E-04 4. 66E-Ol 

5.00E+Ol 1.92E-04 1. 58E-02 1.23E-04 4.68E-Ol 

6.00E+Ol 1.71E-04 1. 76E-02 1.21E-04 4. 69E-Ol 

7.00E+Ol 1. 52E-04 1.92E-02 1.20E-04 4.70E-Ol 

8.00E+Ol 1. 35E-04 2.06E-02 1. 18E-04 4.71E-Ol 

9.00E+Ol 1.21E-04 2. 19E-02 1.16E-04 4. 72E-Ol 

1.00E+02 1.08E-04 2.30E-02 1. 15E-04 4. 73E-Ol 

2.00E+02 4.48E-05 2. 99E-02 9. 98E-05 4.84E-Ol 

3.00E+02 2. 86E-05 3. 34E-02 8. 69E-05 4. 93E-Ol 

4.00E+02 2.41E-05 3.60E-02 7.56E-05 5.02E-Ol 

5.00E+02 2. 25E-05 3. 83E-02 6. 59E-05 5.09E-Ol 

7.00E+02 2.07E-05 4.26E-02 4. 99E-05 5.20E-Ol 

8.00E+02 1. 99E-05 4.47E-02 4. 34E-05 5.25E-Ol 

9.00E+02 1.91E-05 4. 66E-02 3. 78E-05 5.29E-Ol .. 1.00E+03 1.83E-05 4.85E-02 3. 29E-05 5. 32E-Ol 

2.00E+03 1.07E-05 6.28E-02 8.23E-06 5.50E-Ol 

3.00E+03 5. 72E-06 7.07E-02 2.06E-06 5. 55E-Ol 

4.00E+03 2. 96E-06 7. 49E-02 5.14E-07 5.56E-Ol 

5.00E+03 1.50E-06 7. 71E-02 1.29E-07 5. 56E-Ol 

7.00E+03 3.80E-07 7. 87E-02 O.OOE+OO 5. 56E-Ol 

8.00E+03 1.90E-07 7.90E-02 O.OOE+OO .5. 56E-Ol 

9.00E+03 9. 53E-08 7.91E-02 O.OOE+OO 5. 56E-Ol 

1.00E+04 4. 77E-08 7. 92E-02 O.OOE+OO 5. 56E-Ol 

B-400 
CLASS Y AHA» = 1 KICRON STABLE RtrrHENIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 4. 27E-03 3.04E-Ol 2. S8E-0l 7. 26E-02 6.39E-0l 

2.00E-Ol S.79E-03 2.8SE~Ol 2.l7E-Ol 1.31E-01 6. 39E-01 

3.00E-01 7. 84E-03 2.70E-Ol 1. 82E-Ol 1. 77E-Ol 6. 38E-Ol 

4.00E-Ol 9. 93E-03 2.S7E-01 1.S3E-01 2.lSE-Ol 6.3SE-Ol 

S.OOE-01 1.18E--02 2.47E-01 1.29E-01 2. 44E-Ol 6.32E-01 

6.00E-01 1.3SE-02 2.3BE-Ol 1.08E-Ol 2. 66E-Ol 6. 26E-Ol 

7.00E-Ol 1.49E-02 2.3lE-0l 9. 12E-02 2.82E-Ol 6. 19E-Ol 

B.OOE-Ol 1.6lE-02 2. 24E-Ol 7. 67E-02 2. 92E-01 6.09E-01 

9.00E-Ol 1.71E-02 2.l9E-Ol 6.4SE-02 2.98E-01 S.99E-0l 

1.00E+OO 1.79E-02 2. 13E-01 S.42E-02 3.0lE-Ol S.86E-01 

2.00E+OO 2.lOE-02 1.80E-01 9. S9E-03 2.20E-01 4.3lE-Ol 

3.00E+OO 2. 12E-02 1.6SE-Ol 1.70E-03 1.lBE-O! 3.06E .... Ol 

4.00E+OO 2.08E-02 1. S7E-0l 3.00E-04 S.73E-02 2.3SE-01 

S.OOE+OO 2.02E-02 1. 53E-01 S.30E-OS 2.70E-02 2.00E-01 

6.00E+OO 1. 96E-02 1.SlE-0l 9.37E-06 1. 27E-02 1.B3E-Ol 

7.00E+OO 1.90E-02 1.49E-Ol 1.66E-06 6.0BE-03 1. 74E-01 

8.00E+OO 1.84E-02 1.49E-Ol 2.93E-07 3.00E-03 1.70E-Ol 

9.00E+OO 1. 78E-02 1.48E-Ol S.17E-OB 1.S6E-03 1.6BE-Ol 

1.00~+Ol 1.73E-02 1.4BE-Ol O.OOE+OO 8.7lE-04 1.'66E-01 

2.00E+01 1.3SE-02 1.46E-Ol O.OOE+OO 2.2SE-04 1.60E-01 

3.00E+01 1.1SE-02 1.45E-01 O.OOE+OO 2.2lE-04 1. S7E-0l 

4.00E+Ol 1.02E-02 1.43E-01 O.OOE+OO 2. 18E-04 1.S4E-01 

5.00E+Ol 9.3SE-03 1.42E-Ol O.OOE+OO 2.1SE-04 1.52E-Ol 

6.00E+01 8. 73E-03 1.41E-01 O.OOE+OO 2. 12E-04 1. 49E-01 

7.00E+01 8.25E-03 1.39E-01 O.OOE+OO 2.09E-04 1.48E-01 

8.00E+Ol 7.87E-03 1.3BE-Ol O.OOE+OO 2.06E-04 1. 46E-Ol 

9.00E+01 7. S7E-03 1.36E-01 O.OOE+OO 2.03E-04 1. 44E-01 

1.OOE+02 7.33E-03 1. 35E-01 O.OOE+OO 2.01E-04 1. 42E-Ol 

2.00E+02 6. 42E-03 1.22E-01 O.OOE+OO 1.7SE-04 1.2BE-01 

3.00E+02 6.34E-03 1.lOE-Ol O.OOE+OO 1. 52E-04 1.17E-Ol 

4.00E+02 6.3SE-03 9. 98E-02 O.OOE+OO 1.32E-04 1.06E-Ol 

S.OOE+02 6.37E-03 9.06E-02 O.OOE+OO 1.1SE-04 9.70E-02 

6.00E+02 6. 37E-03 B.23E-02 O.OOE+OO 1.00E-04 8.B8E-02 

7.00E+02 6.3SE-03 7.49E-02 O.OOE+OO 8.73E-OS 8. 13E-02 

8.00E+02 6. 32E-03 6.B3E-02 O.OOE+OO 7.60E-OS 7.47E-02 

9.00E+02 6. 27E-03 6. 23E-02 O •. OOE+OO 6. 62E-OS 6. 87E-02 , ...... ,. " 1.00E+03 6.2lE-03 S.70E-02 O.OOE+OO S.76E-OS 6. 33E-02 

2.00E+03 S.06E-03 2.S5E-02 O.OOE+OO 1. 44E-OS 3.0SE-02 

3.00E+03 3.60E-03 1.34E-02 O.OOE+OO 3.60E-06 1.70E-02 

4.00E+03 2. 36E-03 8. 25E-03 O.OOE+OO 9.00E-07 1.06E-02 

S.OOE+03 1. 47E-03 S.92E-03 O.OOE+OO 2.25E-07 7. 38E-03 

7.00E+03 5.11E-04 4. 27E-03 O.OOE+OO 1.4lE-OB 4. 78E-03 

8.00E+03 2.92E-04 4.00E-03 O.OOE+OO O.OOE+OO 4. 29E-03 

9.00E+03 1. 64E-04 3. 87E-03 O.OOE+OO O.OOE+OO 4.03E-03 

1.00E+04 9. 12E-05 3. BOE-03 O.OOE+OO O.OOE+OO 3.B9E-03 

2.00E+04 1. 78E-07 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-401 
CLASS Y AKA» = 1 KICRON STABLE RlITHENIUK 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUHULATED 24-HOUR ACCilllULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1.22E-04 1.04E-OS 

2.00E-Ol 2. 79E-04 2.08E-04 

3.00E-Ol 4. 76E-04 1.04E-03 

4.00E-Ol 7.l9E-04 3.02E-03 

S.OOE-Ol 9. 97E-04 6.S2E-03 

6.00E-Ol 1.30E-03 1.18E-02 

7.00E-Ol 1.6lE-03 1.89E-02 

8.00E-Ol 1. 92E-03 2.78E-02 

9.00E-Ol 2. 23E-03 3. 83E-02 

1.OOE+OO 2.S3E-03 2.S3E-03 S.03E-02 S.O~E-02 

2.00E+OO 2. 22E-03 4.7 SE-03 1. S3E-Ol 2.04E-Ol 

3.00E+OO 1.30E-03 6.0SE-03 1.24E-Ol 3.27E-Ol 

4.00E+OO 9.71E-04 7.03E-03 6.9SE-02 3.97E-Ol 

S.OOE+OO 8. 36E-04 7. 86E-03 3. 44E-02 4.3lE-Ol 

6.00E+OO 7. S6E-04 8. 62E-03 1.63E-02 4.48E-Ol 

7.00E+OO 6. 96E-04 9.3lE-03 7. 67E-03 4.SSE-Ol 

8.00E+OO 6.4SE-04 9. 96E-03 3. 66E-03 4.S9E-Ol 

9.00E+OO 6.0lE-04 1.06E-02 1.80E-03 4.6lE"':Ol 

1.OOE+Ol S.6lE-04 1.llE-02 9.3lE-04 4.62E-Ol 

2.00E+Ol 3.03E-04 1.SlE-02 1.29E-04 4.64E-Ol 

3.00E+Ol 1.8SE-04 1. 74E-02 1.26E-04 4.6SE-Ol 

4.00E+Ol 1. 28E-04 1. 89E-02 1.2SE-04 4. 66E-Ol 

S.OOE+Ol 9.70E-OS 2.00E-02 1.23E-04 4.68E-Ol 

6.00E+Ol 7.87E-OS 2.09E-02 1.2lE-04 4. 69E-Ol 

7.00E+Ol 6.66E-OS 2.l6E-02 1.20E-04 4.70E-Ol 

8.00E+Ol S.79E-OS 2. 22E-02 1.18E-04 4.7lE-Ol 

9.00E+Ol S.13E-OS 2.28E-02 1.16E-04 4.72E-Ol 

1.OOE+02 4.6lE-OS 2. 33E-02 1.lSE-04 4. 73E-Ol 

2.00E+02 2.6lE-OS 2. 66E-02 9.98E-OS 4. 84E-Ol 

3.00E+02 2.3lE-OS 2.90E-02 8. 69E-OS 4.93E-Ol 

4.00E+02 2. 22E-OS 3.l2E-02 7. S6E-OS S.02E-Ol 

S.OOE+02 2.l7E-OS 3. 34E-02 6.S9E-OS S.09E-Ol 

7.00E+02 2.04E-OS 3. 76E-02 4.99E-OS S.20E-Ol 

8.00E+02 1. 98E-OS 3. 96E-02 4. 34E-OS S.2SE-Ol 

9.00E+02 1.9lE-OS 4.l6E-02 3.78E-OS S.29E-Ol 

1.OOE+03 1. 84E-OS 4.3SE-02 3.29E-OS S.32E-Ol 

2.00E+03 1.17E-OS S.84E-02 8. 23E-06 S.SOE-Ol 

3.00E+03 6. 88E-06 6.7SE-02 2.06E-06 S.SSE-Ol 

4.00E+03 3.90E-06 7. 28E-02 S.14E-07 S.S6E-Ol 

S.OOE+03 2.l6E-06 7.S7E-02 1.29E-07 S.S6E-Ol 

7.00E+03 6.4SE-07 7.82E-02 O.OOE+OO S.S6E-Ol 

8.00E+03 3. 48E-07 7.87E-02 O.OOE+OO S.S6E-Ol 

9.00E+03 1.87E-07 7.90E-02 O.OOE+OO S.S6E-Ol 

1.OOE+04 9.97E-08 7.9lE-02 O.OOE+OO S.S6E-Ol 

B-402 
CLASS Y AHA» = 1 MICRON STABLE RHODIUM 103 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 4.27E-03 3.04E-Ol 2.s8E-Ol 7.26E-02 6.39E-OI 

2.00E-OI s.79E-03 2.8sE-OI 2.17E-OI 1.3IE-OI 6.39E-OI 

3.00E-OI 7.84E-03 2.70E-OI 1.82E-0l 1.77E-OI 6.38E-OI 

4.00E-OI 9.93E-03 2.57E-OI 1.53E-Ol 2.l5E-OI 6.35E-OI 

s.OOE-Ol 1.l8E-02 2.47E-Ol 1.29E-OI 2.44E-Ol 6.32E-OI 

6.00R-Ol l.3sE-02 2.38E-Ol I.OBE-Ol 2.66E-Ol 6.26E-OI 

7.00E-OI 1.49E-02 2.3lE-Ol 9.12E-02 2.82E-Ol 6.19E-Ol 

8.00E-Ol 1.6lE-02 2.24E-OI 7.67E-02 2.92E-Ol 6.09E-Ol 

9.00E-Ol 1.71E-02 2.l9E-Ol 6.45E-02 2.9SE-Ol 5.99E-OI 

1.OOE+OO 1.79E-02 2.l3E-Ol 5.42E-02 3.0lE-Ol 5.86E-Ol 

2.00E+OO 2.10E-02 1.SOE-Ol 9.59E-03 2.20E-OI 4.3lE-Ol 

3.00E+OO 2.l2E-02 1.6sE-Ol 1.70E-03 1.ISE-Ol 3.06E-Ol 

4.00E+OO 2.08E-02 1.57E-Ol 3.00E-04 s.73E-02 2.35E-Ol 

s.OOE+OO 2.02E-02 1.53E-OI s.30E-05 2.70E-02 2.00E-Ol 

6.00E+OO l.96E-02 1.5lE-Ol 9.37E-06 1.27E-02 1.S3E-Ol 

7.00E+OO 1.90E-02 1. 49E-Ol 1.66E-06 6.0SE-03 1.74E-Ol 

S.OOE+OO 1.B4E-02 1.49E-Ol 2.93E-07 3.00E-03 1.70E-Ol 

9.00E+OO 1.7BE-02 1.4BE-Ol 5.l7E-OS l.56E-03 1.6SE-Ol 

1.OOE+Ol 1.73E-02 l.48E-Ol O.OOE+OO B.7lE-04 1.66E-Ol 

2.00E+Ol 1.35E-02 1.46E-Ol O.OOE+OO 2.2sE-04 1.60E-Ol 

3.00E+Ol 1.15E-02 1.4sE-Ol O.OOE+OO 2.2lE-04 l.s7E-Ol 

4.00E+Ol 1.02E-02 1.43E-Ol O.OOE+OO 2.lSE-04 1.s4E-OI 

s.OOE+Ol 9.3sE-03 1.42E-Ol O.OOE+OO 2.lsE-04 1.52E-Ol 

6.00E+OI B.73E-03 1.41E-OI O.OOE+OO 2.12E-04 1.49E-OI 

7.00E+Ol 8.2sE-03 1.39E-Ol O.OOE+OO 2.09E-04 1.4SE-OI 

S.OOE+OI 7.B7E-03 1.38E-Ol O.OOE+OO 2.06E-04 1.46E-OI 

9.00E+OI 7.s7E-03 1.36E-Ol O.OOE+OO 2.03E-04 1.44E-Ol 

1.00E+02 7.33E-03 1.35E-01 O.OOE+OO 2.0IE-04 1.42E-Ol 

2.00E+02 6.42E-03 1. 22E-01 O.OOE+OO 1.75E-04 1.28E-01 

3.00E+02 6.34E-03 1.10E-01 O.OOE+OO 1.s2E-04 1.17E-Ol 

4.00E+02 6.35E-03 9.9SE-02 O.OOE+OO 1.32E-04 1.06E-Ol 

s.OOE+02 6.37E-03 9.06E-02 O.OOE+OO 1. 15E-04 9.70E-02 

6.00E+02 6.37E-03 S.23E-02 O.OOE+OO I.OOE-04 S.SSE-02 

7.00E+02 6.35E-03 7.49E-02 O.OOE+OO S.73E-Os S.13E-02 

S.OOE+02 6.32E-03 6.S3E-02 O.OOE+OO 7.60E-Os 7.47E-02 

9.00E+OZ 6.27E-03 6.23E-02 O.OOE+OO 6.62E-05 6.S7E-02 ~,' . ' " 1.00E+03 6.2lE-03 5.70E-02 O.OOE+OO 5.76E-05 6.33E-02 

2.00E+03 5.06E-03 2. 55E-02 O.OOE+OO 1.44E-05 3.05E-02 

3.00E+03 3.60E-03 1.34E-02 O.OOE+OO 3.60E-06 1.70E-02 

4.00E+03 2.36E-03 S.25E-03 O.OOE+OO 9.00E-07 1.06E-02 

5.00E+03 1.47E-03 s.92E-03 O.OOE+OO 2.25E-07 7.3SE-03 

7.00E+03 s.l1E-04 4.27E-03 O.OOE+OO 1.4IE-OS 4.7SE-03 

8.00E+03 2.92E-04 4.00E-03 O.OOE+OO O.OOE+OO 4.29E-03 

9.00E+03 1.64E-04 3.S7E-03 O.OOE+OO O.OOE+OO 4.03E-03 

1.OOE+04 9.l2E-Os 3.S0E-03 O.OOE+OO O.OOE+OO 3.S9E-03 

2.00E+04 1.78E-07 3.74E-03 O.OOE+OO O.OOE+OO 3.74E-03 

B-403 
CLASS Y AKAD = I MICRON STABLE RHODIUM 103 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

------------------------- ----------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.22E-04 I.04E-OS 

2.00E-OI 2.79E-04 2.08E-04 

3.00E-Ol 4.76E-04 1.04E-03 

4.00E-Ol 7.19E-04 3.02E-03 

S.OOE-Ol 9.97E-04 6.S2E-03 

6.00E-Ol 1.30E-03 1.18E-02 

7.00E-Ol 1.6lE-03 1.89E-02 

8.00E-Ol 1.92E-03 2.78E-02 

9.00E-OI 2.23E-03 3.83E-02 

1.OOE+OO 2.S3E-03 2.S3E-03 S.03E-02 S.03E-02 

2.00E+OO 2.22E-03 4.7SE-03 1.S3E-Ol 2.04E-Ol 

3.00E+OO 1.30E-03 6.0SE-03 1.24E-Ol 3.27E-Ol 

4.00E+OO 9.71E-04 7.03E-03 6.9SE-02 3.97E-OI 

S.OOE+OO 8.36E-04 7.86E-03 3.44E-02 4.3lE-Ol 

6.00E+OO 7.S6E-04 8.62E-03 1.63E-02 4.48E-Ol 

7.00E+OO 6.96E-04 9.3IE-03 7.67E-03 4.SSE-Ol 

8.00E+OO 6.4SE-04 9.96E-03 3.66E-03 4.S9E-OI 

9.00E+OO 6.0lE-04 I.06E-02 1.80E-03 4.6lE-Ol 

1.OOE+Ol S.6lE-04 l.l1E-02 9.3lE-04 4.62E-Ol 

2.00E+OI 3.03E-04 l.SlE-02 1.29E-04 4.64E-Ol 

3.00E+OI 1.8SE-04 1.74E-02 1.26E-04 4.6SE-Ol 

4.00E+Ol 1.28E-04 1.89E-02 1.2SE-04 4.66E-Ol 

S.OOE+Ol 9.70E-OS 2.00E-02 1.23E-04 4.68E-Ol 

7.00E+OI 6.66E-OS 2.l6E-02 1.20E-04 4.70E-Ol 

8.00E+Ol S.79E-OS 2.22E-02 1.18E-04 4.71E-Ol 

9.00E+Ol S.13E-OS 2.28E-02 1.16E-04 4.72E-Ol 

1.OOE+02 4.6lE-OS 2.33E-02 1.lSE-04 4.73E-Ol 

2.00E+02 2.6lE-OS 2.66E-02 9.98E-OS 4.84E-Ol 

3.00E+02 2.3lE-OS 2.90E-02 8.69E-OS 4.93E-Ol 

4.00E+02 2.22E-OS 3.l2E-02 7.S6E-OS S.02E-Ol 

S.OOE+02 2.l7E-OS 3.34E-02 6.S9E-OS S.09E-Ol 

7.00E+02 2.04E-OS 3.76E-02 4.99E-OS S.20E-Ol 

8.00E+02 1.98E-OS 3.96E-02 4.34E-OS S.2SE-Ol 

9.00E+02 1.9lE-OS 4.l6E-02 3.78E-OS S.29E-Ol 

1.OOE+03 1.84E-OS 4.3SE-02 3.29E-OS S.32E-Ol 

2.00E+03 1.17E-OS S.84E-02 8.23E-06 S.SOE-Ol 

3.00E+03 6.88E-06 6.7SE-02 2.06E-06 S.SSE-Ol 

4.00E+03 3.90E-06 7.28E-02 S.14E-07 S.S6E-Ol 

S.OOE+03 2.l6E-06 7.S7E-02 1.29E-07 S.S6E-Ol 

7.00E+03 6.4SE-07 7.82E-02 O.OOE+OO S.S6E-Ol 

8.00E+03 3.48E-07 7.87E-02 O.OOE+OO S.S6E-Ol 

9.00E+03 1.87E-07 7.90E-02 O.OOE+OO S.56E-Ol 

1.OOE+04 9.97E-08 7.9lE-02 O.OOE+OO S.56E-Ol 

B-404 
CLASS Y ·AHAD = 1 MICR.ON STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

LOOE-OI 3.69E-03 3.04E-OI 2.S8E-OI 7.30E-02 6.39E-OI 

2.00E-OI 3.6IE-03 2.8SE-OI 2.17E-OI 1.33E-OI 6.38E-OI 

3.00E-OI 3.63E-03 2.70E-OI 1.82E-OI 1.8IE-OI 6.37E-OI 

4.00E-OI 3.68E-03 2.S7E-OI I.S3E-OI 2.2IE-OI 6.3SE-OI 

S.OOE-OI 3.7SE-03 2.47E-OI 1.29E-OI 2.S2E-OI 6.3IE-OI 

6.00E-OI 3.8IE-03 2.38E-OI I.08E-OI 2.7SE-OI 6.26E-OI 

7.00E-OI 3.87E-03 2.3IE-OI 9.12E-02 2.92E-OI 6.18E-OI 

8.00E-OI 3.9IE-03 2.24E-OI 7.67E-02 3.04E-Ol 6.09E-OI 

9.00E-OI 3.94E-03 2.19E-OI 6.45E-02 3.1IE-OI S.98E-OI 

I.OOE+OO 3.97E-03 2.13E-OI S.42E-02 3.14E-OI S.86E-OI 

2.00E+OO 4.0IE-03 1.80E-OI 9.S9E-03 2.3IE-OI 4.2SE-OI 

3.00E+OO 3.90E-03 1.65E-OI 1.70E-03 1.24E-OI 2.9SE-OI 

4.00E+OO 3. 77E-03 I.S7E-OI 3.00E-04 6.04E-02 2.2IE-OI 

S.OOE+OO 3.62E-03 I.S3E-OI 5.30E-05 2.84E-02 1.85E-OI 

6.00E+OO 3.48E-03 I.SIE-OI 9.37E-06 1.34E-02 1.67E-OI 

7.00E+00 3.34E-03 1.49E-OI 1.66E-06 6.40E-03 I.S9E-OI 

8.00E+OO 3.20E-03 1.49E-OI 2.93E-07 3.16E-03 I.SSE-OI 

9.00E+OO 3.07E-03 1.48E-OI 5.17E-08 1.64E-03 I.S3E-OI 

I.OOE+OI 2.94E-03 1.48E-OI O.OOE+OO 9.16E-04 I.S2E-OI 

2.00E+OI 1.96E-03 1.46E-OI O.OOE+OO 2.3SE-04 1.49E-OI 

3.00E+OI 1.34E-03 1.4SE-OI O.OOE+OO 2.3IE-04 1.47E-OI 

4.00E+OI 9.44E-04 1.43E-OI O.OOE+OO 2.28E-04 1.4SE-OI 

S.OOE+OI 6.98E-04 1.42E-OI O.OOE+OO 2.2SE-04 1.43E-OI 

6.00E+OI 5.43E-04 1.4IE-OI O.OOE+OO 2.22E-04 1.4IE-0l 

7.00E+OI 4.46E-04 1.39E-OI O.OOE+OO 2.19E-04 1.40E-OI 

8.00E+OI 3.8SE-04 1.38E-OI O.OOE+OO 2.16E-04 1.38E-OI 

9.00E+OI 3.47E-04 1.36E-OI O.OOE+OO 2.13E-04 1.37E-OI 

I.OOE+02 3.23E-04 1.3SE-OI O.OOE+OO 2.10E-04 1.3SE-OI 

2.00E+02 2.87E-04 1.22E-OI O.OOE+OO 1.83E-04 1.22E-OI 

3.00E+02 2.89E-04 1.IOE-OI O.OOE+OO I.S9E-04 l.llE-OI 

4.00E+02 2.88E-04 9.98E-02 O.OOE+OO 1.38E-04 I.OOE-OI 

S.OOE+02 2.85E-04 9.06E-02 O.OOE+OO 1.2IE-04 9.10E-02 

6.00E+02 2.80E-04 8.23E-02 O.OOE+OO I.OSE-04 8.27E-02 

7.00E+02 2.74E-04 7.49E-02 O.OOE+OO 9.14E-05 7.S3E-02 

8.00E+02 2.66E-04 6.83E-02 O.OOE+OO 7.95E-05 6.86E-02 

9.00E+02 2. 58E-04 6.23E-02 O.OOE+OO 6.92E-OS 6.27E-02 

I.OOE+03 2.48E-04 S.70E-02 O.OOE+OO 6.03E-OS S.73E-02 

2.00E+03 I.S2E-04 2.SSE-02 O.OOE+OO I.SIE-OS 2.S6E-02 

3.00E+03 8.32E-OS 1.34E-02 O.OOE+OO 3.77E-06 1.3SE-02 

4.00E+03 4.34E-OS 8.2SE-03 O.OOE+OO 9.42E-07 8.29E-03 

S.OOE+OJ 2.21E-OS S.92E-03 O.OOE+OO 2.3SE-07 S.94E-03 

6.00E+03 1.12E-OS 4.8IE-03 O.OOE+OO 5.89E-08 4.82E-03 

7.00E+03 5.62E-06 4.27E-03 O.OOE+OO 1.47E-08 4.27E-03 

8.00E+03 2.8IE-06 4.00E-03 O.OOE+OO O.OOE+OO 4.00E-03 

9.00E+03 1.4IE-06 3.87E-03 O.OOE+OO O.OOE+OO 3.87E-03 

I.OOE+04 7.0SE-07 3.80E-03 O.OOE+OO O.OOE+OO 3.80E-03 

B-40S 
CLASS Y AHAD = 1 MICRON STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------

-------------------------

SYSTEMIC NON-SYSTEMlC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 58E-04 1.04E-05 

2.00E-Ol 5.04E-04 2.10E-04 

3.00E-01 7.08E-04 1.06E-03 

4.00E-Ol 8.83E-04 3.07E-03 

5.00E-Ol 1.04E-03 6.65E-03 

6.00E-Ol 1.17E-03 1.21E-02 

7.00E-Ol 1.29E-03 1.94E-02 

8.00E-Ol 1.40E-03 2.86E-02 

9.00E-Ol 1.50E-03 3.95E-02 

1.00E+00 1.58E-03 1.58E-03 5.19E-02 5.19E-02 

2.00E+00 5.21E-04 2.lOE-03 1.60E-Ol 2.12E-Ol 

3.00E+00 2.71E-04 2. 38E-03 1.30E-Ol 3.42E-Ol 

4.00E+00 2.09E-04 2.58E-03 7.32E-02 4.15E-Ol 

5.00E+00 1.86E-04 2.77E-03 3.62E-02 4.52E-Ol 

6.00E+00 1.74E-04 2.94E-03 1.72E-02 4.69E-Ol 

7.00E+00 1.65E-04 3. l1E-03 8.08E-03 4.77E-Ol 

8.00E+00 1.58E-04 3.27E-03 3.86E-03 4.81E-Ol 

9.00E+00 1.51E-04 3.42E-03 1.90E-03 4.83E-Ol 

1.00E+Ol 1.45E-04 3.56E-03 9.80E-04 4.84E-Ol 

2.00E+Ol 9.76E-05 4.73E-03 1.35E-04 4.86E-Ol 

3.00E+Ol 6.82E-05 5.53E-03 1. 32E-04 4.87E-Ol 

4.00E+Ol 4.97E-05 6. l1E-03 1.31E-04 4.88E-Ol 

5.00E+Ol 3.81E-05 6.54E-03 1.29E-04 4.90E-Ol 

7.00E+Ol 2.62E-05 7.16E-03 1.25E-04 4.'92E-Ol 

8.00E+Ol 2.33E-05 7.40E-03 1.23E-04 4.93E-Ol 

9.00E+Ol 2.16E-05 7. 62E...,03 1.22E-04 4.95E-Ol 

1.00E+02 2.04E-05 7.83E-03 1.20E-04 4.96E-Ol 

2.00E+02 1.88E-05 9.74E-03 1.05E-04 5.07E-Ol 

3.00E+02 1.90E-05 1.16E-02 9.lOE-05 5.17E-Ol 

4.00E+02 1.89E-05 1.35E-02 7.92E-05 5.25E-Ol 

5.00E+02 1.87E-05 1.54E-02 6.90E-05 5.33E-Ol 

7.00E+02 1.79E-05 1.91E-02 5.23E-05 5.45E-Ol 

8.00E+02 1.74E-05 2.08E-02 4.55E-05 5.50E-Ol 

9.00E+02 1.68E-05 2.26E-02 3.96E-05 5.54E-Ol 

1.00E+03 1.62E-05 2.42E-02 3.45E-05 5. 58E-Ol 

2.00E+03 9.95E-06 3.72E-02 8.62E-06 5.76E-Ol 

3.00E+03 5.44E-06 4.48E-02 2.16E-06 5.8lE-01 

4.00E+03 2.83E-06 4.88E-02 5.39E-07 5.82E-Ol 

5.00E+03 1.44E-06 5.08E-02 1.35E-07 5.82E-Ol 

7.00E+03 3.67E-07 5.24E-02 O.OOE+OO 5.82E-Ol 

8.00E+03 1.84E-07 5.27E-02 O.OOE+OO 5.82E-Ol 

9.00E+03 9.20E-08 5.28E-02 O.OOE+OO 5.82E-Ol 

1.00E+04 4.60E-08 5.29E-02 O.OOE+OO 5.82E-Ol 

B-406 
CLASS Y AHAD== 1 MICRON STABLE SILVER 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 4. 38E-03 3.04E-01 2. 58E-01 7.26E-02 6. 39E-Ol 

2.00E-01 6.04E-03 2. 85E-01 2. 17E-Ol 1.31E-01 6. 39E-01 

3.00E-01 8.27E-03 2.70E-01 1. 82E-01 1.77E-01 6. 38E-01 

4.00E-01 1.06E-02 2. 57E-01 1. 53E-Ol 2. 15E-01 6. 36E-01 

5.00E-01 1.27E-02 2.47E-01 1. 29E-01 2.44E-Ol 6.32E-Ol 

6.00E-Ol 1.47E-02 2. 38E-Ol 1.08E-Ol 2. 66E-Ol 6. 27E-01 

7.00E-01 1. 63E-02 2.31E-Ol 9. 12E-02 2.82E-Ol 6.20E-Ol 

8.00E-01 1. 78E-02 2. 24E-01 7. 67E-02 2. 92E-Ol 6. llE-Ol 

9.00E-01 1.90E-02 2. 19E-Ol 6.45E-02 2.98E-Ol 6.00E-01 

1.00E+00 2.00E-02 2. 13E-Ol 5. 42E-02 3.01E-Ol 5. 88E-Ol 

2.00E+00 2.47E-02 1.80E-01 9. 59E-03 2.20E-Ol 4.35E-Ol 

3.00E+00 2. 55E-02 1. 65E-Ol 1.70E-03 1.18E-Ol 3.10E-01 

4.00E+00 2. 54E-02 1.57E-01 3.00E-04 5.73E-02 2.40E-Ol 

5.00E+00 2. 51E-02 1. 53E-Ol 5.30E-05 2.70E-02 2.05E-Ol 

6.00E+00 2. 47E-02 1. 51E-01 9.37E-06 1.27E-02 1.88E-Ol 

7.00E+00 2. 42E-02 1. 49E-Ol 1. 66E-06 6.08E-03 1.80E-Ol 

8.00E+00 2.38E-02 1.49E-Ol 2. 93E-07 3.00E-03 1.76E-Ol 

9.00E+00 2. 34E-02 1. 48E-Ol 5. 17E-08 1. 56E-03 1. 73E-01 

1.00E+Ol 2.30E-02 1.48E-Ol O.OOE+OO 8.71E-04 1.72E-Ol 

2.00E+Ol 1. 99E-02 1.46E-01 O.OOE+OO 2. 25E-04 1.67E-Ol 

3.00E+Ol 1.75E-02 1.45E-Ol O.OOE+OO 2.21E-04 1.63E-Ol 

4.00E+Ol 1. 54E-02 1.43E-Ol O.OOE+OO 2. 18E-04 1. 59E-Ol 

5.00E+Ol 1. 36E-02 1.42E-01 O.OOE+OO 2. 15E-04 1~56E-01 

6.00E+01 1.21E-02 1.41E-01 O.OOE+OO 2.12E-04 1. 53E-Ol 

7.00E+01 1.07E-02 1.39E-Ol O.OOE+OO 2.09E-04 1.50E-01 

8.00E+01 9. 53E-03 1. 38E-Ol O.OOE+OO 2.06E-04 1.47E-Ol 

9.00E+01 8.50E-03 1.36E-01 O.OOE+OO 2.03E-04 1.45E-01 

1.00E+02 7.60E-03 1.35E-01 O.OOE+OO 2.01E-04 1.43E-01 

2.00E+02 3.07E-03 1.22E-01 O.OOE+OO 1. 75E-04 1. 25E-Ol 

3.00E+02 1.91E-03 1.lOE-01 O.OOE+OO 1. 52E-04 1. 12E-01 

4.00E+02 1. 59E-03 9. 98E-02 O.OOE+OO 1.32E-04 1.02E-Ol 

5.00E+02 1. 48E-03 9.06E-02 O.OOE+OO 1. 15E-04 9. 22E-02 

6.00E+02 1.41E-03 8. 23E-02 O.OOE+OO 1.00E-04 8. 38E-02 

7.00E+02 1.36E-03 7.49E-02 O.OOE+OO 8.73E-05 7.63E-02 

8.00E+02 1.31E-03 6. 83E-02 O.OOE+OO 7.60E-05 6.97E-02 

9.00E+02 1.25E-03 6. 23E-02 O.OOE+OO 6. 62E-05 6. 37E-02 

1.00E+03 1.20E-03 5.70E-02 O.OOE+OO 5. 76E-05 5. 83E-02 

2.00E+03 7.01E-04 2. 55E-02 O.OOE+OO 1. 44E-05 2. 62E-02 

3.00E+03 3. 76E-04 1. 34E-02 O.OOE+OO 3.60E-06 1. 38E-02 

4.00E+03 1.94E-04 8. 25E-03 O.OOE+OO 9.00E-07 8. 44E-03 

5.00E+03 9.87E-05 5.92E-03 O.OOE+OO 2.25E-07 6.02E-03 

6.00E+03 4. 98E-05 4. 81E-03 O.OOE+OO 5. 63E-08 4.86E-03 

7.00E+03 2.50E-05 4.27E-03 O.OOE+OO 1.41E-08 4. 29E-03 

8.00E+03 1.25E-05 4.00E-03 O.OOE+OO O.OOE+OO 4.01E-03 

9.00E+03 6.26£-06 3. 87E-03 O.OOE+OO O.OOE+OO 3. 88E-03 

1.00E+04 3. 13E-06 3.80E-03 O.OOE+OO O.OOE+OO 3.81E-03 

B-407 
CLASS Y AMAD= 1 MICRON STABLE SILVER 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -------------------------------------------------

SYSTEMIC NON-SYSTEl1IC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 12E-05 1.04E-05 

2.00E-01 2. 76E-05 2.08E-04 

3.00E-Ol 5.02E-05 1.04E-03 

4.00E-01 8.00E-05 3.02E-03 

5.00E-Ol 1. 17E-04 6. 52E-03 

6.00E-Ol 1.60E-04 1. 18E-02 

7.00E-01 2.08E-04 1.89E-02 

8.00E-Ol 2. 61E-04 2. 78E-02 

9.00E-01 3.18E-04 3. 83E-02 

1.00E+00 3.77E-04 3.77E-04 5.03E-02 5.03E-02 

2.00E+00 6.77E-04 1.05E-03 1.53E-01 2.04E-Ol 

3.00E+00 6. 92E-04 1. 75E-03 1.24E-01 3.27E-Ol 

4.00E+00 6.50E-04 2.40E-03 6.95E-02 3.97E-Ol 

5.00E+00 6.00E-04 3.00E-03 3. 44E-02 4.31E-Ol 

6.00E+00 5. 53E-04 3.55E-03 1.63E-02 4.48E-01 

7.00E+00 5. 12E-04 4.06E-03 7.67E-03 4. 55E-Ol 

8.00E+00 4.76E-04 4. 54E-03 3. 66E-03 4. 59E-01 

9.00E+00 4.45E-04 4. 98E-03 1.80E-03 4. 61E-01 

1.00E+Ol 4. 19E-04 5.40E-03 9.31E-04 4.62E-Ol 

2.00E+Ol 2. 93E-04 8.76E-03 1. 29E-04 4.64E-Ol 

3.00E+Ol 2.48E-04 1. 14E-02 1.26E-04 4.65E-Ol 

4.00E+Ol 2. 18E-04 1.37E-02 1.25E-04 4. 66E-Ol 

5.00E+Ol 1.92E-04 1.58E-02 1.23E-04 4.68E-Ol 

6.00E+Ol 1.71E-04 1.76E-02 1.21E-04 4. 69E-Ol 

7.00E+Ol 1. 52E-04 1.92E-02 1.20E-04 4.70E-Ol 

8.00E+Ol 1. 35E-04 2.06E-02 1. 18E-04 4. 71E-Ol 

9.00E+Ol 1.21E-04 2.19E-02 1. 16E-04 4.72E-Ol 

1.00E+02 1.08E-04 2.30E-02 1. 15E-04 4.73E-Ol 

2.00E+02 4.48E-05 2. 99E-02 9. 98E-05 4. 84E-Ol 

3.00E+02 2.86E-05 3. 34E-02 8.69E-05 4. 93E-Ol 

4.00E+02 2.42E-05 3.60E-02 7. 56E-05 5.02E-01 

5.00E+02 2.25E-05 3.83E-02 6. 59E-05 5.09E-Ol 

7.00E+02 2.07E-05 4. 26E-02 4. 99E-05 5.20E-Ol 

8.00E+02 1. 99E-05 4.47E-02 4.34E-05 5.25E-Ol , . ~" 9.00E+02 1.91E-05 4.66E-02 3. 78E-05 5.29E-Ol 

1.00E+03 1.83E-05 4. 85E-02 3. 29E-05 5. 32E-Ol 

2.00E+03 1.07E-05 6.28E-02 8. 23E-06 5.50E-Ol 

3.00E+03 5.72E-06 7.07E-02 2.06E-06 5.55E-Ol 

4.00E+03 2.96E-06 7.49E-02 5. 14E-07 5.56E-Ol 

5.00E+03 1.50E-06 7.71E-02 1.29E-07 5. 56E-01 

7.00E+03 3.80E-07 7.87E-02 O.OOE+OO 5.56E-Ol 

8.00E+03 1.91E-07 7.90E-02 O.OOE+OO 5. 56E-01 

9.00E+03 9. 54E-08 7.91E-02 O.OOE+OO 5. 56E-Ol 

1.00E+04 4.77E-08 7.92E-02 O.OOE+OO 5. 56E-01 

B-408 
CLASS Y AMAD = 1 MICRON STABLE CADMIUM 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 4. 39E-03 3.04E-Ol 2.SBE-OI 7.26E-02 6.39E-OI 

2.00E-OI 6.07E-03 2. BSE-OI 2.l7E-01 1.3IE-01 6. 39E-OI 

3.00E-Ol B.32E-03 2.70E-OI 1. B2E-Ol 1.77E-01 6.3BE-Ol 

4.00E-Ol 1.07E-02 2.S7E':'01 1.S3E-OI 2. ISE-OI 6. 36E-OI 

5.00E-OI I.2BE-02 2.47E-OI I.29E-Ol 2.44E-OI 6.33E-OI 

6.00E-OI I.4BE-02 2.3BE-OI 1.0BE-01 2. 66E-OI 6.27E-Ol 

7.00E-OI I.6SE-02 2.3IE-01 9.l2E-02 2.B2E-OI 6.20E-0l 

B.00E-01 1.BOE-02 2.24E-OI 7. 67E-02 2. 92E-OI 6.lIE-OI 

9.00E-Ol I. 93E-02 2.19E-Ol 6.45E-02 2.9BE-OI 6.0lE-01 

1.00E+00 2.04E-02 2.13E-OI 5. 42E-02 3.0IE-OI 5.B9E-01 

2.00E+00 2.S7E-02 1. BOE-Ol 9.59E-03 2.20E-Ol 4. 36E-01 

3.00E+00 2. 72E-02 1. 65E-OI I.70E-03 1.lBE-0l 3. 12E-01 

4.00E+00 2.7BE-02 I.S7E-01 3.00E-04 S.73E-02 2.42E-01 

5.00E+00 2.BIE-02 I.S3E-OI S.30E-05 2.70E-02 2.0BE-01 

6.00E+00 2.B2E-02 I.5IE-Ol 9.37E-06 1.27E-02 I.91E-Ol 

7.00E+00 2.B3E-02 1. 49E-01 1. 66E-06 6.08E-03 1.B4E-OI 

B.OOE+OO 2.83E-02 1.49E-OI 2.93E-07 3.00E-03 1. BOE-OI 

9.00E+00 2.B4E-02 1. 48E-OI 5.17E-OB 1. 56E-03 1.7BE-OI 

l.OOE+OI 2. 84E-02 I.48E-0l O.OOE+OO 8.71E-04 1.77E-OI 

2.00E+Ol 2.B6E-02 I.46E-OI O.OOE+OO 2.2SE-04 I.7SE-OI 

3.00E+OI 2.8BE-02 1.4SE-OI O.OOE+OO 2.21E-04 1. 74E-Ol 

4.00E+OI 2.9IE-02 1. 43E-Ol O.OOE+OO 2.IBE-04 1. 73E-OI 

5.00E+OI 2.93E-02 I.42E-0l ·O.OOE+OO 2.15E-04 I.71E-Ol 

6.00E+Ol 2. 95E-02 1.41E-Ol O.OOE+OO 2. 12E-04 1.70E-OI 

7.00E+OI 2.97E-02 l.39E-01 O.OOE+OO 2.09E-04 I.69E-0l 

8.00E+OI 2. 99E-02 1.3BE-01 O.OOE+OO 2.06E-04 1. 68E-Ol 

9.00E+0l 3.02E-02 1. 36E-Ol O.OOE+OO 2.03E-04 I.67E-01 

I.00E+02 3.04E-02 1.3SE-01 O.OOE+OO 2.0lE-04 I.65E-OI 

2.00E+02 3.25E-02 1. 22E-01 O.OOE+OO I.7SE-04 I. 54E-01 

3.00E+02 3.46E-02 I.lOE-OI O.OOE+OO 1. 52E-04 1.4SE-Ol 

4.00E+02 3. 66E-02 9.9BE-02 O.OOE+OO 1.32E-04 I.37E-OI 

5.00E+02 3. BSE-02 9.06E-02 O.OOE+OO I.I5E-04 1. 29E-OI 

6.00E+02 4.04E-02 B.23E-02 O.OOE+OO 1.00E-04 1. 23E-01 

7.00E+02 4.2IE-02 7.49E-02 O.OOE+OO B.73E-OS 1.17E-01 

B.00E+02 4. 38E-02 6.B3E-02 O.OOE+OO 7.60E-05 I.I2E-01 

9.00E+02 4.S3E-02 6. 23E-02 O.OOE+OO 6. 62E-OS 1.OBE-01 

I.00E+03 4.6BE-02 5.70E-02 O.OOE+OO 5. 76E-05 1.04E-01 

2.00E+03 5.66E-02 2. 55E-02 O.OOE+OO 1. 44E-OS B.2IE-02 

3.00E+03 5.9BE-02 I.34E-02 O.OOE+OO 3.60E-06 7.32E-02 

4.00E+03 5. 93E-02 B.25E-03 O.OOE+OO 9.00E-07 6.7SE-02 

5.00E+03 5. 69E-02 5.92E-03 O.OOE+OO 2.2SE-07 6.2BE-02 

7.00E+03 5.03E-02 4. 27E-03 O.OOE+OO 1.4lE-OB S.46E-02 

B.00E+03 4. 69E-02 4.00E-03 O.OOE+OO O.OOE+OO S.09E-02 

9.00E+03 4.36E-02 3.B7E-03 O.OOE+OO O.OOE+OO 4. 74E-02 

I.OOE+04 4.04E-02 3. BOE-03 O.OOE+OO O.OOE+OO 4.43E-02 

2.00E+04 I.90E-02 3. 74E-03 O.OOE+OO O.OOE+OO 2. 27E-02 

B-409 
CLASS Y AMAD = I MICRON STABLE CADMIUM 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUNULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1. OOE-OI 2. 64E-08 I.04E-05 

2.00E-OI 6. 56E-08 2.08E-04 

3.00E-OI 1.20E-07 I.04E-03 

4.00E-Ol 1. 92E-07 3.02E-03 

5.00E-01 2.8IE-07 6.52E-03 

6. OOE-O I 3.87E-07 1. 18E-02 

7.00E-01 5.06E-07 1.89E-02 

8. OOE-O I 6. 37E-07 2. 78E-02 

9.00E-OI 7. 79E-07 3. 83E-02 

1.00E+OO 9.30E-07 9.30E-07 5.03E-02 5.03E-02 

2.00E+OO 1.80E-06 2. 73E-06 1.53E-OI 2.04E-OI 

3.00E+OO 2.02E-06 4. 75E-06 1.24E-OI 3.27E-Ol 

4.00E+OO 2.09E-06 6.84E-06 6.9SE-02 3.97E-Ol 

S.OOE+OO 2.I2E-06 8. 96E-06 3.44E-02 4.3IE-Ol 

6.00E+OO 2.14E-06 I. llE-OS I.63E-02 4.48E-OI 

7.00E+OO 2. ISE-06 I. 32E-OS 7. 67E-03 4.5SE-OI 

8.00E+OO 2.1SE-06 I. 54E-05 3.66E-03 4.59E-OI 

9.00E+OO 2.lSE-06 1.7SE-05 I.80E-03 4.61E-Ol 

1.00E+Ol 2.16E-06 I.97E-05 9.31E-04 4.62E-OI 

2.00E+Ol 2. 17E-06 4.14E-OS 1.29E-04 4. 64E-Ol 

3.00E+OI 2. 19E-06 6. 32E-OS I.26E-04 4.6SE-OI 

4.00E+Ol 2.21E-06 8. 52E-OS 1.25E-04 4.66E-OI 

s.OOE+Ol 2. 22E-06 1. 07E-04 I.23E-04 4.68E-0l 

7.00E+OI 2. 26E-06 1. 52E-04 I.20E-04 4.70E-Ol 

8.00E+Ol 2. 27E-06 I.7sE-04 I.I8E-04 4. 71E-OI 

9.00E+Ol 2. 29E-06 1. 98E-04 I.I6E-04 4.72E-OI 

1.00E+02 2.3IE-06 2.2IE-04 I.I5E-04 4. 73E-OI 

2.00E+02 2.47E-06 4.s9E-04 9. 98E-05 4. 84E-Ol 

3.00E+02 2.63E-06 7.I4E-04 8.69E-05 4. 93E-Ol 

4.00E+02 2. 78E-06 9. 85E-04 7.s6E-Os s.02E-OI 

s.OOE+02 2. 92E-06 I.27E-03 6.59E-05 s.09E-OI 

7.00E+02 3.20E-06 1. 88E-03 4. 99E-Os 5.20E-OI 

8.00E+02 3. 32E-06 2.2IE-03 4. 34E-Os s.2sE-OI 

9.00E+02 3.44E-06 2.ssE-03 3. 78E-Os 5.29E-OI 

I.OOE+03 3. 55E-06 2.90E-03 3.29E-Os 5.32E-OI 

2.00E+03 4.30E-06 6.87E-03 8. 23E-06 5.50E-Ol 

3.00E+03 4. 54E-06 I.I3E-02 2.06E-Ob 5.ssE-OI 

4.00E+03 4.s0E-06 1.59E-02 s.I4E-07 5. 56E-OI 

5.00E+03 4. 32E-06 2.03E-02 I.29E-07 5.56E-OI 

7.00E+03 3. 82E-06 2. 84E-02 O.OOE+OO 5.56E-OI 

8.00E+03 3.5bE-06 3.2IE-02 O.OOE+OO s.56E-OI 

9.00E+03 3.3lE-06 3.5bE-02 O.OOE+OO 5.5bE-OI 

1.00E+04 3.07E-06 3.87E-02 O.OOE+OO 5. 56E-OI 

2.00E+04 I.44E-Ob 6.03E-02 O.OOE+OO 5.5bE-OI 

B-410 
CLASS Y AHAD = 1 MICRON STABLE CERIUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------~---------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.90E-03 3.04E-Ol 2.58E-01 7.31E-02 6. 39E-Ol 

2.00E-Ol 3. 92E-03 2. 85E-Ol 2.17E-Ol 1. 33E-Ol 6.39E-Ol 

3.00E-Ol 3.93E-03 2.70E-01 1.82E-Ol 1.82E-01 6.38E-Ol 

4.00E-Ol 3. 95E-03 2. 57E-Ol 1. 53E-Ol 2.21E-Ol 6.36E-Ol 

5.00E-Ol 3. 96E-03 2.47E-Ol 1.29E-01 2. 52E-Ol 6.32E-01 

6.00E-Ol 3. 97E-03 2. 38E-01 1.08E-Ol 2.76E-Ol 6.27E-Ol 

7.00E-Ol 3. 99E-03 2.31E-Ol 9. 12E-02 2.94E-01 6.20E-Ol 

8.00E-Ol 4.00E-03 . 2. 24E-Ol 7. 67E-02 3.05E-Ol 6.10E-01 

9.00E-01 4.01E-03 2. 19E-01 6.45E-02 3. 12E-01 6.00E-Ol 

1.00E+00 4.01E-03 2. 13E-Ol 5. 42E-02 3. 15E-01 5.87E-01 

2.00E+00 4.06E-03 1.80E-01 9.59E-03 2.32E-Ol 4. 26E-Ol 

3.00E+00 4.09E-03 1. 65E-01 1.70E-03 1. 25E-Ol 2. 95E-01 

4.00E+00 4. 11E-03 1.57E-01 3.00E-04 6.07E-02 2.22E-Ol 

5.00E+00 4. 13E-03 1.53E-01 5.30E-05 2. 86E-02 1. 85E-01 

6.00E+00 4. 14E-03 1.51E-01 9.37E-06 1.34E-02 1. 68E-01 

7.00E+00 4. 16E-03 1. 49E-01 1. 66E-06 6. 44E-03 1.60E-Ol 

8.00E+00 4. 18E-03 1.49E-Ol 2.93E-07 3. 18E-03 1.56E-Ol 

9.00E+00 4. 19E-03 1. 48E-01 5. 17E-08 1. 65E-03 1. 54E-01 

1.00E+01 4.21E-03 1.48E-01 O.OOE+OO 9.20E-04 1. 53E-Ol 

2.00E+Ol 4. 38E-03 1. 46E-Ol O.OOE+OO 2. 36E-04 1.51E-01 

3.00E+Ol 4.54£-03 1.45E-Ol O.OOE+OO 2.32E-04 1.50E-01 

4.00E+01 4.71E-03 1. 43E-Ol O.OOE+OO 2. 29E-04 1. 48E-Ol 

5.00E+Ol 4. 88E-03 1.42E-01 O.OOE+OO 2.26E-04 1.47E-01 

6.00E+Ol 5.04E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1.46E-01 

7.00E+Ol 5. 21E-03 1.39E-01 O.OOE+OO 2.20E-04 1.45E-01 

8.00E+01 5. 38E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1.43E-Ol 

9.00E+01 5. 55E-03 1.36E-01 O.OOE+OO 2. 14E-04 1.42E-Ol 

1.00E+02 5. 72E-03 1.35E-01 O.OOE+OO 2. 11E-04 1.41E-01 

2.00E+02 7.41E-03 1.22E-01 O.OOE+OO 1. 84E-04 1.29E-01 

3.00E+02 9.09E-03 1.lOE-01 O.OOE+OO 1.60E-04 1. 19E-Ol 

4.00E+02 1.07E-02 9. 98E-02 O.OOE+OO 1.39E-04 1. 11E-01 

5.00E+02 1. 24E-02 9.06E-02 O.OOE+OO 1. 21E-04 1.03E-Ol 

6.00E+02 1.39£-02 8. 23E-02 O.OOE+OO 1.05E-04 9. 63E-02 

7.00E+02 1. 54E-02 7.49E-02 O.OOE+OO 9. 18E-05 9.04E-02 

8.00E+02 1.68E-02 6. 83E-02 O.OOE+OO 7.99E-05 8. 52E-02 

9.00E+02 1. 82E-02 6. 23E-02 O.OOE+OO 6. 96E-05 8.06E-02 

1.00E+03 1.94E-02 5.70E-02 O.OOE+OO 6.06E-05 7. 65E-02 

2.00£+03 2. 75E-02 2. 55E-02 O.OOE+OO 1.51E-05 5.30E-02 

3.00E+03 2. 92E-02 1. 34E-02 O.OOE+OO 3.78E-06 4. 26E-02 

4.00E+03 2. 75E-02 8. 25E-03 O.OOE+OO 9. 46E-07 3. 58E-02 

5.00E+03 2. 44E-02 5. 92E-03 O.OOE+OO 2. 37E-07 3.03E-02 

7.00E+03 1.77E-02 4. 27E-03 O.OOE+OO 1. 48E-08 2. 19E-02 

8.00E+03 1. 47E-02 4.00E-03 O.OOE+OO O.OOE+OO 1. 87E-02 

9.00E+03 1. 22E-02 3. 87E-03 O.OOE+OO O.OOE+OO 1. 61E-02 

1.00E+04 1.01E-02 3.80E-03 O.OOE+OO O.OOE+OO 1.39E-02 

2.00E+04 1.40E-03 3. 74E-03 O.OOE+OO O.OOE+OO 5. 14E-03 

B-411 
CLASS Y AHA.D = 1 MICRON STABLE CERIUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1. OOE-OI 6.6IE-08 I.04E-05 

2.00E-OI 1.44E-07 2.lOE-04 

3.00E-OI 2.2IE-07 I.06E-03 

4.00E-Ol 2. 99E-07 3.07E-03 

S.OOE-OI 3.77E-07 6.67E-03 

6.00E-OI 4.S6E-07 1.2IE-02 

7.00E-OI 5.3SE-07 1. 94E-02 

8.00E-OI 6.14E-07 2. 86E-02 

9.00E-OI 6. 93E-07 3.96E-02 

I.OOE+OO 7. 72E-07 7.72E-07 S.2IE-02 S.2IE-02 

2.00E+OO 8.00E-07 I.S7E-06 1.6IE-0l 2. 13E-OI 

3.00E+OO 8.07E-07 2. 38E-06 1.3IE-OI 3.44E-OI 

4.00E+OO 8.12E-07 3.I9E-06 7.36E-02 4.17E-Ol 

S.OOE+OO 8.ISE-07 4.0IE-06 3. 64E-02 4.S4E-OI 

6.00E+OO 8.I9E-07 4. 83E-06 1. 73E-02 4.7IE-Ol 

7.00E+OO 8. 22E-07 S.6SE-06 8.l3E-03 4. 79E-OI 

8.00E+OO 8. 26E-07 6.47E-06 3. BBE-03 4. 83E-OI 

9.00E+OO 8.29E-07 7.30E-06 1.9IE-03 4.8SE-Ol 

I.OOE+OI 8. 32E-07 8.13E-06 9.8SE-04 4. 86E-OI 

2.00E+Ol 8.6SE-07 1.66E-05 1. 36E-04 4. 88E-OI 

3.00E+Ol 8. 98E-07 2. SSE-OS I.33E-04 4.89E-OI 

4.00E+Ol 9.3lE-07 3. 46E-OS 1.31E-04 4.91E-Ol 

5.00E+OI 9.64E-07 4.41E-OS 1.29E-04 4. 92E-Ol 

7.00E+Ol 1.03E-06 6.4lE-OS 1.26E-04 4.9SE-Ol 

8.00E+Ol 1.06E-06 7.46E-05 1.24E-04 4.96E-OI 

9.00E+Ol 1.10E-06 8.S4E-OS 1. 22E-04 4.97E-Ol 

1.00E+02 1.13E-06 9.6SE-OS 1.2IE-04 4.98E-Ol 

2.00E+02 1. 46E-06 2. 26E-04 l.OSE-04 S.IOE-Ol 

3.00E+02 1.80E-06 3.90E-04 9.14E-OS 5. 19E-Ol 

4.00E+02 2. 13E-06 S.86E-04 7. 96E-OS S.28E-Ol 

S.OOE+02 2.4SE-06 8.lSE-04 6. 93E-OS 5.35E-0l 

7.00E+02 3.05E-06 1.37E-03 5. 25E-05 5.47E-Ol 

8.00E+02 3.33E-06 1.68E-03 4.S7E-OS S.S2E-Ol 

9.00E+02 3.S9E-06 2.03E-03 3. 98E-OS S.57E-Ol I 1.OOE+03 3. 84E-06 2.40E-03 3.47E-OS S.60E-Ol 

2.00E+03 S.44E-06 7. 18E-03 8. 66E-06 S.79E-Ol 

3.00E+03 S.79E-06 1. 29E-02 2. 17E-06 S.84E-0l 

4.00E+03 5.4SE-06 1.8SE-02 S.4lE-07 S.8SE-Ol 

S.OOE+03 4.83E-06 2.37E-02 1.3SE-07 S.8SE-Ol 

7.00E+03 3.S0E-06 3.20E-02 O.OOE+OO S.8SE-Ol 

8.00E+03 2.91E-06 3.S2E-02 O.OOE+OO S.8SE-Ol 

9.00E+03 2.41E-06 3. 78E-02 O.OOE+OO S.8SE-Ol 

1.OOE+04 l.99E-06 4.00E-02 O.OOE+OO S.8SE-Ol 

2.00E+04 2. 78E-07 4. 88E-02 O.OOE+OO 5.8SE-Ol 

B-412 
CLASS Y AHA» = 1 MICRON HALFLIFE= 3.25E+Ol DAYS CERIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3. 89E-03 3.03E-OI 2. S8E-0l 7. 29E-02 6.3SE-OI 

2.00E-OI 3.90E-03 2.S4E-OI 2.I6E-Ol 1. 32E-01 6. 36E-Ol 

3.00E-01 3.91E-03 2.6SE-Ol 1.SlE-Ol 1. SlE-Ol 6.34E-01 

4.00E-Ol 3.91E-03 2.SSE-Ol 1.S2E-Ol 2. 19E-01 6.31E-Ol 

S.OOE-Ol 3. 92E-03 2.4SE-01 1.2SE-Ol 2.S0E-01 6.26E-01 

6.00E-01 3. 92E-03 2.3SE-01 1.07E-Ol 2. 73E-01 6.19E-01 

7.00E-01 3. 93E-03 2.27E-Ol S.99E-02 2.S9E-Ol 6.11E-OI 

S.OOE-01 3. 93E-03 2.21E-Ol 7.S4E-02 3.00E-01 6.00E-Ol 

9.00E-01 3.93E-03 2. 14E-Ol 6. 33E-02 3.07E-01 S.SSE-01 

1.00E+OO 3. 93E-03 2.09E-Ol S.31E-02 3.09E-01 S.7SE-Ol 

2.00E+OO 3.S9E-03 1. 73E-Ol 9.19E-03 2.23E-Ol 4.09E-Ol 

3.00E+OO 3. 84E-03 1.S4E-Ol 1.S9E-03 I.17E-Ol 2. 77E-01 

4.00E+OO 3.17E-03 1.44E-Ol 2.7SE-04 S. S7E-02 2.04E-01 

S.OOE+OO 3.71E-03 1.37E-Ol 4. 76E-OS 2.S7E-02 1. 67E-Ol 

6.00E+OO 3.6SE-03 1.32E-01 S.24E-06 1. 18E-02 1.48E-Ol 

7.00E+OO 3.SSE-03 1.29E-01 1. 43E-06 S.S4E-03 1.38E-01 

S.OOE+OO 3. S2E-03 1.2SE-01 2.47E-07 2. 68E-03 1.32E-Ol 

9.00E+OO 3.46E-03 1. 22E-Ol 4. 27E-OS 1. 36E-03 I.27E-Ol 

1.00E+Ol 3.40E-03 1.20E-Ol O.OOE+OO 7.44E-04 1.24E-01 

2.00E+01 2.S6E-03 9.S6E-02 O.OOE+OO 1.S4E-04 9.S6E-02 

3. OO~+Ol 2.40E-03 7. 64E-02 O.OOE+OO 1.23E-04 7.90E-02 

4.00E+OI 2.01E-03 6. llE-02 O.OOE+OO 9. 76E-OS 6. 32E-02 

S.OOE+Ol 1.6SE-03 4.S9E-02 O.OOE+OO 7.7SE-OS S.06E-02 

6.00E+01 1.40E-03 3.91E-02 O.OOE+OO 6.20E-OS 4.0SE-02 

7.00E+01 1. 17E-03 3. 13E-02 O.OOE+OO 4. 94E-OS 3.2SE-02 

S.OOE+Ol 9.77E-04 2.50E-02 O.OOE+OO 3. 94E-OS 2.60E-02 

9.00E+01 S.14E-04 2.00E-02 O.OOE+OO 3. 14E-05 2.0SE-02 

1.OOE+02 6. 17E-04 1.60E-02 O.OOE+OO 2.S0E-05 1. 67E-02 

2.00E+02 1.04E-04 1.71E-03 O.OOE+OO 2.5SE-06 1.82E-03 

3.00E+02 I.51E-05 1.S3E-04 O.OOE+OO 2. 66E-07 1. 99E-04 

4.00E+02 2. 12E-06 1.97E-05 O.OOE+OO 2. 74E-OS 2.1SE-05 

5.00E+02 2.S9E-07 2.12E-06 O.OOE+OO O.OOE+OO 2.41E-06 

6.00E+02 3.S6E-OS 2.2SE-07 O.OOE+OO O.OOE+OO 2. 67E-07 

· ' ".: 

", '. ~ 

B-4l3 
CLASS Y AHA.D == 1 MICRON HALFLIFE== 3.25E+Ol DAYS CERIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOL ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-0l 6.60E-08 1.04E-05 

2.00E-Ol 1.43E-07 2.09E-04 

3.00E-Ol 2.20E-07 1.05E-03 

4.00E-Ol 2. 97E-07 3.05E-03 

5.00E-Ol 3. 73E-07 6.60E-03 

6.00E-Ol 4.50E-07 1.19E-02 

7.00E-Ol 5.27E-07 1.91E-02 

8.00E-Ol 6.03E-07 2.81E-02 

9.00E-Ol 6.80E-07 3. 88E-02 

1.00E+OO 7. 56E-07 7. 56E-07 5.10E-02 5.lOE-02 

2.00E+OO 7.67E-07 1. 51E-06 I.54E-Ol 2.04E-Ol 

3.00E+OO 7. 57E-07 2. 23E-06 1. 23E-Ol 3. 22E-Ol 

4.00E+OO 7. 45E-07 2. 93E-06 6.76E-02 3.83E-Ol 

5.00E+OO 7. 33E-07 3.60E-06 3. 27E-02 4.08E-Ol 

6.00E+OO 7.20E-07 4. 25E-06 1.52E-02 4.l4E-OI 

7.00E+OO 7.08E-07 4. 86E-06 7.00E-03 4.13E-Ol 

8.00E+OO 6.96E-07 5. 46E-06 3.27E-03 4.07E-Ol 

9.00E+OO 6. 84E-07 6.03E-06 1. 58E-03 4.00E-Ol 

1.00E+Ol 6.72E-07 6. 57E-06 7. 96E-04 3. 93E-Ol 

2.00E+Ol 5. 65E-07 1.09E-05 8. 85E-05 3. 19E-Ol 

3.00E+Ol 4.74E-07 1.34E-05 7.01E-05 2. 58E-Ol 

4.00E+Ol 3.97E-07 1. 48E-05 5. 59E-05 2.09E-Ol 

5.00E+Ol 3. 32E-07 1. 52E-05 4.45E-05 1.69E-Ol 

6.00E+Ol 2.77E-07 1.50E-05 3. 55E-05 1.37E-Ol 

7.00E+Ol 2. 32E-07 1.44E-05 2. 83E-05 1. BE-Ol 

8.00E+Ol 1. 93E-07 1. 35E-05 2. 25E-05 9.00E-02 

9.00E+Ol 1.61E-07 1. 25E-05 1.79E-05 7. 29E-02 

1.OOE+02 1.34E-07 1. 14E-05 1. 43E-05 5.90E-02 

2.00E+02 2.06E-08 3. 18E-06 1.48E-06 7.16E-03 

B-414 
ClASS Y AKAD == 1 MICRON BALFLIFE= 2.84E+02 DAYS CERIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.90E-03 3.04E-Ol 2.5BE-Ol 7.30E-02 6. 39E-Ol 

2.00E-Ol 3.9lE-03 2.B5E-Ol 2.l7E-Ol 1.33E-Ol 6.39E-Ol 

3.00E-Ol 3.93E-03 2.70E-Ol 1. B2E-Ol 1. S2E-Ol 6.3BE-Ol 

4.00E-Ol 3. 94E-03 2. 57E-Ol 1. 53E-Ol 2.2lE-Ol 6. 35E-Ol 

5.00E-Ol 3. 96E-03 2.47E-Ol 1. 29E-Ol 2. 52E-Ol 6. 32E-Ol 

6.00E-Ol 3.97E-03 2.3BE-Ol 1.OSE-Ol 2. 76E-Ol 6.26E-Ol 

7.00E-Ol 3.9SE-03 2.3lE-Ol 9.l1E-02 2.93E-Ol 6.l9E-Ol 

S.OOE-Ol 3. 99E-03 2. 24E-Ol 7. 66E-02 3.05E-Ol 6.09E-Ol 

9.00E-Ol 4.00E-03 2.lBE-Ol 6. 44E-02 3.l2E-0l 5.9BE-Ol 

1.OOE+OO 4.00E-03 2.l3E-Ol 5.4lE-02 3.l5E-Ol 5.B6E-Ol 

2.00E+OO 4.04E-03 1. BOE-Ol 9. 54E-03 2.3lE-0l 4.24E-Ol 

3.00E+OO 4.06E-03 1. 63E-Ol 1.6SE-03 1. 24E-Ol 2. 93E-Ol 

4.00E+OO 4.07E-03 1.55E-0l 2.97E-04 6.0lE-02 2.20E-0l 

5.00E+OO 4.08E-03 1.SlE-0l 5. 23E-OS 2.S2E-02 1. 83E-Ol 

6.00E+OO 4.0SE-03 1.4BE-Ol 9. 23E-06 1.33E-02 1.66E-0l 

7.00E+OO 4.09E-03 1. 47E-Ol 1. 63E-06 6. 33E-03 1. 57E-Ol 

8.00E+OO 4.lOE-03 1.46E-Ol 2.87E-07 3.l2E-03 1. 53E-Ol 

9.00E+OO 4.l0E-03 1.45E-Ol S.06E-OS 1.6lE-03 1.SlE-Ol 

1.OOE+Ol 4.l1E-03 1.4SE-OI O.OOE+OO 8.9SE-04 1.50E-OI 

2.00E+Ol 4.I7E-03 1. 39E-Ol O.OOE+OO 2. 25E-04 1. 44E-Ol 

3.00E+Ol 4. 22E-03 1.35E-Ol O.OOE+OO 2.l6E-04 -1.39E-OI 

4.00E+OI 4. 27E-03 1.30E-OI O.OOE+OO 2.08E-04 1.3SE-OI 

5.00E+Ol 4. 32E-03 1.26E-Ol O.OOE+OO 2.00E-04 I.30E-Ol 

6.00E+Ol 4. 36E-03 I.2IE-OI O.OOE+OO 1. 93E-04 I. 26E-Ol 

7.00E+Ol 4. 39E-03 1.17E-Ol O.OOE+OO 1.8SE-04 1.22E-Ol 

8.00E+Ol 4.43E-03 1.l3E-Ol O.OOE+OO 1. 78E-04 1.lSE-Ol 

9.00E+Ol 4.45E-03 1.09E-0l O.OOE+OO 1.72E-04 1.14E-0l 

1.OOE+02 4. 48E-03 1.06E-Ol O.OOE+OO 1. 65E-04 1.lOE-0l 

2.00E+02 4. 55E-03 7.4SE-02 . O.OOE+OO 1.13E-04 7.95E-02 

3.00E+02 4.37E-03 5.30E-02 O.OOE+OO 7.69E-05 5. 75E-02 

4.00E+02 4.05E-03 3. 76E-02 O.OOE+OO 5. 25E-05 4.17E-02 

5.00E+02 3. 65E-03 2.68E-02 O.OOE+OO 3.5SE-05 3.0SE-02 

6.00E+02 3.22E-03 1.9lE-02 O.OOE+OO 2. 44E-05 2.23E-02 

7.00E+02 2.S0E-03 1. 36E-02 O.OOE+OO 1.67E-05 1. 64E-02 

8.00E+02 2. 39E-03 9.71E-03 O.OOE+OO 1.14E-05 1.2lE-02 

9.00E+02 2.02E-03 6. 95E-03 O.OOE+OO 7. 75E-06 S.9SE-03 '., . 

,. 1.OOE+03 1.70E-OJ 4.9SE-03 O.OOE+OO 5.29E-06 6.6BE-03 

2.00E+03 2.l0E-04 1. 94E-04 O.OOE+OO 1.lSE-07 4.04E-04 

3.00E+03 1. 95E-OS B.9lE-06 O.OOE+OO O.OOE+OO 2.84E-05 

4.00E+03 1.60E-06 4.S0E-07 O.OOE+OO O.OOE+OO 2.0BE-06 

S.OOE+03 1. 24E-07 3.00E-OB O.OOE+OO O.OOE+OO 1.54E-07 

B-4l5 
CLASS Y AMAD - 1 MICRON HALFLIFE= 2.84£+02 DAYS CERIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 6.6IE-08 I.04E-05 

2.00E-OI 1. 43E-07 2.10E-04 

3.00E-Ol 2.2IE-07 I.06E-03 

4.00E-OI 2. 99E-07 3.07E-03 

5.00E-OI 3.77E-07 6.66E-03 

6.00E-OI 4.SSE-07 1.2IE-02 

7.00E-0l S.34E-07 1. 94E-02 

8.00E-OI 6.13E-07 2. 86E-02 

9.00E-OI 6. 92E-07 3. 95E-02 

I.OOE+OO 7.7lE-07 7.7lE-07 S.20E-02 5.20E-02 

2.00E+OO 7.97E-07 1. S7E-06 I.60E'-OI 2.12E-OI 

3.00E+OO 8.0IE-07 2. 36E-06 1.30E-OI 3.4IE-OI 

4.00E+OO 8.04E-07 3.16E-06 7.29E-02 4.13E-OI 

S.OOE+OO S.OSE-07 3. 96E-06 3.60E-02 4. 48E-OI 

6.00E+OO 8.07E-07 4. 76E-06 1.70E-02 4.64E-OI 

7.00E+OO 8.0SE-07 S.SSE-06 7. 99E-03 4.7IE-OI 

8.00E+OO S.IOE-07 6.3SE-06 3.8IE-03 4. 74E-OI 

9.00E+OO S.llE-07 7.14E-06 1.87E-03 4. 74E-OI 

I.OOE+OI 8.12E-07 7. 94E-06 9.62E-04 4. 74E-OI 

2.00E+OI 8. 24E-07 1. SSE-OS 1. 29E-04 4. 65E-OI 

3.00E+OI 8. 35E-07 2. 37E-OS 1.24E-04 4.SSE-OI 

4.00E+Ol S.44E-07 3.I4E-OS 1. 19E-04 4. 45E-Ol 

5.00E+OI S.53E-07 3.9IE-OS 1.14E-04 4. 36E-OI 

6.00E+OI S.6IE-07 4. 66E-OS 1.lOE-04 4.26E-Ol 

7.00E+Ol 8. 69E-07 S.40E-OS I.06E-04 4.l7E-Ol 

8.00E+OI 8. 75E-07 6.14E-OS I.02E-04 4.0SE-OI 

9.00E+Ol 8.8lE-07 6. 86E-OS 9.S2E-OS 3.99E-OI 

1.OOE+02 8.S6E-07 7.S7E-OS 9. 46E-05 3.90E-OI 

2.00E+02 9.00E-07 1. 39E-04 6. 45E-05 3.13E-OI 

3.00E+02 S.6SE-07 1.88E-04 4.40E-OS 2.50E-Ol 

4.00E+02 8.02E-07 2.2IE-04 3.00E-05 1.99E-Ol 

5.00E+02 7.23E-07 2.4lE-04 2.0SE-OS 1.SSE-OI 

6.00E+02 6.3SE-07 2. 49E-04 1.40E-OS 1.25E-Ol 

7.00E+02 5. 53E-07 2. 48E-04 9.S3E-06 9. 93E-02 

8.00E+02 4.73E-07 2.40E-04 6.50E-06 7.85E-02 

9.00E+02 4.0IE-07 2. 26E-04 4. 44E-06 6.20E-02 

I.OOE+03 3.36E-07 2.lOE-04 3.03E-06 4.S9E-02 

2.00E+03 4.15E-OS 5.47E-05 6.6lE-08 4. 42E-03 

B-416 
CLASS Y AHAD = 1 MICRON STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 82E-03 3.04E-01 2. 58E-Ol 7.31E-02 6.39E-Ol 

2.00E-Ol 3. 76E-03 2. 85E-Ol 2. 17E-Ol 1.33E-Ol 6. 39E-Ol 

3.00E-Ol 3.71E-03 2.70E-01 1.82E-Ol 1.82E-01 6.38E-Ol 

4.00E-Ol 3. 68E-03 2.57E-Ol 1.53E-Ol 2.21E-Ol 6. 36E-Ol 

5.00E-Ol 3.66E-03 2. 47E-Ol 1.29E-Ol 2.52E-Ol 6. 32E-Ol 

6.00E-Ol 3. 65E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6. 27E-Ol 

7.00E-Ol 3. 64E-03 2.31E-Ol 9.12E-02 2.94E-Ol 6. 19E-Ol 

8.00E-Ol 3. 63E-03 2.24E-Ol 7. 67E-02 3.05E-Ol 6.10E-Ol 

9.00E-Ol 3.63E-03 2.19E-Ol 6.45E-02 3. 12E-01 5.99E-Ol 

1.00E+00 3.63E-03 2.13E-Ol 5.42E-02 3. 15E-Ol 5.87E-Ol 

2.00E+00 3. 63E-03 1.80E-Ol 9.59E-03 2.32E-Ol 4.26E-Ol 

3.00E+00 3. 64E-03 1. 65E-Ol 1.70E-03 1. 25E-Ol 2.95E-Ol 

4.00E+00 3. 65E-03 1.57E-Ol 3.00E-04 6.07E-02 2.21E-Ol 

5.00E+00 3. 66E-03 I.S3E-Ol S.30E-OS 2.86E-02 1.85E-Ol 

6.00E+00 3.66E-03 1.51E-Ol 9. 37E-06 1.34E-02 1.68E-Ol 

7.00E+00 3.67E-03 1.49E-Ol 1. 66E-06 6. 44E-03 1.60E-Ol 

8.00E+00 3. 67E-03 1.49E-Ol 2.93E-07 3. 18E-03 1.56E-Ol 

9.00E+00 3. 68E-03 1.48E-Ol 5. 17E-08 1.6SE-03 1.54E-Ol 

1.00E+Ol 3. 69E-03 1.48E-Ol O.OOE+OO 9.20E-04 1.53E-Ol 

2.00E+Ol 3.78E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1.50E-Ol 

3.00E+Ol 3.90E-03 1.45E-Ol O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+Ol 4.03E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.48E-Ol 

5.00E+Ol 4.16E-03 1.42E-Ol O.OOE+OO 2.26E-04 1.46E-Ol 

6.00E+Ol 4.30E-03 1.41E-Ol O.OOE+OO 2.23E-04 1.45E-Ol 

7.00E+Ol 4. 44E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+Ol 4. 59E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1.42E-Ol 

9.00E+Ol 4.73E-03 1. 36E-01 O.OOE+OO 2.14E-04 1.41E-Ol 

1.00E+02 4. 87E-03 1. 35E-Ol O.OOE+OO 2.11E-04 1.40E-Ol 

2.00E+02 6. 31E-03 1.22E-Ol O.OOE+OO 1.84E-04 1.28E-Ol 

3.00E+02 7. 74E-03 1.1OE-01 O.OOE+OO 1.60E-04 1. 18E-Ol 

4.00E+02 9. 15E-03 9.98E-02 O.OOE+OO 1.39E-04 1.09E-Ol 

5.00E+02 1.05E-02 9.06E-02 O.OOE+OO 1.21E-04 1.0IE-Ol 

6.00E+02 1. 18E-02 8. 23E-02 O.OOE+OO 1.0SE-04 9.42E-02 

7.00E+02 1. 31E-02 7.49E-02 O.OOE+OO 9. 18E-05 8.81E-02 

8.00E+02 1.43E-02 6. 83E-02 O.OOE+OO 7. 99E-OS 8.27E-02 

9.00E+02 I.S4E-02 6. 23E-02 O.OOE+OO 6. 96E-05 7. 79E-02 

1.00E+03 1.65E-02 5.70E-02 O.OOE+OO 6.06E-05 7. 36E-02 

2.00E+03 2. 34E-02 2.5SE-02 O.OOE+OO 1. 51E-05 4.89E-02 

3.00E+03 2. 48E-02 1. 34E-02 O.OOE+OO 3.78E-06 3.82E-02 

4.00E+03 2.34E-02 8. 25E-03 O.OOE+OO 9.46E-07 3. 16E-02 

5.00E+03 2.07E-02 5.92E-03 O.OOE+OO 2.37E-07 2. 67E-02 

7.00E+03 I.S0E-02 4. 27E-03 O.OOE+OO 1.48E-08 1. 93E ... 02 

8.00E+03 1.25E-02 4.00E-03 O.OOE+OO O.OOE+OO 1.6SE-02 

9.00E+03 1.04E-02 3. 87E-03 O.OOE+OO O.OOE+OO 1.42E-02 

1.00E+04 8.S5E-03 3.80E-03 O.OOE+OO O.OOE+OO 1.24E-02 

2.00E+04 1. 19E-03 3. 74E-03 O.OOE+OO O.OOE+OO 4. 93E-03 

B-417 
CLASS Y AMAD= 1 MICRON STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SXSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 8. 33E-05 1.04E-05 

2.00E-Ol 1.59E-04 2.10E-04 

3.00E-Ol 2. 18E-04 1.06E-03 

4.00E-Ol 2. 63E-04 3.07E-03 

5.00E-Ol 2. 98E-04 6. 67E-03 

6.00E-Ol 3. 25E-04 1.21E-02 

7.00E-Ol 3. 46E-04 1. 94E-02 

8.00E-Ol 3. 62E-04 2. 86E-02 

9.00E-Ol 3. 76E-04 3. 96E-02 

1.00E+OO 3. 86E-04 3. 86E-04 5.21E-02 5.21E-02 

2.00E+OO 4.42E-05 4.30E-04 1.61E-Ol 2. 13E-Ol 

3.00E+OO 1.74E-05 4. 48E-04 1.31E-Ol 3. 44E-Ol 

4.00E+OO 1.43E-05 4. 62E-04 7.36E-02 4.17E-Ol 

5.00E+OO 1.32E-05 4. 75E-04 3.64E-02 4. 54E-Ol 

6.00E+OO 1. 24E-05 4. 88E-04 1.73E-02 4.71E-Ol 

7.00E+OO 1.18E-05 4. 99E-04 8.l3E-03 4. 79E-Ol 

8.00E+OO 1. 12E-05 5.11E-04 3. 88E-03 4. 83E-Ol 

9.00E+OO 1.06E-05 5.21E-04 1. 91E-03 4. 85E-Ol 

1.00E+Ol 1.02E-05 5.31E-04 9.85E-04 4.86E-Ol 

2.00E+Ol 6.77E-06 6. 12E-04 1.36E-04 4. 88E-Ol 

3.00E+Ol 5.lOE-06 6.70E-04 1.33E-04 4.89E-Ol 

4.00E+Ol 4. 28E-06 7. 16E-04 1.31E-04 4.91E-Ol 

5.00E+Ol 3. 89E-06 7.56E-04 1.29E-04 4.92E-Ol 

7.00E+Ol 3. 65E-06 8.31E-04 1. 26E-04 4. 95E-Ol 

8.00E+Ol 3.63E-06 8. 67E-04 1.24E-04 4. 96E-Ol 

9.0QE+Ol 3. 64E-06 9.04E-04 1. 22E-04 4. 97E-Ol 

1.00E+02 3. 67E-06 9.40E-04 1.21E-04 4. 98E-Ol 

2.00E+02 4.00E-06 1.32E-03 1.05E-04 5.10E-Ol 

3.00E+02 4.3lE-06 1. 74E-03 9.14E-05 5.19E-Ol 

4.00E+02 4. 58E-06 2. 18E-03 7. 96E-05 5.28E-Ol 

5.00E+02 4. 83E-06 2. 66E-03 6.93E-05 5. 35E-Ol 

7.00E+02 5. 23E-06 3. 66E-03 5. 25E-05 5.47E-Ol 

8.00E+02 5.40E-06 4.20E-03 4.57E-05 5. 52E-Ol 

9.00E+02 5.55E-06 4. 74E-03 3. 98E-05 5. 57E-Ol 

1.00E+03 5. 67E-06 5.30E-03 3.47E-05 5.60E-Ol 

2.00E+03 6.11E-06 1. 13E-02 8. 66E-06 5. 79E-Ol 

3.00E+03 5. 73E-06 1.72E-02 2.17E-06 5. 84E-Ol 

4.00E+03 5.05E-06 2. 27E-02 5.41E-07 5. 85E-Ol 

5.00E+03 4. 32E-06 2. 73E-02 1.35E-07 5. 85E-Ol 

7.00E+03 3.03E-06 3. 46E-02 O.OOE+OO 5. 85E-Ol 

8.00E+03 2.5lE-06 3. 74E-02 O.OOE+OO 5. 85E-Ol 

9.00E+03 2.07E-06 3. 97E-02 O.OOE+OO 5. 85E-Ol 

1.00E+04 . 1.70E-06 4.15E-02 O.OOE+OO 5.85E-Ol 

2.00E+04 2. 36E-07 4.90E-02 O.OOE+OO 5.85E-Ol 

B-418 
CLASS Y AMAD == 1 MICRON STABLE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

, SINGLE INTAKE --------------------------------------------------------

SYSTEtUC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.82E-03 3.04E-01 2. 58E-01 7.31E-02 6. 39E-01 

2.00E-01 3. 76E-03 2.85E-01 2. 17E-Ol 1.33E-Ol 6.39E-Ol 

3.00E-Ol 3. 72E-03 2.70E-01 1. 82E-Ol. 1.82E-Ol 6.38E-01 

4.00E-Ol 3.69£-03 2. 57E-Ol 1. 53E-01 2.21E-01 6. 36E-01 

5.00E-01 3.67E-03 2.47E-01 1.29E-01 2. 52E-01 6.32E-Ol 

6.00£-01 3. 66E-03 2. 38E-01 1.08E-01 2.76E-Ol 6. 27E-Ol 

7.00E-01 3. 65E-03 2.31E-Ol 9.12E-02 2.94E-Ol 6. 19E-Ol 

8.00E-01 3. 65E-03 2. 24E-01 7. 67E-02 3.05E-01 6.lOE-Ol 

9.00E-01 3. 64E-03 2.19E-Ol 6. 45E-02 3.12E-01 5. 99E-01 

1.00E+00 3. 64E-03 2. 13E-O 1 5.42E-02 3. 15E-Ol 5. 87E-01 

2.00E+00 3.66E-03 1.80E-01 9. 59E-03 2. 32E-Ol 4.26E-01 

3.00E+00 3. 68E-03 1. 65E-01 1.70E-03 1.25E-01 2. 95E-01 

4.00E+00 3.70E-03 1.57E-01 3.00E-04 6.07E-02 2.21E-01 

5.00E+00 3.71E-03 1. 53E-01 5.30E-05 2. 86E-02 1. 85E-01 

6.00E+00 3.73E-03 1.51E-01 9. 37E-06 1.34E-02 1. 68E-01 

7.00E+00 3. 75E-03 1. 49E-01 1. 66E-06 6.44E-03 1.60E-01 

8.00E+00 3. 76E-03 1.49E-01 2. 93E-07 3. 18E-03 1.56E-01 

9.00E+00 3. 78E-03 1.48E-Ol 5. 17E-08 1. 65E-03 1. 54E-01 

1.00E+01 3. 79E-03 1. 48E-01 O.OOE+OO 9.20E-04 1.53E-Ol 

2.00E+Ol 3. 94E-03 1.46E-01 O.OOE+OO 2. 36E-04 1. 51E-01 

3.00E+01 4.09E-03 1.45E-01 O.OOE+OO 2. 32E-04 1.49E-01 

4.00E+01 4. 24E-03 1.43E-01 O.OOE+OO 2. 29E-04 1.48E-01 

5.00E+01 4. 39E-03 1.42E-01 O.OOE+OO 2. 26E-04 1.47E-01 

6.00E+Ol 4. 54E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1. 45E-Ol 

7.00E+01 4. 69E-03 1. 39E-01 O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+01 4.84E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1.43E-Ol 

9.00E+01 4. 99E-03 1.36E-01 O.OOE+OO 2. 14E-04 1.41E-01 

1.00E+02 5. 15E-03 1. 35E-Ol O.OOE+OO 2. 11E-04 1.40E-01 

2.00E+02 6. 67E-03 1. 22E-01 O.OOE+OO 1. 84E-04 1.29E-Ol 

3.00E+02 8. 18E-03 1.lOE-Ol O.OOE+OO 1.60E-04 1. 19E-Ol 

4.00E+02 9.67E-03 9. 98E-02 O.OOE+OO 1.39E-04 1.lOE-01 

5.00E+02 1.11E-02 9.06E-02 O.OOE+OO 1.21E-04 1.02E-01 

6.00E+02 1.25E-02 8. 23E-02, O.OOE+OO 1.05E-04 9.49E-02 

7.00E+02 1. 39E-02 7. 49E-02 O.OOE+OO 9. 18E-05 8. 89E-02 

8.00E+02 1.51E-02 6. 83E-02 O.OOE+OO 7.99E-05 8. 35E-02 

9.00E+02 1. 63E-02 6. 23E-02 O.OOE+OO 6. 96E-05 7. 88E-02 ,. 1.00E+03 1.75E-02 5.70E-02 O.OOE+OO 6.06E-05 7.45E-02 

2.00E+03 2.47E-02 2. 55E-02 O.OOE+OO 1. 51E-05 5.02E-02 

3.00E+03 2.63E-02 1. 34E-02 O.OOE+OO 3. 78E-06 3.97E-02 

4.00E+03 2. 48E-02 8. 25E-03 O.OOE+OO 9. 46E-07 3.30E-02 

5.00E+03 2.20E-02 5. 92E-03 O.OOE+OO 2.37E-07 2. 79E-02 

7.00E+03 1. 59E-02 4.27E-03 O.OOE+OO 1. 48E-08 2.02E-02 

8.00E+03 1.32E-02 4.00E-03 O.OOE+OO O.OOE+OO 1.72E-02 

9.00E+03 1.10E-02 3. 87E-03 O.OOE+OO O.OOE+OO 1. 48E-02 

1.00E+04 9.06E-03 3.80E-03 O.OOE+OO O.OOE+OO 1.29E-02 

2.00E+04 1.26E-03 3. 74E-03 O.OOE+OO O'.OOE+OO 5.00E-03 

B-419 
CLASS Y AMAD = 1 KICRON STABLE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 8. 22E-OS 1.04E-OS 

2.00E-Ol I.S7E-04 2.lOE-04 

3.00E-Ol Z.14E-04 1.06E-03 

4.00E-Ol 2.S8E-04 3.07E-03 

S.OOE-Ol 2. 91E-04 6.67E-03 

6.00E-Ol 3. 17E-04 1.21E-02 

7.00E-Ol 3.37E-04 1. 94E-02 

8.00E-Ol 3.S2E-04 2. 86E-02 

9.00E-Ol 3. 64E-04 3.96E-02 

1.00E+OO 3. 73E-04 3. 73E-04 S.21E-02 S.21E-02 

2.00E+OO 3. 16E-OS 4.0SE-04 1.61E-Ol 2.l3E-OI 

3.00E+OO S.SSE-06 4.10E-04 1.31E-Ol 3.44E-Ol 

4.00E+OO 3.09E-06 4. 13E-04 7.36E-02 4.17E-Ol 

S.OOE+OO 2. 69E-06 4. 16E-04 3. 64E-02 4.S4E-Ol 

6.00E+OO 2.S7E-06 4. 19E-04 1.73E-02 4.71E-Ol 

7.00E+OO 2.S2E-06 4.21E-04 8.l3E-03 4. 79E-Ol 

8.00E+OO 2. SOE-06 4.24E-04 3. 88E-03 4.83E-Ol 

9.00E+OO 2.S0E-06 4.26E-04 1.91E-03 4.8SE-Ol 

1.00E+Ol 2.49E-06 4. 29E-04 9.8SE-04 4.86E-Ol 

2.00E+Ol 2.S2E-06 4.S4E-04 1. 36E-04 4.88E-Ol 

3.00S+01 2.S6E-06 4. 79E-04 1.33E-04 4. 89E-Ol 

4.00E+Ol 2.60E-06 S.OSE-04 1.31E-04 4.91E-Ol 

S.OOE+Ol 2. 64E-06 S.31E-04 1.29E-04 4. 92E-Ol 

7.00E+Ol 2.71E-06 S.8SE-04 1. 26E-04 4.9SE-Ol 

8.00E+Ol 2.74E-06 6. 12E-04 1.24E-04 4.96E-Ol 

9.00E+Ol 2. 78E-06 6.40E-04 1. 22E-04 4.97E-Ol 

1.00E+02 2.82E-06 6.68E-04 1.21E-04 4.98E-Ol 

2.00E+02 3. 16E-06 9. 66E-04 1.0SE-04 S.lOE-OI 

3.00E+02 3.47E-06 1.30E-03 9.14E-OS S.19E-Ol 

4.00E+02 3. 76E-06 1. 66E-03 7. 96E-OS S.28E-Ol 

S.OOE+02 4.03E-06 2.0SE-03 6.93E-OS S.3SE-Ol 

7.00E+02 4.S0E-06 2.91E-03 S.2SE-OS S.47E-Ol 

8.00E+02 4.71E-06 3.37E-03 4.S7E-OS S.S2E-Ol 

9.00E+02 4.89E-06 3.8SE-03 3. 98E-OS S.S7E-Ol 

1.OOE+03 S.06E-06 4.34E-03 3. 47E-OS S.60E-Ol 

2.00E+03 S.88E-06 9.93E-03 8. 66E-06 S.79E-Ol 

3.00E+03 S.74E-06 1.S8E-02 2.17E-06 S.84E-Ol 

4.00E+03 S.18E-06 2.13E-02 S.41E-07 S.8SE-Ol 

S.OOE+03 4.49E-06 2.61E-02 1.3SE-07 S.8SE-Ol 

7.00E+03 3. 18E-06 3. 38E-02 O.OOE+OO S.8SE-Ol 

8.00E+03 2. 64E-06 3. 67E-02 O.OOE+OO S.8SE-Ol 

9.00E+03 2.18E-06 3.91E-02 O.OOE+OO S.8SE-Ol 

1.00E+04 1.80E-06 4.10E-02 O.OOE+OO S.8SE-Ol 

2.00E+04 2.S0E-07 4. 89E-02 O.OOE+OO S.8SE-Ol 

B-420 
CLASS Y AHAD - 1 KICRON BAI..'FLIFI= 9.58E+02 DAYS PROMETHIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 82E-03 3.04E-01 2.58E-01 7.31E-02 6.39E-Ol 

2.00E-01 3. 76E-03 2. 85E-01 2. 17E-01 1. 33E-01 6. 39E-01 

3.00E-01 3. 72E-03 2.70E-01 1.82E-01 1.82E-0l 6.38E-01 

4.00E-01 3. 69E-03 2. 57E-Ol 1. 53E-OI 2.2IE-01 6. 36E-01 

S.00E-01 3. 67E-03 2.47E-01 1.29E-01 2.S2E-01 6. 32E-01 

6.00E-01 3. 66E-03 2. 38E-01 1.08E-01 2. 76E-01 6. 26E-01 

7.00E-01 3.65E-03 2. 31E-01 9. 12E-02 2. 93E-01 6. 19E-01 

8.00E-01 3. 64E-03 2. 24E-01 7. 67E-02 3.05E-OI 6.lOE-01 

9.00E-01 3. 64E-03 2. 18E-OI 6. 45E-02 3. 12E-0l 5. 99E-01 

1.00E+00 3. 64E-03 2.DE-01 5. 42E-02 3. 15E-01 S.86E-01 

2.00E+00 3. 65E-03 1.80E-OI 9. 58E-03 2.32E-01 4. 25E-01 

3.00E+00 3. 67E-03 1. 64E-01 1. 69E-03 1.2SE-01 2. 94E-01 

4.00E+00 3. 69E-03 I. 56E-Ol 2.99E-04 6.05E-02 2.21E-0l 

5.00E+00 3.70E-03 1. 52E-OI 5. 28E-05 2. 85E-02 1. 84E-01 

6.00E+00 3. 71E-03 1.50E-0l 9.32E-06 1.34E-02 1.67E-0l 

7.00:6+00 3. 73E-03 1. 49E-01 1. 65E-06 6.40E-D3 1. 59E-01 

8.00E+00 3. 74E-03 1.48E-01 2.91E-07 3. 16E-03 1.55E-01 

9.00E+00 3. 75E-03 1. 47E-01 5. 14E-08 1. 64E-03 I. 53E-01 

1.00E+01 3. 76E-03 1.47E-01 O.OOE+OO 9. 14E-04 1.52E-OI 

2.00E+01 3. 88E-03 1. 44E-OI O.OOE+OO 2. 33E-04 I. 48E-01 

3.00E+01 4.00E-03 1.42E-01 O.OOE+OO 2. 27E-04 1. 46E-01 

4.00E+01 4. 12E-03 1. 39E-01 O.OOE+OO 2. 23E-04 1. 44E-OI 

5.00E+01 4.23E-03 1.37E-01 O.OOE+OO 2. 18E-04 1.41E-0l 

6.00E+01 4. 35E-03 I. 35E-OI O.OOE+OO 2. 13E-D4 1. 39E-01 

7.00E+OI 4. 46E-03 1.32E-01 O.OOE+OO 2.09E-04 1.37E-01 

8.00E+01 4.S'1E-03 1.30E-OI O.OOE+OO 2.05E-04 1. 35E-01 

9.00E+01 4. 68E-03 1.28E-01 O.OOE+OO 2.00E-04 1. 33E-01 

1.00E+02 4. 79E-03 I. 25E-01 O.OOE+OO 1. 96E-04 1.30E-OI 

2.00E+02 5. 77E-03 1.05E-01 O.OOE+OO 1.59E-04 1.UE-01 

3.00E+02 6. 58E-03 8. 87E-02 O.OOE+OO I. 29E-04 9. 54E-02 

4.00E+02 7.24E-03 7.47E-02 O.OOE+OO 1.04E-04 8.2IE-02 

5.00E+02 7. 75E-03 6. 31E-02 O.OOE+OO 8. 43E-05 7.09E-02 

6.00E+02 8. 11E-03 5. 33E-02 O.OOE+OO 6. 83E-05 6. 15E-02 

7.00E+02 8.35E-03 4. 51E-02 O.OOE+OO 5. 53E-05 S.35E-02 

8.00E+02 8. 48E-03 3.83E-02 O.OOE+OO 4.48E-05 4.68E-02 

9.00E+02 8. 52E-03 3.25E-02 O.OOE+OO 3. 63E-05 4.10E-02 

1.00E+03 8. 47E-03 2. 76E-02 O.OOE+OO 2. 94E-05 3.6IE-02 , .' 2.00E+03 5. 82E-03 5. 99E-03 O.OOE+OO 3. 56E-06 1. 18E-02 

3.00E+03 3.00E-03 1. S2E-03 O.OOE+OO 4.31E-07 4. 52E-03 

4.00E+03 1. 37E-03 4.56E-04 O.OOE+OO S.23E-D8 1. 82E-03 

5.00E+03 5. 89E-04 1. 59E-04 O.OOE+OO O.OOE+OO 7. 47E-04 

6.00E+03 2.45E-04 6. 25E-OS O.OOE+OO O.OOE+OO 3.07E-04 

7.00E+03 1.00E-04 2. 69E-OS O.OOE+OO O.OOE+OO 1. 27E-04 

8.00E+03 4.05E-05 1. 22E-05 O.OOE+OO O.OOE+OO 5. 27E-05 

9.00E+03 1. 63E-05 5. 73E-06 O.OOE+OO O.OOE+OO 2.20E-OS 

1.00E+04 6.50E-06 2. 73E-06 O.OOE+OO O.OOE+OO 9. 23E-06 

B-421 
CLASS Y AMA.D = 1 HICRON BALFLlFE= 9.58E+02 DAYS PRO.HETB.IUH 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- -------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol B.22E-OS 1.04E-OS 

2.00E-Ol 1.S7E-04 2.lOE-04 

3.00E-Ol 2.l4E-04 1.06E-03 

4.00E-Ol 2.SBE-04 3.07E-03 

S.OOE-Ol 2.9lE-04 6. 66E-03 

6.00E-Ol 3.17E-04 1.2lE-02 

7.00E-Ol 3. 36E-04 1.94E-02 

B.OOE-Ol 3.S2E-04 2.B6E-02 

9.00E-Ol 3.64E-04 3. 96E-02 

1.OOE+OO 3. 73E-04 3.73E-04 S.20E-02 S.20E-02 

2.00E+OO 3.lSE-OS 4.04E-04 1.6lE-Ol 2.l3E-Ol 

3.00E+OO S.S4E-06 4.09E-04 1.3lE-Ol 3. 43E-Ol 

4.00E+OO 3.0BE-06 4.l2E-04 7.34E-02 4.l6E-Ol 

S.OOE+OO 2.6BE-06 4.lSE-04 3. 63E-02 4.S2E-Ol 

6.00E+OO 2.S6E-06 4.l7E-04 1.72E-02 4.69E-Ol 

7.00E+OO 2.SlE-06 4.l9E-04 B.09E-03 4.17E-Ol 

B.OOE+OO 2. 49E-06 4.2lE-04 3.B6E-03 4.BOE-Ol 

9.00E+OO 2.4BE-06 4. 23E-04 1.90E-03 4.B2E-Ol 

1.OOE+Ol 2.4BE-06 4.2SE-04 9.7BE-04 4.B2E-Ol 

2.00E+Ol 2. 49E-06 4. 47E-04 1. 34E-04 4. BlE-Ol . 

3.00E+Ol 2.SlE-06 4. 69E-04 1.30E-04 4. 79E-Ol 

4.00E+Ol 2.S2E-06 4.9lE-04 1.27E-04 4. 17E-Ol 

S.OOE+Ol 2.S4E-06 S.12E-04 1.2SE-04 4.7SE-Ol 

6.00E+Ol 2.S6E-06 S.34E-04 1. 22E-04 4. 12E-Ol 

7.00E+Ol 2.S7E-06 S. S6E-04 1.20E-04 4.70E-Ol 

B.OOE+Ol 2.S9E-06 S.17E-04 1.17E-04 4.6BE-Ol 

9.00E+Ol 2.60E-06 S.99E-04 1.lSE-04 4.66E-Ol 

1.OOE+02 2.62E-06 6.2lE-04 1.12E-04 4. 63E-Ol 

2.00E+02 2. 73E-06 B.36E-04 9.09E-OS 4.4lE-Ol 

3.00E+02 2. 79E-06 1.04E-03 7.36E-OS 4.lBE-Ol 

4.00E+02 2.B2E-06 1.24E-03 S.96E-OS 3.9SE-Ol 

S.OOE+02 2.BlE-06 1.43E-03 4.B3E-OS 3. 73E-Ol 

6.00E+02 2. 77E-06 1.60E-03 3.9lE-OS 3. SlE-Ol 

7.00E+02 2.71E-06 1.7SE-03 3.l6E-OS 3.30E-Ol 

B.OOE+02 2. 64E-06 1.B9E-03 2.S6E-OS 3.09E-Ol , '. 9.00E+02 2.SSE-06 2.0lE-03 2.07E-OS 2.90E-Ol 

1.OOE+03 2.4SE-06 2.11E-03 1.6BE-OS 2.12E-Ol 

2.00E+03 1.3BE-06 2. 33E-03 2.04E-06 1. 36E-Ol 

3.00E+03 6.S5E-07 1. BOE-03 2.47E-07 6.6SE-02 . 

4.00E+03 2.B7E-07 1.lBE-03 2. 99E-OB 3. 23E-02 

S.OOE+03 1.20E-07 7.00E-04 O.OOE+OO 1. S7E-02 

6.00E+03 4.9SE-OB 3. 93E-04 O.OOE+OO 7.60E-03 

7.00E+03 2.0lE-OB 2.l3E-04 O.OOE+OO 3. 69E-03 

B-422 
CLASS Y AMAD == 1 MICRON STABLE YTrERBIUH 173 

TIt;tE AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 59E-03 3.04E-Ol 2.58E-Ol 7.31E-02 6.39E-Ol 

2.00E-Ol 3. 32E-03 2. 85E-Ol 2. 17E-Ol 1. 33E-Ol 6. 38E-Ol 

3.00E-Ol 3.1OE-03 2.70E-Ol 1.82E-Ol 1.82E-Ol 6. 37E-Ol 

4.00E-Ol 2. 93E-03 2. 57E-Ol 1. 53E-Ol 2.21E-Ol 6.35E-Ol 

5.00E-Ol 2. 79E-03 2.47E-Ol 1.29E-01 2. 52E-Ol 6.31E-Ol 

6.00E-Ol 2. 68E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6. 26E-Ol 

7.00E-Ol 2.60E-03 2.31E-Ol 9. 12E-02 2.94E-Ol 6. 18E-Ol 

8.00E-Ol 2. 53E-03 2. 24E-Ol 7. 67E-02 3.05E-Ol 6.09E-Ol 

9.00E-Ol 2.47E-03 2. 19E-Ol 6. 45E-02 3.12E-01 5. 98E-Ol 

1.00E+00 2. 43E-03 2. 13E-Ol 5. 42E-02 3. 15E-Ol 5. 85E-Ol 

2.00E+00 2. 27E-03 1.80E-Ol 9.59E-03 2. 32E-Ol 4.25E-Ol 

3.00E+00 2. 26E-03 1. 65E-Ol 1.70E-03 1.25E-Ol 2. 94E-Ol 

4.00E+00 2.27E-03 1.57E-Ol 3.00E-04 6.07E-02 2.20E-Ol 

5.00E+00 2. 27E-03 1. 53E-Ol 5.30E-05 2.86E-02 1. 84E-Ol 

6.00E+00 2.28E-03 1.51E-Ol 9.37E-06 1.34E-02 1.66E-Ol 

7.00E+00 2. 28E-03 1.49E-Ol 1. 66E-06 6. 44E-03 1. 58E-Ol 

8.00E+00 2. 29E-03 1.49E-Ol 2.93E-07 3. 18E-03 1. 54E-Ol 

9.00E+00 2. 29E-03 1.48E-Ol 5. 17E-08 1. 65E-03 1. 52E-Ol 

1.00E+Ol 2.30E-03 1.48E-Ol O.OOE+OO 9.20E-04 1.51E-Ol 

2.00E+Ol 2. 37E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1. 49E-Ol 

3.00E+Ol 2. 45E-03 1.45E-01 O.OOE+OO 2.32E-04 1.48E-01 

4.00E+Ol 2. 53E-03 1. 43E-Ol O.OOE+OO 2. 29E-04 1.46E-Ol 

5.00E+Ol 2. 62E-03 1.42E-01 O.OOE+OO 2.26E-04 1.45E-Ol 

6.00E+Ol 2. 71E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1.43E-Ol 

7.00E+Ol 2.80E-03 1.39E-Ol O.OOE+OO 2.20E-04 1. 42E-Ol 

8.00E+Ol 2. 89E-03 1.38E-Ol O.OOE+OO 2. 17E-04 1.41E-Ol 

9.00E+Ol 2. 98E-03 1.36E-Ol O.OOE+OO 2. 14E-04 1.39E-Ol 

1.00E+02 3.07E-03 1.35E-Ol O.OOE+OO 2.11E-04 1. 38E-Ol 

2.00E+02 3.97E-03 1.22E-Ol O.OOE+OO 1.84E-04 1.26E-Ol 

3.00E+02 4.87E-03 1.1OE-Ol O.OOE+OO 1.60E-04 I. 15E-Ol 

4.00E+02 5. 76E-03 9.98E-02 O.OOE+OO 1.39E-04 1.06E-Ol 

5.00E+02 6. 62E-03 9.06E-02 O.OOE+OO 1. 21E-04 9. 73E-02 

6.00E+02 7. 45E-03 8. 23E-02 O.OOE+OO 1.05E-04 8. 99E-02 

7.00E+02 8. 25E-03 7.49E-02 O.OOE+OO 9. 18E-05 8. 32E-02 

8.00E+02 9.01E-03 .6.83E-02 O.OOE+OO 7.99E-05 7. 74E-02 

9.00E+02 9.72E-03 6. 23E-02 O.OOE+OO 6. 96E-05 7. 21E-02 

1.00E+03 1.04E-02 5.70E-02 O.OOE+OO 6.06E-05 6. 75E-02 

2.00E+03 1. 47E-02 2. 55E-02 O.OOE+OO 1.51E-05 4.02E-02 

3.00E+03 1.56E-02 1.34E-02 O.OOE+OO 3. 78E-06 2.90E-02 

4.00E+03 1.47E-02 8. 25E-03 O.OOE+OO 9.46E-07 2.30E-02 

5.00E+03 1.31E-02 5.92E-03 O.OOE+OO 2.37E-07 1.90E-02 

7.00E+03 9.45E-03 4. 27E-03 O.OOE+OO 1.48E-08. 1. 37E-02 

8.00E+03 7. 88E-03 4.00E-03 O.OOE+OO O.OOE+OO 1. 19E-02 

9.00E+03 6. 52E-03 3. 87E-03 O.OOE+OO O.OOE+OO 1.04E-02 

1.00E+04 5. 38E-03 3.80E-03 O.OOE+OO O.OOE+OO 9.19E-03 

2.00E+04 7.50E-04 3. 74E-03 O.OOE+OO O.OOE+OO 4. 49E-03 

B-423 
CLASS Y AKAD = 1 MICRON STABLE YTTERBIUM 173 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.06E-04 l.04E-OS 

2.00E-Ol 5. 98E-04 2.l0E-04 

3.00E-Ol 8. 32E-04 1.06E-03 

4.00E-Ol I.02E-03 3.07E-03 

5.00E-OI 1.17E-03 6.67E-03 

6.00E-OI 1.29E-03 1.2lE-02 

7.00E-OI 1.39E-03 1.94E-02 

8.00E-OI 1.47E-03 2. 86E-02 

9.00E-OI 1. 54E-03 3.96E-02 

I.OOE+OO I.59E-03 1. 59E-03 5.2IE-02 5.2IE-02 

2.00E+OO 2.04E-04 I.79E-03 I.6IE-Ol 2.13E-OI 

3.00E+OO 3. 82E-05 1. 83E-03 I.3IE-Ol 3. 44E-OI 

4.00E+OO 1.7IE-05 1.8SE-03 7. 36E-02 4.I7E-Ol 

S.OOE+OO 1. 36E-05 1. 86E-03 3. 64E-02 4. 54E-OI 

6.00E+OO 1.26E-05 1.87E-03 I.73E-02 4.7IE-OI 

7.00E+OO 1.2IE-OS I.89E-03 8.l3E-03 4. 79E-OI 

8.00E+OO 1.18E-OS 1.90E-03 3. 88E-03 4.83E-OI 

9.00E+OO 1.ISE-OS 1.9IE-03 1.9IE-03 4.8SE-OI 

I.OOE+OI 1.13E-05 I. 92E-03 9.85E-04 4.86E-Ol 

2.00E+OI 9. 95E-06 2.02E-03 1. 36E-04 4. 88E-OI 

3.00E+OI 9. 32E-06 2. 12E-03 I. 33E-04 4. 89E-OI 

4.00E+OI 9.03E-06 2.2lE-03 1.3IE-04 4.9lE-Ol 

5.00E+Ol 8.9lE-06 2.30E-03 1.29E-04 4.92E-Ol 

7.00E+Ol 8. 87E-06 2. 48E-03 I. 26E-04 4. 95E-OI 

8.00E+Ol 8.90E-06 2. 57E-03 1.24E-04 4. 96E-OI 

9.00E+Ol 8. 93E-06 2. 66E-03 1. 22E-04 4. 97E-Ol 

I.OOE+02 8. 97E-06 2. 75E-03 1.2lE-04 4. 98E-Ol 

2.00E+02 9. 33E-06 3. 66E-03 1.OSE-04 5.l0E-Ol 

3.00E+02 9. 58E-06 4.6lE-03 9.l4E-05 S.I9E-OI 

4.00E+02 9. 74E-06 5. 57E-03 7. 96E-05 5. 28E-Ol 

5.00E+02 9.83E-06 6.S5E-03 6.93E-05 5. 35E-OI 

7.00E+02 9. 82E-06 8.52E-03 5. 25E-05 S.47E-Ol 

8.00E+02 9. 74E-06 9.50E-03 4. 57E-OS 5.52E-Ol 

9.00E+02 9. 63E-06 I.05E-02 3. 98E-OS 5. 57E-OI 

1.00E+03 9. 49E-06 l.14E-02 3.47E-05 5.60E-OI 

2.00E+03 7.48E-06 2.00E-02 8. 66E-06 5. 79E-OI 

3.00E+03 5. 59E-06 2.65E-02 2.l7E-06 5. 84E-Ol 

4.00E+03 4. 22E-06 3.I3E-02 5.4lE-07 5. 85E-Ol 

5.00E+03 3. 25E-06 3.50E-02 1.3SE-07 5.85E-Ol 

7.00E+03 2.04E-06 4.02E-02 O.OOE+OO 5. 85E-Ol 

8.00E+03 1. 64E-06 4.20E-02 O.OOE+OO 5.85E-Ol 

9.00E+03 1. 33E-06 4. 35E-02 O.OOE+OO 5. 85E-Ol 

1.OOE+04 I.09E-06 4. 47E-02 O.OOE+OO 5. 85E-0l 

2.00E+04 1. 49E-07 4. 94E-02 O.OOE+OO 5. 85E-Ol 

B-424 
CLASS Y AMAD = 1 MICRON STABLE LUTETIUM 175 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.64E-03 3.04E-01 2.S8E-Ol 7.31E-02 6. 39E-01 

2.00E-Ol 3.41E-03 2. 85E-01 2.17E-01 1. 33E-01 6. 38E-01 

3.00E-01 3. 23E-03 2.70E-01 1.82E-Ol 1.82E-Ol 6.37E-Ol 

4.00E-01 3.09E-03 2.S7E-Ol I.S3E-Ol 2.21E-Ol 6.35E-Ol 

5.00E-01 2. 98E-03 2.47E-Ol 1.29E-Ol 2.S2E-Ol 6.31E-Ol 

6.00E-01 2.89E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6.26E-Ol 

7.00E-Ol 2. 82E-03 2. 31E-Ol 9.12E-02 2. 94E-Ol 6.19E-Ol 

8.00E-Ol 2. 76E-03 2.24E-Ol 7. 67E-02 3.05E-Ol 6.09E-01 

9.00E-Ol 2.72E-03 2.19E-01 . 6.4SE-02 3. 12E-Ol S.98E-01 

1.OOE+OO 2. 68E-03 2. 13E-Ol 5. 42E-02 3.1SE-01 5.86E-01 

2.00E+OO 2.S6E-03 1.80E-Ol 9.S9E-03 2.32E-01 4.2SE-0l 

3.00E+OO 2.S6E-03 1.6SE-Ol 1.70E-03 1.2SE-Ol 2. 94E-Ol 

4.00E+OO 2.S7E-03 1.S7E-Ol 3.00E-04 6.07E-02 2.20E-Ol 

5.00E+OO 2.S8E-03 l.53E-Ol 5.30E-OS 2. 86E-02 1. 84E-Ol 

6.00E+OO 2. 59E-03 I.S1E-01 9.37E-06 1.34E-02 1.67E-01 

7.00E+OO 2.60E-03 1.49E-Ol 1. 66E-06 6. 44E-03 I.SSE-Ol 

8.00E+OO 2.61E-03 1.49E-Ol 2.93E-07 3.1SE-03 I.S5E-01 

9.00E+OO 2.61E-03 1.4SE-01 S.17E-OS 1.6SE-03 1.S3E-OI 

1.00E+Ol 2. 62E-03 1.4SE-Ol O.OOE+OO 9.20E-04 I.S2E-01 

2.00E+Ol 2. 72E-03 1. 46E-Ol O.OOE+OO 2. 36E-04 1.49E-Ol 

3.00E+Ol 2.S2E-03 1.4SE-Ol O.OOE+OO 2.32E-04 1.4SE-Ol 

4.00E+Ol 2. 93E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.47E-Ol 

S.OOE+01 3.03E-03 1.42E-Ol O.OOE+OO 2. 26E-04 1.4SE-Ol 

6.00E+01 3.13E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1.44E-01 

7.00E+01 3. 24E-03 1.39E-01 O.OOE+OO 2.20E-04 1.43E-01 

S.OOE+01 3. 34E-03 1.3SE-Ol O.OOE+OO 2. 17E-04 l.41E-Ol 

9.00E+Ol 3. 44E-03 1.36E-Ol O.OOE+OO 2.14E-04 1.40E-01 

1.00E+02 3.SSE-03 1.3SE-Ol O.OOE+OO 2. 11E-04 1. 39E-Ol 

2.00E+02 4.60E-03 1. 22E-Ol O.OOE+OO I.S4E-04 1.27E-Ol 

3.00E+02 5. 64E-03 1.lOE-OI O.OOE+OO 1.60E-04 1. 16E-Ol 

4.00E+02 6.67E-03 9.9SE-02 O.OOE+OO 1.39E-04 1.07E-Ol 

5.00E+02 7.67E-03 9.06E-02 O.OOE+OO 1.21E-04 9.S4E-02 

6.00E+02 S.63E-03 S.23E-02 O.OOE+OO 1.OSE-04 9.10E-02 

7.00E+02 9.S6E-03 7.49E-02 O.OOE+OO 9.1SE-OS 8.4SE-02 

S.OOE+02 1.04E-02 6. 83E-02 O.OOE+OO 7.99E-OS 7.S8E-02 

9.00E+02 1.13E-02 6.23E-02 O.OOE+OO 6. 96E-OS 7. 37E-02 

1.OOE+03 I.20E-02 S.70E-02 O.OOE+OO 6.06E-OS 6.91E-02 

2.00E+03 I.70E-02 2.5SE-02 O.OOE+OO 1.51E-OS 4.2SE-02 

3.00E+03 I.81E-02 1.34E-02 O.OOE+OO 3.7SE-06 3.1SE-02 

4.00E+03 I.71E-02 S.2SE-03 O.OOE+OO 9. 46E-07 2. 53E-02 

5.00E+03 I.51E-02 S.92E-03 O.OOE+OO 2. 37E-07 2.10E-02 

7.00E+03 1.09E-02 4. 27E-03 O.OOE+OO 1.4SE-OS 1. 52E-02 

S.OOE+03 9.13E-03 4.00E-03 O.OOE+OO O.OOE+OO 1.31E-02 

9.00E+03 7.S6E-03 3.S7E-03 O.OOE+OO O.OOE+OO 1. 14E-02 

1.00E+04 6. 24E-03 3.80E-03 O.OOE+OO O.OOE+OO 1.OOE-02 

2.00E+04 S.69E-04 3. 74E-03 O.OOE+OO O.OOE+OO 4.61E-03 

B-425 
CLASS Y AHAD = 1 MICRON STABLE WTETIUM 175 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 58E-04 1.04E-05 

2.00E-Ol 5.03E-04 2.10E-04 

3.00E-Ol 7.00E-04 1.06E-03 

4.00E-Ol 8. 58E-04 3.07E-03 

5.00E-Ol 9.85E-04 6. 67E-03 

6.00E-Ol 1.09E-03 1.21E-02 

7.00E-Ol 1. 17E-03 1. 94E-02 

8.00E-Ol I.24E-03 2. 86E-02 

9.00E-Ol I.29E-03 3. 96E-02 

1.00E+OO 1. 34E-03 1.34E-03 5. 21E-02 5. 21E-02 

2.00E+OO I.69E-04 I.50E-03 1.61E-Ol 2.l3E-Ol 

3.00E+OO 2. 95E-05 1. 53E-03 1.31E-Ol 3.44E-Ol 

4.00E+OO 1. 19E-05 1.55E-OJ 7.36E-02 4. 17E-Ol 

5.00E+OO 9.11E-06 1. 55E-03 3.64E-02 4.54E-Ol 

6.00E+OO 8. 42E-06 1.56E-03 1.73E-02 4.7IE-Ol 

7.00E+OO 8. 14E-06 1. 57E-03 8.l3E-03 4. 79E-Ol 

8.00E+OO 7. 99E-06 1.58E-03 3.88E-03 4.83E-Ol 

9.00E+OO 7.90E-06 1. 59E-03 1.91E-03 4. 85E-01 

1.00E+Ol 7. 83E-06 1.59E-03 9. 85E-04 4.86E-OI 

2.00E+Ol 7. 51E-06 1.67E-03 1.36E-04 4. 88E-OI 

3.00E+Ol 7.39E-06 1.75E-03 1.33E-04 4. 89E-Ol 

4.00E+01 7. 35E-06 I.82E-03 I.3IE-04 4.9IE-OI 

5.00E+OI 7. 36E-06 I. 89E-03 I.29E-04 4. 92E-Ol 

7.00E+Ol 7.42E-06 2.04E-03 1. 26E-04 4. 95E-OI 

8.00E+OI 7. 45E-06 2.llE-03 I.24E-04 4. 96E-OI 

9.00E+Ol 7.49E-06 2.19E-03 1.22E-04 4. 97E-OI 

I.OOE+02 7. 53E-06 2. 26E-03 1.21E-04 4. 98E-Ol 

2.00E+02 7. 89E-06 3.04E-03 I.05E-04 5.lOE-OI 

3.00E+02 8. 16E-06 3.84E-03 9. 14E-05 5.19E-OI 

4.00E+02 8. 35E-06 4.67E-03 7. 96E-05 5.28E-Ol 

5.00E+02 8. 48E-06 5.51E-03 6. 93E-05 5. 35E-Ol 

7.00E+02 8. 58E-06 7.22E-03 5. 25E-05 5.47E-Ol 

8.00E+02 8. 57E-06 8.07E-03 4.57E-05 5. 52E-Ol 

9.00E+02 8. 53E-06 8. 93E-03 3. 98E-05 5. 57E-Ol 

1.00E+03 8. 46E-06 9. 78E-03 3.47E-05 5.60E-Ol 

2.00E+03 7.11E-06 1. 76E-02 8. 66E-06 5.79E-Ol 

3.00E+03 5. 63E-06 2.40E-02 2.17E-06 5. 84E-OI 

4.00E+03 4.44E-06 2.90E-02 5.41E-07 5. 85E-OI 

5.00E+03 3. 54E-06 3.30E-02 1.35E-07 5.85E-Ol 

7.00E+03 2. 31E-06 3. 87E-02 O.OOE+OO 5. 85E-Ol 

8.00E+03 I.88E-06 4.08E-02 O.OOE+OO 5. 85E-Ol 

9.00E+03 1. 53E-06 4. 25E-02 O.OOE+OO 5. 85E-Ol 

1.00E+04 1. 25E-06 4. 39E-02 O.OOE+OO 5.85E-Ol 

2.00E+04 1.72E-07 4. 93E-02 O.OOE+OO 5. 85E-Ol 

B-426 
CLASS Y AKAD = 1 MICRON STABLE TANTALUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.B9E-03 3.04E-Ol 2.SBE-Ol 7.30E-02 6.39E-01 

2.00E-Ol 3.90E-03 2.BSE-Ol 2.l7E-Ol 1.33E-Ol 6. 39E-Ol 

3.00E-Ol 3. 92E-03 2.70E-Ol 1. B2E-Ol 1. B2E-Ol 6.3BE-Ol 

4.00E-Ol 3.94E-03 2.S7E-Ol 1.S3E-Ol 2.2lE-Ol 6.36E-Ol 

5.00E-Ol 3.96E-03 2.47E-Ol 1.29E-Ol 2. S2E-01 6.32E-Ol 

6.00E-Ol 3.9BE-03 2.3BE-Ol 1.0BE-Ol 2. 76E-Ol 6. 27E-Ol 

7.00E-Ol 3.99E-03 2.3lE-Ol 9. 12E-02 2. 93E-Ol 6.20E-Ol 

B.OOE-Ol 4.00E-03 2. 24E-Ol 7. 67E-02 3.0SE-Ol 6.lOE-Ol 

9.00E-Ol 4.00E-03 2.l9E-0l 6.4SE-02 3.l2E-0l S.99E-01 

1.OOE+OO 4.00E-03 2.l3E-Ol 5.42E-02 3.lSE-Ol S.B7E-Ol 

2.00E+OO 3.90E-03 1. BOE-Ol 9.S9E-03 2. 32E-Ol 4. 26E-01 

3.00E+OO 3.7SE-03 1.6SE-Ol 1.70E-03 1.2SE-Ol 2.9SE-01 

4.00E+OO 3.6lE-03 1. S7E-0l 3.00E-04 6.07E-02 2.2lE-Ol 

S.OOE+OO 3. 49E-03 1.S3E-Ol S.30E-OS 2. BSE-02 1. BSE-Ol 

6.00E+OO 3.3BE-03 1. SlE-Ol 9. 37E-06 1. 34E-02 1. 67E-Ol 

7.00E+OO 3. 29E-03 1.49E-Ol 1.66E-06 6. 43E-03 1. S9E-Ol 

B.OOE+OO 3. 21E-03 1.49E-Ol 2. 93E-07 3.lBE-03 1. SSE-Ol 

9.00E+OO 3.l4E-03 1.4BE-OI S.17E-OB 1. 65E-03 1.S3E-OI 

1.00E+Ol 3.0BE-03 1.48E-Ol O.OOE+OO 9.20E-04 1.S2E-Ol 

2.00E+01 2. 78E-03 1.46E-OI O.OOE+OO 2.36E-04 1.49E-Ol 

3.00E+Ol 2. 67E-03 1.4SE-Ol O.OOE+OO 2. 32E-04 1.4BE-Ol 

4.00E+Ol 2.60E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.46E-Ol 

S.OOE+Ol 2.S4E-03 1.42E-OI O.OOE+OO 2. 26E-04 1.4SE-Ol 

6.00E+Ol 2.4BE-03 1.4lE-Ol O.OOE+OO 2. 23E-04 1. 43E-Ol 

7.00E+Ol 2.43E-03 1. 39E-Ol O.OOE+OO 2.20E-04 1.42E-Ol 

8.00E+Ol 2. 38E-03 1. 38E-01 O.OOE+OO 2. 17E-04 1.40E-Ol 

9.00E+Ol 2. 34E-03 1.36E-OI O.OOE+OO 2.l4E-04 1. 39E-Ol 

1.OOE+02 2.30E-03 1.3SE-Ol O.OOE+OO 2.l1E-04 1.37E-Ol 

2.00E+02 2.03E-03 1.22E-0l O.OOE+OO 1. B3E-04 1. 24E-Ol 

3.00E+02 1.90E-03 1.lOE-Ol O.OOE+OO 1.60E-04 1.12E-Ol 

4.00E+02 1.B4E-03 9.9BE-02 O.OOE+OO 1.39E-04 1.02E-Ol 

S.OOE+02 1.80E-03 9.06E-02 O.OOE+OO 1.2lE-04 9.2SE-02 

6.00E+02 1.77E-03 B.23E-02 O.OOE+OO 1.0SE-04 B.42E-02 

7.00E+02 1. 74E-03 7. 49E-02 O.OOE+OO 9.17E-OS 7.67E-02 

B.OOE+02 1.70E-03 6.B3E-02 O.OOE+OO 7.9BE-OS 7.0lE-02 

9.00E+02 1. 66E-03 6. 23E-02 O.OOE+OO 6.9SE-OS 6.4lE-02 , '. 1.OOE+03 1.6lE-03 S.70E-02 O.OOE+OO 6.0SE-OS S.B7E-02 

2.00E+03 1.02E-03 2.SSE-02 O.OOE+OO 1.SIE-OS 2.6SE-02 

3.00E+03 S.6SE-04 1. 34E-02 O.OOE+OO 3. 78E-06 1.39E-02 

4.00E+03 2. 96E-04 B.2SE-03 ·O.OOE+OO 9. 46E-07 B.SSE-03 

S.OOE+03 1.5lE-04 S.92E-03 O.OOE+OO 2. 36E-07 6.07E-03 

6.00E+03 7.66E-OS 4. BlE-03 O.OOE+OO S.91E-OB 4.B8E-03 

7.00E+03 3. BSE-OS 4.27E-03 O.OOE+OO 1.4BE-OB 4.3lE-03 

8.00E+03 1. 93E-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.02E-03 

9.00E+03 9. 66E-06 3.87E-03 O.OOE+OO O.OOE+OO 3.BBE-03 

1.00E+04 4.B3E-06 3.80E-03 O.OOE+OO O.OOE+OO 3.8lE-03 

B-427 
CLASS Y AMAD- 1 MICRON STABLE TANTALUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.l6E-OS 1.04E-OS 

2.00E-Ol 4. 66E-OS 2:lOE-04 

3.00E-Ol 7.lSE-OS i.06E-03 

4.00E-Ol 9. 63E-OS 3.07E-03 

S.OOE-Ol 1.2lE-04 6. 66E-03 

6.00E-Ol 1. 46E-04 1.2lE-02 

7.00E-Ol 1.70E-04 1.94E-02 

8.00E-Ol 1. 94E-04 2. 86E-02 

9.00E-Ol 2.l8E-04 3. 96E-02 

1.OOE+OO 2.42E-04 2. 42E-04 S.2lE-02 S.2lE-02 

2.00E+OO 2. 24E-04 4.66E-04 1.6IE-0l 2.l3E-Ol 

3.00E+OO I.96E-04 6. 62E-04 I.3IE-Ol 3. 43E-Ol 

4.00E+OO 1.70E-04 8.32E-04 7. 36E-02 4.17E-Ol 

S.OOE+OO I.47E-04 9.80E-04 3. 64E-02 4.S3E-OI 

6.00E+OO 1. 28E-04 I.lIE-03 1.72E-02 4.71E-OI 

7.00E+OO 1.12E-04 1. 22E-03 8.12E-03 4. 79E-Ol 

8.00E+OO 9.8IE-OS I.32E-03 3.88E-03 4. 83E-Ol 

9.00E+OO 8.6SE-OS I.40E-03 1.9IE-03 4.8SE-Ol 

1.OOE+Ol 7.68E-OS 1.48E-03 9.8SE-04 4. 86E-Ol 

2.00E+Ol 3. 39E-OS 1. 96E-03 I.3SE-04 4. 88E-Ol 

3.00E+OI 2.60E-OS 2. 24E-03 I.33E-04 4.89E-OI 

4.00E+Ol 2. 42E-OS 2. 49E-03 I.3IE-04 4.90E-OI 

S.OOE+Ol 2. 36E-OS 2.73E-03 I.29E-04 4.92E-Ol 

6.00E+Ol 2. 32E-OS 2. 96E-03 1. 27E-04 4. 93E-OI 

7.00E+Ol 2. 29E-OS 3.l9E-03 1.26E-04 4. 94E-Ol 

8.00E+OI 2.2SE-OS 3. 42E-03 1. 24E-04 4.9SE-Ol 

9.00E+Ol 2. 23E-OS 3. 64E-03 1.22E-04 4.97E-Ol 

1.OOE+02 2.20E-OS 3. 86E-03 1.2IE-04 4. 98E-Ol 

2.00E+02 2.02E-OS S.96E-03 1.OSE-04 S.09E-Ol 

3.00E+02 1.94E-OS 7. 94E-03 9.l4E-OS S.19E-Ol 

4.00E+02 I.90E-OS 9.86E-03 7. 96E-OS S.27E-Ol 

S.OOE+02 1.87E-OS 1.l7E-02 6. 93E-OS S.3SE-Ol 

7.00E+02 1.80E-OS I.S4E-02 S.2SE-OS S.47E-Ol 

8.00E+02 l.76E-OS 1.72E-02 4.S7E-OS S.S2E-Ol 

9.00E+02 I.71E-OS 1.89E-02 3. 98E-OS S.S6E-Ol , . 

" I.OOE+03 I.6SE-OS 2.06E-02 3.46E-OS S.60E-Ol 

2.00E+03 1.04E-OS 3.4IE-02 8. 66E-06 S.79E-Ol 

3.00E+03 S.73E-06 4.l9E-02 2. 16E-06 S.83E-Ol 

4.00E+03 3.00E-06 4. 62E-02 S.4IE-07 S.84E-Ol 

S.OOE+03 I.S3E-06 4. 83E-02 1.3SE-07 S.8SE:-Ol 

7.00E+03 3. 89E-07 S.OOE-02 O.OOE+OO S.8SE-Ol 

8.00E+OJ I.9SE-07 S.03E-02 O.OOE+OO S.8SE-Ol 

9.00E+03 9. 77E-08 S.04E-02 O.OOE+OO S.8SE-Ol 

1.00E+04 4. 89E-08 S.OSE-02 O.OOE+OO S.8SE-OI 

B-428 
CLASS Y AMAD = 1 MICRON BALFLIFE= 1.1.5E+02 DAYS TANTALUM. 182 

. !I .... 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-Ol 3. 88E-03 3.04E-Ol 2. S8E-0l 7.30E-02 6. 39E-Ol 

2.00E-Ol 3.89E-03 2.8SE-OI 2.17E-Ol 1.33E-Ol 6.3SE-OI 

3.00E-0l 3.9lE-03 2. 69E-OI 1.82E-0l 1. SlE-OI 6. 37E-Ol 

4.00E-Ol 3. 93E-03 2.S7E-Ol I.S3E-OI 2.2lE-Ol 6. 34E-OI 

S.OOE-Ol 3.9SE-03 2.46E-OI I.29E-Ol 2. SlE-Ol 6.30E-Ol 

6.00E-Ol 3. 96E-03 2.38E-Ol 1.08E-OI 2.7SE-Ol 6.2SE-Ol 

7.00E-OI 3. 97E-03 2.30E-OI 9.09E-02 2.92E-Ol 6.17E-Ol 

8.00E-Ol 3. 98E-03 2. 23E-Ol 7.64E-02 3.04E-Ol 6.07E-OI 

9.00E-Ol 3.9SE-03 2.17E-0l 6. 42E-02 3. llE-Ol S.96E-Ol 

1.OOE+OO 3. 98E-03 2.l2E-Ol S.39E-02 3.13E-Ol S.83E-Ol 

2.00E+OO 3.S6E-03 1.78E-Ol 9. 47E-03 2. 29E-Ol 4.2IE-Ol 

3.00E+OO 3. 69E-03 1. 62E-OI 1. 66E-03 1. 23E-Ol 2.90E-Ol 

4.00E+OO 3. 53E-03 1. 53E-Ol 2.93E-04 S.92E-02 2.l6E-Ol 

S.OOE+OO 3. 38E-03 I.4SE-OI 5.14E-OS 2.77E-02 1. 79E-Ol 

6.00E+OO 3. 26E-03 1.4SE-OI 9.03E-06 I.30E-02 1.6lE-0l 

7.00E+OO 3.l5E-03 1. 43E-Ol 1.S9E-06 6.17E-03 1. 53E-Ol 

8.00E+OO 3.06E-03 I.42E-Ol 2.79E-07 3.03E-03. I.48E-Ol 

9.00E+OO 2.97E-03 1.4IE-OI 4~90E-OS 1.S6E-03 1.4SE-Ol 

I.OOE+OI 2.90E-03 1.39E-0l O.OOE+OO 8. 66E-04 1.43E-Ol 

2.00E+Ol 2. 46E-03 1.30E-OI O.OOE+OO 2.09E-04 1. 32E-OI 

3.00E+Ol 2.23E-03 1.2lE-OI O.OOE+OO 1. 94E-04 1.23E-Ol 

4.00E+Ol 2.04E-03 1.l3E-OI O.OOE+OO 1.SOE-04 1.lSE-Ol 

S.OOE+OI 1. 88E-03 1.OSE-0l O.OOE+OO I.67E-04 1.07E-Ol 

6.00E+Ol 1. 73E-03 9. 79E-02 O.OOE+OO 1.SSE-04 9.98E-02 

7.00E+OI 1.S9E-03 9.12E-02 O.OOE+OO I.44E-04 9. 29E-02 

8.00E+Ol I.47E-03 8.S0E-02 O.OOE+OO 1. 34E-04 8. 66E-02 

9.00E+Ol 1. 36E-03 7.92E-02 O.OOE+OO I.24E-04 8.07E-02 

1.OOE+02 I.26E-03 7. 38E-02 O.OOE+OO 1.15E-04 7.S2E-02 

2.00E+02 6.07E-04 3.6SE-02 O.OOE+OO S.SOE-OS 3.71E-02 

3.00E+02 3.12E-04 I.8IE-02 O.OOE+OO 2. 62E-OS 1. 84E-02 

4.00E+02 1.6SE-04 S.96E-03 O.OOE+OO I.2SE-OS 9.l3E-03 

S.OOE+02 8. 86E-OS 4.4SE-03 O.OOE+OO 5. 94E-06 4.S4E-03 

6.00E+02 4. 77E-OS 2.2IE-03 O.OOE+OO 2. 83E-06 2.26E-03 

7.00E+02 2. 56E-OS I.lOE-03 O.OOE+OO 1.3SE-06 I.l3E-03 

8.00E+02 1. 37E-OS 5.50E-04 O.OOE+OO 6.43E-07 5. 64E-04 

9.00E+02 7.30E-06 2.7SE-04 O.OOE+OO 3.06E-07 2. 82E-04 

,,' ." .. ' I.OOE+03 3. 88E-06 1. 37E-04 O.OOE+OO 1. 46E-07 I.42E-04 

B-429 
CLASS Y AMAD = 1 MICRON HALFLlFE= 1.15£+02 DAYS TANTALUM 182 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 16E-05 1.04E-05 

2.00E-Ol 4. 66E-05 2.1OE-04 ... 3.00E-Ol 7. 14E-05 1.06E-03 

4.00E-Ol 9.61E-05 3.06E-03 

5.00E-Ol 1.21E-04 6. 64E-03 

6.00E-Ol 1. 45E-04 1.20E-02 

7.00E-Ol 1.69E-04 1. 93E-02 

8.00E-Ol 1. 93E-04 2. 85E-02 

9.00E-Ol 2. 17E-04 3. 94E-02 

1.00E+00 2.41E-04 2. 41E-04 5. 17E-02 5. 17E-02 

2.00E+00 2. 21E-04 4. 61E-04 1.59E-01 2.10E-Ol 

3.00E+00 1. 92E-04 6. 51E-04 1. 28E-Ol 3. 37E-Ol 

4.00E+00 1. 66E-04 8.13E-04 7.18E-02 4.07E-Ol 

5.00E+00 1. 43E-04 9. 51E-04 3. 53E-02 4.40E-Ol 

6.00E+00 1. 24E-04 1.07E-03 1.66E-02 4. 54E-Ol 

7.00E+00 1.07E-04 1. 17E-03 7. 78E-03 4. 59E-01 

8.00E+00 9. 35E-05 1.26E-03 3.70E-03 4.60E-Ol 

9.00E+00 8.20E-05 1. 33E-03 1.81E-03 4. 59E-01 

1.00E+Ol 7.23E-05 1.39E-03 9.27E-04 4. 57E-Ol 

2.00E+Ol 3.01E-05 1.73E-03 1.20E-04 4. 32E-Ol 

3.00E+01 2. 17E-05 1.87E-03 1. 11E-04 4.08E-Ol 

4.00E+Ol 1.90E-05 1. 96E-03 1.03E-04 3. 85E-Ol 

5.00E+Ol 1. 75E-05 2.02E-03 9. 56E-05 3. 64E-Ol 

6.00E+Ol 1. 62E-05 2.06E-03 8. 88E-05 3. 43E-01 

7.00E+Ol 1.50E-05 2.09E-03 8. 24E-05 3. 24E...,01 

8.00E+Ol 1. 39E-05 2. 11E-03 7. 65E-05 3.06E-Ol 

9.00E+Ol 1. 29E-05 2.12E-03 7.11E-05 2.89E-Ol 

1.00E+02 1.20E-05 2.llE-03 6.60E-05 2. 73E-Ol 

2.00E+02 6.06E-06 1. 79E-03 3. 14E-05 1.53E-Ol 

3.00E+02 3. 19E-06 1.30E-03 1.50E-05 8.51E-02 

4.00E+02 1.70E-06 8.85E-04 7.14E-06 4. 73E-02 

5.00E+02 9. 17E-07 5.77E-04 3.40E-06 2. 63E-02 

6.00E+02 4. 94E-07 3~65E-04 1. 62E-06 1.46E-02 

7.00E+02 2. 65E-07 2. 27E-04 7.72E-07 8.05E-03 

8.00E+02 1.41E-07 1.38E-04 3.68E-07 4. 44E-03 

9.00E+02 7. 52E-08 8. 34E-05 1. 75E-07 2. 45E-03 

1.00E+03 3. 99E-08 4. 97E-05 8.35E-08 1.35E-03 

B-430 
CLASS Y AMAD "" 1 MICRON STABLE OSMIUM 190 

TI~E AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.S2E-03 3.04E-Ol 2.SSE-Ol 7.30E-02 6.39E-Ol 

2.00E~Ol 3. 99E-03 2. BSE-Ol 2.l7E-Ol 1.33E-Ol 6.39E-Ol 

3.00E-Ol 4.2SE-03 2.70E-Ol 1.S2E-Ol 1. SlE-Ol 6.3BE-Ol 

4.00E-Ol 4.6lE-03 2.S7E-Ol 1.S3E-Ol 2.20E-Ol 6.3SE-Ol 

S.OOE-OI 4. 92E-03 2.47E-Ol 1.29E-Ol 2. SlE-01 6.32E-01 

6.00E-Ol S.I9E-03 2. 38E-OI 1.OBE-Ol 2.74E-01 6.26E-01 

7.00E-01 S.43E-03 2.31E-01 9.l2E-02 2.9lE-Ol 6. 19E-Ol 

8.00E-01 S.62E-03 2. 24E-01 7.67E-02 3.03E-Ol 6.10E-01 

9.00E-01 S.79E-03 2.l9E-Ol 6.4SE-02 3.10E-0l S.99E-01 

1.OOE+OO S.92E-03 2.I3E-Ol S.42E-02 3. 13E-OI S.B6E-OI 

2.00E+OO 6.S0E-03 1. SOE-Ol 9.S9E-03 2.30E-Ol 4.26E-OI 

3.00E+OO 6.S9E-03 I.6SE-Ol 1.70E-03 1.24E-Ol 2.97E-01 

4.00E+OO 6. S7E-03 1.S7E-01 3.00E-04 6.00E-02 2.24E-Ol 

S.OOE+OO 6.S1E-03 1. S3E-01 S.30E-OS 2.B3E-02 I.B7E-Ol 

6.00E+OO 6. 44E-03 1.SlE-01 9. 37E-06 1. 33E-02 1.70E-Ol 

7.00E+OO 6. 37E-03 1.49E-Ol 1. 66E-06 6.37E-03 1. 62E-Ol 

B.OOE+OO 6.3lE-03 1.49E-Ol 2. 93E-07 3.14E-03 1.SBE-Ol 

9.00E+OO 6.24E-03 1.4BE-Ol S.17E-OB 1. 63E-03 1.S6E-01 

1.00E+01 6.lBE-03 1.4BE-Ol O.OOE+OO 9.11E-04 1.SSE-Ol 

2.00E+Ol S.76E-03 1.46E-Ol O.OOE+OO 2. 34E-04 1.S2E-Ol 

3.00E+01 S.SSE-03 1.4SE-01 O.OOE+OO 2.30E-04 1.SlE-Ol 

4.00E+01 S.42E-03 I.43E-01 O.OOE+OO 2.27E-04 1.49E-Ol 

S.OOE+01 S.33E-03 1.42E-Ol O.OOE+OO 2.24E-04 1.4SE-Ol 

6.00E+Ol S.26E-03 1.4lE-Ol O.OOE+OO 2. 21E-04 1.46E-01 

7.00E+01 S.20E-03 1.39E-Ol O.OOE+OO 2.lBE-04 1.44E-Ol 

B.OOE+01 S.14E-03 1.3BE-Ol O.OOE+OO 2.lSE-04 1.43E-Ol 

9.00E+Ol S.OSE-03 1.36E-Ol O.OOE+OO 2.l2E-04 1.42E-Ol 

1.OOE+02 S.03E-03 1.3SE-Ol O.OOE+OO 2.09E-04 1.40E-Ol 

2.00E+02 4.61E-03 1.22E-Ol O.OOE+OO 1. B2E-04 1.27E-Ol 

3.00E+02 4. 32E-03 1. lOE-Ol O.OOE+OO 1.SBE-04 1.lSE-Ol 

4.00E+02 4.llE-03 9.9BE-02 O.OOE+OO 1.3BE-04 1.04E-Ol 

S.OOE+02 3.9SE-03 9.06E-02 O.OOE+OO 1.20E-04 9.46E-02 

6.00E+02 3.B2E-03 B.23E-02 O.OOE+OO 1.04E-04 S.62E-02 

7.00E+02 3.70E-03 7.49E-02 O.OOE+OO 9.09E-OS 7.S7E-02 

B.OOE+02 3.S9E-03 6.B3E-02 O.OOE+OO 7.9lE-OS 7.l9E-02 

9.00E+02 3.4BE-03 6. 23E-02 O.OOE+OO 6.B9E-OS 6.S9E-02 ; 1.OOE+03 3. 37E-03 S.70E-02 O.OOE+OO 6.00E-OS 6.04E-02 .' 

2.00E+03 2.lSE-03 2.SSE-02 O.OOE+OO 1.SOE-OS 2.77E-02 

3.00E+03 1. 22E-03 1.34E-02 O.OOE+OO 3.7SE-06 1.46E-02 

4.00E+03 6.4SE-04 S.2SE-03 O.OOE+OO 9.37E-07 8.B9E-03 

S.OOE+03 3.3lE-04 S.92E-03 O.OOE+OO 2. 34E-07 6.2SE-03 

7.00E+03 B.43E-OS 4. 27E-03 O.OOE+OO 1. 46E-OB 4. 35E-03 

B.OOE+03 4.23E-OS 4.00E-03 O.OOE+OO O.OOE+OO 4.04E-03 

9.00E+03 2.12E-OS 3.B7E-03 O.OOE+OO O.OOE+OO 3.B9E-03 

1.OOE+04 1.06E-OS 3. BOE-03 O.OOE+OO O.OOE+OO ' 3. BlE-03 

2.00E+04 1.04E-OB 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-43l 
CLASS Y AMAD = 1 MICRON STABLE OSMIUM 190 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----~-------------~---- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.7lE-04 1.04E-OS 

2.00E-Ol 3. 38E-04 2.l0E-04 

3.00E-Ol 4. 87E-04 1.OSE-03 

4.00E-Ol 6. 24E-04 3.06E-03 

S.OOE-Ol 7.S2E-04 6. 64E-03 

6.00E-Ol 8. 73E-04 1.20E-02 

7.00E-Ol 9. 84E-04 1. 93E-02 

8.00E-Ol 1.09E-03 2.8SE-02 

9.00E-Ol 1.18E-03 3. 93E-02 

1.OOE+OO 1. 27E-03 1. 27E-03 S.17E-02 S.17E-02 

2.00E+OO S.20E-04 1. 79E-03 1.S9E-Ol 2.llE-Ol 

3.00E+OO 2.30E-04 2.02E-03 1.30E-Ol 3.4lE-Ol 

4.00E+OO 1.SlE-04 2.17E-03 7. 28E-02 4.l3E-Ol 

S.OOE+OO 1. 23E-04 2. 29E-03 3.60E-02 4.49E-Ol 

6.00E+OO 1.09E-04 2.40E-03 1.7lE-02 4. 66E-Ol 

7.00E+OO 9. 98E-OS 2.S0E-03 8.04E-03 4. 74E-Ol 

8.00E+OO 9.2SE-OS 2.S9E-03 3. 84E-03 4. 78E-Ol 

9.00E+OO 8. 64E-OS 2. 68E-03 1.89E-03 4.80E-Ol 

1.OOE+01 8.lOE-OS 2. 76E-03 9.7SE-04 4.8IE-Ol 

2.00E+Ol 4. 87E-OS 3. 37E-03 1.34E-04 4.83E-Ol 

3.00E+Ol 3.S2E-OS 3.77E-03 1. 32E-04 4.8SE-Ol 

4.00E+Ol 2. 94E-OS 4.09E-03 1.30E-04 4. 86E-Ol 

S.OOE+Ol 2. 68E-OS 4. 37E-03 1. 28E-04 4.87E-Ol 

6.00E+Ol 2.S6E-OS 4. 63E-03 1. 26E-04 4. 88E-Ol 

7.00E+Ol 2.S0E-OS 4. 88E-03 1.2SE-04 4.90E-Ol 

8.00E+Ol 2. 47E-OS S.13E-03 1. 23E-04 4.91E-Ol 

9.00E+Ol 2. 44E-OS S.37E-03 1.21E-04 4. 92E-Ol 

1.OOE+02 2. 42E-OS S.62E-03 1.19E-04 4.93E-Ol 

2.00E+02 2. 28E-OS 7. 96E-03 1.04E-04 S.OSE-Ol 

3.00E+02 2.18E-OS 1.02E-02 9.06E-OS S.14E-Ol 

4.00E+02 2.llE-OS 1. 23E-02 7. 88E-OS S.23E-Ol 

S.OOE+02 2.04E-OS 1.44E-02 6. 86E-OS S.30E-Ol 

7.00E+02 1. 92E-OS 1. 84E-02 S.20E-OS S.42E-Ol 

8.00E+02 1. 87E-OS 2.03E-02 4.S3E-OS S.47E-Ol 

9.00E+02 1.81E-OS 2.2lE-02 3. 94E-OS S.SlE-Ol .,' 

1.OOE+03 1.7SE-OS 2. 39E-02 3. 43E-OS S.SSE-Ol 

2.00E+03 1.llE-OS 3.8lE-02 8.S8E-06 S.73E-Ol 

3.00E+03 6.1SE-06 4.6SE-02 2.l4E-06 S.78E-Ol 

4.00E+03 3. 23E-06 S.11E-02 S.36E-07 S.79E-Ol 

S.OOE+03 1.6SE-06 S.34E-02 1. 34E-07 S.79E-Ol 

7.00E+03 4.2lE-07 S.S2E-02 O.OOE+OO S.80E-Ol 

8.00E+03 2.llE-07 S.SSE-02 O.OOE+OO S.80E-Ol 

9.00E+03 1.06E-07 S.S7E-02 O.OOE+OO S.80E-Ol 

l.OOE+04 S.29E-08 S.S8E-02 O.OOE+OO S.80E-Ol 

B-432 
CLASS Y AHA» = 1 KICRON HALFLIFE= 7. 40E+O 1 DAYS IRIDIUM 192 

TI~1E AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------------~-- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.0OE-01 3.82E-03 3.04E-Ol 2. S8E-Ol 7.29E-02 6. 38E-Ol 

2.00E-Ol 3. 98E-03 2.8SE-Ol 2.I7E-OI I.32E-Ol 6.37E-OI 

3.00E-Ol 4.27E-03 2. 69E-Ol I.82E-Ol 1.80E-Ol 6.36E-Ol 

4.00E-OI 4.S9E-03 2. 56E-Ol I.S3E-OI 2.19E-OI 6.33E-OI 

S.OOE-OI 4.89E-03 2.46E-OI I.28E-OI 2.49E-OI 6. 29E-OI 

6.00E-OI S.I6E-03 2.37E-OI 1.08E-OI 2. 73E-OI 6. 23E-Ol 

7.00E-OI S.39E-03 2.29E-OI 9.06E-02 2.89E-OI 6. ISE-OI 

8.00E-Ol S.S8E-03 2. 23E-Ol 7.6IE-02 3.0IE-OI 6.0SE-Ol 

9.00E-OI S.74E-03 2.l7E-0l 6.40E-02 3.07E-OI S.94E-OI 

I.OOE+OO S.87E-03 2.11E-OI S.37E-02 3. WE-OI S.8IE-OI 

2.00E+00 6.38E-03 I.77E-OI 9.4IE-03 2.26E-OI 4.18E-OI 

3.00E+OO 6.4IE-03 I.60E-OI 1.6SE-03 I.20E-Ol 2. 88E-OI 

4.00E+OO 6. 33E-03 1. SIE-OI 2.89E-04 S.78E-02 2. ISE-OI 

S.OOE+OO 6.2IE-03 I.46E-Ol S.06E-OS 2.70E-02 I.79E-Ol 

6.00E+OO 6.09E-03 I.42E-OI 8.8SE-06 I.26E-02 1.6IE-OI 

7.00E+OO S.97E-03 l.40E-Ol I.SSE-06 S.96E-03 1.S2E-OI 

8.00E+OO S.8SE-03 I.38E-OI 2.72E-07 2. 92E-03 1.47E-OI 

9.00E+OO S.74E-03 l.36E-01 4. 76E-08 I.SOE-03 l.44E-OI 

I.OOE+Ol S.63E-03 l.3SE-Ol O.OOE+OO 8.29E-04 I.41E-OI 

2.00E+OI 4. 78E-03 I.2IE-Ol O.OOE+OO 1. 94E-04 1. 26E-OI 

3.00E+Ol 4.l9E-03 I.09E-Ol O.OOE+OO 1. 74E-04 1.14E-OI 

4.00E+OI 3.73E-03 9.86E-02 O.OOE+OO I.S6E-04 1.03E-01 

S.OOE+Ol 3. 34E-03 8. 89E-02 O.OOE+OO I.40E-04 9. 24E-02 

6.00E+OI 3.00E-03 8.0IE-02 O.OOE+OO 1. 26E-04 8.32E-02 

7.00E+OI 2.70E-03 7. 22E-02 O.OOE+OO 1.13£-04 7. SOE-02 

8.00E+Ol 2.43E-03 6.S1E-02 O.OOE+OO 1.02E-04 6. 76E-02 

9.00E+OI 2.19E-03 S.87E-02 O.OOE+OO 9.12E-OS 6.09E-02 

I.OOE+02 l.97E-03 5. 29E-02 O.OOE+OO 8.I9E-OS S.49E-02 

2.00E+02 7.09E-04 I.87E-02 O.OOE+OO 2. 79E-OS I.95E-02 

3.00E+02 2.60E-04 6. 64E-03 O.OOE+OO 9.S4E-06 6.9IE-03 

4.00E+02 9. 72E-OS 2. 36E-03 O.OOE+OO 3.2SE-06 2. 46E-03 

S.OOE+02 3. 66E-OS 8. 39E-04 O.OOE+OO 1.IIE-06 8. 76E-04 

6.00E+02 I.39E-OS 2.99E-04 O.OOE+OO 3.79E-07 3.I3E-04 

7.00E+02 S.27E-06 I.07E-04 O.OOE+OO 1. 29E-07 1.I2E-04 

8.00E+02 2.00E-06 3.8lE-OS O.OOE+OO 4.4IE-08 4.0IE-OS ' .. ' 9.00E+02 7.6lE-07 1.36E-OS O.OOE+OO 1.SlE-08 1. 44E-OS .. 

1.00E+03 2. 89E-07 4. 89E-06 O.OOE+OO O.OOE+OO S.18E-06 

B-433 
CLASS Y AHAD= 1 MICRON HALFLIFE= 7. 40E+Ol DAYS IRIDIUM 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.71E-04 1.04E-05 

2.00E-Ol 3. 38E-04 2.09E-04 

3.00E-Ol 4.86E-04 1.05E-03 

4.ooE-01 6. 22E-04 3.05E-03 

5.00E-Ol 7. 49E-04 6. 61E-03 

6.00E-Ol 8. 68E-04 1.20E-02 

7.00E-Ol 9. 78E-04 1.92E-02 

8.00E-Ol 1.08E-03 2. 83E-02 

9.00E-Ol 1.17E-03 3.90E-02 

1.00E+00 1. 26E-03 1. 26E-03 5. 13E-02 5. 13E-02 

2.00E+00 5.1OE-04 1. 75E-03 1.56E-Ol 2.07E-Ol 

3.00E+00 2. 24E-04 1. 96E-03 1. 26E-Ol 3. 31E-Ol 

4.00E+00 1.45E-04 2.09E-03 7.01E-02 3. 98E-Ol 

5.00£+00 1. 18E-04 2. 19E-03 3. 44E-02 4. 29E-Ol 

6.00E+00 1.03E-04 2.27E-03 1. 61E-02 4.41E-Ol 

7.00E+00 9.35E-05 2. 34E-03 7. 53E-03 4. 44E-Ol 

8.00E+00 8. 58E-05 2.41E-03 3. 56E-03 4.44E-Ol 

9.00E+00 7.94E-05 2. 46E-03 1. 74E-03 4.41E-Ol 

1.00E+Ol 7. 38E-05 2. 51E-03 8. 88E-04 4. 38E-Ol 

2.00E+Ol 4.04E-05 2. 79E-03 1. 11E-04 4.01E-Ol 

3.00E+Ol 2. 66E-05 2. 85E-03 9. 94E-05 3. 66E-Ol 

4.00E+Ol 2.02E-05 2.81E-03 8. 93E-05 3. 34E-Ol 

5.00E+Ol 1. 68E-05 2. 73E-03 8.02E-05 3.05E-Ol 

6.00E+Ol 1.46E-05 2. 64E-03 7.20E-05 2. 79E-Ol 

7.00E+Ol 1.30E-OS 2.S3E-03 6. 47E-OS 2.S4E-Ol 

8.00E+01 1. 17E-OS 2.42E-03 S.81E-OS 2.32E-Ol 

9.00E+Ol 1.05E-05 2. 31E-03 S.22E-05 2.12E-Ol 

1.00E+02 9.50E-06 2.20E-03 4.68E-05 1. 93E-01 

2.00E+02 3. 51E-06 1.22E-03 1.60E-OS 7. 75E-02 

3.00E+02 1. 32E-06 6. 14E-04 S.46E-06 3.10E-02 

4.00E+02 4. 98E-07 2.91E-04 1.86E-06 1.23E-02 

5.00E+02 1. 89E-07 1. 33E-04 6. 35E-07 4. 91E-03 

6.00E+02 7.20E-08 5. 96E-OS 2. 17E-07 1.9SE-03 

7.00E+02 2.74E-08 2. 62E-05 7.40E-08 7.71E-04 

8.00E+02 1.04E-08 1. 13E-05 2.S3E-08 3.0SE-04 

B-434 
CLASS Y AMAD = 1 KICR.ON STABLE IR.IDIUH 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTE}.tIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.S2E-03 3.04E-01 2.sSE-Ol 7.30E-02 6. 39E-Ol 

2.00E-Ol 3. 99E-03 2.SSE-Ol 2.l7E-Ol 1. 33E-Ol 6.39E-OI 

3.00E-01 4.2SE-03 2.70E-OI 1. S2E-Ol 1. SlE-01 6.3SE-OI 

4.00E-01 4.6IE-03 2.S7E-01 1.s3E-Ol 2.20E-Ol 6.3SE-01 

S.OOE-Ol 4. 92E-03 2. 47E-Ol 1.29E-OI 2.S1E-0l 6. 32E-Ol 

6.00E-Ol s.19E-03 2.3SE-Ol 1.OSE-OI 2. 74E-Ol 6.26E-Ol 

7.00E-Ol S.43E-03 2.3lE-OI 9.12E-02 2.9lE-OI 6.l9E-OI 

S.OOE-OI S.62E-03 2. 24E-Ol 7. 67E-02 3.03E-OI 6.lOE-Ol 

9.00E-Ol 5. 79E-03 2.l9E-OI 6.4SE-02 3.lOE-OI S.99E-Ol 

I.OOE+OO 5. 92E-03 2. l3E-Ol s.42E-02 3. l3E-Ol S.S6E-Ol 

2.00E+OO 6.S0E-03 1. SOE-Ol 9.s9E-03 2.30E-Ol 4. 26E-Ol 

3.00E+OO 6.59E-03 1. 65E-Ol 1. lOE-03 1. 24E-Ol 2. 97E-Ol 

4.00E+OO 6.s7E-03 1.S7E-Ol 3.00E-04 6.00E-02 2.24E-Ol 

s.OOE+OO 6.slE-03 l.s3E-Ol S.30E-Os 2.S3E-02 1.S7E-Ol 

6.00E+OO 6. 44E-03 1.SlE-Ol 9. 37E-06 1.33E-02 1.70E-Ol 

7.00E+OO 6. 37E-03 1. 49E-Ol 1.66E-06 6. 37E-03 1. 62E-Ol 

S.OOE+OO 6.3lE-03 1.49E-Ol 2.93E-07 3.14E-03 I.SSE-Ol 

9.00E+OO 6. 24E-03 1.4SE-Ol S.17E-08 1. 63E-03 l.s6E-OI 

1.OOE+Ol 6.lSE-03 1.4SE-Ol O.OOE+OO 9.11E-04 I.SSE-Ol 

2.00E+Ol s.76E-03 1.46E-Ol O.OOE+OO 2. 34E-04 I.S2E-Ol 

3.00E+Ol s.SsE-03 1.4sE-OI O.OOE+OO 2.30E-04 l.slE-Ol 

4.00E+Ol s.42E-03 1.43E-OI O.OOE+OO 2. 27E-04 1. 49E-Ol 

s.OOE+Ol s.33E-03 1.42E-OI O.OOE+OO 2.24E-04 1.4SE-01 

6.00E+01 s.26E-03 1.41E-OI O.OOE+OO 2. 21E-04 1.46E-01 

7.00E+01 S.20E-03 1.39E-OI O.OOE+OO 2.1SE-04 1. 44E-Ol 

S.OOE+Ol 5. 14E-03 1.3SE-OI O.OOE+OO 2.lsE-04 1. 43E-Ol 

9.00E+01 S.OSE-03 1.36E-Ol O.OOE+OO 2.l2E-04 1. 42E-Ol 

1.00E+02 s.03E-03 1.3sE-Ol O.OOE+OO 2.09E-04 1.40E-Ol 

2.00E+02 4.6IE-03 1. 22E-Ol O.OOE+OO 1. S2E-04 1. 27E-Ol 

3.00E+02 4. 32E-03 1.lOE-OI O.OOE+OO I.SSE-04 1.lsE-Ol 

4.00E+02 4.1IE-03 9.9SE-02 O.OOE+OO 1.3SE-04 I.04E-Ol 

5.00E+02 3.9SE-03 9.06E-02 O.OOE+OO 1.20E-04 9. 46E-02 

6.00E+02 3.S2E-03 S.23E-02 O.OOE+OO 1.04E-04 S.62E-02 

7.00E+02 3.70E-03 7. 49E-02 O.OOE+OO 9.09E-Os 7.S7E-02 

S.OOE+02 3.59E-03 6.S3E-02 O.OOE+OO 7.91E-Os 7.l9E-02 

9.00E+02 3.4SE-03 6. 23E-02 O.OOE+OO 6.S9E-OS 6. 59E-02 

1.OOE+03 3. 37E-03 5.70E-02 O.OOE+OO 6.00E-Os 6.04E-02 . 2.00E+03 2.ISE-03 2.SSE-02 O.OOE+OO 1.50E-05 2. 77E-02 

3.00E+03 1.22E-03 1. 34E-02 O.OOE+OO 3.75E-06 I. 46E-02 

4.00E+03 6.4sE-04 S.25E-03 O.OOE+OO 9. 37E-07 S.S9E-03 

S.OOE+03 3.3lE-04 s.92E-03 O.OOE+OO 2.34E-07 6.2SE-03 

7.00E+03 S.43E-Os 4. 27E-03 O.OOE+OO 1.46E-OS 4.3sE-03 

S.OOE+03 4. 23E-05 4.00E-03 O.OOE+OO O.OOE+OO 4.04E-03 

9.00E+03 2.l2E-Os 3.S7E-03 O.OOE+OO O.OOE+OO 3.S9E-03 

1.OOE+04 1.06E-05 3.S0E-03 O.OOE+OO O.OOE+OO 3.SlE-03 

2.00E+04 I.04E-OS 3. 74E-03 O.OOE+OO O.OOE+OO 3. 74E-03 

B-435 
CLASS Y AMAD = 1 KICRON STABLE IRIDIUM 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS' EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.71E-04 I.04E-OS 

2.00E-OI 3. 38E-04 '2. IOE-04 

3.00E-OI 4. 87E-04 I.OSE-03 

.4.00E-OI 6. 24E-04 3.06E-03 

S.OOE-OI 7.S2E-04 6.64E-03 

6.00E-OI 8. 73E-04 1.20E-02 

7.00E-OI 9.84E-04 I.93E-02 

8.00E-OI I.09E-03 2.8SE-02 

9.00E-OI I.18E-03 3. 93E-02 

I.OOE+OO 1. 27E-03 1. 27E-03 S.17E-02 S.I7E-02 

2.00E+OO S.20E-04 I.79E-03 1. S9E-OI 2.11E-OI 

3.00E+OO 2.30E-04 2.02E-03 I.30E-OI 3.4IE-OI 

4.00E+OO 1. SIE-04 2.17E-03 7.28E-02 4.13E-OI 

S.OOE+OO 1. 23E-04 2. 29E-03 3.60E-02 4. 49E-OI 

6.00E+OO I.09E-04 2.40E-03 1.7IE-02 4.66E-OI 

7.00E+OO 9. 98E-OS 2.S0E-03 8.04E-03 4. 74E-OI 

8.00E+OO 9.2SE-OS 2. S9E-03 3. 84E-03 4. 78E-Ol 

9.00E+OO 8.64E-OS 2. 68E-03 1. 89E-03 4.80E-Ol 

1.OOE+Ol 8.lOE-OS 2.76E-03 9.7SE-04 4.8IE-Ol 

2.00E+OI 4. 87E-OS 3. 37E-03 1. 34E-04 4. 83E-OI 

3.00E+OI 3. 52E-OS 3.77E-03 I.32E-04 4.8SE-Ol 

4.00E+Ol 2. 94E-05 4.09E-03 I.30E-04 4. 86E-Ol 

S.OOE+OI 2. 68E-05 4. 37E-03 I.28E-04 4. 87E-OI 

6.00E+Ol 2. 56E-OS 4. 63E-03 1. 26E-04 4. 88E-Ol 

7.00E+OI 2. SOE-OS 4. 88E-03 I.2SE-04 4.90E-Ol 

8.00E+OI 2. 47E-OS 5.l3E-03 1. 23E-04 4.9lE-Ol 

9.00E+OI 2. 44E-05 S.37E-03 I.2IE-04 4. 92E-Ol 

1.OOE+02 2. 42E-OS 5. 62E-03 1.19E-04 4. 93E-Ol 

2.00E+02 2. 28E-OS 7.96E-03 I.04E-04 5.0SE-OI 

3.00E+02 2.l8E-05 I.02E-02 9.06E-OS S.14E-Ol 

4.00E+02 2.11E-05 1. 23E-02 7.88E-OS S.23E-Ol 

S.OOE+02 2.04E-OS 1. 44E-02 6. 86E-OS S.30E-OI 

7.00E+02 1. 92E-OS 1.84E-02 S.20E-OS S.42E-Ol 

8.00E+02 1.87E-OS 2.03E-02 4.S3E-OS S.47E-Ol 

9.00E+02 1.8lE-OS 2.2IE-02 3. 94E-05 S. SlE-OI 

1.OOE+03 I.7SE-OS 2. 39E-02 3. 43E-OS 5.5SE-Ol 

2.00E+03 1.llE-05 3.81E-02 8. 58E-06 S.73E-OI 

3.00E+03 6.15E-06 4. 65E-02 2.14E-06 S.78E-OI 

4.00E+03 3. 23E-06 5.1lE-02 S.36E-07 S.79E-Ol 

5.00E+03 I.6SE-06 5. 34E-02 1. 34E-07 S.79E-Ol 

7.00E+03 4.2IE-07 S.52E-02 O.OOE+OO S.80E-OI 

8.00E+03 2.IIE-07 S. S5E-02 O.OOE+OO 5.80E-Ol 

9.00E+03 1.06E-07 S.S7E-02 O.OOE+OO S.80E-OI 

1.OOE+04 S.29E-08 S.S8E-02 O.OOE+OO S.80E-Ol 

B-436 
CLASS Y AHAD ::: 1 MICRON STABLE GOLD 197 

Tum AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 4. 84E-03 3.04E-01 2.58E-0l 7.20E-02 6. 39E-01 

2.00E-01 8. 17E-03 2. 85E-01 2. 17E-01 1. 28E-01 6. 39E-01 . 3.00E-01 1.2sE-02 2.70E-Ol 1. S2E-0l 1. 73E-Ol 6.3SE-Ol 

4.00E-01 1. 69E-02 2. 57E-01 1.s3E-0l 2.0SE-Ol 6. 35E-01 

s.OOE-Ol 2.09E-02 2.47E-01 1.29E-01 2.34E-0l 6. 32E-01 

6.00E-01 2. 43E-02 2. 38E-01 1.08E-01 2.5sE-Ol 6. 26E-01 

7.00E-01 2.71E-02 2.31E-0l 9. 12E-02 2.69E-01 6.1SE-01 

S.OOE-01 2. 94E-02 2. 24E-01 7.67E-02 2. 79E-Ol 6.09E-01 

9.00E-01 3. 12E-02 2. 19E-01 6.45E-02 2.S4E-01 5. 98E-01 

1.00E+OO 3. 26E-02 2.l3E-Ol 5. 42E-02 2.S6E-01 5.S6E-Ol 

2.00E+OO 3.50E-02 1. SOE-01 9. 59E-03 2.0SE-01 4.33E-01 

3.00E+OO 3.04E-02 1. 65E-01 1.70E-03 1. llE-Ol 3.0SE-01 

4.00E+OO 2.s1E-02 1.s7E-Ol 3.00E-04 s.39E-02 2. 36E-01 

s.OOE+OO 2.04E-02 1.s3E-Ol S.30E-OS 2.S4E-02 1. 98E-01 

6.00E+OO 1. 64E-02 1. SlE-01 9. 37E-06 1. 19E-02 1. 79E-01 

7.00E+OO 1. 32E-02 1. 49E-01 1. 66E-06 s.72E-:-03 1. 68E-01 

S.OOE+OO 1.0SE-02 1. 49E-01 2. 93E-07 2.S3E-03 1. 62E-01 

9.00E+OO S.40E-03 1.4SE-01 S.17E-OS 1. 47E-03 1.SSE-01 

1.00E+01 6.71E-03 1.4SE-0l O.OOE+OO S.21E-04 1. S6E-01 

2r.OOE+01 7.SSE-04 1.46E-01 O.OOE+OO 2.13E-04 1. 47E-01 

3.00E+01 1.9SE-04 1.4SE-01 O.OOE+OO 2.10E-04 1.4SE-01 

4.00E+01 1. 39E-04 1.43E-01 O.OOE+OO 2.07E-04 1.44E-01 

S.OOE+01 1.33E-04 1.42E-Ol O.OOE+OO 2.04E-04 1.42E-Ol 

6.00E+01 1. 32E-04 1.41E-01 O.OOE+OO 2.01E-04 1.41E-01 

7.00E+01 1.31E-04 1.39E-0l O.OOE+OO 1.9SE-04 1.39E-01 

S.OOE+01 1. 31E-04 1.3SE-01 O.OOE+OO 1. 96E-04 1.3SE-01 

9.00E+01 1.31E-04 1.36E-01 O.OOE+OO 1.93E-04 1. 37E-01 

1.00E+02 1.30E-04 1.3SE-01 O.OOE+OO 1.90E-04 1.3SE-01 

2.00E+02 1.2SE-04 1.22E-01 O.OOE+OO 1.66E-04 1.22E-01 

3.00E+02 1.20E-04 1.10E-01 O.OOE+OO 1. 44E-04 1.10E-01 

4.00E+02 1.1SE-04 9.9SE-02 O.OOE+OO 1.26E-04 1.00E-01 

S.OOE+02 1.09E-04 9.06E-02 O.OOE+OO 1.09E-04 9.0SE-02 

6.00E+02 1.04E-04 S.23E-02 O.OOE+OO 9. S2E-Os S.2SE-02 

7.00E+02 9.90E-OS 7.49E-02 O.OOE+OO 8.2SE-Os 7.S1E-02 

S.OOE+02 9.40E-Os 6.83E-02 O.OOE+OO 7. 21E-OS 6.S4E-02 

9.00E+02 S.91E-OS 6. 23E-02 O.OOE+OO 6. 28E-05 6.2SE-02 

1.00E+03 S.43E-OS s.70E-02 O.OOE+OO S.47E-OS S.71E-02 

2.00E+03 4. 64E-OS 2.SSE-02 O.OOE+OO 1. 37E-OS 2.SSE-02 

3.00E+03 2. 43E-OS 1. 34E-02 O.OOE+OO 3. 42E-06 1. 34E-02 

4.00E+03 1. 24E-Os S.2sE-03 O.OOE+OO S.54E-07 S.26E-03 

S.OOE+03 6.26E-06 S.92E-03 O.OOE+OO 2. 14E-07 S.92E-03 

6.00E+03 3.1SE-06 4.S1E-03 O.OOE+OO S.34E-08 4.S1E-03 

7.00E+03 1. SSE-06 4.27E-03 O.OOE+OO 1. 33E-OS 4.27E-03 

S.OOE+03 7.90E-07 4.00E-03 O.OOE+OO O.OOE+OO 4.00E-03 

9.00E+03 3.9SE-07 3.S7E-03 O.OOE+OO O.OOE+OO 3.S7E-03 

1.00E+04 1.9SE-07 3.S0E-03 O.OOE+OO O.OOE+OO 3.S0E-03 

B-437 
CLASS Y AMAD =< 1 MICRON STABLE WLD 197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUHULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol B.32E-05 1.03E-05 

2.00E-Ol 2.30E-04 2.06E-04 

3.00E-Ol 4.6BE-04 1.03E-03 

4.00E-Ol B.09E-04 2. 96E-03 

S.OOE-Ol 1.25E-03 6.37E-03 

6.00E-Ol 1.77E-03 1.15E-02 

7.00E-Ol 2.36E-03 1.B3E-02 

8.00E-Ol 3.02E-03 2. 69E-02 

9.00E-Ol 3.72E-03 3.70E-02 

1.OOE+OO 4. 45E-03 4. 45E-03 4.B5E-02 4. BSE-02 

2.00E+OO 8.09E-03 1.25E-02 1. 46E-0l 1. 94E-Ol 

3.00E+OO 7.S9E-03 2.0lE-02 1.17E-Ol 3.11E-Ol 

4.00E+OO 6.40E-03 2.6SE-02 6. S5E-02 3.77E-Ol 

5.00E+OO 5. 24E-03 3.lBE-02 3. 23E-02 4.09E-Ol 

6.00E+OO 4. 24E-03 3.60E-02 1.53E-02 4.24E-Ol 

7.00E+OO 3.40E-03 3. 94E-02 7.2lE-03 4.3lE-Ol 

8.00E+OO 2. 72E-03 4.2lE-02 3.45E-03 4.35E-Ol 

9.00E+OO 2.l8E-03 4. 43E-02 1.70E-03 4.37E-Ol 

1.OOE+Ol 1.74E-03 4.6lE-02 B.77E-04 4.37E-Ol 

2.00E+Ol 2.0lE-04 5. 23E-02 1. 22E-04 4.39E-OI 

3.00E+Ol 4.77E-05 5.32E-02 1.20E-04 4.4lE-Ol 

4.00E+Ol 3.24E-OS 5. 36E-02 1.18E-04 4.42E-Ol 

5.00E+Ol 3.08E-OS S.39E-02 1.16E-04 4.43E-Ol 

6.00E+Ol 3.0SE-05 5. 42E-02 1.lSE-04 4. 44E-Ol 

7.00E+Ol 3.04E-OS S.4SE-02 1.13E-04 4.4SE-Ol 

B.OOE+Ol 3.03E-OS 5.4BE-02 1.12E-04 4.46E-Ol 

9.00E+Ol 3.02E-OS 5. SlE-02 1.lOE-04 4.47E-OI 

I.OOE+02 3.00E-OS 5.S4E-02 1.09E-04 4. 49E-Ol 

2.00E+02 2. 89E-OS S.83E-02 9 .. 46E-OS 4.S9E-Ol 

3.00E+02 2.77E-OS 6.l2E-02 8.23E-OS 4. 68E-OI 

4.00E+02 2.6SE-OS 6.39E-02 7.l7E-OS 4.7SE-Ol 

S.OOE+02 2.S3E-OS 6.6SE-02 6. 24E-OS 4.B2E-Ol 

7.00E+02 2. 29E-OS 7.l3E-02 4.73E-OS 4. 93E-Ol 

B.OOE+02 2.l7E-OS 7. 35E-02 4.l2E-OS 4. 97E-Ol 

9.00E+02 2.06E-OS 7.S6E-02 3.S8E-OS S.OlE-OI 

I.OOE+03 1.9SE-OS 7. 76E-02 3.12E-OS S.04E-OI 

2.00E+03 1.07E-OS 9.24E-02 7.80E-06 S.2lE-Ol 

3.00E+03 S.60E-06 1.OOE-Ol 1. 95E-06 S.2SE-Ol 

4.00E+03 2.86E-06 1.04E-Ol 4. 87E-07 S.27E-Ol 

S.OOE+03 1.4SE-06 1.06E-Ol 1. 22E-07 S.27E-Ol 

7.00E+03 3.6SE~07 1.08E-Ol O.OOE+OO S.27E-Ol 

8.00E+03 1. 83E-07 I.08E-OI O.OOE+OO S.27E-OI 

9.00E+03 9.l3E-08 1.08E-Ol O.OOE+OO S.27E-Ol 

1.OOE+04 4.S7E-OB I.08E-Ol O.OOE+OO S.27E-Ol 

B-438 
CLASS Y AHAD = 1 MICRON BALFLIFE= 7~95E+03 DAYS ACTINIUH 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.S3E-03 3.04E-0l 2.5SE-01 7.30E-02 6.39E-Ol 

2.00E-Ol 3. 79E-03 2.SSE-01 2.17E-01 1. 33E-01 6.39E-0l 

3.00E-Ol 3.7SE-03 2.70E-:Ol 1. S2E-01 1. S2E-0l 6.3SE-Ol 

4.00E-Ol 3.7SE-03 2.S7E-Ol 1.S3E-Ol 2.21E-01 6.36E-Ol 

5.00E-01 3.79E-03 2.47E-Ol 1. 29E-01 2.52E-Ol 6.32E-01 

6.00E-Ol 3.S0E-03 2.3SE-Ol I.OSE-01 2. 76E-01 6.27E-0l 

7.00E-Ol 3.S2E-03 2.31E-Ol 9.12E-02 2.93E-OI 6. 19E-Ol 

S.OOE-Ol 3.S3E-03 2.24E-Ol 7. 67E-02 3.0SE-01 6. IOE-Ol 

9.00E-Ol 3.S4E-03 2. 19E-01 6.45E-02 3.I2E-01 5. 99E-OI 

1.00E+OO 3.S6E-03 2.l3E-Ol S.42E-02 3.15E-Ol 5.S7E-Ol 

2.00E+OO 3. 94E-03 1. SOE-Ol 9.S9E-03 2.32E-OI 4. 26E-01 

3.00E+OO 3.9SE-03 1. 65E-OI 1. 69E-03 1. 25E-Ol 2. 95E-Ol 

4.00E+OO 4.00E-03 1.S7E-Ol 3.00E-04 6.06E-02 2. 22E-Ol 

5.00E+OO 4.02E .... 03 . 1. 53E-Ol 5.30E-05 2.S5E-02 I.S5E-Ol 

6.00E+OO 4.04E-03 1.SOE-Ol 9. 36E-06 I.34E-02 I.6SE-Ol 

7.00E+OO 4.05E-03 1. 49E-Ol 1. 65E-06 6.43E-03 I.60E-01 

S.OOE+OO 4.07E-03 1.49E-Ol 2.92E-07 3.I7E-03 1.S6E-OI 

9.00E+OO 4.09E-03 I.4SE-Ol S.17E-OS 1.6SE-03 1.S4E-OI 

1.OOE+01 4.10E-03 I.4SE-01 O.OOE+OO 9.I9E-04 1.S3E-OI 

2.00E+01 4.25E-03 1.46E-01 O.OOE+OO. 2. 36E-04 1.SlE-Ol 

3.00E+01 4.41E-03 1.45E-0l O.OOE+OO 2. 32E-04 1. 49E-0l 

4.00E+01 4.56E-03 1. 43E-01 O.OOE+OO 2.2SE-04 1.4SE-Ol 

5.00E+01 4.71E-03 1.41E-0l O.OOE+OO 2.2SE-04 I.46E-01 

6.00E+OI 4.S7E-03 1.40E-Ol O.OOE+OO 2. 22E-04 1.4SE-01 

7.00E+01 S.02E-03 1.3SE ... 01 O.OOE+OO 2.ISE-04 I.43E-Ol 

S.OOE+01 5.1SE-03 1.37E-OI O.OOE+OO 2. 15E-04 I.42E-Ol 

9.00E+01 5. 33E-03 1.35E-OI O.OOE+OO 2.12E-04 1.4IE-0l 

I.OOE+02 5.4SE-03 1. 34E-OI O.OOE+OO 2.09E-04 I.39E-OI 

2.00E+02 7.03E-03 I.20E-OI O.OOE+OO 1. SOE-04 I.27E-01 

3.00E+02 S.57E-03 I.07E-OI O.OOE+OO 1.S6E-04 1. 16E-01 

4.00E+02 I.OIE-02 9. 64E-02 O.OOE+OO 1.34E-04 I.07E-01 

5.00E+02 1.I6E-02 S.67E-02 O.OOE+OO 1.I6E-04 9.S4E-02 

6.00E+02 1.30E-02 7.SIE-02 O.OOE+OO I.OOE-04 9.l2E-02 

7.00E+02 1.43E-02 7.05E-02 O.OOE+OO S.63E-05 S.49E-02 

S.OOE+02 1. 56E-02 6.37E-02 O.OOE+OO 7.45E-OS 7. 94E-02 

9.00E+02 1.6SE-02 5. 76E-02 O.OOE+OO 6.43E-05 7. 45E-02 

I.OOE+03 1. SOE-02 S.22E-02 O.OOE+OO S.55E-OS 7.03E-02 

2.00E+03 2.S5E-02 2.14E-02 O.OOE+OO I.27E-05 4. 69E-02 

3.00E+03 2. 77E-02 I.03E-02 O.OOE+OO 2.9lE-06 3.S0E-02 

4.00E+03 2.70E-02 5.S2E-03 O.OOE+OO 6.67E-07 3.2SE-02 

5.00E+03 2.51E-02 3.S3E-03 O.OOE+OO I.53E-07 2.S9E-02 

7.00E+03 2.0SE-02 2. 32E-03 O.OOE+OO O.OOE+OO 2.2SE-02 

S.OOE+03 1.S3E-02 1. 99E-03 O.OOE+OO O.OOE+OO 2.03E-02 

9.00E+03 I. 63E-02 I.77E-03 O.OOE+OO O.OOE+OO 1.SIE-02 

I.OOE+04 1.45E-02 I.S9E-03 O.OOE+OO O.OOE+OO I.6IE-02 

2.00E+04 4.4SE-03 6.S4E-04 O.OOE+OO O.OOE+OO 5.l3E-03 

B-439 
ClASS Y AMAD = 1 KICRON HALFLIFE= 7. 95E+03 DAYS ACTINIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------~----~-------------------------------

SYSTEMIC NON-SYSTEMIC 

-~----------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 8.19E-05 1.04E-05 

2.00E-01 1. 57E-04 2.10E-04 

3.00E-01 2. 15E-04 1.06E-03 

4.00E-Ol 2. 59E-04 3.07E-03 

5.00E-01 2.95E-04 6. 66E-03 

6.00E-Ol 3. 22E-04 1.21E-02 

7.00E-Ol 3. 44E-04 1. 94E-02 

8.00E-01 3. 62E-04 2.86E-02 

9.00E-01 3.76E-04 3. 96E-02 

1.00E+00 3. 87E-04 3. 87E-04 5.21E-02 5. 21E-02 

2.00E+00 4. 32E-05 4.30E-04 1.61E-Ol 2. 13E-01 

3.00E+00 8. 67E-06 4. 39E-04 1.31E-01 3. 43E-01 

4.00E+OO 3.71E-06 4.42E-04 7. 35E-02 4. 17E-01 

5.00E+00 2. 58E-06 4. 45E-04 3. 64E-02 4. 53E-01 

6.00E+00 2.19E-06 4.47E-04 1.72E-02 4.70E-01 

7.00E+00 2.03E-06 4.49E-04 8. 12E-03 4. 78E-01 

8.00E+00 1.95E-06 4.51E-04 3.88E-03 4.82E-01 

9.00E+00 1.91E-06 4. 53E-04 1.91E-03 4.84E-Ol 

1.00E+Ol 1.90E-06 4. 55E-04 9. 84E-04 4. 85E-01 

2.00E+01 . 1.89E-06 4. 73E-04 1. 35E-04 4.87E-01 

3.00E+Ol 1.90E-06 4.92E-04 1.33E-04 4. 88E-Ol 

4.00E+Ol 1.91E-06 5.10E-04 1.31E-04 4.89E-Ol 

5.00E+Ol 1.92E-06 5. 29E-04 1.29E-04 4.90E-Ol 

7.00E+Ol 1. 94E-06 5. 67E-04 1. 25E-04 4.91E-Ol 

8.00E+01 1. 95E-06 5. 86E-04 1. 23E-04 4.92E-Ol 

9.00E+Ol 1. 96E-06 6.05E-04 1.21E-04 4. 93E-Ol 

1.00E+02 1. 97E-06 6. 24E-04 1.20E-04 4. 94E-Ol 

2.00E+02 2.04E-06 8. 18E-04 1.03E-04 5.00E-01 

3.00E+02 2.09E-06 1.02E-03 8.90E-05 5.06E-Ol 

4.00E+02 2. 12E-06 1. 22E-03 7. 68E-05 5.09E-01 

5.00E+02 2. 13E-06 1. 42E-03 6. 63E-05 5. 12E-01 

7.00E+02 2. 13E-06 1. 82E-03 4. 94E-05 5. 15E-01 

8.00E+02 2.11E-06 2.01E-03 4.26E-05 5.15E-01 

9.00E+02 2.09E-06 2.20E-03 3. 68E-05 5. 14E-Ol 

1.00E+03 2.06E-06 2. 39E-03 3.17E-05 5. 13E-Ol 

2.00E+03 1.66E-06 3. 98E-03 7.27E-06 4. 86E-Ol 

3.00E+03 1. 32E-06 5.06E-03 1.67E-06 4. 49E-Ol 

4.00E+03 1.08E-06 5. 78E-03 3.82E-07 4.12E-01 

'5.00E+03 9.08E-07 6. 24E-03 8. 75E-08 3. 78E-Ol 

7.00E+03 6. 78E-07 6. 68E-03 O.OOE+OO 3. 18E-Ol 

8.00E+03 5. 94E-07 6. 73E-03 O.OOE+OO 2.91E-Ol 

9.00E+03 5. 22E-07 6.70E-03 O.OOE+OO 2. 67E-Ol 

1.00E+04 4.60E-07 6.61E-03 O.OOE+OO 2.45E-Ol 

2.00E+04 1. 33E-07 4. 36E-03 O.OOE+OO 1.02E-Ol 

B-440 
CLASS Y AJfAD = 1 HICRON BALFLIFE== 1.87E+Ol DAYS THORIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3.S4E-03 3.03E-Ol 2.S7E-OI 7.2SE-02 6. 37E-OI 

2.00E-OI 3. 79E-03 2.S3E-OI 2.1SE-OI 1. 32E-OI 6. 34E-OI 

3.00E-OI 3.75E-03 2.67E-0l I.SOE-Ol 1. SOE-Ol 6.31E-OI 

4.00E-OI 3.72E-03 2. 54E-OI l.5IE-OI 2. ISE-OI 6.27E-OI 

5.00E-Ol 3~ 6SE-03 2. 43E-0l 1.27E-0l 2.48E-0l 6.21E-OI 

6.00E-OI 3. 65E-03 2. 33E-OI I.06E-OI 2.70E-Ol 6.13E-Ol 

7.00E-Ol 3. 62E-03 2.25E-0l S.89E-02 2. S6E-Ol 6.04E-OI 

S.OOE-OI 3.60E-03 2. ISK-Ol 7.4SE-02 2. 97E-OI 5. 92E-OI 

9.00E-Ol 3.5SE-03 2.11E-OI 6. 24E-02 3.02E-OI S.80E-OI 

I.OOE+OO 3.5SE-03 2.06E-OI 5. 23E-02 3.04E-OI S.6SE-OI 

2.00E+OO 3.38E-03 1. 68E-OI 8.9IE-03 2.16E-OI 3.96E-OI 

3.00E+OO 3. 26E-03 1.47E-Ol 1. S2E-03 I.I2E-OI 2. 64E-Ol 

4.00E+OO 3. ISE-03 I.3SE-OI 2.5SE-04 5.24E-02 1.9IE-OI 

S.OOE+OO 3.0SE-03 I.27E-Ol 4.40E-05 2.37E-02 1. S4E-OI 

6.00E+OO 2.9SE-03 I.2IE-0l 7. SOE-06 I.OSE-02 1.34E-Ol 

7.00E+OO 2.S6E-03 1. ISE-Ol 1.2SE-06 4. 97E-03 1. 23E-OI 

S.OOE+OO 2.76E-03 I.llE-OI 2. ISE-07 2.36E-03 1.16E-Ol 

9.00E+OO 2. 67E-03 I.06E-Ol 3.71E-08 1.18E-03 I.lOE-Ol 

1.OOE+0l 2.59E-03 I.02E-OI O.OOE+OO 6.36E-04 1.OSE-0l 

2.00E+Ol 1.8SE-03 6.9SE-02 O.OOE+OO 1.I3E-04 7.ISE-02 

3.00E+OI I.33E-03 4.77E-02 O.OOE+OO 7.65E-05 4.9lE-02 

4.00E+Ol 9.SIE-04 3. 26E-02 O.OOE+OO 5.2IE-05 3. 36E-02 

S.OOE+OI 6.S0E-04 2.23E-02 O.OOE+OO 3. SSE-OS 2.30E-02 

6.00E+Ol 4.SSE-04 1.S2E-02 O.OOE+OO 2. 42E-05 I.S7E-02 

7.00E+Ol 3. 46E-04 1.04E-02 O.OOE+OO 1.6SE-OS 1.OSE-02 

8.00E+Ol 2. 47E-04 7.l2E-03 O.OOE+OO 1.12E-OS 7.3SE-03 

9.00E+Ol I.76E-04 4. 86E-03 O.OOE+OO 7.64E-06 S.OSE-03 

1.OOE+02 1.2SE-04 3. 33E-03 O.OOE+OO S.20E-06 3. 46E-03 

2.00E+02 3.98E-06 7.4IE-OS O.OOE+OO I.I2E-07 7.8IE-OS 

3.00E+02 1.20E-07 1. 65E-06 O.OOE+OO O.OOE+OO I.77E-06 

B-44I 
CLASS Y AHAD = 1 KICRON BALFLIFK= 1.87E+Ol DAYS mORIUM 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -----~-~-------------------------------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ------~----------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.3SE-OS 1.08E-OS 

2.00E-Ol 8.80E-OS 2.09E-04 

3.00E-Ol 1.27E-04 1.OSE-03 

4.00E-Ol 1.60E-04 3.03E-03 

S.OOE-Ol 1.89E-04 6.SSE-03 

6.00E-Ol 2.l4E-04 1.18E-02 

7.00E-Ol 2.36E-04 1.89E-02 

8.00E-Ol 2.SSE-04 2. 78E-02 

9.00E-Ol 2.71E-04 3. 83E-02 

1.OOE+OO 2.8SE-04 2.8SE-04 S.02E-02 5.02E-02 

2.00E+OO 7.5lE-OS 3.49E-04 1.49E-Ol 1.98E-0l 

3.00E+OO 2.07E-OS 3. 57E-04 1.l7E-Ol 3.08E-Ol 

4.00E+OO 6. 99E-06 3.5lE-04 6.3SE-02 3.60E-Ol 

S.OOE+OO 3.51E-06 3.42E-04 3.03E-02 3.77E-Ol 

6.00E+OO 2. 56E-06 3. 32E-04 1.38E-02 3.77E-Ol 

7.00E+OO 2.25E-06 3. 22E-04 6. 27E-03 3.70E-Ol 

8.00E+OO 2.11E-06 3.l3E-04 2.89E-03 3. 59E-Ol 

9.00E+OO 2.02E-06 3.03E-04 1.37E-03 3.48E-Ol 

1.OOE+Ol 1.94E-06 2. 94E-04 6.8lE-04 3.36E-Ol 

2.00E+Ol 1.36E-06 2.l7E-04 6.47E-OS 2.33E-Ol 

3.00E+Ol 9.53E-07 1.59E-04 4. 38E-05 1.61E-Ol 

4.00E+Ol 6. 68E-07 1.17E-04 2. 98E-OS 1.12E-Ol 

5.00E+Ol 4. 68E-07 8.S1E-OS 2.03E-OS 7. 73E-02 

6.00E+Ol 3. 28E-07 6.20E-OS 1. 38E-05 S.35E-02 

7.00E+0l 2.30E-07 4.51E-OS 9. 42E-06 3.70E-02 

8.00E+Ol 1.6lE-07 3. 28E-OS 6. 42E-06 2. 56E-02 

9.00E+Ol 1. 12E-07 2.37E-OS 4. 37E-06 1.77E-02 

1.00E+02 7. 87E-08 1.72E-05 2. 98E-06 1. 23E-02 

B-442 
CLASS Y AMAD = 1 KICRON BALFLIFK= 2.81&+07 DAYS THORIUM 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 86E-03 3.04E-Ol 2. 58E-01 7.31E-02 6.39E-01 

2.00E-Ol 3.82E-03 2. 85E-01 2. 17E-01 1.33E-01 6. 39E-01 

3.00E-01 3.79E-03 2.70E-01 1. 82E-01 1.82E-01 6.38E-Ol 

4.00E-Ol 3.77E-03 2. 57E-01 1. 53E-Ol 2.21E-Ol 6. 36E-Ol 

5.00E-Ol 3.75E-03 2.47E-Ol 1.29E-Ol 2. 52E-Ol 6.32E-Ol 

6.00E-Ol 3. 73E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6.27E-Ol 

7.00E-Ol 3.72E-03 2.31E-Ol 9. 12E-02 2.94E-01 6.19E-Ol 

8.00E-Ol 3.71E-03 2. 24E-Ol 7. 67E-02 3.05E-Ol 6.1OE-01 

9.00E-Ol 3.70E-03 2. 19E-Ol 6. 45E-02 3. 13E-Ol 5. 99E-01 

1.00E+00 3. 69E-03 2. 13E-Ol 5. 42E-02 3. 15E-Ol 5.87E-Ol 

2.00E+00 3.65E-03 1.80E-Ol 9. 59E-03 2.32E-Ol 4.26E-Ol 

3.00E+00 3. 65E-03 1. 65E-Ol 1.70E-03 1. 25E-Ol 2. 95E-Ol 

4.00E+00 3.66E-03 1.57E-01 3.00E-04 6.07E-02 2.21E-Ol 

5.00E+00 3. 67E-03 1. 53E-01 5.30E-05 2. 86E-02 1. 85E-Ol 

6.00E+00 3. 69E-03 1.51E-Ol 9. 37E-06 1. 34E-02 1.68E-Ol 

7.00E+00 3.70E-03 1.49E-Ol 1. 66E-06 6.44E-03 1.60E-Ol 

8.00E+00 3.71E-03 1.49E-Ol 2. 93E-07 3. 18E-03 1. 56E-Ol 

9.00E+00 3. 73E-03 1. 48E-Ol 5. 17E-08 1. 65E-03 1. 54E-Ol 

1.00E+Ol 3. 74E-03 1.48E-Ol O.OOE+OO 9.20E-04 1. 53E-Ol 

2.00E+Ol 3.89E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1.51E-Ol 

3.00E+Ol 4.04E-03 1.45E-Ol O.OOE+OO 2. 32E-04 1.49E-Ol 

4.00E+Ol 4. 18E-03 1. 43E-Ol O.OOE+OO 2. 29E-04 1.48E-Ol 

5.00E+Ol 4. 33E-03 1.42E-Ol O.OOE+OO 2.26E-04 1.47E-Ol 

6.00E+Ol 4. 48E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1.45E-Ol 

7.00E+Ol 4. 62E-03 1.39E-01 O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+Ol 4.77E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1. 43E-Ol 

9.00E+Ol 4. 92E-03 1.36E-Ol O.OOE+OO 2. 14E-04 1.41E-Ol 

1.00E+02 5.07E-03 1. 35E-Ol O.OOE+OO 2. l1E-04 1.40E-Ol 

2.00E+02 6. 55E-03 1. 22E-Ol O.OOE+OO 1. 84E-04 1. 29E-Ol 

3.00E+02 8.02E-03 1.10E-Ol O.OOE+OO 1.60E-04 1. 18E-Ol 

4.00E+02 9. 46E-03 9.98E-02 O.OOE+OO 1.39E-04 1.09E-Ol 

5.00E+02 1.09E-02 9.06E-02 O.OOE+OO 1.21E-04 1.02E-Ol 

6.00E+02 1.22E-02 8. 23E-02 O.OOE+OO 1.05E-04 9. 46E-02 

7.00E+02 1. 35E-02 7. 49E-02 O.OOE+OO 9. 18E-05 8. 85E-02 

8.00E+02 1.47E-02 6. 83E-02 O.OOE+OO 7.99E-05 8.31E-02 

9.00E+02 1. 59E-02 6. 23E-02 O.OOE+OO 6. 96E-05 7. 83E-02 . '-,' ' 1.00E+03 1.70E-02 -~ . . . 5.70E-02 O.OOE+OO 6.06E-05 7.41E-02 

2.00E+03 2. 44E-02 2. 55E-02 O.OOE+OO 1. 51E-05 4. 98E-02 

3.00E+03 2. 68E-02 1.34E-02 O.OOE+OO 3.78E-06 4.02E-02 

4.00E+03 2. 67E-02 8. 25E-03 O.OOE+OO 9.46E-07 3.50E-02 

5.00E+03 2. 55E-02 5. 92E-03 O.OOE+OO 2.37E-07 3. 14E-02 

7.00E+03 2.20E-02 4. 27E-03 O.OOE+OO 1. 48E-08 2. 63E-02 

8.00E+03 2.03E-02 4.00E-03 O.OOE+OO O.OOE+oo 2. 43E-02 

9.00E+03 1.87E-02 3. 87E-03 O.OOE+OO O.OOE+OO 2. 25E-02 

1.00E+04 1.71E-02 3.80E-03 O.OOE+OO O.OOE+oo 2.09E-02 

2.00E+04 7.21E-03 3. 74E-03 O.OOE+OO O.OOE+OO 1.09E-02 

B-443 
CLASS Y AHAD = 1 MICRON BALFLIPE= 2.81E+07 DAYS mORIUM 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4. 37E-05 1.09E-05 

2.00E-Ol 8. 87E-OS 2. llE-04 

3.00E-Ol 1.28E-04 1.06E-03 

4.00E-Ol 1. 62E-04 3.07E-03 

S.OOE-Ol 1. 93E-04 6.67E-03 

6.00E-Ol 2.I9E-04 1.2lE-02 

7.00E-Ol 2. 42E-04 1.94E-02 

8.00E-Ol 2. 62E-04 2. 86E-02 

9.00E-01 2.80E-04 3.96E-02 

I.OOE+OO 2.9SE-04 2.9SE-04 S.2lE-02 S.2lE-02 

2.00E+OO 8.09E-05 3.76E-04 1.6lE-Ol 2. 13E-01 

3.00E+OO 2.3lE-OS 3. 99E-04 1.3IE-01 3. 44E-Ol 

4.00E+OO 8. llE-06 4.07E-04 7.36E-02 4.l7E-Ol 

S.OOE+OO 4. 22E-06 4.l2E-04 3. 64E-02 4. 54E-Ol 

6.00E+OO 3.l9E-06 4. ISE-04 1.73E-02 4.7lE-OI 

7.00E+OO 2. 92E-06 4.l8E-04 8. 13E-03 4. 79E-OI 

S.OOE+OO 2.S4E-06 4.21E-04 3.8SE-03 4.S3E-Ol 

9.00E+OO 2. 82E-06 4. 23E-04 I.91E-03 4.8SE-01 

1.00EtOl 2.SlE-06 4.26E-04 9. SSE-04 4. 86E-Ol 

2.00E+01 2.SSE-06 4.SSE-04 1.36E-04 4. 88E-01 

3.00E+Ol 2.S9E-06 4. 83E-04 1. 33E-04 4.89E-Ol 

4.00E+OI 2. 94E-06 S.12E-04 I.31E-04 4.9lE-Ol 

5.00E+OI 2.9SE-06 5. 42E-04 1.29E-04 4.92E-Ol 

7.00E+Ol 3.07E-06 6.03E-04 1. 26E-04 4.9SE-01 

S.OOE+01 3. llE-06 6. 34E-04 1.24E-04 4. 96E-01 

9.00E+01 3.1SE-06 6.6SE-04 1. 22E-04 4.97E-01 

1.OOE+02 3.l9E-06 6. 97E-04 1.21E-04 4.98E-Ol 

2.00E+02 3.5SE-06 1.04E-03 I.OSE-04 S.lOE-Ol 

3.00E+02 3. 93E-06 1.41E-03 9. ISE-05 5. 19E-01 

4.00E+02 4. 24E-06 1. 82E-03 7.97E-OS 5.2SE-01 

5.00E+02 4.S1E-06 2. 26E-03 6.94E-OS 5.3SE-01 

7.00E+02 4. 95E-06 3.21E-03 S.26E-OS S.47E-01 

S.OOE+02 S.11E-06 3.71E-03 4. S8E-OS S.S2E-Ol 

9.00E+02 5.2SE-06 4. 23E-03 3. 99E-OS S.S7E-Ol 

1.OOE+03 S.36E-06 4. 76E-03 3. 47E-OS S.60E-01 

2.00E+03 5. 36E-06 1.02E-02 8. 72E-06 S.79E-Ol 

3.00E+03 4.S1E-06 1.S2E-02 2.2lE-06 S.84E-01 

4.00E+03 3. 64E-06 1. 93E-02 S.78E-07 S.85E-01 

S.OOE+03 2. 96E-06 2.2SE-02 1.6SE-07 S.8SE-01 

7.00E+03 2. 13E-06 2.7SE-02 2. 97E-OS 5.85E-Ol 

8.00E+03 1.87E-06 2.9SE-02 2.08E-OS S.8SE-Ol 

9.00E+03 1. 68E-06 3.13E-02 1.73E-OS 5.8SE-Ol 

1.00E+04 1.SlE-06 3.29E-02 I.S3E-08 S.8SE-Ol 

2.00E+04 6.2SE-07 4. 29E-02 O.OOE+OO S.SSE-Ol 

B-444 
CLASS Y AHA» "" 1 KICRON HALFLIFK= 5. 13E+ 12 DAYS THORIUM 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-Ol 3. 86E-03 3.04E-01 2.58E-Ol 7.31E-02 6. 39E-Ol 

2.00E-Ol 3. 82E-03 2. 85E-Ol 2. 17E-Ol 1.33E-Ol 6. 39E-Ol 

3.00E-Ol 3.79E-03 2.70E-Ol 1.82E-Ol 1.82E-Ol 6. 38E-Ol 

4.00E-Ol 3.77E-03 2. 57E-Ol 1. 53E-Ol 2.21E-Ol 6. 36E-Ol 

5.00E-Ol 3.75E-03 2.47E-Ol 1.29E-Ol 2. 52E-Ol 6.32E-Ol 

6.00E-Ol 3.73E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6.27E-Ol 

7.00E-Ol 3.72E-03 2.31E-Ol 9. 12E-02 2. 94E-Ol 6.19E-Ol 

8.00E-Ol 3. 71E-03 2. 24E-Ol 7. 67E-02 3.05E-Ol 6.IOE-Ol 

9.00E-Ol 3.70E-03 2. 19E-Ol 6.45E-02 3. 13E-Ol 5.99E-Ol 

1.00E+00 3. 69E-03 2.13E-Ol 5.42E-02 3. 15E-Ol 5.87E-Ol 

2.00E+00 3. 65E-03 1.80E-Ol 9. 59E-03 2.32E-Ol 4.26E-Ol 

3.00E+00 3.65;::-03 1.65E-Ol 1.70E-03 1.25E-Ol 2. 95E-Ol 

4.00E+00 3. 66E-03 1.57E-01 3.00E-04 6.07E-02 2.21E-Ol 

5.00E+00 3. 67E-03 1. 53E-Ol 5.30E-05 2. 86E-02 1. 85E-Ol 

6.00E+00 3. 69E-03 1.51E-Ol 9.37E-06 1. 34E-02 1.68E-Ol 

7.00E+QO 3.70E-03 1.49E-Ol 1.66E-06 6.44E-03 1.60E-Ol 

8.00E+00 3. 71E-03 1. 49E-01 2.93E-07 3. 18E-03 1.56E-Ol 

9.00E+00 3. 73E-03 1.48E-Ol 5. 17E-08 1. 65E-03 1. 54E-Ol 

1.00E+Ol 3. 74E-03 1.48E-Ol O.OOE+OO 9.20E-04 1. 53E-Ol 

2.00E+Ol 3. 89E-03 1. 46E-Ol O.OOE+OO 2. 36E-04 1.51E-Ol 

3.00E+Ol 4.04E-03 1.45E-Ol O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+Ol 4. 18E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.48E-Ol 

5.00E+Ol 4. 33E-03 1.42E-Ol O.OOE+OO 2. 26E-04 1.47E-Ol 

6.00E+Ol 4. 48E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1. 45E-Ol 

7.00E+Ol 4. 62E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+Ol 4.77E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1.43E-Ol 

9.·00E+Ol 4. 92E-03 1. 36E-Ol O.OOE+OO 2. 14E-04 1.41E-Ol 

1.00E+02 5.07E-03 1.35E-Ol O.OOE+OO 2. l1E-04 1.40E-Ol 

2.00E+02 6. 55E-03 1.22E-Ol O.OOE+OO 1.84E-04 1.29E-Ol 

3.00E+02 8.02E-03 1.10E-Ol O.OOE+OO 1.60E-04 1. 18E-Ol 

4.00E+02 9.46E-03 9. 98E-02 O.OOE+OO 1.39E-04 1.09E-Ol 

5.00E+02 1.09E-02 9.06E-02 O.OOE+OO 1.21E-04 1.02E-Ol 

6.00E+02 1.22E-02 8. 23E-02 O.OOE+OO 1.05E-04 9. 46E-02 

7.00E+02 1. 35E-02 7.49E-02 O.OOE+OO 9. 18E-05 8. 85E-02 

8.00E+02 1. 47E-02 6. 83E-02 O.OOE+OO 7. 99E-05 8.31E-02 

9.00E+02 1. 59E-02 6. 23E-02 O.OOE+OO 6. 96E-05 7. 83E-02 

" ''-'''; 

1.00E+03 1.70E-02 5.70E-02 O.OOE+oo 6.06E-05 7.41E-02 

2.00E+03 2.44E-02 2. 55E-02 O.OOE+OO 1.51E-05 4. 98E-02 

3.00E+03 2. 68E-02 1.34E-02 O.OOE+OO 3. 79E-06 4.02E-02 

4.00E+03 2. 67E-02 8. 25E-03 O.OOE+OO 9.46E-07 . 3.50E-02 

5.00E+03 2. 55E-02 5.92E-03 O.OOE+OO 2. 37E-07 3. 14E-02 

7.00E+03 2.20E-02 4. 27E-03 O.OOE+OO 1. 48E-08 2. 63E-02 

8.00E+03 2.03E-02 4.00E-03 O.OOE+OO O.OOE+OO 2. 43E-02 

9.00E+03 1. 87E-02 3. 87E-03 O.OOE+OO O.OOE+OO 2. 25E-02 

1.00E+04 1.71E-02 3.80E-03 O.OOE+OO O.OOE+OO 2.09E-02 

2.00E+04 7. 22E-03 3. 74E-03 O.OOE+OO O.OOE+OO 1.10E-02 

B-445 
CLASS Y AlIAD = 1 MICRON BALFLIFE= 5.lJE+ 12 DAYS mORIUM 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --------~-------------- 24-HOUR ACCmfULATED 24-HOUR ACCmfULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-OI 4. 37E-05 I.09E-05 

2.00E-Ol 8.87E-05 2.llE-04 

3.00E-Ol 1. 28E-04 I.06E-03 

4.00E-Ol 1. 62E-04 3.07E-03 

5.00E-Ol 1.93E-04 6. 67E-03 

6.00E-Ol 2.l9E-04 I.2IE-02 

7.00E-OI 2. 42E-04 1.94E-02 

8.00E-OI 2. 62E-04 2. 86E-02 

9.00E-Ol 2.80E-04 3. 96E-02 

I.OOE+OO 2. 95E-04 2. 95E-04 5.2lE-02 5.2IE-02 

2.00E+OO 8.09E-05 3. 76E-04 1.6lE-OI 2.l3E-OI 

3.00E+OO 2.3IE-05 3. 99E-04 1.31E-OI 3. 44E-OI 

4.00E+OO 8.11E-06 4.07E-04 7.36E-02 4.17E-OI 

5.00E+OO 4. 22E-06 4.12E-04 3. 64E-02 4. 54E-OI 

6.00E+OO 3.19E-06 4.15E-04 1. 73E-02 4.7IE-OI 

7.00E+OO 2. 92E-06 4.18E-04 8.l3E-03 4. 79E-OI 

8.00E+OO 2. 84E-06 4.2lE-04 3.88E-03 4.83E-OI 

9.00E+OO 2.82E-06 4. 23E-04 1.9IE-03 4. 85E-OI 

1.OOE+Ol 2.8lE-06 4. 26E-04 9.85E-04 4. 86E-OI 

2.00E+Ol 2. 85E-06 4. 55E-04 1. 36E-04 4. 88E-OI 

3.00E+Ol 2.89E-06 4. 83E-04 I.33E-04 4.89E-Ol 

4.00E+OI 2. 94E-06 5.12E-04 I.3IE-04 4.9IE-OI 

5.00E+OI 2. 98E-06 5. 42E-04 1. 29E-04 4.92E-OI 

7.00E+OI 3.07E-06 6.03E-04 1. 26E-04 4. 95E-Ol 

8.00E+Ol 3.llE-06 6. 34E-04 I.24E-04 4. 96E-Ol 

9.00E+Ol 3.15E-06 6. 65E-04 1. 22E-04 4. 97E-OI 

I.OOE+02 3.19E-06 6. 97E-04 1.21E-04 4. 98E-Ol 

2.00E+02 3. 58E-06 I.04E-03 1.05E-04 5.10E-OI 

3.00E+02 3. 93E-06 1.4IE-03 9. 15E-05 5.19E-OI 

4.00E+02 4. 24E-06 1. 82E-03 7. 97E-05 5. 28E-OI 

5.00E+02 4.5IE-06 2.26E-03 6. 94E-05 5. 35E-OI 

7.00E+02 4. 95E-06 3.2IE-03 5. 26E-05 5.47E-OI 

8.00E+02 5.IIE-06 3.7lE-03 4. 58E-05 5.52E-OI 

9.00E+02 5. 25E-06 4. 23E-03 3. 99E-05 5. 57E-Ol 

I.OOE+03 5. 36E-06 4. 76E-03 3.47E-05 5.60E-OI 

2.00E+03 5. 36E-06 I.02E-02 8.72E-06 5. 79E-Ol 

3.00E+03 4.51E-06 I.52E-02 2.21E-06 5. 84E-Ol 

4.00E+03 3.64E-06 1. 93E-02 5. 78E-07 5.85E-Ol 

5.00E+03 2.96E-06 . 2. 26E-02 1.65E-07 5.85E-Ol 

7.00E+03 2. 13E-06 2. 75E-02 2. 97E-08 5. 86E-Ol 

8.00E+03 1.87E-06 2. 95E-02 2.09E-08 5.86E-Ol 

9.00E+03 1. 68E-06 3. 13E-02 I.73E-08 5.86E-Ol 

1.00E+04 1. 52E-06 3. 29E-02 1.53E-08 5.86E-Ol 

2.00E+04 6. 25E-07 4. 29E-02 O •. OOE+OO 5. 86E-Ol 

B-446 
CLASS Y .AHAD '"' 1 HICRON If.ALI'LlFE- 2.41E+OI DAYS mORIDM 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 84E-03 3.03E-Ol 2. 57E-Ol 7.28E-02 6. 37E-Ol 

2.00E-Ol 3.80E-03 2. 83E-Ol 2.l6E-Ol 1. 32E-Ol 6~35E-Ol 

3.00E-Ol 3. 76E-03 2.68E-Ol 1.8lE-Ol 1.80E-Ol 6.32E-Ol 

4.00E-Ol 3. 73E-03 2. 54E-Ol 1.S2E-Ol 2.l9E-Ol 6.29E-OI 

5.00E-OI 3.70E-03 2.44E-Ol 1.27E-Ol 2.49E-Ol 6.23E-OI 

6.00E-Ol 3. 67E-03 2. 34E-OI I.07E-OI 2.71E-OI 6.l6E-Ol 

7.00E-Ol 3.6SE-03 2. 26E-OI 8. 94E-02 2. 88E-OI 6.07E-OI 

8.00E-OI 3. 62E-03 2.19E-Ol 7.50E-02 2. 99E-OI 5. 96E-Ol 

9.00E-OI 3.60E-03 2.l3E-OI 6. 29E-02 3.0SE-OI S.84E-01 

1.00E+OO 3.SSE-03 2.07E-Ol 5. 27E-02 3.07E-Ol 5.70E-Ol 

2.00E+OO 3. 44E-03 1.70E-Ol 9.0SE-03 2.l9E-Ol 4.02E-Ol 

3.00E+OO 3. 34E-03 1.5lE-Ol I. 56E-03 1.lSE-Ol 2.7lE-Ol 

4.00E+OO 3. 26E-03 1.40E-Ol 2. 67E-04 5.4IE-02 1. 97E-01 

5.00E+OO 3.l8E-03 1. 32E-01 4. 59E-05 2. 47E-02 1.60E-Ol 

6.00E+OO 3.lOE-03 1.27E-Ol 7. 88E-06 1.13E-02 1.4IE-OI 

7.00E+OO 3.03E-03 1. 22E-Ol 1.3SE-06 S.26E-03 1.30E-OI 

8.00E+OO 2.9SE-03 1.l8E-0l 2. 33E-07 2. S3E-03 I. 24E-OI 

9.00E+OO 2. 88E-03 1.lSE-Ol 3. 99E-08 1. 27E-03 1. 19E-01 

I.OOE+Ol 2.81E-03 1.llE-OI O.OOE+OO 6.90E-04 1.lSE-OI 

2.00E+OI 2.l9E-03 8. 24E-02 O.OOE+OO I. 33E-04 8. 47E-02 

3.00E+OI 1.70E-03 6.12E-02 O.OOE+OO 9. SIE-05 6.30E-02 

4.00E+01 1.32E-03 4.S4E-02 O.OOE+OO 7.2SE-OS 4. 68E-02 

5.00E+OI 1.03E-03 3. 37E-02 O.OOE+OO 5.37E-OS 3. 48E-02 

6.00E+Ol 7. 97E-04 2.50E-02 O.OOE+OO 3. 97E-05 2.59E-02 

7.00E+01 6. 17E-04 1.86E-02 O.OOE+OO 2.94E-05 1.92E-02 

S.OOE+Ol 4. 78E-04 1.3SE-02 O.OOE+OO 2.l7E-05 1. 43E-02 

9.00E+OI 3.70E-04 I.02E-02 O.OOE+OO 1.6IE-05 1.06E-02 

1.00E+02 2. 86E-04 7.60E-03 O.OOE+OO 1.19E-05 7.90E-03 

2.00E+02 2.0SE-05 3.S7E-04 O.OOE+OO 5. 83E-07 4.08E-04 

3.00E+02 I. 43E-06 I. 97E-OS O.OOE+OO 2. 86E-OS 2.12E-05 

4.00E+02 9.S4E-08 I.OIE-06 O.OOE+OO O.OOE+OO I.IOE-06 

'-', ; , 

B-447 
CLASS Y AMAD = 1 MICRON HALFLIFE= 2.41£+01 DAYS THORIUM 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -~----------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.35E-OS 1.09E-05 

2.00E-Ol 8. 82E-05 2.lOE-04 

3.00E-Ol 1. 27E-04 1.05E-03 

4.00E-Ol 1.6lE-04 3.04E-03 

5.00E-Ol 1.90E-04 6. 57E-03 

6.00E-Ol 2.1SE-04 1.19E-02 

7.00E-Ol 2. 37E-04 1.90E-02 

8.00E-Ol 2. 56E-04 2.80E-02 

9.00E-Ol 2. 73E-04 3.86E-02 

1.00E+OO 2. 87E-04 2. 87E-04 5.06E-02 S.06E-02 

2.00E+OO 7. 64E-OS 3. 55E-04 1.52E-0l 2.0lE-OI 

3.00E+OO 2.l2E-OS 3. 66E-04 1.20E-Ol 3. 15E-Ol 

4.00E+OO 7. 23E-06 3. 63E-04 6. 56E-02 3.12E-Ol 

S.OOE+OO 3.6SE-06 3.57E-04 3.l5E-02 3. 93E-Ol 

6.00E+OO 2. 69E-06 3. 49E-04 1.4SE-02 3. 96E-Ol 

7.00E+OO 2. 38E-06 3. 42E-04 6. 65E-03 3. 92E-Ol 

8.00E+OO 2. 26E-06 3. 34E-04 3.09E-03 3.84E-Ol 

9.00E+OO 2.l7E-06 3.27E-04 1. 47E-03 3. 74E-Ol 

1.OOE+Ol 2.llE-06 3.20E-04 7. 39E-04 3. 64E-Ol 

2.00E+Ol 1.60E-06 2. 56E-04 7. 63E-OS 2. 75E-Ol 

3.00E+Ol l.22E-06 2.04E-04 5.6lE-OS 2.07E-Ol 

4.00E+Ol 9.30E-07 l.62E-04 4.l5E-OS 1.SSE-Ol 

S.OOE+Ol 7.08E-07 l.29E-04 3.07E-OS 1. 17E-Ol 

6.00E+Ol S.38E-07 l.02E-04 2. 27E-OS 8. 78E-02 

7.00E+Ol 4.lOE-07 8.0SE-05 1. 68E-OS 6.6lE-02 

8.00E+Ol 3. llE-07 6.3SE-05, 1. 24E-OS 4. 97E-02 

9.00E+Ol 2.37E-07 4. 99E-OS 9.20E-06 3. 73E-02 

1.00E+02 1.80E-07 3. 93E-OS 6.80E-06 2.8lE-02 

2.00E+02 1.14E-08 3. 29E-06 3. 34E-07 1. 62E-03 

B-448 
CLASS Y AMAD = 1 MICRON IlALFLIFB- 1.20E+07 DAYS PROTACTINIOH 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.SSE-03 3.04E-Ol 2.5SE-Ol 7.30E-02 6. 39E-Ol 

2.00E-Ol 3. 26E-03 2.SSE-Ol 2.l7E-Ol 1.33E-Ol 6.3SE-Ol 

3.00E-Ol 3.06E-03 2.70E-Ol 1. S2E-Ol 1.S2E-Ol 6. 37E-Ol 

4.00E-Ol 2.9lE-03 2.S7E-Ol 1.S3E-Ol 2.21E-Ol 6. 35E-Ol 

S.OOE-Ol 2.S0E-03 2.47E-Ol 1.29E-Ol 2. S2E-Ol 6.3lE-Ol 

6.00E-Ql 2. 72E-03 2.3SE-Ol 1.OSE-Ol 2. 76E-Ol 6. 26E-Ol 

7.00E-Ol 2. 65E-03 2.3lE-Ol 9.l2E-02 2. 93E-Ol 6.lSE-Ol 

8.00E-Ol 2.6lE-03 2. 24E-Ol 7. 67E-02 3.0SE-Ol 6.09E-Ol 

9.00E-Ol 2. 57E-03 2.l9E-Ol 6.4SE-02 3.l2E-Ol S.98E-Ol 

1.OOE+OO 2.S4E-03 2.l3E-Ol S.42E-02 3.lSE-Ol S.SSE-Ol 

2.00E+OO 2.4SE-03 1. SOE-Ol 9.S9E-03 2. 32E-Ol 4.2SE-Ol 

3.00E+OO 2.43E-03 1.6SE-Ol 1.70E-03 1.2SE-Ol 2. 94E-Ol 

4.00E+OO 2.4lE-03 1. 57E-Ol 3.00E-04 6.07E-02 2.20E-Ol 

5.00E+OO 2.40E-03 1. 53E-Ol 5.30E-05 2.S5E-02 1. S4E-Ql 

6.00E+OO 2.3SE-03 1.5lE-Ol 9. 37E-06 1.34E-02 1. 66E-Ol 

7.00E+OO 2. 37E-03 1. 49E-Ol 1. 66E-06 6. 43E-03 1.5SE-Ol 

8.00E+OO 2. 35E-03 1.49E-Ol 2. 93E-07 3.lSE-03 1.54E-Ol 

9.00E+OO 2. 34E-03 1.48E-Ol S.17E-OS 1. 65E-03 1. 52E-Ol 

1.OOE+Ol 2. 33E-03 1.48E-Ol O.OOE+OO 9.20E-04 1.5lE-Ol 

2.00E+Ol 2. 27E-03 1. 46E-Ol O.OOE+OO 2. 36E-04 1.49E-Ol 

3.00E+Ol 2. 27E-03 1.45E-Ol O.OOE+OO 2.32E-04 1.47E-Ol 

4.00E+Ol 2.30E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1. 46E-Ol 

5.00E+Ol 2. 34E-03 1.42E-Ol O.OOE+OO 2.26E-04 1.45E-Ol 

6.00E+Ol 2. 39E-03 1.4lE-Ol O.OOE+OO 2. 23E-04 1.43E-Ol 

7.00E+Ol 2. 45E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.42E-Ol 

8.00E+Ol 2.51E-03 1. 38E-Ol O.OOE+OO 2.l7E-04 1.40E-Ol 

9.00E+Ol 2.5SE-03 1.36E-Ol O.OOE+OO 2. 14E-04 1. 39E-Ol 

1.OOE+02 2. 64E-03 1.3SE-Ol O.OOE+OO 2.11E-04 1.3SE-Ol 

2.00E+02 3. 33E-03 1.22E-Ol O.OOE+OO 1.83E-04 1.25E-Ol 

3.00E+02 4.06E-03 l.lOE-OI O.OOE+OO 1.60E-04 1.14E-Ol 

4.00E+02 4.79E-03 9.98E-02 O.OOE+OO 1.39E-04 1.OSE-Ol 

5.00E+02 5.S2E-03 9.06E-02 O.OOE+OO 1.2lE-04 9. 62E-02 

6.00E+02 6. 23E-03 S.23E-02 O.OOE+OO 1.05E-04 8. 86E-02 

7.00E+02 6. 93E-03 7.49E-02 O.OOE+OO 9.l7E-OS S.19E-02 

8.00E+02 7.6lE-03 6. 83E-02 O.OOE+OO 7.9SE-05 7.60E-02 

9.00E+02 S.27E-03 6. 23E-02 O.OOE+OO 6.9SE-OS 7.07E-02 

1.OOE+03 S.90E-03 S.70E-02 O.OOE+OO 6.05E-OS 6.60E-02 

2.00E+03 1.3SE-02 2.SSE-02 O.OOE+OO 1.SlE-05 3. 93E-02 

3.00E+03 1. 64E-02 1. 34E-02 O.OOE+OO 3.7SE-06 2.9SE-02 

4.00E+03 1.77E-02 8. 25E-03 O.OOE+OO 9. 45E-07 2.59E-02 

S.OOE+03 1.SlE-02 S.9lE-03 O.OOE+OO 2.36E-07 2.40E-02 

7.00E+03 1.SlE-02 4. 27E-03 O.OOE+OO 1. 48E-08 2. 23E-02 

S.OOE+03 1.7SE-02 4.00E-03 O.OOE+OO O.OOE+OO 2.lSE-02 

9.00E+03 1.7SE-02 3. 87E-03 O.OOE+OO O.OOE+OO 2.l4E-02 

1.OOE+04 1. 72E-02 3. SOE-03 O.OOE+OO O.OOE+OO 2.10E-02 

2.00E+04 1. 43E-02 3. 73E-03 O.OOE+OO O.OOE+OO 1.80E-Q2 

B-449 
CLASS Y AKAD = 1 MICRON HALFLIFE= 1.20£+07 DAYS PROTACTINIUK 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -~----------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3. 56E-04 1.04E-05 

2.00E-Ol 6. 82E-04 2.10E-04 

3.00E-Ol 9. 38E-04 1.06E-03 

4.00E-Ol 1.14E-03 3.07E-03 

5.00E-Ol 1. 29E-03 6.66E-03 

6.00E-OI 1.42E-03 1.21E-02 

7.00E-Ol 1.52E-03 1. 94E-02 

8.00E-Ol 1.60E-03 2. 86E-02 

9.00E-01 1.66E-03 3. 96E-02 

1.OOE+OO 1.7lE-03 1.7lE-03 5.21E-02 S.21E-02 

2.00E+OO 2.30E-04 1.94E-03 1.61E-Ol 2. 13E-Ol 

3.00E+OO 8.00E-OS 2.02E-03 1.31E-Ol 3. 43E-Ol 

4.00E+OO S.70E-05 2.08E-03 7. 36E-02 4.17E-01 

5.00E+OO 5.04E-OS 2. 13E-03 3. 64E-02 4.S3E-01 

6.00E+OO 4. 72E-05 2.18E-03 1.72E-02 4.71E-Ol 

7.00E+OO 4.50E-05 2. 22E-03 8.12E-03 4.79E-01 

8.00E+OO 4. 33E-OS 2.27E-03 3. 88E-03 4. 83E-Ol 

9.00E+OO 4. 18E-05 2.31E-03 1.91E-03 4. 85E-Ol 

1.00E+01 4.05E-OS 2.35E-03 9.8SE-04 4. 86E-01 

2.00E+Ol 3.18E-OS 2.70E-03 1.3SE-04 4. 88E-Ol 

3.00E+Ol 2.73E-OS 2. 99E-03 1. 33E-04 4. 89E-Ol 

4.00E+Ol 2. 49E-05 3.2SE-03 1.31E-04 4.90E-01 

5.00E+Ol 2.3SE-OS 3. 49E-03 1.29E-04 4.92E-Ol 

6.00E+Ol 2. 26E-OS 3. 72E-03 1. 27E-04 4. 93E-Ol 

7.00E+Ol 2.21E-05 3. 94E-03 1.26E-04 4. 94E-Ol 

8.00E+Ol 2.17E-05 4.16E-03 1. 24E-04 4. 95E-Ol 

9.00E+0l 2. 14E-OS 4.38E-03 1.22E-04 4.97E-Ol 

1.OOE+02 2.llE-OS 4. 59E-03 1.21E-04 4. 98E-Ol 

2.00E+02 1.97E-OS 6. 62E-03 1.05E-04 5.09E-Ol 

3.00E+02 1. 92E-05 8. 56E-03 9. 14E-05 5.19E-Ol 

4.00E+02 1. 88E-05 1.OSE-02 7.9SE-OS S.27E-Ol 

S.OOE+02 1. 86E-05 1.23E-02 6. 93E-05 S.3SE-01 

7.00E+02 1. 79E-05 1.60E-02 S.2SE-OS S.47E-Ol 

8.00E+02 1. 74E-05 1.77E-02 4.S7E-OS S.52E-Ol 

9.00E+02 1. 69E-OS 1.95E-02 3.98E-OS S.56E-Ol 

1.OOE+03 1. 64E-OS 2.llE-02 3. 46E-OS S.60E-Ol 

2.00E+03 1.02E-OS 3. 44E-02 8.66E-06 5. 79E-Ol 

3.00E+03 5.61E-06 4.21E-02 2. 16E-06 5.83E-01 

4.00E+03 2. 93E-06 4. 62E-02 S.41E-07 5. 84E-Ol 

5.00E+03 1.SOE-06 4. 84E-02 1.3SE-07 S.8SE-01 

7.00E+03 3.80E-07 5.00E-02 O.OOE+OO 5.8SE-Ol 

8.00E+03 1.91E-07 5.03E-02 O.OOE+OO S.8SE-Ol 

9.00E+03 9.S4E-08 S.04E-02 O.OOE+OO S.8SE-Ol 

1.00E+04 4.77E-08 5.0SE-02 O.OOE+OO S.84E-Ol 

B-4S0 
CLASS Y AHA» "" 1 KIeRON HALFLlFE= 2.57E+ll DAYS URANIUM. 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------~---------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 54E-03 3.04E-Ol 2.5SE-Ol 7.30E-02 6. 39E-Ol 

2.00E-Ol 3. 24E-03 2.S5E-Ol 2.l7E-Ol 1. 33E-Ol 6.3SE-Ol 

3.00E-Ol 3.02E-03 2.70E-0l 1. S2E-Ol 1. S2E-Ol 6. 37E-Ol 

4. OOE-O 1 2.S6E-03 2.S7E-Ol 1. 53E-Ol 2. 21E-ol 6. 35E-Ol 

5.00E-Ol 2.73K-03 2. 47E-Ol 1.29E-Ol 2. S2E-Ol 6.3lE-OI 

6.00E-Ol 2. 63E-03 2.3SE-Ol 1.OSE-Ol 2. 76E-Ol 6.2SE-Ol 

7.00E-Ol 2.S4E-03 2.3lE-Ol 9.l2E-02 2. 93E-Ol 6.1SE-Ol 

S.OOE-Ol 2. 46E-03 2. 24E-Ol 7. 67E-02 3.05E-Ol 6.09E-Ol 

9.00E-Ol 2.40E-03 2.l9E-Ol 6. 45E-02 3.l2E-0l 5. 97E-Ol 

1.OOE+OO 2. 34E-03 2.l3E-Ol 5. 42E-02 3.l5E-Ol S.S5E-Ol 

2.00E+OO 2.02E-03 1. SOE-Ol 9.59E-03 2. 32E-Ol 4.24E-Ol 

3.00E+OO 1.S7E-03 1. 65E-Ol 1.70E-03 1.2SE-Ol 2. 93E-Ol 

4.00E+OO 1. 76E-03 1.S7E-Ol 3.00E-04 6.06E-02 2.l9E-Ol 

5.00E+OO 1. 65E-03 1. 53E-Ol S.30E-OS 2.SSE-02 1.S3E-Ol 

6.00E+OO 1.S6E-03 1. SlE-Ol 9.37E-06 1. 34E-02 1. 66E-Ol 

7.00E+OO 1. 47E-03 1. 49E-Ol 1. 66E-06 6. 42E-03 1. S7E-Ol 

S.OOE+OO 1.39E-03 1. 49E-Ol 2. 93E-07 3.l7E-03 1.S3E-Ol 

9.00E+OO 1. 32E-03 1.4SE-OI S.17E-OS 1. 64E-03 1.SlE-Ol 

1.OOE+Ol 1.2SE-03 1.4SE-0l O.OOE+OO 9.l9E-04 1.50E-OI 

2.00E+Ol S.23E-04 1. 46E-Ol O.OOE+OO 2. 36E-04 1.4SE-Ol 

3.00E+Ol 6.20E-04 1.4SE-Ol O.OOE+OO 2.32E-04 1.46E-Ol 

4.00E+Ol S.OSE-04 1. 43E-Ol O.OOE+OO 2. 29E-04 1.44E-Ol 

S.OOE+Ol 4.40E-04 1.42E-OI O.OOE+OO 2. 26E-04 1.43E-Ol 

6.00E+Ol 3. 97E-04 1.41E-OI O.OOE+OO 2. 23E-04 1.4lE-Ol 

7.00E+Ol 3. 69E-04 1. 39E-Ol O.OOE+OO 2.l9E-04 1.40E-Ol 

S.OOE+Ol 3. SOE-04 1.3SE~Ol O.OOE+OO 2.l6E-04 1.3SE-Ol 

9.00E+Ol 3.3SE-04 1.36E-Ol O.OOE+OO 2.13E-04 1.37E-Ol 

1.OOE+02 3. 32E-04 1. 35E-Ol O.OOE+OO 2.l1E-04 1. 35E-Ol 

2.00E+02 3.S0E-04 1. 22E-Ol O.OOE+OO 1. S3E-04 1. 22E-Ol 

3.00E+02 3. 92E-04 1.lOE-Ol O.OOE+OO 1.60E-04 1.llE-0l 

4.00E+02 4.33E-04 9.9SE-02 O.OOE+OO 1. 39E-04 1.OOE-Ol 

5.00E+02 4.71E-04 9.06E-02 O.OOE+OO 1. 21E-04 9.l2E-02 

6.00E+02 5.0SE-04 S.23E-02 O.OOE+OO 1.OSE-04 S.29E-02 

7.00E+02 5. 42E-04 7.49E-02 O.OOE+OO 9. 16E-OS 7.SSE-02 

S.OOE+02 5.74E-04 6.S3E-02 O.OOE+OO 7.9SE-OS 6.S9E-02 

9.00E+02 6.03E-04 6. 23E-02 O.OOE+OO 6. 94E-OS 6.30E-02 ! ,,' 1.00E+03 6.30E-04 5.70E-02 O.OOE+OO 6.0SE-OS S.77E-02 

2.00E+03 7. 97E-04 2.SSE-02 O.OOE+OO I.SlE-OS 2. 63E-02 

3.00E+03 S.27E-04 1. 34E-02 O.OOE+OO 3.7SE-06 1. 42E-02 

4.00E+03 7.S7E-04 S.2SE-03 O.OOE+OO 9.4SE-07 9.04E-03 

S.OOE+03 7.lSE-04 5. 92E-03 O.OOE+OO 2.36E-07 6. 63E-03 

7.00E+03 S.66E-04 4. 27E-03 O.OOE+OO 1.4SE-OS 4.S3E-03 

S.OOE+03 4.96E-04 4.00E-03 O.OOE+OO O.OOE+OO 4. SOE-03 

9.00E+03 4. 33E-04 3.S7E-03 O.OOE+OO O.OOE+OO 4.30E-03 

1.OOE+04 3.7SE-04 3.S0E-03 O.OOE+OO O.OOE+OO 4.lSE-03 

2.00E+04 9.44E-OS 3. 74E-03 O.OOE+OO O.OOE+OO 3.S3E-03 

B-45l 
CLASS Y AMAD - 1 MICRON BALFLIFE= 2.57£+11 DAYS URANIUM 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.80E-04 l.04E-05 

2.00E-Ol 7.49E-04 2.l0E-04 

3.00E-Ol 1.05E-OJ 1.06E-03 

4. OOE-O 1 1.3IE-03 3.07E-03 

5.00E-Ol I. 53E-03 6. 66E-03 

6.00E-Ol 1.7lE-03 l.2lE-02 

7.00E-Ol I. 87E-03 1. 94E-02 

8.00E-Ol 2.0lE-03 2. 86E-02 

9.00E-Ol 2.l3E-03 3. 95E-02 

l.OOE+OO 2. 23E-03 2.23E-03 S.20E-02 5.20E-02 

2.00E+OO S.49E-04 2. 78E-03 1.60E-Ol 2.l3E-Ol 

3.00E+OO 2.30E-04 3.0lE-03 1.31E-Ol 3. 43E-Ol 

4.00E+OO 1.57E-04 3.l7E-OJ 7. 35E-02 4. 17E-Ol 

5.00E+OO 1.31E-04 3.30E-03 3. 63E-02 4.S3E-Ol 

6.00E+OO 1.17E-04 3.41E-03 1.72E-02 4.70E-Ol 

7.00E+OO 1.07E-04 3. 52E-03 8.1lE-03 4. 78E-Ol 

8.00E+OO 9.81E-05 3. 62E-03 3.88E-03 4.82E-0l 

9.00E+OO 9.07E-05 3.71E-03 1.9lE-03 4. 84E-Ol 

1.OOE+Ol 8. 42E-05 3.79E-03 9.83E-04 4.8SE-Ol 

2.00E+Ol 4. 69E-OS 4.40E-03 I. 35E-04 4. 87E-Ol 

3.00E+Ol 3. 27E-05 4. 78E-03 1.33E-04 4.89E-Ol 

4.00E+Ol 2.6SE-05 5.07E-03 1.31E-04 4.90E-OI 

5.001i:+Ol 2. 34E-05 5.32E-03 1.29E-04 4.9lE-OI 

7.00E+Ol 2.04E-OS 5. 75E-03 1.26E-04 4. 94E-OI 

8.00E+Ol 1. 96E-OS 5.95E-03 1.24E-04 4.9SE-Ol 

9.00E+OI 1.9lE-05 6.14E-03 1. 22E-04 4. 96E-OI 

1.OOE+02 1.87E-OS 6. 33E-03 1.20E-04 4. 97E-OI 

2.00E+02 1.8IE-05 8.1SE-03 I.OSE-04 5.09E-Ol 

3.00E+02 1. 83E-OS 9. 97E-03 9.l3E-05 5.lBE-Ol 

4.00E+02 1. 82E-OS 1.18E-02 7. 95E-OS 5.27E-Ol 

5.00E+02 1.81E-05 1.36E-02 6. 92E-05 5. 34E-Ol 

7.00E+02 I. 74E-05 I. 72E-02 5. 24E-05 5. 46E-ol 

8.00E+02 1.69E-05 1. 89E-02 4. 56E-05 5.51E-Ol 

9.00E+02 1.64E-05 2.05E-02 3. 97E-05 5. 56E-Ol 

1.OOE+03 I.SBE-05 2.21E-02 3.46E-05 S.59E-Ol 

2.00E+03 9. 76E-06 3. 49E-02 8. 65E-06 5.7BE-Ol 

3.00E+03 5. 39E-06 4. 23E-02 2.l6E-06 5. 83E-Ol .. ' 4.00E+03 2. 86E-06 4. 63E-02 5.40E-07 5. 84E-Ol 

5.00E+03 1.50E-06 4.B4E-02 1. 35E-07 5. 84E-OI 

7.00E+03 4.36E-07 5.01E-02 O .. OOE+OO 5.B4E-Ol 

8.00E+03 2. 48E-07 5.04E-02 O.OOE+OO 5. 84E-OI 

9.00E+03 I.SOE-07 5.06E-02 O.O()E+OO 5. 84E-Ol 

1.OOE+04 9. 75E-08 5.07E-02 O.OOE+OO 5. 84E-Ol 

2.00E+04 1.3lE-08 5.l1E-02 O.OOE+OO 5. 84E"':'OI 

B-4S2 
CLASS Y AMAD = 1 MICRON HALFLIFE= 1.16E+12 DAYS URANIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------~--------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3. 54E-03 3.04E-01 2. 58E-01 7.30E-02 6. 39E-01 

2.00E-01 3. 24E-03 2. 85E-01 2. 17E-01 1. 33E-01 6. 38E-01 

3.00E-01 3.02E-03 2.70E-01 1.82E-01 1.82E-01 6.37E-01 

4.00E-01 2. 86E-03 2. 57E-01 1.53E-01 2.21E-01 6.35E-01 

5.00E-01 2. 73E-03 2. 47E-01 1. 29E-01 2.52E-01 6.31E-01 

6.00E-01 2. 63E-03 2. 38E-01 1.08E-01 2. 76E-01 6. 25E-Ol 

7.00E-01 2. 54E-03 2. 31E-01 9. 12E-02 2. 93E-01 6. 18E-01 

8.00E-01 2. 46E-03 2. 24E-Ol 7. 67E-02 3.05E-01 6.09E-01 

9.00E-01 2.40E-03 2. 19E-01 6. 45E-02 3. 12E-01 5. 97E-01 

1.00E+OO 2. 34E-03 2. 13E-01 5.42E-02 3. 15E-01 5. 85E-01 

2.00E+00 2.02E-03 1.80E-01 9.59E-03 2.32E-01 4.24E-01 

3.00E+00 1. 87E-03 1.65E-01 1.70E-03 1. 25E-Ol 2. 93E-Ol 

4.00E+00 1. 76E-03 1.57E-01 3.00E-04 6.06E-02 2. 19E-01 

5.00E+00 1.65E-03 1. 53E-01 5.30E-05 2. 85E-02 1.83E-01 

6.00E+00 1.56E-03 1. 51E-01 9.37E-06 1.34E-02 1. 66E-01 

7.00E+00 1. 47E-03 1. 49E-01 1. 66E-06 6. 42E-03 1. 57E-01 

8.00E+00 1.39E-03 1. 49E-01 2. 93E-07 3. 17E-03 1.53E-01 

9.00E+00 1. 32E-03 1. 48E-01 5. 17E-08 1. 64E-03 1.5lE:-01 

1.00E+Ol 1. 25E-03 1.48E-01 O.OOE+OO 9. 19E-04 1.50E-01 

2.00E+Ol 8. 23E-04 1. 46E-01 O.OOE+OO 2. 36E-04 1.48E-Ol 

3.00E+Ol 6.20E-04 1. 45E-01 O.OOE+OO 2. 32E-04 1.46E-Ol 

4.00E+Ol 5.08E-04 1. 43E-01 O.OOE+OO 2. 29E-04 1. 44E-01 

5.00E+01 4.40E-04 1. 42E-01 O.OOE+OO 2. 26E-04 1. 43E-01 

6.00E+Ol 3. 97E-04 1.41E-01 O.OOE+OO 2. 23E-04 1.41E-Ol 

7.00E+01 3.69E-04 1. 39E-01 O.OOE+OO 2. 19E-04 1.40E-01 

8.00E+01 3.50E-04 1. 38E-01 O.OOE+OO 2. 16E-04 1. 38E-01 

9.00E+01 3. 38E-04 1. 36E-01 O.OOE+OO 2. 13E-04 1.37E-01 

1.00E+02 3. 32E-04 1. 35E-01 O.OOE+OO 2. l1E-04 1. 35E-01 

2.00E+02 3.50E-04 1. 22E-01 O.OOE+OO 1. 83E-04 1. 22E-01 

3.00E+02 3. 92E-04 1.10E-01 O.OOE+OO 1.60E-04 1. l1E-Ol 

4.00E+02 4.33E-04 9. 98E-02 O.OOE+OO 1.39E-04 1.00E-01 

5.00E+02 4. 71E-04 9.06E-02 O.OOE+OO 1. 21E-04 9. 12E-02 

6.00E+02 5.08E-04 8. 23E-02 O.OOE+OO 1.05E-04 8. 29E-02 

7.00E+02 5. 42E-04 7.49E-02 O.OOE+OO 9. 16E-05 7. 55E-02 

8.00E+02 5.74E-04 6.83E-02 O.OOE+OO 7. 98E-05 6. 89E-02 

9.00E+02 6.03E-04 6. 23E-02 O.OOE+OO 6. 94E-05 6.30E-02 

1.00E+03 6.30E-04 5.70E-02 O.OOE+OO 6.05E-05 5.77E-02 

2.00E+03 7. 97E-04 2. 55E-02 O.OOE+OO 1. 51E-05 2. 63E-02 

3.00E+03 8. 27E-04 1. 34E-02 O.OOE+OO 3.78E-06 1.42E-02 

4.00E+03 7. 87E-04 8. 25E-03 O.OOE+OO 9.45E-07 9.04E-03 

5.00E+03 7.18E-04 5.92E-03 O.OOE+OO 2. 36E-07 6. 63E-03 

7.00E+03 5. 66E-04 4. 27E-03 O.OOE+OO 1. 48E-08 4. 83E-03 

8.00E+03 4.96E-04 4.00E-03 O.OOE+OO O.OOE+OO 4.50E-03 

9.00E+03 4. 33E-04 3. 87E-03 O.OOE+OO O.OOE+OO 4.30E-03 

1.00E+04 3.78E-04 3.80E-03 O.OOE+OO O.OOE+OO 4. 18E-03 

2.00E+04 9. 44E-05 3. 74E-03 O.OOE+OO O.OOE+OO 3. 83E-03 

B-453 
CLASS Y AHAD - 1 HICltON HALFLIFE= 1.16E+12 DAYS URANIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.80E-04 1.04E-OS 

2.00E-Ol 7.49E-04 2.l0E-04 

3.00E-Ol I.OSE-03 1.06E-03 

4.00E-Ol I.3lE-03 3.07E-03 

S.OOE-OI I.S3E-03 6. 66E-03 

6.00E-OI 1.71E-03 1.2lE-Q2 

7.00E-OI 1.87E-03 1. 94E-02 

8.00E-Ol 2.0IE-03 2. 86E-02 

9.00E-OI 2.13E-03 3.9SE-02 

1.OOE+OO 2. 23E-03 2.23E-03 S.20E-02 S.20E-02 

2.00E+OO S.49E-04 2. 78E-03 1.60E-Ol 2.13E-Ol 

3.00E+OO 2.30E-04 3.0lE-03 1.3lE-Ol 3. 43E-Ol 

4.00E+OO I.57E-04 3.17E-03 7.3SE-02 4.17E-Ol 

5.00E+OO 1.3IE-04 3.30E-03 3. 63E-02 4.S3E-OI 

6.00E+OO I.I7E-04 3.4lE-03 1.72E-02 4.70E-Ol 

7.00E+OO 1.07E-04 3.S2E-03 8.11E-03 4. 78E-Ol 

8.00E+OO 9.8lE-05 3. 62E-03 3. 88E-03 4. 82E-Ol 

9.00E+OO 9.07E-OS 3.71E-03 1.9IE-03 4. 84E-Ol 

1.OOE+0l 8.42E-OS 3. 79E-03 9. 83E-04 4. 85E-Ol 

2.00E+OI 4. 69E-OS 4.40E-03 1.3SE-04 4. 87E-OI 

3.00E+Ol 3. 27E-OS 4. 78E-03 1.33E-04 4. 89E-Ol 

4.00E+Ol 2.6SE-05 S.07E-03 1.3lE-04 4.90E-OI 

S.OOE+OI 2. 34E-05 S.32E-03 1. 29E-04 4.9IE-OI 

7.00E+OI 2.04E-OS S.7SE-03 1. 26E-04 4. 94E-OI 

8.00E+OI I.96E-05 S.95E-03 1. 24E-04 4.9SE-Ol 

9.00E+OI I.9lE-OS 6.l4E-03 1. 22E-04 4. 96E"'Ol 

1.OOE+02 1. 87E-OS 6. 33E-03 1.20E-04 4. 97E-OI 

2.00E+02 1.8lE-05 8.l5E-03 1.OSE-04 5.09E-Ol 

3.00E+02 1.83E-OS 9. 97E-03 9.l3E-OS 5.l8E-OI 

4.00E+02 1. 82E-OS 1.18E-02 7.9SE-OS 5. 27E-OI 

5.00E+02 1.8lE-05 1. 36E-02 6. 92E-OS S.34E-Ol 

7.00E+02 1. 74E-OS 1.72E-02 5. 24E-05 5. 46E-OI 

8.00E+02 1. 69E-05 1.89E-02 4.S6E-05 5.SlE-OI 

9~OOE+02 1.64E-05 2.0SE-02 3. 97E-05 5. 56E-Ol 

I.OOE+03 I.58E-05 2.2IE-02 3. 46E-OS 5. 59E-Ol 

2.00E+03 9. 76E-06 3.49E-02 8.6SE-06 5. 78E-Ol 

3.00E+03 S.39E-06 4. 23E-02 2.l6E-06 5. 83E-OI 

4.00E+03 2. 86E-Q6 4. 63E-02 S.40E-07 5.84E-OI 

S.OOE+03 1.SOE-06 4. 84E-02 1.3SE-07 5.84E-OI 

7.00E+03 4. 36E-07 S.OlE-02 O.OOE+OO 5. 84E-OI 

8.00E+03 2.48E-07 S.04E-02 O.OOE+OO 5. 84E-Ol 

9.00E+03 1.SOE-07 S.06E-02 O.OOE+OO 5. 84E-Ol 

I.OOE+04 9.75E-08 5.07E-02 O.OOE+OO 5. 84E-Ol 

2.00E+04 1.3lE-08 5.llE-02 O.OOE+OO 5. 84E-Ol 

B-454 
CLASS Y AHAD- 1 MICRON HALFLIFE= 3.20£+04 DAYS PLUTONIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------~----------~-------------------~-~--------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.B9E-03 3.04E-Ol 2.SBE-OI 7.31E-02 6. 39E-01 

2.00E-01 3.90E-03 2.8SE-01 2.17E-01 l.33E-Ol 6. 39E-01 

3.00E-01 3.90E-03 2.70E-01 1.82E-01 1.82E-Ol 6.38E-01 

4.00E-01 3. 89E-03 2.S7E-01 1.S3E-01 2.21E-01 6.36E-Ol 

S.OOE-01 3. 89E-03 2.47E-01 1.29E-01 2.S2E-0l 6.32E-0l 

6.00E-01 .3.89E-03 2.38E-01 1.0BE-01 2. 76E-01 6.27E-01 

7.00E-01 3. 89E-03 2.31E-01 9. 12E-02 2. 94E-01 6.20E-OI 

8.00E-Ol 3.B9E-03 2. 24E-01 7. 67E-02 3.06E-01 6.lOE-Ol 

9.00E-01 3. 89E-03 2. 19E-01 6.4SE-02 3. 13E-01 S.99E-01 

1.00E+OO 3. 89E-03 2. 13E-01 S.42E-02 3. 16E-01 5. 87E-01 

2.00E+OO 3. 89E-03 1.80E-01 9.S9E-03 2.32E-01 4. 26E-01 

3.00E+OO 3.90E-03 1.65E-Ol 1.70E-03 1.2SE-Ol 2.9SE-Ol 

4.00E+OO 3.91E-03 1. S7E-0l 3.00E-04 6.07E-02 2. 22E-01 

S.OOE+OO 3. 92E-03 1.S3E-Ol 5.30E-OS 2. 86E-02 1.8SE-Ol 

6.00E+OO 3.93E-03 1.S1E-01 9. 36E-06 1.34E-02 1.68E-Ol 

7.00E+OO 3.9SE-03 1.49E-01 1. 66E-06 6. 44E-03 1.60E-01 

8.00E+OO 3.96E-03 1.49E-01 2.93E-07 3. 18E-03 1.56E-Ol 

9.00E+OO 3. 98E-03 1. 48E-Ol S.l7E-08 1.6SE-03 1.S4E-Ol 

1.00E+0l 3. 99E-03 1.48E-Ol O.OOE+OO 9.20E-04 1.S3E-Ol 

2.00E+01 4.14E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1.S1E-Ol 

3.00E+01 4.30E-03 1.4SE-Ol O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+Ol 4.46E-03 1.43E-01 O.OOE+OO 2. 29E-04 1. 48E-01 

S.OOE+Ol 4.62E-03 1. 42E-Ol O.OOE+OO 2.26E-04 1.47E-Ol 

6.00E+Ol 4. 78E-03 1.40E-01 O.OOE+OO 2. 23E-04 1.4SE-Ol 

7.00E+Ol 4. 94E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+01 S.llE-03 1.37E-Ol O.OOE+OO 2. 16E-04 1.43E-01 

9.00E+Ol S.27E-03 1. 36E-Ol O.OOE+OO 2.13E-04 1.41E-01 

1.00E+02 S.44E-03 1.3SE-01 O.OOE+OO 2.lOE-04 1.40E-Ol 

2.00E+02 7.10E-03 1.21E-Ol O.OOE+OO 1.83E-04 1.29E-Ol 

3.00E+02 B.78E-03 1.09E-Ol O.OOE+OO 1.S9E-04 1. 18E-Ol 

4.00E+02 1.04E-02 9.90E-02 O.OOE+OO 1.38E-04 1.lOE-Ol 

S.OOE+02 1.21E-02 8. 96E-02 O.OOE+OO 1.20E-04 1.02E-Ol 

6.00E+02 1.37E-02 8.12E-02 O.OOE+OO 1.04E-04 9.S0E-02 

7.00E+02 1.S3E-02 7. 38E-02 O.OOE+OO 9.04E-05 8.91E-02 

8.00E+02 1. 68E-02 6.71E-02 O.OOE+OO 7. 86E-OS 8.40E-02 

9 .. 00E+02 1. 82E-02 6. llE-02 O.OOE+OO 6. 82E-05 7. 94E-02 

1.00E+03 . 1.96E-02 S.SBE-02 O.OOE+OO 5. 93E-OS 7.S5E-02 

2.00E+03 2. 99E-02 2. 44E-02 O.OOE+OO 1.45E-OS S.43E-02 

3.00E+03 3. 48E-02 1.2SE-02 O.OOE+OO 3.5SE-06 4. 73E-02 

4.00E+03 3. 64E-02 7. 56E-03 O.OOE+OO 8.68E-07 4.39E-02' 

5.00E+03 3. 63E-02 5.31E-03 O.OOE+OO 2.12E-07 4. 16E-02 

7.00E+03 3.40E-02 3. 67E-03 O.OOE+OO 1.27E-08 3.77E-02 

8.00E+03 3.2SE-02 3. 37E-03 O.OOE+OO O.OOE+OO 3.59E-02 

9.00E+03 3.10E-02 3. 18E-03 O.OOE+OO O.OOE+OO 3. 42E-02 

1.OOE+04 2. 96E-02 3.06E-03 O.OOE+OO O.OOE+OO 3.26E-02 

2.00E+04 1.80E-02 2.42E-03 O.OOE+OO O.OOE+OO 2.04E-02 

.B-4SS 

i 

I. 
CLASS Y AMAD = 1 MICRON HALFLIFE= 3.20£+04 DAYS PLUTONIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----....... --------------''-,-..... -------------------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.6BE-06 1.19E-05 

2.00E-Ol 3. 55E-06 2.13E-04 

3.00E-Ol 5. 32E-06 1.06E-03 

4.00E-Ol 7.01E-06 3.0BE-03 

5.00E-OI B.6IE-06 6. 67E-03 

6.00E-OI I.OlE-05 1.2IE-02 

7.00E-Ol I. 16E-05 1.94E-02 

B.OOE-Ol 1.30E-05 2.B6E-02 

9.00E-Ol 1.43E-05 3. 96E-02 

1.00E+OO 1. 55E-05 1.5SE-OS 5.2IE-02 S.21E-02 

2.00E+OO 9. 64E-06 2.S2E-05 1.61E-OI 2.13E-Ol 

3.00E+OO 6.09E-06 3.12E-OS 1.31E-Ol 3. 44E-Ol 

4.00E+OO 4.05E-06 3.S3E-05 7.36E-02 4.17E-Ol 

S.OOE+OO 2.B7E-06 3.B2E-05 3. 64E-02 4. 54E-Ol 

6.00E+OO 2.1BE-06 4.03E-OS 1.73E-02 4.71E-Ol 

7.00E+OO 1.7BE-06 4.2IE-OS B.13E-03 4. 79E-OI 

B.OOE+OO 1.S3E-06 4. 36E-OS 3.B9E-03 4.B3E-OI 

9.00E+OO 1.3BE-06 4.S0E-05 1.9IE-03 4.B5E-Ol 

I.OOE+OI 1.29E-06 4. 63E-OS 9.B7E-04 4.B6E-OI 

2.00E+Ol 1.00E-06 5.73E-OS 1. 36E-04 4.BBE-OI 

3.00E+OI B.BOE-07 6.6SE-OS 1. 34E-04 4.B9E-Ol 

4.00E+OI B.04E-07 7.49E-OS 1. 32E-04 4.90E-Ol 

S.OOE+OI 7.S6E-07 B.26E-OS 1.30E-04 4. 92E-Ol 

6.00E+Ol 7.27E-07 9.00E-OS 1.2BE-04 4. 93E-Ol 

7.00E+OI 7.11E-07 9. 72E-OS 1.26E-04 4.94E-Ol 

B.OOE+OI 7.02E-07 1.04E-04 1. 24E-04 4.9SE-Ol 

9.00E+Ol 6.9BE-07 1.llE-04 1. 23E-04 4. 96E-Ol 

1.OOE+02 6.97E-·07 1.1BE-04 1.21E-04 4. 97E-Ol 

2.00E+02 7. 34E-07 1. B9E-04 1.OSE-04 S.OBE-Ol 

3.00E+02 7.7SE-07 2. 64E-04 9. 15E-OS S.16E-Ol 

4.00E+02 B.OBE-07 3. 43E-04 7. 96E-05 S.24E-Ol 

S.OOE+02 B.36E-07 4. 24E-04 6. 93E-OS S.30E-Ol 

6.00E+02 B. S7E-07 S.OBE-04 6.03E-05 S.3SE-Ol 

7.00E+02 B.73E-07 S.93E-04 S.25E-OS 5.40E-01 

8.00E+02 B.B4E-07 6. BOE-04 4. S7E-05 S.44E-Ol 

9.00E+02 B.92E-07 7. 67E-04 3.9BE-OS 5.47E-Ol 

1.OOE+03 B.96E-07 B.5SE-04 3.47E-OS S.49E-Ol , . 2.00E+03 B.36E-07 1.70E-03 9.01E-06 S.56E-Ol 

3.00E+03 7.39E-07 2. 44E-03 2. 66E-06 S.49E-Ol 

4.00E+03 6. 64E-07 3.0BE-03 1.06E-06 S.39E-Ol 

S.OOE+03 6.09E-07 3. 64E-03 6.40E-07 S.2BE-Ol 

7.00E+03 S.34E-07 4.60E-03 4. 62E-07 S.07E-Ol 

B.OOE+03 S.OSE-07 S.02E-03 4.32E-07 4. 97E-Ol 

9.00E+03 4. 79E-07 S.40E-03 4.09E-07 4. 86E-Ol 

1.OOE+04 4.S5E-07 5. 74E-03 3.8BE-07 4.76E-Ol 

2.00E+04 2. 75E-07 7. BIE-03 2. 35E-07 3. 86E-Ol 

B-4S6 
CLASS Y AHAD - 1 MICRON BA.LP'LlFE= 8.78E+06 DAYS PLUTONIUM 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------~----------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-01 3.89E-03 3.04E-0l 2.58E-0l 7.31E-02 6. 39E-Ol 

2.00E-Ol 3.90E-03 2. 85E-01 2. 17E-01 1. 33E-01 6. 39E-01 

3.00E-01 3.90E-03 2.70E-0l 1.82E-01 1. 82E-Ol 6. 38E-Ol 

4.00E-01 3.90E-03 2. 57E-01 1. 53E-01 2. 21E-01 6. 36E-01 

5.00E-Ol 3. 89E-03 2. 47E-01 1.29E-Ol 2.52E-01 6. 32E-Ol 

6.00E-Ol 3. 89E-03 2. 38E-Ol 1.08E-Ol 2. 76E-01 6. 27E-Ol 

7.00E-01 3. 89E-03 2.31E-01 9. 12E-02 2. 94E-Ol 6.20E-01 

8.00E-Ol 3.89E-03 2. 24E-Ol 7.67E-02 3.06E-01 6.10E-01 

9.00E-01 3. 89E-03 2. 19E-Ol 6.45E-02 3. 13E-Ol 6.00E-01 

1.00E+OO 3. 89E-03 2. 13E-01 S.42E-02 3.l6E-Ol 5. 87E-Ol 

2.00E+OO 3. 89E-03 1.80E-01 9. 59E-03 2.32E-01 4.26E-01 

3.00E+OO 3.90E-03 1. 65E-01 1.70E-03 1. 25E-01 2. 95E-01 

4.00E+OO 3.91E-03 1.57E-Ol 3.00E-04 6.07E-02 2. 22E-01 

5.00E+OO 3. 92E-03 1. 53E-01 S.30E-05 2. 86E-02 1.8SE-01 

6.00E+OO 3.93E-03 1. 51E-Ol 9.37E-06 1.35E-02 1. 68E-01 

7.00E+OO 3. 95E-03 1.49E-01 1. 66E-06 6. 44E-03 1.60E-01 

8.00E+OO 3. 96E-03 1.49E-01 2. 93E-07 3.l8E-03 1.56E-01 

9.00E+OO 3. 98E-03 1. 48E-01 5. 17E-08 1. 65E-03 1. 54E-Ol 

1.00E+Ol 3. 99E-03 1. 48E-01 O.OOE+OO 9.21E-04 1.53E-01 

2.00E+01 4. 15E-03 1. 46E-01 O.OOE+OO 2. 36E-04 1.51E-01 

3.00E+01 4.30E-03 1.45E-01 O.OOE+OO 2.32E-04 1.49E-01 

4.00E+01 4. 46E-03 1.43E-01 O.OOE+OO 2. 29E-04 1. 48E-01 

S.OOE+01 4.62E-03 1. 42E-01 O.OOE+OO 2.26E-04 1.47E-01 

6.00E+01 4. 79E-03 1.41E-Ol O.OOE+OO 2. 23E-04 1. 46E-01 

7.00E+Ol 4.95E-03 1.39E-01 O.OOE+OO 2.20E-04 1.44E-01 

8.00E+01 S.l2E-03 1. 38E-Ol O.OOE+OO 2. 17E-04 1. 43E-Ol 

9.00E+Ol S.28E-03 1.36E-01 O.OOE+OO 2. 14E-04 1.42E-Ol 

1.00E+02 S.4SE-03 1. 35E-01 O.OOE+OO 2. 11E-04 1.41E-Ol 

2.00E+02 7.13E-03 1.22E-0l O.OOE+OO 1.84E-04 1.29E-01 

3.00E+02 . 8.84E-03 1.lOE-Ol O.OOE+OO 1.60E-04 1. 19E-Ol 

4.00E+02 1.05E-02 9. 98E-02 O.OOE+OO 1.39E-04 1.10E-Ol 

5.00E+02 1. 22E-02 9.06E-02 O.OOE+OO 1. 21E .... 04 1.03E-01 

6.00E+02 1. 39E-02 8. 23E-02 O.OOE+OO 1.05E-04 9. 63E-02 

7.00E+02 1.5SE-02 7.49E-02 O.OOE+OO 9.l8E-OS 9.05E-02 

8.00E+02 1.71E-02 6. 83E-02 O.OOE+OO 7.99E-05 8. 54E-02 

9.00E+02 1.86E-02 6. 23E-02 O.OOE+OO 6. 96E-05 8.lOE-02 - . 1.00E+03 2.00E-02 5.70E-02 O.OOE+OO 6.06E-05 7.71E-02 

2.00E+03 3.l2E-02 2. 55E-02 O.OOE+OO 1.51E-05 5. 67E-02 

3.00E+03 3.71E-02 1. 34E-02 O.OOE+OO 3.78E-06 5.05E-02 

4.00E+03 3. 96E-02 8. 25E-03 O.OOE+OO 9. 46E-07 4. 79E-02 

5.00E+03 4.04E-02 5.91E-03 O.OOE+OO 2. 37E-07 4. 63E-02 

7.00E+03 3. 95E-02 4. 27E-03 O.OOE+OO 1. 48E-08 4. 38E-02 

8.00E+03 3. 87E-02 4.00E-03 O.OOE+OO O.OOE+OO 4.27E-02 

9.00E+03 3.77E-02 3. 87E-03 O.OOE+OO O.OOE+OO 4.l6E-02 

1.OOE+04 3. 67E-02 3.80E-03 O.OOE+OO O.OOE+OO 4.05E-02 

2.00E+04 2. 76E-02 3. 73E-03 O.OOE+OO O.OOE+OO 3.l4E-02 

B-457 
CLASS Y ·AMAD = 1 MICRON HALFLIFE= 8.78E+06 DAYS PLUTONIUM 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----~-----------~-----~~----~--~~-~-------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 1. 68E-06 1. 19E-05 

2.00E-01 3. 55E-06 2. 13E-04 

3.00E-01 5.32E-06 1.06E-03 

4.00E-01 7.01E-06 3.08E-03 

5.00E-01 8.61E-06 6. 67E-03 

6.00E-01 1.01E-05 1.21E-02 

7.00E-01 1. 16E-05 1.94E-02 

8.00E-01 1.30E-05 2. 86E-02 

9.00E-Ol 1.43E-05 3.96E-02 

1.00E+00 1.55E-05 1. SSE-OS 5. 21E-02 5.21E-02 

2.00E+00 9. 64E-06 2. 52E-05 1.61E-Ol 2.13E-01 

3.00E+00 6.09E-06 3. 12E-05 1.31E-01 3. 44E-Ol 

4.00E+00 4.05E-06 3. 53E-05 7.36E-02 4.17E-Ol 

5.00E+00 2.87E-06 3.82E-05 3. 64E-02 4. 54E-Ol 

6.00E+00 2. 18E-06 4.03E-05 1.73E-02 4.71E-01 

7.00E+00 1. 78E-06 4.21E-05 8. 13E-03 4. 79E-01 

8.00E+00 1. 53E-06 4. 37E-05 3.89E-03 4.83E-01 

9.00E+00 1. 38E-06 4.50E-05 1.91E-03 4.85E-Ol 

1.00E+01 1.29E-06 4. 63E-05 9. 87E-04 4. 86E-01 

2.00E+Ol 1.00E-06 5. 73E-05 1. 36E-04 4. 88E-Ol 

3.00E+Ol 8.81E-07 6. 66E-05 1.34E-04 4.90E-Ol 

4.00E+Ol 8.04E-07 7.49E-05 1. 32E-04 4.91E-Ol 

5.00E+Ol 7.57E-07 8. 27E-05 1.30E-04 4. 92E-Ol 

6.00E+Ol 7.28E-07 9.01E-05 1. 28E-04 4.93E-Ol 

7.00E+Ol 7. 12E-07 9.73E-05 1.26E-04 4. 95E-Ol 

8.00E+Ol 7.03E-07 1.04E-04 1. 25E-04 4.96E-Ol 

9.00E+01 6.99E-07 1. 11E-04 1.23E-04 4.97E-Ol 

1.00E+02 6. 99E-07 1. 18E-04 1.21E-04 4. 98E-Ol 

2.00E+02 7. 37E-07 1.90E-04 1.06E-04 5.10E-01 

3.00E+02 7.80E-07 2. 66E-04 9.21E-05 5.20E-Ol 

4.00E+02 8. 15E-07 3. 46E-04 8.03E-05 5. 28E-Ol 

5.00E+02 8.45E-07 4. 29E-04 7.00E-05 5. 36E-Ol 

6.00E+02 8. 68E-07 5. 14E-04 6. 11E-05 5.42E-Ol 

7.00E+02 8.86E-07 6.02E-04 5. 33E-05 5. 48E-Ol 

8.00E+02 9.00E-07 6. 92E-04 4. 65E-05 5.53E-Ol 

9.00E+02 9.09E-07 7. 82E-04 4.06E-05 5.57E-Ol 

1.00E+03 9. 15E-07 8. 73E-04 3.54E-05 5.61E-Ol 

2.00E+03 8. 72E-07 1. 78E-03 9.41E-06 5.81E-Ol 

3.00E+03 7.88E-07 2.61E-03 2.84E-06 5.86E-Ol 

4.00E+03 7. 23E-07 3. 36E-03 1. 16E-06 5.88E-01 

5.00E+03 6.78E-07 4.06E-03 7.13E-07 5.89E-Ol 

7.00E+03 6.21E-07 5. 35E-03 5. 38E-07 5.90E-Ol 

8.00E+03 6.00E-07 5. 96E-03 5.14E-07 5.90E-Ol 

9.00E+03 5.82E-07 6. 55E-03 4. 96E-07 5.91E-01 

1.00E+04 5.65E-07 7. 13E-03 4.81E-07 5.91E-Ol 

2.00E+04 4.24E-07 1.20E-02 . 3.61E-07 5. 95E-Ol 

B-458 
CLASS Y AMAD 1: 1 MICRON BALFLIFE= 2.39E+06 DAYS PLtrrONIUK 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------~----------~~---------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.00E-OI 3. 89E-03 3.04E-01 2. S8E-OI- 7.31E-02 6.39E-OI 

2.00E-OI 3.90E-03 2.8SE-OI 2.l7E-01 1. 33E-01 6.39E-OI 

3.00E-OI 3.90E-03 2.70E-0l 1.82E-01 1.82E-01 6.38E-OI 

4.00E-OI 3.90E-03 2.S7E-OI 1. S3E-OI 2.21E-OI 6. 36E-01 

S.OOE-OI 3. 89E-03 2.47E-OI 1.~9E-01 2. 52E-OI 6.32E-OI 

6.00E-OI 3. 89E-03 2. 38E-OI 1.!8E-01 2. 76E-01 6.27E-OI 

7.00E-01 3. 89E-03 2.31E-01 9. 2.E-02 2. 94E-Ol 6.20E-OI 

8.00E-Ol 3. 89E-03 2. 24E-OI 7" j7E-02 3.06E-OI 6.lOE-01 

9.00E-Ol 3. 89E-03 2.19E-Ol 6~ 45E-02 3.13E-01 6.00E-Ol 

l.OOE+OO 3.89E-03 2.i3E-01 5,42E-02 3.l6E-01 S.87E-01 

2.00E+OO 3.89E-03 l.80E-01 9 59E-03 2.32E-01 4. 26E-Ol 

3.00E+00 3.90E-03 l.6SE-01 1.70E-03 l.2SE-01 2.9SE-Ol 

4.00E+00 3.91E-03 1. S7E-Ol ' ,OOE-04 6.07E-02 2.22E-0l 

S.OOE+OO 3. 92E-03 l.S3E-Ol j.30E-OS 2. 86E-02 1. BSE-Ol 

6.00E+OO 3.93E-03 1. SlE-Ol 37E-06 l.3SE-02 l.6BE-0l 

7.00E+00 3.9SE-03 1. 49E-Ol ,6E-06 6. 44E-03 l.60E-01 

8.00E+00 3. 96E-03 l.49E-01 . !3E-07 3.1BE-03 l.S6E-01 

9.00E+00 3.9BE-03 l.4BE-01 iT ,; 7E-08 l.6SE-03 l.S4E-Ol 

l.OOE+01 3. 99E-03 l.4BE-Ol (, ,OOE+OO 9.2lE-04 l.S3E-01 

2.00E+Ol 4.ISE-03 1. 46E-OI 0, rnE+OO 2. 36E-'04 1.SlE-01 

3.00E+01 4.30E-03 1.4SE-OI o. tV) 2. 32E-04 l.49E-Ol 

4.00E+OI 4. 46E-03 1. 43E-OI 0.- ' 2. 29E-04 1.4BE-01 

S.OOE+Ol 4. 62E-03 1.42E-Ol C ~~. 26E-04 1.47E-Ol 

6.00E+Ol 4. 79E-03 1.41E-Ol 23E-04 1.46E-01 

7.00E+Ol 4.9SE-03 1.39E-01 GE-04 1. 44E-Ol 

8.00E+Ol S.12E-03 l.3BE-01 1~-04 l.43E-01 

9.00E+Ol S.2BE-03 l.36E-Ol 0 :.14 1. 42E-Ol 

l.00E+02 So.4SE-03 lo.3SE-01 o. 4 l.41E-01 

2.00E+02 7.13E-03 l.22E-0l 0.(; l.29E-Ol 

3.00E+02 B.B4E-03 1.10E-01 O.OOL 1. 19E-Ol 

4.00E+02 1.0SE-02 9.98E-02 O.OOE+, l.lOE-1)} 

S.OOE+02 1. 22E-02 9.06E-02 O.OOE+O(; 1.0':"-

6.00E+02 1. 39E-02 8. 23E-02 O.OOE+OO 9. 

7.00E+02 l.SSE-02 7.49E-02 O.OOE+OO ~~, 

8.00E+02 l.71E-02 6. 83E-02 O.OOE+OO 7. 99E-05 8~ 

9.00E+02 1. 86E-02 6.23E-02 O.OOE+OO 6. 96E-OS 8o.l - ,- l.00E+03 2.00E-02 50. 70E-02 Oo.OOE+OO 6o.06E-OS 7o.7li::·,v"::' 

2o.00E+03 3. 12E-02 2o.S4E-02 O.OOE+OO l.SIE-OS S.67E-02 

3.00E+03 3.71E-02 1. 34E-02 O.OOE+OO 3. 78E-06 So.04E-02 

4.00E+03 3. 96E-02 8.24E-03 O.OOE+OO 9.45E-07 4o.7BE-02 

So.OOE+03 4.03E-02 S.9lE-03 O.OOE+OO 2. 36E-07 4. 62E-02 

7.00E+03 3.9SE-02 4. 26E-03 O.OOE+OO 1. 48E-OB 4. 37E-02 

B.OOE+03 3o.B6E-02 3. 99E-03 O.OOE+OO O.OOE+OO 4. 26E-02 

9o.00E+03 3. 76E-02 3. 86E-03 O.OOE+OO O.OOE+OO 4.1SE-02 

1.00E+04 3.66E-02 3.79E-03 O.OOE+OO O.OOE+OO 4.04E-02 

2.00E+04 2.7SE-02 3. 72E-03 O.OOE+OO O.OOE+OO 3. 12E-02 

B-4S9 
CLASS Y AHA» = 1 MICRON BALFLIFE- 2.39£+06 DAYS PLUTONIUM 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---~--------------------------~-----------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1.68E-06 1. 19E-OS 

2.00E-Ol 3.SSE-06 2.13E-04 

3.00E-Ol S.32E-06 1.06E-03 

4.00E-Ol 7.01E-06 3.08E-03 

S.OOE-Ol 8. 61E-06 6. 67E-03 

6.00E-Ol I.OIE-OS I.2IE-02 

7.00E-Ol 1.16E-OS I.94E-02 

8.00E-OI 1.30E-OS 2. 86E-02 

9.00E-OI 1.43E-OS 3. 96E-02 

I.OOE+OO 1. SSE-OS I.SSE-OS S.21E-02 S.2IE-02 

2.00E+OO 9. 64E-06 2.S2E-OS I.6IE-0l 2.13E-OI 

3.00E+OO 6.09E-06 3.12E-OS I.31E-OI 3. 44E-OI 

4.00E+OO 4.0SE-06 3.S3E-OS 7.36E-02 4.17E-0l 

S.OOE+OO 2. 87E-06 3. 82E-OS 3. 64E-02 4.S4E-01 

6.00E+OO 2.18E-06 4.03E-OS I.73E-02 4.11E-OI 

7.00E+OO 1. 78E-06 4.21E-OS 8.l3E-03 4. 79E-OI 

8.00E+OO I.S3E-06 4. 37E-OS 3. 89E-03 4.83E-OI 

9.00E+OO I.38E-06 4.S0E-OS I.9IE-03 4.8SE-OI 

I.OOE+OI 1.29E-06 4. 63E-OS 9. 87E-04 4.86E-0l 

2.00E+OI 1.00E-06 S.73E-OS 1. 36E-04 4. 88E-Ol 

3.00E+OI 8.8IE-07 6. 66E-OS 1.34E-04 4.90E-OI 

4.00E+OI 8.04E-07 7.49E-OS 1. 32E-04 4.9IE-01 

S.OOE+Ol 7.S7E-07 8. 27E-OS 1.30E-04 4. 92E-OI 

6.00E+Ol 7. 28E-07 9.0IE-OS 1. 28E-04 4. 93E-OI 

7.00E+OI 7.12E-07 9.13E-OS 1. 26E-04 4.9SE-OI 

8.00E+Ol 7.03E-07 I.04E-04 I.2SE-04 4. 96E-OI 

9.00E+OI 6. 99E-07 I.llE-04 1. 23E-04 4. 97E-OI 

1.00E+02 6. 99E-07 I.I8E-04 I.2IE-04 4.98E-01 

2.00E+02 7. 37E-07 1.90E-04 I.06E-04 S.IOE-OI 

3.00E+02 7.80E-07 2. 66E-04 9.2IE-OS S.20E-OI 

4.00E+02 8.1SE-07 3.46E-04 8.03E-OS S.28E-Ol 

S.OOE+02 8.4SE-07 4. 29E-04 7.00E-OS S.36E-OI 

6.00E+02 8. 68E-07 S.I4E-04 6.11E-OS S.42E-OI 

7.00E+02 8. 86E-07 6.02E-04 S.33E-OS S.48E-OI 

8.00E+02 9.00E-07 6.9IE-04 4.6SE-OS S. S3E-OI 

9.00E+02 9.09E-07 7. 82E-04 4.06E-OS S. S7E-OI ; .. I.OOE+03 9. ISE-07 8. 73E-04 3.S4E-OS S.61E-Ol 

2.00E+03 8. 12E-07 1. 78E-03 9.40E-06 S.80E-OI 

3.00E+03 7. 88E-07 2.60E-03 2. 84E-06 S.86E-OI 

4.00E+03 7. 23E-07 3. 36E-03 1.I6E-06 S.87E-OI 

S.OOE+03 6. 78E-07 4.06E-03 7.13E-07 S.88E-0l 

7.00E+03 6.20E-07 S.3SE-03 S.37E-07 S.89E-OI 

8.00E+03 S.99E-07 S.9SE-03 S.13E-07 S.89E-Ol 

9.00E+03 S.8IE-07 6.S4E-03 4.9SE-07 S.89E-OI 

1.00E+04 S.63E-07 7.11E-03 4.80E-07 S.90E-OI 

2.00E+04 4. 22E-07 1.20E-02 3.60E-07 S.92E-OI 

B-460 
CLASS Y AHAD = 1 MICRON HALFLIFE= 1.37E+08 DAYS PLUTONIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------------~--

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3. 89E-03 3.04E-Ol 2.58E-Ol 7.3lE-02 6. 39E-Ol 

2.00E-Ol 3.90E-03 2.85E-Ol 2.l7E-Ol 1. 33E-Ol 6. 39E-Ol 

3.00E-Ol 3.90E-03 2.70E-Ol 1.82E-Ol 1.82E-OI 6.38E-Ol 

4.00E-OI 3.90E-03 2. 57E-Ol 1. 53E-Ol 2.2lE-Ol 6. 36E-Ol 

5.00E-Ol 3. 89E-03 2.47E-Ol 1.29E-Ol 2.52E-Ol 6. 32E-Ol 

6.00E-Ol 3. 89E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6.27E-Ol 

7.00E-0l 3. 89E-03 2.3lE-Ol 9.l2E-02 2. 94E-Ol 6.20E-Ol 

8.00E-Ol 3. 89E-03 2. 24E-Ol 7. 67E-02 3.06E-Ol 6.lOE-Ol 

9.00E-Ol 3. 89E-03 2.l9E-Ol 6.45E-02 3. 13E-Ol 6.00E-Ol 

1.OOE+OO 3. 89E-03 2. 13E-Ol 5. 42E-02 3.l6E-Ol 5. 87E-Ol 

2.00E+OO 3. 89E-03 1.80E-Ol 9. 59E-03 2. 32E-Ol 4.26E-Ol 

3.00E+OO 3.90E-03 1. 65E-Ol 1.70E-03 1. 25E-Ol 2. 95E-Ol 

4.00E+OO 3.9lE-03 1. 57E-Ol 3.00E-04 6.07E-02 2.22E-Ol 

5.00E+OO 3. 92E-03 1. 53E-Ol 5.30E-05 2. 86E-02 1. 85E-Ol 

6.00E+OO 3. 93E-03 1.5lE-0l 9.37E-06 1.35E-02 1. 68E-Ol 

7.00E+OO 3. 95E-03 1. 49E-Ol 1. 66E-06 6. 44E-03 1.60E-Ol 

8.00E+OO 3.96E-03 1.49E-OI 2. 93E-07 3.18E-03 1.56E-Ol 

9.00E+OO 3. 98E-03 1. 48E-Ol 5.l7E-08 1. 65E-03 1. 54E-Ol 

I.OOE+Ol 3.99E-03 1. 48E-Ol O.OOE+OO 9.2lE-04 1.53E-Ol 

2.00E+Ol 4.l5E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1.5lE-OI 

3.00E+Ol 4.30E-03 1.45E-0l O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+Ol 4. 46E-03 1.43E-Ol O.OOE+OO 2. 29E-04 1.48E-Ol 

5.00E+Ol 4.62E-03 1. 42E-0l O.OOE+OO 2.26E-04 1. 47E-Ol 

6.00E+Ol 4. 79E-03 1.4lE-Ol O.OOE+OO 2. 23E-04 1.46E-Ol 

7.00E+Ol 4. 95E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+Ol 5.l2E-03 1. 38E-Ol O.OOE+OO 2.l7E-04 1.43E-Ol 

9.00E+Ol 5. 28E-03 1.36E-Ol O.OOE+OO 2.l4E-04 1.42E-Ol 

1.OOE+02 5.45E-03 1. 35E-Ol O.OOE+OO 2.llE-04 1.4lE-Ol 

2.00E+02 7.13E-03 1. 22E-Ol O.OOE+OO 1.84E-04 1. 29E-Ol 

3.00E+02 8. 84E-03 1.lOE-Ol O.OOE+OO 1.60E-04 1.19E-Ol 

4.00E+02 1.05E-02 9.98E-02 O.OOE+OO 1.39E-04 1.lOE-0l 

5.00E+02 1. 22E-02 9.06E-02 O.OOE+OO 1.21E-04 1.03E-Ol 

6.00E+02 1. 39E-02 . 8.23E-02 O.OOE+OO 1.05E-04 9.63E-02 

7.00E+02 1. 55E-02 7. 49E-02 O.OOE+OO 9.18E-05 9.05E-02 

8.00E+02 1.71E-02 6. 83E-02 O.OOE+OO 7. 99E-05 8. 54E-02 

.... 9.00E+02 1. 86E-02 6. 23E-02 O.OOE+OO 6. 96E-05 8.l0E-02 , "'. . '. ~ . -.' ~ .:: ., .. ' 1.00E+03 2.00E-02 5.70E-02 O.OOE+OO 6.06E-05 7.71E-02 

2.00E+03 3. 12E-02 2. 55E-02 O.OOE+OO 1. 51E-05 5. 67E-02 

3.00E+03 3.71E-02 1.34E-02 O.OOE+OO 3. 79E-06 5.05E-02 

4.00E+03 3. 97E-02 8. 25E-03 O.OOE+OO 9. 46E-07 4. 79E-02 

5.00E+03 4.04E-02 5. 92E-03 O.OOE+OO 2.37E-07 4. 63E-02 

7.00E+03 3. 96E-02 4. 27E-03 O.OOE+OO 1. 48E-08 4. 38E-Q2 

8.00E+03 3. 87E-02 4.00E-03 O.OOE+OO O.OOE+OO 4.27E-02 

9.00E+03 3.77E-02 3. 87E-03 O.OOE+OO O.OOE+OO 4. 16E-02 

1.OOE+04 3. 67E-02 3.80E-03 O.OOE+OO O.OOE+OO 4.05E-02 

2.00E+04 2.77E-02 3. 74E-03 O.OOE+OO O.OOE+OO 3. 14E-02 

B-461 
CLASS Y AMAD = 1 KICRON BALFLIFE= 1.37E+OS DAYS PLUTONIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -~---~-------------~---~--------------~------~-~-~----

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.6BE-06 1.19E-OS 

2.00E-Ol 3.SSE-06 2.l3E-04 

3.00E-Ol S.32E-06 1.06E-03 

4.00E-Ol 7.01E-06 3.0BE-03 

5.00E-Ol B.61E-06 6.67E-03 

6.00E-Ol 1.OlE-05 1.21E-02 

7.00E-Ol 1.16E-05 1. 94E-02 

B.OOE-OI I.30E-05 2.B6E-02 

9.00E-Ol 1. 43E-:-05 3.96E-02 

1.OOE+OO I.55E-OS 1. 55E-05 5.21E-02 5.21E-02 

2.00E+OO 9.64E-06 2. 52E-OS I.61E-Ol 2.l3E-Ol 

3.00E+OO 6.09E-06 3.l2E-OS 1.31E-Ol 3.44E-Ol 

4.00E+OO 4.05E-06 3. 53E-05 7. 36E-02 4.17E-Ol 

5.00E+OO 2.B7E-06 3.B2E-05 3. 64E-02 4. 54E-Ol 

6.00E+OO 2.lBE-06 4.03E-05 1.73E-02 4.7IE-0l 

7.00E+OO 1.7BE-06 4.2lE-OS B.13E-03 ·4. 79E-Ol 

B.OOE+OO 1.53E-06 4.37E~05 3.B9E-03 4.B3E-Ol 

9.00E+OO I.3BE-06 4.S0E':"05 1.9lE-03 4.B5E-Ol 

I.OOE+Ol 1.29E-06 4. 63E-OS 9.B7E-04 4.86E-Ol 

2.00E+Ol 1.OOE-06 5. 73E:-:-Q,? 1. 36E-04 4.BBE-Ol 

3.00E+Ol 8.8lE-07 6. 66E-Q5_.< .. 1.34E-94 4.90E-Ol 

4.00E+Ol 8.04E-07 7 • 49E-05_ .. 1. 32E-04 4.91E-Ol 

5.00E+Ol 7.57E-07 B.27E-05 1.30E-04 4.92E-Ol 

6.00E+Ol 7.28E-07 9.01E-05 .. 1.2BE-04 4. 94E-Ol 

7.00E+Ol 7.12E-07 9. 73}!;-05_ - 1.26E-04 4. 95E-Ol 

B.OOE+Ol 7.03E-07 1.04E-04 1.2SE-04 4196E-Ol 

9.00E+Ol 6. 99E-07 1.llE-04 1.2:3E-04 4. 97E-Ol 

1.OOE+02 6. 99E-07 1.lBE-04 ... ~. ?lE-04 4.9BE-Ol 

2.00E+02 7.37E-07 1.90E-04_ - 1.Q6E-04 5.10E-Ol 

3.00E+02 7.80E-07 2 • .66E-04 _ e 9~~LE,..05 5.20E-Ol 

4.00E+02 B.15E-07 3. 46E-04 B • .Q3E_05 5. 28E-Ol 

5.00E+02 8.45E-07 4. 29E-04 . I.~ QOE.;-:.O 5 5.J6E-:Ol 

7.00E+02 8. 86E-07 6.02E-04 . .s. ._·~3E;::+05 5,..;;{f8~7.0 1 

8.00E+02 9.00E-07 6. 92E-04 4oR~5E;:05 . .?.·.~3E~Ol 

9.00E+02 9.09E-07 7. B2E-04 4.06E-05 .5;.,~~,!Ol 

1.OOE+03 9.15E-07 8. 73E-04 3. 54E-05 5.Q:U~~Ol 

2.00E+03 B.73E-07 1.7BE-03 9.4lE-06 5. 8U~,,!Ol .. 3.00E+03 7. 89E-07 2.6lE-03 2. 84E-06 5.B6E-Ol .. , , 

4.00E+03 7. 24E-07 3. 36E-03 1.16E-06 5.8BE-Ol 

5.00E+03 6.·79E-07 4.06E-03 7.l4E-07 5. 89E-Ol 

7.00E+03 6.22E-07 5. 36E-03 5.3BE-07 5.90E-Ol 

8.00E+03 6.01E-07 5. 97E-03 S.14E-07 5.90E-Ol 

9.00E+03 5.82E-07 6. 56E-03 4. 97E-07 5.9lE-Ol 

1.OOE+04 5. 65E-07 7.DE-03 4.BlE-07 5.91E-Ol 

2.00E+04 4. 25E-07 1.20E-02 3. 62E-07 5.96E-Ol 

B-462 
CLASS Y AHA» .. 1 HICR.ON HALFLllK= 1.S8E+05 DAYS AHEIlICIOM 241 

TIf:IE AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

I.OOE-OI 3.82E-03 3.04E-OI 2.S8E-O} 7.3IE-02 6. 39E-OI 

2.00E-O} 3.77E-03 2.8SE-OI 2.17E-OI 1. 33E-OI 6. 39E-OI 

3.00E-OI 3.73E-03 2.70E-OI 1. 82E-OI I.82E-OI 6.38E-OI 

4.00E-OI 3. 72E-03 2.S7E-OI I.S3E-OI 2.2IE-OI 6. 36E-Ol 

S.OOE-OI 3.70E-03 2.47E-OI 1.29E-0l 2.S2E-OI 6.,32E-OI 

6.00E-OI 3.70E-03 2. 38E-OI I.08E-OI 2. 76E-OI 6. 27E-OI 

7.00E-OI 3.70E-03 2.3IE-OI 9.12E-02 2.94E-OI 6.19E-OI 

8.00E-OI 3.70E-03 2. 24E-OI 7. 67E-02 3.0SE-OI 6.lOE-OI 

9.00E-Ol 3.70E-03 2.19E-OI 6.4SE-02 3.12E-OI S.99E-OI 

I.OOE+OO 3.70E-03 2.l3E-OI S.42E-02 3.lSE-OI S.87E-OI 

2.00E+OO 3. 74E-03 1.80E-OI 9.S9E-03 2. 32E-OI 4. 26E-OI 

3.00E+OO 3. 77E-03 1.6SE-OI I.70E-03 I.2SE-OI 2.9SE-OI 

4.00E+OO 3. 79E-03 I.S7E-0l 3.00E-04 6.07E-02 2.2lE-Ol 

S.OOE+OO 3.8IE-03 I.S3E-OI S.30E-OS 2. 86E-02 I.8SE-Ol 

6.00E+OO 3. 82E-03 1.SIE-OI 9. 36E-06 1. 34E-02 I.68E-Ol 

7.00E+OO 3. 84E-03 1. 49E-OI 1. 66E-06 6.44E-03 I.60E-OI 

8.00E+OO 3.8SE-03 1.49E-OI 2. 93E-07 3.18E-03 I.S6E-OI 

9.00E+OO 3. 87E-03 I.48E-OI S.I7E-08 1.6SE-03 I.S4E-OI 

I.OOE+OI 3. 89E-03 I.48E,..OI O.OOE+OO 9.20E-04 I.S3E-OI 

2.00E+OI 4.04E-03 l.46E-OI O.OOE+OO 2. 36E-04 I.SIE-OI 

3.00E+OI 4.20E-03 I.4SE-0l O.OOE+OO 2.32E-04 I.49E-Ol 

4.00E+OI 4.3SE-03 1. 43E-OI O.OOE+OO 2. 29E-04 1. 48E-Ol 

S.OOE+Ol 4.SIE-03 1.42E-Ol O.OOE+OO 2. 26E-04 I.47E-OI 

6.00E+Ol 4. 67E-03 I.40E-Ol O.OOE+OO 2. 23E-04 I.4SE-Ol 

7.00E+OI 4. 83E-03 1.39E-Ol O.OOE+OO 2.20E-04 1. 44E-Ol 

8.00E+Ol 4. 99E-03 1. 38E-OI O.OOE+OO 2.l7E-04 I.43E-OI 

9.00E+Ol S.lSE-03 1.36E-Ol O.OOE+OO 2.14E-04 I.42E-Ol 

I.OOE+02 S.3IE-03 I.3SE-OI O.OOE+OO 2.11E-04 I.40E-OI 

2.00E+02 6. 92E-03 1. 22E-OI O.OOE+OO I.83E-04 I.29E-OI 

3.00E+02 8.S6E-03 1.lOE-OI O.OOE+OO I.60E-04 1.19E-OI 

4.00E+02 1.02E-02 9. 96E-02 O.OOE+OO 1. 39E-04 I.lOE-Ol 

S.OOE+02 1.I8E-02 9.04E-02 O.OOE+OO 1.2IE-04 I.02E-OI 

7.00E+02 1.49E-02 7. 47E-02 O.OOE+OO 9. ISE-OS 8. 97E-02 

8.00E+02 1. 64E-02 6.80E-02 O.OOE+OO 7. 96E-OS 8. 46E-02 

9.00E+02 1. 79E-02 6.21E-02 O.OOE+OO 6. 93E-OS 8.00E-02 

", 1.OOE+03 1. 93E-02 S.68E-02 O.OOE+OO 6.03E-05 7.6IE-02 

2.00E+03 2.98E-02 2. 52E-02 O.OOE+OO I.SOE-05 5.5IE-02 

3.00E+03 3.S2E-02 l.32E-02 O.OOE+OO 3. 73E-06 4. 84E-02 

4.00E+03 3.74E-02 8. IOE-03 O.OOE+OO 9.30E-07 4.S5E-02 

S.OOE+03 , 3. 78E-02 S.79E-03 O.OOE+OO 2.3IE-07 4. 36E-02 

7.00E+03 3. 64E-02 4.14E-03 ' O.OOE+OO 1. 43E-08 4.0SE-02 

8.00E+03 3.S3E-02 3. 86E-03 O.OOE+OO O.OOE+OO 3. 92E-02 

9.00E+03 3. 42E-02 3.72E-03 O.OOE+OO O.OOE+OO 3.79E-02 

I.OOE+04 3.30E-02 3. 64E-03 O.OOE+OO O.OOE+OO 3. 67E-02 

2.00E+04 2.33E-02 3. 42E-03 O.OOE+OO O.OOE+OO 2. 68E-02 

B-463 
CLASS Y AKAD - 1 MICH.ON BALFLIFE= 1.58E+05 DAYS AMERICIUM 241 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 8.17E-05 1.04E-05 

2.00E-01 1. 56E-04 2.10E-04 

3.00E-01 2. 13E-04 1.06E-03 

4.00E-01 2. 57E-04 3.07E-03 

5.00E-01 2.91E-04 6. 67E-03 

6.00E-01 3. 17E:-04 1.21E-02 

7.00E-01 3. 38E-04 1.94E-02 

8.00E-01 3. 54E-04 2. 86E-02 

9.00E-01 3. 66E-04 3. 96E-02 

1.00E+OO 3. 76E-04 3. 76E-04 5.21E-02 5.21E-02 

2.00E+OO 3. 44E-05 4.10E-04 1.61E-01 2. 13E-01 

3.00E+OO 6.00E-06 4. 16E-04 1.31E-01 3. 44E-01 

4.00E+OO 2. 83E-06 4. 19E-04 7.36E-02 4. 17E-01 

5.00E+OO 2.21E-06 4.21E-04 3. 64E-02 4. 54E-01 

6.00E+OO 2.02E-06 4.23E-04 1.72E-02 4.71E-01 

7.00E+OO 1. 94E-06 4. 25E-04 8. 12E-03 4. 79E-01 

8.00E+OO 1.90E-06 4.27E-04 3.88E-03 4.83E-01 

9.00E+OO 1. 88E-06 4.29E-04 1. 91E-03 4.85E-01 

1.00E+01 1.87E-06 4.31E-04 9.85E-04 4.86E-01 

2.00E+01 1. 88E-06 4. 49E-04 1. 35E-04 4. 88E-01 

3.00E+01 1.89E-06 4.68E-04 1. 33E-04 4. 89E-01 

4.00E+01 1.90E-06 4. 87E-04 1. 31E-04 4.91E-01 

5.00E+01 1.91E-06 5.06E-04 1. 29E-04 4. 92E-01 

7.00E+01 1. 94E-06 5.45E-04 1. 26E-04 4.94E-01 

8.00E+01 1.95E-06 5.64E-04 1.24E-04 4.96E-01 

9.00E+01 1.96E-06 5. 84E-04 1. 22E-04 4. 97E-01 

1.00E+02 1.97E-06 6.03E-04 1.21E-04 4. 98E-01 

2.00E+02 2.06E-06 8.05E-04 1.05E-04 5.09E-01 

3.00E+02 2. 13E-06 1.01E-03 9. 13E-05 5. 19E-01 

4.00E+02 2. 18E-06 1. 23E-03 7. 95E-05 5.27E-01 

5.00E+02 2. 21E-06 1.45E-03 6. 91E-05 5.34E-01 

7.00E+02 2. 24E-06 1. 89E-03 5. 23E-05 5.46E-01 

8.00E+02 2. 24E-06 2. 12E-03 4.56E-05 5.50E-01 

9.00E+02 2. 24E-06 2. 34E-03 3. 96E-05 5. 54E-01 

" \ ',I 

.. 1.00E+03 2. 23E-06 2. 56E-03 3.45E-05 5. 58E-01 '.'- > 2.00E+03 1. 96E-06 4. 65E-03 8. 59E-06 5. 74E-01 

3.00E+03 1.69E-06 6. 44E-03 2. 14E-06 5. 76E-01 

4.00E+03 1.50E-06 7.99E-03 5. 32E-07 5. 75E-01 

5.00E+03 1.37E-06 9.38E-03 1.32E-07 5.72E-01 

7.00E+03 1.21E-06 1.18E-02 O.OOE+OO 5.67E-01 

8.00E+03 1. 15E-06 1.30E-02 O.OOE+OO 5. 65E-Ol 

9.00E+03 1.09E-06 1.40E-02 O.OOE+OO 5. 62E-Ol 

1.00E+04 1.05E-06 1.50E-02 O.OOE+OO 5.60E-Ol 

2.00E+04 6.90E-07 2. 27E-02 O.OOE+OO 5. 36E-Ol 

B-464 
CLASS Y AHAD = 1 KICRON HALFLIFE= 2.69E+06 DAYS AMERICIUM 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC NASAL GI TOTAL 

DAYS ORGANS LUNGS PASSAGES TRACT BODY 

1.OOE-Ol 3.82E-03 3.04E-Ol 2. S8E-Ol 7.3lE-02 6.39E-Ol 

2.00E-Ol 3.77E-03 2.8SE-Ol 2.l7E-Ol 1. 33E-Ol 6.39E-Ol 

3.00E-Ol 3.73E-03 2.70E-Ol 1.82E-Ol 1.82E-Ol 6.38E-Ol 

4.00E-Ol 3.72E-03 2.S7E-Ol 1.S3E-Ol 2.2lE-Ol 6. 36E-Ol 

S.OOE-Ol 3.70E-03 2.47E-Ol 1.29E-Ol 2. S2E-Ol 6. 32E-Ol 

6.00E-Ol 3.70E-03 2. 38E-Ol 1.08E-Ol 2. 76E-Ol 6.27E-Ol 

7.00E.-Ol 3.70E-03 2.3lE-Ol 9.l2E-02 2.94E-Ol 6.l9E-Ol 

8.00E"\Ol 3.70E-03 2. 24E-Ol 7.67E-02 3.0SE-Ol 6.lOE-Ol 

9.00E-Ql 3.70E-03 2.l9E-Ol 6.4SE-02 3.l2E-Ol S.99E-Ol 

1.OOE+OO 3.70E-03 2.l3E-Ol S.42E-02 3.lSE-Ol S.87E-Ol 

2.00E+OO 3. 74E-03 1.80E-Ol 9.S9E-03 2.32E-Ol 4.26E-Ol 

3.00E+OO 3.77E-03 1.6SE-Ol 1.70E-03 1.2SE-Ol 2.9SE-Ol 

4.00E+OO 3.79E-03 1.S7E-Ol 3.00E-04 6.07E-02 2.2lE-Ol 

S.OOE+OO 3.8lE-03 1.S3E-Ol S.30E-OS 2. 86E-02 1.8SE-Ol 

6.00E+OO 3.82E-03 1. SIE-Ol 9.37E-06 1.34E-02 1.68E-Ol 

7.00E+OO 3. 84E-03 1.49E-Ol 1.66E-06 6.44E-03 1.60E-Ol 

8.00E+OO 3.8SE-03 1.49E-Ol 2. 93E-07 3.l8E-03 1. S6E-Ol 

9.00E+OO 3.87E-03 1.48E-Ol S.17E-08 1.6SE-03 1.S4E-Ol 

1.OOE+Ol 3. 89E-03 1.48E-Ol O.OOE+OO 9.20E-04 1. S3E-Ol 

2.00E+Ol 4.04E-03 1.46E-Ol O.OOE+OO 2. 36E-04 1.SlE-Ol 

3.00E+Ol 4.20E-03 1.4SE-Ol O.OOE+OO 2.32E-04 1.49E-Ol 

4.00E+Ol 4.36E-03 1.43E-Ol O.OOE+OO 2.29E-04 1.48E-Ol 

S.OOE+Ol 4.SlE-03 1.42E-Ol O.OOE+OO 2.26E-04 1.47E-Ol 

6.00E+Ol 4.67E-03 1.4lE-Ol O.OOE+OO 2. 23E-04 1.4SE-Ol 

7.00E+Ol 4. 83E-03 1.39E-Ol O.OOE+OO 2.20E-04 1.44E-Ol 

8.00E+Ol 4. 99E-03 1. 38E-Ol O.OOE+OO 2.l7E-04 1.43E-Ol 

9.00E+Ol S.lSE-03 1.36E-Ol O.OOE+OO 2.l4E-04 1.42E-Ol 

1.OOE+02 S.3lE-03 1.3SE-Ol O.OOE+OO 2.11E-04 1.40E-Ol 

2.00E+02 6.93E-03 1.22E-Ol O.OOE+OO 1.84E-04 1.29E-Ol 

3.00E+02 8.S7E-03 1. lOE-Ol O.OOE+OO 1.60E-04 1.19E-Ol 

4.00E+02 1.02E-02 9.98E-02 O.OOE+OO 1.39E-04 1. lOE-Ol 

S.OOE+02 1.18E-02 9.06E-02 O.OOE+OO 1.2lE-04 1.03E-Ol 

7.00E+02 1.SOE-02 7.49E-02 O.OOE+OO 9.l8E-OS 9.00E-02 

8.00E+02 1.6SE-02 6. 83E-02 O.OOE+OO 7.99E-OS 8.48E-02 

9.00E+02 1.79E-02 6. 23E-02 O.OOE+OO 6.9SE-OS 8.03E-02 

1.OOE+03 1.94E-02 S.70E-02 O.OOE+OO 6.0SE-OS 7. 64E-02 

\ ",1 

; . 

,. 2.00E+03 3.0lE-02 2.S4E-02 O.OOE+OO 1.SlE-OS S. SSE-02 

3.00E+03 3.S7E-02 1.34E-02 O.OOE+OO 3. 78E-06 4.90E-02 

4.00E+03 3.80E-02 8. 24E-03' O.OOE+OO 9.4SE-07 4. 62E-02 

S.OOE+03 3. 86E-02 S.9lE-03 O.OOE+OO 2. 36E-07 4.4SE-02 

7.00E+03 3.7SE-02 4.26E-03 O.OOE+OO 1.48E-08 4.l7E-02 

8.00E+03 3.6SE-02 3. 99E-03 O.OOE+OO O.OOE+OO 4.0SE-02 

9.00E+03 3.SSE-02 3.86E-03 O.OOE+OO O.OOE+OO 3.93E-02 

1.OOE+04 3. 44E-02 3. 79E-03 O.OOE+OO O.OOE+OO 3. 82E-02 

2.00E+04 2.S3E-02 3.72E-03 O.OOE+OO O.OOE+OO 2.9lE-02 

B-46S 
CLASS Y AMAD - 1 MICRON HALFLII'K= 2.69E+06 DAYS AHERICIDH 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 8. 17E-05 1.04E-05 

2.00E-01 1.56E-04 2.10E-04 

3.00E-Ol 2. 13E-04 1.06E-03 

4.00E-01 2.57E-04 3.0n~-03 

5.00E-01 2.91E-04 6.67E-03 

6.00E-01 3. 17E-04 1.21E-02 

7.00E-01 3.38E-04 1.94E-02 

8.00E-01 3. 54E-04 2. 86E-02 

9.00E-Ol 3.66E-04 3.96E-02 

1.00E+00 3. 76E-04 3. 76E-04 5.21E-02 5.21E-02 

2.00E+00 3. 44E-05 4.10E-04 1.61£-01 2. 13E-01 

3.00E+00 6.00E-06 4. 16E-04 1.31E-01 3.44E-01 

4.00E+00 2. 83E-06 4. 19E-04 7.36E-02 4.17E-01 

5.00E+00 2.21E-06 4.21E-04 3.64E-02 4.54E-Ol 

6.00E+00 2.02E-06 4.23E-04 1.72E-02 4. 71E-01 

7.00E+00 1.94E-06 4.25E-04 8. 12E-03 4.79E-01 

8.00E+00 1.90E-06 4. 27E-04 3. 88E-03 4.83E-01 

9.00E+OO 1.88E-06 4.29E-04 1.91E-03 4.85E-01 

1.00E+01 1.87E-06 4.31£-04 9. 85E-04 4. 86E-Ol 

2.00E+01 1. 88E-06 4.49E-04 1.36E-04 4. 88E-Ol 

3.00E+01 1. 89E-06 4.68E-04 1. 33E-04 4.89E-Ol 

4.00E+01 1.90E-06 4. 87E-04 1.31E-04 4.91E-Ol 

5.00E+01 1.91E-06 5.06E-04 1.29E-04 4.92E-01 

7.00E+Ol 1.94E-06 5.45E-04 1.26E-04 4. 94E-Ol 

8.00E+01 1.95E-06 5'. 64E-04 1.24E-04 4.96E-Ol 

9.00E+01 1. 96E-06 5.84E-04 1.22E-04 4.97E-01 

1.00E+02 1.97E-06 6.04E-04 1. 21E-04 4.98E-Ol 

2.00E+02 2.06E-06 8.05E-04 1.05E-04 5.09E-01 

3.00E+02 2.13£-06 1.02E-03 9. 14E-05 5. 19E-Ol 

4.00E+02 2. 18E-06 1.23E-03 7. 96E-05 5.28E-Ol 

5.00E+02 2.22E-06 1.45E-03 6.93E-05 5.35E-01 

7.00E+02 2.25E-06 1.90E-03 5.25E-05 5.47E-01 

8.00E+02 2.25E-06 2. 12E-03 4.57E-05 5.52E-01 

9.00E+02 2. 25E-06 2. 35E-03 3. 98E-05 5. 56E-Ol 

1.00E+03 2.23E-06 2.57E-03 3.46E-05 5.60E-01 

2.00E+03 1.97E-06 4.69E-03 8. 66E-06 5.79E-Ol 

3.00E+03 1.71E-06 6.52E-03 2. 16E-06 5.83E-01 

4.00E+03 1.52E-06 8.12E-03 5.'+lE-07 5.84E-01 

5.001+03 1.40E-06 9.58E-03 1.35E-07 5.84E-Ol 

7.00E+03 1.24E-06 1.22E-02 O.OOE+OO 5. 84E-01 

8.00E+03 1. 18E-06 1.34E-02 O.OOE+OO 5.84E-01 

9.00E+03 1. 14E-06 1.46E-02 O.OOE+OO 5. 84E-Ol 

1.00E+04 1.09E-06 1.57E-02 O.OOE+OO 5. 84E-Ol 

2.00E+04 7.50E-07 2.47E-02 0.00£+00 5.82E-01 

B-466 
£9.,-a 

NOIJ.S3!)RI 3"IDNIS 110 .. SNOIJ.:)YU NOIJ.mI!JX3 OHV HOIlRU38 lIOil SWUIYJ. .~ 
"'. : .: ' 

INGESTION £1= 5.00£-03 BALFLIFE= 5.33£+01 DAYS BERYLLIUM 7 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

DAYS 

I.OOE-OI 

2.00E-OI 

3.00E-OI 

4.00E-OI 

S.OOE-OI 

6.00E-OI 

7.00E-OI 

8.00E-0l 

9.00E-OI 

I.OOE+OO 

2.00E+OO 

3.00E+OO 

4.00E+OO 

S.OOE+OO 

6.00E+OO 

7.00E+OO 

8.00E+OO 

9.00E+OO 

I.OOE+OI 

2.00E+OI 

3.00E+OI 

4.00E+OI 

5.00E+OI 

6.00E+Ol 

7.00E+Ol 

8.00E+OI 

9.00E+Ol 

1.OOE+02 

2.00E+02 

3.00E+02 

4.00E+02 

5.00E+02 

6.00E+02 

7.00E+02 

8.00E+02 

9.00E+02 

SYSTEMIC 

ORGANS 

1. 43E-03 

2.73E-03 

3. 34E-03 

3. 55E-03 

3.S7E-03 

3.SlE-03 

3. 42E-03 

3. 33E-03 

3. 24E-03 

3.17E-03 

2. 88E-03 

2. 79E-03 

2.72E-03 

2. 66E-03 

2.60E-03 

2. S4E-03 

2.4SE-03 

2.42E-03 

2. 37E-03 

1.93E-03 

1.6IE-03 

1. 36E-03 

1.l6E-03 

1.00E-03 

S.70E-04 

7.S6E-04 

6.S9E-04 

5. 74E-04 

1.49E-04 

3.S7E-OS 

1. OlE-OS 

2. 62E-06 

6.SlE-07 

1.77E-07 

4.6IE-OS 

I.20E-OS 

B-468 

GI 

TRACT 

9. 97E-01 

9.S9E-Ol 

9. 73E-01 

9.49E-OI 

9.1SE-Ol 

S.SOE-Ol 

S.38E-Ol 

7.94E-OI 

7.47E-Ol 

7.00E-01 

3.14E-Ol 

1.23E-Ol 

4.61E-02 

l.70E-02 

6.20E-03 

2. 26E-03 

8.20E-04 

2.9SE-04 

1.08E-04 

O.OOE+OO 

.O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

TOTAL 

BODY 

9.9SE-Ol 

9.91E-Ol 

9. 76E-Ol 

9.S3E-Ol 

9.2lE-0l 

8.84E-01 

S.42E-Ol 

7.97E-Ol 

7. SlE-Ol 

7.04E-Ol 

3.16E-Ol 

l.26E-OI 

4.S9E-02 

l.96E-02 

8.80E-03 

4. 79E-03 

3.30E-03 

2. 72E-03 

2.4SE-03 

l.93E-03 

1.61E-03 

1.36 

l.l6E-03 

I.OOE-03 

8.70E-04 

7.S6E-04 

6.S9E-04 

S.74E-04 

1. 49E-04 

3.87E-05 

I.OIE-OS 

2. 62E-06 

6.8IE-07 

1. 77E-07 

4.6lE-08 

I.20E-08 
DlGESTIOB f 1- 5.00£-03 BALPLlFE= 5.33£+01 DAYS BERYLLIUM 7 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------~----~------------- SYSTEMIC NON-SYSTEMIC 

-~----------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 6. 41E-05 6.08E-04 

2.00E-01 2.77E-04 5. 88E-03 

3.00E-01 5. 53E-04 1. 92E-02 

4.00E-01 8. 26E-04 4. 13E-02 

5.00E-01 1.07E-03 7.11E-02 

6.00E-01 1. 27E-03 1.07E-01 

7.00E-01 1. 44E-03 1. 48E-Ol 

8.ooE-01 1. 57E-03 1.91E-01 

9.00E-01 1. 67E-03 2. 36E-01 

1.00E+00 1. 75E-03 1. 75E-03 2. 82E-01 2. 82E-01 

2.00E+00 2. 69E-04 2.00E-03 3.78E-01 6. 56E-01 

3.00E+00 4.77E-05 2.02E-03 1. 86E-01 8. 34E-01 

4.00E+00 3.20E-05 2.02E-03 7. 54E-02 8. 98E-01 

5.00E+QO 2. 94E-05 2.03E-03 2. 86E-02 9. 15E-01 

6.00E+00 2. 77E-05 2.03E-03 1.06E-02 9. 14E-01 

7.00E+00 2. 62E-05 2.03E-03 3. 86E-03 9.06E-01 

8.00E+00 2.47E-05 2.03E-03 1.41E-03 8. 96E-01 

9.00E+00 2. 33E-05 2.02E-03 5. 12E-04 8. 85E-01 

1.00E+01 2.20E-05 2.02E-03 1. 86E-04 8. 74E-01 

2.0(}E+01 1. 25E-05 1. 93E-03 O.OOE+OO 7.67E-01 

3.00E+01 7. 14E-06 1. 78E-03 O.OOE+OO 6. 74E-01 

4.00E+01 4. 17E-06 1. 61E-03 O.OOE+OO 5. 91E-01 

5.00E+01 2.50E-06 1.45E-03 O.OOE+OO 5. 19E-01 

6.00E+01 1. 55E-06 1. 29E-03 O.OOE+OO 4. 56E-01 

7.00E+01 1.00E-06 1. 14E-03 O.OOE+oo 4.00E-01 

8.00E+01 6. 81E-07 1.OlE-03 O.OOE+OO 3. 52E-01 

9.00E+01 4. 88E-07 8.92E-04 O.OOE+OO 3.09E-01 

1.00E+02 3. 67E-07 7. 88E-04 O.OOE+OO 2. 71E-01 

2.00E+02 6.91E-08 2. 22E-04 O.OOE+OO 7.38E-02 

3.00E+02 1. 79E-08 6. 24E-05 O.OOE+OO 2.01E-02 

8-469 
INGESTION f l - 5.00E-ol STABLE BERYLLIUM 9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEHIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 1. 43E-03 9. 98E-OI 9. 99E-OI 

2.00E-OI 2. 74E-03 , 9.9IE-D1 9.94E-OI 

3.00E-OI 3.3SE-03 9.77E-OI 9.80E-OI 

4.00E-OI 3.S7E-03 9.S4E-OI 9.SBE-OI 

S.OOE-OI 3.60E-03 9.24E-OI 9.27E-OI 

6.00E-OI 3.S4E-03 B.B7E-OI B.9IE-OI 

7.00E-OI 3.4SE-03 B.46E-OI B.SOE-OI 

B.OOE-OI 3.36E-03 B.02E-OI B.OSE-OI 

9.00E-OI 3.2BE-03 7.S6E-OI 7.S9E-OI 

I.OOE+OO 3.2IE-03 7.10E-OI 7.13E-OI 

2.00E+OO 2.9SE-03 3. 22E-OI 3.2SE-OI 

3.00E+OO 2.90E-03 1.2BE-OI 1.3IE-OI 

4.00E+OO 2. 87E-03 4.B6E-02 S.ISE-02 

S.OOE+OO 2.B4E-03 I.BIE-02 2.lOE-02 

6.00E+OO 2.BIE-03 6.70E-03 9.SIE-03 

7.00E+OO 2.7BE-03 ' 2.47E-03 S.2SE-03 

B.OOE+OO 2.7SE-03 9.10E-04 3. 66E-03 

9.00E+OO 2.72E-03 3. 35E-04 3.06E-03 

I.OOE+OI 2.70E-03 1.23E-04 2.B2E-03 

2.00E+OI 2.S0E-03 O.OOE+OO 2.S0E-03 

3.00E+OI 2. 37E-03 O.OOE+OO 2.37E 

4.00E+OI 2. 29E-03 O.OOE+OO 2.29E-O 

S.OOE+OI 2.23E-03 O.OOE+OO 2. 

6.00E+OI 2.19E-03 O.OOE+OO 2.19E-03 

7.00E+Ol 2.16E-03 O.OOE+OO 2.16E-03 

8.00E+OI 2.14E-03 O.OOE+OO 2.14E-03 

9.00E+OI 2.12E-03 O.OOE+OO '2.12E-03 

I.OOE+02 2.llE-03 O.OOE+OO 2.11E-03 

2.00E+02 2.0IE-03 O.OOE+OO 2.0IE-03 

3.00E+02 1. 92E-03 O.OOE+OO 1. 92E-03 

4.00E+02 I.B3E-03 O.OOE+OO I.B3E-03 

S.OOE+02 1.7SE-03 O.OOE+OO 1.7SE-03 

6.00E+02 1.67E-03 O.OOE+OO 1.67E-03 

7.00E+02 I.S9E-03 O.OOE+OO I.S9E-03 

B.OOE+02 I.S2E-03 O.OOE+OO 1. 52E-03 

9.00E+02 1.4SE-03 O.OOE+OO 1.4SE-03 

I.OOE+03 1. 39E-03 O.OOE+OO 1. 39E-03 

2.00E+03 B.73E-04 O.OOE+OO B.73E-04 

3.00E+03 S.50E-04 O.OOE+OO S.SOE-04 

4.00E+03 3. 47E-04 O.OOE+OO 3. 47E-04 

5.00E+03 2.IBE-04 O.OOE+OO 2.IBE-04 

7.00E+03 8. 67E-OS O.OOE+OO 8.67E-OS 

B.OOE+03 5. 46E:-05 O.OOE+OO S.46E-OS 

9.00E+03 3. 44E-OS O.OOE+OO 3. 44E-OS 

I.OOE+04 2.17E-OS O.OOE+OO 2.17E-OS 

2.00E+04 2.14E-07 O.OOE+OO 2.14E-07 

B-470 
INGESTION £1= 5.ooE-03 STABLE BERYLLIUM 9 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------~------------------------------~---------

SYSTEMIC NON-SYSTEMIC 

-----~------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6.42E-OS 6.09E-04 

2.00E-Ol 2.7SE-04 S.90E-03 

3.00E-Ol S.SSE-04 1.93E-02 

4.00E-Ol S.30E-04 4.lSE-02 

S.OOE-Ol 1.OSE-03 7·l6E-02 

6.00E-Ol 1.2SE-03 1.08E-Ol 

7.00E-Ol 1.4SE-03 1. 49E-Ol 

8.00E-Ol 1.S8E-03 1. 93E-Ol 

9.00E-0l 1. 69E-03 2.39E-Ol 

1.OOE+OO 1.77E-03 1.77E-03 2.8SE-Ol 2.SSE-Ol 

2.00E+OO 2. 76E-04 2.0SE-03 3. 88E-Ol 6.73E-Ol 

3.00E+OO 4. 96E-OS 2.10E-03 1. 94E-Ol S.67E-Ol 

4.00E+OO 3. 37E-OS 2.13E-03 7.94E-02 9. 46E-Ol 

S.OOE+OO 3.14E-OS 2.l6E-03 3.0SE-02 9.77E-Ol 

6.00E+OO 3.00E-OS 2.19E-03 1.14E-02 9.SBE-Ol I 7.00E+OO 2.B7E-OS 2. 22E-03 4. 23E-03 9. 93E-Ol 

B.OOE+OO 2. 74E-OS 2.2SE-03 1.S6E-03 9. 94E-Ol 

9.00E+OO 2. 62E-OS 2. 28E-03 S.7SE-04 9.9SE-Ol 

I.OOE+OI 2.SIE-OS 2.30E-03 2.l2E-04 9.9SE-OI 

2.00E+Ol I. 62E-OS 2.S0E-03 O.OOE+OO 9.9SE-OI 

3.00E+Ol 1.06E-OS 2. 63E-03 O.OOE+OO 9.9SE-Ol 

4.00E+Ol 7.02E-06 2.71E-03 O.OOE+OO 9.9SE-Ol 

S.OOE+Ol 4.7SE-06 2. 77E-03 O.OOE+OO 9.9SE-Ol 

6.00E+Ol 3. 38E-06 2.81E-03 O.OOE+OO 9.9SE-Ol 

7.00E+Ol 2. 49E-06 2.S4E-03 O.OOE+OO 9.9SE-Ol. 

8.00E+Ol l.93E-06 2.B6E-03 O.OOE+OO 9.9SE-Ol 

9.00E+Ol 1.S7E-06 2.8SE-03 O.OOE+OO 9.9SE-Ol 

1.OOE+02 l.3SE-06 2. 89E-03 O.OOE+OO 9.9SE-OI 

2.00E+02 9.3lE-07 2. 99E-03 O.OOE+OO 9.9SE-Ol 

3.00E+02 8.8SE-07 3.0SE-03 O.OOE+OO 9.9SE-Ol 

4.00E+02 8.ASE-07 3.17E-03 O.OOE+OO 9.9SE-Ol 

5.00E+02 8.07E-07 3.2SE-03 O.OOE+OO 9.9SE-Ol 

7.00E+02 7.36E-07 3.41E-03 O.OOE+OO 9.9SE-Ol 

S.OOE+02 7.03E-07 3.4SE-03 O.OOE+OO 9.9SE-OI 

9.00E+02 6.7lE-07 3.SSE-03 O.OOE+OO 9.9SE-Ol 

l.OOE+03 6.4lE-07 3.6lE-03 O.OOE+OO 9.95E-Ol 

2.00E+03 4.04E-07 4.13E-03 O.OOE+OO 9.9SE-Ol 

3.00E+03 2. 54E-07 4.4SE-03 O.OOE+OO 9.9SE-Ol 

4.00E+03 1.60E-07 4. 65E-03 O.OOE+OO 9.9SE-Ol 

S.OOE+03 I.OIE-07 4.7SE-03 O.OOE+OO 9.9SE-OI 

7.00E+03 4.0IE-08 4.9IE-03 O.OOE+OO 9.9SE-OI 

B.OOE+03 2.S2E-08 4. 95E-03 O.OOE+OO 9. 95E-O I 

9.00E+03 I.S9E-08 4.97E-03 O.OOE+OO 9.9SE-OI 

l.OOE+04 1.OOE-08 4. 98E-03 O.OOE+90 9.9SE-OI 

B-471 
INGESTION fl= 1.OOE+OO STABLE FLOURINE 19 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------~----------~--- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 9.09E-Ol 9.07E-02 1.OOE+OO 

2.00E-Ol 9. 92E-Ol 8.23E-03 1.00E+OO 

3.00E-Ol 9. 99E-Ol 7. 48E-04 1.00E+OO 

4.00E-Ol 1.00E+OO 6.86E-05 1.00E+OO 

5.00E-Ol 1.00E+OO 7.02E-06 1.00E+OO 

6.00E-Ol 1.OOE+OO 1.38E-06 1.00E+OO 

7.00E-Ol 1.00E+OO 8.30E-07 1.00E+OO 

8.00E-Ol 1.00E+OO 7. 35E-07 1.00E+OO 

9.00E-Ol 1.OOE+OO 6. 83E-07 1.00E+OO 

1.00E+OO 1.00E+OO 6. 35E-07 1.00E+OO 

2.00E+OO 1.00E+OO 2.76E-07 1.00E+OO 

3.00E+OO 1.00E+OO 1.08E-07 1.00E+OO 

4.00E+OO 1.00E+OO 4.09E-08 1.00E+OO 

5.00E+OO 1.00E+OO 1. 52E-08 1.00E+OO 

6.00E+OO 1.00E+OO O.OOE+OO 1.00E+OO 

7.00E+OO 1.00E+OO O.OOE+OO 1.00E+OO 

8.00E+OO 1.00E+OO O.OOE+OO 1.00E+OO 

9.00E+OO 1.00E+OO O.OOE+OO 1.00E+OO 

1.00E+Ol 1.00E+OO O.OOE+OO 1.OOE+OO 

2.00E+Ol 1.00E+OO ·O.OOE+OO 1.00E+OO 

3.00E+Ol 1.00E+OO O.OOE+OO 1.00E+OO 

4.00E+Ol 1.00E+OO O.OOE+OO 1. 

5.00E+Ol 1.00E+OO O.OOE+OO 1.00E+ 

6.00E+Ol 1.00E+OO O.OOE+OO 1.00E+OO 

7.00E+Ol 1.00E+OO O.OOE+OO 1.00E+OO 

8.00E+Ol 1.00E+OO O.OOE+OO 1.00E+OO 

9.00E+Ol 1.00E+OO O.OOE+OO 1.00E+OO 

1.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

2.00E+02 1.OOE+OO O.OOE+OO 1.00E+OO 

3.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

4.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

5.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

6.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

7.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

8.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

9.00E+02 1.00E+OO O.OOE+OO 1.00E+OO 

1.00E+03 1.00E+OO O.OOE+OO 1.00E+OO 

2.00E+03 1.OOE+OO O.OOE+OO 1.00E+OO 

3.00E+03 1.OOE+OO O.OOE+OO 1.00E+OO 

4.00E+03 1.00E+OO O.OOE+OO 1.00E+OO 

5.00E+03 1.00E+OO O.OOE+OO 1.OOE+OO 

7.00E+03 1.OOE+OO O.OOE+OO 1.00E+OO 

8.00E+03 1.00E+OO O.OOE+OO 1.00E+OO 

9.00E+03 1.00E+OO O.OOE+OO 1.OOE+OO 

1.00E+04 1.00E+OO O.OOE+OO 1.OOE+OO 

2.00E+04 1.00E+OO O.OOE+OO 1.00E+OO 

-

:S-472 
INGESTION £1= 1.00E+OO STABLE SODIUM 23 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 9.0SE-Ol 9.07E-02 9. 96E-Ol 

2.00E-Ol 9.81E-Ol 8.23E-03 9. 89E-Ol 

3.00E-Ol 9. 82E-OI 7.48E-04 9. 82E-Ol 

4.00E-OI 9.7SE-Ol 6.86E-OS 9. 76E-Ol 

S.OOE-Ol 9. 69E-Ol 7.02E-06 9. 69E-Ol 

6.00E-Ol 9. 62E-OI 1. 38E-06 9. 62E-OI 

7.00E-Ol 9.S6E-OI 8.30E-07 9.S6E-OI 

8.00E-Ol 9.49E-OI 7.3SE-07 9.49E-Ol 

9.00E-OI 9. 42E-OI 6.83E-07 9.42E-Ol 

1.OOE+OO 9. 36E-OI 6.3SE-07 9. 36E-Ol 

2.00E+OO 8. 73E-OI 2. 76E-07 8. 73E-Ol 

3.00E+OO 8.ISE-OI I.08E-07 8.1SE-OI 

4.00E+OO 7.6IE-OI 4.09E-08 7.6IE-Ol 

5.00E+OO 7.10E-Ol I.S2E-08 7.10E-OI 

6.00E+OO 6. 63E-OI O.OOE+OO 6. 63E-OI 

7.00E+OO 6.19E-Ol O.OOE+OO 6.19E-Ol 

8.00E+OO 5.77E-OI O.OOE+OO S.77E",:"OI 

9.00E+OO S.39E-OI O.OOE+OO 5.39E-Ol 

1.OOE+OI 5.03E-OI O.OOE+OO 5.03E-OI 

2.00E+Ol 2.S3E-OI O.OOE+OO 2. 53E-Ol 

3.00E+OI I.28E-Ol O.OOE+OO 1.28E-Ol 

4.00E+OI 6.S4E-02 O.OOE+OO 6. 54E-02 

5.00E+OI 3.4IE-02 O.OOE+OO 3.41E-02 

6.00E+Ol 1. 84E-02 O.OOE+OO 1. 84E-02 

7.00E+OI I.05E-02 O.OOE+OO 1.OSE-02 

8.00E+OI 6.60E-03 O.OOE+OO 6.60E-03 

9.00E+OI 4.60E-03 O.OOE+OO 4.60E-03 

I.OOE+02 3.S9E-03 O.OOE+OO 3.S9E-03 

2.00E+02 2. 27E-03 O.OOE+OO 2. 27E-03 

3.00E+02 1. 98E-03 O.OOE+OO 1. 98E-03 

4.00E+02 1. nE-03 O.OOE+OO 1. 72E-03 

5.00E+02 I.SOE-03 O.OOE+OO I.SOE-03 

6.00E+02 I.3IE-03 O.OOE+OO I.3IE-03 

7.00E+02 I.14E-03 O.OOE+OO 1.I4E-03 

8.00E+02 9.90E-04 O.OOE+OO 9.90E-04 

9.00E+02 8. 62E-04 O.OOE+OO 8. 62E-04 

1.OOE+03 7.50E-04 O.OOE+OO 7.50E-04 

2.00E+03 I. 88E-04 O.OOE+OO 1. 88E-04 

3.00E+03 4. 69E-05 O.OOE+OO 4.69E-05 

4.00E+03 I.17E-05 O.OOE+OO I.l7E-05 

5.00E+03 2. 93E-06 O.OOE+OO 2.93E-06 

6.00E+03 7. 34E-07 O.OOE+OO 7.34E-07 

7.00E+03 I.83E-07 O.OOE+OO 1. 83E-07 

8.00E+03 4. 59E-08 O.OOE+OO 4. 59E-08 

9.00E+03 I.15E-08 O.OOE+OO 1.ISE-08 

B-473 
INGESTION fl= 1.00E+OO STABLE SODIUM 23 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------------~--------------

SYSTEMIC NON-SYSTEMIC 

---~--------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 4.2SE-03 4.2SE-OS 

2.00E-Ol 1. 09E-02 1.09E-04 

3.00E-Ol 1.77E-02 1.77E-04 

4.00E-Ol 2.4SE-02 2.4SE-04 

S.OOE-Ol 3.l2E-02 3.l2E-04 

6.00E-OI 3.7SE-02 3. 79E-04 

7.00E-OI 4.4SE-02 4.4SE-04 

S.OOE-Ol S.lOE-02 S.11E-04 

9.00E-Ol S.76E-02 S.76E-04 

1.OOE+OO 6.4lE-02 6.4lE-02 6.4lE-04 6.4IE-04 

2.00E+OO 6.2SE-02 1.27E-Ol 6.2SE-04 1.27E-03 

3.00E+OO S.S3E-02 I.SSE-OI S.S3E-04 1.SSE-03 

4.00E+OO S.44E-02 2. 39E-Ol S.44E-04 2. 39E-03 

S.OOE+OO S.07E-02 2.90E-Ol S.07E-04 2.90E-03 

6.00E+OO 4. 73E-02 3.37E-0l 4. 73E-04 3.37E-03 

7.00E+OO 4. 42E-02 3.SlE-OI 4.42E-04 3.S2E-03 

S.OOE+OO 4.l2E-02 4.23E-Ol 4.l2E-04 4. 23E-03 

9.00E+OO 3.SSE-02 4.6lE-Ol 3.SSE-04 4.6lE-03 

1.OOE+Ol 3.S9E-02 4.97E-Ol 3. S9E-04 4.97E-03 

2.00E+Ol 1. 79E-02 7.47E-Ol 1.79E-04 7.47E-03 

3.00E+Ol S.9SE-03 S.72E-Ol S.9SE-OS S.72E-03 

4.00E+Ol 4. 49E-03 9.3SE-Ol 4. 49E-OS 9.3SE-03 

S.OOE+Ol 2.2SE-03 9.66E-Ol 2.2SE-OS 9.66E-03 

6.00E+Ol 1.13E-03 9.S2E-Ol 1. 13E-OS 9.S2E-03 

7.00E+Ol S.6SE-04 9.S9E-Ol S.6SE-06 9.90E-03 

S.OOE+Ol 2.S4E-04 9. 93E-Ol 2.S4E-06 9.94E-03 

9.00E+Ol I. 44E-04 9.9SE-Ol 1. 44E-06 9.9SE-03 

1.OOE+02 7.3SE-OS 9. 96E-Ol 7.3SE-07 9. 97E-03 

2.00E+02 3. 22E-06 9.9SE-Ol 3.22E-OS 9.9SE-03 

3.00E+02 2.7SE-06 9.9SE-Ol 2.7SE-OS 9.9SE-03 

4.00E+02 2. 39E-06 9.9SE-Ol 2.39E-OS 9.9SE-03 

S.OOE+02 2.0SE-06 9.9SE-Ol 2.0SE-OS 9. 99E-03 

6.00E+02 1.SlE-06 9.99E-Ol 1.SlE-OS 9. 99E-03 

7.00E+02 1.SSE-06 9.99E-Ol 1. SSE-OS 9.99E-03 

S.OOE+02 1. 37E-06 9. 99E-Ol 1.37E-OS 9. 99E-03 

9.00E+02 1.20E-06 9. 99E-Ol 1.20E-OS 9. 99E-03 

1.OOE+03 1.04E-06 9. 99E-Ol 1.04E-OS 9. 99E-03 

2.00E+03 2.60E-07 1.OOE+OO O.OOE+OO 1.OOE-02 

3.00E+03 6.SlE-OS 1.OOE+OO O.OOE+OO 1.OOE-02 

4.00E+03 1. 63E-OS 1.OOE+OO O.OOE+OO 1.OOE-02 

B-4i''t 
INGESTION fl= 5.00E-ol STABLE MAGNESIUM 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------~---------------------------~--~------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2. 39E-Ol 7.S5E-Ol 9.94E-Ol 

2.00E-Ol 3. 92E-Ol 5. 82E-Ol 9. 74E-Ol 

3.00E-Ol 4. 35E-Ol 5. 13E-Ol 9.48E-Ol 

4.00E-Ol 4. 39E-Ol 4. 79E-Ol 9.18E-Ol 

5.00E-Ol 4. 33E-Ol 4.5SE-Ol 8. 88E-Ol 

6.00E-Ol 4.26E-Ol 4.32E-Ol 8.S8E-Ol 

7.00E-OI 4.19E-Ol 4.09E-Ol 8.28E-OI 

8.00E-OI 4.14E-Ol 3.8SE-Ol 7.99E-Ol 

9.00E-Ol 4.10E-Ol 3.61E-Ol 7.7lE-Ol 

1.OOE+OO 4.07E-Ol 3.37E-Ol 7.44E-Ol 

2.00E+OO 3. 95E-Ol 1.49E-Ol 5.45E-Ol 

3.00E+OO 3. 92E-Ol 5.89E-02 4.51E-Ol 

4.00E+OO 3. 89E-Ol 2.23E-02 4.12E-Ol 

S.OOE+OO 3. 87E-Ol 8. 29E-03 3. 95E-Ol 

6.00E+OO 3.84E-Ol 3.07E-03 3. 87E-Ol 

7.00E+OO 3.8IE-OI 1.13E-03 3. 83E-Ol 

8.00E+OO 3. 79E-OI 4.16E-04 3.79E-Ol 

9.00E+OO 3.76E-Ol I.S3E-04 3. 76E-Ol 

I.OOE+OI 3. 74E-OI S.64E-OS 3. 74E-OI 

2.00E+OI 3. 49E-Ol O.OOE+OO 3.49E-OI 

3.00E+OI 3.2SE-OI O.OOE+OO 3.2SE-OI 

4.00E+OI 3.03E-Ol O.OOE+OO 3.03E-Ol 

S.OOE+OI 2. 83E-OI O.OOE+OO 2.83E-OI 

6.00E+Ol 2. 64E-OI O.OOE+OO 2. 64E-OI 

7.00E+Ol 2. 46E-OI O.OOE+OO 2. 46E-OI 

8.00E+Ol 2.30E-OI O.OOE+OO 2.30E-OI 

9.00E+OI 2.ISE-OI O.OOE+OO 2.1SE-Ol 

I.OOE+02 2.00E-Ol O.OOE+OO 2.00E-OI 

2.00E+02 1.OOE-Ol O.OOE+OO I.OOE-Ol 

3.00E+02 S.OlE-02 O.OOE+OO S.OIE-02 

4.00E+02 2.S0E-02 O.OOE+OO 2.S0E-02 

S.OOE+02 1.2SE-02 O.OOE+OO 1.2SE-02 

6.00E+02 6. 26E-03 O.OOE+OO 6.26E-03 

7.00E+02 3.13E-03 O.OOE+OO 3.13E-03 

8.00E+02 I.S7E-03 O.OOE+OO 1. 57E-03 

9.00E+02 7.83E-04· O.OOE+OO 7.83E-04 

1.OOE+03 3.92E-04 O.OOE+OO 3.92E-04 

2.00E+03 3. 83E-07 O.OOE+OO 3. 83E-07 

B-47S 
lMGESTION £1= 5 .. 00X-Ql STABLE MAGNESIUK 24 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUHULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 5. 54E-03 5. 44E-04 

2.00E-01 2. 11E-02 4.77E-03 

3.00E-01 3.81E-02 1. 44E-02 

4.00E-01 5. 27E-02 2.90E-02 

5.00E-01 6. 44E-02 4.73E-02 

6.00E-01 7.35E-02 6. 84E-02 

7.00E-01 8.05E-02 9. 11E-02 

8.00E-01 8. 58E-02 1. 15E-01 

9.00E-01 9.00E-02 1. 39E-01 

1.00E+OO 9.32E-02 9. 32E-02 1.6~E-01 1. 63E-01 

2.00E+OO 1. 14E-02 1.0SE-01 1.88E-0l 3.51E-Ol 

3.00E+OO 3. 27E-03 1.0SE-01 9.04E-02 4.4lE-Ol 

4.00E+OO 2. 74E-03 1.11E-01 3.66E-02 4.7SE-01 

5.00E+OO 2. 69E-03 1.13E-01 1.40E-02 4.92E-01 

6.00E+OO 2. 67E-03 1. 16E-01 5. 23E-03 4. 97E-01 

7.00E+OO 2. 65E-03 1.19E-01 1. 94E-03 4. 99E-01 

8.00E+OO 2. 63E-03 1.21E-01 7.14E-04 5.00E-01 

9.00E+OO 2. 62E-03 1. 24E-01 2. 63E-04 S.OOE-01 

1.00E+01 2.60E-03 1.26E-01 9.68E-05 5.00E-01 

2.00E+01 2.42E-03 1.51E-01 O.OOE+OO 5.00E-01 

3.00E+01 2. 26E-03 1.75E-01 O.OOE+OO 5.00E-01 

4.00E+01 2.11E-03 1.97E-01 O.OOE+OO 5.00E-Ol 

5.00E+01 1.97E-03 2. 17E-01 O.OOE+OO 5.00E-01 

6.00E+01 1.S4E-03 2. 36E-01 O.OOE+OO 5.00E-01 

7.00E+Ol 1.7lE-03 2. 54E-01 O.OOE+OO 5.00E-01 

S.OOE+01 1.60E-03 2.70E-01 O.OOE+OO 5.00E-01 

9.00E+01 1. 49E-03 2.S5E-01 O.OOE+OO 5.00E-01 

1.00E+02 1.39E-03 3.00E-01 O.OOE+OO 5.00E-01 

2.00E+02 6.96E-04 4.00E-01 O.OOE+OO 5.00E-01 

3.00E+02 3.4SE-04 4.50E-01 O.OOE+OO 5.00E-01 

4.00E+02 1. 74E-04 4.7SE-01 O.OOE+OO S.OOE-01 

5.00E+02 8.7lE-OS 4.87E-01 O.OOE+OO S.OOE-01 

6.00E+02 4.3SE-OS 4. 94E-01 O.OOE+OO 5.00E-01 

'." . 7.00E+02 2.1SE-05 4.97E-01 O.OOE+OO 5.00E-01 , , 

,', ' ' ' S.OOE+02 1.09E-OS 4.9SE-Ol O.OOE+OO 5.00E-01 

9.00E+02 S.44E-06 4.99E-Ol O.OOE+OO 5.00E-Ol 

1.00E+03 2. 72E-06 5.00E-01 O.OOE+OO S.OOE-01 

B-476 
INGESTION fl= 1.00£-02 STABLE ALUMINIUM 21 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 3.0IE-03 9.96E-OI 9.99E-OI 

2.00E-OI 6.04E-03 9.88E-OI 9. 94E-OI 

3.00E-OI 7. 82E-03 9. 73E-OI 9.8IE-OI 

4.00E-OI 8.80E-03 9.S0E-OI 9.S9E-OI 

S.OOE-OI 9. 33E-03 9.19E-OI 9.29E-Ol 

6.00E-OI 9. 62E-03 8. 83E-Ol 8.92E-Ol 

7.00E-Ol 9.77E-03 8.42E-OI 8.SlE-Ol 

8.00E-Ol 9.8SE-03 7. 98E-Ol 8.08E-Ol 

9.00E-Ol 9.89E-03 7. S2E-Ol 7.62E-Ol 

1.OOE+OO 9.9IE-03 7.06E-Ol 7.l6E-Ol 

2.00E+OO 9. 88E-03 3.20E-OI 3.30E-OI 

3.00E+OO 9.8IE-03 1.27E-OI 1. 37E-OI 

4.00E+OO 9. 74E-03 4. 83E-02 S.80E-02 

S.OOE+OO 9.67E-03 1.80E-02 2.77E-02 

6.00E+OO 9.6lE-03 6. 66E-03 1. 63E-02 

7.00E+OO 9.S4E-03 2. 46E-03 1.20E-02 

8.00E+OO 9.47E-03 9.0SE-04 1.04E-02 

9.00E+OO 9.4lE-03 3. 33E-04 9. 74E-03 

1.OOE+Ol 9. 34E-03 1.23E-04 9.47E-03 

2.UUE+Ol 8. 72E-03 O.OOE+OO 8. 72E-03 

3.00E+Ol 8.l3E-03 O.OOE+OO 8.i3E-03 

4.00E+Ol 7.S9E-03 O.OOE+OO ,7.S9E-03 

S.OOE+Ol 7.08E-03 O.OOE+OO 7.08E-03 

6.00E+OI 6.6IE-03 O.OOE+OO 6.6lE-03 

7.00E+Ol 6.17E-03 O.OOE+OO 6.l7E-03 

8.00E+Ol S.7SE-03 O.OOE+OO S.7SE-03 

9.00E+Ol S.37E-03 O.OOE+OO S.37E-03 

1.OOE+02 S.OlE-03 O.OOE+OO 5.0lE-03 

2.00E+02 2.50E-03 O.OOE+OO 2.50E-03 

3.00E+02 1. 25E-03 O.OOE+OO 1.25E-03 

4.00E+02 6. 26E-04 O.OOE+OO 6.26E-04 

5.00E+02 3.13E-04 O.OOE+OO 3.l3E-04 

6.00E+02 I. 57E-04 O.OOE+OO 1. 57E-04 

7.00E+02 7.83E-05 O.OOE+OO 7. 83E-05 

8.00E+02 3. 92E-OS O.OOE+OO 3. 92E-OS 

9.00E+02 I. 96E-OS O.OOE+OO I. 96E-OS " 1.OOE+03 I,": . ' 9. 79E-06 O.OOE+OO '9. 79E-06 

B-477 
INGESTION f 1= 1.OOE-02 STABLE ALUMINIUM 27 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- -------~---------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED . 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 8. 64E-07 6.09E-04 

2.00E-Ol 4.08E-06 S.89E-03 

3.00E-Ol 8.94E-06 1.93E-02 

4.00E-Ol 1. 47E-OS 4.14E-02 

S.OOE-Ol 2.lOE-OS 7.14E-02 

6.00E-Ol 2. 76E-OS 1.08E-Ol 

7.00E-Ol 3. 43E-OS 1.49E-Ol 

8.00E-Ol 4. lIE-OS 1. 92E-Ol 

9.00E-Ol 4.80E-OS 2.38E-Ol 

1.OOE+OO S.49E-OS S.49E-OS 2. 84E-Ol 2. 84E-Ol 

2.00E+OO 6. 86E-OS 1.24E-04 3.86E-Ol 6.70E-Ol 

3.00E+OO 6. 82E-OS 1. 92E-04 1.93E-Ol 8.63E-oi 

4.00E+OO 6.77E-OS 2. S9E-04 7. 89E-02 9.42E-Ol 

S.OOE+OO 6.73E-OS 3. 27E-04 3.03E-02 9.72E-Ol 

6.00E+OO 6. 68E-OS 3. 94E-04 1.13E-02 9.83E-Ol 

7.00E+OO 6. 63E-05 4.60E-04 4.21E-03 9. 88E-Ol 

8.00E+OO 6.S9E-OS S.26E-04 1. SSE-03 9.89E-Ol. 

9.00E+OO 6.S4E-OS S.91E-04 S.72E-04 9.90E-Ol 

1.OOE+Ol 6.S0E-OS 6. S6E-04 2.10E-04 9.90E-Ol 

2.00E+Ol 6.06E-OS· 1. 28E-03 O.OOE+OO 9.90E-Ol 

3.00E+Ol S.66E-OS 1.87E-03 O.OOE+OO 9.90E-Ol 

4.00E+Ol S.28E-OS 2.41E-03 O.OOE+OO 9.90E-Ol 

S.OOE+Ol 4. 92E-OS 2. 92E-03 O.OOE+OO 9.90E-Ol 

6.00E+Ol 4.S9E-OS' 3. 39E-03 O.OOE+OO 9.90~-Ol 

7.00E+Ol 4.29E-OS 3.83E-03 O.OOE+OO 9.90E-Ol 

8.00E+Ol 4.00E-OS 4.2SE-03 O.OOE+OO 9.90E-Ol 

9.00E+Ol 3.73E-OS 4. 63E-03 O.OOE+OO 9.90E-Ol 

1.OOE+02 3. 48E-OS 4. 99E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 1. 74E-OS 7. SOE-03 O.OOE+OO 9.90E-Ol 

3.00E+02 8.71E-06 8.7SE-03 O.OOE+OO 9.90E-Ol 

4.00E+02 4. 36E-06 9.37E-03 O.OOE+OO 9.90E-Ol 

S.OOE+02 2.18E-06 9. 69E-03 O.OOE+OO 9.90E-Ol 

6.00E+02 1.09E-06 9.84E-03 O.OOE+OO 9.90E-Ol 

7.00E+02 S.4SE-07 9. 92E-03 O.OOE+OO 9.90E-Ol 

'8.00E+02 2.72E-07 9.96E-03 O.OOE+OO 9.90E-Ol 

9.00E+02 1. 36E-07 9. 98E-03 O.OOE+OO 9.90E-Ol 

1.OOE+03 6.81E-08 9.99E-03 O.OOE+OO 9.90E-Ol 

B-478 
INGESTION f l- 1.OOE-02 STABLE SILICON 28 

TIME AFTER FRACTION 'OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 3.00E-03 9. 96E-Ol 9.99E-Ol' 

2.00E-Ol 6.0IE-03 9. 88E-Ol 9. 94E-OI 

3.00E-Ol 7.75E-03 9.73E-Ol 9.8lE-Ol 

4.00E-OI 8. 69E-03 9.50E-Ol 9. 58E-Ol 

5.00E-OI 9.l8E-03 9.19E-Ol 9.28E-0l 

6.00E-OI 9. 42E-03 8.83E-Ol 8. 92E-OI 

7.00E-Ol 9. 52E-03 8. 42E-Ol 8.5IE-OI 

8.00E-OI 9. 55E-03 7. 98E-OI 8.07E-OI 

9.00E-OI 9. 55E-03 7. 52E-OI 7. 62E-OI 

I.OOE+OO 9. 52E-03 7.06E-OI 7.l5E-Ol 

2.00E+OO 9.04E-03 3.20E-OI 3.29E-OI 

3.00E+OO 8.60E-03 1. 27E-OI 1.36E-Ol 

4.00E+OO 8.2IE-03 4.83E-02 5. 65E-02 

5.00E+OO 7. 86E-03 1.80E-02 2. 59E-02 

6.00E+OO 7. 55E-03 6. 66E-03 I.42E-02 

7.00E+OO 7. 28E-03 2.46E-03 9. 74E-03 

8.00E+OO 7.04E-03 9.05E-04 7.94E-03 

9.00E+OO 6. 82E-03 3. 33E-04 7.16E-03 

I.OOE+OI 6. 63E-03 I.23E-04 6.75E-03 

2.00E+Ol 5.49E-03 O.OOE+OO 5. 49E-03 

3.00E+OI 4.94E-03 O.OOE+OO 4.94E-03 

4.00E+OI 4. 57E-03 O.OOE+OO 4. 57E-03 

5.00E+OI 4.25E-03 O.OOE+OO 4.25E-03 

6.00E+OI 3. 97E-03 O.OOE+OO 3. 97E-03 

7.00E+OI 3.70E-03 O.OOE+OO 3.70E-03 

8.00E+OI 3. 45E-03 O.OOE+OO 3. 45E-03 

9.00E+OI 3. 22E-03 O.OOE+OO 3. 22E-03 

I.OOE+02 3.00E-03 O.OOE+OO 3.00E-03 

2.00E+02 I.50E-03 O.OOE+OO I.50E-03 

3.00E+02 7.5IE-04 O.OOE+OO 7.5IE-04 

4.00E+02 3.76E-04 O.OOE+OO 3. 76E-04 

5.00E+02 1. 88E-04 O.OOE+OO 1. 88E-04 

6.00E+02 9.40E-05 O.OOE+OO 9.40E-05 

7.00E+02 4.70E-05 O.OOE+OO 4.70E-05 

8.00E+02 2. 35E-05 O.OOE+OO 2. 35E-05 

9.00E+02 I.I8E-05 O.OOE+OO I.I8E-05 

I.OOE+03 5. 88E-06 O.OOE+OO 5. 88E-06 

B-479 
INGESTION fl'- 1.OOE-02 STABLE SILICON 28 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 7. 42E-06 6.09E-04 

2.00E-:-Ol 3. 49E-OS S.S9E-03 

3.00E-Ol 7. 62E-OS 1.93E-02 

4.00E-Ol 1.2SE-04 4.l4E-02 

S.OOE-Ol 1.77E-04 7.l4E-02 

6.00E-Ol 2. 32E-04 1.OSE-Ol 

7.00E-Ol 2.S6E-04 1. 49E-Ol 

S.OOE-Ol 3.4IE-04 1.92E-Ol 

9.00E-Ol 3. 96E-04 2.3SE-Ol 

1.OOE+OO 4.S0E-04 4.S0E-04 2.S4E-OI 2.S4E-Ol 

2.00E+OO 5.06E-04 9. S6E-04 3. S6E-0l 6.70E-Ol 

3.00E+OO 4. 46E-04 1.40E-03 1. 93E-Ol S.63E-Ol 

4.00E+OO 3. 93E-04 1. 79E-03 7.S9E-02 9.42E-Ol 

S.OOE+OO 3. 47E-04 2.l4E-03 3.03E-02 9. 72E-Ol 

6.00E+OO 3.07E-04 2.4SE-03 1. 13E-02 9.S3E-Ol 

7.00E+OO 2. 72E-04 2.72E-03 4.2lE-03 9.SSE-Ol 

S.OOE+OO 2.4lE-04 2.96E-03 I.SSE-03 9.S9E-Ol 

9.00E+OO 2.lSE-04 3.ISE-03 S.72E-04 9.90E-Ol 

I.OOE+Ol 1~92E-04 3. 37E-03 2.l0E-04 9.90E-Ol 

2.00E+Ol 7.4SE-OS 4.SlE-03 O.OOE+OO 9.90E-Ol 

3.00E+OI 4. 34E-OS S.06E-03 O.OOE+OO 9.90E-Ol 

4.00E+Ol 3.40E-OS S.43E-03 O.OOE+OO 9.90E-Ol S~OOE+OI 3. OlE-OS S.7SE-03 O.OOE+OO 9.90E-Ol 

6.00E+Ol 2.77E-OS 6.03E-03 O.OOE+OO 9.90E-Ol 

7.00E+Ol 2. SSE-OS 6.30E-03 O.OOE+OO 9.90E-Ol 

8.00E+OI 2.40E-OS 6.SSE-03 O.OOE+OO 9.90E-Ol 

9.00E+0l 2. 24E-OS 6.7SE-03 O.OOE+OO 9.90E-Ol 

1.OOE+02 2.09E-OS 7.00E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 I.04E-OS S. SOE-03 O.OOE+OO 9.90E-Ol 

3.00E+02 S.23E-06 9.2SE-03 O.OOE+OO 9.90E-Ol 

4.00E+02 2.6IE-06 9.62E-03 O.OOE+OO 9.90E-Ol 

S.OOE+02 1.3lE-06 9.SIE-03 O.OOE+OO 9.90E-Ol 

6.00E+02 6.S3E-07 9.9lE-03 O.OOE+OO 9.90E-Ol 

7.00E+02 3.27E-07 9.9SE-03 O.OOE+OO 9.90E-Ol . . .. ~ 8.00E+02 1.63E-07 9.9SE-03 O.OOE+OO 9.90E-Ol 

9.00E+02 S.17E-OS 9. 99E-03 O.OOE+OO 9.90E-Ol 

I.OOE+03 4.09E-OS 9.99E-03 O.OOE+OO 9.90E-Ol 

B-4S0 
INGESTION f 1- 8.00£-01 STABLE PHOSPHOR.US 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5. 89E-01 4.03E-01 9.92E-Ol 

2.00E-Ol 7.49E-Ol 2.22E-Ol 9.7lE-01 

3.00E-01 7. 54E-Ol 1.95E-Ol 9.49E-01 

4.00E-Ol 7.40E-01 1.86E-Ol 9.25E-Ol 

5.00E-Ol 7.25E-01 1.77E-01 9.03E-01 

6.00E-01 7. 12E-01 1.68E-01 8.80E-01 

7.00E-0l 7.00E-01 1.59E-01 8.59E-01 

8.00E-Ol 6.89E-Ol 1.49E-01 8.38E-01 

9.00E-Ol 6. 79E-01 1.40E-Ol 8. 19E-01 

1.00E+00 6.70E-01 1.30E-01 8.00E-01 

2.00E+00 6.08E-01 5.70E-02 6.65E-01 

3.00E+00 5. 73E-01 2. 24E-02 5.95E-01 

4.00E+00 5. 48E-01 8.46E-03 5.57E-01 

5.00E+00 5. 29E-01 3. 15E-03 5. 32E-01 

6.00E+00 5. 13E-01 1.l6E-03 5. 14E-Ol 

7.00E+00 4. 99E-01 4. 29E-04 4.99E-Ol 

8.00E+00 4. 86E-Ol 1.58E-04 4.87E-01 

9.00E+00 4. 76E-Ol 5.81E-05 4. 76E-01 

1.00E+01 4. 66E-01 2. 14E-05 4.66E-01 

2.00E+01 3. 93E-01 O.OOE+OO 3.93E-01 

3.00E+01 3. 44E-01 O.OOE+OO 3. 44E-01 

4.00E+01 3.10E-01 O.OOE+OO 3.lOE-01 

5.00E+01 2. 86E-01 O.OOE+OO 2.86E-01 

6.00E+Ol 2. 69E-01 O.OOE+OO 2. 69E-01 

7.00E+01 2. 57E-Ol O.OOE+OO 2. 57E-Ol 

8.00E+01 2. 49E-Ol O.OOE+OO 2.49E-Ol 

9.00E+Ol 2.42E-Ol O.OOE+OO 2.42E-Ol 

1.00E+02 2. 38E-Ol O.OOE+OO 2.38E-Ol 

2.00E+02 2. 19E-Ol O.OOE+OO 2. 19E-01 

3.00E+02 2.09E-Ol O.OOE+OO 2.09E-Ol 

4.00E+02 2.00E-01 O.OOE+OO 2.00E-Ol 

5.00E+02 1.91E-01 O.OOE+OO 1.91E-Ol 

6.00E+02 1.82E-Ol O.OOE+OO 1.82E-Ol 

7.00E+02 1.74E-01 O.OOE+OO 1. 74E-01 

8.00E+02 1. 66E-Ol O.OOE+OO 1.66E-Ol 

9.00E+02 1. 58E-Ol O.OOE+OO 1. 58E-Ol 

1.00E+03 1. 51E-Ol O.OOE+OO 1.51E-Ol 

2.00E+03 9. 53E-02 O.OOE+OO 9.53E-02 

3.00E+03 6.00E-02 O.OOE+OO 6.00E-02 

4.00E+03 3. 78E-02 O.OOE+OO 3. 78E-02 

5.00E+03 2. 38E-02 O.OOE+OO 2. 38E-02 

6.00E+03 1.50E-02 O.OOE+OO 1.50E-02 

7.00E+03 9. 46E-03 O.OOE+OO 9.46E-03 

8.00E+03 5. 96E-03 O.OOE+OO 5. 96E-03 

9.00E+03 3.75E-03 O.OOE+OO 3.75E-03 

1.00E+04 2. 36E-03 O.OOE+OO 2. 36E-03 

2.00E+04 2. 33E-05 O.OOE+OO 2.33E-05 

B-481 
INGESTION fl= 8.00E-ol STABLE PHOSPHORUS 31 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 7.12E-03 1.20E-03 

2.00E-Ol 2.31E-02 5.50E-03 

3.00E-Ol 3. 92E-02 1.22E-02 

4.00E-Ol 5. 39E-02 2.06E-02 

S.OOE-Ol 6.72E-02 3.02E-02 

6.00E-Ol 7.91E-02 4.04E-02 

7.00E-Ol 9.00E-02 5.10E-02 

8.00E-Ol 9. 99E-02 6.18E-02 

9.00E-Ol 1.09E-Ol 7.24E-02 

1.OOE+OO 1.17E-Ol 1.17E-Ol 8. 28E-02 8. 28E-02 

2.00E+OO S.S6E-02 1. 73E-Ol 7.94E-02 1.62E-Ol 

3.00E+OO 3.16E-02 2.04E-Ol 3. 81E-02 2.00E-Ol 

4.00E+OO 2. 23E-02 2.27E-Ol 1.64E-02 2.17E-Ol 

5.00E+OO 1.7SE-02 2.44E-Ol 7. 26E-03 2.24E-Ol 

6.00E+OO 1.4SE-02 2.S9E-Ol 3.60E-03 2. 28E-Ol 

7.00E+OO 1.2SE-02 2.71E-Ol 2.12E-03 2.30E-Ol 

8.00E+OO 1.lOE-02 2.82E-Ol 1.49E-03 2.31E-0l 

9.00E+OO 9.86E-03 2. 92E-Ol 1.20E-03 2. 32E-Ol 

1.OOE+Ol 8.98E-03 3.01E-Ol 1.04E-03 2.33E-Ol 

2.00E+Ol 5. 32E-03 3. 67E-Ol S.91E-04 2.41E-Ol 

3.00E+OI 3. 69E-03 4.lOE-OI 4.10E-04 2. 46E-Ol 

4.00E+Ol 2. 59E-03 4.4IE-Ol 2. 88E-04 2. 49E-OI 

5.00E+Ol I. 83E-03 4.62E-OI 2.03E-04 2.SIE-OI 

6.00E+Ol 1.30E-03 4. 78E-OI 1.44E-04 2. 53E-OI 

7.00E+OI 9. 32E-04 4. 88E-0l I.04E-04 2.S4E-OI 

8.00E+OI 6. 76E-04 4. 96E-OI 7.5IE-05 2.SSE-OI 

9.00E+Ol 4. 98E-04 5.02E-Ol S. S4E-OS 2.S6E-Ol 

1.OOE+02 3.7SE-04 S.06E-Ol 4.17E-OS 2. 56E-OI 

2.00E+02 9. 83E-OS S.23E-OI 1.09E-05 2. S8E-Ol 

3.00E+02 8.71E-05 5. 32E-Ol 9. 68E-06 2.S9E-OI 

4.00E+02 8.30E-05 S.40E-OI 9. 22E-06 2.60E-OI 

5.00E+02 7. 92E-05 S.49E-OI 8.80E-06 2.61E-OI 

6.00E+02 7. 57E-OS 5. S6E-Ol 8.41E-06 2. 62E-OI 

7.00E+02 7.22E-OS S.64E-Ol 8.03E-06 2. 63E-OI 

8.00E+02 6.90E-OS S.71E-Ol 7.66E-06 2.63E-OI 

9.00E+02 6.S9E-05 5. 77E-Ol 7. 32E-06 2. 64E-Ol 

I.OOE+03 6. 29E-05 S.84E-Ol . 6.99E-06 2.6SE-OI ! •. 

2.00E+03 3. 96E-05 6. 34E-OI 4.40E-06 2.70E-OI 

3.00E+03 2.S0E-05 6. 66E-Ol 2.77E-06 2. 74E-OI 

4.00E+03 1.S7E-OS 6. 86E-Ol 1.7SE-06 2. 76E-OI 

5.00E+03 9.9IE-06 6. 99E-Ol l.lOE-06 2.78E-Ol 

6.00E+03 6. 24E-06 7.06E-Ol 6. 94E-07 2. 78E-Ol 

7.00E+03 3. 93E-06 7.liE-OI 4.37E-07 2. 79E-Ol 

8.00E+03 2. 48E-06 7.ISE-OI 2.7SE-07 2. 79E-OI 

9.00E+03 1.S6E-06 7.17E-0l 1. 73E-07 2.80E-Ol 

1.00E+04 9. 83E-07 7.I8E-Ol 1.09E-07 2.80E-Ol 

B-482 
IHGESTION fl= 8.00E-ol BALFLlFE- 1.43E+Ol DAYS PHOSPHORUS 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------~--------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

l.OOE-Ol S.86E-OI 4.0lE-Ol 9. 87E-OI 

2.00E-Ol 7.42E-OI 2.20E-OI 9. 62E-Ol 

3.00E-Ol 7.43E-Ol l.92E-Ol 9.3SE-Ol 

4.00E-Ol 7. 26E-OI 1. 82E-OI 9.08E-Ol 

S.OOE-OI 7.08E-Ol 1. HE-OI 8.8IE-OI 

6.00E-Ol 6. 92E-Ol I.64E-Ol 8.SSE-Ol 

7.00E-Ol 6.77E-Ol 1.S4E-OI 8.30E-Ol 

8.00E-Ol 6. 63E-OI l.44E-OI 8.06E-OI 

9.00E-Ol 6.S0E-Ol 1. 34E-Ol 7. 84E-Ol 

l.OOE+OO 6. 38E-OI 1. 24E-OI 7.62E-Ol 

2.00E+OO S. S2E-OI S.I7E-02 6.04E-OI 

3.00E+OO 4.9SE-OI l.93E-02 S.lSE-OI 

4.00E+OO 4.S2E-Ol 6. 97E-03 4.S8E-OI 

S.OOE+OO 4.lSE-Ol 2. 47E-03 4.l7E-OI 

6.00E+OO 3. 83E-Ol 8.70E-04 3. 84E-Ol 

7.00E+OO 3.SSE-Ol 3.0SE-04 3.SSE-OI 

8.00E+OO 3.30E-Ol I.07E-04 3.30E-0l 

9.00E+OO 3.07E-OI 3. 76E-OS 3. o 7E"';'O 1 

l.OOE+OI 2. 87E-OI 1. 32E-05 2.87E-0l 

2.00E+OI 1. 49E-OI O.OOE+OO l.49E-OI 

3.00E+Ol 8.03E-02 O.OOE+OO 8.03E-02 

4.00E+Ol 4. 46E-02 O.OOE+OO 4. 46E-02 

5.00E+Ol 2.S3E-02 O.OOE+OO 2.S3E-02 

6.00E+OI 1.47E-02 O.OOE+OO 1.47E-02 

7.00E+OI 8.63E-03 O.OOE+OO 8. 63E-03 

8.00E+OI S.l3E-03 O.OOE+OO 5.13E-03 

9.00E+OI 3.08E-03 O.OOE+OO 3.08E-03 

I.OOE+02 1. 86E-03 O.OOE+OO 1. 86E-03 

2.00E+02 1. 34E-05 O.OOE+OO 1. 34E-OS 

3.00E+02 I.OOE-07 O.OOE+OO I.OOE-07 

B-483 
INGESTION f 1- 8.00E...:o1 BALPLIFE- 1.43E+01 DAYS PHOSPHOR.US 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED . 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 7.08E-03 1.19E-03 

2.00E-Ol 2. 29E-02 S.4SE-03 

3.00E-Ol 3. 86E-02 1.2OE-02 

4.00E-Ol S.29E-02 2.02E-02 

5.00E-Ol 6. 55E-02 2.94E-02 

6.00E-Ol 7. 69E-02 3. 93E-02 

7.00E-Ol 8.70E-02 4. 93E-02 

8.00E-Ol 9.6lE-02 S.94E-02 

9.00E-Ol 1.04E-Ol 6. 93E-02 

1.OOE+OO 1.12E-Ol 1.12E-Ol 7. 89E-02 7. 89E-02 

2.OOE+OO S.04E-02 1. 57E-Ol 7.2lE-02 1.47E-Ol 

3.00E+OO 2.73E-02 1. 77E-Ol 3. 29E-02 1. 73E-Ol 

4.00E+OO 1. 83E-02 1.87E-Ol 1. 35E-02 1.78E-0l 

S.OOE+OO 1.37E-02 1. 92E-Ol S.69E-03 1. 76E-Ol 

6.00E+OO 1.09E-02 1.93E-Ol 2. 69E-03 1.70E-Ol 

7.00E+OO 8.90E-03 1. 93E-Ol 1.SlE-03 1. 64E-Ol 

8.00E+OO 7.4SE-03 1.9lE-0l 1.OlE-03 1.57E-Ol 

9.00E+OO 6.37E-03 1. 89E-Ol 7. 72E-04 1.50E-Ol 

1.OOE+Ol 5.53E-03 1.85E-Ol 6.37E-04 1.44E-Ol 

2.00E+Ol 2.02E-03 1. 39E-Ol 2. 24E-04 9.l2E-02 

3.00E+Ol 8.6lE-04 9. 57E-02 9. 57E-OS S.73E-02 

4.00E+Ol 3.72E-04 6. 33E-02 4.l4E-05 3. 58E-02 

5.00l!.+Ol 1.62E-04 4.09E-02 1.80E-OS 2. 22E-02 

6.00E+Ol 7.08E-OS 2.60E-02 7. 86E-06 1. 38E-02 

7.00E+Ol 3.12E-OS 1. 64E-02 3.47E-06 8. S2E-03 

8.00E+Ol 1.40E-05 1.02E-02 1. SSE-06 S.27E-03 

9.00E+Ol 6. 33E-06 6.38E-03 7.04E-07 3.2SE-03 

1.OOE+02 2. 93E-06 3. 96E-03 3. 26E-07 2.00E-03 

B-484 
INGESTION f 1''' 8.00£-01 STABLE SULPHUR 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 5. 36E-Ol 4.03E-Ol 9.39E-Ol 

2.00E-ol 5.90E-Ol 2. 22E-01 8.12E-Ol 

3.00E-Ol 5.03E-ol 1.95E-Ol 6.98E-Ol 

4.00E-01 4. 22E-01 1. 86E-Ol 6.07E-Ol 

5.00E-Ol 3. 58E-01 1.77E-Ol 5.35E-01 

6.00E-Ol 3.09E-01 1. 68E-Ol 4.77E-Ol 

7.00E-Ol 2.72E-01 1.59E-01 4.31E-01 

8.00E-01 2. 44E-Ol 1. 49E-Ol 3. 93E-01 

9.00E-Ol 2. 22E-Ol 1.40E-01 3. 62E-01 

1.00E+00 2.06E-Ol 1.30E-01 3. 36E-01 

2.00E+00 1.55E-01 5.70E-02 2.12E-01 

3.00E+00 1. 49E-01 2. 24E-02 1.71E-01 

4.00E+00 1.45E-01 8. 46E-03 1.53E-01 

5.00E+00 1.41E-01 3. 15E-03 1.44E-01 

6.00PAOO 1. 38E-01 1. 16E-03 1. 39E-01 

7.00E+00 1.34E-Ol 4. 29E-04 1. 35E-01 

8.00E+00 1.31E-Ol 1.58E-04 1.31E-01 

9.00E+OO 1. 28E-01 5. 81E-05 1. 28E-01 

1.00E+01 1. 25E-01 2. 14E-05 1.25E-01 

2.00E+01 9. 99E-02 O.OOE+OO 9. 99E-02 

3.00E+01 8. 21E-02 O.OOE+OO 8. 21E-02 

4.00E+Ol 6. 95E-02 O.OOE+OO .6. 95E-02 

5.00E+Ol 6.06E-02 O.OOE+OO 6.06E-02 

6.00E+01 5. 42E-02 O.OOE+OO 5. 42E-02 

7.00E+Ol 4. 97E-02 O.OOE+OO 4. 97E-02 

8.00E+01 4. 64E-02 O.OOE+OO 4. 64E-02 

9.00E+01 4. 41E-02 O.OOE+OO 4.41E-02 

1.00E+02 4. 24E-02 O.OOE+OO 4. 24E-02 

2.00E+02 3. 74E-02 O.OOE+OO 3. 74E-02 

3.00E+02 3. 61E-02 O.OOE+OO 3. 61E-02 

4.00E+02 3. 48E-02 O.OOE+OO 3. 48E-02 

5.00E+02 3. 36E-02 O.OOE+OO 3. 36E-02 

6.00E+02 3. 25E-02 O.OOE+OO 3.25E-02 

7.00E+02 3. 14E-02 O.OOE+OO 3. 14E-02 

8.00E+02 3.03E-02 O.OOE+OO 3.03E-02 

9.00E+02 2. 93E-02 O.OOE+OO 2. 93E-02 

1.00E+03 2. 83E-02 O.OOE+OO 2. 83E-02 

2.00E+03 2.00E-02 O.OOE+OO 2.00E-02 

3.00E+03 1.41E-02 O.OOE+OO 1.41E-02 

4.00E+03 1.00E-02 O.OOE+OO 1.00E-02 

5.00E+03 7.07E-03 O.OOE+OO 7.07E-03 

6.00E+03 5.00E-03 O.OOE+OO 5.00E-03 

7.00E+03 3. 54E-03 O.OOE+OO 3. 54E-03 

8.00E+03 2.50E-03 O.OOE+OO 2.50E-03 

9.00E+03 1.77E-03 O.OOE+OO 1.77E-03 

1.00E+04 1. 25E-03 8·8OE+00 2.00E+04 3.91E-05 • OE+OO 3:911:8~ 

B-485 
INGESTION f l= 8.00E-ol STABLE SULPHUR 32 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 S.47E-02 6. 49E-03 

2.00E-Ol 1.67E-01 2.lSE-02 

3.00E-Ol 2.6SE-Ol 3. 73E-02 

4.00E-Ol 3.40E-Ol S.2SE-02 

S.OOE-Ol 3.9BE-Ol 6. 69E-02 

6.00E-Ol 4.42E-Ol B.07E-02 

7.00E-Ol 4.7SE-Ol 9.3BE-02 

B.OOE-Ol S.OOE-Ol 1.06E-01 

9.00E-Ol S.20E-Ol 1.lBE-0l 

1.00E+00 S.34E-Ol S.34E-Ol 1. 29E-Ol 1. 29E-Ol 

2.00E+00 4.S7E-02 S.BOE-Ol 7.B3E-02 2.0BE-Ol 

3.00E+00 6.09E-03 S.B6E-Ol 3.S2E-02 2. 43E-Ol 

4.00E+00 3.S0E-03 S.90E-Ol 1.43E-02 2.S7E-Ol 

S.OOE+OO 3. 23E-03 S.93E-Ol S.67E-03 2.63E-Ol 

6.00E+00 3.11E-03 S.96E-Ol 2.33E-03 2.6SE-Ol 

7.00E+00 3.0lE-03 S.99E-Ol 1.07E-03 2. 66E-Ol 

B.OOE+OO 2.9lE-03 6.02E-Ol S.94E-04 2. 67E-Ol 

9.00E+00 2.BlE-03 6.0SE-Ol 4.l2E-04 2. 67E-Ol 

1.00E+Ol 2.7lE-03 6.08E-Ol 3.3BE-04 2. 67E-Ol 

2.00E+Ol 1. 92E-03 6.30E-Ol 2.l4E-04 2.70E-Ol 

3.00E+Ol 1.36E-03 6.46E-Ol 1. SlE-04 2.72E-Ol 

4.00E+Ol 9. 67E-04 6.S7E-Ol 1.07E-04 2. 73E-Ol 

S.OOE+Ol 6.B7E-04 6.6SE-Ol 7.64E-OS 2. 74E-Ol 

6.00E+Ol 4.90E-04 6.71E-Ol S.44E-OS 2.7SE-Ol 

7.00E+Ol 3.S0E-04 6.7SE-Ol 3. B9E-OS 2.7SE-Ol 

B.OOE+Ol 2.SlE-04 6.7BE-Ol 2. 79E-OS 2.7S£-01 

9.00E+Ol 1. BlE-04 6. BOE-Ol 2. OlE-OS 2.76E-Ol 

1.00E+02 1.3lE-04 6.B2E-Ol 1. 46E-OS 2. 76E-Ol 

2.00E+02 1.S4E-OS 6.B6E-Ol 1.71E-06 2.76E-Ol 

3.00E+02 1.14E-OS 6.BBE-Ol 1.26E-06 2. 76E-Ol 

4.00E+02 1.09E-OS 6.B9E-Ol 1.2lE-06 2. 77E-Ol 

S.00E+02 1.OSE-OS 6.90E-Ol 1.17E-06 2. 77E-Ol 

6.00E+02 1. OlE-OS 6.9lE-01 1.13E-06 2.77E-Ol 

B.00E+02 9.46E-06 6.93E-Ol 1.OSE";'06 2.77E-Ol 

9.00E+02 9.l3E-06 6. 94E-Ol 1.01E-06 2.77E-Ol 

1.00E+03 B.B2E-06 6.9SE-Ol 9. BOE-07 2. 77E-Ol 

2.00E+03 6. 24E-06 7.02E-Ol 6. 93E-07 2.7BE-Ol 

3.00E+03 4.4lE-06 7.07E-Ol 4.90E-07 2. 79E-Ol 

4.00E+03 3.l2E-06 7.llE-0l 3.47E-07 2. 79E-Ol 

S.00E+03 2.2lE-06 7.l4E-01 2.4SE-07 2. 79E-Ol 

6.00E+03 1.S6E-06 7.lSE-01 1. 73E-07 2.79E-Ol 

7.00E+03 1.10E-06 7.l7E-01 1.23E-07 2. BOE-Ol 

B.00E+03 7. BOE-07 7.lBE-01 B.67E-OB 2. BOE-Ol 

9.00E+03 S.S2E-07 7.lBE-01 6.13E-OB 2. BOE-Ol 

1.00E+04 3.90E-07 7.l9E-01 4. 34E-OB 2. BOE-Ol 

2.00E+04 1.22E-OB 7.20E-Ol O.OOE+OO 2. BOE-Ol 

B-4B6 
INGESTION £1= 8.00E-01 HALFLIFE= 8.74£+01 DAYS SULPHUR 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol S.3SE-Ol 4.03E-Ol 9.3SE-Ol 

2.00E-Ol S.89E-Ol 2. 22E-Ol 8.llE-Ol 

3.00E-Ol S.02E-Ol 1.94E-Ol 6.96E-Ol 

4.00E-Ol 4.20E-Ol 1.SSE-Ol 6.0SE-Ol 

S.OOE-Ol 3. S6E-Ol 1.77E-Ol S.33E-Ol 

6.00E-Ol 3.0SE-Ol l.6SE-Ol 4.7SE-Ol 

7.00E-Ol 2.71E-0l 1. SSE-Ol 4.29E-Ol 

8.00E-Ol 2.42E-Ol l.48E-Ol 3.91E-Ol 

9.00E-Ol 2.2lE-Ol 1.39E-Ol 3.60E-Ol 

l.OOE+OO 2.0SE-Ol 1.29E-Ol 3.34E-Ol 

2.00E+OO 1. S3E-Ol S.61E-02 2.09E-Ol 

3.00E+OO 1.4SE-Ol 2.l9E-02 l.67E-OI 

4.00E+OO 1.40E-Ol S.19E-03 1.4SE-0l 

5.00E+OO 1. 36E-Ol 3.02E-03 1.39E-Ol 

6.00E+OO 1.31E-Ol l.lIE-03 1.32E-Ol 

7.00E+OO 1.27E-Ol 4.06E-04 1.27E-Ol 

8.00E+OO 1.23E-Ol l.4SE-04 1.23E-Ol 

9.00E+OO 1. 19E-Ol S.41E-OS 1. 19E-Ol 

1.00E+Ol 1.ISE-Ol 1.9SE-OS 1.ISE-Ol 

2.00E+Ol 8.S2E-02 O.OOE+OO 8.52E-02 

3.00E+Ol 6. 48E-02 O.OOE+OO 6. 48E-02 

4.00E+Ol S.06E-02 O.OOE+OO S.06E-02 

5.00E+Ol 4.08E-02 O.OOE+OO 4.08E-02 

6.00E+Ol 3. 37E-02 O.OOE+OO 3. 37E-02 

7.00E+Ol 2.8SE-02 O.OOE+OO 2.8SE-02 

8.00E+Ol 2.46E-02 O.OOE+OO 2. 46E-02 

9.00E+Ol 2.16E-02 O.OOE+OO 2.l6E-02 

1.00E+02 1.92E-02 O.OOE+OO 1.92E-02 

2.00E+02 7.67E-03 O.OOE+OO 7. 67E-03 

3.00E+02 3.34E-03 O.OOE+OO 3. 34E-03 

4.00E+02 1.46E-03 O.OOE+OO 1.46E-03 

S.OOE+02 6. 39E-04 O.OOE+OO 6. 39E-04 

6.00E+02 2. 79E-04 O.OOE+OO 2. 79E-04 

7.00E+02 l.22E-04 O.OOE+OO 1.22E-04 

8.00E+02 S.34E-OS O.OOE+OO S.34E-05 

9.00E+02 2. 33E-OS O.OOE+OO 2. 33E-OS . '. ' 1.00E+03 1.02E-OS O.OOE+OO 1.02E-OS 

B-487 
INGESTION f 1'= 8.00E-ol BALFLIFE= 8.74E+Ol DAYS SULPHUR. 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --~----~----------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol S.47E-02 6.48E-03 

2.00E-Ol 1.66E-Ol 2.14E-02 

3.00E-Ol 2. 64E-Ol 3.72E-02 

4.00E-Ol 3. 39E-Ol S.23E-02 

S.OOE-Ol 3. 96E-Ol 6.67E-02 

6.00E-Ol 4.40E-Ol 8.03E-02 

7.00E-Ol 4.72E-Ol 9.33E-02 

S.OOE-Ol 4.97E-Ol 1.06E-Ol 

9.00E-Ol S.16E-Ol 1.17E-Ol 

1.OOE+OO S.30E-Ol S.30E-Ol 1.28E-Ol 1. 28E-Ol 

2.00E+OO 4.S0E-02 S.7lE-Ol 7.7lE-02 2.04E-Ol 

3.00E+OO S.9SE-03 S.72E-Ol 3. 44E-02 2.37E-Ol 

4.00E+OO 3. 39E-03 S.71E-Ol 1.39E-02 2.49E-Ol 

5.00E+OO 3.1lE-03 S.70E-Ol S.4SE-03 2. 53E-Ol 

6.00E+OO 2.97E-03 5.68E-Ol 2.22E-03 2.S3E-Ol 

7.00E+OO 2.8SE-03 S.67E-Ol 1.OlE-03 2.S2E-Ol 

8.00E+OO 2.73E-03 S.6SE-Ol S.S7E-04 2. SOE-Ol 

9.00E+OO 2.6lE-03 S.63E-Ol 3. 83E-04 2. 49E-Ol 

1.OOE+Ol 2. SIE-03 S.6lE-Ol 3.l2E-04 2.47E-Ol 

2.00E+Ol 1.64E-03 S.38E-Ol 1. 82E-04 2.30E-Ol 

3.00E+Ol 1.07E-03 S.09E-Ol 1.19E-04 2.l4E-Ol 

4.00E+Ol 7.04E-04 4. 79E-Ol 7. 82E-OS 1.99E-Ol 

S.OOE+Ol 4. 62E-04 4. 48E-Ol S.14E-OS 1.84E-Ol 

6.00E+Ol 3.04E-04 4. 17E-Ol 3. 38E-OS 1.7lE-Ol 

7.00E+Ol 2.01E-04 3. 88E-Ol 2. 23E-05 1.S8E-OI 

8.00E+Ol 1.33E-04 3.60E-Ol 1.48E-OS I.46E-Ol 

9.00E+Ol 8. 86E-OS 3. 33E-Ol 9.8SE-06 1.3SE-Ol 

1.00E+02 S.9SE-OS 3.09E-Ol 6.61E-06 1.2SE-Ol 

2.00E+02 3. ISE-06 1.41E-Ol 3.S0E-07 5.66E-02 

3.00E+02 1.OSE-06 6. 38E-02 l.17E-07 2.S6E-02 

4.00E+02 4.S6E-07 2. 89E-02 S.07E-08 1.I6E-02 

S.OOE+02 1.99E-07 l.3lE-02 2.2IE-08 S.25E-03 

6.00E+02 8.7lE-08 5.94E-03 O.OOE+OO 2. 38E-03 

7.00E+02 3.8IE-08 2. 69E-03 O.OOE+OO 1. U8E-03 

8.00E+02 1.67E-08 I.22E-03 O.OOE+OO , 4. 88E-04 

B-488 
INGESTION £1= 1.00E+OO STABLE aILOl.INE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------~------------------------------------------------ SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 9.0SE-OI 9.07E-02 9.96E-Ol 

2.00E-OI 9.8IE-OI 8.23E-03 9. 89E-Ol 

3.00E-OI 9.82E-OI 7.48E-04 9.82E-OI 

4.00E-Ol 9.7SE-Ol 6. 86E-OS 9.7SE-OI 

S.OOE-OI 9.69E-Ol 7.02E-06 9.69E-Ol 

6.00E-OI 9.62E-OI 1. 38E-06 9.62E-OI 

7.00E-OI 9. SSE-Ol 8.30E-07 9.SSE-OI 

8.00E-OI 9.49E-Ol 7.3SE-07 9.49E-Ol 

9.00E-OI 9.42E-OI 6. 83E-07 9.42E-OI 

l.OOE+OO 9.36E-Ol 6.3SE-07 9.36E-Ol 

2.00E+OO 8.73E-OI 2. 76E-07 8. 73E-OI 

3.00E+OO 8. ISE-Ol I.08E-07 8. ISE-Ol 

4.00E+OO 7.60E-Ol 4.09E-08 7.60E-OI 

S.OOE+OO 7.09E-Ol I.S2E-08 7.09E-OI 

6.00E+OO 6. 62E-OI O.OOE+OO 6.62E-Ol 

7.00E+OO 6.I7E-OI O.OOE+OO 6.17E-OI 

8.00E+OO S.76E-OI O.OOE+OO S.76E-OI 

9.00E+OO S.38E-OI O.OOE+OO S.38E-OI 

1.OOE+OI S.02E-OI O.OOE+OO S.02E-Ol 

2.00E+OI 2.SIE-Ol O.OOE+OO 2.S1E-OI 

3.00E+OI 1.2SE-Ol O.OOE+OO 1.2SE-OI 

4.00E+OI 6. 27E-02 O.OOE+OO 6. 27E,,:,,02 

S.OOE+OI 3.14E-02 O.OOE+OO 3.14E-02 

6.00E+OI I.S7E-02 O.OOE+OO I. 57E-02 

7.00E+OI 7. 84E-03 O.OOE+OO 7. 84E-03 

8.00E+OI 3. 92E-03 O.OOE+OO 3.92E-03 

9.00E+OI I.96E-03 O.OOE+OO I.96E-03 

1.OOE+02 9.8IE-04 O.OOE+OO 9.8IE-04 

2.00E+02 9.S9E-07 O.OOE+OO 9. 59E-07 

B-489 
INGESTION f 1:: 1.00E+OO STABLE CHLORINE 35 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------~-----

SYSTEMIC NON-SYSTEMIC 

------------------------- --_.-_-_ ..... _ .......... - 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4.29E-03 4.12E-09 

2.00E-01 1.09E-02 2.1OE-OS 

3.00E-01 1. 77E-02 4. 92E-OS 

4.00E-OI 2. 45E-02 S.57E-OS 

5.00E-OI 3.I3E-02 . I.28E-07 

6.00E-OI 3. 79E-02 1. 73E-07 

7.00E-OI 4.46E-02 2.21E-07 

S.OOE-Ol 5.I2E-02 2. 69E-07 

9.00E-OI 5.77E-02 3.I7E-07 

1.OOE+OO 6.43E-02 6. 43E-02 3. 65E-07 3. 65E-07 

2.00E+OO 6.27E-02 1.27E-01 3.59E-07 7.24E-07 

3.00E+OO 5.S5E-02 1.S5E-Ol 1.6BE-07 8. 92E-07 

4.00E+OO 5.45E-02 2.40E-OI 6.74E-OS 9. 59E-07 

5.00E+OO 5.09E-02 2.91E-OI 2. 57E-08 9.B5E-07 

6.00E+OO 4. 75E-02 3.3BE-01 O.OOE+OO 9. 94E-07 

7.00E+OO 4. 43E-02 3.S3E-01 O.OOE+OO 9.9BE-07 

B.OOE+OO 4.13E-02 4.24E-01 O.OOE+OO 9.99E-07 

9.00E+OO 3.B6E-02 4. 62E-Ol O.OOE+OO 1.OOE-06 

1.OOE+01 3.60E-02 4.9SE-Ol O.OOE+OO I.OOE-06 

2.00E+OI 1.S0E-02 7.49E-01 O.OOE+OO 1.00E-06 

3.00E+OI 9.00E-03 S.75E-Ol O.OOE+OO 1.00E-06 

4.00E+01 4.50E-03 9.37E-01 O.OOE+OO 1.00E-06 

5.00E+Ol 2. 25E-03 9. 69E-01 O.OOE+OO 1.00E-06 

6.00E+01 1.13E-03 9.S4E-Ol O.OOE+OO 1.OOE-06 

7.00E+01 5. 63E-04 9.92E-Ol O.OOE+OO 1.00E-06 

8.00E+Ol 2.B1E-04 9. 96E-Ol O.OOE+OO 1.OOE-06 

9.00E+Ol 1. 41E-04 9.9BE-Ol O.OOE+OO 1.OOE-06 

I.OOE+02 7.04E-05 9.99E-01 O.OOE+OO I 1.OOE-06 

2.00E+02 6. BSE-OB 1.OOE+OO O.OOE+OO 1.00E-06 

B-490 
INGESTION £1= 1.00&+00 BALFLIFE= 1. 10&+08 DAYS CHLOR.INE 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------~-~---------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 9.05E-Ol 9.07E-02 9.96E-Ol 

2.00E-Ol 9.81E-Ol 8. 23E-03 9.89E-Ol 

3.00E-Ol 9. 82E-Ol 7. 48E-04 9. 82E-Ol 

4.00E-Ol 9.75E-Ol 6. 86E-05 9.75E-Ol 

5.00E-Ol 9. 69E-Ol 7.02E-06 9. 69E-Ol 

6.00E-Ol 9. 62E-Ol 1. 38E-06 9.62E-Ol 

7.00E-Ol 9.55E-0l 8.30E-07 9. 53E-Ol 

8.00E-Ol 9.49E-Ol 7.35E-07 9.49E-Ol 

9.00E-Ol 9.42E-Ol 6. 83E-07 9.42E-Ol 

1.00E+00 9. 36E-Ol 6.35E-07 9.36E-Ol 

2.00E+00 8.73E-Ol 2. 76E-07 8.73E-Ol 

3.00E+00 8. 15E-Ol 1.08E-07 8.15E-Ol 

4.00E+00 7.60E-Ol 4.09E-08 7.60E-Ol 

5.00E+00 7.09E-Ol 1. 52E-08 7.09E-Ol 

6.00E+00 6. 62E-Ol O.OOE+OO 6. 62E-Ol 

7.00E+00 6. 17E-Ol O.OOE+OO 6.17E-Ol 

8.00E+00 5.76E-Ol O.OOE+OO 5. 76E-Ol 

9.00E+00 5.38E-Ol O.OOE+OO 5.38E-Ol 

1.00E+Ol 5.02E-Ol O.OOE+oo 5.02E-Ol 

2.00E+Ol 2.51E-Ol O.OOE+OO 2.51E-Ol 

3.00E+Ol 1.25E-Ol O.OOE+OO 1.25E-Ol 

4.00E+Ol 6.27E-02 O.OOE+OO 6.27E-02 

5.00E+Ol 3. 14E-02 O.OOE+OO 3. 14E-02 

6.00E+Ol 1. 57E-02 O.OOE+OO 1. 57E-02 

7.00E+Ol 7. 84E-03 O.OOE+OO 7. 84E-03 

8.00E+Ol 3. 92E-03 O.OOE+OO 3. 92E-03 

9.00E+Ol 1.96E-03 O.OOE+OO 1. 96E-03 

1.00E+02 9.81E-04 O.OOE+OO 9.81E-04 

2.00E+02 9. 59E-07 O.OOE+OO 9. 59E-07 

B-491 
INGESTION f 1= 1.00E+OO .HALFLIPE= 1.10E+08 DAYS CHLORINE 36 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

--------------~---------- ------------~-----~----

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-0l 4. 29E-03 4.12E-09 

2.00E-Ol 1.09E-02 2.lOE-08 

3.00E-OI 1.77E-02 4. 92E-08 

4.00E-OI 2. 45E-02 8. 57E-08 

5.00E-Ol 3. 13E-02 1.28E-07 

6.00E-Ol 3.79E-02 1.73E-07 

7.00E-0l 4. 46E-02 2.21E-07 

S.OOE-OI 5.12E-02 2. 69E-07 

9.00E-OI 5.77E-02 3.17E-07 

1.00E+OO 6.43E-02 6. 43E-02 3.6SE-07 3.6SE-07 

2.00E+OO 6. 27E-02 1. 27E-OI 3.59E-07 7. 24E-07 

3.00E+OO 5.8SE-02 1.85E-01 1.6SE-07 S~92E-07 

4.00E+OO 5.45E-02 r 2.40E-OI 6.74E-OS 9. 59E-07 

5.00E+OO 5.09E-02 2.9IE-OI 2.S7E-OS 9.SSE-07 

6.00E+OO 4.7SE-02 3.3SE-Ol O.OOE+OO 9.94E-07 

7.00E+OO 4. 43E-02 3. 83E-Ol O.OOE+OO 9.9SE-07 

S.OOE+OO 4. 13E-02 4. 24E-Ol O.OOE+OO 9. 99E-07 

9.00E+OO 3.S6E-02 4. 62E-Ol O.OOE+OO 1.00E-06 

I.OOE+01 3.60E-02 4.9SE-Ol O.OOE+OO 1.00E-06 

2.00E+Ol I.SOE-02 7.49E-01 O.OOE+OO 1.00E-06 

3.00E+01 9.00E-03 8. 75E-Ol O.OOE+OO 1.00E-06 

4.00E+Ol 4.50E-03 9. 37E-OI O.OOE+OO 1.00E-06 

5.00E+OI 2. 25E-03 9.69E-Ol O.OOE+OO 1.00E-06 

6.00E+01 1.13E-03 9.S4E-Ol O.OOE+OO 1.OOE-06 

7.00E+Ol 5. 63E-04 9. 92E-Ol O.OOE+OO 1.00E-06 

8.00E+OI 2.S1E-04 9.96E-OI O.OOE+OO 1.00E-06 

9.00E+Ol 1.4IE-04 9. 98E-OI O.OOE+OO I.OOE-06 

I.OOE+02 7.04E-05 9.99E-OI O.OOE+OO 1.00E-06 

2.00E+02 6.8SE-OS I.OOE+OO O.OOE+OO I.OOE-06 

B-492 
INGESTION BI= 1.OOE+OO STABLE POTASSIUM 39 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------~---~-------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 9.0BE-Ol 9.07E-02 9.99E-OI 

2.00E-OI 9.BBE-OI B.23E-03 9. 96E-Ol 

3.00E-OI 9. 93E-Ol 7.4BE-04 9. 94E-Ol 

4.00E-OI 9.92E-Ol 6.B6E-OS 9. 92E-Ol 

5.00E-0l 9.90E-Ol 7.02E-06 9.90E-Ol 

6.00E-Ol 9.B7E-OI 1. 38E-06 9.B7E-OI 

7.00E-Ol 9.SSE-Ol B.30E-07 9. BSE-OI 

B.OOE-Ol 9.B3E-Ol 7.3SE-07 9.B3E-Ol 

9.00E-Ol 9. BOE-OI 6.B3E-07 9. BOE-Ol 

1.OOE+OO 9.7BE-OI 6.3SE-07 9.7BE-Ol 

2.00E+OO 9.S6E-Ol 2.76E-07 9. 56E-Ol 

3.00E+OO 9. 34E-Ol 1.OBE-07 9.34E-Ol 

4.00E+OO 9.13E-OI 4.09E-OB 9.13E-Ol 

5.00E+OO B.92E-Ol I.S2E-OB B.92E-OI 

6.00E+OO B.72E-Ol O.OOE+OO B.72E-OI 

7.00E+OO· B.52E-OI O.OOE+OO B.S2E-Ol 

B.OOE+OO B.33E-Ol O.OOE+OO B.33E-Ol 

9.00E+OO B.14E-Ol O.OOE+OO B.14E-Ol 

1.OOE+OI 7.95E-0l O.OOE+OO 7. 95E-Ol 

2.00E+OI 6. 32E-OI O.OOE+OO 6.32E-OI 

3.00E+Ol 5.02E-Ol O.OOE+OO S.02E-OI 

4.00E+OI 3. 99E-Ol O.OOE+OO 3. 99E-OI 

5.00E+Ol 3.17E-0l O.OOE+OO 3.17E-0l 

6.00E+Ol 2.S2E-Ol O.OOE+OO 2.S2E-OI 

7.00E+Ol 2.00E-OI O.OOE+OO 2.00E-Ol 

B.OOE+Ol 1.S9E-Ol O.OOE+OO 1. 59E-Ol 

9.00E+Ol 1. 26E-OI O.OOE+OO 1.26E-Ol 

I.OOE+02 1.OOE-Ol O.OOE+OO 1.OOE-Ol 

2.00E+02 1.OlE-02 O.OOE+OO 1.OlE-02 

3.00E+02 I.OlE-03 O.OOE+OO I. OlE-03 

4.00E+02 1.OlE-04 O.OOE+OO 1.OlE-04 

S.OOE+02 1. OlE-OS O.OOE+OO 1.OlE-OS 

6.00E+02 1.02E-06 O.OOE+OO 1.02E-06 

7.00E+02 1.02E-07 O.OOE+OO 1.02E-07 

B.OOE+02 1.02E-OB O.OOE+OO 1.02E-OB 

.. 

B-493 
INGESTION fl= 1.00E+OO STABLE POTASSIUM 39 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ---~---------------~~~--------------------------------

SYSTEMIC NON-SYSTEMIC 

------~~-------~--------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 43E-03 4.l2E-09 

2.00E-Ol 3.64E-03 2.lOE-08 

3.00E-01 5. 92E-03 4. 92E-08 

4.00E-01 8.21E-03 8.57E-08 

5.00E-Ol 1.05E-02 1.28E-07 

6.00E-Ol 1.28E-02 1. 73E-07 

7.00E-Ol 1.50E-02 2.2lE-07 

8.00E-Ol 1. 73E-02 2. 69E-07 

9.00E-Ol 1.95E-02 3.l7E-07 

1.OOE+OO 2.l8E-02 2.l8E-02 3. 65E-07 3. 65E-07 

2.00E+OO 2. 22E-02 4.40E-02 3.59E-07 7. 24E-07 

3.00E+OO 2.l7E-02 6. 58E-02 1.68E-07 8. 92E-07 

4.00E+OO 2. 12E-02 8.70E-02 6.74E-08 9. 59E-07 

5.00E+OO 2.08E-02 1.08E-Ol 2. 57E-08 9.85E-07 

6.00E+OO 2.03E-02 1. 28E-01 O.OOE+OO 9. 94E-07 

7.00E+OO 1. 98E-02 1.48E-Ol O.OOE+OO 9. 98E-07 

8.00E+OO 1.94E-02 1.67E-Ol O.OOE+OO 9. 99E-07 

9.00E+OO 1. 89E-02 1. 86E-01 O.OOE+OO 1.00E-06 

1.OOE+Ol 1.85E-02 2.05E-Ol O.OOE+OO 1.OOE-06 

2.00E+Ol 1.47E-02 3. 68E-Ol O.OOE+OO 1.00E-06 

3.00E+Ol 1. 17E-02 4. 98E-Ol O.OOE+OO 1.OOE-06 

4.00E+01 9. 28E-03 6.01E-01 O.OOE+OO 1.00E-06 

5.00E+Ol 7. 37E-03 6. 83E-01 O.OOE+OO 1.00E-06 

6.00E+Ol 5. 86E-03 7.48E-Ol O.OOE+OO 1.00E-06 

7.00E+01 4.66E-03 8.00E-01 O.OOE+OO 1.00E-06 

8.00E+Ol 3.70E-03 8.4lE-Ol O.OOE+OO 1.OOE-06 

9.00E+01 2. 94E-03 8. 74E-01 O.OOE+OO 1.00E-06 

1.OOE+02 2. 33E-03 9.00E-0l O.OOE+OO 1.00E-06 

2.00E+02 2. 34E-04 9.90E-Ol O.OOE+OO 1.OOE-06 

3.00E+02 2. 35E-05 9. 99E-Ol O.OOE+OO 1.OOE-06 

4.00E+02 2.35E-06 1.OOE+OO O.OOE+OO 1.00E-06 

5.00E+02 2. 36E-07 1.00E+OO O.OOE+OO 1.OOE-06 

6.00E+02 2. 37E-08 1.OOE+OO O.OOE+OO 1.00E-06 

B-494 
B-495 
INGESTION' f1= 1.00E+OO HALFLIFE- 4.67E+ll DAYS POTASSIUM 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.43E-03 4. 12E-09 

2.00E-01 3. 64E-03 2.1OE-08 

3.00E-01 5. 92E-03 4. 92E-08 

4.00E-01 8.21E-03 8. 57E-08 

5.00E-01 1.05E-02 1. 28E-07 

6.00E-01 1. 28E-02 1.73E-07 

7.00E-01 1.50E-02 2.21E-07 

8.00E-01 1. 73E-02 2. 69E-07 

9.00E-01 1.95E-02 3. 17E-07 

1.00E+00 2. 18E-02 2. 18E-02 3. 65E-07 3. 65E-07 

2.00E+00 2.22E-02 4.40E-02 3. 59E-07 7. 24E-07 

3.00E+00 2. 17E-02 6. 58E-02 1. 68E-07 8. 92E-07 

4.00E+00 2. 12E-02 8.70E-02 6.74E-08 9. 59E-07 

5.00E+00 2.08E-02 1.08E-01 2. 57E-08 9. 85E-07 

6.00E+00 2.03E-02 1. 28E-01 O.OOE+oo 9. 94E-07 

7.00E+00 1.98E-02 1.48E-Ol O.OOE+OO 9. 98E-07 

8.00E+00 1. 94E-02 1. 67E-01 O.OOE+OO 9.99E-07 

9.00E+00 1. 89E-02 1.86E-01 O.OOE+OO 1.00E-06 

1.00E+01 1.85E-02 2.05E-01 O.OOE+OO 1.00E-06 

2.00E+01 1.47E-02 3. 68E-01 O.OOE+OO 1.00E-06 

3.00E+01 1.17E-02 4. 98E-01 O.OOE+OO 1.00E-06 

4.00E+01 9. 28E-03 6.01E-01 O.OOE+OO 1.00E-06 

5.00E+01 7. 37E-03 6. 83E-01 O.OOE+oo 1.00E-06 

6.00E+01 5. 86E-03 7.48E-01 O.OOE+OO 1.00E-06 

7.00E+01 4. 66E-03 8.00E-01 O.OOE+oo 1.00E-06 

8.00E+01 3.70E-03 8.41E-01 O.OOE+OO 1.00E-06 

9.00E+01 2. 94E-03 8.74E-01 O.OOE+oo 1.00E-06 

1.00E+02 2. 33E-03 9.00E-01 O.OOE+OO 1.00E-06 

2.00E+02 2. 34E-04 9.90E-01 O.OOE+OO 1.00E-06 

3.00E+02 2. 35E-05 9. 99E-01 O.OOE+OO 1.00E-06 

4.00E+02 2. 35E-06 1.00E+00 O.OOE+oo 1.00E-06 

5.00E+02 2. 36E-07 1.00E+00 O.OOE+OO 1.00E-06 

6.00E+02 2. 37E-08 1.00E+00 O.OOE+oo 1.00E-06 

B-496 
INGESTION f 1- 3.00£-01 STABLE CALCIUM 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-OI 1.14E-OI 8.82E-Ol 9. 97E-Ol 

2.00E-Ol 2.l0E-Ol 7. 77E-Ol 9.87E-Ol 

3.00E-OI 2.S4E-Ol 7.19E-Ol 9.72E-Ol 

4.00E-Ol 2.72E-OI 6.80E-OI 9.S2E-Ol 

S.OOE-Ol 2. 79E-OI 6.47E-Ol 9.26E-0l 

6.00E-Ol 2.8lE-Ol 6.l6E-Ol 8.97E-Ol 

7.00E-Ol 2.82E-Ol S.83E-Ol 8.6SE-0l 

8.00E-Ol 2.8lE-OI S.SOE-Ol 8.3IE-Ol 

9.00E-Ol 2.80E-OI S.17E-OI 7.97E-OI 

1.OOE+OO 2. 79E-Ol 4.84E-Ol 7.63E-Ol 

2.00E+OO 2. 69E-Ol 2.16E-0l 4.84E-Ol 

3.00E+OO 2.S9E-Ol 8.S3E-02 3. 44E-Ol 

4.00E+OO 2.S0E-Ol 3. 23E-02 2. 83E-Ol 

S.OOE+OO 2. 42E-Ol 1.20E-02 2.S4E-Ol 

6.00E+OO 2.3SE-Ol 4.4SE-03 2.39E-Ol 

7.00E+OO 2. 28E-Ol 1. 64E-03 2.30E-Ol 

8.00E+OO 2,. 22E-Ol 6.0SE-04 2.23E-Ol 

9.00E+OO 2.l6E-Ol 2. 23E-04 2.l7E,.,;.Ol 

1.OOE+Ol 2.llE-Ol 8.19E-OS 2.llE-Ol 

2.00E+Ol 1.77E-Ol O.OOE+OO 1.77E-Ol 

3.00E+Ol 1.62E-Ol O.OOE+OO 1. 62E-Ol 

4.00E+Ol 1.S4E-Ol O.OOE+OO 1.S4E-Ol 

S.OOE+Ol 1.SOE-OI O.OOE+OO 1.SOE-Ol 

6. GOE+Ol 1.47E-Ol O.OOE+OO 1.47E-Ol 

7.00E+Ol 1.4SE-Ol O.OOE+OO . 1.4SE-OI 

8.00E+Ol 1. 43E-Ol O.OOE+OO 1.43E-OI 

9.00E+OI 1.42E-OI O.OOE+OO 1.42E-OI 

1.OOE+02 1.40E-Ol O.OOE+OO 1.40E-Ol 

2.00E+02 1. 28E-OI O.OOE+OO 1.28E-Ol 

3.00E+02 1.2IE-Ol O.OOE+OO 1.2IE-Ol 

4.00E+02 1.1SE-Ol O.OOE+OO 1.1SE-Ol 

S.OOE+02 1.1IE-OI O.OOE+OO 1.1lE-Ol 

-6. OOE+02· 1.07E-OI O.OOE+OO 1.07E-0l 

7.00E+02 1.04E-OI O.OOE+OO 1.04E-Ol 

8.00E+02 1.OlE-OI O.OOE+OO 1.OIE-OI 

9.00E+02 9.90E-02 O.OOE+OO 9.90E-02 

1.00E+03 9.67E-02 O.OOE+OO 9. 67E-02 

2.00E+03 8.07E-02 O.OOE+OO 8.07E-02 

3.00E+03 6. 99E-02 O.OOE+OO 6.99E-02 

4.00E+03 6.16E-02 O.OOE+OO 6.16E-02 

S.OOE+03 S.49E-02 O.OOE+OO S.49E-02 

7.00E+03 4. 46E-02 O.OOE+OO 4. 46E-02 

8.00E+03 4.06E-02 O.OOE+OO 4.06E-02 

9.00E+03 3.70E-02 . O.OOE+OO 3.70E-02 

I.OOE+04 3.39E-02 .O.OOE+OO 3. 39E-02 

2.00E+04 I.S0E-02 O.OOE+OO I.S0E-02 

B-497 
INGESTION fl= 3.ooE-01 STABLE CALCIUM 40 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-01 1.3lE-03 1. 89E:...03 

2.00E-Ol 3.69E-03 9.05E-OJ 

3.00E-Ol 5. 37E-03 2. 23E-02 

4.00E-Ol 6. 48E-03 4.l6E-02 

5.00E-Ol 7.30E-03 6. 63E-02 

6.00E-Ol 7.99E-03 9.49E-02 

7.00E-Ol 8,. 62E-03 1. 26E-Ol 

8.00E-Ol 9.2lE-03 1.59E-01 

9.00E-Ol 9. 79E-03 1. 93E-Ol 

1.00E+00 1.04E-02 1.04E-02 2. 27E-Ol 2. 27E-Ol 

2.00E+00 5.30E-03 1. 57E-02 2.73E-Ol 5.00E-Ol 

3.00E+00 4. 79E-03 2.05E-02 1.35E-01 6. 35E-Ol 

4.00E+00 4. 37E-03 2. 48E-02 5. 74E-02 6. 92E-Ol 

5.00E+00 4.01E-03 2. 88E-02 2. 43E-02 7.17E-Ol 

6.00E+00 3. 68E-03 3.25E-02 1.13E-02 7. 28E-Ol 

7.00E+00 3. 38E-03 3. 59E-02 6.19E-03 7. 34E-Ol 

8.00E+00 3.10E-03 3.90E-02 4.l4E-03 7. 38E-Ol 

9.00E+00 2. 85E-03 4.l8E-02 3. 23E-03 7. 42E-Ol 

1.00E+Ol 2. 62E-03 4. 45E-02 2.76E-03 7. 44E-OI 

2.00E+Ol 1.15E-03 6.l5E-02 1.15E-03 7.6lE-01 

3.00E+Ol 5. 35E-04 6.92E-02 5. 35E-04 7.69E-Ol 

4.00E+Ol 2. 78E-04 7.29E-02 2. 78E-04 7. 73E-Ol 

5.00E+Ol 1. 68E-04 7.50E-02 1.68E-04 7. 75E-Ol 

6.00E+Ol 1.20E-04 7.64E-02 1.20E-04 7. 76E-Ol 

7.00E+OI 9. 76E-05 7. 75E-02 9. 76E-05 7.77E-Ol 

8.00E+Ol 8.60E-05 7.84E-02 8.60E-05 7.78E-Ol 

9.00E+Ol 7.90E-05 7.92E-02 7.90E-05 7. 79E-Ol 

1.00E+02 7.40E-05 8.00E-02 7.40E-05 7.80E-Ol 

2.00E+02 4. 67E-05 8.58E-02 4. 67E-05 7. 86E-Ol 

3.00E+02 3. 24E-05 8.97E-02 3. 24E-05 7.90E-Ol 

4.00E+02 2.43E-05 9. 25E-02 2. 43E-05 7. 92E-Ol 

5.00E+02 1. 94E-05 9. 46E-02 1. 94E-05 7. 95E-Ol 

6.00E+02 1. 64E-05 9.64E-02 1.64E-05 7.96E-Ol 

7.00E+02 1.43E-05 9.80E-02 1. 43E-05 7.98E-OI 

8.00E+02 1. 28E-05 9. 93E-02 1. 28E-05 7. 99E-OI 

9.00E+02 l.l6E-05 1.OlE-OI 1.16E-05 8.0lE-01 

1.00E+03 1.07E-05 1.02E-0l 1.07E-05 8.02E-OI 

2.00E+03 6. 29E-06 I.lOE-Ol 6. 29E-06 8.lDE-01 

3.00E+03 4. 67E-06 1.15E-01 4. 67E-06 8.l5E-01 

4.00E+03 3. 72E-06 I.19E-01 3. 72E-06 8.19E-Ol 

5.00E+03 3.05E-06 1.23E-01 3.05E-06 8. 23E-Ol 

7.00E+03 2.18E-06 1. 28E-0l 2.l8E-06 8. 28E-Ol 

8.00E+03 1. 89E-06 1.30E-01 I.89E-06 8.30E-Ol 

9.00E+03 l.66E-06 I.3IE-OI 1. 66E-06 8.3IE-Ol 

1.00E+04 1. 47E-06 1.33E-Ol 1. 47E-06 8. 33E-Ol 

2.00E+04 5. 94E-07 1. 42E-Ol 5. 94E-07 8. 42E-Ol 

B-498 
INGESTION f1= 3.00E-ol BALFLIFE- 1.63B+02 DAYS CALCIUM 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------~------------------------------------------------ SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI I.I4E-OI S.S2E-OI 9.96E-OI 

2.00E-OI 2.lOE-OI 7.77E-OI 9.S6E-OI 

3.00E-OI 2. 53E-OI 7. ISE-OI 9.7lE-OI 

4.00E-OI 2.7IE-OI 6. 79E-OI 9.50E-OI 

S.OOE-OI 2.7SE-OI 6.46E-OI 9. 24E-OI 

6.00E-OI 2.SIE-OI 6.14E-OI S.95E-OI 

7.00E-OI 2.SIE-OI 5.B2E-OI B.63E-0l 

S.OOE-OI 2.S0E-OI 5.49E-OI B.29E-OI 

9.00E-OI 2. 79E-OI S.I5E-OI 7. 94E-OI 

I.OOE+OO 2.7SE-OI 4.SIE-OI 7. 59E-OI 

2.00E+OO 2.66E-OI 2.14E-OI 4.S0E-OI 

3.00E+OO 2. 56E-OI S.43E-02 3.40E-OI 

4.00E+OO 2. 46E-OI 3. ISE-02 2.7BE-OI 

S.OOE+OO 2. 37E-OI 1. ISE-02 2. 49E-OI 

6.00E+OO 2. 29E-OI 4. 34E-03 2. 33E-OI 

7.00E+OO 2. 22E-OI I.S9E-03 2. 23E-OI 

S.OOE+OO 2. ISE-OI S.S5E-04 2.15E-OI 

9.00E+OO 2.0SE-OI 2.14E-04 2.0SE-OI 

I.OOE+OI 2.02E-OI 7.S5E-05 2.02E-OI 

2.00E+OI 1. 63E-OI O.OOE+OO 1. 63E-OI 

3.00E+OI I.42E-OI O.OOE+OO I.42E-OI 

4.00E+OI I.30E-OI O.OOE+OO I.30E-OI 

S.OOE+OI I.2IE-OI O.OOE+OO I.2IE-0l 

6.00E+OI I.I4E-OI O.OOE+OO I.I4E-OI 

7.00E+OI I.OSE-OI O.OOE+OO I.OBE-OI 

B.OOE+OI I.02E-OI O.OOE+OO I.02E-OI 

9.00E+OI 9. 66E-02 O.OOE+OO 9. 66E-02 

I.OOE+02 9.16E-02 O.OOE+OO 9.16E-02 

2.00E+02 S.4SE-02 O.OOE+OO 5.4BE-02 

3.00E+02 3. 37E-02 O.OOE+OO 3. 37E-02 

4.00E+02 2. IOE-02 O.OOE+OO 2.lOE-02 

S.OOE+02 1. 32E-02 O.OOE+OO 1. 32E-02 

6.00E+02 S.3SE-03 O.OOE+OO S.35E-03 

7.00E+02 5.30E-03 O.OOE+OO 5.30E-03 

S.OOE+02 3.3SE-03 O.OOE+OO 3.3SE-03 

9.00E+02 2. ISE-03 O.OOE+OO 2.15E-03 

I.OOE+03 I.3SE-03 O.OOE+OO I.3BE-03 

2.00E+03 1. 63E-OS O.OOE+OO 1. 63E-OS 

3.00E+03 2.02E-07 O.OOE+OO 2.02E-07 

B-499 
INGESTION £1= 3.00E-ol HALPLIP'E= 1.63E+02 DAYS CALCIUM 45 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE. ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATE 

D.t\YS URINE URINE FECES FECES 

1. 00E-01 1.31E-03 1.89E-03 

2.00E-Ol 3. 68E-03 9.04E-03 

3.00E-01 5.36E-03 2. 22E-02 

4.00E-01 6.47E-03 4. 16E-02 

5.00E-01 7.28E-03 6. 61E-02 

6.00E-Ol 7.97E-03 9.47E-02 

7.00E-01 8. 59E-03 1.26E-01 

/).00E:-01 9. 18E-03 1.59E-01 

9.00E-Ol 9.75E-03 1.92E-01 

1.00E+00 1.03E-02 1.03E-02 2.26E-01 2.26E-Ol 

2.00E+00 5.26E-03 1.55E-02 2.71E-0l 4.96E-Ol 

3.00E+00 4.73E-03 2.02E-02 1.33E-Ol 6.27E-01 

4.00E+00 4.30E-03 2.44E-02 5. 64E-02 6.81E-Ol 

5.00E+00 3.92E-03 2. 82E-02 2. 38E-02 7.02E-01 

6.00E+00 3.58E-03 3.17E-02 1.1OE-02 7.10E-Ol 

7.00E+00 3.28E-03 3.48E-02 6.0lE-03 7.13E-01 

8.00E+00 3.00E-03 3.77E-02 4.00E-03 7.14E-01 

9.00E+00 2. 74E-03 4.03E-02 3. 11E-03 7.14E-Ol 

1.00E+01 2.5lE-03 4. 26E-02 2.64E-03 7. 13E-01 

2.00E+01 1.05E-03 5.65E-02 1.05E-03 6.99E-01 

3.00E+Ol 4.71E-04 6.09E-02 4.71E-04 6.77E-01 

4.00E+01 2.34E-04 6.15E-02 2.34E-04 6.52E-Ol 

5.00E+Ol 1.36E-04 6.07E-02 1.36E-04 6.27E-01 

6.00E+Ol 9.30E-05 5. 92E-02 9.30E-05 6.02E-Ol 

7.00E+01 7.25E-05 5.75E-02 7.25E-05 5.77E-01 

8.00E+01 6. 12E-05 5. 58E-02 6. 12E-05 5.54E-01 

9.00E+01 5.39E-05 5.40E-02 5.39E-05 5.31E-Ol 

1.00E+02 4. 84E-05 5.23E-02 4. 84E-05 5.1OE-Ol 

2.00E+02 2.00E-05 3.67E-02 2.00E-OS 3.36E-01 

3.00E+02 9.05E-06 2.50E-02 9.05E-06 2.21E-Ol 

4.00E+02 4.43E-06 1.69E-02 4.43E-06 1.45E-01 

5.00E+02 2.32E-06 1.13E-02 2. 32E-06 9. 48E-02 

6.00E+02 1.28E-06 7.52E-03 1.28E-06 6.21E-02 

7.00E+02 7.28E-07 4.99E-03 7.28E-07 4.07E-02 

8.00E+02 4.2SE-07 3.31E-03 4.2SE-07 2.66E-02 

9.00E+02 2.52E-07 2.19E-03 2.S2E-07 1.74E-02 

1.00E+03 1.52E-07 1. 45E-03 1.52E-07 1.14E~02 

B-500 
INGESTION £1= 3.00£-01 BA.LFLIFE- 4.53E+OO DAYS CALCIUM 47 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS tRACT BODY 

1.00E-01 1. 13E-Ol 8. 69E-Ol 9. 82E-Ol 

2.00E-01 2.04E-01 7. 54E-Ol 9. 58E-01 

3.00E-Ol 2. 42E-Ol 6. 86E-Ol 9. 29E-01 

4.00E-01 2. 56E-01 6.40E-01 8. 95E-01 

5.00E-01 2. 58E-OI 6.00E-01 8. 58E-01 

6.00E-01 2.57E-01 5. 62E-01 8. 18E-Ol 

7.00E-01 2. 53E-01 5.24E-01 7. 77E-01 

8.00E-01 2. 49E-Ol 4.87E-01 7. 36E-01 

9.00E-01 2. 44E-01 4.50E-Ol 6. 95E-01 

1.00E+OO 2.40E-01 4. 15E-01 .6.54E-01 

2.00E+00 1. 98E-01 1.59E-01 3. 57E-01 

3.00E+00 1.64E-01 5. 39E-02 2. 18E-01 

4.00E+00 1.36E-01 1. 75E-02 I.53E-01 

5.00E+00 1.13E-01 5.60E-03 1. 18E-Ol 

6.00E+00 9. 38E-02 1. 78E-03 9. 56E-02 

7.00E+00 7. 82E-02 5. 63E-04 7. 88E-02 

8.00E+00 6. 53E-02 1.78E-04 6. 55E-02 

9.00E+00 5. 46E-02 5. 62E-05 5. 46E-02 

1.00E+01 4.57E-02 1.77E-05 4. 57E-02 

2.00E+01 8.30E-03 O.OOE+OO 8.30E-03 

3.00E+Ol 1. 64E-03 O.OOE+OO 1. 64E-03 

4.00E+Ol 3. 39E-04 O.OOE+OO 3. 39E-04 

5.00E+01 7.13E-05 O.OOE+OO 7. 13E-05 

6.00E+01 1. 52E-05 O.OOE+OO 1. 52E-05 

7.00E+Ol 3. 23E-06 O.OOE+OO 3. 23E-06 

8.00E+01 6.92E-07 O.OOE+OO 6. 92E-07 

9.00E+Ol 1. 48E-07 O.OOE+OO 1.48E-07 

1.00E+02 3. 17E-08 O.OOE+OO 3. 17E-08 

B-501 
INGESTION f 1- 3.00£-01 BALFLln... 4.53£+00 DAYS CALCIDK 47 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

I.OOE-OI I.29E-03 1. 87E-03 

2.00E-OI 3.S7E-03 8.78E-03 

3.00E-OI S.l3E-03 2.13E-02 

4.00E-OI 6.09E-03 3. 92E-02 

S.OOE-OI 6.76E-03 6.14E-02 

6.00E-OI 7. 29E-03 8.66E-02 

7.00E-OI 7. 74E-03 I.l3E-OI 

8.00E-OI S.ISE-03 I.4IE-OI 

9.00E-OI S. S3E-03 I.68E-OI 

I.OOE+OO 8. 89E-03 S.89E-03 1.9SE-OI 1.9SE-OI 

2.00E+OO 3.90E-03 1. ISE-02 2.01E-0l 3.68E-OI 

3.00E+OO 3.03E-03 1.29E-02 8.S4E-02 4.0IE-OI 

4.00E+OO 2. 37E-03 I.3SE-02 3.11E-02 3.7SE-0l 

S.OOE+OO I.S6E-03 1. 34E-02 I.l3E-02 3. 34E-OI 

6.00E+OO I.47E-03 1.30E-02 4. SOE-03 2.91E-OI 

7.00E+OO 1.I6E-03 1. 23E-02 2.l2E-03 2.S2E-OI 

8.00E+OO 9.12E-04 I. ISE-02 I.22E-03 2.17E-0l 

9.00E+OO 7.l9E-04 I.06E-02 8. ISE-04 I. 87E-OI 

1.OOE+OI S.67E-04 9. 62E-03 S.97E-04 1.6IE-OI 

2.00E+OI S.38E-OS 2.8SE-03 S.38E-OS 3.S7E-02 

3.00E+OI S.43E-06 7.02E-04 S.43E-06 7.8lE-03 

4.00E+Ol 6.l0E-07 1.60E-04 6.lOE-07 1.70E-03 

5.00E+0l 8.00E-08 3.S7E-05 8.00E-OS 3. 69E-04 

6.00E+OI I. 24E-OS 7. 87E-06 1. 24E-08 8.00E-05 

B-502 
INGESTION fI== I.OOE-02 STABLE TITANIUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------~-------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 3.01E-03 9.96E-Ol 9. 99E-Ol 

2.00E-Ol 6.05E-03 9.BBE-Ol 9.94E-Ol 

3.00E-Ol 7.B3E-03 9.73E-Ol 9.BIE-Ol 

4.00E-Ol B.81E-03 9.50E-Ol 9. 59E-Ol 

5.00E-Ol 9.35E-03 9.19E-Ol 9.29E-Ol 

6.00E-Ol 9.64E-03 8.B3E-Ol B.92E-Ol 

7.00E-Ol 9.BOE-03 B.42E-Ol B.51E-Ol 

B.OOE-Ol 9.B9E-03 7.9BE-Ol B.OBE-Ol 

9 •. 00E-Ol 9. 93E-03 7.52E-Ol 7.62E-Ol 

1.OOE+OO 9.96E-03 7.06E-Ol 7.16E-Ol 

2.00E+OO 9.9BE-03 3.20E-Ol 3.30E-Ol 

3.00E+OO 9.97E-03 1.27E-Ol 1.37E-Ol 

4.00E+OO 9. 96E-03 4.B3E-02 5.B3E-02 

5.00E+OO 9. 94E-03 1. BOE-02 2. BOE-02 

6.00E+OO 9. 93E-03 6. 66E-03 1. 66E-02 

7.00E+OO 9.92E-03 2. 46E-03 1.24E-02 

B.OOE+OO 9.91E-03 9.05E-04 1.OBE-02 

9.00E+OO 9.90E-03 3. 33E-04 1.02E-02 

1.OOE+Ol 9.B9E-03 1.23E-04 1.OOE-02 

2.00E+Ol 9.77E-03 O.OOE+OO 9.77E-03 

3.00E+Ol 9. 66E-03 O.OOE+OO 9. 66E-03 

4.00E+Ol 9. 55E-03 O.OOE+OO 9.55E-03 

5.00E+Ol 9. 44E-03 O.OOE+OO 9.44E-03 

6.00E+Ol 9.33E-03 O.OOE+OO 9. 33E-03 

7.00E+Ol 9. 23E-03 O.OOE+OO 9.23E-03 

B.OOE+Ol 9.12E-03 O.OOE+OO 9.12E-03 

9.00E+Ol 9.01E-03 O.OOE+OO 9.01E-03 

1.OOE+02 B.91E-03 O.OOE+OO B.91E-03 

2.00E+02 7. 94E-03 O.OOE+OO 7.94E-03 

3.00E+02 7.07E-03 O.OOE+OO 7.07E-03 

4.00E+02 6.30E-03 ci.OOE+OO 6.30E-03 

5.00E+02 5.61E-03 O.OOE+OO 5.61E-03 

6.00E+02 5.00E-03 O.OOE+OO 5.00E-03 

7.00E+02 4.46E-03 O.OOE+OO 4.46E-03 

B.OOE+02 3. 97E-03 O.OOE+OO 3. 97E-03 

9.00E+02 3. 54E-03 O.OOE+OO 3. 54E-03 

1.OOE+03 3.15E-03 O.OOE+OO 3.15E-03 

2.00E+03 9. 93E-04 O.OOE+OO 9. 93E-04 

3.00E+03 3.13E-04 O.OOE+OO 3.13E-04 

4.00E+03 9.B6E-05 O.OOE+OO 9.B6E-05 

5.00E+03 3.lOE-05 O.OOE+OO 3.10E-05 

6.00E+03 9.7BE-06 O.OOE+OO 9.7BE-06 

7.00E+03 3.0BE-06 O.OOE+OO 3.0BE-06 

B.OOE+03 9.71E-07 O.OOE+OO 9.71E-07 

9.00E+03 3.06E-07 O.OOE+OO 3.06E-07 

1.OOE+04 9. 64E-OB O.OOE+OO 9. 64E-OB 

B-503 
INGESTION fl= 1.00E-Q2 STABLE TITANIUM 48 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------~------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA . FECES FECES 

1.OOE-Ol 1.44E-07 6.09E-04' 

2.00E-Ol 6.S0E-07 5.S9E-03 

3.00E-Ol 1.49E-06 1.93E-02 

4.00E-Ol 2.46E-06 4.l4E-02 

5.00E-Ol 3.5IE-06 7.l4E-02 

6.00E-Ol 4.6lE-06 1.OSE-Ol 

7.00E-Ol 5. 73E-06 1.49E-Ol 

S.OOE-Ol 6.S7E-06 1.92E-Ol 

9.00E-Ol 8.02E-06 2.3SE-Ol 

1.OOE+OO 9.l6E-06 9.l6E-06 2.S4E-Ol 2.S4E-Ol 

2.00E+OO 1.15E-05 2.07E-05 3.S6E-Ol 6.70E-Ol 

3.00E+00 1.15E-05 3. 22E-05 1. 93E-Ol S.63E-Ol 

4.00E+OO 1.15E-05 4. 37E-05 7.S9E-02 9.42E-Ol 

5.00E+OO 1.15E-05 5. 52E-05 3.03E-02 9. 72E-Ol 

6.00E+OO 1.15E-05 6.67E-05 1.13E-02 9.83E-Ol 

7.00E+00 1.15E-05 7.S2E-05 4.2lE-03 9.SSE-Ol 

S.OOE+OO 1.15E-05 8.96E-05 1. 55E-03 9.S9E-Ol 

9.00E+OO 1.14E-05 1.01E-04 5. 72E-04 9.90E-Ol 

1.OOE+Ol 1.14E-05 1.12E-04 2.l0E-04 9.90E-Ol 

2.00E+Ol 1.BE-05 2. 26E-04 O.OOE+OO 9.90E-Ol 

3.00E+Ol 1.l2E-05 3.3SE-04 O.OOE+OO 9.90E-Ol 

4.00E+Ol 1.lOE-05 4. 49E-04 O.OOE+OO 9.90E-Ol 

5.00E+Ol 1.09E-05 5.59E-04 O.OOE+OO 9.90E-Ol 

6.00E+Ol 1.OSE-05 6. 67E-04 O.OOE+OO 9.90E-Ol 

7.00E+Ol 1.07E-05 7.74E-04 O.OOE+OO 9.90E-Ol 

8.00E+Ol 1.05E-05 8.80E-04 O.OOE+OO 9.90E-Ol 

9.00E+Ol 1.04E-05 9. S5E-04 O.OOE+OO 9.90E-Ol 

1.OOE+02 1.03E-05 1.09E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 9.lSE-06 2.06E-03 O.OOE+OO 9.90E-Ol 

3.00E+02 S.17E-06 2. 93E-03 O.OOE+OO 9.90E-Ol 

4.00E+02 7.2SE-06 3.70E-03 O.OOE+OO 9.90E-Ol 

5.00E+02 6.49E-06 4. 39E-03 O.OOE+OO 9.90E-Ol 

6.00E+02 5.7SE-06 5.00E-03 O.OOE+OO 9.90E-OI 

7.00E+02 5.15E-06 5. 54E-03 O.OOE+OO 9.90E-OI 

S.00E+02 4. 59E-06 6.03E-03 O.OOE+OO 9.90E-OI 

9.00E+02 4.09E-06 6. 46E-03 O.OOE+OO 9.90E-OI 

1.00E+03 3. 64E-06 6. 85E-03 O.OOE+OO 9.90E-OI 

2.00E+03 1.15E-06 9.0IE-03 O.OOE+OO 9.90E-OI 

3.00E+03 3.6lE-07 9. 69E-03 O.OOE+OO 9.90E-OI 

4.00E+03 1.14E-07 9.90E-03 O.OOE+OO 9.90E-Ol 

5.00E+03 3. 59E-08 9. 97E-03 O.OOE+OO 9.90E-OI 

6.00E+03 1.l3E-08 9. 99E-03 O.OOE+OO 9.90E-OI 

8-504 
INGESTION £1= 1.00£-02 BALFum,.. 3.30£+02 DAYS VANADIUM. 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------~------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 2. 78E-03 9.96E-Ol 9. 99E-01 

2.00E-Ol 5.08E-03 9.88E-Ol 9. 93E-Ol 

3.00E-01 5.90E-03 9.72E-Ol 9. 78E-Ol 

4.00E-Ol 5. 93E-03 9.49E-01 9.55E-01 

5.00E-01 5.62E-03 9. 18E-01 9. 24E-Ol 

6.00E-Ol 5.20E-03 8. 82E-01 8. 87E-Ol 

7.00E-01 4. 78E-03 8.40E-01 8.45E-Ol 

8.00E-Ol 4. 42E-03 7. 96E-Ol 8.01E-Ol 

9.00E-01 4. 11E-03 7. 51E-Ol 7. 55E":,,,01 

1.00E+00 3. 86E-03 7.04E-Ol 7.08E-Ol 

2.00E+00 3.04E-03 3. 19E-01 3.22E-01 

3.00E+00 2. 98E-03 1.26E-01 1.29E-01 

4.00E+00 2. 97E-03 4. 79E-02 5.09E-02 

5.00E+00 2. 97E-03 1. 78E-02 2.08E-02 

6.00E+00 2. 96E-03 6. 58E-03 9. 54E-03 

7.00E+00 2. 95E-03 2. 42E-03 5. 38E-03 

8.00E+00 2. 95E-03 8.90E-04 3. 84E-03 

9.00E+00 2. 94E-03 3. 27E-04 3.27E-03 

1.00E+01 2.94E-03 1.20E-04 3.06E-03 

2.00E+01 2. 87E-03 O.OOE+OO 2. 87E-03 

3.00E+01 2.81E-03 O.OOE+OO 2.8lE-03 

4.00E+Ol 2. 75E-03 O.OOE+OO 2. 75E-03 

5.00E+Ol 2. 69E-03 O.OOE+OO 2. 69E-03 

6.00E+01 2. 63E-03 O.OOE+OO 2. 63E-03 

7.00E+01 2. 58E-03 O.OOE+OO 2. 58E-03 

8.00E+01 2. 52E-03 O.OOE+OO 2. 52E-03 

9.00E+01 2.47E-03 O.OOE+OO 2.47E-03 

1.00E+02 2.41E-03 O.OOE+OO 2. 41E-03 

2.00E+02 1.94E-03 O.OOE+OO 1. 94E-03 

3.00E+02 1. 56E-03 O.OOE+OO 1. 56E-03 

4.00E+02 1.26E-03 O.OOE+OO 1. 26E-03 

5.00E+02 1.01E-03 O.OOE+OO 1.01E-03 

6.00E+02 8.16E-04 O.OOE:l-OO 8. 16E-04 

7.00E+02 6. 57E-04 O.OOE+OO 6.57E-04 

8.00E+02 5. 29E-04 O.OOE+OO 5.29E-04 

9 .. 00E+02 4. 26E-04 O.OOE+OO 4. 26E-04 < , 1.00E+03 3. 43E-04 O.OOE+OO 3. 43E-04 

2.00E+03 3.91E-05 O.OOE+OO 3. 91E-05 

3.00E+03 4.47E-06 O.OOE+OO 4. 47E-06 

4.00E+03 ' 5.10E-07 O.OOE+OO 5.10E-07 

5.00E+03 5. 83E-08 O.OOE+OO 5. 83E-08 

B-505 
INGESTION f l- 1.OOE-02 HALFLlFEm 3.30E+02 DAYS V~DIUK 49 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- -------------------~--- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.24E-04 6.09E-04 

2.00E-Ol 9.6BE-04 S.B9E-03 

3.00E-0l 1.93E-03 1. 93E-02 

4.00E-O! 2.BBE-03 4.l4E-02 

S.OOE-Ol 3. 73E-03 7.l3E-02 

6.00E-Ol 4. 44E-03 1.OBE-Ol 

7.00E-Ol S.OIE-03 1.4SE-0l 

B.OOE-Ol S.46E-03 1.92E-Ol 

9.00E-Ol S.B2E-03 2.3BE-Ol 

1.OOE+OO 6.09E-03 6.09E-03 2.B4E-Ol 2.B4E-OI 

2.00E+OO B.34E-04 6.9IE-03 3.B4E-Ol 6.67E-Ol 

3.00E+OO S.3SE-OS 6.9SE-03 1.9lE-Ol B.S7E-Ol 

4.00E+OO 3.S4E-06 6. 94E-03 7.B3E-02 9. 34E-Ol 

S.OOE+OO 4.l4E-07 6. 93E-03 3.00E-02 9. 62E-Ol 

6.00E+OO 2.lBE-07 6.9lE-03 1.12E-02 9.7lE-0l 

7.00E+OO 2.06E-07 6.90E-03 4.l4E-03 9. 73E-Ol 

B.OOE+OO 2.04E-07 6. BSE-03 1.S3E-03 9. 73E-Ol 

9.00E+OO 2.04E-O} 6.B7E-03 S.6lE-04 9.7lE-OI 

1.OOE+Ol 2.03E-07 6. 86E-03 2.06E-04 9. 69E-Ol 

2.00E+Ol 1. 99E-07 6.72E-03 O.OOE+OO 9. 49E-Ol 

3.00E+Ol 1.9SE-07 6.SBE-03 O.OOE+OO 9.30E-Ol 

4.00E+Ol 1.9lE-07 6.44E-03 O.OOE+OO 9.lOE-Ol 

S.OOE+Ol 1.B7E-07 6.3lE-03 O.OOE+OO B.9lE-0l 

6.00E+Ol 1.83E-07 6.l8E-03 O.OOE+OO S.73E-Ol 

7.00E+Ol 1. 79E-07 6.06E-03 O.OOE+OO 8.SSE-Ol 

8.00E+Ol 1.7SE-07 S.93E-03 O~OOE+OO S.37E-Ol 

9.00E+Ol 1.11E-07 S.BlE-03 O.OOE+OO S.19E-Ol 

I.OOE+02 1. 67E-07 S.69E-03 O.OOE+OO B.OlE-Ol 

2.00E+02 1.3SE-07 4. 63E-03 O.OOE+OO 6.50E-Ol 

3.00E+02 1.OBE-07 3. 76E-03 O.OOE+OO S.27E-Ol 

4.00E+02 B.73E-OS 3.06E-03 O.OOE+OO 4.27E-Ol 

S.OOE+02 7.03E-OS 2. 48E-03 O.OOE+OO 3. 46E-Ol 

6.00E+02 S.66E-OS 2.02E-03 O.OOE+OO 2.SlE-Ol 

7.00E+02 4. SSE-OS 1. 64E-03 O.OOE+OO 2.2BE-Ol 

8.00E+02 3. 66E-OS 1.33E-03 O.OOE+OO 1.84E-Ol 

9.00E+02 2.9SE-OB 1.OSE-Q3 O.OOE+OO 1.50E-Ol 

1.OOE+03 2. 37E-OB S.BlE-04 O.OOE+OO 1.2lE-Ol 

B-S06 
INGESTION f 1 == 1.00E-ol BALPLIFE= 2.77E+Ol DAYS CBltOHIUH 51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----"--------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 3.17E-02 9.6SE-Ol 9.96E-Ol 

2.00E-Ol 6.0BE-02 9.26E-Ol 9.B7E-Ol 

3.00E-Ol 7.SlE-02 B.93E-Ol 9.6BE-Ol 

4.00E-Ol B.OBE-02 B.6lE-OI 9. 42E-Ol 

S.OOE-Ol 8. 22E-02 B.27E-OI 9.09E-Ol 

6.00E-Ol B.16E-02 7.B9E-Ol B.70E-Ol 

7.00E-Ol B.OOE-02 7. 48E-Ol B.2BE-Ol 

B.OOE-Ol 7.BIE-02 7.06E-OI 7.B4E-Ol 

9.00E-Ol 7.6lE-02 6. 63E-Ol 7.39E-Ol 

1.OOE+OO 7. 42E-02 6.20E-Ol 6. 94E-Ol 

2.00E+OO 6.I4E-02 2. 73E-Ol 3. 34E-Ol 

3.00E+OO S.46E-02 1.06E-Ol 1.60E-Ol 

4.00E+OO 4.9BE-02 3.9IE-02 B.B9E-02 

5.00E+OO 4.5BE-02 1. 42E-Q2 6.00E-02 

6.00E+OO 4. 23E-02 S.12E-03 4. 74E-02 

7.00E+OO 3. 92E-02 1. B4E-03 . 4.lOE-02 

B.OOE+OO 3.64E-02 6.6lE-04 3.7IE-02 

9.00E+OO 3.40E-02 2. 37E-04 3. 42E-02 

1.OOE+Ol 3.l7E-02 B.52E-05 3.lBE-02 

2.00E+Ol 1.B2E-02 O.OOE+OO 1. 82E-02 

3.00E+Ol 1.20E-02 O.OOE+OO 1.20E-02 

4.00E+Ol 8.44E-03 O.OOE+OO 8. 44E-03 

5.00E+0l 6.07E-03 O.OOE+OO 6.07E-03 

6.00E+OI 4.40E-03 O.OOE+OO 4.40E-03 

7.00E+Ol 3.20E-03 O.OOE+OO 3.20E-03 

8.00E+Ol 2. 33E-03 O.OOE+OO 2. 33E-03 

9.00E+Ol 1.70E-03 O.OOE+OO 1.70E-03 

1.OOE+02 1.25E-03 O.OOE+OO . 1.2SE-03 

2.00E+02 5.90E-OS O.OOE+OO 5.90E-05 

3.00E+02 3. 26E-06 O.OOE+OO 3. 26E-06 

4.00E+02 2.06E-07 O.OOE+OO 2.06E-07 

5.00E+02 1.43E-OB O.OOE+OO 1. 43E-OB 

B-507 
INGESTION f 1- 1.00B-01 IlALFLIP'E= 2.77E+01 DAYS CIIIlOHIUH 51 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 6.04E-04 6.00E-04 

2.00E-Ol 2. 69E-03 S.73E-03 

3.00E-01 S.S7E-03 1.8SE-02 

4.00E-01 8.6SE-03 3. 94E-02 

S.OOE-01 1. 16E-02 6. 72E-02 

6.00E-01 1. 44E-02 1.00E-01 

7.00E-01 1.70E-02 1. 37E-0l 

8.00E-01 1. 93E-02 1.77E-Ol 

9.00E-01 2.13E-02 2.17E-0l 

1.00E+OO· 2. 31E-02 2. 31E-02 2.S8E-Ol 2.SBE-01 

2.00E+OO 1. 12E-02 3. 37E-02 3.32E-Ol S.B4E-01 

3.00E+OO S.24E-03 3. 81E-02 1.60E-01 7. 29E-01 

4.00E+OO 3. 48E-OJ 4.07E-02 6.39E-02 7.7SE-01 

5.00E+OO 2.7BE-03 4. 24E-02 2. 39E-02 7. BOE-01 

6.00E+OO 2. 37E-03 4. 38E-02 8.72E-03 7. 69E-01 

7.00E+OO 2.06E-03 4.47E-02 3. 15E-03 7.S4E-01 

B.OOE+OO 1.80E-03 4.54E-02 1.13E-03 7. 36E-01 

9.00E+OO 1.SBE-03 4. 59E-02 4.08E-04 7.1BE-01 

1.00E+01 1. 39E-03 4. 61E-02 1.46E-04 7.01E-01 

2.00E+01 4. 13E-04 4. 24E-02 O.OOE+OO S.46E-01 

3.00E+01 1. 54E-04 3. S2E-02 O.OOE+OO 4.25E-0l 

4.00E+01 7.S7E-OS 2. 83E-02 O.OOE+OO 3.3IE-OI 

5.00E+01 4.S7E-OS 2.26E-02 O.OOE+OO 2. 58E-Ol 

6.00E+OI 3.07E-05 I. 79E-02 O.OOE+OO 2.0IE-Ol 

7.00E+Ol 2. 14E-05 1. 42E-02 O.OOE+OO 1.56E-01 

8.00E+01 1. 52E-OS 1.12E-02 O.OOE+OO 1.22E-Ol 

9.00E+01 1.09E-05 B.B2E-03 O.OOE+OO 9. 47E-02 

I.OOE+02 7.77E-06 6.95E-03 O.OOE+OO 7. 37E-02 

2.00E+02 2. 79E-07 6. 12E-04 O.OOE+OO 6.04E-03 

3.00E+02 1.05E-OB 5.17E-05 O.OOE+OO 4. 95E-04 

B-50B 
INGESTION f l= I.OOE-ol STABLE CHROMIUM 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 3.l8E-02 9.67E-Ol 9. 99E-Ol 

2.00E-Ol 6.llE-02 ~.JOE-Ol 9. 92E-Ol 

3.00E-Ol 7.S7E-02 9.00E-Ol 9. 76E-Ol 

4.00E-Ol 8.l6E-02 8.70E-Ol 9.S2E-Ol 

S.OOE-Ol 8. 33E-02 8.37E-0l 9.20E-Ol 

6.00E-Ol 8.28E-02 8.0lE-Ol 8.83E-Ol 

7.00E-Ol 8.l4E-02 7.62E-Ol 8.43E-Ol 

8.00E-Ol 7.97E-02 7.20E-Ol 8.00E-Ol 

9.00E-Ol 7.79E-02 6.78E-0l 7. 56E-Ol 

1.OOE+OO 7.6lE-02 6. 36E-Ol 7.l2E-Ol 

2.00E+OO 6.46E-02 2.87E-Ol 3.SlE-0l 

3.00E+OO 5. 89E-02 1.14E-Ol 1. 73E-Ol 

4.00E+OO S.5lE-02 4.32E-02 9. 82E-02 

5.00E+OO 5.l9E-02 1.6lE-02 6.80E-02 

6.00E+OO 4.92E-02 5.95E-03 S.5lE-02 

7.00E+OO 4.67E-02 2.19E-03 4.89E-02 

8.00E+OO 4.45E-02 8.08E-04 4.S3E-02 

9.00E+OO 4.25E-02 2. 97E-04 4. 28E-02 

1.OOE+Ol 4.08E-02 1.09E-04 4.09E-02 

2.00E+Ol 3.00E-02 O.OOE+OO 3.00E-02 

3.00E+Ol 2. 55E-02 O.OOE+OO 2. 55E-02 

4.00E+Ol 2.30E-02 O.OOE+OO 2.30E-02 

5.00E+Ol 2.12E-02 O.OOE+OO 2.12E-02 

6.00E+Ol 1.97E-02 O.OOE+OO 1.97E-02 

7.00E+Ol 1.84E-02 O.OOE+OO 1.84E-02 

8.00E+Ol 1.73E-02 O.OOE+OO 1. 73E-02 

9.00E+Ol 1. 62E-02 O.OOE+OO 1. 62E-02 

1.OOE+02 1.52E-02 O.OOE+OO 1. 52E-02 

2.00E+02 8. 78E-03 O.OOE+OO 8. 78E-03 

3.00E+02 5. 93E-03 O.OOE+OO 5. 93E-03 

4.00E+02 4. 57E-03 O.OOE+OO 4. 57E-03 

5.00E+02 3.87E-03 O.OOE+OO 3. 87E-03 

6.00E+02 3. 44E-03 O.OOE+OO 3. 44E-03 

7.00E+02 3.l4E-03 O.OOE+OO 3.14E-03 

8.00E+02 2.90E-03 O.OOE+OO 2.90E-03 

9.00E+02 2. 69E-03 O.OOE+OO 2. 69E-03 

"::,: '. 

1.OOE+03 2.5lE-03 O.OOE+OO 2.5lE-03 

2.00E+03 1.25E-03 O.OOE+OO 1. 25E-03 

3.00E+03 6.25E-04 O.OOE+OO 6. 25E-04 

4.00E+03 3.l3E-04 O.OOE+OO 3.13E-04 

5. QOE+03 1.56E-04 O.OOE+OO 1.56E-04 

6.00E+03 7.82E-05 O.OOE+OO 7. 82E-05 

7.00E+03 3.9lE-05 O.OOE+OO 3.9lE-05 

8.00E+03 1.96E-05 O.OOE+OO 1. 96E-05 

9.00E+03 9. 78E-06 O.OOE+OO 9. 78E-06 

1.OOE+04 4. 89E-06 O.OOE+OO 4. 89E-06 

B-509 
INGESTIOK f 1= 1.OOE-Q1 STABLE CHROMIUM 52 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ---------------------------~--------------------~----- SYSTEMIC NON-SYSTEMIC 

----------------~--------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6.06E-04 6.02E-04 

2.00E-Ol 2.71E-03 5. 76E-03 

3.00E-OI 5.6lE-03 1.87E-02 

4.00E-Ol 8. 73E-03 3. 98E-02 

5.00E-Ol 1.18E-02 6.80E-02 

6.00E-Ol 1. 47E-02 I.02E-O! 

7.00E-Ol 1. 73E-02 1.40E-Ol 

8.00E-OI 1. 96E-02 1.80E-Ol 

9.00E-Ol 2.l8E-02 2. 22E-Ol 

1.OOE+OO 2. 37E-02 2. 37E-02 2. 65E-Ol 2. 65E-Ol 

2.00E+OO 1. 17E-02 3.54E-02 3. 49E-Ol 6.13E-Ol 

3.00E+OO 5. 65E-03 4.1lE-02 1. 73E-Ol 7.86E-Ol· 

4.00E+OO 3. 85E-03 4.49E-02 7.06E-02 8. 57E-Ol 

5.00E+OO 3.l5E-03 4.8lE-02 2.7lE-02 8. 84E-Ol 

6.00E+OO 2. 75E-03 5.08E-02 1.0IE-02 8. 94E-Ol 

7.00E+OO 2. 45E-03 5. 33E-02 3. 76E-03 8.98E-Ol 

8.00E+OO 2.20E-03 5.55E-02 1.39E-03 8. 99E-Ol 

9.00E+OO 1. 98E-03 5. 75E-02 5.11E-04 9.00E-Ol 

, 1.00E+Ol 1.78E-03 5.92E-02 1.88E-04 9.00E-0l 

i· 2.00E+Ol 6.81E-04 7.00E-02 O.OOE+OO 9.00E.-Ol 

3.00E+Ol 3. 26E-04 7.45E-02 O.OOE+OO 9.00E-Ol 

4.00E+Ol 2.06E-04 7.70E-02 O.OOE+OO 9.00E-Ol 

5.00E+Ol 1.60E-04 7.88E-02 O.OOE+OO 9.00E-Ol 

6.00E+Ol 1. 38E-04 8.03E-02 O.OOE+OO 9.0QE-Ol 

7.00E+Ol I. 24E-04 8.l6E-02 O.OOE+OO 9.00E~OI 

8.00E+OI 1. 13E-04 8. 27E-02 O.OOE+OO 9.00E-OI 

9.00E+Ol 1.03E-04 8. 38E-02 O.OOE+OO 9.00E-0l 

1.OOE+02 9. 49E-05 8.48E-02 O.OOE+OO 9.00E-Ol 

2.00E+02 4.l6E-05 9. 12E-02 O.OOE+OO 9.00E-Ol 

3.00E+02 1.90E-05 9.4IE-02 O.OOE+OO 9.00E";'Ol 

4.00E+02 9.45E-06 9. 54E-02 O.OOE+OO 9.00E-OI 

5.00E+02 5. 32E-06 9.6IE-02 O.OOE+OO 9.00E-OI 

6.00E+02 3. 49E-b6 " 9. 66E-02 O.OOE+OO 9.00E-Ol 

7.00E+02 2. 64E-06 '. 9.69E-02 O.OOE+OO 9.00E-OI· 

8.00E+02 2.20E-06 9.71E-02 O.OOE+OO 9.00E;"OI 

9.00E+02 1. 95E-06 9. 73E-02 O.'()OE+OO 9.00E-OI 

1.OOE+03 1. 77E-06 9. 75E-02 O.OOE+OO 9.00E-Ol 

2.00E+03 8.67E-07 9.87E-02 O.OOE+OO 9.00E-OI 

3.00E+03 4. 34E-07 9. 94E-02 O.OOE+OO 9.00E-OI 

4.00E+03 2. I7E-07 9. 97E-02 O.OOE+OO 9.00E.,.Ol 

5.00E+03 I.08E-07 9. 98E-02 O.OOE+OO 9.00E-O!. 

6.00E+03 5. 42E-08 9. 99E-02 O.OOE+OO 9.00E-Ol 

7.00E+03 2.7IE-08 1.OOE-OI O.OOE+OO 9.00E;;"Ol 

8.00E+03 I. 36E-08 1.OOE-OI ,'O.OOE+OO 9.00E-Ol 

B-510 
INGESTION f 1- 1.00E-01 HALFLlFE= 3.13E+02 DAYS MANGARESE 54 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 3. 23E-02 9. 67E-OI 9. 99E-OI 

2.00E-OI 6. 34E-02 9.30E-OI 9. 93E-OI 

3.00E-OI 8.04E-02 8.99E-0l 9.80E-OI 

4.00E-OI 8. 89E-02 8.69E-OI 9. 58E-OI 

5.00E-OI' 9.30E-02 8. 36E-OI 9. 29E-OI 

6.00E-OI 9. 48E-02 8.00E-OI 8. 94E-OI 

7.00E-OI 9. 54E-02 7.60E-OI 8.56E-OI 

8.00E-OI 9. 54E-02 7.19E-OI 8.15E-OI 

9.00E-OI 9. 52E-02 6. 77E-OI 7.12E-OI 

1.00E+00 9. 47E-02 6. 34E-OI 7.29E-OI 

2.00E+00 8. 94E-02 2. 85E-0l 3.75E-0l 

3.00E+00 8. 46E-02 1.13E-Ol 1. 98E-OI 

4.00E+00 8.03E-02 4. 28E-02 1.23E-Ol 

5.00E+00 7. 66E-02 . I. 59E-02 9. 25E-02 

6.00E+00 7. 33E-02 5. 87E-03 7. 92E-02 

7.00E+00 7.04E-62 2.16E-03 7.25E-02 

8.00E+00 6. 77E-02 7.94E-04 6. 85E-02 

9.00E+00 6. 53E-02 2~92E-04 6. 56E-02 

1.00E+Ol 6.3IE-02 1.07E-04 6. 33E-02 

2.00E+OI 4. 84E-02 O.OOE+OO 4. 84E-02 

3.00E+OI 3. 92E-02 O.OOE+OO 3. 92E-02 

4.00E+Ol 3. 22E-02 O.OOE+OO 3. 22E-02 

5.00E+Ol 2. 64E-02 O.OOE+OO 2. 64E-02 

6.00E+Ol 2. 17E-02 O.OOE+OO 2.17E-02 

7.00E+OI 1.79E-02 O.OOE+OO 1.79E-02 

8.00E+Ol 1. 47E-02 O.OOE+OO I. 47E-02 

9.00E+OI 1.2IE-02 O.OOE+OO 1.2IE-02 

1.00E+02 9. 95E-03 O.OOE+OO 9. 95E-03 

2.00E+02 1.41E-03 O.OOE+OO 1.4IE-03 

3.00E+02 2.00E-04 O.OOE+OO 2.00E-04 

4.00E+02 2. 83E-05 O.OOE+OO 2. 83E-05 

5.00E+02 4.01E-06 O.OOE+OO 4.0IE-06 

6.00E+02 5. 68E-07 O.OOE+OO 5. 68E-07 

7.00E+02 8.04E-08 O.OOE+OO 8.04E-08 

8.00E+02 1.14E-08 O.OOE+OO 1. 14E-OB 

': I 

.... , 

, ' 

B-511 
INGESTION f l- 1.OOE-ol HALFLlFE- 3.13E+02 DAYS MANGANESE 54 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------_ ...... ---------------------- SYSTEMIC NON-SYSTEMIC 

-----------..... ------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 8.6IE-05 6.01E-04 

2.00E-OI 3. 99E-04 5. 75E-03 

3.00E-Ol 8.60E-04 1. 87E-02 

4.00E-OI I.40E-03 3. 97E-02 

5.00E-OI 1. 97E-03 6.79E-02 

6.00E-Ol 2. 55E-03 I.02E-OI 

7.00E-OI 3.14E-03 1.40E-OI 

8.00E-OI 3. 72E-03 I.80E-OI 

9.00E-OI 4.30E-03 2. 22E-OI 

I.OOE+OO 4. 87E-03 4. 87E-03 2. 64E-OI 2. 64E-OI 

2.00E+OO 5.3IE-03 I.02E-02 3.47E-OI 6.11E-OI 

3.00E+OO 4. 62E-03 1. 48E-02 1. 72E-OI 7.8IE-OI 

4.00E+OO 4.04E-03 I.88E-02 7.00E-02 8. 49E-OI 

5.00E+OO 3.S5E-03 2. 23E-02 2. 68E-02 8. 74E-OI 

6.00E+OO 3.14E-03 2. 54E-02 I.OOE-02 8. 82E-OI 

7.00E+OO 2. 79E-03 2.8IE-02 3.70E-03 8. 84E-OI 

8.00E+OO 2. 49E-03 3.05E-02 I.36E-03 8. 83E-OI 

9.00E+OO 2. 24E-03 3. 27E-02 5.0IE-04 B.82E-OI 

I.OOE+OI 2.03E-03 3.47E-02 I.84E-04 B.80E-OI 

2.00E+OI I.OIE-03 4.72E-02 O.OOE+OO B.6IE-OI 

3.00E+OI 7.13E-04 5.43E-02 O.OOE+OO 8.42E-OI 

4.00E+OI S.67E-04 5. 93E-02 O.OOE+OO 8. 24E-OI 

5.00E+OI 4. 63E-04 6.3IE-02 O.OOE+OO 8.06E-OI 

6.00E+OI 3.80E-04 6. 58E-02 O.OOE+OO 7. 88E-OI 

7.00E+OI 3.13E-04 6.77E-02 O.OOE+OO 7.7IE-0l 

B.OOE+OI 2. 57E-04 6.90E-02 O.OOE+OO 7.S4E-OI 

9.00E+OI 2.11E-04 6. 98E-02 O.OOE+OO 7. 37E-OI 

I.OOE+02 1. 74E-04 7.02E-02 O.OOE+OO 7.2IE-OI 

2.00E+02 2.46E-OS 6. 28E-02 O.OOE+OO . 5.78E-OI 

3.00E+02 3. 49E-06 5.12E-02 O.OOE+OO 4. 63E-OI 

4.00E+02 4. 94E-07 4.12E-02 O.OOE+OO 3.7IE-0l 

S.OOE+02 7.00E-08 3.30E-02 O.OOE+OO 2. 97E-OI 

B-SI2 
INGESTION fl'''' 1.OOE-ol STABLJil: IWfGANESE S5 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 3. 23E-02 9. 67E-Ol 9.99E-Ol 

2.00E-Ol 6. 34E-02 9.30E-Ol 9. 94E-Ol 

3.00E-Ol 8.04E-02 9.00E-ol 9.80E-Ol 

4.00E-Ol 8.90E-02 8.70E-Ol 9. 59E-Ol 

5.00E-Ol 9.31E-02 8.37E-Ol 9.30E-Ol 

6.00E-Ol 9. 49E-02 8.01E-Ol 8. 96E-Ol 

7.00E-Ol 9. 56E-02 7.62E-Ol 8.57E-Ol 

8.00E-Ol 9. 56E-02 7.20E-Ol 8. 16E-Ol 

9.00E-Ol 9. 53E-02 6. 78E-Ol 7.73E-Ol 

1.00E+00 9.49E-02 6. 36E-ol 7.31E-Ol 

2.00E+00 8. 98E-02 2.87E-Ol 3. 76E-Ol 

3.00E+00 8. 51E-02 1. 14E-Ol 1. 99E-ol 

4.00E+00 8. l1E-02 4. 32E-02 1. 24E-Ol 

5.00E+00 7. 75E-02 1.61E-02 9. 36E-02 

6.00E+00 7. 43E-02 5. 95E-03 8.02E-02 

7.00E+00 7. 15E-02 2. 19E-03 7. 36E-02 

8.00E+00 6. 89E-02 8.08E-04 6. 97E-02 

9.00E+00 6. 66E-02 2. 97E-04 6. 69E-02 

1.00E+Ol 6. 46E-02 1.09E-04 6. 47E-02 

2.00E+Ol 5.06E-02 O.OOE+OO 5.06E-02 

3.00E+Ol 4. 19E-02 O.OOE+OO 4. 19E-02 

4.00E+Ol 3. 52E-02 O.OOE+OO 3. 52E-02 

5.00E+Ol 2. 95E-02 O.OOE+OO 2. 95E-02 

6.00E+Ol 2. 48E-02 O.OOE+OO 2. 48E-02 

7.00E+Ol 2.09E-02 O.OOE+OO 2.09E-02 

8.00E+Ol 1. 76E-02 O.OOE+OO 1. 76E-02 

9.00E+Ol 1. 48E-02 O.OOE+OO 1.48E-02 

1.00E+02 1. 24E-02 O.OOE+OO 1. 24E-02 

2.00E+02 2.20E-03 O.OOE+OO 2.20E-03 

3.00E+02 3. 88E-04 O.OOE+OO 3. 88E-04 

4.00E+02 6. 87E-05 O.OOE+OO 6. 87E-05 

5.00E+02 1. 21E-05 O.OOE+OO 1.21E-05 

6.00E+02 2. 15E-06 O.OOE+OO 2. 15E-06 

7.00E+02 3.80E-07 O.OOE+OO 3.80E-07 

8.00E+02 6. 72E-08 O.OOE+OO 6. 72E-08 

9.00E+02 1. 19E-08 O.OOE+OO 1. 19E-08 ." 

B-513 
INGESTION fl"= I.OOE-ol STABLE MANGANESE 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 8. 62E-05 6.02E-04 

2.00B-Ol 3. 99E-04 5. 76E-03 

3.00E-OI 8.6IE-04 1.87E-02 

4.00E-Ol 1.40E-03 3. 98E-02 

5.00E-Ol 1.97E-03 6.80E-02 

6.00E-OI 2. 55E-03 I.02E-Ol 

7.00E-Ol 3.l4E-03 1.40E-Ol 

8.00E-Ol 3.13E-03 1.80E-Ol 

9.00E-Ol 4.3lE-03 2. 22E-OI 

1.OOE+OO 4. 88E-03 4. 88E-03 2. 65E-Ol 2.6SE-Ol 

2.00E+OO 5.33E-03 1.02E-02 3. 49E-Ol 6. 13E-OI 

3.00E+OO 4.6SE-03 1. 49E-02 1. 73E-OI 7. 86E-Ol 

4.00E+OO 4.08E-03 1. 89E-02 7.06E-02 8.57E-Ol 

5.00E+OO 3. 59E-03 2. 25E-02 2.71E-02 8. 84E-OI 

6.00E+OO 3.l8E-03 2. 57E-02 1.OlE-02 8. 94E-Ol 

7.00E+OO 2. 83E-03 2.8SE-02 3. 76E-03 8. 98E-Ol 

8.00E+OO 2. 54E-03 3.11E-02 1. 39E-03 8. 99E-Ol 

9.00E+OO 2. 29E-03 3. 34E-02 5.l1E-04 9.00E-Ol 

I.OOE+Ol 2.07E-03 3.S4E-02 1. 88E-04 9.00E-Ol 

2.00E+OI 1.05E-03 4. 94E-02 O.OOE+OO 9.00E-Ol 

3.00E+Ol 7. 63E-04 S.8IE-02 O.OOE+OO 9.00E-Ol 

4.00E+OI 6.20E-04 6. 48E-02 O.OOE+OO 9.00E-O! 

S.OOE+OI 5.17E-04 7.0SE-02 O.OOE+OO 9.00E-Ol 

6.00E+Ol 4. 34E-04 7.S2E-02 O.OOE+OO 9.00E-OI 

7.00E+Ol 3. 65E-04 7.9IE-02 O.OOE+OO 9.00E-OI 

8.00E+OI 3.07E-04 8.24E-02 O.OOE+OO 9.00E-Ol 

9.00E+Ol 2.S8E-04 8. 52E-02 O.OOE+OO 9.00E-Ol 

I.OOE+02 2.17E-04 8. 76E-02 O.OOE+OO 9.00E-Ol 

2.00E+02 3. 84E-OS 9. 78E-02 O.OOE+OO 9.00E-OI 

3.00E+02 6. 79E-06 9. 96E-02 O.OOE+OO 9.00E-OI 

4.00E+02 1.20E-06 9. 99E-02 O.OOE+OO 9.00E-OI 

S.OOE+02 2.12E-07 1.OOE-Ol O.OOE+OO 9.00E-OI 

6.00E+02 3.7SE-08 I.OOE-OI O.OOE+OO 9.00E-Ol 

'. 

B-S14 
INGESTION fl= 1.00£--01 IlALFLIFE= 9.86£+02 DAYS IRON 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 3. 24E-02 9. 67E-Ol 9. 99E-Ol 

2.00E-OI 6. 38E-02 9.30E-OI 9. 94E-Ol 

3.00E-Ol 8.13E-02 9.00E-Ol 9.8lE-Ol 

4.00E-Ol 9.03E-02 8.70E-Ol 9.60E-Ol 

S.OOE-Ol 9.S0E-02 8.37E-Ol 9. 32E-OI 

6.00E-Ol 9. 74E-02 8.00E-Ol 8. 98E-Ol 

7.00E-Ol 9. 86E-02 7.6lE-Ol 8.60E-Ol 

8.00E-Ol 9.93E-02 7.20E-Ol 8.l9E-Ol 

9.00E-Ol 9. 96E-02 6.78E-Ol 7.77E-Ol 

1.00E+00 9. 97E-02 6.3SE-Ol 7.3SE-Ol 

2.00E+00 9. 98E-02 2.86E-Ol 3. 86E-Ol 

3.00E+OO 9.97E-02 1.14E-Ol 2.13E-OI 

4.00E+00 9. 96E-02 4.30E-02 I.43E-OI 

S.OOE+OO 9.9SE-02 I.60E-02 I.I6E-OI 

6.00E+00 9. 94E-02 S.93E-03 I.OSE-Ol 

7.00E+00 9. 93E-02 2.l8E-03 1.OlE-Ol 

8.00E+00 9.92E-02 8.04E-04 1.OOE-OI 

9.00E+OO 9.9lE-02 2. 96E-04 9. 94E-02 

1.OOE+OI 9.90E-02 1.09E-04 9.9lE-02 

2.00E+OI 9.79E-02 O.OOE+OO 9. 79E-02 

3.00E+OI 9. 69E-02 O.OOE+OO 9. 69E-02 

4.00E+Ol 9. 59E-02 O.OOE+OO 9. 59E-02 

S.OOE+Ol 9. 49E-D2 O.OOE+OO 9. 49E-02 

6.00E+Ol 9. 39E-02 O.OOE+OO 9. 39E-02 

7.00E+Ol 9. 29E-02 O.OOE+OO 9. 29E-02 

8.00E+OI 9.20E-02 O.OOE+OO 9.20E-02 

9.00E+OI 9.10E-02 O.OOE+OO 9.l0E-02 

I.OOE+02 9.00E-02 O.OOE+OO 9.00E-02 

2.00E+02 8.11E-02 O.OOE+OO 8.11E-02 

3.00E+02 7.30E-02 O.OOE+OO 7.30E-02 . 4.00E+02 6. 57E-02 O.OOE+OO 6. S7E-02 

5.00E+02 S.92E-02 O.OOE+OO 5. 92E-02 

6.00E+02 S.33E-02 O.OOE+OO S.33E-02 

7.00E+02 4.80E-02 O.OOE+OO 4.80E-02 

8.00E+02 4. 32E-02 . O.OOE+OO 4. 32E-02 

9.00E+02 3. 89E-02 O.OOE+OO 3. 89E-02 -:. :', 1.00E+03 3. SOE-02 O.OOE+OO 3.50E-02 

2.00E+03 1. 23E-02 O.OOE+OO I. 23E-02 

3.00E+03 4.29E~03 O.OOE+OO 4. 29E-03 

4.00E+03 I.SOE-03 O.OOE+OO I.50E-03 

S.OOE+03 S.25E-04 O.OOE+OO '5. 25E-04 

6.00E+03 I. 84E-04 O.OOE+OO 1. 84E-04 

7.00E+03 6. 43E-OS 0.001';+00 6.43E-05 

8.00E+03 2. 25E-OS O.OOE+OO 2. 25E-05 

9.00E+03 7.88E-06 O.OOE+OO 7. 88E-06 

1.00E+04 2. 76E-06 O.OOE+OO 2. 76E-06 

B-SIS 
INGESTION f l- I.OOE-QI IlALFLIFE- 9.86B+02 DAYS IROB 55 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

------------------------- ---------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 4.68E-07 6.02E-04 

2.00E-Ol 2.l8E-06 5. 75E-03 

3.00E-Ol 4. 73E-06 1. 87E-02 

4.00E-Ol 7. 72E-06 3. 97E-02 

5.00E-Ol 1.09E-05 6.80E-02 

6.00E-Ol 1. 43E-05 1.02E-OI 

7.00E-Ol 1.77E-05 1.40E-Ol 

8.00E-Ol 2.llE-05 1.80E-Ol 

9.00E-Ol 2. 45E-05 2. 22E-Ol 

1.00E+OO 2.80E-05 2.80E-05 2. 64E-Ol 2. 64E-Ol 

2.00E+OO 3. 46E-05 6. 26E-05 3. 48E-Ol 6. 13E-Ol 

3.00E+OO 3. 45E-05 9.71E-05 1. 72E-Ol l.85E-Ol 

4.00E+OO 3. 45E-05 1. 32E-04 7.04E-02 8. 54E-Ol 

5.00E+OO 3.45E-OS· 1. 66E-04 2.70E-02 8.8lE-Q1 

6.00E+OO 3. 44E-05 2.00E-04 1.OlE-02 8.90E-Ol 

7.00E+OO 3. 44E-05 2. 34E-04 3. 74E-03 8. 93E-Ol 

8.00E+OO 3. 44E-05 2. 69E-04 1. 38E-03 8. 94E-Ol 

9.00E+OO 3. 43E-05 3.03E-04 5.07E-04 8. 94E-Ol 

1.OOE+Ol 3. 43E-05 3. 37E-04 1.87E-04 8. 94E-Ol 

2.00E+Ol 3.J9E-OS 6. 74E-04 O.OOE+OO 8. 87E-Ol 

3.00E+Ol 3. 36E-OS 1.OlE-03 O.OOE+OO 8.8lE-Ol 

4.00E+Ol 3. 32E-05 1. 33E-03 O.OOE+OO 8. 75E-Ol 

S.OOE+Ol 3. 29E-05 1. 65E-03 O.OOE+OO 8. 69E-Ol 

6.00E+Ol 3. 25E-OS 1. 97E-03 O.OOE+OO 8. 63E-Ol 

7.00E+Ol 3. 22E-05 2.28E-03 O.OOE+OO 8.S7E-Ol 

8.00E+Ol 3.l9E-05 2.5SE-03 O.OOE+OO 8.5lE-Ol 

9.00E+OI 3.15E-05 2.S8E-03 O.OOE+OO 8.45E-OI 

I.OOE+02 3.l2E-05 3. 17E-03 O.OOE+OO 8.J9E-Ol 

2.00E+02 2.8IE-05 5.8lE-OJ O.OOE+OO 7. 82E-OI 

3.00E+02 2. 53E-05 7. 99E-03 O.OOE+OO 7.29E-OI 

4.00E+02 2. 28E-05 9. 76E-OJ O.OOE+OO 6. 79E-Ol 

S.OOE+02 2.05E-05 1.12E-02 O.OOE+OO 6.33E-Ol 

6.00E+02 1. 85E-OS 1.2JE-02 O.OOE+OO S.90E-Ol 

7.00E+02 1. 66E-05 1.J2E-02 O.OOE+OO 5.50E-OI 

...... S.OOE+02 1.50E-05 1. 38E-02 O.OOE+OO 5.13E-OI 

9.00E+02 1. 35E-05 1. 42E-02 O.OOE+OO 4.7SE-Ol 

1.OOE+03 1.2lE-05 I.45E-02 O.OOE+OO 4.4SE-OI 

2.00E+OJ 4.2SE-06 1. 22E-02 O.OOE+OO 2.20E-OI 

3.00E+OJ 1.49E-06 7.S4E-03 O.OOE+OO I.09E-OI 

4.00E+03 5.20E-07 4.S0E-03 O.OOE+OO 5.40E-02 

5.00E+OJ I.S2E-07 2. 44E-OJ O.OOE+OO 2. 67E-02 

6.00E+OJ 6.J7E-08 1. 29E-03 O.OOE+OO 1.J2E-02 

7.00E+OJ 2. 23E-OS 6. 63E-04 O.OOE+OO 6.5SE-03 

B-5I6 
INGESTION f l- 1.OOE-ol STABLE IRON 56 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 3. 24E-02 9.67E-Ol 9. 99E-Ol 

2.00E-Ol 6. 38E-Q2 9.30E-Ol 9~94E-Ol 

3.00E-0l 8.l3E-02 9.00E-0l 9.8lE-Ol 

4.00E-Ol 9.04E-02 8.70E-Ol 9.60E-Ol 

5.00E-Ol 9.50E-02 8. 37E-Ol 9. 32E-Ol 

6.00E-Ol 9. 74E-02 8.0lE-Ol 8. 98E-Ol 

7.00E-Ol 9. 87E-02 7.62E-0l 8.60E-Ol 

8.00E-Ol 9. 93E-02 7.20E-Ol 8.20E-Ol 

9.00E-Ol 9.96E-02 6. 78E-Ol 7.78E-Ol 

1.OOE+OO 9. 98E-02 6. 36E-Ol 7. 35E-Ol 

2.00E+OO 9. 99E-02 2. 87E-Ol 3. 86E-Ol 

3.00E+OO 9.99E-02 1.14E-Ol 2.l4E-Ol 

4.00E+OO 9.99E-02 4.32E-02 1.43E-Ol 

5.00E+OO 9. 98E-02 1.6lE-02 1. 1 6E-O 1 

6.00E+OO 9.98E-02 S.95E-03 I.06E-Ol 

7.00E+OO 9. 98E-02 2.l9E-03 1.02E-Ol 

8.00E+OO 9.97E-02 8.08E-04 1.OlE-Ol 

9.00E+OO 9.97E-02 2.97E-04 I.OOE-Ol 

1.OOE+Ol 9.97E-02 1.09E-04 9. 98E-02 

2.00E+Ol 9. 93E-02 O.OOE+OO 9. 93E-02 

3.00E+Ol 9.90E-02 O.OOE+OO 9.90E-02 

4.00E+Ol 9. 86E-02 O.OOE+OO 9.86E-02 

5.00E+Ol 9. 83E-02 O.OOE+OO 9. 83E-02 

6.00E+Ol 9. 79E-02 O.OOE+OO 9. 79E-02 

7.00E+Ol 9. 76E-02 O.OOE+OO 9. 76E-02 

8.00E+Ol 9. 73E-02 O.OOE+OO 9. 73E-02 

9.00E+Ol 9.69E-02 O.OOE+OO 9. 69E-02 

1.OOE+02 9. 66E-02 O.OOE+OO 9. 66E-02 

2.00E+02 9. 33E-02 O.OOE+OO 9. 33E-02 

3.00E+02 9.0lE-02 O.OOE+OO 9.0lE-02 

4.00E+02 8.71E-02 O.OOE+OO 8.71E-02 

S.OOE+02 '8.4lE-02 O.OOE+OO 8.4lE-02 

6.00E+02 8.l2E-02 O.OOE+OO 8.l2E-02 

7.00E+02 7.8SE-Q2 O.OOE+OO 7.8SE-02 

8.00E+02 7.58E-02 O.OOE+OO 7.S8E-02 

-.# ' 9.00E+02 7.32E-02 O.OOE+OO 7. 32E-02 

1.OOE+03 7.07E-02 O.OOE+OO 7.07E-02 

2.00E+03 S.OOE-02 O.OOE+OO 5.00E-02 

3.00E+03 3. 54E-02 O.OOE+OO 3.S4E-02 

4.00E+03 2.S0E-02 O.OOE+OO 2.50E-02 

5.00E+03 1.77E-02 O.OOE+OO 1. 77E-02 

7.00E+03 8. 84E-03 O.OOE+OO 8.ME-03 

8.00E+03 6.2SE-03 O.OOE+OO 6. 25E-03 

9.00E+03 4. 42E-03 O.OOE+OO 4. 42E-03 

1.OOE+04 3.13E-03 O.OOE+OO 3.l3E-03 

2.00E+04 9. 78E-OS O.OOE+OO 9.78E-05 

B-517 
INGESTION f 1- 1.00£-61 STABLE IROII 56 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4.6SE-07 6.02E-04 

2.00E-Ol 2.lSE-06 5.76E-03 

3.00E-Ol 4. 73E-06 1.B7E-02 

4.00E-Ol 7. 72E-06 3.9BE-02 

5.00E-Ol 1.09E-05 6. BOE-02 

6.00E-Ol 1. 43E-05 1.02E-Ol 

7.00E-Ol 1.77E-05 1.40E-Ol 

B.OOE-Ol 2.llE-05 1. BOE-Ol 

9.00E-Ol 2. 46E-05 2.22E-Ol 

1.OOE+OO 2.80E-Q5 2.80E-05 2. 65E-Ol 2. 65E-Ol 

2.00E+OO 3. 46E-05 6. 26E-05 3. 49E-Ol 6.13E-Ol 

3.00E+OO 3. 46E-Q5 9. 73E-Q5 1. 73E-Ol 7. 86E-Ol 

4 .. 00E+OO 3. 46E-05 1.32E-04 7.06E-02 8.57E-0l 

5.00E+OO 3. 46E-05 1.66E-Q4 2.71E-02 8.B4E-Ol 

6.00E+OO 3. 46E-05 2.01E-04 1.OlE-02 B.94E...;.Ol 

7.00E+OO 3. 46E-05 2. 36E-04 3. 76E-03 8.9BE-Ol 

B.OOE+OO 3. 46E-05 2.70E-04 1.39E-03 8. 99E-Ol 

9.00E+OO 3. 46E-05 3.05E-04 5.llE-04 9.00E-Ol 

1.OOE+Ol 3. 45E-05 3. 39E-04 1.8BE-04 9.00E-Ol 

2.00E+Ol 3. 44E-05 6.B4E-04 O.OOE+OO 9.00E-Ol 

3.00E+0l 3. 43E-05 1.03E-03 O.OOE+OO 9.00E-Ol 

4.00E+Ol 3. 42E-05 1. 37E-03 O.OOE+OO 9.00E-Ol 

5.00E+Ol 3. 41E-05 1.7lE-03 O.OOE+OO 9.00E-Ol 

7.00E+Ol 3. 38E-05 2. 39E-03 O.OOE+OO 9.0QE-Ol 

8.00E+Ol 3. 37E-05 2. 73E-03 O.OOE+OO 9.00E-0l 

9.00E+Ol 3. 36E-05 3.06E-03 O.OOE+OO 9.00E-Ol 

1.00E+02 3. 35E-05 3.40E-03 O.OOE+OO 9.00E-Ol 

2.00E+02 . 3.23E-05 6. 69E-03 O.OOE+OO 9.00E-Ol 

3.00E+02 3. 12E-05 9.B7E-03 O.OOE+OO 9.00E-Ol 

4.00E+02 3.02E-05 1. 29E-02 O.OOE+OO 9.00E-Ol 

5.00E+02 2.9lE-05 1.59E-02 O.OOE+OO 9.00E-Ol 

7.00E+02 2. 72E-05 2.l5E-02 O.OOE+OO 9.00E-Ol 

8.00E+02 2. 63E-05 2. 42E-02 O.OOE+OO 9.00E-Ol 

9.00E+02 2. 54E-05 2. 68E-02 O.OOE+OO 9.00E-Ol 

1.00E+03 2. 45E-05 2. 93E-02 O.OOE+OO 9.00E-Ol 

2.00E+03 1.73E-05 5.00E-02 O.OOE+OO 9.00E-Ol 

3.00E+03 1. 23E-05 6. 46E-02 O.OOE+OO 9.00E-0l 

4.00E+03 8. 67E-06 . 7.50E-02 O.OOE+OO 9.00E-Ol 

5.00E+03 6.l3E-06 B.23E-Q2 O.OOE+OO 9.00E-Ol 

7.00E+03 3.06E-06 9.l2E-02 O.OOE+OO 9.00E-Ol 

8.00E+03 2.l7E-06 9. 37E-02 O.OOE+OO 9.00E-Ol 

9.00E+03 1. 53E-06 9. 56E-02 O.OOE+OO 9.00E-Ol 

1.OOE+04 1.OBE-06 9. 69E-02 O.OOE+OO 9.00E-0l 

2.00E+04 3. 39E-08 9. 99E-02 O.OOE+OO 9.00E...;.Ol 

B-518 
INGESTION fl= 1.00£-01 BALFLlFE= 4.45£+01 DAYS IRON 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----~--------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 3. 23E-02 9. 65E-Ol 9. 98E-OI 

2.00E-Ol 6. 36E-02 9.28E-Ol 9.91E-Ol 

3.00E-Ol 8.09E-02 8. 96E-Ol 9.77E-OI 

4.00E-Ol 8. 98E-02 8.64E-Ol 9.54E-Ol 

S.OOE-Ol 9.43E-02 8.30E-Ol 9.25E-OI 

6.00E-OI 9. 65E-02 7.93E-Ol 8.90E-Ol 

7.00E-0l 9. 76E-02 7.S3E-Ol 8.S1E-Ol 

8.00E-Ol 9.8lE-02 7.llE-Ol 8o10E-Ol 

9.00E-Ol 9. 82E-02 6.69E-Ol 7.67E-Ol 

1.OOE+OO 9. 83E-02 6. 26E-Ol 7. 24E-Ol 

2.00E+OO 9. 69E-02 2. 78E-Ol 3. 75E-Ol 

3.00E+OO 9. 53E-02 1.09E-Ol 2.04E-Ol 

4.00E+OO 9.38E-02 4.06E-02 I. 34E-Ol 

S.OOE+OO 9. 24E-02 1.49E-02 I.07E-OI 

6.00E+OO 9.09E-02 5. 42E-03 9.63E-02 

7.00E+OO 8.9SE-02 I. 97E-03 9.14E-02 

8.00E+OO 8.81E-02 7.13E-04 8. 88E-02 

9.00E+OO 8. 67E-02 2.S9E-04 8. 69E-02 

1.OOE+OI 8.S3E-02 9. 37E-05 8.54E-02 

2.00E+Ol 7.27E-02 O.OOE+OO 7.27E-02 

3.00E+Ol 6.20E-02 O.OOE+OO 6.20E-02 

4.00E+OI S.29E-02 O.OOE+OO 5. 29E-02 

S.OOE+Ol 4.S1E-02 O.OOE+OO 4.51E-02 

6.00E+OI 3. 85E-02 O.OOE+OO 3. 85E-02 

7.00E+Ol 3. 28E-02 O.OOE+OO 3. 28E-02 

8.00E+OI 2.80E-02 O.OOE+OO 2.80E-02 

9.00E+Ol 2. 39E-02 O.OOE+OO 2. 39E-02 

1.OOE+02 2.04E-02 O.OOE+OO 2.04E-02 

2.00E+02 4.15E-03 O.OOE+OO 4.15E-03 

3.00E+02 8.45E-04 O.OOE+OO 8. 45E-04 

4.00E+02 1.72E-04 O.OOE+OO 1. 72E-04 

5.00E+02 3.51E-OS O.OOE+OO 3.51E-05 

6.00E+02 7.14E-06 O.OOE+OO 7.14E-06 

7.00E+02 1.45E-06 O.OOE+OO 1. 45E-06 

8.00E+02 2. 96E-07 O.OOE+OO 2. 96E-07 

9.00E+02 6.03E-08 O.OOE+OO 6.03E-08 

1.OOE+03 1. 23E-08 O.OOE+OO I. 23E-08 

B-519 
INGESTION fl= 1.00B-ol HALFLIFE= 4.4SB+Ol DAYS IK.oN 59 

TIME AFTER FRACTION .oF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON~SYSTEMIC 

------------------------- ----------------------- 24-H.oUR ACCUMULATED 24-H.oUR ACCmWLATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE~Ol 4. 67E-07 6.0lE-04 

2.00E-Ol 2.l7E-06 s.74E-03 

3.00E-Ol 4.7IE-06 1.S6E-02 

4.00E-Ol 7.67E-06 3.9sE-02 

s.OOE-DI I.D9E-Ds 6.7sE-D2 

6.00E-Dl I.4lE-DS 1. DlE-Dl 

7. DOE-Ol I.7sE-DS 1.3BE-Ol 

B.OOE-OI 2.0SE-Os I.7BE-DI 9.0DE~Ol 2. 42E-Ds 2.l9E-Ol 

1.ODE+OO 2.76E~DS 2. 76E-D5 2.6IE-Ol 2.6IE-DI 

2.00E+OO 3. 36E-OS 6.D7E-Ds 3.3SE-Ol S.9SE-Dl 

3.00E+DO 3.30E-05 9.2SE-Ds 1.6SE-Ol 7.sDE-Dl 

4.00E+OO 3.2SE-OS I. 24E-D4 6.63E-02 B.DsE-OI 

s.ODE+OO 3.20E-OS 1. 54E-04 2.s0E-02 8.lBE-OI 

6.0DE+OO 3.lSE-OS I.S3E-D4 9.23E-03 S.14E-Dl 

7.00E+DO 3.lDE-DS 2.11E-D4 3. 37E-D3 B.DSE-OI 

B.OOE+OO 3.0SE-05 2. 39E-D4 I.22E-03 7. 94E-Ol 

9.0DE+OO 3.00E-OS 2.65E~04 4. 44E-D4 7.B2E-Ol 

1.ODE+OI 2. 96E-OS 2.90E-D4 1.6lE-04 7.70E-Ol 

2.00E+Ol 2.S2E-Ds S.OlE-D4 O.OOE+OO 6.59E~Ol 

3.00E+Ol 2.lSE-OS 6. 44E-D4 O.DOE+OO S.64E-OI 

4.00E+Ol 1. 83E-Os 7.3SE-D4 O.OOE+OO 4.S3E-Ol 

s.DDE+DI I.S6E-DS 7. 86E-04 D. DDE+OD 4.13E-Ol 

6 • .oDE +.0 1 1. 33E-OS 8.D6E-D4 O.ODE+DD 3.S4E-OI 

7.DDE+Dl 1. 14E-Ds B.D4E-D4 D.DDE+OO 3.03E-Ol 

B.DDE+Dl 9.7.oF.-06 7. BsE-D4 D.DDE+DD 2.s9E-Dl 

9.DDE+Dl 8.2BE-D6 7.s5E-D4 D.DDE+OO 2. 22E-Dl 

1. DOE+D2 7.D6E-D6 7. 17E-D4 D.DDE+DD 1.9DE-Dl 

2.DDE+D2 1. 44E-D6 2. 97E-D4 D.DDE+OO 4.DDE-D2 

3.DDE+D2 2. 93E-D7 9.2SE-Ds O.DDE+DD B.44E-D3 

4. DDE+D2 s.96E-D8 2. 56E-DS D.DDE+OO 1.7BE-D3 

s.DDE+D2 1.2lE-DS 6. 63E-D6 D.DDE+DD 3. 75E-D4 

B-s2D 
DJGESTION fl== 5.008-02 BA.LFLIP'E== 7. 08E+Ol DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 51E-02 9.83E-01 9. 98E-01 

2.00E-01 2. 89E-02 9.61E-Ol 9.90E-Ol 

3.00E-Ol 3. 55E-02 9. 38E-01 9. 74E-01 

4.00E-Ol 3. 78E-02 9.l1E-01 9.49E-01 

5.00E-Ol 3.80E-02 . 8.79E-01 9. 17E-01 

6.00E-01 3.71E-02 8.41E-01 8. 79E-Ol 

7.00E-01 3. 58E-02 8.01E-01 8. 36E-01 

8.00E-01 3. 44E-02 7.57E-Ol 7. 92E-01 

9.00E-01 3.30E-02 7.13E-Ol 7.46E-01 

1.00E+00 3.17E-02 6. 68E-01 6.99E-01 

2.00E+00 2. 37E-02 2. 99E-01 3. 23E-01 

3.00E+00 2.06E-02 1.18E-01 1. 38E-01 

4.00E+00 1. 88E-02 4. 42E-02 6.31E-02 

5.00E+00 1. 75E-02 1. 63E-02 3. 38E-02 

6.00E+00 1. 63E-02 5. 98E-03 2. 23E-02 

7.00E+00 1. 53E-02 2. 18E-03 1. 75E-02 

8.00E+00 1. 45E-02 7.96E-04 1. 52E-02 

9.00E+00 1. 37E-02 2.90E-04 1. 39E-02 

1.00E+Ol 1. 29E-02 1.06E-04 1.30E-02 

2.00E+OI 8. 56E-03 O.OOE+OO 8. 56E-03 

3.00E+Ol 6. 63E-03 O.OOE+OO 6. 63E-03 

4.00E+OI 5.50E-03 O.OOE+OO 5.50E...,03 

5.00E+OI 4. 69E-03 O.OOE+OO 4.69E-03 

6.00E+OI 4.04E-03 O.OOE+OO 4.04E-03 

7.00E+OI 3.50E-03 O.OOE+OO 3.50E-03 

8.00E+OI 3.04E-03 O.OOE+OO 3.04E-03 

9.00E+OI 2. 65E-03 O.OOE+OO 2. 65E-03 

1.00E+02 2. 32E-03 O.OOE+OO 2. 32E-03 

2.00E+02 6. 64E-04 O.OOE+OO 6. 64E-04 

3.00E+02 2.13E-04 O.OOE+OO 2.13E-04 

4.00E+02 7.14E-05 O.OOE+OO 7.14E-05 

5.00E+02 2. 44E-05 O.OOE+OO 2. 44E-05 

6.00E+02 8. 37E-06 O.OOE+OO 8. 37E-06 

7.00E+02 2. 88E-06 O.OOE+OO 2. 88E-06 

8.00E+02 9. 92E-07 O.OOE+OO 9. 92E-07 

9.00E+02 3.42E-07 O.OOE+OO 3. 42E-07 

,.',.' 1.00E+03 1.18E-07 O.OOE+OO 1.18E-07 

B-521 
INGESTION f1= 5.00E-02 BALFLIFE- 7. 08E+O 1 DAYS COBALT 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE -------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

I.OOE-OI 3.17E-04 7.4IE-04 

2.00E-OI 1.42E-03 6.43E-03 

3.00E-OI 2.96E-03 2.02E-02 

4.00E-OI 4. 62E-03 4.2SE-02 

, S.OOE-OI 6. 23E-03 7.23E-02 

6.00E-OI 7.74E-03 I.08E-OI 

7.00E-OI 9. llE-03 1.48E-OI 

8.00E-OI I.03E-02 1.90E-Ol 

9.00E-Ol 1.14E-02 2. 34E-OI 

I.OOE+OO 1. 24E-02 1.24E-02 2.7BE-OI 2. 78E-OI 

2.00E+OO S.43E-03 l.77E-02 3. 64E-OI 6.40E-OI 

3.00E+OO 2.03E-03 1. 96E-02 1. 79E-Ol 8.13E-OI 

4.00E+OO 1.IIE-03 2.0SE-02 7. 28E-02 8. 78E-OI 

S.OOE+OO 8.09E-04 2.IIE-02 2.7BE-02 8.97E-OI 

6.00E+OO 6. 76E-04 2.16E-02 I.OSE-02 B.99E-OI 

7.00E+OO 5.B9E-04 2.19E-02 ·3.99E-03 8. 94E:':'OI 

8.00E+OO 5.2IE-04 2.22E-02 1.59E-03 B.B7E-OI 

9.00E+OO 4. 63E-04 2.2SE-02 6.97E-04 8. 79E-OI 

I.OOE+OI 4.12E-04 2. 27E-02 3.SBE-04 8.7IE-OI 

2.00E+OI I. 36E-04 2. 28E-02 S.85E-OS 7.9IE-OI 

3.00E+OI S.44E-OS 2.14E-02 2.33E-OS 7.17E-OI 

4.00E+OI 2.8IE-OS 1.98E-02 1.20E-OS 6.SIE-OI 

S.OOE+OI 1. 83E-OS 1. B2E-02 7. B4E-06 S.90B-OI 

6.00E+OI 1.36E-OS 1.66E-02 S.B5E-06 5.3SE-OI 

7.00E+OI I.08E-05 I.S2E-02 4.63E-06 4.8SE-OI 

B.OOE+OI B.74E-06 1. 39E-02 3.7SE-06 4.40E-OI. 

9.00E+OI 7.15E-06 1.26E-02 3.06E-06 3. 99E-OI 

I.OOE+02 5.B7E-06 I.15E-02 2.S2E-06 3. 62E-OI 

2.00E+02 9.3IE-07 4. 48E-03 3.99E-07 1.36E-OI 

3.00E+02 1.92E-07 1.7IE-03 8.2IE-08 5. llE-02 

4.00E+02 S.07E-OB 6.47E-04 2.17E-OB 1.92E-02 

S.OOE+02 I.S7E-OB 2.45E-04 O.OOE+OO 7.2IE-03 

B-522 
INGESTION f 1 = 5.00E-02 STABLE COBALT 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 51E-02 9. 84E-Ol 9. 99E-Ol 

2.00E-Ol 2. 89E-02 9. 63E-Ol 9.92E-Ol 

3.00E-Ol 3. 56E-02 9.41E-Ol 9. 77E-Ol 

4.00E-Ol 3.80E-02 9. 15E-Ol 9.53E-Ol 

5.00E-Ol 3. 82E-02 8.83E-Ol 9.21E-Ol 

6.00E-Ol 3. 73E-02 8.46E-Ol 8. 84E-Ol 

7.00E-Ol 3. 61E-02 8.06E-Ol 8. 42E-Ol 

8.00E-Ol 3.47E-02 7.63E-Ol 7.98E-Ol 

9.00E-Ol 3. 33E-02 7.19E-Ol 7. 52E-Ol 

1.00E+00 3.20E-02 6. 74E-Ol 7.06E-Ol 

2.00E+00 2. 42E-02 3.05E-Ol 3. 29E-Ol 

3.00E+00 2. 12E-02 1.21E-Ol 1.42E-Ol 

4.00E+00 1.96E-02 4.60E-02 6. 56E-02 

5.00E+00 1. 84E-02 1.71E-02 3. 55E-02 

6.00E+00 1. 73E-02 6. 34E-03 2. 37E-02 

7.00E+00 1. 64E-02 2. 34E-03 1. 88E-02 

8.00E+00 1. 56E-02 8. 61E-04 1.65E-02 

9.00E+00 1.49E-02 3.17E-04 1. 52E-02 

1.00E+Ol 1.43E-02 1. 17E-04 1. 44E-02 

2.00E+Ol 1.04E-02 O.OOE+OO 1.04E-02 

3.00E+Ol 8.90E-03 O.OOE+OO 8.90E-03 

4.00E+Ol 8. 14E-03 O.OOE+OO 8. 14E-03 

5.00E+Ol 7. 65E-03 O.OOE+OO 7. 65E-03 

6.00E+Ol 7.27E-03 O.OOE+OO 7. 27E-03 

7.00E+Ol 6. 94E-03 O.OOE+OO 6. 94E-03 

8.00E+Ol 6. 66E-03 O.OOE+OO 6. 66E-03 

9.00E+Ol 6.40E-03 O.OOE+OO 6.40E-03 

1.00E+02 6. 16E-03 O.OOE+OO 6. 16E-03 

2.00E+02 4.70E-03 O.OOE+OO 4.70E-03 

3.00E+02 4.01E-03 O.OOE+OO 4.01E-03 

4.00E+02 3. 59E-03 O.OOE+OO 3.59E-03 

5.00E+02 3. 26E-03 O.OOE+OO 3. 26E-03 

6.00E+02 2. 98E-03 O.OOE+OO 2. 98E-03 

7.00E+02 2. 73E-03 O.OOE+OO 2. 73E-03 

8.00E+02 2.50E-03 O.OOE+OO 2.50E-03 

9.00E+02 2. 29E-03 O.OOE+OO 2. 29E-03 .. 1.00E+03 2.IOE-03 O.OOE+OO 2.IOE-03 

2.00E+03 8. 84E-04 O.OOE+OO 8. 84E-04 

3.00E+03 3.72E-04 O.OOE+OO 3. 72E-04 

4.00E+03 1. 56E-04 O.OOE+OO 1. 56E-04 

5.00E+03 6. 58E-05 O.OOE+OO 6. 58E-05 

6.00E+03 2. 76E-05 O.OOE+OO 2. 76E-05 

7.00E+03 1. 16E-05 O.OOE+OO 1.16E-05 

8.00E+03 4. 89E-06 O.OOE+OO 4. 89E-06 

9.00E+03 2.06E-06 O.OOE+OO 2.06E-06 

1.00E+04 8. 64E-07 O.OOE+OO 8. 64E-07 

B-523 
INGESTION f l - 5.00E-02 STABLE COBALT 59 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.17E-04 7. 42E-04 

2.00E-Ol 1. 43E-03 6.44E-03 

3.00E-Ol 2. 97E-03 2.03E-02 

4.00E-Ol 4. 63E-03 4. 27E-02 

S.OOE-Ol 6. 27E-03 7. 26E-02 

6.00E-Ol 7. 79E-03 1.0SE-ol 

7.00E-Ol 9. 17E-03 1. 49E-Ol 

S.OOE-Ol 1.04E-02 1.92E-Ol 

9.00E-Ol 1.lSE-02 2.'36E-Ol 

1.OOE+OO 1.2SE-02 1.2SE-02 2.S1E-Ol 2.S1E-Ol 

2.00E+OO S.S4E-03 1.81E-02 3. nE-Ol 6. S3E-Ol 

3.00E+OO 2.09E-03 2.01E-02 1.8SE-Ol S.37E-Ol 

4.00E+OO 1.lSE-03 2.13E-02 7.S7E-02 9.13E-Ol 

S.OOE+OO 8.S0E-04 2.21E-02 2. 92E-02 9.42E-Ol 

6.00E+OO 7.17E-04 2. 29E-02 1. 11E-02 9.S3E-Ol 

7.00E+OO 6.31E-04 2.3SE-02 4. 27E-03 9.S8E-Ol 

8.00E+OO S.64E-04 2. 41E-02 1.12E-03 9.S9E-Ol 

9.00E+OO S.OSE-04 2. 46E-02 7. 61E-04 9.60E-Ol 

1.OOE+Ol 4.S4E-04 2.S0E-02 3.9SE-04 9.61E-Ol 

2.00E+Ol 1. 66E-04 2.77E-02 7.11E-OS 9. 62E-Ol 

3.00E+Ol 7. 29E-OS 2.8SE-02 3.l3E-OS 9. 62E-Ol 

4.00E+Ol 4. 16E-OS 2. 93E-02 1.7SE-OS 9. 63E-Ol 

S.OOE+Ol 2. 99E-OS 2. 96E-02 1.2SE-OS 9. 63E-Ol 

6.00E+Ol 2.4SE-OS 2. 99E-02 1.OSE-oS 9. 63E-Ol 

7.00E+Ol 2. 14E-OS 3.01E-02 9.1SE-06 9. 63E-Ol 

S.OOE+Ol 1.91E-OS 3.03E-02 S.20E-06 9. 63E-Ol 

9.00E+Ol 1.13E-OS 3.0SE-02 7.40E-06 9. 63E-Ol 

1.OOE+02 I.S6E-OS 3.07E-02 '6.70E-06 9. 63E-Ol 

2.00E+02 6.60E-06 3.17E-02 2.S3E-06 9. 64E-Ol 

3.00E+02 3. 61E-06 3. 22E-02 1.SSE-06 9. 64E-ol 

4.00E+02 2.SSE-06 3.2SE-02 1.09E-06 9. 64E-Ol 

S.OOE+02 2.09E-06 3. 27E-02 S.97E-07 9. 64E-Ol 

6.00E+02 I.S4E-06 3. 29E-02 7.90E-07 9. 64E-Ol 

7.00E+02 1.67E-06 3.31E-02 7.14E-07 9. 64E-Ol 

S.OOE+02 1.S2E-06 3. 32E-02 6. S2E-07 9. 64E-Ol 

9.00E+02 1.39E-06 3. 34E-02 S.97E-07 9. 64E-Ol - . - ~ 1.OOE+03 1.2SE-06 3.3SE-02 S.47E-07 9. 64E-Ol 

2.00E+03 5. 36E-07 3. 44E-02 2.30E-07 9.6SE-Ol 

3.00E+03 2. 26E-07 3. 47E-02 9. 67E-08 9.6SE-Ol 

4.00E+03 9. 49E-OS 3. 49E-02 4.07E-08 9.6SE-Ol 

S.OOE+03 3. 99E-OS 3. SOE-02 1.11E-08 9.6SE-Ol 

6.00E+03 1. 68E-OS 3.S0E-02 O.OOE+OO 9.6SE-Ol 

B-S24 
INGESTION fl= 5.00£-02 BALFLIFE= 1.92£+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 51E-02 9. 84E-Ol 9.99E-Ol 

2.00E-01 2. 89E-02 9.63E-01 9. 92E-01 

3.00E-01 3. 56E-02 9.41E-01 9.77E-01 

4.00E-01 3. 79E-02 9. 15E-01 9. 53E-01 

5.00E-01 3.82E-'02 8. 83E-01 9.21E-01 

6.00E-Ol 3. 73E-02 8.46E-01 8. 84E-01 

7.00E-01 3. 61E-02 8.06E-01 8.42E-01 

8.00E-01 3.47E-02 7. 63E-Ol 7. 98E-Ol 

9.00E-01 3. 33E-02 7.19E-01 7.52E-01 

1.00E+00 3.20E-02 6. 74E-01 7.06E-01 

2.00E+00 2. 42E-02 3.05E-Ol 3. 29E-Ol 

3.00E+00 2. 12E-02 1.21E-01 1.42E-01 

4.00E+00 1. 95E-02 4. 59E-02 6. 55E-02 

5.00E+00 1. 83E-02 l.71E-02 3. 54E-02 

6.00E+00 1.73E-02 6.·33E-03 2. 36E-02 

7.00E+00 1. 64E-02 2. 33E-03 l.87E-02 

8.00E+00 1. 56E-02 8.59E-04 1. 64E-02 

9.00E+00 l.49E-02 3. 16E-04 1. 52E-02 

1.00E+01 1. 42E-02 1. 16E-04 1. 43E-02 

2.00E+01 1.03E-02 O.OOE+OO 1.03E-02 

3.00E+01 8.80E-03 O.OOE+OO 8.80E-03 

4.00E+01 8.02E-03 O.OOE+OO 8.02E-03 

5.00E+01 7.51E-03 O.OOE+OO 7.51E-03 

6.00E+01 7.11E-03 O.OOE+OO 7.llE-03 

7.00E+01 6.77E-03 O.OOE+OO 6.77E-03 

8.00E+01 6.47E-03 O.OOE+OO 6.47E-03 

9.00E+01 6. 19E-03 O.OOE+OO 6. 19E-03 

l.00E+02 5. 95E-03 O.OOE+OO 5. 95E-03 

2.00E+02 4. 38E-03 O.OOE+OO 4. 38E-03 

3.00E+02 3.60E-03 O.OOE+OO 3.60E-03 

4.00£+02 3.1OE-03 O.OOE+OO 3.1OE-03 

5.00E+02 2.72E-03 O.OOE+OO 2. 72E-03 

6.00E+02 2.40E-03 O.OOE+OO 2.40E-03 

7.00E+02 2. 12E-03 O.OOE+OO 2. 12E-03 

8.00E+02 1.87E-03 O.OOE+OO l.87E-03 

9.00E+02 1. 66E-03 O.OOE+OO 1. 66E-03 

l.00E+03 1.47E-03 O.OOE+OO 1.47E-03 

2.00E+03 4.30E-04 O.OOE+OO 4.30E-04 

3.00E+03 1. 26E-04 O.OOE+OO 1. 26E-04 

4.00E+03 3.70E-05 O.OOE+OO 3.70E-05 

5.00E+03 1.09E-05 O.OOE+OO 1.09E-05 

6.00E+03 3. 18E-06 O.OOE+OO 3. 18E-06 

7.00E+03 9. 34E-07 O.OOE+OO 9. 34E-07 

8.00E+03 2. 74E-07 O.OOE+OO 2. 74E-07 

9.00E+03 8.03E-08 O.OOE+OO 8.03E-08 

1.00E+04 2. 36E-08 O.OOE+OO 2. 36E-08 

B-525 
INGESTION fl= 5.00&-02 HALFLIFK= 1.92&+03 DAYS COBALT 60 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 3.l7E-04 7.42E-04 

2.00E-Ol 1.43E-03 6.44E-03 

3.00E-Ol 2. 97E-03 2.03E-02 

4.00E-Ol 4. 63E-03 4. 27E-02 

S.OOE-Ol 6. 26E-03 7. 26E-02 

6.00E-Ol 7. 79E-03 1.OBE-Ol 

7.00E-Ol 9.l7E-03 1.49E-Ol 

B.OOE-Ol 1.04E-02 1.92E-Ol 

9.00E-Ol 1.lSE-02 2. 36E-Ol 

1.00E+OO 1.2SE-02 1.2SE-02 2.8lE-OI 2.8lE-Ol 

2.00E+OO S.S3E-03 1.80E-02 3.71E-Ol 6.S2E-Ol 

3.00E+OO 2.09E-03 2.01E-02 1. 84E-Ol B.37E-Ol 

4.00E+OO 1.lSE-03 2.l3E-02 7.S6E-02 9.l2E-Ol 

S.OOE+OO 8. 48E-04 2.2lE-02 2. 92E-02 9.4lE-OI 

6.00E+OO 7.lSE-04 2. 28E-02 1.llE-02 9.SlE-Ol 

7.00E+OO 6.30E-04 2. 34E-02 4. 26E-03 9.SSE-Ol 

8.00E+OO ' S.62E-04 2.40E-02 1.7lE-03 9.S7E-Ol 

9.00E+OO S.04E-04 2.4SE-02 7.S8E-04 9.S7E-Ol 

1.00E+Ol 4.S2E-04 2. 49E-02 3. 94E-04 9. S7E-Ol 

2.00E+Ol 1.6SE-04 2.7SE-02 7.06E-OS 9.SSE-Ol 

3.00E+Ol 7.2IE-OS 2.8SE-02 3.09E-OS 9.S2E-O] 

4.00E+Ol 4.lOE-OS 2. 89E-02 1. 76E-OS 9.49E-Ol 

S.OOE+Ol 2. 93E-OS 2.91E-02 1. 26E-OS 9.46E-Ol 

6.00E+Ol 2.40E-OS 2. 93E-02 1.03E-OS 9.42E-OI 

7.00E+Ol 2.09E-OS 2. 94E-02 B.9SE-06 9. 39E-Ol 

8.00E+Ol 1. 86E-OS 2.9SE-02 7. 97E-06 9. 36E-Ol 

9.00E+Ol 1.67E-OS 2.9SE-02 7.16E-06 9.32E-Ol 

1.00E+02 1.SlE-OS 2. 96E-02 6.46E-06 9. 29E-OI 

2.00E+02 6.14E-06 2. 95E-02 2. 63E-06 B.97E-Ol 

3.00E+02 3. 24E-06 2.B9E-02 1. 39E-06 B.65E-Ol 

4.00E+02 2.2lE-06 2.8lE-02 9. 45E-07 B.35E-Ol 

5.00E+02 1. 75E-06 2. 73E-02 7.49E-07 8.05E-Ol 

6.00E+02 1.49E-06 2.65E-02 6. 37E-07 7. 77E-Ol 

7.00E+02 1.30E-06 2.57E-02 5. 55E-07 7.49E-OI 

8.00E+02 1.14E-06 2. 49E-02 4.B9E-07 7.23E-Ol 

9.00E+02 1.OlE-06 2.4lE-02 4. 32E-07 6. 97E-Ol 

' ... 1.OOE+03 8.90E-07 2. 34E-02 3.8lE-07 6. 73E-Ol . " 2.00E+03 2.6lE-07 1. 67E-02 1.12E-07 4. 69E-Ol 

3.00E+03 7.6SE-OB 1.lBE-02 3. 28E-08 3. 27E-Ol 

4.00E+03 2. 25E-OB B.26E-03 O.OOE+OO 2. 28E-Ol 

B-526 
IRGESTION f l- 5.00E-02 STABLE NICKEL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 44E-02 9.84E-Ol 9. 98E-Ol 

2.00E-Ol 2.60E-02 9. 63E-Ol 9.89E-Ol 

3.00E-Ol 2. 99E-02 9.4lE-Ol 9.71E-Ol 

4.00E-Ol 2. 98E-02 9. 15E-Ol 9.45E-Ol 

5.00E-Ol 2.8lE-02 8. 83E-Ol 9.11E-Ol 

6.00E-Ol 2. 59E-02 8.46E-Ol 8.72E-Ol 

7.00E-Ol 2. 38E-02 8.06E-Ol 8.30E-Ol 

8.00E-Ol 2. 19E-02 7. 63E-Ol 7.8SE-Ol 

9.00E-Ol 2.04E-02 7. 19E-Ol 7. 39E-Ol 

1.00E+OO 1. 92E-02 6. 74E-Ol 6. 94E-Ol 

2.00E+OO 1.S3E-02 3.05E-Ol 3.20E-Ol 

3.00E+OO 1.50E-02 1.2lE-Ol 1. 36E-Ol 

4.00E+OO 1.S0E-02 4.60E-02 6.lOE-02 

5.00E+OO 1.S0E-02 1.71E-02 3.2lE-02 

6.00E+OO 1.49E-02 6. 34f;-03 2. 13E-02 

7.00E+OO 1. 49E-02 2. 34E-03 1. 73E-02 

8.00E+OO 1. 49E-02 8.6lE-04 1. 58E-02 

9.00E+OO 1.49E-02 3.l7E-04 1.52E-02 

1.OOE+Ol 1.49E-02 1.l7E-04 1. SOE-02 

2.00E+Ol 1.48E-02 O.OOE+OO 1.48E-02 

3.00E+Ol 1.47E-02 O.OOE+OO 1. 47E-02 

4.00E+Ol 1.47E-02 O.OOE+OO 1.47E-02 

S.OOE+Ol 1.46E-02 O.OOE+OO 1.46E-02 

6.00E+Ol 1.45E-02 O.OOE+OO 1.4SE-02 

7.00E+Ol 1. 44E-02 O.OOE+OO 1. 44E-02 

8.00E+Ol 1. 43E-02 O.OOE+OO 1.43E-02 

9.00E+Ol 1. 42E-02 O.OOE+OO 1. 42E-02 

1.00E+02 1.42E-02 O.OOE+OO 1. 42E-02 

2.00E+02 1. 34E-02 O.OOE+OO 1. 34E-02 

3.00E+02 1. 26E-02 O.OOE+OO 1. 26E-02 

4.00E+02 1. 19E-02 O.OOE+OO 1.19E-02 

5.00E+02 1. 12E-02 O.OOE+OO 1. 12E-02 

6.00E+02 1.06E-02 O.OOE+OO 1.06E-02 

7.00E+02 1.00E-02 O.OOE+OO 1.00E-02 

8.00E+02 9 •. 45E-03 O.OOE+OO . 9.45E-03 

9.00E+02 8. 92E-03 O.OOE+OO 8. 92E-03 " : .... , .. 1.OOE+03 8. 42E-03 O.OOE+OO 8. 42E-03 

2.00E+03 4. 73E-03 O.OOE+OO 4. 73E-03 

3.00E+03 2. 65E-03 O.OOE+OO 2.6SE-03 

4.00E+03 1.49E-03 O.OOE+OO 1. 49E-03 

S.OOE+03 8. 36E-04 O.OOE+OO 8. 36E-04 

7.00E+03 2. 63E-04 O.OOE+OO 2. 63E-04 

8.00E+03 1. 48E-04 O.OOE+OO 1.48E-04 

9.00E+03 8.30E-05 O.OOE+OO 8.30E-05 

1 •. 00E+04 4. 66E-05 O.OOE+OO 4. 66E-OS 

2.00E+04 1. 45E-07 O.OOE+OO 1.45E-07 

B-S27 
INGESTION fl= 5.00E-02 STABLE NICKEL 58 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.17E-03 6.06E-04 

2.00E-Ol 5.0lE-03 5. 83E-03 

3.00E-Ol 9. 93E-03 1.90E-02 

4.00E-Ol 1. 48E-02 4.07E-02 

5.00E-Ol 1.90E-02 6.99E-02 

6.00E-Ol 2. 25E-02 1.05E-Ol 

7.00E-Ol 2. 54E-02 1.45E-Ol 

8.00E-Ol 2. 76E-02 1.87E-Ol 

9.00E-Ol 2. 94E-02 2.3lE-Ol 

1.00E+OO 3.07E-02 3.07E-02 2. 76E-Ol 2. 76E-Ol 

2.00E+OO 4.04E-03 3. 47E-02 3. 69E-Ol 6.45E-Ol 

3.00E+OO 2. 63E-04 3.50E-02 1. 84E-Ol 8. 29E-Ol 

4.00E+OO 2.4SE-OS 3.S0E-02 7.52E-02 9.04E-Ol 

S.OOE+OO 9.63E-06 3.50E-02 2. 89E-02 9. 33E-Ol 

6.00E+OO 8.70E-06 3. SIE-02 1.08E-02 9. 44E-Ol 

7.00E+OO 8. 63E-06 3.SlE-02 4.00E-03 9.48E-Ol 

8.00E+OO 8. 63E-06 3. 51E-02 1.48E-03 9.49E-Ol 

9.00E+OO 8. 62E-06 3. 51E-02 5. 44E-04 9.50E-Ol 

1.OOE+Ol 8. 62E-06 3.5lE-02 2.00E-04 9.S0E-Ol 

2.00E+Ol 8.S7E-06 3. 52E-02 O.OOE+OO 9.S0E-Ol 

3.00E+Ol 8.S2E-06 3.S3E-02 O.OOE+OO 9. SOE-Ol 

4.00E+Ol 8. 47E-06 3.S3E-02 O.OOE+OO 9.50E-Ol 

S.OOE+Ol 8. 42E-06 3. S4E-02 O.OOE+OO 9.50E-Ol 

6.00E+Ol 8.37E-06 3.SSE-02 O.OOE+OO 9. SOE-Ol 

7.00E+Ol 8. 32E-06 3.S6E-02 O.OOE+OO 9.50E-Ol 

8.00E+Ol 8. 27E-06 3. 57E-02 O.OOE+OO 9.50E-Ol 

9.00E+Ol 8. 23E-06 3.58E-02 O.OOE+OO 9.50E-O! 

1.00E+02 8. 18E-06 3. 58E-02 O.OOE+OO 9. SOE-Ol 

2.00E+02 7. 72E-06 3.66E-02 O.OOE+OO 9.50E-Ol 

3.00E+02 7.29E-06 3. 74E-02 O.OOE+OO 9.50E-Ol 

4.00E+02 6. 88E-06 3.81E-02 O.OOE+OO 9.50E-Ol 

5.00E+02 6.49E-06 3. 88E-02 O.OOE+OO 9.S0E-O! 

7.00E+02 5. 78E-06 4.00E-02 O.OOE+OO 9.50E-Ol 

8.00E+02 S.46E-06 4.0SE-02 O.OOE+OO 9.S0E-Ol 

,', ';" , , 9.00E+02 S.lSE-06 4.1lE-02 O.OOE+OO 9.50E-Ol 

1.00E+03 4. 86E-06 4.l6E-02 O.OOE+OO 9.50E-Ol 

2.00E+03 2. 73E-06 4.S3E-OZ O.OOE+OO 9.50E-Ol 

3.00E+03 1.S3E-06 4.73E-02 O~OOE+OO 9.50E-Ol 

4.00E+03 8.60E-07 4.85E-02 O.OOE+OO 9.50E-Ol 

S.OOE+03 4. 83E-07 4. 92E-02 O.OOE+OO 9. SOE-O! 

7.00E+03 1. 52E-07 4. 97E-02 O.OOE+OO 9.50E-Ol 

8.00E+03 8.S4E-08 4. 99E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 4. 79E-08 4. 99E-02 O.OOE+OO 9. SOE-Ol 

1.OOE+04 2. 69E-08 S.OOE-02 O.OOE+OO 9. SOE-Ol 

B-S28 
INGESTION f 1- 5.00E-01 STABLE COPPER 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2. 44E-Ol 7.SSE-Ol 9. 99E-Ol 

2.00E-Ol 4. 13E-Ol S.82E-Ol 9. 94E-Gl 

J.OOE-Ol 4.7lE-0l S.13E-Ol 9. 84E-Ol 

4.00E-OI 4. 89E-Ol 4.79E-Gl 9. 69E-OI 

S.OOE-Ol 4. 94E-Ol 4.SSE-Ol 9. 49E-Ol 

6.00E-Ol 4.9SE-Ol 4.32E-Ol 9. 28E-Ol 

7.00E-0l 4.9SE-0l 4.09E-Ol 9.04E-Ol 

8.00E-Ol 4. 94E-OI 3.8SE-Ol 8. 79E-Ol 

9.00E-OI 4.9JE-OI 3.6IE-Ol 8.S5E-Ol 

1.OOE+OO 4. 92E-Ol 3.37E-Ol 8. JOE-Ol 

2.00E+OO 4. 84E-Ol 1. 49E-Ol 6.JJE-0l 

J.OOE+OO 4. 76E-Ol S.89E-02 S.3SE-Ol 

4.00E+OO 4. 68E-Ol 2. 23E-02 4.90E-OI 

S.OOE+OO 4.60E-Ol 8. 29E-OJ 4. 68E-Ol 

6.00E+OO 4.S2E-Ol 3.07E-OJ 4.SSE-Ol 

7.00E+OO 4. 44E-Ol I. BE-OJ 4.4SE-Ol 

8.00E+OO 4. J6E-OI 4.l6E-04 4.J7E-Ol 

9.00E+OO 4~29E-Ol 1.S3E-04 4. 29E:"'Ol 

1.OOE+OI 4.2lE-0l S.64E-OS 4.21E-Ol 

2.00E+Ol 3.S4E-Ol O.OOE+OO J.S4E-Ol 

3.00E+Ol 2. 98E-Ol O.OOE+OO 2. 98E-Ol 

4.00E+OI 2.SlE-Ol O.OOE+OO 2.SlE-Ol 

S.OOE+OI 2.1lE-0l O.OOE+OO 2.IIE-Ol 

6.00E+OI 1. 77E-Ol O.OOE+OO 1. 77E-OI 

7.00E+Ol 1. 49E-OI O.OOE+OO I. 49E-OI 

8.00E+Ol 1.2SE-OI O.OOE+OO 1.2SE-Ol 

9.00E+Ol I.OSE-OI O.OOE+OO 1. O~E-Ol 

I.OOE+02 8. 86E-02 O.OOE+OO 8. 86E-02 

2.00E+02 1.S7E-02 O.OOE+OO I. S7E-02 

3.00E+02 2. 77E-03 O.OOE+OO 2.77E-03 

4.00E+02 4.90E-04 O.OOE+OO 4.90E-04 

S.OOE+02 8. 67E-OS O.OOE+OO 8.67E-OS 

6.00E+02 1.SJE-OS O.OOE+OO I.SJE-OS 

7.00E+02 2.71E-06 O.OOE+OO 2.71E-06 

8.00E+02 4. 79E-07 O.OOE+OO 4. 79E-07 , 9.00E+02 8.47E-08 O.OOE+OO 8. 47E-08 ,"t, 

.. I.OOE+OJ 1.50E-08 O.OOE+OO 1.SOE-08 

B-529 
DIGESTION f l - 5.00E-QI STABLE COPPER. 63 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------~----------------------------------------------

SYSTEMIC NON-SYSTEHIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1. 85E-04 5.44E-04 

2.00E-01 7.77E-04 4. 77E-03 

3.00E-01 I.55E-03 1. 44E-02 

4.00E-OI 2.39E-03 2.90E-02 

5.00E-OI 3. 24E-03 4. 73E-02 

6.00E-01 4.lOE-03 6. 84E-02 

7.00E-OI 4. 96E-03 9.11E-02 

8.00E-OI 5.8IE-03 I.I5E-01 

9.00E-Ol 6.67E-03 1. 39E-OI 

1.00E+OO 7.52E-03 7.52E-03 1. 63E-01 l.63E-OI 

2.00E+OO 8. 46E-03 1.60E-02 1.88E-OI 3.51E-01 

3.00E+OO 8.31E-03 2. 43E-02 9.04E-02 4.41E-01 

4.00E+OO 8.17E-03 3. 25E-02 3. 66E-02 4. 78E-01 

5.00E+OO 8.03E-03 4.05E-02 l.40E-02 4. 92E-Ol 

6.00E+OO 7.89E-03 4.84E-02 5.23E-03 4.97E-01 

7.00E+OO 7.76E-03 5.6lE-02 1. 94E-03 4. 99E-01 

8.00E+OO 7. 62E-03 6. 38E-02 7.14E-04 5.00E-Ol 

9.00E+OO 7.49E-03 7.13E-02 2. 63E-04 5.00E-01 

1.OOE+Ol 7. 36E-03 7.86E-02 9. 68E-05 5.00E-Ol 

2.00E+01 6. 19E-03 1.46E-Ol O.OOE+OO 5.00E-Ol 

3.00E+Ol 5.2IE-03 2.02E-01 O.OOE+OO 5.00E-01 

4.00E+01 4. 38E-03 2.49E-OI O.OOE+OO 5.00E-01 

5.00E+Ol 3. 68E-03 2. 89E-01 O.OOE+OO 5.00E-OI 

6.00E+Ol 3.lOE-03 3.23E-01 O.OOE+OO 5.00E-01 

7.00E+Ol 2.60E-03 3.51E-01 O.OOE+OO 5.00E-01 

8.00E+OI 2. 19E-03 3. 75E-OI O.OOE+OO 5.00E-OI 

9.00E+OI 1.84E-03 3.95E-Ol O.OOE+OO 5.00E-01 

1.00E+02 1.55E-03 4.11E-OI O.OOE+OO 5.00E-01 

2.00E+02 2. 74E-04 4.84E-01 O.OOE+OO 5.00E-01 

3.00E+02 4. 84E-05 4.97E-01 O.OOE+OO 5.00E-OI 

4.00E+02 8. 56E-06 5.00E-01 O.OOE+OO 5.00E-01 

5.00E+02 1. 51E-06 5.00E-01 O.OOE+OO 5.00E-01 

6.00E+02 2. 68E-07 5.00E-Ol O.OOE+OO 5.00E-01 

7.00E+02 4. 74E-08 5.00E-01 O.OOE+OO 5.00E-01 

B-530 
INGESTION f 1- 5.00£-01 STABLB ZINC 66 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

. 1.00E-01 2. 44E-01 7. 55E-01 9. 99E-Ol 

2.00E-01 4. 13E-01 5. 82E-01 9. 95E-01 

3.00E-01 4.72E-01 5. 13E-Ol 9. 85E-Ol 

4.00E-01 4.90E-01 4. 79E-01 9.70E-Ol 

5.00E-Ol 4. 96E-01 4. 55E-01 9.51E-01 

6.00E-01 4. 97E-01 4. 32E-01 9~29E-Ol 

7.00E-01 4. 97E-01 4.09E-01 9.06E-Ol 

8.00E-01 4. 97E-01 3.85E-01 8. 82E-Ol 

9.00E-Ol 4.96E-Ol 3. 61E-01 8. 58E-Ol 

1.00E+00 4. 96E-Ol 3.37E-01 8. 33E-Ol 

2.00E+00 4.91E-01 1.49E-01 6.40E-Ol 

3.00E+00 4. 87E-01 5. 89E-02 5. 46E-Ol 

4.00E+00 4. 82E-01 2. 23E-02 5.05E-Ol 

5.00E+00 4. 78E-Ol 8.29E-03 4. 86E-Ol 

6.00E+00 4.74E-01 3.07E-03 4.77E-Ol 

7.00E+00 4.70E-Ol 1. 13E"':"03 4. 71E-Ol 

8.00E+00 4. 66E-01 4. 16E-04 4. 67E-Ol 

9.00E+00 4. 62E-01 1. 53E-04 4. 63E-01 

1.00E+01 4.59E-01 5. 64E-05 4. 59E-Ol 

2.00E+01 4. 27E-01 O.OOE+OO 4. 27E-Ol 

3.00E+01 4.03E-01 O.OOE+OO 4.03E-Ol 

4.00E+01 3.85E-01 O.OOE+OO 3. 85E-Ol 

5.00E+01 3.70E-01 O.OOE+OO 3.70E-Ol 

6.00E+01 3. 58E-01 O.OOE+OO 3. 58E-Ol 

7.00E+01 3. 47E-01 O.OOE+OO 3. 47E-01 

8.00E+01 3. 38E-01 O.OOE+OO 3. 38E-Ol 

9.00E+01 3. 31E-01 O.OOE+OO 3. 31E-Ol 

1.00E+02 3.23E-01 O.OOE+OO 3. 23E-Ol 

2.00E+02 2. 69E-01 O.OOE+OO 2. 69E-01 

3.00E+02 2. 26E-01 O.OOE+OO 2. 26E-Ol 

4.00E+02 1.90E-01 O.OOE+OO 1.90E-01 

5.00E+02 1.60E-01 O.OOE+OO 1.60E-Ol 

6.00E+02 1.35E-01 O.OOE+OO 1.35E-01 

7.00E+02 1. 13E-Ol O.OOE+OO 1.l3E-01 

8.00E+02 9. 52E-02 O.OOE+OO 9. 52E-02 

9.00E+02 8.01E-02 O.OOE+OO 8.01E-02 

1.00E+03 6. 74E-02 O.OOE+OO 6. 74E-02 

2.00E+03 1. 19E-02 O.OOE+OO 1. 19E-02 

3.00E+03 2. 12E-03 O.OOE+OO 2. 12E-03 

4.00E+03 3. 75E-04 O.OOE+OO 3. 75E-04 

5.00E+03 6. 66E-05 O.OOE+OO 6. 66E-05 

6.00E+03 1. 18E-05 O.OOE+OO 1. 18E-05 

7.00E+03 2.09E-06 O.OOE+OO 2.09E-06 

8.00E+03 3.71E-07 O.OOE+OO 3.71E-07 

9.00E+03 6. 57E-08 O.OOE+OO 6. 57E-08 

1.00E+04 1. 17E-08 O.OOE+OO 1. 17E-08 

B-531 
INGEsTION f 1- 5.00£-01 STABLE ZINC 66 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 2.S8E-OS 6.21E-04 

2.00E-Ol 1.08E-04 S.09E-03 

3.00E-Ol 2.16E-04 1.SOE-02 

4.00E-Ol 3. 32E-04 3.00E-02 

S.OOE-Ol 4.S0E-04 4.87E-02 

6.00E-Ol S.6BE-04 7.0lE-02 

7.00E-Ol 6. 87E-04 9. 32E-02 

8. OOE-O1 B.OSE-04 1.17E-Ol 

9.00E-Ol 9.23E-04 l.42E-Ol 

1.OOE+OO 1.04E-03 1.04E-03 1. 66E-Ol l.66E-Ol 

2.00E+OO 1.16E-03 2.20E-03 1.92E-Ol 3.S7E-Ol 

3.00E+OO 1.12E-03 3. 32E-03 9. 37E-02 4.SlE-Ol 

4.00E+OO 1.09E-03 4.4lE-03 3.9BE-02 4.9lE-Ol 

S.OOE+OO 1.06E-03 S.47E-03 1.72E-02 S.08E-Ol 

6.00E+OO 1.03E-03 6. 49E-03 B.3lE-03 S.l6E-0l 

7.00E+OO 9.97E-04 7.49E-03 4. 93E-03 5.2lE-Ol 

B.OOE+OO 9.6BE-04 8. 46E-03 3. 62E-03 S.2SE-Ol 

9.00E+OO 9.40E-04 9.40E-03 3.0BE-03 S.28E-Ol 

1.OOE+Ol 9.l4E-04 1.03E-02 2. 84E-03 S.3lE-Ol 

2.00E+Ol 6.90E-04 1.B2E-02 2.07E-03 S.S4E-Ol 

3.00E+Ol 5. 32E-04 2.4lE-02 1.60E-03 S.72E-Ol 

4.00E+Ol 4.19E-04 2. 88E-02 1.26E-03 S.B6E-Ol 

5.00E+Ol 3. 39E-04 3.2SE-02 1.02E-03 S.98E-Ol 

6.00E+Ol 2.BlE-04 3.S6E-02 8. 43E-04 6.07E-Ol 

7.00E+Ol 2.40E-04 3.B2E-02 7.l9E-04 6.l4E-Ol 

8.00E+Ol 2.lOE-04 4.04E-02 6.29E-04 6.2lE-Ol 

9.00E+Ol 1.BBE-04 4. 24E-02 S.63E-04 6. 27E-Ol 

1.OOE+02 1.7lE-04 4.4lE-02 S.14E-04 6. 32E-Ol 

2.00E+02 1.17E-04 5. 77E-02 3.S2E-04 6.73E-Ol 

3.00E+02 9. 79E-05 6. BSE-02 2. 94E-04 7.0SE-Ol 

4.00E+02 B.24E-OS 7. 74E-02 2.47E-04 7. 32E-Ol 

S.OOE+02 6. 93E-OS 8.S0E-02 2.0BE-04 7.SSE-Ol 

6.00E+02 S.83E-OS 9.l3E-02 1. 75E-04 7. 74E':'Ol 

7.00E+02 4.90E-OS 9. 67E-02 1. 47E-04 7.90E-Ol 

B.OOE+02 4.12E-OS 1.OlE-Ol 1.24E-04 8.04E-Ol 

9.00E+02 3. 47E-OS 1.OSE-Ol 1.04E-04 8.lSE-Q1 

1.OOE+03 2. 92E-OS 1.OBE-Ol B.75E-OS B.24E-Ol 

2.00E+03 S.l7E-06 1.22E-Ol 1. SSE-OS B.66E-Ol 

3.00E+03 9.l7E-07 1.24E-Ol 2.7SE-06 8.73E-Ol 

4.00E+03 l.63E-07 1.2SE-Ol 4.B8E-07 8.7SE-Ol 

5.00E+03 2.BBE-08 1.2SE-Ol 8. 64E-08 B.75E-Ol 

B-532 
INGESTION f1= 5.00E-ol BALFLIFE= 2.44E+02 DAYS ZIHC 65 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------~---------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 2. 44E-01 7.55E-01 9.99E-01 

2.00E-01 4. 13E-01 5. 82E-01 9. 94E-01 

3.00E-01 4.72E-01 5. 12E-01 9. 84E-01 

4.00E-ol 4.90E-01 4. 79E-01 9. 69E-01 

5.00E-01 4.95E-01 4. 55E-01 9.50E-01 

6.00E-01 4. 96E-01 4. 32E-01 9.28E-01 

7.00E-01 4.96E-01 4.08E-01 9.04E-01 

8.00E-01 4. 96E-01 3. 84E-01 8.80E-01 

9.00E-01 4. 95E-01 3.60E-01 8. 55E-01 

1.00E+00 4. 94E-01 3. 36E-01 8.31E-01 

2.00E+00 4. 88E-01 1. 48E-01 6. 37E-01 

3.00E+00 4. 83E-01 5. 84E-02 5.41E-01 

4.00E+00 4. 77E-01 2.20E-02 4. 99E-01 

5.00E+00 4.71E-01 8. 18E-03 4.80E-01 

6.00E+00 4. 66E-01 .3.0lE-03 4. 69E-01 

7.00E+00 4.61E-01 1. 11E-03 4. 62E-01 

8.00E+00 4.56E-01 4.07E-04 4. 56E-01 

9.00E+00 4.51E-01 1. 49E-04 4.51E-01 

1.00E+01 4.46E-01 5. 48E-05 4.46E-01 

2.00E+01 4.04E-01 O.OOE+OO 4.04E-01 

3.00E+01 3.70E-01 O.OOE+OO 3.70E-01 

4.00E+01 3.43E-01 O.OOE+OO 3. 43E-01 

5.00E+01 3.21E-01 O.OOE+OO 3.21E-01 

6.00E+01 3.02E-01 O.OOE+OO 3.02E-01 

7.00E+01 2. 85E-01 O.OOE+OO 2. 85E-01 

8.00E+01 2.70E-01 O.OOE+OO 2.70E-01 

9.00E+01 2. 56E-01 O.OOE+OO 2. 56E-01 

1.00E+02 2. 43E-01 O.OOE+OO 2. 43E-01 

2.00E+02 1. 52E-01 O.OOE+OO 1.52E-01 

3.00E+02 9. 64E-02 O.OOE+OO 9. 64E-02 

4.00E+02 6.1OE-02 O.OOE+OO 6.1OE-02 

5.00E+02 3. 86E-02 O.OOE+OO 3. 86E-02 

6.00E+02 2. 45E-02 O.OOE+OO 2. 45E-02 

7.00E+02 1. 55E-02 O.OOE+OO 1. 55E-02 

8.00E+02 9.80E-03 O.OOE+OO 9.80E-03 

9.00E+02 6.21E-03 O.OOE+OO 6.21E-03 

1.00E+03 3. 93E-03 O.OOE+OO 3. 93E-03 

2.00E+03 4.06E-05 O.OOE+OO 4.06E-05 

3.00E+03 4.20E-07 O.OOE+OO 4.20E-07 

B-533 
INGESTION f1= 5.00R-ol HALFLII'R- 2.44E+02 DAYS ZINC 65 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 2.S8E-OS 6.2lE-04 

2.00E-Ol 1.08E-04 S.09E-03 

3.00E-Ol 2.l6E-04 1.SOE-02 

4.00E-Ol 3.3lE-04 2. 99E-02 

S.·OOE-Ol 4.49E-04 4.86E-02 

6.00E-Ol S.67E-04 6. 99E-02 

7.00E-Ol 6. 86E-04 9.30E-02 

8.00E-Ol 8.03E-04 1.17E-Ol 

9.00E-Ol 9.2lE-04 1.4lE-Ol 

1.OOE+OO 1.04E-03 1.04E-03 1.6SE-Ol 1.6SE-Ol 

2.00E+OO 1.lSE-03 2.l8E-03 1.9lE-0l 3.SSE-Ol 

3.00E+OO 1.llE-03 3. 29E-03 9. 29E-02 4.47E-Ol 

4.00E+OO 1.OSE-03 4. 36E-03 3.94E-02 4.8SE-Ol 

S.OOE+OO I.04E-03 S.39E-03 1. 69E-02 S.OlE-Ol 

6.00E+OO 1. OlE-03 6.3SE-03 S.17E-03 S.08E-Ol 

7.00E+OO 9.77E-04 7. 34E-03 4. 83E-03 S.llE-Ol 

8.00E+OO 9. 46E-04 8. 27E-03 3. S4E-03 S.l3E-Ol 

9.00E+OO 9.l7E-04 9.16E-03 3.0lE-03 S.lSE-Ol 

1.OOE+Ol 8. 88E-04 I.OOE-02 2. 76E-03 S.16E-Ol 

2.00E+Ol 6.S2E-04 1.72E-02 1. 96E-03 S.24E-Ol 

3.00E+Ol 4.8SE-04 2. 22E-02 1.47E-03 S.26E-Ol 

4.00E+Ol 3. 74E-04 2.S7E-02 1.12E-03 S.23E-Ol 

S.OOE+Ol 2. 94E-04 2. 82E-02 8.8lE-04 S.18E-Ol 

6.00E+Ol 2. 37E-04 3.00E-02 7.11E-04 S.12E-Ol 

7.00E+Ol 1. 96E-04 3.l3E-02 S.89E-04 S.04E-Ol 

8.00E+Ol 1. 67E-04 3. 22E-02 S.OlE-04 4.9St:-Ol 

9.00E+Ol 1.4SE-04 3. 28E-02 4.36E-04 4.86E-Ol 

1.OOE+02 1. 29E-04 3. 32E-02 3. 87E-04 4. 76E-Ol 

2.00E+02 6.6SE-OS 3. 27E-02 2.00E-04 3.SlE-Ol 

3.00E+02 4.l8E-OS 2. 92E-02 1.2SE-04 3.0lE-Ol 

4.00E+02 2.64E-OS 2.4SE-02 7.93E-OS 2.3SE-Ol 

S.OOE+02 I. 67E-OS 2.0SE-02 S.02E-OS 1. 82E-Ol 

6.00E+02 I.06E-OS 1. 66E-02 3.l8E-OS 1.4lE-Ol 

7.00E+02 6.70E-06 1. 32E-02 2. OlE-OS I.08E-Ol 

8.00E+02 4. 24E-06 1.04E-02 1.27E-OS 8.27E-02 

9.00E+02 2. 69E-06 8.l3E-03 8.06E-06 6.31E-02 

1.OOE+03 1.70E-06 6.3lE-03 S.lOE-06 4.8lE-02 

2.00E+03 I. 76E-08 4.lSE-04 S.28E-08 2. 94E-03 

B-S34 
INGESTION f l- I.OOE-03 STABLE GALLIUM 69 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2.96E-04 9. 99E-Ol 9.99E-Ol 

2.00E-Ol S.89E-04 9.93E-Ol 9.94E-Ol 

3.00E-Ol 7.S4E-04 9.80E-Ol 9.8lE-Ol 

4.00E-Ol 8.37E-04 9.S8E-Ol 9.S8E-Ol 

S.OOE-Ol 8.7SE-04 9. 27E-OI 9.28E-OI 

6.00E-Ol 8. 89E-04 8.9IE-Ol 8. 92E-Ol 

7.00E-Ol 8.90E-04 8.S0E-Ol 8.SlE-Ol 

8.00E-Ol 8. 84E-04 8.0SE-Ol 8.06E-Ol 

9.00E-Ol 8. 74E-04 7.S9E-OI 7.60E-Ol 

1.00E+OO 8. 64E-04 7.l3E-Ol 7.l4E-Ol 

2.00E+OO 7.70E-04 3. 23E-OI 3. 24E-Ol 

3.00E+OO 7.17E-04 1.29E-Ol 1. 29E-OI 

4.00E+OO 6. 86E-04 4. 88E-02 4.9SE-02 

S.OOE+OO 6.66E-04 1. 82E-02 1. 89E-02 

6.00E+OO 6.SlE-04 6. 74E-03 7. 39E-03 

7.00E+OO 6.40E-04 2. 48E-03 3.l2E-03 

8.00E+OO 6.30E-04 9.lSE-04 1.S4E-03 

9.00E+OO 6.20E-04 3. 37E-04 9.S7E-04 

I.OOE+Ol 6.12E-04 1. 24E-04 7.3SE-04 

2.00E+Ol S.32E-04 O.OOE+OO ·S.32E-04 

3.00E+OI 4. 63E-04 O.OOE+OO 4. 63E-04 

4.00E+OI 4.03E-04 O.OOE+OO 4.03E-04 

S.OOE+Ol 3.SIE-04 O.OOE+OO 3.SlE-04 

6.00E+Ol 3.06E-04 O.OOE+OO 3.06E-04 

7.00E+Ol 2.66E-04 O.OOE+OO 2. 66E-04 

8.00E+OI 2. 32E-04 O.OOE+OO 2. 32E-04 

9.00E+OI 2.02E-04 O.OOE+OO 2.02E-04 

1.00E+02 1. 76E-04 O.OOE+OO 1. 76E-04 

2.00E+02 4. 39E-05 O.OOE+OO 4. 39E-05 

3.00E+02 1.lOE-OS O.OOE+OO 1. IOE-OS 

4.00E+02 2. 75E-06 O.OOE+OO 2. 75E-06 

S.OOE+02 6. 87E-07 O.OOE+OO 6. 87E-07 

6.00E+02 1.72E-07 O.OOE+OO 1.72E-07 

7.00E+02 4. 29E-08 O.OOE+OO 4;29E-08 

8.00E+02 I.07E-08 O.OOE+OO I.07E-08 

.. 

B-S35 
INGESTION f l= l.OOE-03 STABLE GALLIDK 69 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------~-~---- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUI.fULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 64E-06 6.10E-04 

2.00E-OI 1.22E-05 5.90E-03 

3.00E-01 2. 62E-05 1.93E-02 

4.00E-Ol 4.2IE-05 4.l6E-02 

5.00E-Ol 5. 86E-05 7.l7E-02 

6.00E-01 7.49E-OS 1.08E-Ol 

7.00E-01 9.06E-05 1.49E-Ol 

B.OOE-Ol 1.06E-04 1. 94E-Ol 

9.00E-OI 1.20E-04 2.40E-01 

1.OOE+OO 1. 33E-04 1. 33E-04 2. 86E-Ol 2.B6E-Ol 

2.00E+OO 9. 67E-05 2.30E-04 3. 89E-01 6. 76E-Ol 

3.00E+OO 5.3lE-05 2. 83E-04 1. 95E-01 8.70E-01 

4.00E+OO 3. lIE-OS 3.14E-04 7. 98E-02 9.S0E-Ol 

5.00E+OO 2.0IE-05 3. 34E-04 3.06E-02 9.8lE-Ol 

6.00E+OO 1.4SE-05 3. 49E-04 1.l5E-02 9. 92E-Ol 

7.00E+OO 1.l6E-05 3.60E-04 4.2SE-03 9. 97E-Ol 

8.00E+OO 1. OlE-OS 3.70E-04 1. S7E-03 9. 98E-01 

9.00E+OO 9. 33E-06 3.80E-04 S.78E-04 9. 99E-Ol 

1.OOE+Ol 8.87E-06 3. 88E-04 2.l3E-04 9.99E-01 

2.00E+OI 7. 43E-06 4. 68E-04 O.OOE+OO 9. 99E-Ol 

3.00E+Ol 6. 46E-06 5.37E-04 O.OOE+OO 9. 99E-OI 

4.00E+OI 5. 63E-06 5. 97E-04 O.OOE+OO 9. 99E-01 

5.00E+Ol 4.90E-06 6. 49E-04 O.OOE+OO 9. 99E-01 

6.00E+Ol 4.27E-06 6. 94E-04 O.OOE+OO 9.99E-Ol 

7.00E+Ol 3.71E-06 7. 34E-04 O.OOE+OO 9. 99E-Ol 

8.00E+Ol 3. 23E-06 7. 68E-04 O.OOE+OO 9. 99E-Ol 

9.00E+Ol 2.8lE-06 7. 98E-04 O.OOE+OO 9. 99E-Ol 

1.OOE+02 2. 45E-06 8. 24E-04 O.OOE+OO 9.99E-OI 

2.00E+02 6.13E-07 9.56E-04 O.OOE+OO 9. 99E-Ol 

3.00E+02 I. 53E-07 9. 89E-04 O.OOE+OO 9. 99E-OI 

4.00E+02 3.83E-08 9.97E-04 O.OOE+OO 9. 99E-Ol 

B-536 
INGESTION £1= 1.00E+OO STABLE GERHABIUK 73 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 8.11E-01 9.07E-02 9.02E-01 

2.00E-01 7. 64E-01 8. 23E-03 7. 72E-01 

3.00E-01 6. 64E-01 7. 48E-04 6. 64E-01 

4.00E-01 5.77E-01 6. 86E-05 5. 77E-01 

5.00E-01 5.06E-01 7.02E-06 5.06E-01 

6.00E-01 4.47E-01 1.38E-06 4. 47E-01 

7.00E-01 3.98E-01 8.30E-07 3. 98E-01 

8.00E-01 3.57E-01 7. 35E-07 3. 57E-01 

9.00E-01 3. 23E-01 6. 83E-07 3. 23E-01 

1.00E+00 2. 93E-01 6. 35E-07 2. 93E-01 

2.00E+00 1.31E-01 2. 76E-07 1.31E-Ol 

3.00E+00 6. 45E-02 1.08E-07 6. 45E-02 

4.00E+00 3. 22E-02 4.09E-08 3. 22E-02 

5.00E+00 1.61E-02 1. 52E-08 1.61E-02 

6.00E+00 8.05E-03 O.OOE+OO 8.05E-03 

7.00E+00 4.03E-03 O.OOE+OO 4.03E-03 

8.00E+00 2.01E-03 O.OOE+OO 2.01E-03 

9.,00E+00 1.01E-03 O.OOE+OO 1.0IE-03 

1.00E+01 5.04E-04 O.OOE+OO 5.04E-04 

2.00E+Ol 4. 92E-07 O.OOE+OO 4. 92E-07 

B-537 
INGESTION £1= 1.00E+OO STABLE GKRKANIUM 73 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------.----------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 9. 84E-02 4.12E-09 

2.00E-Ol 2.28E-Ol 2.10E-08 

3.00E-Ol 3. 36E-OI 4. 92E-08 

4.00E-Ol 4. 23E-Ol 8. 57E-08 

S.OOE-Ol 4.94E-Ol 1. 28E-07 

6.00E-Ol 5.53E-Ol 1. 73E-07 

7.00E-Ol 6.02E-Ol 2.2IE-07 

8.00E-Ol 6.43E-Ol 2. 69E-07 

9.00E-Ol 6. 77E-Ol 3.17E-07 

1.OOE+OO 7.07E-OI 7.07E-Ol 3. 65E-07 3. 65E-07 

2.00E+OO 1.62E-Ol 8. 69E-Ol 3. 59E-07 7. 24E-07 

3.00E+OO 6. 64E-02 9.35E-Ol 1. 68E-07 8. 92E-07 

4.00E+OO 3. 23E-02 9.68E-Ol 6.74E-08 9. 59E-07 

S.OOE+OO 1.6lE-02 9. 84E-Ol 2. 57E-08 9. 85E-07 

6.00E+OO 8.0SE-03 9. 92E-Ol O.OOE+OO 9.94E-07 

7.00E+OO 4.03E-03 9. 96E-OI O.OOE+OO 9. 98E-07 

8.00E+OO 2.0lE-03 9.98E-Ol O.OOE+OO 9.99E-07 

9.00E+OO 1.OIE-03 9.99E-Ol O.OOE+OO 1.OOE-06 

1.OOE+Ol S.03E-04 9. 99E-Ol O.OOE+OO 1.OOE-06 

2.00E+Ol 4. 92E-07 1.OOE+OO O.OOE+OO I.OOE-06 

B-S38 
INGESTION £1= 5.00E-ol STABLE ARSENIC 75 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2. 32E-Ol 7. 55E-Ol 9.SSE-Ol 

2.00E-Ol 3.6SE-OI 5.S2E-OI 9.50E-OI 

3.00E-Ol 3.90E-Ol 5.l3E-Ol 9.02E-OI 

4.00E-Ol 3. 75E-OI 4. 79E-OI S.54E-OI 

5.00E-Ol 3. 52E-OI 4. 55E-OI S.07E-Ol 

6.00E-Ol 3.30E-OI 4. 32E-OI 7.63E-Ol 

7.00E-Ol 3.12E-OI 4.09E-OI 7.2lE-Ol 

S.OOE-OI 2. 96E-OI 3.S5E-OI 6.SlE-Ol 

9.00E-OI 2.82E-0l 3.6IE-Ol 6.43E-OI 

I.OOE+OO 2.7IE-OI 3.37E-Ol 6.0SE-OI 

2.00E+OO 2.0SE-OI I. 49E-Ol 3.57E-Ol 

3.00E+OO 1. 78E-Ol 5. 89E-02 2. 36E-Ol 

4.00E+OO 1. 58E-Ol 2. 23E",:,,02 1.80E-Ol 

5.00E+OO 1. 44E-OI 8. 29E-03 I. 52E-Ol 

6.00E+OO 1. 32E-Ol 3.07E-03 1. 35E-Ol 

7.00E+OO 1. 22E-OI 1.13E-03 1. 23E-Ol 

8.00E+OO 1.14E-Ol 4.l6E-04 1.14E~Ol 

9.00E+OO 1.06E-Ol 1. 53E-04 1.06E-Ol 

1.OOE+Ol 9. 85E-02 5. 64E-05 9. 86E-02 

2.00E+Ol 4. 92E-02 O.OOE+OO 4. 92E-02 

3.00E+Ol 2. 46E-02 O.OOE+OO 2.46E-02 

4.00E+Ol 1. 23E-02 O.OOE+OO 1. 23E-02 

5.00E+Ol 6.l5E-03 O.OOE+OO 6.l5E-03 

6.00E+Ol 3.08E-03 O.OOE+OO 3.0SE-03 

7.00E+Ol 1. 54E-03 O.OOE+OO 1. 54E-03 

S.OOE+Ol 7. 69E-04 O.OOE+OO 7. 69E-04 

9.00E+Ol 3. 85E-04 O.OOE+OO 3. 85E-04 

I.OOE+02 1. 92E-04 O.OOE+OO 1. 92E-04 

2.00E+02 1.S8E-07 O.OOE+OO 1. 88E-07 

B-539 
INGESTION fl= 5.00£-01 STABLE ARSENIC 75 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ---------------------- '< 

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 18E-02 5. 44E-04 

2.00E-Ol 4. 55E-02 4.77E-03 

3.00E-Ol 8. 33E-02 1. 44E-02 

4.00E-Ol 1. 17E-Ol 2.90E-02 

5.00E-Ol 1.45E-Ol 4. 73E-02 

6.00E-Ol 1. 69E-Ol 6. 84E-02 

7.00E-Ol 1. 88E-Ol 9. 11E-02 

8.00E-Ol 2.04E-Ol 1. 15E-Ol 

9.00E-Ol 2. 18E-Ol 1. 39E-Ol 

1.00E+00 2. 29E-Ol 2. 29E-Ol 1. 63E-Ol 1. 63E-Ol 

2.00E+00 6. 29E-02 2.92E-Ol 1.88E-Ol 3.51E-Ol 

3.00E+00 3.02E-02 3. 22E-Ol 9.04E-02 4.41E-Ol 

4.00E+00 1. 96E-02 3.42E-Ol 3.66E-02 4. 78E-Ol 

5.00E+00 1. 44E-02 3. 56E-Ol 1.40E-02 4. 92E-Ol 

6.00E+00 1. 15E-02 3.68~-01 5.23E-03 4. 97E-Ol 

7.00E+00 9.80E-03 3. 78E-Ol 1. 94E-03 4. 99E-Ol 

8.00E+00 8. 66E-03 3. 86E-Ol 7.14E-04 5.00E-Ol 

9.00E+00 7. 84E-03 3.94E-Ol 2. 63E-04 5.00E-Ol 

1.00E+Ol 7.20E-03 4.01E-Ol 9. 68E-05 5.00E-Ol 

2.00E+Ol 3. 53E-03 4.51E-Ol O.OOE+OO 5.00E-Ol 

3.00E+Ol 1.77E-03 4. 75E-Ol O.OOE+oo 5.00E-Ol 

4.00E+Ol 8. 83E-04 4.88E-Ol O.OOE+OO 5.00E-Ol 

5.00E+Ol 4. 41E-04 4. 94E-Ol O.OOE+OO 5.00E-Ol 

6.00E+Ol 2.21E-04 4. 97E-Ol O.OOE+OO 5.00E-Ol 

7.00E+Ol 1.10E-04 4. 98E-Ol O.OOE+oo 5.00E-Ol 

8.00E+Ol 5. 52E-05 4.99E-Ol O.OOE+OO 5.00E-Ol 

9.00E+Ol 2. 76E-05 5.00E-01 O.OOE+oo 5.00E":'01 

1.00E+02 1. 38E-05 5.00E-Ol O.OOE+OO 5.00E-Ol 

2.00E+02 1. 35E-08 5.00E-Ol O.OOE+OO 5.00E-Ol 

B-540 
INGESTION £1= 8.00E-ol STABLE SELENIUM 78 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5.95E-Ol 4.03E-01 9.99E-01 

2.00E-01 7. 72E-Ol 2. 22E-Ol 9. 94E-01 

3.00E-01 7.91E-01 1.95E-01 9. 86E-Ol 

4.00E-01 7.91E-01 1. 86E-01 9. 77E-01 

5.00E-01 7.89E-01 1. 77E-01 9. 66E-01 

6.00E-01 7. 86E-01 1. 68E-01 9. 54E-01 

7.00E-01 7. 84E-01 1. 59E-01 9.42E-01 

8.00E-01 7.81E-01 1.49E-01 9.30E-01 

9.00E-01 7. 79E-01 1.40E-01 9. 18E-01 

1.00E+00 7. 76E-01 1.30E-01 9.06E-01 

2.00E+00 7. 54E-01 5.70E-02 8.llE-01 

3.00E+00 7. 34E-01 2. 24E-02 7. 57E-01 

4.00E+00 7.17E-01 8. 46E-03 7.26E-01 

5.00E+00 7.02E-01 3. 15E-03 7.05E-01 

6.00E+00 6. 89E-01 1. 16E-03 6.90E-01 

7.00E+00 6. 76E-01 4. 29E-04 6. 77E-01 

8.00E+00 6.65E-01 1.58E-04 6. 65E-01 

9.00E+00 6. 54E-01 5.81E-05 6. 54E-01 

1.00E+01 6.45E-01 2. 14E-05 6.45E-01 

2.00E+01 5. 68E-01 O.OOE+OO 5. 68E-01 

3. o ClE+O 1 5.09E-01 O.OOE+OO 5.09E-01 

4.00E+01 4.60E-Ol O.OOE+OO 4.60E-01 

5.00E+01 4. 19E-01 O.OOE+OO 4. 19E-01 

6.00E+01 3. 83E-01 O.OOE+OO 3. 83E-01 

7.00E+01 3. 53E-01 O.OOE+OO 3. 53E-01 

8.00E+01 3. 27E-01 O.OOE+OO 3. 27E-01 

9.00E+01 3.04E-Ol O.OOE+OO 3.04E-01 

1.00E+02 2. 84E-01 O.OOE+OO 2. 84E-01 

2.00E+02 1.62E-01 O.OOE+OO 1. 62E-01 

3.00E+02 1.00E-01 O.OOE+OO 1.00E-01 

4.00E+02 6.31E-02 O.OOE+OO 6. 31E-02 

5.00E+02 3.97E-02 O.OOE+OO 3. 97E-02 

6.00E+02 2.50E-02 O.OOE+OO 2.50E-02 

7.00E+02 1. 58E-02 O.OOE+OO 1. 58E-02 

8.00E+02 9.93E-03 O.OOE+OO 9. 93E-03 

9.00E+02 6. 26E-03 O.OOE+OO 6. 26E-03 

1.00E+03 3. 94E-03 O.OOE+OO 3.94E-03 

2.00E+03 3.88E-05 O.OOE+OO 3. 88E-05 

3.00E+03 3. 83E-07 O.OOE+OO 3. 83E-07 

B-541 
INGESTION fl"" 8.00E-Ol STABLE SELENIUM 78 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.03E-03 4.05E-04 

2.00E-Ol 3. 46E-03 2. 93E-03 

3.00E-Ol 6.l2E-03 7.86E-03 

4.00E-Ol 8.17E-03 1.46E-02 

5.00E-OI , 1.14E-02 2. 27E-02 

6.00E-Ol 1.40E-02 3.l6E-02 

7.00E-OI 1.6SE-02 4.lOE-02 

8.00E-Ol 1.90E-02 S.07E-02 

9.00E-OI 2.l4E-02 6.03E-02 

1.OOE+OO 2. 39E-02 2. 39E-02 6. 98E-02 6. 98E-02 

2.00E+OO 2.23E-02 4. 62E-02 7.33E-02 1.43E-Ol 

3.00E+OO 1.94E-02 6.S6E-02 3. 46E-02 1. 78E-Ol 

4.00E+OO 1.70E-02 8.26E-02 1.39E-02 1. 92E-Ol 

S.OOE+OO I.SlE-02 9. 78E-02 S.3lE-03 1. 97E-Ol 

6.00E+OO 1.36E-02 1.1IE-Ol 1. 98E-03 1. 99E-Ol 

7.00E+OO 1.24E-02 1. 24E-Ol 7.3SE-04 2.00E-Ol 

8.00E+OO 1.13E-02 1.3SE-Ol 2.7lE-04 2.00E-Ol 

9.00E+OO 1.OSE-02 1. 46E-Ol 9. 98E-OS 2.00E-Ol 

1.OOE+Ol 9.8lE-03 1.55E-Ol 3. 67E-05 2.00E-Ol 

2.00E+Ol 6. 62E-03 2. 32E-Ol O.OOE+OO 2.00E-Ol 

3.00E+Ol S.38E-03 2.9lE-0l O.OOE+OO 2.00E-Ol 

4.00E+Ol 4. 52E-03 3.40E-Ol O.OOE+OO 2.00E-Ol 

S.OOE+Ol 3. 83E-03 3.8lE-Ol O.OOE+OO 2.00E-Ol 

6.00E+Ol 3. 28E-03 4.17E-Ol O.OOE+OO 2.00E-Ol 

7.00E+Ol 2. 83E-03 4.47E-Ol O.OOE+OO 2.00E-Ol 

8.00E+Ol 2. 46E-03 4.73E-Ol O.OOE+OO 2.00E'-Ol 

9.00E+Ol 2.16E-03 4.96E-Ol O.OOE+OO 2.00E-Ol 

1.OOE+02 1.9lE-03 5.l6E-Ol O.OOE+OO 2.00E-OI 

2.00E+02 8.09E-04 6. 38E-Ol O.OOE+OO 2.00E-0l 

3.00E+02 4.7lE-04 7.00E-Ol O.OOE+OO 2.00E-Ol 

4.00E+02 2.93E-04 7.37E-Ol O.OOE+OO 2.00E-Ol 

5.00E+02 1. 84E-04 7.60E-Ol O.OOE+OO 2.00E-Ol 

6.00E+02 1.16E-04 7. 75E-Ol O.OOE+OO 2.00E-Ol 

7.00E+02 7.30E-.05 7. 84E-Ol O.OOE+OO 2.00E-Ol . '.' -:, 8.00E+02 4.60E-OS 7.90E-Ol O.OOE+OO 2.00E-Ol 

9.00E+02 2.90E-OS 7. 94E-Ol O.OOE+OO 2.00E-Ol 

1.OOE+03 1. 83E-05 7.96E-Ol O.OOE+OO 2.00E-Ol 

2.00E+03 1.80E-07 8.00E-Ol O.OOE+OO 2.00E-Ol 

B-542 
DIGESTION f 1'- 1.00£+00 STABIB BROMINE 79 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 9.0SE-OI 9.07E-02 . 9.96E-OI 

2.00E-Ol 9. BlE-OI 8. 23E-03 9. 89E-OI 

3.00E-OI 9. 82E-Ol 7. 48E-04 9.82E-OI 

4.00E-OI 9.7SE-Ol 6.B6E-OS 9.7SE-Ol 

S.OOE-Ol 9.69E-OI 7.02E-06 9. 69E-Ol 

6.00E-Ol 9. 62E-Ol 1.3BE-06 9. 62E-Ol 

7.00E-Ol 9.SSE-Ol B.30E-07 9.SSE-Ol 

8.00E-Ol 9. 49E-Ol 7. 35E-07 9. 49E-Ol 

9.00E-Ol 9. 42E-Ol 6. 83E-07 9. 42E-Ol 

1.OOE+OO 9. 36E-Ol 6. 35E-0,7 9. 36E-Ol , 2.00E+OO B.73E-Ol 2. 76E-07 B.73E-Ol 

3.00E+OO B.15E-OI 1.08E-07 B.lSE-Ol 

4.00E+OO 7.60E-Ol 4.09E-OB 7.60E-Ol 

5.00E+OO 7.09E-Ol 1.S2E-OB 7.09E-Ol 

6.00E+OO 6. 62E-Ol O.OOE+OO 6.62E-Ol 

7.00E+OO 6.17E-0l O.OOE+OO 6. 17E-ol 

B.OOE+OO 5. 76E-Ol O.OOE+OO S.76E-Ol 

9.00E+OO S.3BE-Ol O.OOE+OO 5. 38E-OI 

1.OOE+Ol S.02E-Ol O.OOE+OO 5.02E-Ol 

2.00E+Ol 2.51E-Ol O.OOE+OO 2.5IE-OI 

3.00E+Ol 1. 25E-Ol O.OOE+OO 1.25E-0l 

4.00E+Ol 6. 27E-02 O.OOE+OO 6. 27E-02 

5.00E+Ol 3.14E-02 O.OOE+OO 3.14E-02 

6.00E+Ol 1. 57E-02 O.OOE+OO 1.57E-02 

7.00E+Ol 7. 84E-03 O.OOE+OO 7.84E-03 

8.00E+Ol 3. 92E-03 O.OOE+OO 3. 92E-OJ 

9.00E+Ol I. 96E-OJ O.OOE+OO 1.96E-03 

1.00E+02 9.81E-04 O.OOE+OO 9.81E-04 

2.00E+02 9. S9E-07 O.OOE+OO 9. 59E-07 

B-543 
INGESTION fl= 1.00E+OO STABLK BROMINE 79 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.29E-03 4.l2E-09 

2.00E-Ol 1.09E-02 2.lOE-OS 

3.00E-Ol 1. 77E-02 4. 92E-OS 

4.00E-Ol 2. 45E-02 S.57E-OS 

5.00E-Ol 3.l3E-Q2 1.2SE-07 

6.00E-Ol 3. 79E-02 1. 73E-07 

7.00E-Ol 4. 46E-02 2.2lE-07 

S.OOE-Ol 5.12E-02 2. 69E-07 

9.00E-Ol 5.77E-02 3.17E-07 

I.OOE+OO 6. 43E-02 6. 43E-Q2 3. 65E-07 3. 65E-07 

2.00E+OO 6. 27E-02 1.27E-OI 3. 59E-07 7. 24E-07 

3.00E+OO 5.S5E-02 I.S5E-Ol 1.6SE-07 S.92E-07 

4.00E+OO 5.45E-02 2.40E-Ol 6. 74E-OS 9.59E-07 

5.00E+OO 5.09E-02 2.9lE-Ol 2. 57E-OS 9.S5E-07 

6.00E+OO 4. 75E-02 3.~SE-Ol O.OOE+OO 9.94E-07 

7.00E+OO 4.43E-02 3.S3E-Ol O.OOE+OO 9.9SE-07 

S.OOE+OO 4.l3E-02 4. 24E-OI O.OOE+OO 9.99E-07 

9.00E+OO 3.S6E-02 4. 62E-Ol O.OOE+OO I.OOE-06 

1.OOE+Ol 3.60E-02 4.9SE-Ol O.OOE+OO 1.OOE-06 

2.00E+Ol 1. SOE-02 7. 49E-Ol O.OOE+OO 1.OOE-06 

3.00E+Ol 9.00E-03 S.75E-Ol O.OOE+OO I.OOE-06 

4.00E+Ol 4.50E-03 9. 37E-Ol O.OOE+OO 1.OOE-06 

5.00E+OI 2.25E-03 9. 69E-OI O.OOE+OO 1.OOE-06 

6.00E+OI 1.l3E-03 9. 84E-Ol O.OOE+OO 1.OOE-06 

7.00E+OI 5. 63E-04 9. 92E-OI O.OOE+OO 1.OOE-06 

S.OOE+Ol 2.SlE-04 9. 96E-Ol O.OOE+OO 1.OOE-06 

9.00E+Ol 1.4lE-04 9.9SE-Ol O.OOE+OO 1.OOE-06 

1.OOE+02 7.04E-05 9.99E-OI O.OOE+OO 1.OOE-06 

2.00E+02 6. SSE-OS I.OOE+OO O.OOE+OO 1.OOE-06 

B-544 
INGESTION f l- I.OO£-tOO BALFLIPE= 1.47£+00 DAYS BROMINE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 8.63E-Ol 8. 65E-02 9.50E-OI 

2.00E-OI 8. 93E-ol 7. 49E-03 9.00E-OI 

3.00E-OI B.52E-0l 6.49E-04 B.53E-Ol 

4.00E-Ol B.OBE-Ol 5.6BE-05 B.OBE-Ol 

5.00E-OI 7.65E-Ol 5. 54E-06 7. 65E-OI 

6.00E-OI 7.25E-Ol 1.04E-06 7. 25E-Ol 

7.00E-Ol 6. 87E-OI 5. 96E-07 6.B7E-Ol 

8.00E-OI 6.5IE-OI 5.04E-07 6.5IE-OI 

9.00E-OI 6.I6E-0l 4. 47E-07 6.16E-OI 

I.OOE+OO 5. 84E-0l 3.97E-07 5.B4E-Ol 

2.00E+OO 3.40E-OI I.08E-07 3.40E-Ol 

3.00E+OO 1.9BE-Ol 2. 63E-OB 1. 98E-Ol 

4.00E+OO 1.I5E-Ol O.OOE+OO 1.15E-Ol 

5.00E+OO 6.71E-02 O.OOE+OO 6.71E-02 

6.00E+OO 3.9lE-02 O.OOE+OO 3.9IE-02 

7.00E+OO 2.2BE-02 O.OOE+OO 2.2BE-02 

8.00E+OO 1. 33E-02 O.OOE+OO 1. 33E-02 

9.00E+OO 7.72E-03 O.OOE+OO 7.72E":"03 

1.OOE+Ol 4. 49E-03 O.OOE+OO 4. 49E-03 

2.00E+Ol 2.0lE-05 O.OOE+OO 2.0lE-05 

3.00E+Ol 9.0IE-08 O.OOE+OO 9.01E-08 

. '.' 

8-545 
INGESTION flm 1.00£+00 BALFLIFE= 1.47£+00 DAYS BROMINE 82 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- -------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4.1OE-03 3. 93E-09 

2.00E-01 9. 95E-03 1.91E-08 

3.00E-01 1. 54E-02 4. 27E-08 

4.00E-01 2.03E-02 7.10E-08 

5.00E-01 2.47E-02 1.01E-07 

6.00E-01 2. 86E-02 1.31E-07 

7.00E-01 3. 21E-02 1. 59E-07 

8.00E-01 3. 51E-02 1.85E-07 

9.00E-01 3. 78E-02 2.08E-07 

1.00E+00 4.01E-02 4.01E-02 2. 27E-07 2.27E-07 

2.00E+00 2. 44E-02 4. 94E-02 1.40E-07 2. 82E-07 

3.00E+00 1. 42E-02 4.50E-02 4.08E-08 2. 17E-07 

4.00E+00 8.27E-03 3. 64E-02 1.02E-08 1.45E-07 

5.00E+00 4. 82E-03 2. 75E-02 O.OOE+OO 9. 32E-08 

6.00E+00 2.80E-03 2.00E-02 O.OOE+OO 5. 87E-08 

7.00E+00 1.63E-03 1. 41E-02 O.OOE+OO 3. 68E-08 

8.00E+00 9.51E-04 9.75E-03 O.OOE+oo 2.30E-08 

9.00E+00 5. 54E-04 6.64E-03 O.OOE+OO 1. 43E-08 

1.00E+01 3. 22E-04 4. 47E-03 O.OOE+OO 8. 96E-09 

2.00E+01 1.44E-06 6.01E-05 O.OOE+OO 8.02E-11 

B-546 
INGESTION f l- 1.00E+OO STABLE RUBIDIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 9.08E-Ol 9.07E-02 9. 99E-Ol 

2.00E-Ol 9. 89E-Ol 8. 23E-03 9. 98E-Ol 

3.00E-Ol 9. 95E-Ol 7.48E-04 9. 96E-Ol 

4.00E-Ol 9.94E-Ol 6. 86E-05 9. 94E-Ol 

5.00E-Ol 9. 93E-Ol 7.02E-06 9. 93E-Ol 

6.00E-Ol 9.91E-Ol 1. 38E-06 9.91E-Ol 

7.00E-Ol 9.90E-Ol 8.30E-07 9.90E-Ol 

8.00E-Ol 9. 88E-Ol 7. 35E-07 9. 88E-Ol 

9.00E-Ol 9.87E-Ol 6. 83E-07 9. 87E-Ol 

1.00E+00 9. 85E-Ol 6. 35E-07 9. 85E-Ol 

2.00E+00 9.70E-Ol 2. 76E-07 9.70E-Ol 

3.00E+00 9. 54E-Ol 1.08E-07 9. 54E-Ol 

4.00E+00 9.40E-Ol 4.09E-08 9.40E-Ol 

5.00E+00 9. 25E-Ol 1. 52E-08 9. 25E-Ol 

6.00E+00 9.IOE-Ol O.OOE+OO 9.IOE-Ol 

7.00E+00 8. 96E-Ol O.OOE+OO 8. 96E-Ol 

8.00E+00 8. 82E-01 O.OOE+OO 8. 82E-Ol 

9.00E+00 8. 68E-Ol O.OOE+OO 8. 68E-Ol 

1.00E+Ol 8. 55E-Ol O.OOE+OO 8. 55E-Ol 

2.00E+Ol 7.30E-Ol O.OOE+OO 7.30E-Ol 

3.00E+Ol 6. 24E-Ol O.OOE+OO 6. 24E-Ol 

4.00E+Ol 5. 33E-Ol O.OOE+OO 5. 33E-Ol 

5.00E+Ol 4. 55E-Ol O.OOE+OO 4. 55E-Ol 

6.00E+Ol 3. 89E-Ol O.OOE+OO 3. 89E-Ol 

7.00E+Ol 3. 32E-Ol O.OOE+OO 3. 32E-Ol 

8.00E+Ol 2. 84E-Ol O.OOE+OO 2. 84E-Ol 

9.00E+Ol 2.42E-Ol O.OOE+OO 2. 42E-Ol 

1.00E+02 2.07E-Ol O.OOE+OO 2.07E-Ol 

2.00E+02 4.29E-02 O.OOE+OO 4. 29E-02 

3.00E+02 8. 88E-03 O.OOE+OO 8. 88E-03 

4.00E+02 1.84E-03 O.OOE+OO 1. 84E-03 

5.00E+02 3.80E-04 O.OOE+OO 3.80E-04 

6.00E+02 7. 87E-05 O.OOE+OO 7. 87E-05 

7.00E+02 1. 63E-05 O.OOE+OO 1. 63E-05 

8.00E+02 3 •. 37E-06 O.OOE+OO 3. 37E-06 

9.00E+02 6. 98E-07 O.OOE+OO 6. 98E-07 

.. 1.00E+03 1.45E-07 O.OOE+OO 1. 45E-07 

B-547 
INGESTION f 1- l.ooE+OO S'lABU RUBmIUH 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.00E-0l 7. 33E-04 2. 44E-04 

2.00E-OI I. 87E-03 6. 24E-04 

3.00E-Ol 3.05E-03 1.02E-03 

4.00E-Ol 4. 22E-03 1.4lE-03 

5.00E-Ol 5. 39E-03 1.80E-03 

6.00E-Ol 6. 57E-03 2. 19E-03 

7.00E-Ol 7. 74E-03 2. 58E-03 

8.00E-Ol 8.90E-03 2. 97E-03 

9.00E-Ol 1.0IE-02 3. 36E-03 

1.00E+OO 1. 12E-02 1.12E-02 3. 75E-03 3.7SE-03 

2.00E+OO 1.ISE-02 2. 28E-02 3.8SE-03 7.S9E-03 

3.00E+OO 1.14E-02 3. 41E-02 3. 79E-03 1.i4E-02 

4.00E+OO 1.12E-02 4. 53E-02 3.73E-03 1.5lE-02 

5.00E+OO l.lOE-02 5. 63E-02 3. 67E-03 1. 88E-02 

6.00E+OO I.08E-02 6. 72E-02 3.6lE-03 2. 24E-02 

7.00E+OO 1.07E-02 7. 79E-02 3. 56E-03 2.60E-02 

8.00E+OO 1.05E-02 B.84E-02 3.50E-03 2.9SE-02 

9.00E+OO 1.03E-02 9.B7E-02 3. 45E-03 3. 29E-02 

1.00E+Ol I.02E-02 1.09E-0l 3. 39E-03 3. 63E-02 

2.00E+Ol B.69E-03 2.02E-Ol 2.90E-03 6. 74E-02 

3.00E+Ol 7. 43E-03 2. 82E-OI 2. 48E-03 9.40E-02 

4.00E+Ol 6. 35E-03 3.50E-Ol 2.l2E-03 1.l7E-OI 

S.OOE+Ol 5. 42E-03 4.09E-Ol 1.8lE-03 1.36E-Ol 

6.00E+Ol 4. 63E-03 4.5BE-Ol 1. 54E-03 1. 53E-Ol 

7.00E+Ol 3. 96E-03 5.0lE-Ol 1.32E-03 1. 67E-Ol 

8.00E+OI 3.3BE-03 5. 37E-Ol 1.13E-03 1. 79E-Ol 

9.00E+Ol 2. 89E-03 5. 68E-Ol 9.62E-04 1. 89E-Ol 

1.OOE+02 2. 47E-03 5. 95E-Ol 8. 22E-04 1. 98E-Ol 

2.00E+02 5.11E-04 7. 18E-Ol 1.70E-04 2. 39E-Ol 

3.00E+02 1.06E-04 7.43E-Ol 3. 52E-05 2. 48E-Ol 

4.00E+02 2. 19E-05 7.49E-Ol 7.29E-06 2.50E-Ol 

5.00E+02 4. 53E-06 7.50E-Ol 1. 51E-06 2.50E-Ol 

6.00E+02 9. 37E-07 7.50E-OI 3. 12E-07 2.50E-Ol 

7.00E+02 1. 94E-07 7.50E-Ol 6.47E-OB 2.50E-Ol 

B.OOE+02 4.02E-OB 7.50E-OI 1.34E-OB 2.50E-Ol 

B-548 
INGESTION f l- 3.00E-ol IlALFLIPE= 6.48E+Ol DAYS STRONTIUM 85 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEHIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 1.07E-01 8.81E-01 9. 89E-01 

2.00E-01 1.90E-01 7. 76E-01 9. 66E-01 

3.00E-01 2. 26E-01 7. 16E-01 9.42E-01 

4.00E-01 2. 39E-01 6. 77E-01 9. 16E-01 

5.00E-01 2. 42E-01 6.44E-01 8. 86E-01 

6.00E-01 2. 41E-01 6. 12E-01 8. 53E-01 

7.00E-01 2.38E-01 5. 79E-01 8. 18E-01 

8.00E-01 2. 35E-01 5. 46E-01 7.81E-01 

9.00E-01 2. 32E-01 5. 12E-01 7. 44E-01 

1.00E+00 2. 29E-01 4. 78E-01 7.07E-01 

2.00E+00 1.98E-01 2. 11E-01 4. fOE-01 

3.00E+00 1. 74E-01 8. 26E-02 2. 57E-01 

4.00E+00 1.55E-01 3.10E-02 1. 86E-01 

5.00E+00 1. 38E-01 1. 14E-02 1.50E-01 

6.00E+QO 1. 25E-01 4. 18E-03 1.29E-01 

7.00E+00 1. 14E-01 1. 52E-03 1. 15E-01 

8.00E+00 1.04E-01 5. 55E-04 1.05E-01 

9.00E+00 9. 59E-02 2.02E-04 9.61E-02 

1.00E+01 8. 89E-02 7. 36E-05 8.90E-02 

2.aOE+01 5. 48E-02 O.OOE+OO 5. 48E-02 

3.00E+01 4. 39E-02 O.OOE+OO 4. 39E-02 

4.00E+01 3. 78E-02 O.OOE+OO 3. 78E-02 

5.00E+01 3. 31E-02 O.OOE+OO 3.31E-02 

6.00E+01 2. 91E-02 O.OOE+OO 2.91E-02 

7.00E+01 2. 57E-02 O.OOE+OO 2. 57E-02 

8.00E+01 2. 26E-02 O.OOE+OO 2. 26E-02 

9.00E+01 2.00E-02 O.OOE+OO 2.00E-02 

1.00E+02 1.77E-02 O.OOE+OO 1.77E-02 

2.00E+02 5.30E-03 O.OOE+OO 5.30E-03 

3.00E+02 1. 65E-03 O.OOE+OO 1. 65E-03 

4.00E+02 5. 26E-04 O.OOE+OO 5. 26E-04 

5.00E+02 1.70E-04 O.OOE+OO 1.70E-04 

6.00E+02 5. 55E-05 O.OOE+OO 5.55E-05 

7.00E+02 1. 83E-05 O.OOE+OO 1. 83E-05 

8.00E+02 6.04E-06 O.OOE+OO 6.04E-06 

9.00E+02 2.01E-06 O.OOE+OO 2.01E-06 .-./" " 1.00E+03 6.68E-07 O.OOE+OO 6.68E-07 

B-549 
INGESTION fl= 3.00E-ol HALFLIFE- 6.48E+Ol DAYS STRONTIUtI 8S 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-1I0UR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 8. 15E-03 2.02E-03 

2.00E-Ol 2. 24E-02 9.31E-03 

3.00E-Ol 3. 22E-02 2. 25E-02 

4.00E-Ol 3. 84E-02 4. 18E-02 

5.00E-Ol 4. 28E-02 6. 62E-02 

6.00E-Ol 4. 63E-02 9. 45E-02 

7.00E-Ol 4. 95E-02 1.26E-Ol 

8.00E-Ol 5. 24E-02 1. 58E-Ol 

9.00E-Ol 5. 52E-02 1.91E-Ol 

1.00E+00 5. 79E-02 5. 79E-02 2. 24E-Ol 2. 24E-Ol 

2.00E+00 2. 37E-02 8.10E-02 2. 66E-Ol 4. 88E-Ol 

3.00E+00 1.87E-02 9. 89E-02 1.30E-Ol 6. 13E-01 

4.00E+00 1.51E-02 1. 13E-01 5.34E-02 6.60E-Ol 

5.00E+00 1. 24E-02 1. 24E-01 2. 14E-02 6. 74E-01 

6.00E+00 1.02E-02 1. 33E-01 8. 92E-03 6. 76E-Ol 

7.00E+00 8.50E-03 1.40E-Ol 4. 11E-03 6. 73E-Ol 

8.00E+00 7.11E-03 1.46E-01 2. 21E-03 6. 68E-Ol 

9.00E+00 5. 98E-03 1.50E-01 1.40E-03 6. 62E-01 

1.00E+Ol 5.04E-03 1. 54E-Ol 1.02E-03 6. 56E-01 

2.00E+Ol 9. 94E-04 1.59E-Ol 1. 75E-04 5.93E~01 

3.00E+01 2. 48E-04 1. 48E-01 4. 38E-05 5.34E-U1 

4.00E+Ol 1.01E-04 1. 34E-Ol 1. 77E-05 4.80E-01 

5.00E+Ol 6. 44E-05 1.21E-Ol 1. 14E-05 4. 32E-01 

6.00E+Ol 5.03E-05 1.10E-Ol 8. 88E-06 3. 88E-Ol 

7.00E+Ol 4.15E~05 9. 88E-02 7.33E-06 3. 49E-Ol 

8.00E+Ol 3. 48E-05 8. 92E-02 6. 14E-06 3. 13E-Ol 

9.00E+Ol 2. 93E-05 8.04E-02 5. 17E-06 2. 82E-Ol 

1.00E+02 2.47E-05 7.25E-02 4.36E-06 2. 53E-Ol 

2.00E+02 5.03E-06 2. 56E-02 8. 88E-07 8.70E-02 

3.00E+02 1. 18E-06 8. 92E-03 2.08E-07 2. 99E-02 

4.00E+02 3.00E-07 3.10E-03 5.30E-08 1.03E-02 

5.00E+02 8.00E-08 1.07E-03 1.41E-08 3. 53E-03 

6.00E+02 2.20E-08 3.71E-04 O.OOE+OO 1.21E-03 

B-550 
INGESTION f 1'''' 3.00E~1 STABLE STRONTIUK 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI I.07E-0l 8. 82E-OI 9.90E-OI 

2.00E-OI 1.9IE-OI 7. 77E-OI 9. 68E-OI 

3.00E-OI 2. 26E-OI 7 .. 19E-OI 9. 45E-OI 

4.00E-OI 2.40E-OI 6.80E-OI 9.19E-OI 

5.00E-OI 2. 43E-OI 6.47E-OI 8.90E-OI 

6.00E-OI 2.42E-OI 6.16E-OI 8. 58E-OI 

7.00E-OI 2.40E-OI 5. 83E-OI 8. 24E-OI 

8.00E-OI 2. 37E-OI 5.50E-OI 7. 88E-OI 

9.00E-OI 2. 34E-OI 5. 17E-OI 7.5IE-OI 

I.OOE+OO 2.3IE-OI 4. 84E-OI 7.15E-OI 

2.00E+OO 2.03E-OI 2.16E-OI 4.18E-OI 

3.00E+OO 1.80E-OI 8. 53E-02 2. 65E-OI 

4.00E+OO I.6IE-OI 3. 23E-02 I.94E-OI 

5.00E+OO 1. 46E-OI I.20E-02 1. 58E-OI 

6.00E+OO 1.33E-OI 4. 45E-03 1. 38E-OI 

7.00E+OO 1. 22E-OI 1.64E-03 1. 24E-OI 

8.00E+OO 1. 13E-OI 6.05E-04 1.14E-0l 

9.00E+OO I.06E-OI 2. 23E-04 I.06E-OI 

I.OOE+OI 9.90E-02 8.19E-05 9.9IE-02 

2.00E+OI 6. 79E-02 O.OOE+OO 6. 79E-02 

3.00E+OI 6.05E-02 O.OOE+OO 6.05E-02 

4.00E+OI 5.80E-02 O.OOE+OO 5.80E-02 

5.00E+OI 5. 65E-02 O.OOE+OO 5.65E-02 

6.00E+OI 5. 53E-02 O.OOE+OO 5. 53E-02 

7.00E+OI 5. 42E-02 O.OOE+OO 5.42E-02 

8.00E+OI 5. 32E-02 O.OOE+OO 5. 32E-02 

9.00E+0l 5.23E-02 O.OOE+OO 5. 23E-02 

I.OOE+02 5.14E-02 O.OOE+OO 5.I4E-02 

2.00E+02 4.50E-02 O.OOE+OO 4.50E-02 

3.00E+02 4.08E-02 O.OOE+OO 4.08E-02 

4.00E+02 3. 79E-02 O.OOE+OO 3. 79E-02 

5.00E+02 3. 56E-02 O.OOE+OO 3. 56E-02 

6.00E+02 3. 39E-02 O.OOE+OO 3.39E-02 

7.00E+02 3.24E-02 O.OOE+OO 3.24E-02 

8.00E+02 3.I3E-02 O.OOE+OO 3. 13E-02 

9.00E+02 3.02E-02 O.OOE+OO 3.02E-02 

I.OOE+03 2. 94E-02 O.OOE+OO 2. 94E-02 

2.00E+03 2. 36E-02 O.OOE+OO 2. 36E-02 

3.00E+03 1. 97E-02 O.OOE+OO 1. 97E-02 

4.00E+03 1.68E-02 O.OOE+OO 1.68E-02 

5.00E+03 I.46E-02 O.OOE+OO I.46E-02 

7.00E+03 1.13E-02 O.OOE+OO· I.I3E-02 

8.00E+03 I.OlE-02 O.OOE+OO 1.0lE-02 

9.00E+03 9.08E-03 O.OOE+OO 9.08E-03 

I.OOE+04 8.2IE-03 O.OOE+OO 8.2IE-03 

2.00E+04 3. 36E-03 O.OOE+OO 3. 36E-03 

B-551 
INGESTION £1= 3.00K-ol STABLE STRONTIUM 88 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------~---------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATE 

DAYS URINE URINE FECES FECES 

1.00E-Ol B.lSE-03 2.02E-03 

2.00E-Ol 2.2SE-02 9.33E-03 

3.00E-Ol 3.23E-02 2.26E-02 

4.00E-Ol 3. BSE-02 4.20E-02 

S.OOE-Ol 4.30E-02 6.66E-02 

6.00E-Ol 4. 66E-02 9.S2E-02 

7.00E-Ol 4.9BE-02 1.26E-01 

B.OOE-Ol S.2BE-02 1.S9E-01 

9.00E-Ol S. S7E-02 1.93E-0l 

1.00E+00 S.BSE-02 S.BSE-02 2.27E-Ol 2.27E-Ol 

2.00E+00 2.43E-02 8.27E-02 2.72E-Ol 4. 99E-Ol 

3.00E+OO 1. 94E-02 1.02E-01 1.34E-01 6.33E-Ol 

4.00E+00 1.SBE-02 1.lBE-0l S. SBE-02 6.BBE-Ol 

S.OOE+OO 1.30E-02 1.3lE-01 2. 26E-02 7.11E-Ol 

6.00E+00 1.09E-02 1.42E-01 9. SlE-03 7.2lE-0l 

7.00E+00 9.l6E-03 1.SlE-01 4. 43E-03 7.2SE-Ol 

B.OOE+OO 7.7SE-03 1. S9E-Ol 2.4lE-03 7.27E-Ol 

9.00E+00 6.SBE-03 1.6SE-01 1. S4E-03 7.29E-Ol 

1.00E+Ol S.6lE-03 1.71E-01 1.13E-03 7.30E-Ol 

2.00E+Ol 1. 23E-03 1.97E-01 2.l7E-04 7.3SE-Ol 

3.00E+Ol 3.42E-04 2.04E-Ol 6.03E-OS 7.36E-Ol 

4.00E+Ol 1. S4E-04 2.06E-Ol 2.72E-OS 7.36E-Ol 

S.OOE+Ol 1.10E-04 2.07E-Ol 1.94E-OS 7.37E-Ol 

6.00E+Ol 9.S6E-OS 2.0BE-Ol 1.69E-OS 7.37E-Ol 

7.00E+Ol B.7BE-OS 2.09E-Ol 1. SSE-OS 7.37E-Ol 

8.00E+Ol B.18E-OS 2.lOE-01 1.44E-OS 7.37E-Ol 

9.00E+Ol 7. 66E-OS 2. llE-Ol 1.3SE-OS 7.37E-Ol 

1.00E+02 7.20E-OS 2.llE-01 1.27E-OS 7.37E-Ol 

2.00E+02 4.27E-OS 2.l7E-01 7. S3E-06 7. 38E-Ol 

3.00E+02 2. 92E-OS 2.20E-Ol S.lSE-06 7.39E-Ol 

4.00E+02 2.l6E-OS 2.23E-Ol 3. BlE-06 7.39E-Ol 

S.00E+02 1.6BE-OS 2.2SE-Ol 2. 96E-06 7.40E-Ol 

6.00E+02 1.34E-OS 2. 26E-Ol 2.37E-06 7.40E-Ol 

7.00E+02 1.lOE-OS 2.27E-Ol 1.9SE-06 7.40E-Ol 

8.00E+02 9.3lE-06 2.2BE-Ol 1.64E-06 7.40E-Ol 

9.00E+02 B.02E-06 2. 29E-Ol 1.4lE-06 7.40E-Ol 

1.00E+03 7.0SE-06 2.30E-Ol 1. 24E-06 7.4lE-01 

2.00E+03 3. 79E-06 2.3SE-Ol 6.6BE-07 7.4lE-01 

3.00E+03 2.BlE-06 2.3BE-Ol 4.96E-07 7. 42E-Ol 

4.00E+03 2.l7E-06 2.4lE-01 3.B3E-07 7.42E-Ol 

S.00E+03 1.71E':"06 . 2.43E-Ol 3.0lE-07 7. 43E-Ol 

7.00E+03 1.13E-06 2.4SE-Ol 1. 99E-07 7. 43E-Ol 

B.OOE+03 9.4lE-07 2.46E-Ol 1.66E-07 7. 43E-Ol 

9.'OOE+03 B.OOE-07 2.47E-Ol 1.4lE-07 7.44E-Ol 

1.OOE+04 6.9lE-07 2.4BE-Ol 1. 22E-07 7. 44E-OI 

2,.OOE+04 2. 43E-07 2. S2E-Ol 4.30E-OB 7.44E-Ol 

B-SS2 
INGESTION f 1- 3.00£-01 BALFLlFE- 1.06E+o4 DAYS STRONTIUK 90 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------------~--

SYSTEMIC GI TOTAL 

DAYS ORGANS . TRACT BODY 

1.00E-01 1.07E-01 8. 82E-Ol 9.90E-Ol 

2.00E-01 1.91E-Ol 7. 77E-Ol 9. 68E-Ol 

3.00E-Ol 2. 26E-Ol 7. 19E-Ol 9.45E-Ol 

4.00E-Ol 2.40E-Ol 6.80E-Ol 9. 19E-Ol 

5.00E-Ol 2. 43E-Ol 6.47E-Ol 8.90E-Ol 

6.00E-Ol 2. 42E-Ol 6. 16E-Ol 8. 58E-Ol 

7.00E-01 2.40E-01 5. 83E-Ol 8. 24E-Ol 

8.00E-01 2. 37E-Ol 5.50E-Ol 7.88E-Ol 

9.00E-Ol 2.34E-01 5.17E-01 7.51E-01 

1.00E+00 2.31E-Ol 4. 83E-Ol 7.15E-Ol 

2.00E+00 2.03E-01 2. 16E-Ol 4. 18E-01 

3.00E+00 1.80E-Ol 8. 53E-02 2. 65E-Ol 

4.00E+00 1.61E-Ol 3. 23E-02 1. 94E-Ol 

5.00E+00 1.46E-Ol 1.20E-02 1. 58E-Ol 

6.00E+00 1 • .33E-Ol 4. 45E-03 1.38E-Ol 

7.00E+00 1.22E-Ol 1.64E-03 1. 24E-Ol 

8.00E+00 1. 13E-01 6.04E-04 1. 14E-01 

9.00E+00 1.06E-Ol 2. 22E-04 1.06E-Ol 

1.00E+Ol 9. 89E-02 8. 18E-05 9.90E-02 

2.00E+Ol 6. 78E-02 O.OOE+OO 6. 78E-02 

3.00E+Ol 6.04E-02 O.OOE+OO 6.04E-02 

4.00E+Ol 5. 78E-02 O.OOE+OO 5. 78E-02 

5.00E+Ol 5. 63E-02 O.OOE+OO 5. 63E-02 

6.00E+Ol 5.51E-02 O.OOE+OO 5. 51E-02 

7.00E+Ol 5.40E-02 O.OOE+OO 5.40E-02 

8.00E+Ol 5.30E-02 O.OOE+OO 5.30E-02 

9.00E+Ol 5.20E-02 O.OOE+OO 5.20E-02 

1.00E+02 5. 11E-02 O.OOE+OO 5. 11E-02 

2.00E+02 4. 44E-02 O.OOE+OO 4. 44E-02 

3.00E+02 4.00E-02 O.OOE+OO 4.00E-02 

4.00E+02 3. 69E-02 O.OOE+OO 3. 69E-02 

5.00E+02 3. 45E-02 O.OOE+OO 3.45E-02 

6.00E+02 3. 26E-02 O.OOE+OO 3. 26E-02 

7.00E+02 3.10E-02 O.OOE+OO 3.10E-02 

8.00E+02 2 •. 97E-02 O.OOE+OO 2. 97E-02 

9.00E+02 2. 85E-02 O.OOE+OO 2. 85E-02 

1.00E+03 2. 75E-02 O.OOE+OO 2.75E-02 

2.00E+03 2.07E-02 O.OOE+OO 2.07E-02 

3.00E+03 1. 62E-02 O.OOE+OO 1. 62E-02 

4.00E+03 1.30E-02 O.OOE+OO 1.30E-02 

5.00E+03 1.05E-02 O.OOE+OO 1.05E-02 

7.00E+03 7. 16E-03 O.OOE+OO 7. 16E-03 

8.00E+03 5. 99E-03 O.OOE+OO 5. 99E-03 

9.00E+03 5.04E-03 O.OOE+OO 5.04E-03 

1.00E+04 4. 27E-03 O.OOE+OO 4. 27E-03 

2.00E+04 9.09E-04 O.OOE+OO 9.09E-04 

B-553 
INGESTION fl= 3.00E-ol HALFLIFE- 1.06E+04 DAYS STROIf,l'IUH 90 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR ACCUMULA 

DAYS URINE URINE FECES FECES 

1.00E-01 8. 15E-03 2.02E-03 

2.00E-01 2. 25E-02 9. 33E-03 

3.00E-01 3. 23E-02 2. 26E-02 

4.00E-01 3. 85E-02 4.20E-02 

5.00E-01 4.30E-02 6. 66E-02 

6. OOE-O 1 4. 66E-02 9.51E-02 

7.00E-01 4. 98E-02 1.26E-01 

8.00E-01 5. 28E-02 1a59E-01 

9.00E-Ol 5. 57E-02 1. 93E-Ol 

1.00E+00 5. 85E-02 5.85E-02 2. 27E-Ol 2.27E-01 

2.00E+00 2.42E-02 8. 27E-02 2.72E-Ol 4. 99E-Ol 

3.00E+00 1. 94E-02 1.02E-Ol 1. 34E-Ol 6. 33E-Ol 

4.00E+00 1. 58E-02 1. 18E-Ol 5.58E-02 6. 88E-01 

5.00E+00 1.30E-02 1.31E-01 2. 26E-02 7. 11E-01 

6.00E+00 1.09E-02 1.42E-Ol 9.51E-03 7.20E-Ol 

7.00E+00 9. 15E-03 1. 51E-Ol 4. 43E-03 7. 25E-Ol 

8.00E+00 7. 74E-03 1. 59E-Ol 2.40E-03 7.27E-Ol 

9.00E+00 6. 58E-03 1. 65E-Ol 1. 54E-03 7.29E-Ol 

1.00E+Ol 5.60E-03 1.71E-Ol 1. 13E-03 7.30E-Ol 

2.00E+Ol 1. 23E-03 1.97E-01 2. 17E-04 7. 34E-Ol 

3.00E+Ol 3.41E-04 2.03E-Ol 6.02E-05 7.34E-Ol 

4.00E+Ol 1. 54E-04 2.05E-Ol 2. 71E-05 7. 34E-Ol 

5.00E+01 1.10E-04 2.06E-Ol 1.93E-05 7. 34E-Ol 

6.00E+Ol 9. 52E-05 2.07E-Ol 1. 68E-05 7. 34E-Ol 

7.00E+Ol 8. 74E-05 2.08E-Ol 1.54E-05 7.34E-Ol 

8.00E+Ol 8. 14E-05 2.09E-Ol 1. 44E-05 7.33E-Ol 

9.00E+Ol 7.62E-05 2.09E-Ol 1. 34E-05 7.33E-Ol 

1.00E+02 7. 15E-05 2.IOE-Ol 1. 26E-05 7. 32E-Ol 

2.00E+02 4.21E-05 2. 14E-Ol 7.44E-06 7.29E-Ol 

3.00E+02 2. 86E-05 2. 16E-Ol 5.05E-06 7. 25E-Ol 

4.00E+02 2.IOE-05 2. 17E-Ol 3. 71E-06 7.20E-Ol 

5.00E+02 1. 62E-05 2. 17E-Ol 2. 86E-06 7. 16E-Ol 

6.00E+02 1. 29E-05 2. 17E-01 2. 28E-06 7.11E-Ol 

7.00E+02 1.06E-05 2. 17E-01 1. 86E-06 7.07E-Ol 

8.00E+02 8. 83E-06 2. 17E-Ol 1.56E-06 7.03E-Ol 

9.00E+02 7. 56E-06 2. 16E-Ol 1. 33E-06 6.98E-Ol 

1.00E+03 6. 61E-06 2. 15E-Ol 1. 17E-06 6. 94E-Ol 

2.00E+03 3. 32E-06 2.06E-Ol 5. 86E-07 6.51E-Ol 

3.00E+03 2.31E-06 1.96E-Ol 4.08E-07 6.IOE-01 

4.00E+03 1. 67E-06 1.85E-Ol 2. 95E-07 5. 72E-Ol 

5.00E+03 1. 23E-06 1. 75E-Ol 2. 17E-07 5. 36E-Ol 

7.00E+03 7. 12E-07 1. 55E-Ol 1. 26E-07 4.70E-Ol 

8.00E+03 5. 58E-07 1.46E-Ol 9. 84E-08 4.41E-01 

9.00E+03 4. 44E-07 1.37E-Ol 7. 84E-08 4. 13E-Ol 

1.00E+04 3. 59E-07 1.29E-Ol 6. 34E-08 3. 87E-Ol 

2.00E+04 6. 58E-08 6. 82E-02 1. 16E-08 2.01E-Ol 

B-554 
INGESTIOB fim I .. OOE-Q4 BALFLIFE- 5.85E+OI DAYS nTRIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2.90E-OS 9.9BE-OI 9.9BE-Ol 

2.00E-OI S.66E-OS 9. 92E-OI 9.92E-OI 

3.00E-Ol 7.09E-OS 9.77E-OI 9.77E-OI 

4.00E-OI 7. 73E-OS 9. 54E-OI 9.S4E-OI 

S.OOE-OI 7. 96E-05 9.23E-OI 9. 23E-OI 

6.00E-OI B.OOE-OS B.BSE-Ol B.BSE-Ol 

7.00E-Ol 7.9SE-OS B.43E-OI B.44E-0l 

B.OOE-OI 7.B6E-OS 7. 99E-OI 7. 99E-OI 

9.00E-OI 7. 78E-OS 7. S2E-Ol 7.S2E-OI 

I.OOE+OO 7.70E-OS 7.0SE-OI 7.05E-OI 

2.00E+OO 7. 34E-OS 3.16E-OI 3.l6E-OI 

3.00E+OO 7. 24E-05 1. 24E-OI 1. 24E-OI 

4.00E+OO 7.15E-05 4. 66E-02 4. 67E-02 

5.00E+OO 7.07E-OS 1.72E-02 1.72E-02 

6.00E+OO 6. 99E-05 6.2BE-03 6. 35E-03 

7.00E+OO 6.90E-OS 2. 29E-03 2. 36E-03 

B.OOE+OO 6.B2E-05 B.33E-04 9.0IE-04 

9.00E+OO 6. 74E-05 3.03E-04 3.70E-04 

I.OOE+OI 6. 66E-05 I.lOE-04 I.77E-04 

2.00E+OI 5. 92E-OS O.OOE+OO S.92E-05 

3.00E+OI 5. 26E-05 O.OOE+OO S.26E-05 

4.00E+OI 4. 67E-OS O.OOE+OO 4. 67E-05 

5.00E+OI 4. ISE-OS O.OOE+OO 4. ISE-OS 

6.00E+OI 3.6BE-OS O.OOE+OO 3.6BE-OS 

7.00E+OI 3. 27E-05 O.OOE+OO 3. 27E-OS 

B.OOE+OI 2.9IE-OS O.OOE+OO 2.9IE-05 

9.00E+OI 2.5BE-05 O.OOE+OO 2.5BE-05 

I.OOE+02 2. 29E-OS O.OOE+OO 2. 29E-05 

2.00E+02 7.02E-06 O.OOE+OO 7.02E-06 

3.00E+02 2. ISE-06 O.OOE+OO 2.15E-06 

4.00E+02 6.56E-07 O.OOE+OO 6. 56E-07 

5.00E+02 2.0IE-07 O.OOE+OO 2.0IE-07 

6.00E+02 6.14E-OB O.OOE+OO 6.14E-OB 

7.00E+02 I.BBE-OB O.OOE+OO I.BBE-OB 

. , 

B-55S 
INGESnOli f 1'= 1.00E-04 BAL:FLIFE- 5.85E+Ol DAYS Y'lTRIOM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 7. 92E-07 6.09E-04 

2.00E-Ol 3. 42E-06 S.89E-03 

3.00E-Ol 6.83E-06 1. 93E-02 

4.00E-Ol 1.02E-OS 4.l4E-02 

S.OOE-Ol 1. 32E-OS 7.13E-02 

6.00E-Ol 1.S7E-OS 1.07E-Ol 

7.00E-0l 1.77E-OS 1. 48E-Ol 

8.00E-Ol 1. 93E-OS 1. 92E-Ol 

9.00E-0l 2.06E-OS 2.37E-Ol 

1.OOE+OO 2.lSE-QS 2.lSE-OS 2. 83E-Ol 2. 83E-Ol 

2.00E+OO 2. 94E-06 2. 42E-OS 3.8lE-0l 6.60E-Ol 

3.00E+OO 1.86E-07 2.4lE-OS 1.88E-0l 8.4lE-Ol 

4.00E+OO 1.lsE-08 2. 38E-Os 7. 62E-02 9.07E-Ol 

B-ss6 
INGESTION f 1''''' 2.00£-03 STABLE ZIRCONIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5.97E-04 9.99E-01 9.99E-01 

2.00E-01 1.20E-03 9.93E-01 9.94E-01 

3.00E-01 1.55E-03 9.79E-01 9.81E-01 

4.00E-01 1.74E-03 9.57E-01 9.58E-01 

5.00E-01 1.84E-03 9.26E-01 9.28E-01 

6.00E-01 1.89E-03 8.90E-01 8.92E-01 

7.00E-01 1.91E-03 8.49E-01 8.51E-Ol 

8.00E-01 1.92E-03 8.05E-01 8.06E-01 

9.00E-01 1.92E-03 7.59E-Ol 7.60E-01 

1.00E+00 1.92E-03 7.12E-01 7.14E-01 

2.00E+00 1.84E-03 3.23E-01 3.25E-01 

3.00E+00 1.76E-03 1.28E-Ol 1.30E-01 

4.00E+00 1.69E-03 4.88E-02 5.05E-02 

5.00E+00 1.62E-03 1.82E-02 1.98E-02 

6.00E+00 1.56E-03 6.73E-03 8.29E-03 

7.00E+OO 1.51E-03 2.48E-03 3.99E-03 

8.00E+00 1.46E-03 9.14E-04 2.38E-03 

9.00E+00 1.42E-03 3.36E-04 1.75E-03 

1.00E+Ol 1.38E-03 1.24E-04 1. 50E-03 

2.00E+Ol 1.14E-03 O.OOE+OO 1.14E-03 

3.00E+01 1.05E-03 O.OOE+OO 1.05E-03 

4.00E+01 1.02E-03 O.OOE+OO 1.02E-03 

5.00E+01 1.00E-03 O.OOE+OO 1.00E-03 

6.00E+01 9.98E-04 O.OOE+OO 9.98E-04 

7.00E+Ol 9.95E-04 O.OOE+OO 9.95E-04 

8.00E+01 9.93E-04 O.OOE+OO 9.93E-04 

9.00E+Ol 9.92E-04 O.OOE+OO 9.92E-04 

1.00E+02 9.91E-04 O.OOE+OO 9.91E-04 

2.00E+02 9.83E-04 O.OOE+OO 9.83E-04 

3.00E+02 9.74E-04 O.OOE+OO 9.74E-04 

4.00E+02 9.66E-04 O.OOE+OO 9.66E-04 

5.00E+02 9.58E-04 O.OOE+OO 9.58E-04 

6.00E+02 9.49E-04 O.OOE+OO 9.49E-04 

7.00E+02 9.41E-04 O.OOE+OO 9.41E-04 

8.00E+02 9 •. 33E-04 O.OOE+OO 9.33E-04 

9.00E+02 9.25E-04 O.OOE+OO 9.25E-04 .. ' 1.00E+03 9.17E-04 O.OOE+OO 9.17E-04 

2.00E+03 8.41E-04 O.OOE+OO 8.41E-04 

3.00E+03 7.71E-04 O.OOE+OO 7.71E-04 

4.00E+03 7.07E-04 O.OOE+OO 7.07E-04 

5.00E+03 6.48E-04 O.OOE+OO 6.48E-04 

7.00E+03 5.45E-04 O.OOE+OO 5.45E-04 

8.00E+03 5.00E-04 O.OOE+OO 5.00E-04 

9.00E+03 4.59E-04 O.OOE+OO 4.59E-04 

1.00E+04 4.21E-04 O.OOE+OO 4.21E-04 

2.00E+04 1.77E-04 O.OOE+OO 1.77E-04 

B-557 
INGESTION £1= 2.00E-03 STABLE ZIRCONIUM 91 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-Ol l.22E-06 6.09E-04 

2.00E-Ol 5.77E-06 5.90E-03 

3.00E-Ol l.26E-05 l.93E-02 

4.00E-Ol 2.07E-05 4.l6E-02 

5.00E-OI 2.95E-05 7.l7E-02 

6.00E-Ol 3.86E-05 L08E-Ol 

7.00E-Ol 4.78E-05 l.49E-Ol 

8.00E-Ol 5.70E-05 l.93E-Ol 

9.00E-Ol 6.62E-05 2.39E-Ol 

I.OOE+OO 7.54E-OS 7.54E-05 2.B6E-Ol 2.B6E-Ol 

2.00E+OO B.72E-05 l.63E-04 3.89E-Ol 6.75E-Ol 

3.00E+OO 7.90E-05 2.42E-04 l.94E-Ol B.70E-OI 

4.00E+OO 7.16E-05 3.13E-04 7.97E-02 9.49E-OI 

5.00E+OO 6.49E-05 3.78E-04 3.06E-02 9.BOE-OI 

6.00E+OO 5.B7E-05 4.37E-04 1.15E-02 9.9IE-OI 

7.00E+OO 5.32E-OS 4.90E-04 4.25E-03 9.96E-OI 

8.00E+OO 4.B2E-OS 5.3BE-04 1.57E-03 9.97E-OI 

9.00E+OO 4.37E-05 5.82E-04 5. 77E-04 9.98E-OI 

l.OOE+OI 3.96E-05 6.21E-04 2.13E,-04 9.98E-OI 

2.00E+Ol 1.4BE-05 8.6IE-04 O.OOE+OO 9.98E-OI 

3.00E+OI 5.54E-06 9.50E-04 O.OOE+OO 9.9BE-OI 

4.00E+OI 2.11E-06 9.84E-04 O.OOE+OO 9.98E-OI 

5.00E+Ol B.39E-07 9.97E-04 O.OOE+OO 9.98E-OI 

7.00E+OI 1.90E-07 I.OIE-03 O.OOE+OO 9.98E-OI 

B.OOE+OI 1.25E-07 I.OIE-03 O.OOE+OO 9.98E"':OI 

9.00E+OI I.OOE-07 I.OIE-03 O.OOE+OO 9.98E-OI 

I.OOE+02 9.12E-08 I.OIE-03 O.OOE+OO 9.98E-OI 

2.00E+02 8.5IE-08 I.02E-03 O.OOE+OO 9.98E-OI 

3.00E+02 8.44E-08 L03E-03 O.OOE+OO 9.9BE-OI 

4.00E+02 8.37E-OB I.03E-03 O.OOE+OO 9.98E-OI 

5.00E+02 8.30E-08 I.04E-03 O.OOE+OO 9.9BE-OI 

7.00E+02 8.15E-OB 1.06E-03 O.OOE+OO 9.9BE-OI 

8.00E+02 B.08E-OB I.07E-03 O.OOE+OO 9.98E-OI 

9.00E+02 B.OIE-OB I.07E-G3 O.OOE+OO 9.98E-OI ,( I.OOE+03 7.94E-08 I.OBE-03 O.OOE+OO 9.98E-OI ," . 

2.00E+03 7.29E-OB 1.16E-03 O.OOE+OO 9.98E-OI 

3.00E+03 6.6BE-08 1.23E-03 O.OOE+OO 9.9BE-OI 

4.00E+03 6.13E-OB 1.29E-03 O.OOE+OO 9.98E-OI 

5.00E+03 5.62E-08 1.35E-03 O.OOE+OO 9.98E-OI 

7.00E+03 4.72E-08 1.45E-03 O.OOE+OO 9.9BE-OI 

8.00E+03 4.33E-08 1.50E-03 O.OOE+OO 9.98E-OI 

9.00E+03 3.97E-08 1.54E-03 O.OOE+OO 9.98E~OI 

I.OOE+04 3.64E-08 1.58E-03 O.OOE+OO 9.98E-Ol 

2.00E+04 1.53E-OB 1.82E-03 O.OOE+OO 9.98E-OI 

B-558 
INGESTIPN f 1- 1.00£-02 srABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-OI 3.00E-03 9. 96E-OI 9. 99E-Ol 

2.00E-OI 6.0lE-03 9. 88E-OI 9. 94E-OI 

3.00E-OI 7. 75E-03 9. 73E-Ol 9.8IE-OI 

4.00E-OI 8. 69E-03 9.50E-OI 9.58E-OI 

5.00E-0l 9.I8E-03 9.I9E-OI 9. 28E-OI 

6.00E-OI 9. 42E-03 8. 83E-OI 8. 92E-OI 

7.00E-Ol 9. 52E-03 8.42E-OI 8.5IE-Ol 

8.00E-OI 9. 55E-03 7. 98E-OI 8.07E-OI 

9.00E-OI 9. 54E-03 7. 52E-OI 7. 62E-Ol 

I.OOE+OO 9. 52E-03 7.06E-OI 7.I5E-OI 

2.00E+OO 9.03E-03 3.20E-Ol 3. 29E-Ol 

3.00E+OO 8. 57E-03 1.27E-OI 1. 36E-OI 

4.00E+OO 8.I6E-03 4.83E-02 5.65E-02 

5.00E+OO 7. 79E-03 1.80E-02 2. 58E-02 

6.00E+OO 7. 45E-03 6. 66E-03 1.4lE-02 

7.00E+OO 7.l6E-03 2. 46E-03 9.6lE-03 

8.00E+OO 6. 89E-03 9.05E-04 7.80E-03 

9.00E+OO 6. 65E-03 3. 33E-04 6. 99E-03 

1.OOE+Ol 6"; 44E-03 1. 23E-04 6. 56E-03 

2.00E+Ol 5.l7E-03 O.OOE+OO 5.l7E-03 

3.00E+Ol 4. 67E-03 O.OOE+OO 4.67E-03 

4.00E+Ol 4.40E-03 O.OOE+OO 4.40E-03 

5.00E+Ol 4. 22E-03 O.OOE+OO 4. 22E-03 

6.00E+Ol 4.07E-03 O.OOE+OO 4.07E-03 

7.00E+Ol 3. 93E-03 O.OOE+OO 3. 93E-03 

8.00E+Ol 3. 79E-03 O.OOE+OO 3. 79E-03 

9.00E+Ol 3. 66E-03 O.OOE+OO 3. 66E-03 

1.OOE+02 3. 54E-03 O.OOE+OO 3. 54E-03 

2.00E+02 2.50E-03 O.OOE+OO 2.50E-03 

3.00E+02 1.77E-03 O.OOE+OO 1.77E-03 

4.00E+02 1. 25E-03 O.OOE+OO 1. 25E-03 

5.00E+02 8. 83E-04 O.OOE+OO 8. 83E-04 

6.00E+02 6. 24E-04 O.OOE+OO 6. 24E-04 

7.00E+02 4.4lE-04 O.OOE+OO 4.4lE-04 

8.00E+02 3.J2E-04 O.OOE+OO 3.l2E-04 

9.00E+02 2.20E-04 O.OOE+OO 2.20E-04 

1.OOE+03 1. 56E-04 O.OOE+OO 1. 56E-04 

2.00E+03 4. 84E-06 O.OOE+OO 4. 84E-06 

3.00E+03 I.SlE-07 O.OOE+OO 1.51E-07 

B-559 
INGESTION f l = I.OOE-02 STABLE NIOBIUM 93 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 7. 43E-06 6.09E-04 

2.00E-Ol 3. 49E-05 S.89E-03 

3.00E-Ol 7. 63E-05 1. 93E-02 

4.00E-Ol 1.2SE-04 4.l4E-02 

S.OOE-Ol 1. 78E-04 7.l4E-02 

6.00E-Ol 2. 32E-04 1.08E-Ol 

7.00E-Ol 2. 88E-04 1. 49E-Ol 

8.00E-Ol 3. 43E-04 1. 92E-Ol 

9.00E-Ol 3. 98E-04 2. 38E-Ol 

1.OOE+OO 4.S3E-04 4.S3E-04 2. 84E-Ol 2. 84E-Ol 

2.OOE+OO S.17E-04 9. 69E-04 3. 86E-Ol 6.70E-0l 

3.00E+OO 4. 62E-04 1.43E-03 1. 93E-Ol 8. 63E-Ol 

4.00E+OO 4.13E-04 1. 84E-03 7. 89E-02 9.42E-Ol 

S.OOE+OO 3.70E-04 2.2lE-03 3.03E-02 9. 72E-Ol 

6.00E+OO 3.3lE-04 2.SSE-03 1.13E-02 9. 83E-Ol 

7.00E+OO 2. 97E-04 2. 84E-03 4.2lE-03 9. 88E-Ol 

8.00E+OO 2. 66E-04 3.llE-03 1.SSE-03 9. 89E-Ol 

9.00E+OO 2. 39E-04 3.3SE-03 5. 72E-04 9.90E-Ol 

1.OOE+Ol 2.l4E-04 3.S6E-03 2.lOE-04 9.90E-Ol 

2.OOE+Ol 7.8lE-OS 4. 83E-03 O.OOE+OO 9.90E-Ol 

3.00E+Ol 3.SlE-OS S.33E-03 O.OOE+OO 9.90E-Ol 

4.00E+Ol 2.l2E-05 S.60E-03 O.OOE+OO 9.90E-Ol 

S.OOE+Ol 1. 65E-OS 5. 78E-03 O.OOE+OO 9.90E-Ol 

6.00E+Ol 1.47E-OS S.93E-03 O.OOE+OO 9.90E-Ol 

7.00E+Ol 1. 38E-05 6.07E-03 O.OOE+OO 9.90E-Ol 

8.00E+Ol l.32E-OS 6.2lE-03 O.OOE+OO 9.90E-Ol 

9.00E+Ol l.27E-OS 6.34E-03 O.OOE+OO 9.90E-Ol 

1.OOE+02 l.23E-05 6. 46E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 8. 69E-06 7.S0E-03 O.OOE+OO 9.90E-Ol 

3.00E+02 6.l4E-06 8. 23E-03 O.OOE+OO 9.90E-Ol 

4.00E+02 4. 34E-06 8. 75E-03 O.OOE+OO 9.90E-Ol 

S.OOE+02 3.07E-06 9.l2E-03 O.OOE+OO 9.90E-'Ol 

6.00E+02 2.l7E-06 9.38E-03 O.OOE+OO 9.90E-Ol 

7.00E+02 l.S3E-06 9.S6E-03 O.OOE+OO 9.90E-ol 

8.00E+02 l.08E-06 9. 69E-03 O.OOE+OO 9.90E-Ol 

9.00E+02 7. 66E-07 9. 78E-03 O.OOE+OO 9.90E-Ol 

l.OOE+03 5.4lE-07 9. 84E-03 O.OOE+OO 9.90E-Ol 

2.00E+03 1. 68E-08 1.OOE-02 O.OOE+OO 9.90E-ol 

B-S60 
INGESTION £1= 1.00£-02 IlALPLIn... 3 • .52£+0 1 DAYS NIOBIUM 9.5 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 3.00E-03 9. 94E-OI 9. 97E-OI 

2.00E-Ol S.99E-03 9.S4E-Ol 9.90E-Ol 

3.00E-OI 7.7lE-03 9. 67E-OI 9.7SE-Ol 

4.00E-Ol S.62E-03 9.42E-Ol 9.S1E-0l 

S.OOE-Ol 9.09E-03 9.10E-Ol 9.19E-Ol 

6.00E-Ol 9.30E-03 S.72E-OI S.S2E-Ol 

7.00E-OI 9. 39E-03 S.30E-Ol S.40E-Ol 

S.OOE-Ol 9.40E-03 7.SSE-Ol 7.9SE-Ol 

9.00E-Ol 9.3SE-03 7. 39E-Ol 7.4SE-Ol 

I.OOE+OO 9. 33E-03 6. 92E-Ol 7.01E-Ol 

2.00E+OO S.6SE-03 3.0SE-Ol 3.16E-Ol 

3.00E+OO S.OSE-03 1.20E-Ol 1.2SE-Ol 

4.00E+OO 7.S4E-03 4. 46E-02 S.22E-02 

S.OOE+OO 7.0SE-03 1. 63E-02 2. 34E-02 

6.00E+OO 6. 62E-03 S.92E-03 1.2SE-02 

7.00E+OO 6. 23E-03 2.14E-03 S.3SE-03 

S.OOE+OO S.S9E-03 7.73E-04 6;66E-03 

9.00E+OO S.S7E-03 2. 79E-04 S.SSE-03 

1.OOE+Ol S.29E-03 1.OlE-04 S.39E-03· 

2.00E+Ol 3. 49E-03 O.OOE+OO 3. 49E-03 

3.00E+OI 2.SSE-03 O.OOE+OO 2.SSE-03 

4.00E+OI 2.00E-03 O.OOE+OO 2.00E-03 

S.OOE+Ol I.SSE-03 O.OOE+OO 1.SSE-03 

6.00E+OI 1. 25E-03 O.OOE+OO 1.25E-03 

7.00E+Ol 9.S7E-04 O.OOE+OO 9.S7E-04 

S.OOE+OI 7.S3E-04 O.OOE+OO 7.S3E-04 

9.00E+Ol 6.2IE-04 O.OOE+OO 6.2IE-04 

1.OOE+02 4. 92E-04 O.OOE+OO 4. 92E-04 

2.00E+02 4.S4E-05 O.OOE+OO 4.S4E-05 

3.00E+02 4. 76E-06 O.OOE+OO 4. 76E-06 

4.00E+02 4.69E-07 O.OOE+OO 4. 69E-07 

5.00E+02 4.61E-OS O.OOE+OO 4.61E-OS 

B-561 
INGESTION £1= 1.00E-02 BALFLIFE= 3.52E+01 DAYS NIOBIUM 95 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- -----------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7.41E-06 6.08E-04 

2.00E-Ol 3. 48E-OS S.87E-03 

3.00E-Ol 7.S8E-OS 1.92E-02 

4.00E-Ol 1. 24E-04 4. lIE-02 

S.OOE-Ol 1.76E-04 7.07E-02 

6.00E-Ol 2.30E-04 1.06E-Ol 

7.00E-Ol 2. 84E-04 1. 46E-Ol 

8.00E-Ol 3. 38E-04 1. 89E-Ol 

9.00E-OI 3. 91E-04 2. 34E-Ol 

I.OOE+OO 4. 44E-04 4. 44E-04 2. 79E-OI 2. 79E-OI 

2.00E+OO 4. 97E-04 9. 32E-04 3.71E-0l 6. 44E-OI 

3.00E+OO 4. 36E-04 I.3SE-03 1. 82E-OI 8.13E-OI 

4.00E+OO 3. 82E-04 I.70E-03 7.29E-02 8.70E-Ol 

S.OOE+OO 3.3SE-04 2. OlE-03 2. 75E-02 8.8IE-OI 

6~OOE+OO 2. 94E-04 2. 26E-03 I.OIE-02 8. 74E-OI 

7.00E+OO 2.S8E-04 2. 48E-03 3.66E-03 8.60E-OI 

8.00E+OO 2. 27E-04 2.6SE-03 I.33E-03 8. 4 SE-O 1 

9.00E+OO 2.00E-04 2.80E-03 4. 79E-04 8. 29E-OI 

I.OOE+OI 1. 76E-04 2. 92E-03 1.73E-04 8.I3E-Ol 

2.00E+OI S.27E-OS 3.2SE-03 O.OOE+OO 6. 67E-OI 

3.00E+OI 1. 94E-OS 2.9SE-03 O.OOE+OO S.48E-Ol 

4.00E+Ol 9. 64E-06 2. 54E-03 O.OOE+OO 4.50E--:-Ol 

S.OOE+Ol 6.I7E-06 2.I6E-03 O.OOE+OO 3. 69B-OI 

6.00E+OI 4.SIE-06 I.82E-03 O.OOE+OO 3.03E-OI 

7.00E+OI 3. 48E-06 I.S3E-03 O.OOE+OO 2. 49E-OI 

8.00E+OI 2. 73E-06 1. 28E-03 O.OOE+OO 2.04E-OI 

9.00E+OI 2.I6E-06 I.07E-03 O.OOE+OO I.68E-0l 

I.OOE+02 I.71E-06 9.00E-04 O.OOE+OO 1.3aE-OI 

2.00E+02 1. 68E-07 I.4SE-04 O.OOE+OO I.92E-02 

3.00E+02 1. 66E-08 2. 22E-OS O.OOE+OO 2. 67E-03 

B-S62 
INGESTION f I""' 8.00E-ol STABLE KOLYBDENUH 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol S.94E-Ol 4.0JE-Ol 9.97E-Ol 

2.00E-Ol 7.67E-Ol 2. 22E-Ol 9. 89E-Ol 

J.OOE-Ol 7.84E-Ol 1.9SE-Ol 9. 78E-Ol 

4.00E-Ol 7.80E-Ol 1. 86E-Ol 9. 66E-Ol 

S.OOE-Ol 7.7SE-Ol 1.17E-Ol 9.SJE-Ol 

6.00E-Ol 7.70E-Ol 1. 68E-Ol 9.J9E-Ol 

7.00E-0l 7. 66E-Ol 1.S9E-Ol 9.2SE-Ol 

8.00E-Ol 7.61E-Ol 1.49E-Ol 9.11E-Ol 

9.00E-Ol 7.S7E-Ol 1.40E-Ol 8. 97E-Ol 

1.OOE+OO 7.SJE-Ol 1. JOE-Ol 8.8JE-Ol 

2.00E+OO 7. 22E-Ol S.70E-02 7.79E-Ol 

J.OOE+OO 7.02E-Ol 2. 24E-02 7. 24E-Ol 

4.00E+OO 6. 87E-Ol 8.46E-OJ 6.96E-Ol 

S.OOE+OO 6.7SE-Ol J.lSE-OJ 6. 78E-Ol 

6.00E+OO 6.6SE-Ol 1.16E-03 6. 66E-Ol 

7.00E+OO 6.SSE-Ol 4. 29E-04 6.SSE-Ol 

8.00E+OO 6.4SE-Ol 1. S8E-04 6. 46E-Ol 

9.00E+OO 6.36E-Ol S.81E-OS 6. 36E-Ol 

1.OOE+Ol 6. 28E-Ol 2.14E-OS 6. 28E-Ol 

2.00E+OI S.46E-Ol O.OOE+OO S.46E-OI 

J.OOE+OI 4. 76E-OI O.OOE+OO 4. 76E-Ol 

4.00E+OI 4.14E-Ol O.OOE+OO 4.14E-Ol 

S.OOE+OI J.60E-Ol O.OOE+OO 3.60E-OI 

6.00E+Ol J.14E-Ol O.OOE+OO J.14E-Ol 

7.00E+Ol 2. 13E-Ol O.OOE+OO 2. 73E-OI 

8.00E+Ol 2.J8E-OI O.OOE+OO 2. 38E-OI 

9.00E+0l 2.07E-Ol O.OOE+OO 2.07E-OI 

I.OOE+02 1.80E-Ol O.OOE+OO 1.80E':"'OI 

2.00E+02 4.S1E-02 O.OOE+OO 4.SIE-02 

3.00E+02 1.13E-02 O.OOE+OO 1.IJE-02 

4.00E+02 2. 82E-03 O.OOE+OO 2.82E-03 

S.OOE+02 7.0SE-04 O.OOE+OO 7.0SE-04 

6.00E+02 I. 76E-04 O.OOE+OO I. 76E-04 

7.00E+02 4.4IE-OS O.OOE+OO 4.4IE-OS 

8.00E+02 1.1OE-OS O.OOE+OO 1.1OE-OS 

9.00E+02 2. 76E-06 O.OOE+OO 2. 76E-06 

1.OOE+03 6. 89E-07 O.OOE+OO 6. 89E-07 

B-S63 
INGESTIOII f}= 8.00E-Ql STABLK HOLDDENUM 96 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------ SYSTEMIC NON-SYSTEMIC 

-------------------- -------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2. 39E-03 4.0SE-04 

2.00E-Ol 7. 93E-03 2. 93E-03 

3.00E-Ol 1.38E-02 7. 86E-03 

4.00E-Ol 1. 93E-02 l.46E-02 

S.OOE-Ol 2. 46E-02 2.27E-02 

6.00E-Ol 2. 96E-02 3.l6E-02 

7.00E-Ol 3. 43E-02 4.lOE-02 

8.00E-Ol 3. 88E-02 S.07E-02 

9.00E-Ol 4.30E-02 6.03E-02 

1.00E+OO 4.70E-02 4.70E-02 6. 98E-02 6. 98E-02 

2.00E+OO 3.09E-02 7.79E-02 7.33E-02 1.43E-Ol 

3.00E+OO 2.02E-02 9.8lE-02 3. 46E-02 1. 78E-Ol 

4.00E+OO 1. 48E-02 1.13E-OI 1. 39E-02 1.92E-Ol 

S.OOE+OO 1.20E-02 1.2SE-Ol S.3lE-03 1. 97E-Ol 

6.00E+OO 1.06E-02 1.3SE-Ol 1. 98E-03 1. 99E-Ol 

7.00E+OO 9. 79E-03 1.4SE-Ol 7.3SE-04 2.00E-Ol 

8.00E+OO 9. 33E-03 1. SSE-Ol 2.71E-04 2.00E-0l 

9.00E+OO 9.04E-03 1. 64E-Ol 9. 98E-OS 2.00E-Ol 

1.OOE+Ol 8. 84E-03 1. 72E-Ol 3. 67E-OS 2.00E-Ol 

2.00E+Ol 7. 62E-03 2.S4E-Ol O.OOE+OO 2.00E-Ol 

3.00E+Ol 6. 64E-03 3. 24E-Ol O.OOE+OO 2.00E-Ol 

4.00E+Ol S.78E-03 3. 86E-Ol O.OOE+OO 2.00E-Ol 

S.OOE+Ol S.03E-03 4.40E-Ol O.OOE+OO 2.00E-Ol 

6.00E+Ol 4. 38E-03 4. 86E-Ol O.OOE+OO 2.00E-Ol 

7.00E+Ol 3.8lE-03 S.27E-Ol O.OOE+OO 2.00E-Ol 

8.00E+Ol 3. 32E-03 S.62E-Ol O.OOE+OO 2.00E-Ol 

9.00E+Ol 2.89E-03 S.93E-Ol O.OOE+OO 2.00E-Ol 

1.OOE+02 2.S2E-03 6.20E-Ol O.OOE+OO 2.00E-Ol 

2.00E+02 6. 29E-04 7.SSE-Ol O.OOE+OO 2.00E-Ol 

3.00E+02 1.S7E-04 7. 89E-Ol O.OOE+OO 2.00E-Ol 

4.00E+02 3. 93E-OS 7. 97E-Ol O.OOE+OO 2.00E-Ol 

S.OOE+02 9. 84E-06 7. 99E-Ol O.OOE+OO 2.00E-Ol 

6.00E+02 2. 46E-06 8.00E-Ol O.OOE+OO 2.00E-Ol 

7.00E+02 6.1SE-07 8.00E-Ol O.OOE+OO 2.00E-ol 

8.00E+02 1. S4E-07 8.00E-Ol O.OOE+OO 2.00E-Ol 

9.00E+02 3.8SE-08 8.00E-Ol O.OOE+OO 2.00E-Ol 

B-S64 
INGESTION £1= 8.00&-01 BALFLlFE- 1.53&+09 DAYS TECHNETIUM 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 5. 85E-01 4.03E-01 9.88E-01 

2.00E-Ol 7. 36E-Ol 2. 22E-01 9.58E-Ol 

3.00E-01 7.29E-Ol 1. 95E-01 9. 24E-01 

4.00E-Ol 7.03E-01 1. 86E-01 8. 89E-Ol 

5.00E-Ol 6. 77E-Ol 1.77E-Ol 8. 54E-Ol 

6.00E-Ol 6.51E-Ol 1.68E-Ol 8.20E-Ol 

7.00E-01 6.27E-01 1.59E-Ol 7.86E-Ol 

8.00E-Ol 6.04E-01 1.49E-Ol 7. 54E-Ol 

9.00E-Ol 5. 82E-Ol 1.40E-Ol 7.22E-Ol 

1.00E+00 5.61E-01 1.30E-Ol 6. 92E-Ol 

2.00E+00 3.96E-01 5.70E-02 4. 53E-Ol 

3.00E+00 2. 87E-Ol 2. 24E-02 3.09E-Ol 

4.00E+00 2. 13E-Ol 8. 46E-03 2.21E-01 

5.00E+00 1. 62E-Ol 3. 15E-03 1. 65E-Ol 

6.00E+00 1. 27E-01 1. 16E-03 1. 28E-Ol 

7.00E+00 1.02E-Ol 4. 29E-04 1.02E-Ol 

8.00E+00 8. 34E-02 1. 58E-04 8. 35E-02 

9.00E+00 6. 99E-02 5. 81E-05 7.00E"';02 

1.00E+Ol 5. 99E-02 2. 14E-05 5. 99E-02 

2.00E+Ol 2. 43E-02 O.OOE+OO 2. 43E-02 

3.00E+Ol 1. 55E-02 O.OOE+OO 1. 55E-02 

4.00E+Ol 1.10E-02 O.OOE+OO 1.10E-02 

5.00E+Ol 7. 98E-03 O.OOE+OO 7.98E-03 

6.00E+Ol 5. 82E-03 O.OOE+OO 5. 82E-03 

7.00E+Ol 4. 24E-03 O.OOE+OO 4. 24E-03 

8.00E+01 3.1OE-03 O.OOE+OO 3.1OE-03 

9.00E+Ol 2. 26E-03 O.OOE+OO 2. 26E-03 

1.00E+02 1. 65E-03 O.OOE+OO 1. 65E-03 

2.00E+02 7.07E-05 O.OOE+OO 7.07E-05 

3.00E+02 3.03E-06 O.OOE+OO 3.03E-06 

4.00E+02 1.30E-07 O.OOE+OO 1.30E-07 

,-. ' 

B-565 
INGESTION f1"" 8.00E-ol IlALPLIFE= 1.53E+09 DAYS TEClINETIUH 98 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------ ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS . EXCRETA EXCRETA FECES FECES 

1.00E-Ol 1. 19E-02 4.05E-04 

2.00E-Ol 3. 94E-02 2. 93E-03 

3.00E-Ol 6. 85E-02 7. 86E-03 

4.00E-Ol 9. 65E-02 1. 46E-02 

5.00E-Ol 1.23E-0l 2. 27E-02 

6.00E-Ol 1. 49E-Ol 3. 16E-02 

7.00E-Ol 1. 73E-Ol 4.10E-02 

8.00E-Ol 1. 96E-Ol 5.07E-02 

9.00E-Ol 2. 18E-Ol 6.03E-02 

1.00E+00 2. 39E-Ol 2. 39E-Ol 6. 98E-02 6. 98E-02 

2.00E+00 1. 66E-Ol 4.04E-Ol 7.33E-02 1. 43E-Ol 

3.00E+00 1.09E-Ol 5. 13E-Ol 3. 46E-02 1. 78E-ol 

4.00E+00 7. 37E-02 5. 87E-Ol 1. 39E-02 1. 92E-Ol 

5.00E+00 5.07E-02 6. 38E-Ol 5. 31E-03 1. 97E-Ol 

6.00E+00 3. 55E-02 6. 73E-Ol 1.98E-03 1.99E-Ol 

7.00E+00 2. 52E-02 6. 98E-Ol 7. 35E-04 2.00E-Ol 

8.00E+00 1. 82E-02 7. 17E-Ol 2.71E-04 2.00E-Ol 

9.00E+00 1. 34E-02 7.30E-Ol 9. 98E-05 2.00E-Ol 

1.00E+Ol 1.01E-02 7.40E-Ol 3. 67E-05 2.00E-Ol 

2.00E+Ol 1.47E-03 7. 76E-Ol O.OOE+OO 2.00E-Ol 

3.00E+Ol 5. 96E-04 7. 84E-Ol O.OOE+OO 2.00E-Ol 

4.00E+Ol 3. 67E-04 7.89E-Ol O.OOE+OO 2.00E-Ol 

5.00E+Ol 2. 58E-04 7. 92E-Ol O.OOE+OO 2.00E-Ol 

6.00E+Ol 1. 87E-04 7. 94E-Ol O.OOE+OO 2.00E-Ol 

7.00E+Ol 1. 36E-04 7. 96E-Ol O.OOE+OO 2.00E-Ol 

8.00E+Ol 9. 91E-05 7. 97E-01 O.OOE+OO 2.00E-Ol 

9.00E+Ol 7.23E-05 7. 98E-Ol O.OOE+OO 2.00E-Ol 

1.00E+02 5. 28E-05 7. 98E-Ol O.OOE+OO 2.00E-01 

2.00E+02 2. 26E-06 8.00E-01 O.OOE+OO 2.00E-01 

3.00E+02 9. 69E-08 8.00E-Ol O.OOE+OO 2.00E-Ol 

B-566 
INGESTION f 1- 5.ooE-02 STABLE RUTHENIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 1. 53E-02 9.84E-Ol 9. 99E-Ol 

2.00E-Ol 2. 99E-02 9.63E-Ol 9.93E-Ol 

3.00E-Ol 3.77E-02 9.41E-Ol 9.79E-Ol 

4.00E-Ol 4. 14E-02 9.15E-Ol 9.56E-Ol 

5.00E-01 4. 29E-02 8. 83E-Ol 9.26E-Ol 

6.00E-Ol 4. 34E-02 8.46E-Ol 8.90E-Ol 

7.00E-01 4. 33E-02 8.06E-Ol 8. 49E-Ol 

8.00E-Ol 4.30E-02 7.63E-Ol 8.06E-Ol 

9.00E-01 4. 26E-02 7.19E-01 7. 62E-Ol 

1.00E+00 4. 23E-02 6. 74E-01 7.17E-Ol 

2.00E+00 3. 96E-02 3.05E-Ol 3.45E-Ol 

3.00E+00 3. 79E-02 1.21E-Ol 1.59E-Ol 

4.00E+00 3. 65E-02 4.60E-02 8.25E-02 

5.00E+00 3. 52E-02 1.71E-02 5. 23E-02 

6.00E+00 3. 39E-02 6.34E-03 4.03E-02 

7.00E+00 3. 28E-02 2. 34E-03 3.51E-02 

8.00E+00 3.17E-02 8.61E-04 3. 26E-02 

9.00E+00 3.07E-02 3. 17E-04 3.1OE-02 

1.00E+01 2. 98E-02 1. 17E-04 2. 99E-02 

2.00E+Ol 2.31E-02 O.OOE+OO 2.31E-02 

3.00E+01 1.94E-02 O.OOE+OO 1. 94E-02 

4.00E+Ol 1. 71E-02 O.OOE+OO 1. 71E-02 

5.00E+01 1.55E-02 O.OOE+OO 1. 55E-02 

6.00E+Ol 1. 43E-02 O.OOE+OO 1. 43E-02 

7.00E+Ol 1. 33E-02 O.OOE+OO 1.33E-02 

8.00E+Ol 1.26E-02 O.OOE+OO 1. 26E-02 

9.00E+Ol 1. 19E-02 O.OOE+OO 1. 19E-02 

1.00E+02 1. 14E-02 O.OOE+OO 1. 14E-02 

2.00E+02 8. 99E-03 O.OOE+OO 8. 99E-03 

3.00E+02 8. 16E-03 O.OOE+OO 8. 16E-03 

4.00E+02 7. 59E-03 O.OOE+OO 7.59E-03 

5.00E+02 7.07E-03 O.OOE+OO 7.07E-03 

6.00E+02 6.60E-03 O.OOE+OO 6.60E-03 

7.00E+02 6. 16E-03 O.OOE+OO 6. 16E-03 

8.00E+02 5. 74E-03 O.OOE+OO 5. 74E-03 

9.00E+02 5. 36E-03 O.OOE+OO 5. 36E-03 

1.00E+03 5.00E-03 O.OOE+OO 5.00E-03 

2.00E+03 2.50E-03 O.OOE+OO 2.50E-03 

3.00E+03 1. 25E-03 O.OOE+OO 1.25E-03 

4.00E+03 6. 25E-04 O.OOE+OO 6. 25E-04 

5.00E+03 3. 13E-04 O.OOE+OO 3. 13E-04 

6.00E+03 1. 56E-04 O.OOE+OO 1. 56E-04 

7.00E+03 7. 82E-05 O.OOE+OO 7.82E-05 

8.00E+03 3. 91E-05 O.OOE+OO 3.91E-05 

9.00E+03 1.96E-05 O.OOE+OO 1.96E-05 

1.00E+04 9.78E-06 O.OOE+OO 9. 78E-06 

B-567 
INGESTION fl= 5.00&-02 STABLE RUTHENIUM 101 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2. 33E-04 6.06E-04 

2.00E-01 1.02E-03 5. 83E-03 

3.00E-01 2.08E-03 1.90E-02 

4.00E-01 3. 17E-03 4.07E-02 

5.00E-01 4. 18E-03 6. 99E-02 

6.00E-01 5.08E-03 1.05E-01 

7.00E-01 5. 87E-:-03 1.45E-01 

8.00E-01 6. 54E-03 1. 87E-01 

9.00E-01 7. 12E-03 2. 31E-01 

1.00E+00 7. 62E-03 7. 62E-03 2. 76E-01 2. 76E-01 

2.00E+00 2. 81E-03 1.04E-02 3.69E-01 6.45E-01 

3.00E+00 1. 65E-03 1. 21E-02 1. 84E-01 8. 29E-01 

4.00E+00 1. 44E-03 1. 35E-02 7.52E-02 9.04E-01 

5.00E+00 1. 33E-03 1.48E-02 2. 89E-02 9. 33E-01 

6.00E+00 1. 23E-03 1.61E-02 1.08E-02 9. 44E-01 

7.00E+00 1. 15E-03 1.72E-02 4.00E-03 9.48E-01 

8.00E+00 1.07E-03 1. 83E-02 1.48E-03 9.49E-01 

9.00E+00 9. 98E-04 1. 93E-02 5. 44E-04 9.50E-01 

1.00E+01 9.32E-04 2.02E-02 2.00E-04 9.50E-01 

2.00E+01 4. 95E-04 2.69E-02 O.OOE+OO 9.50E-01 

3.00E+01 2. 93E-04 3.06E-02 O.OOE+OO 9.50E-01 

4.00E+01 1. 94E-04 3. 29E-02 O.OOE+OO 9.50E-01 

5.00E+01 1.40E-04 3. 45E-02 O.OOE+OO 9.50E-01 

6.00E+01 1.07E-04 3. 57E-02 O.OOE+OO 9.50E-01 

7.00E+01 8. 57E-05 3. 67E-02 O.OOE+OO 9.50E-01 

8.00E+01 6. 99E-05 3. 74E-02 O.OOE+OO 9.50E-01 

9.00E+01 5. 79E-05 3. 81E-02 O.OOE+OO 9.50E-01 

1.00E+02 4. 83E-05 3. 86E-02 O.OOE+OO 9.50E-01 

2.00E+02 1. 18E-05 4.10E-02 O.OOE+OO 9.50E-01 

3.00E+02 6. 42E-06 4. 18E-02 O.OOE+OO 9.50E-01 

4.00E+02 5. 36E-06 4. 24E-02 O.OOE+OO 9.50E-01 

5.00E+02 4. 92E-06 4. 29E-02 O.OOE+OO 9.50E-01 

6.00E+02 4. 58E-06 4. 34E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 4. 27E-06 4. 38E-02 O.OOE+OO 9.50E-01 

8.00E+02 3. 98E-06 4. 43E-02 O.OOE+OO 9.50E-01 

9.00E+02 3.72E-06 4. 46E-02 O.OOE+OO 9.50E-01 

1.00E+03 3. 47E-06 4.50E-02 O.OOE+OO 9.50E-01 

2.00E+03 1. 73E-06 4. 75E-02 O.OOE+OO 9.50E-01 

3.00E+03 8."67E-07 4. 87E-02 O.OOE+OO 9.50E-01 

4.00E+03 4. 34E-07 4. 94E-02 O.OOE+OO 9.50E-Ol 

5.00E+03 2. 17E-07 4. 97E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 5. 42E-08 4. 99E-02 O.OOE+OO 9.50E-Ol 

8.00E+03 2. 71E-08 5.00E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 1. 36E-08 5.00E-02 O.OOE+OO 9.50E-01 

B-568 
INGESTION f1= 5.00£-02 STABLE RHODIUM 103 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. S3E-02 9.84E-ol 9. 99E-Ol 

2.00E-Ol 2. 99E-02 9.63E-Ol 9.93E-Ol 

3.00E-Ol 3.77E-02 9.41E-Ol 9.79E-Ol 

4.00E-Ol 4. 14E-02 9.1SE-Ol 9.S6E-Ol 

5.00E-Ol 4. 29E-02 8. 83E-Ol 9. 26E-Ol 

6.00E-Ol 4. 34E-02 8.46E-Ol 8.90E-Ol 

7.00E-Ol 4.33E-02 8.06E-Ol 8. 49E-Ol 

8.00E-Ol 4.30E-02 7.63E-Ol 8.06E-Ol 

9.00E-Ol 4.26E-02 7.19E-Ol 7.62E-0l 

1.OOE+OO 4.23E-02 6. 74E-Ol 7.17E-OI 

2.00E+OO 3.96E-02 3.05E-Ol 3. 45E-Ol 

3.00E+OO 3. 79E-02 1.21E-Ol 1. 59E-OI 

4.00E+OO 3.65E-02 4.60E-02 8.2SE-02 

5.00E+OO 3.S2E-02 1.71E-02 5. 23E-02 

6.00E+OO 3. 39E-02 6. 34E-03 4.03E-02 

7.00E+OO 3. 28E-02 2. 34E-03 3.51E-02 

8.00E+OO 3. 17E-02 8.61E-04 3. 26E-02 

9.00E+OO 3.07E-02 3.17E-04 3.10E-02 

1.OOE+Ol 2. 98E-02 1. 17E-04 2.99E-02 

2.00E+Ol 2.31E-02 O.OOE+OO 2.3IE-02 

3.00E+Ol 1. 94E-02 O.OOE+OO 1.94E-02 

4.00E+Ol 1.71E-02 O.OOE+OO I.71E-02 

S.OOE+Ol 1.55E-02 O.OOE+OO 1.5SE-02 

6.00E+Ol 1.43E-02 O.OOE+OO 1. 43E-02 

7.00E+Ol I.33E-02 O.OOE+OO 1. 33E-02 

8.00E+OI 1.26E-02 O.OOE+OO 1. 26E-02 

9.00E+Ol I.19E-02 O.OOE+OO 1. 19E-02 

1.00E+02 1. 14E-02 O.OOE+OO 1.14E-02 

2.00E+02 8. 99E-03 O.OOE+OO 8. 99E-03 

3.00E+02 8.16E-03 O.OOE+OO 8.I6E-03 

4.00E+02 7.59E-03 O.OOE+OO 7.S9E-03 

5.00E+02 7.07E-03 O.OOE+OO 7.07E-03 

6.00E+02 6.60E-03 O.OOE+OO 6.60E-03 

7.00E+02 6. 16E-03 O.OOE+OO 6.16E-03 

8.00E+02 5. 74E-03 O.OOE+OO S.74E-03 

9.00E+02 5. 36E-03 O.OOE+OO S.36E-03 

'. 1.00E+03 5.00E-03 O.OOE+OO 5.00E-03 " , 

2.00E+03 i",' '.' 2.50E-03 O.OOE+OO 2.50E-03 

3.00E+03 I.2SE-03 O.OOE+OO 1.25E-03 

4.00E+03 6.2SE-04 O.OOE+OO 6.2SE-04 

S.OOE+03 3.13E-04 O.OOE+OO 3.13E-04 

6.00E+03 1. 56E-04 O.OOE+OO 1. 56E-04 

7.00E+03 7. 82E-OS O.OOE+OO 7. 82E-05 

8.00E+03 3.91E-OS O.OOE+OO 3.91E-OS 

9.00E+03 1. 96E-OS O.OOE+OO 1. 96E-05 

1.OOE+04 9. 78E-06 O.OOE+OO 9. 78E-06 

B-569 
INGESTION fl= 5.00E-02 STABLE RHODIUM. 103 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2.33E-04 6.06E-04 

2.00E-Ol 1.02E-03 5. 83E-03 

3.00E-Ol 2.08E-03 1.90E-02 

4.00E-Ol 3. 17E-03 4.07E-02 

5.00E-Ol 4. 18E-03 6.99E-02 

6.00E-Ol 5.08E-03 1.05E-Ol 

7.00E-Ol 5.87E-03 1.45E-Ol 

8.00E-Ol 6.54E-03 1. 87E-Ol 

9.00E-Ol 7. 12E-03 2.31E-01 

1.00E+00 7. 62E-03 7.62E-03 2. 76E-01 2. 76E-01 

2.00E+00 2.81E-03 1.04E-02 3. 69E-01 6.45E-Ol 

3.00E+00 1. 65E-03 1.21E-02 1.84E-01 8.29E-01 

4.00E+00 1.44E-03 1.35E-02 7.52E-02 9.04E-Ol 

5.00E+00 1.33E-03 1.48E-02 2. 89E-02 9. 33E-01 

6.00E+00 1. 23E-03 1.61E-02 1.08E-02 9.44E-01 

7.00E+00 1. 15E-03 1.72E-02 4.00E-03 9. 48E-Ol 

8.00E+00 1.07E-03 1.83E-02 1.48E-03 9.49E-01 

9.00E+00 9. 98E-04 1. 93E-02 5.44E-04 9.50E-Ol 

1.00E+Ol 9.32E-04 2.02E-02 2.00E-04 9.50E-Ol 

2.00E+Ol 4. 95E-04 2. 69E-02 O.OOE+OO 9.50E-01 

3.00E+Ol 2. 93E-04 3.06E-02 O.OOE+OO 9.50E-01 

4.00E+Ol 1. 94E-04 3. 29E-02 O.OOE+OO 9.50E-Ol 

5.00E+Ol 1.40E-04 3.45E-02 O.OOE+OO 9.50E-01 

6.00E+Ol 1.07E-04 3. 57E-02 O.OOE+OO 9.50E-Ol 

7.00E+01 8. 57E-05 3.67E-02 O.OOE+OO 9.50E-Ol 

8.00E+Ol 6.99E--05 3. 74E-02 O.OOE+OO 9.50E-Ol 

9.00E+Ol 5. 79E-05 3.81E-02 O.OOE+OO 9.50E-Ol 

1.00E+02 4. 83E-05 3.86E-02 O.OOE+OO 9.50E-Ol 

2.00E+02 1. 18E-05 4.10E-02 O.OOE+OO 9.50E-Ol 

3.00E+02 6.42E-06 4. 18E-02 O.OOE+OO 9.50E-Ol 

4.00E+02 5. 36E-06 4. 24E-02 O.OOE+OO 9.50E-Ol 

5.00E+02 4. 92E-06 4.29E-02 O.OOE+OO 9.50E-Ol 

6.00E+02 4.58E-06 4.34E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 4.27E-06 4.38E-02 O.OOE+OO 9.50E-Ol , , 8.00E+02 3. 98E-06 4.43E-02 O.OOE+OO 9.50E-Ol 

9.00E+02 3.72E-06 4.46E-02 O.OOE+OO 9.50E-Ol 

1.00E+03 3.47E-06 4.50E-02 O.OOE+OO 9.50E-Ol 

2.00E+03 1. 73E-06 4. 75E-02 O.OOE+OO 9.50E-Ol 

3.00E+03 8.67E-07 4. 87E-02 O.OOE+oo 9.50E-Ol 

4.00E+03 4. 34E-07 4. 94E-02 O.OOE+OO 9.50E-Ol 

5.00E+03 2. 17E-07 4. 97E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 5.42E-08 4. 99E-02 O.OOE+OO 9.50E-01 

8.00E+03 2.71E-08 5.00E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 1. 36E-08 5.00E-02 O.OOE+OO 9.50E-Ol 

B-570 
INGESTION f1= 5.00&-03 STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 1.45E-03 9.98E-01 9. 99E-Ol 

2.00E-01 2.80E-03 9.91E-01 9. 94E-01 

3.00E-01 3.47E-03 9.77E-Ol 9.80E-01 

4.00E-01 3. 75E-03 9. 54E-Ol 9. 58E-01 

5.00E-01 3. 83E-03 9. 24E-01 9.28E-01 

6.00E-01 3.81E-03 8.87E-Ol 8.91E-01 

7.00E-01 3. 75E-03 8.46E-01 8.50E-01 

8.00E-01 3. 68E-03 8.02E-01 8.06E-01 

9.00E-01 3. 61E-03 7. 56E-Ol 7.60E-Ol 

1.00E+00 3. 55E-03 7.10E-01 7. 13E-01 

2.00E+00 3. 23E-03 3. 22E-01 3.25E-01 

3.00E+00 3.08E-03 1. 28E-01 1. 31E-Ol 

4.00E+00 2. 94E-03 4. 86E-02 5. 15E-02 

5.00E+00 2.80E-03 1.81E-02 2.09E-02 

6.00E+00 2. 68E-03 6.70E-03 9. 38E-03 

7.00E+00 2. 56E-03 2.47E-03 5.03E-03 

8.00E+00 2. 44E-03 9.10E-04 3.35E-03 

9.00E+00 2. 33E-03 3. 35E-04 2. 67E-03 

1.00E+01 2. 23E-03 1.23E-04 2. 35E-03 

2.00E+01 1.40E-03 O.OOE+OO 1.40E-03 

3.00E+01 8. 84E-04 O.OOE+OO 8. 84E-04 

4.00E+01 5. 57E-04 O.OOE+OO 5. 57E-04 

5.00E+01 3. 51E-04 O.OOE+OO 3. 51E-04 

6.00E+Ol 2. 21E-04 O.OOE+OO 2. 21E-04 

7.00E+01 1.39E-04 O.OOE+OO 1. 39E-04 

8.00E+01 8.77E-05 O.OOE+OO 8.77E-05 

9.00E+01 5. 53E-05 O.OOE+OO 5. 53E-05 

1.00E+02 3. 48E-05 O.OOE+OO 3. 48E-05 

2.00E+02 3. 43E-07 O.OOE+OO 3. 43E-07 

8-571 
INGESTION fl= 5.00£-03 STABLE PALLADIUM 106 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4. 98E-OS 6.09E-04 

2.00E-OI 2. 16E-04 S.90E-03 

3.00E-01 4. 33E-04 1.93E-02 

4.00E-01 6.S1E-04 4.lSE-02 

S.OOE-01 8.47E-04 7. 16E-02 

6.00E-01 1.0IE-03 1.08E-Ol 

7.00E-Ol 1.lSE-03 1. 49E-01 

8.00E-Ol 1. 27E-03 1. 93E-01 

9.00E-01 1. 36E-03 2.39E-01 

1.OOE+OO 1.43E-03 1.43E-03 2.8SE-Ol 2.8SE-Ol 

2.00E+OO 3. 32E-04 1.77E-03 3. 88E-Ol 6.73E-01 

3.00E+OO 1.S7E-04 1.92E-03 1. 94E-01 8. 67E-01 

4.00E+OO 1.40E-04 2.06E-03 7. 94E-02 9. 46E-01 

S.OOE+OO 1. 33E-04 2.20E-03 3.0SE-02 9. 77E-01 

6.00E+OO 1.27E-04 2. 32E-03 1.14E-02 9. 88E-01 

7.00E+OO 1.2lE-04 2. 44E-03 4. 23E-03 9. 93E-01 

8.00E+OO 1.1SE-04 2.S6E-03 1. S6E-03 9. 94E-01 

9.00E+OO 1.10E-04 2. 67E-03 S.7SE-04 9.9SE-01 

1.OOE+01 1.0SE-04 2.77E-03 2. 12E-04 9.9SE-Ol 

2.00E+01 6. 63E-OS 3.60E-03 O.OOE+OO 9.9SE-Ol 

3.00E+01 4.l8E-OS 4.l2E-03 O.OOE+OO 9.9SE-Ol 

4. OOE+O 1 2. 63E-OS 4.44E-03 O.OOE+OO 9.9SE-Ol 

S.OOE+01 1. 66E-OS 4.6SE-03 O.OOE+OO 9.9SE-01 

6.00E+01 1.04E-0S 4. 78E-03 O.OOE+OO 9.9SE-Ol 

7.00E+01 6.S8E-06 4. 86E-03 O.OOE+OO 9.9SE-01 

8.00E+Ol 4.lSE-06 4.91E-03 O.OOE+OO 9.9SE-Ol 

9.00E+Ol 2.61E-06 4. 94E-03 O.OOE+OO 9.9SE-Ol 

1.OOE+02 1.6SE-06 4. 97E-03 O.OOE+OO 9.9SE-Ol 

2.00E+02 1. 62E-08 S.OOE-03 O.OOE+OO 9.9SE-Ol 

!" .. 

B-S72 
INGESTION f 1'''' 5.00£-02 STABLE SILVER 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 1. 55E-02 9.84E-01 9.99E-01 

2.00E-01 3.09E-02 9.63E-01 9. 94E-01 

3.00E-01 3. 96E-02 9.41E-01 9.81E-01 

4.00E-en 4. 42E-02 9. 15E-01 9. 59E-01 

5.00E-01 4. 66E-02 8. 83E-01 9.30E-01 

6.00E-01 4. 78E-02 8.46E-01 8. 94E-01 

7.00E-01 4. 84E-02 8.06E-01 8. 54E-01 

8.00E-01 4. 86E-02 7. 63E-01 8. 12E-01 

9.00E-01 4. 87E-02 7. 19E-01 7. 68E-01 

1.00E+00 4. 87E-02 6. 74E-01 7.23E-01 

2.00E+00 4. 74E-02 3.05E-01 3. 52E-01 

3.00E+00 4. 62E-02 1.21E-01 1. 67E-01 

4.00E+00 4.50E-02 4.60E-02 9.10E-02 

5.00E+00 4.40E-02 1.71E-02 6. 12E-02 

6.00E+00 4.31E-02 6. 34E-03 4. 95E-02 

7.00E+00 4. 23E-02 2. 34E-03 4. 46E-02 

8.00E+00 4. 15E-02 8. 61E-04 4.23E-02 

9.00E+00 4.07E-02 3. 17E-04 4.10E-02 

1.00E+01 4.00E-02 1. 17E-04 4.01E-02 

2.00E+01 3. 43E-02 O.OOE+OO 3. 43E-02 

3.00E+01 2. 98E-02 O.OOE+OO 2. 98E-02 

4.00E+01 2. 59E-02 O.OOE+OO 2. 59E-02 

5.00E+01 2. 26E-02 O.OOE+OO 2.26E-02 

6.00E+01 1.96E-02 O.OOE+OO 1. 96E-02 

7.00E+01 1. 71E-02 O.OOE+OO 1.71E-02 

8.00E+01 1. 49E-02 O.OOE+OO 1. 49E-02 

9.00E+01 1.30E-02 O.OOE+OO 1.30E-02 

1.00E+02 1. 13E-02 O.OOE+OO 1. 13E-02 

2.00E+02 2. 82E-03 O.OOE+OO 2. 82E-03 

3.00E+02 7.06E-04 O.OOE+OO 7.06E-04 

4.00E+02 1. 76E-04 O.OOE+OO 1. 76E-04 

5.00E+02 4. 41E-05 O.OOE+OO 4.41E-05 

6.00E+02 1. WE-OS O.OOE+OO 1. WE-OS 

7.00E+02 2. 76E-06 O.OOE+OO 2. 76E-06 

8.00E+02 6.90E-07 O.OOE+OO 6.90E-07 

9.00E+02 1. 73E-07 O.OOE+OO 1. 73E-07 . , ~. 

1.00E+03 .... .~ "." 4. 32E-08 O.OOE+OO 4. 32E-08 

B-573 
INGESTION £1= 5.00£-02 STABLE SILVER. 108 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ----------------------------------------~-------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATEP 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2.0BE-05 6.06E-04 

2.00E-Ol 9.7IE-05 5.B3E-03 

3.00E-Ol 2.llE-04 1.90E-02 

4.00E-Ol 3. 44E-04 4.07E-02 

5.00E-Ol 4.B7E-04 6. 99E-02 

6.00E-Ol 6. 35E-04 1.05E-Ol 

7.00E-Ol 7.B4E-04 1.45E-Ol 

B.OOE-Ol 9. 33E-04 1.B7E-Ol 

9.00E-Ol 1.08E-03 2.3lE-Ol 

1.OOE+OO 1. 23E-03 1. 23E-03 2. 76E-Ol 2. 76E-Ol 

2.00E+OO 1. 38E-03 2.6lE-03 3.69E-Ol 6.45E-Ol 

3.00E+OO 1. 23E-03 3. 84E-03 1. 84E-Ol 8. 29E-Ol 

4.00E+OO 1.11E-03 4.95E-03 7. 52E-02 9.04E-Ol 

5.00E+OO 1.OlE-03 5. 96E-03 2. 89E-02 9. 33E-Ol 

6.00E+OO 9.27E-04 6.B9E-03 1.08E-02 9.44E-Ol 

7.00E+OO 8. 57E-04 7. 75E-03 4.00E-03 9. 48E-Ol 

8.00E+OO 7. 97E-04 8. 54E-03 1.48E-03 9. 49E-Ol 

9.00E+OO 7.48E-04 9. 29E-03 5.44E-04 9.50E-Ol 

1.OOE+Ol 7.06E-04 1.OOE-02 2.00E-04 9.50E-Ol 

2.00E+Ol 4. 99E-04 1.57E-02 O.OOE+OO 9.50E-Ol 

3.00E+Ol 4.l9E-04 2.02E-02 O.OOE+OO 9.50E-Ol 

4.00E+Ol 3. 62E-04 2.4lE-02 O.OOE+OO 9.50E-Ol 

5.00E+Ol 3.l5E-04 2.74E-02 O.OOE+OO 9.50E-Ol 

6.00E+Ol 2. 74E-04 3.04E-02 O.OOE+OO 9.50E-Ol. 

7.00E+Ol 2. 39E-04 3. 29E-02 O.OOE+OO 9.50E-Ol 

8.00E+Ol 2.08E-04 3.51E-02 O.OOE+OO 9.50E-Ol 

9.00E+Ol 1.8lE-04 3.70E-02 O.OOE+OO 9.50E-Ol 

l.OOE+02 l.57E-04 3. 87E-02 O.OOE+OO 9.50E-Ol 

2.00E+02 3. 94E-05 4.72E-02 O.OOE+OO 9.50E-Ol 

3.00E+02 9. 85E-06 4. 93E-02 O.OOE+OO 9.50E-Ol 

4.00E+02 2. 46E-06 4. 98E-02 O.OOE+OO 9.50E-Ol 

5.00E+02 6.l6E-07 5.-00E-02 O.OOE+OO 9.50E-Ol 

6.00E+02 1.54E-07 5.00E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 3. 85E-08 5.00E-02 O.OOE+OO 9.50E-Ol 

B-574 
INGESTION fl"" 5.00E-02 STABLE CADMIUM 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 55E-02 9.84E-Ol 9.99E-Ol 

2.00E-Ol 3.10E-02 9.63E-Ol 9.94E-Ol 

3.00E-01 3.98E-02 9.41E-Ol 9.81E-01 

4.00E-01 4.46E-:02 9.15E-Ol 9.59E-01 

5.00E-01 4.71E-02 8.83E-Ol 9.30E-01 

6.00E-01 4.85E-02 8.46E-01 8.95E-Ol 

7.00E-01 4.92E-02 8.06E-01 8.55E-Ol 

8.00E-01 4.96E-02 7.63E-Ol 8.13E-Ol 

9.00E-01 4.98E-02 7.19E-01 7.69E-Ol 

1.00E+00 4.99E-02 6.74E-01 7.24E-Ol 

2.00E+00 5.00E-02 3.05E-Ol 3.55E-Ol 

3.00E+00 5.00E-02 1.21E-01 1.71E-Ol 

4.00E+00 5.00E-02 4.60E-02 9.60E-02 

5.00E+00 5.00E-02 1.71E-02 6.71E-02 

6.00E+00 5.00E-02 6.34E-03 5.63E-02 

7.00E+00 5.00E-02 2.34E-03 5.23E-02 

8.00E+00 5.00E-02 8.61E-04 5.08E-02 

9.00E+00 5.00E-02 3.17E-04 5.03E-02 

1.00E+01 5.00E-02 1.17E-04 5.01E-02 

2.00E+Ol 4.99E..;02 O.OOE+OO 4.99E-02 

3.00E+Ol 4.99E-02 O.OOE+OO 4.99E-02 

4.00E+01 4.98E-02 O.OOE+OO 4.98E-02 

5.00E+Ol 4.98E-02 O.OOE+OO 4.98E-02 

6.00E+Ol 4.98E-02 O.OOE+OO 4.98E-02 

7.00E+Ol 4.97E-02 O.OOE+OO 4.97E-02 

8.00E+01 4.97E-02 O.OOE+OO 4.97E-02 

9.00E+Ol 4.97E-02 O.OOE+OO 4.97E-02 

1.00E+02 4.96E-02 O.OOE+OO 4.96E-02 

2.00E+02 4.92E-02 O.OOE+OO 4.92E-02 

3.00E+02 4.89E-02 O.OOE+OO 4.89E-02 

4.·00E+02 4.85E-02 O.OOE+OO 4.85E-02 

5.00E+02 4.81E-02 O.OOE+OO 4.81E-02 

6.00E+02 4.78E-02 O.OOE+OO 4.78E-02 

7.00E+02 4.74E-02 O.OOE+OO 4.74E-02 

8.00E+02 4.71E-02 O.OOE+OO 4.71E-02 

9.00E+02 4.67E-02 O.OOE+OO 4.67E-02 ... 1.00E+03 4.63E-02 O.OOE+OO 4.63E-02 

2.00E+03 4.30E-02 O.OOE+OO 4.30E-02 

3.00E+03 3.98E-02 O.OOE+OO 3.98E-02 

4.00E+03 3.69E-02 O.OOE+OO 3.69E-02 

5.00E+03 3.42E-02 O.OOE+OO 3.42E-02 

7.00E+03 2.94E-02 O.OOE+OO 2.94E-02 

8.00E+03 2.72E-02 O.OOE+OO 2.72E-02 

9.00E+03 2.52E-02 O.OOE+OO 2.52E-02 

1.00E+04 2.34E-02 O.OOE+OO 2.34E-02 

2.00E+04 1.09E-02 O.OOE+OO 1.09E-02 

B-575 
INGESTION £1= 5.00E-02 STABLE CADMIUM 112 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 4.90E-08 6.06E-04 

2.00E-Ol 2.30E-07 5.83E-03 

3.00E-Ol S.02E-07 1.90E-02 

4.00E-Ol 8.25E-07 4.07E-02 

S.OOE-Ol 1.17E-06 6.99E-02 

6.00E-Ol 1.54E-06 I.05E-OI 

7.00E-Ol 1.9lE-06 1.4SE-OI 

8.00E-Ol 2.28E-06 1.87E-Ol 

9.00E-Ol 2.66E-06 2.31E-Ol 

1.00E+OO 3.04E-06 3.04E-06 2.76E-OI 2.76E-Ol 

2.00E+OO 3.80E-06 6.84E-06 3.69E-Ol 6.45E-Ol 

3.00E+OO 3.80E-06 I.06E-05 1.84E-Ol 8.29E-Ol 

4.00E+OO 3.80E-06 1.44E-05 7.52E-02 9.04E-OI 

5.00E+OO 3.80E-06 1.82E-05 2.89E-02 9.33E-Ol 

6.00E+OO 3.80E-06 2.20E-05 I.08E-02 9.44E-Ol 

7.00E+OO 3.80E-06 2.58E-05 4.00E-03 9.48E-Ol 

8.00E+OO 3.80E-06 2.96E-05 1.48E-03 9.49E-Ol 

9.00E+OO 3.80E-06 3.34E-05 5.44E-04 9.50E-OI 

1.00E+Ol 3. 79E-06 3.72E-OS 2.00E-04 9.50E-Ol 

2.00E+OI 3.79E-06 7.5IE-05 O.OOE+OO 9.50E-Ol 

3.00E+OI 3.79E-06 1.13E-04 O.OOE+OO 9.50E-OI 

4.00E+OI 3.79E-06 1.5IE-04 O.OOE+OO 9.50E-OI 

5.00E+OI 3.78E-06 1.89E-04 O.OOE+OO 9.50E-OI 

7.00E+OI 3.78E-06 2.64E-04 O.OOE+OO 9.50E-Ol 

8.00E+Ol 3. 77E-06 3.02E-04 O.OOE+OO 9.50E-Ol 

9.00E+OI 3.77E-06 3.40E-04 O.OOE+OO 9.50E-OI 

1.OOE+02 3.77E-06 3.78E-04 O.OOE+OO 9.50E-OI 

2.00E+02 3.74E-06 7.53E-04 O.OOE+OO 9.50E-OI 

3.00E+02 3.7IE-06 1.13E-03 O.OOE+OO 9.50E-OI 

4.00E+02 3.68E-06 1.50E-03 O.OOE+OO 9.50E-Ol 

5.00E+02 3.66E-06 1.86E-03 O.OOE+OO 9.50E-Ol 

7.00E+02 3.60E-06 2.59E-03 O.OOE+OO 9.50E-Ol 

8.00E+02 3.57E-06 2.95E-03 O.OOE+OO 9.50E-OI 

9.00E+02 3. 55E-06 3.30E-03 O.OOE+OO 9.50E-Ol 

l.OOE+03 3.52E-06 3.66E-03 O.OOE+OO 9.50E-Ol 

2.00E+03 3.26E-06 7.05E-03 O.OOE+OO 9.50E-Ol 

3.00E+03 3.02E-06 l.02E-02 O.OOE+OO 9.50E-Ol 

4.00E+03 2.80E-06 1.3lE-02 O.OOE+OO 9.50E-Ol 

5.00E+03 2.60E-06 1.58E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 2.23E-06 2.06E-02 O.OOE+OO 9.50E-Ol 

8.00E+03 2.07E-06 2.28E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 1.92E-06 2.48E-02 O.OOE+OO 9.50E-Ol 

l.OOE+04 1.78E-06 2.66E-02 O.OOE+OO 9.50E-Ol 

2.00E+04 8.3lE-07 3.9lE-02 O.OOE+OO 9.50E-Ol 

B-576 
INGESTION f1= 2.00E-02 STABLE TIN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5. 74E-03 9.93E-01 9. 99E-Ol 

2.00E-01 1.07E-02 9.82E-Ol 9.93E-01 

3.00E-Ol 1.29E-02 9. 65E-Ol 9.78E-Ol 

4.00E-Ol 1. 35E-02 9.41E-Ol 9.55E-01 

5.00E-01 1.33E-02 9.10E-Ol 9.23E-Ol 

6.00E-Ol 1. 28E-02 8. 74E-01 8.86E-01 

7.00E-01 1.23E-02 8.33E-01 8.45E-Ol 

8.00E-01 1.17E-02 7.89E-Ol 8.0lE-01 

9.00E-01 1. 13E-02 7.44E-01 7. 55E-Ol 

1.00E+00 1.09E-02 6.98E-Ol 7.09E-Ol 

2.00E+00 9.43E-03 3. 16E-Ol 3.26E-01 

3.00E+00 9.06E-03 1.26E-Ol 1.35E-01 

4.00E+00 8.80E-03 4.77E-02 5.65E-02 

5.00E+00 8.57E-03 1. 78E-02 2. 64E-02 

6.00E+00 8.38E-03 6. 58E-03 1.50E-02 

7.00E+00 8.20E-03 2.43E-03 1.06E-02 

8.00E+00 8.05E-03 8. 94E:"'04 8.94E-03 

9.00E+00 7.91E-03 3. 29E-04 8.24E-03 

1.00E+Ol 7. 79E-03 1.21E-04 7.91E-03 

2.00E+Ol 7.02E-03 O.OOE+OO 7.02E-03 

3.00E+Ol 6. 59E-03 O.OOE+OO 6.59E-03 

4.00E+Ol 6.27E-03 O.OOE+OO 6.27E-03 

5.00E+Ol 6.01E-03 O.OOE+OO 6.01E-03 

6.00E+Ol 5. 79E-03 O.OOE+OO 5. 79E-03 

7.00E+Ol 5.61E-03 O.OOE+OO 5.61E-03 

8.00E+Ol 5.44E-03 O.OOE+OO 5.44E-03 

9.00E+01 5.30E-03 O.OOE+OO 5.30E-03 

1.00E+02 5. 17E-03 O.OOE+OO 5. 17E-03 

2.00E+02 4.25E~03 O.OOE+OO 4. 25E-03 

3.00E+02 3. 57E-03 O.OOE+OO 3.57E-03 

4.00E+02 3.00E-03 O.OOE+OO 3.00E-03 

5.00E+02 2. 52E-03 O.OOE+OO 2. 52E-03 

6.00E+02 2. 12E-03 O.OOE+OO 2. 12E-03 

7.00E+02 1. 78E-03 O.OOE+OO 1. 78E-03 

8.00E+02 1.50E-03 O.OOE+OO 1.50E-03 

9.00E+02 1. 26E-03 O.OOE+OO 1. 26E-03 

1.00E+03 1.06E-03 O.OOE+OO 1.06E-03 

2.00E+03 1. 88E-04 O.OOE+OO 1.88E-04 

3.00E+03 3. 32E-05 O.OOE+OO 3.32E-05 

4.00E+03 5. 87E-06 O.OOE+OO 5.87E-06 

5.00E+03 1.04E-06 O.OOE+OO 1.04£-06 

6.00E+03 1. 84E-07 O.OOE+OO 1.84E-07 

7.00E+03 3.25E-08 O.OOE+OO 3.25E-08 

Jl~.1---
INGESTION f1= 2.00&-02 STABLE TIN 119 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3. 28E-04 6.08E-04 

2.00E-Ol 1.42E-03 5. 88E-03 

3.00E-Ol 2. 83E-03 1. 92E-02 

4.00E-OI 4. 23E-03 4.l3E-02 

S.OOE-OI 5. 47E-03 7.llE-02 

6.00E-OI 6.S2E-03 I.07E-OI 

7.00E-OI 7.38E-03 I.48E-Ol 

8.00E-OI 8.07E-03 I.9lE-OI 

9.00E-OI 8.6IE-03 2.36E-Ol 

1.OOE+OO 9.04E-03 9.04E-03 2. 82E-OI 2. 82E-Ol 

2.00E+OO 1. 53E-03 1.06E-02 3. 82E-Ol 6. 64E-OI 

3.00E+OO 3.72E-04 1.09E-02 1.90E-Ol 8.S4E-OI 

4.00E+OO 2. 62E-04 1.I2E-02 7.80E-02 9.32E-OI 

S.OOE+OO 2. 25E-04 I.14E-02 2. 99E-02 9. 62E-Ol 

6.00E+OO 1. 97E-04 1.I6E-02 1.I2E-02 9.73E-Ol 

7.00E+OO I.73E-04 1.18E-02 4.lSE-03 9.78E-OI 

8.00E+OO 1. S4E-04 I.20E-02 1. 53E-03 9.79E-Ol 

9.00E+OO 1. 37E-04 1.2IE-02 S.65E-04 9.80E-Ol 

I.OOE+Ol 1.22E-04 1. 22E-02 2.08E-04 9.80E-Ol 

2.00E+Ol 5. 48E-05 I.30E-02 O.OOE+OO 9.80E-Ol 

3.00E+Ol 3. 67E-05 1.34E-02 O.OOE+OO 9.80E-Ol 

4.00E+Ol 2. 87E-OS 1. 37E-02 O.OOE+OO 9.80E-Ol 

S.OOE+Ol 2. 38E-05 1.40E-02 O.OOE+OO 9.80E-Ol 

6.00E+Ol 2.0lE-05 1.42E-02 O.OOE+OO 9.80E-Ol 

7.00E+Ol 1.73E-05 1.44E-02 O.OOE+OO 9.80E-Ol 

8.00E+Ol 1.S2E-05 1.46E-02 O.OOE+OO 9.80E-Ol 

9.00E+Ol 1.36E-05 1.47E-02 O.OOE+OO 9.80E-Ol 

1.OOE+02 l.23E-OS I.48E-02 O.OOE+OO 9.80E-OI 

2.00E+02 7. 58E-06 I.57E-02 O.OOE+OO 9.80E-OI 

3.00E+02 6.20E-06 l.64E-02 O.OOE+OO 9.80E-OI 

4.00E+02 5.2IE-06 l.70E-02 O.OOE+OO 9.80E-OI 

5.00E+02 4. 38E-06 l.75E-02 O.OOE+OO 9.80E-Ol 

6.00E+02 3. 68E-06 I.79E-02 O.OOE+OO 9.80E-Ol 

7.00E+02 3.l0E-06 l.82E-02 O.OOE+OO 9.80E-Ol ... .. ~ 8.00E+02 2.60E-06 l.8SE-02 O.OOE+OO 9.80E-Ol 

9.00E+02 2.l9E-06 1. 87E-02 O.OOE+OO 9.80E-Ol 

I.OOE+03 I.84E-06 l.89E-02 O.OOE+OO 9.80E-Ol 

2.00E+03 3.2SE-07 1. 98E-02 O.OOE+OO 9.80E-OI 

3.00E+03 S.76E-08 2.00E-02 O.OOE+OO 9.80E-OI 

4.00E+03 I.02E-08 2.00E-02 O.OOE+OO 9.80E-OI 

B-578 
INGESTION £1= 2.00&-01 STABLE TELLUlUUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 6. 95E-02 9.29E-Ol 9. 98E-Ol 

2.00E-01 I.30E-Ol 8.59E-OI 9.89E-OI 

3.00E-OI 1.58E-OI 8.13E-01 9.70E-OI 

4.00E-01 I. 67E-OI 7. 77E-01 9. 44E-OI 

5.00E-Ol 1.68E-OI 7.43E-Ol 9.llE-0! 

6.00E-Ol I. 66E-OI 7.08E-OI 8. 74E-OI 

7.00E-OI I.6IE-Ol 6.12E-Ol 8. 34E-Ol 

8.00E-OI I.57E-OI 6. 35E-Ol 7. 92E-Ol 

9.00E-Ol 1. 52E-Ol 5.97E-Ol 7. 49E-Ol 

1.00E+00 1.48E-Ol 5. 59E-Ol 7.07E-Ol 

2.00E+00 1.18E-01 2.51E-Ol 3. 68E-Ol 

3.00E+00 1.04E-OI 9. 93E-02 2.03E-Ol 

4.00E+00 9. 74E-02 3. 76E-02 1. 35E-Ol 

5.00E+00 9. 38E-02 1.40E-02 1.08E-Ol 

6.00E+00 9. 15E-02 5. 19E-03 9. 67E-02 

7.00E+00 8. 97E-02 1.91E-03 9. 16E-02 

8.00E+00 8. 82E-02 7.04E-04 8. 89E-02 

9.00E+00 8. 68E-02 2. 59E-04 8.71E-02 

1.00E+Ol 8.55E-02 9.54E-'05 8.56E-02 

2.00E+Ol 7.50E-02 O.OOE+OO 7.50E-02 

3.00E+Ol 6.76E-02 O.OOE+OO 6.76E-02 

4.00E+Ol 6.23E-02 O.OOE+OO 6. 23E-02 

5.00E+Ol 5. 86E-02 O.OOE+OO 5. 86E-02 

6.00E+Ol 5. 59E-02 O.OOE+OO 5. 59E-02 

7.00E+Ol 5.40E-02 O.OOE+OO 5.40E-02 

8.00E+Ol 5. 26E-02 O.OOE+OO 5. 26E-02 I 9.00E+Ol 5.16E-02 O.OOE+OO 5. 16E-02 I 

1.00E+02 5.09E-02 O.OOE+OO 5.09E-02 

2.00E+02 4. 87E-02 O.OOE+OO 4. 87E-02 

3.00E+02 4.80E-02 O.OOE+OO 4.80E-02 

4.00E+02 4. 73E-02 O.OOE+OO 4. 73E-02 

5.00E+02 4. 67E-02 O.OOE+OO 4. 67E-02 

6.00E+02 4.60E-02 O.OOE+OO 4.60E-02 

7.00E+02 4. 54E-02 O.OOE+OO 4. 54E-02 

8.00E+02 4 •. 48E-02 O.OOE+OO 4. 48E-02 

9.00E+02 4.41E-02 O.OOE+OO 4.41E-02 

1.00E+03 4. 35E-02 O.OOE+OO 4. 35E-02 

2.00E+03 3. 79E-02 O.OOE+OO 3. 79E-02 

3.00E+03 3.30E-02 O.OOE+OO 3.30E-02 

4.00E+03 2. 87E-02 O.OOE+OO 2. 87E-02 

5.00E+03 2.50E-02 O.OOE+OO 2.50E-02 

7.00E+03 1.90E-02 O.OOE+OO 1.90E-02 

8.00E+03 1. 65E-02 O.OOE+OO 1.65E-02 

9.00E+03 1. 44E-02 O.OOE+OO 1.44E-02 

1.00E+04 1.25E-02 O.OOE+OO 1. 25E-02 

2.00E+04 3. 13E-03 O.OOE+OO 3. 13E-03 

B-579 
I.NGESTION fl= 2.00B-ol STABLE TELLURIUM 128 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE 

24-HOUR ACCUMULATED 24-HOUR 

DAYS URINE URINE FECES 

1.OOE-Ol 9. 63E-04 9.l3E-04 

2.00E-Ol . 4. 28E-03 7.0lE-03 

3.00E-OI 8.8SE-03 2.08E-02 

4.00E-Ol 1.38E-02 4. 22E-02 

S.OOE-Ol 1. 87E-02 7.00E-02 

6.00E-Ol 2. 34E-02 1.03E-Ol 

7.00E-OI 2. 78E-02 1.39E-Ol 

8.00E-Ol 3.19E-02 1. 76E-OI 

9.00E-OI 3. S6E-02 2. ISE-OI 

I.OOE+OO 3.9IE-02 3.9IE-02 2.S4E-OI 2.S4E-OI 

2.00E+OO 2. 27E-02 6.18E-02 3.16E-Ol S.70E-Ol 

3.00E+OO 1.02E-02 7.20E-02 I.SSE-OI 7.2SE-OI 

4.00E+OO 4.9SE-03 7.69E-02 6. 33E-02 7.88E-OI 

S.OOE+OO 2.72E-03 7. 96E-02 2.4SE-02 8.l3E-OI 

6.00E+OO 1. 76E-03 8.l4E-02 9.42E-03 8. 22E-Ol 

7.00E+OO 1. 33E-03 8.27E-02 3. 72E-03 8.26E-OI 

8.00E+OO I.13E-03 8. 39E-02 1. S9E-03 8.27E-Ol 

9.00E+OO 1.03E-03 8. 49E-02 7. 88E-04 8. 28E-Ol 

I.OOE+Ol 9. 67E-04 8.S9E-02 4.86E-04 8.29E-OI 

2.00E+Ol 6.70E-04 9. 37E-02 2. 23E-04 8.3lE-Ol 

3.00E+Ol 4. 76E-04 9.93E-02 1. S9E-04 8. 33E-Ol 

4.00E+Ol 3. 38E-04 I.03E-OI 1.13E-04 8.34E-OI 

S.OOE+Ol 2.40E-04 1.06E-OI 8. OlE-OS 8.3SE-0l 

6.00E+OI 1.72E-04 1.08E-OI S.72E-OS 8. 36E-Ol 

7.00E+Ol 1. 23E-04 I.IOE-Ol 4.09E-OS 8. 37E-0l 

8.00E+OI 8. 83E-OS I.llE-Ol 2. 94E-OS 8. 37E-Ol 

9.00E+OI 6.40E-OS 1.llE-OI 2.l3E-OS 8.37E-Ol 

I.OOE+02 4. 67E-OS 1.I2E-Ol I.S6E-OS 8. 37E-Ol 

2.00E+02 6. 36E-06 I.13E-Ol 2.12E-06 8.38E-Ol 

3.00E+02 S.03E-06 I.I4E-Ol 1. 68E-06 8.38E-OI 

4.00E+02 4. 92E-06 1. ISE-OI 1.64E-06 8.38E-OI 

S.OOE+02 4.8SE-06 1. ISE-Ol l.62E-06 8. 38E-OI 

6.00E+02 4. 78E-06 I.ISE-OI 1. S9E-06 8.38E-OI 

7.00E+02 4.72E-06. 1.I6E-OI I.S7E-06 8. 39E-OI 

8.00E+02 4.6SE-06 I.16E-OI 1. SSE-06 8. 39E-OI 

9.00E+02 4.S9E-06 I.17E-Ol I.S3E-06 8. 39E-OI 

I.OOE+03 4.S3E-06 1.17E-OI 1. SIE-06 8.39E-OI 

2.00E+03 3. 94E-06 1. 22E-OI I.3IE-06 8.4IE-OI 

3.00E+03 3. 43E-06 1.2SE-0l I.14E-06 8. 42E-OI 

4.00E+03 2. 99E-06 1. 28E-OI 9.9SE-07 8. 43E-OI 

S.OOE+03 2.60E-06 1.3IE-OI 8.66E-07 8. 44E-OI 

7.00E+03 1. 97E-06 1.36E-OI 6. 57E-07 8. 45E-Ol 

8.00E+03 I.72E-06 I.38E-OI 5.72E-07 8. 46E-OI 

9.00E+03 1.49E-06 I.39E-OI 4. 98E-07 8.46E-OI 

I.OOE+04 I.30E-06 1.41E-OI 4 .. 33E-07 8. 47E-Ol 

2.00E+04 3.2SE-07 1. 48E-OI I.08E-07 8.49E-OI 

B-S80 
IRGESTION f 1 = 1.00E+OO BALFLIFE= 1.30E+Ol DAYS IODINE 126 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI 24-HOUR TOTAL 

DAYS ORGANS THYROID TRACT URINE BODY 

1.OOE-Ol 7.97E-Ol 4. 62E-02 9.02E-02 8.87E-Ol 

2.00E-Ol 7.38E-Ol 1.04E-Ol 8.l4E-03 7.46E-Ol 

3.00E-Ol 6. 34E-Ol 1.50E-Ol 7.36E-04 6. 34E-Ol 

4.00E-Ol S.49E-Ol 1. 84E-Ol 6. 72E-OS 5.49E-Ol 

S.OOE-Ol 4.8SE-Ol 2.09E-Ol 6. 83E-06 4.8SE-OI 

6.00E-Ol 4.36E-Ol 2. 28E-Ol 1. 34E-06 4.36E-Ol 

7.00E-Ol 3.99E-0l 2.4lE-0l 7.99E-07 3. 99E-Ol 

8.00E-Ol 3.70E-Ol 2.SlE-Ol 7.0SE-07 3.70E-Ol 

9.00E-Ol 3. 48E-Ol 2.SSE-Ol 6.SlE-07 3.4SE-Ol 

1.OOE+OO 3.3lE-Ol 2. 63E-Ol 6.02E-07 S.98E-Ol 3.3lE-Ol 

2.00E+OO 2. 72E-Ol 2.6SE-Ol 2.4SE-07 4.06E-02 2.72E-Ol 

3.00E+OO 2.S6E-Ol 2.S6E-Ol 9. 23E-OS 2.S7E-03 2.S6E-Ol 

4.00E+OO 2. 42E-0l 2. 42E-Ol 3.30E-OS 3.6SE-04 2.42E-Ol 

S.OOE+OO 2. 29E-Ol 2. 29E-Ol 1.17E-08 2.S6E-04 2. 29E-Ol 

6.00E+OO 2.l7E-Ol 2.l7E-Ol O.OOE+OO 3.2lE-04 2.l7E-Ol 

7.00E-IrOO 2.0SE-Ol 2.0SE-Ol O.OOE+OO 3. 55E-04 2.0SE-Ol 

S.OOE+OO 1. 94E-Ol 1. 94E-Ol O.OOE+OO 3.8lE-04 1. 94E-Ol 

9.00E+OO 1. 84E-Ol 1. 84E-Ol O.OOE+OO 4.02E-04 1. 84E-Ol 

1.OOE+Ol 1.74E-Ol 1.74E-0l O.OOE+OO 4.l5E-04 1. 74E-Ol 

2.00E+Ol 9.8SE-02 9. 85E-02 O.OOE+OO 3.SSE-04 9.8SE-02 

:.s.OOE+Ol S.S2E-02 S.S2E-02 O.OOE+OO 2.63E-04 S.S2E-02 

4.00E+Ol 3.08E-02 3.08E-02 O.OOE+OO 1.6lE-04 3.0SE-02' 

5.00E+Ol 1.7lE-02 1.7lE-02 O.OOE+OO 9.4lE-OS 1.71E-02 

6.00E+Ol 9.46E-03 9.46E-03 O.OOE+OO ' S.36E-05 9.46E-03 

7.00E+Ol 5. 23E-03 5. 23E-03 O.OOE+OO 3.02E-05 5. 23E-03 

8.00E+Ol 2.S9E-03 2. 89E-03 O.OOE+OO 1.68E-05 2.S9E-03 

9.00E+Ol 1.60E-03 1.60E-03 O.OOE+OO 9. 34E-06 1.60E-03 

1.00E+02 8. 83E-04 8. 83E-04 O.OOE+OO S.18E-06 8. 83E-04 

2.00E+02 2. 33E-06 2. 33E-06 O.OOE+OO 1.3SE-08 2. 33E-06 

B-58l 
INGESTION fl== 1.00£+00 BALFLIFE== 1.30£+01 DAYS IODINE 126 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------~-----~---------------------------------- SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.OSE-OI 4. IOE-09 

2.00E-OI 2. 43E-OI 2.0SE-OS 

3.00E-Ol 3.S0E-Ol 4.S4E-OS 

4.00E-OI 4. 29E-ol 8. 39E-OS 

S.OOE-Ol 4. S9E-Ol 1.24E-07 

6.00E-Ol S.33E-Ol 1.6SE-07 

7.00E-Ol S.6SE-Ol 2. 13E-07 

S.OOE-Ol S.8SE-Ol 2.SSE-07 

9.00E-Ol 6.0SE-OI 3.03E-07 

1.00E+OO 6. 17E-Ol 6. 17E-Ol 3. 46E-07 3. 46E-07 

2.00E+OO 4. 19E-02 6. 26E-Ol 3.23E-07 6. SIE-07 

3.00E+OO 2.6SE-03 S.97E-Ol 1. 43E-07 7.60E-07 

4.00E+OO 3. 79E-04 S.66E-Ol S.4SE-OB 7.7SE-07 

S.OOE+OO 2.9SE-04 S.37E-Ol 1. 97E-OB 7. 54E-07 

6.00E+OO 3. 31E-04 5.09E-OI O.OOE+OO 7.22E-07 

7.00E+OO 3. 66E-04 4.S3E-ol O.OOE+OO 6.S7E-07 

S.OOE+OO 3. 93E-04 4.S9E-Ol O.OOE+OO 6. S2E-07 

9.00E+OO 4. 14E-04 4.3SE-ol O.OOE+OO 6. 19E-07 

1.00E+OI 4.2SE-04 4.13E-Ol O.OOE+OO S.S7E-07 

2.00E+Ol 3. 97E-04 2. 46E-Ol O.OOE+OO 3. 44E-07 

3.00E+Ol 2.71E-04 1.47E-Ol O.OOE+OO 2.02E-07 

4.00E+Ol 1. 66E-04 B.77E-02 O.OOE+OO 1. 19E-07 

S.OOE+Ol 9.70E-OS S.2SE-02 O.OOE+OO 6.9SE-OS 

6.00E+Ol 5.S3E-05 3. 13E-02 O.OOE+OO 4.08E-OB 

7.00E+OI 3. lIE-OS I.S7E-02 O.OOE+OO 2. 39E-08 

8.00E+Ol 1.73E-OS 1. 12E-02 O.OOE+OO 1.40E-oB 

9.00E+Ol 9. 63E-06 6.64E-03 O.OOE+OO S.24E-09 

I.OOE+02 S.34E-06 3.9SE-03 O.OOE+OO 4. 83E-09 

2.00E+02 1.42E-OB 2.lOE-05 O.OOE+OO 2.34E-ll 

B-5B2 
INGESTION f 1= 1.00£+00 STABLE IODINE 127 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------~----------------------------------- SYSTEMIC GI 24-HOUR TOTAL 

DAYS ORGANS THYROID TRACT URINE BODY 

1.00E-01 8.01E-01 4. 65E-02 9.07E-02 8.92E-01 

2.00E-Ol 7.46E-01 1.05E-01 8. 23E-03 7.54E-Ol 

3.00E-01 6. 44E-Ol 1.52E-01 7.48E-04 6.45E-01 

4.00£-01 5.61E-01 1. 88E-Ol 6.86E-05 5.61E-Ol 

5.00E-01 4. 98E-01 2. 15E-Ol 7.02E-06 4. 98E-Ol 

6.00E-Ol 4.50E-01 2.35E-01 1. 38E-06 4.50E-Ol 

7.00E-Ol 4.14E-Ol 2.50E-01 8.30E-07 4. 14E-01 

8.00E-01 3. 86E-01 2. 62E-Ol 7. 35E-07 3. 86E-01 

9.00E-01 3.65E-01 2.71E-01 6. 83E-07 3. 65E-01 

1.00E+00 3.50E-01 2.77E-01 6. 35E-07 6.31E-01 3.50E-01 

2.00E+00 3.03E-Ol 2.95E-01 2.76E-07 4. 52E-02 3.03E-01 

3.00E+00 3.00E-Ol 2. 93E-Ol 1.08E-07 3.02E-03 3.00E-01 

4.00E+00 2. 99E-01 2. 91E-01 4.09E-08 4.55E-04 2. 99E-01 

5.00E+00 2. 99E-01 2.89E-Ol 1. 52E-08 3. 73E-04 2.99E-01 

6.00E+00 2.99E-01 2.86E-01 O.OOE+OO 4.42E-04 2.99E-Ol 

7.00E+00 2. 98E-01 2. 84E-01 O.OOE+OO 5. 15E-04 2. 98E-01 

8.00E+00 2. 97E-01 2.82E-01 O.OOE+OO 5. 84E-04 2.97E-01 

9.00E+00 2.97E-01 2.80E-Ol O.OOE+OO 6. 48E-04 2.97E-Ol 

1.00E+Ol 2.96E-01 2.78E-Ol O.OOE+OO 7.08E-04 2. 96E-01 

2.00E+Ol 2.86E-01 2. 58E-Ol O.OOE+OO 1. 12E-03 2. 86E-01 

3.00E+01 2. 74E-01 2.41E-01 O.OOE+OO 1.30E-03 2.74E-Ol 

4.00E+01 2.60E-01 2. 26E-01 O.OOE+OO 1. 36E-03 2.60E-01 

5.00E+Ol 2.46E-01 2. 12E-01 O.OOE+OO 1.35E-03 2.46E-01 

6.00E+01 2.32E-01 1.99E-01 O.OOE+OO 1.31E-03 2.32E-01 

7.00E+01 2.19E-Ol 1.88E-Ol O.OOE+OO 1.26E-03 2. 19E-01 

8.00E+01 2.06E-01 1. 76E-Ol O.OOE+OO 1.19E-03 2.06E-Ol 

9.00E+Ol 1.94E-01 1.66E-01 O.OOE+OO 1. 13E-03 1. 94E-01 

1.00E+02 1.83E-01 1. 56E-01 O.OOE+OO 1.07E-03 1.83E-Ol 

2.00E+02 9.98E-02 8. 53E-02 O.OOE+OO 5. 88E-04 9. 98E-02 

3.00E+02 5.45E-02 4. 66E-02 O.OOE+OO 3. 21E-04 5.45E-02 

4.00E+02 2.98E-02 2.54E-02 O.OOE+OO 1.76E-04 2. 98E-02 

5.00E+02 1.63E-02 1.39E-02 O.OOE+OO 9. 56E-05 1. 63E-02 

6.00E+02 8. 88E-03 7.59E-03 O.OOE+OO 5. 23E-05 8. 88E-03 

7.00E+02 4. 85E-03 4. 14E-03 O.OOE+OO 2. 85E-05 4. 85E-03 

8.00E+02 2. 65E-:-03 2. 26E-03 O.OOE+OO 1.56E-05 2. 65E-03 

9.00E+02 1.45E-03 1. 24E-03 O.OOE+OO 8.51E-06 1.45E-03 

1.00E+03 7. 89E-04 6. 75E-04 O.OOE+OO 4.65E-06 7. 89E-04 

2.00E+03 1.86E-06 1.59E-06 O.OOE+OO 1.lOE-08 1. 86E-06 

B-583 
INGESTION £1= 1.00£+00 STABLE IODINE 127 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACC ll1ULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0l 1.OBE-Ol 4.l2E-09 

2.00E-Ol 2.46E-Ol 2.lOE-OB 

3.00E-Ol 3.SSE-Ol 4.92E-OB 

4.00E-Ol 4. 39E-Ol B.S7E-08 

S.OOE-Ol 5.02E-Ol 1.2BE-07 

6.00E-Ol 5.S0E-Ol 1.73E-07 

7.00E-Ol S.86E-OI 2.21E-07 

8.00E-OI 6. 14E-OI 2. 69E-07 

9.00E-Ol 6.3SE-0l 3.17E-07 

1.OOE+OO 6.50E-Ol 6.S0E-Ol 3.6SE-07 3.6SE-07 

2.00E+OO 4.66E-02 6.97E-Ol 3.S9E-07 7.24E-07 

3.00E+OO 3.llE-03 7.00E-Ol 1. 68E-07 8. 92E-07 . 4. OOE+OO 4. 69E-04 7.0IE-Ol 6. 74E-OB 9.59E-07 

S.OOE+OO 3.8SE-04 7.0IE-Ol 2.S7E-OB 9. BSE-07 

6.00E+OO 4.S6E-04 7.0IE-Ol O.OOE+OO 9. 94E-07 

7.00E+OO S.3lE-04 7.02E-Ol O.OOE+OO 9.9BE-07 

8.00E+OO 6.02E-04 7.03E-Ol O.OOE+OO 9. 99E-07 

9.00E+OO 6.6BE-04 7.03E-Ol O.OOE+OO 1.OOE-06 

1.OOE+Ol 7.30E-04 7.04E-Ol O.OOE+OO 1.00E-06 

2.00E+Ol l.lSE-03 7. 14E-Ol O.OOE+OO 1.00E-06 

3.00E+Ol 1.34E-03 7. 26E-OI O.OOE+OO 1.OOE-06 

4.00E+Ol 1.40E-03 7.40E-Ol O.OOE+OO 1.OOE-06 

S.OOE+Ol 1.39E-03 7.S4E-Ol O.OOE+OO I.OOE-06 

6. OOE+O 1 1.3SE-03 7.6BE-Ol O.OOE+OO 1.OOE-06 

7.00E+0l 1.30E-03 7.BlE-Ol O.OOE+OO 1.OOE-06 

8.00E+OI 1.2~n:-03 ·7.94E-Ol O.OOE+OO I.OOE-06 

9.00E+Ol 1.17E-03 8.06E-Ol O.OOE+OO 1.OOE-06 

1.00E+02 1.lOE-03 8.l7E-Ol O.OOE+OO 1.00E-06 

2.00E+02 6.06E-04 9.00E-Ol O.OOE+OO 1.00E-06 

3.00E+02 3.3lE-04 9.4SE-Ol O.OOE+OO 1.OOE-06 

4.00E+02 1.BIE-04 9.70E-Ol O.OOE+OO 1.00E-06 

S.OOE+02 9.B6E-OS 9.B4E-Ol O.OOE+OO 1.OOE-06 

6.00E+02 S.39E-OS 9.9lE-Ol O.OOE+OO 1.00E-06 

7.00E+02 2.94E-OS 9.9SE-Ol O.OOE+OO 1.OOE-06 

8.00E+02 1.61E-OS 9.97E-Ol O.OOE+OO 1.00E-06 

9.00E+02 B.77E-06 9.99E-Ol O.OOE+OO I.OOE-06 

1.OOE+03 4. 79E-06 9.99E-Ol O.OOE+OO 1.00E-06 

2.00E+03 1.l3E-08 1.00E+OO O.OOE+OO 1.00E-06 

B-S84 
INGESTION fl= 1.00E+<lO BALPLIFE= 5.73E+<l9 DAYS IODINE 129 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI 24-HOUR TOTAL 

DAYS ORGANS THYROID TRACT URINE BODY 

1.00E-01 8.0lE-01 4. 65E-02 9.07E-02 8. 92E-01 

2.00E-Ol 7.46E-Ol 1.05E-01 8. 23E-03 7.54E-Ol 

3.00E-01 6. 44E-Ol 1. 52E-01 7. 48E-04 6. 45E-Ol 

4.00E-01 5.61E-01 1.88E-Ol 6. 86E-05 5. 61E-01 

5.00E-01 4. 98E-01 2. 15E-01 7.02E-06 4.98E-Ol 

6.00E-01 4.50E-Ol 2. 35E-01 1. 38E-06 4.50E-Ol 

7.00E-Ol 4. 14E-01 2.50E-Ol 8.30E-07 4. 14E-Ol 

8.00E-Ol 3.86E-Ol 2. 62E-01 7.35E-07 3. 86E-Ol 

9.00E-Ol 3. 65E-Ol 2.71E-01 6. 83E-07 3. 65E-Ol 

1.00E+00 3.50E-Ol 2.77E-01 6. 35E-07 6.31E-Ol 3.50E-Ol 

2.00E+00 3.03E-01 2. 95E-01 2. 76E-07 4. 52E-02 3.03E-01 

3.00E+00 3.00E-01 2. 93E-01 1.08E-07 3.02E-02 3.00E-Ol 

4.00E+00 2.99E-01 2.91E-01 4.09E-08 4.55E-04 2. 99E-Ol 

5.00E+00 2.99E-Ol 2. 89E-Ol 1. 52E-08 3. 73E-04 2. 99E-Ol 

6.00E+00 2. 99E-01 2.86E-01 O.OOE+oo 4.42E-04 2. 99E-Ol 

7.00E+00 2. 98E-01 2. 84E-Ol O.OOE+OO 5. 15E-04 2. 98E-Ol 

8.00E+00 2.97E-01 2. 82E-Ol O.OOE+OO 5.84E-04 2.97E-01 

9.00E+00 2.97E-Ol 2.80E-Ol O.OOE+OO 6.48E-04 2. 97E-01 

1.00E+01 2.96E-Ol 2. 78E-01 O.OOE+oo 7.08E-04 2.96E-Ol 

2.00E+Ol 2.86E-01 2.58E-Ol O.OOE+OO 1.12E-03 2.86E-01 

3.00E+Ol 2. 74E-Ol 2.41E-Ol O.OOE+OO 1.30E-03 2. 74E-Ol 

4.00E+Ol 2.60E-01 2.26E-01 O.OOE+OO 1. 36E-03 2.60E-Ol 

5.00E+01 2. 46E-01 2.12E-01 O.OOE+OO 1.35E-03 2. 46E-01 

6.00E+01 2. 32E-01 1. 99E-01 O.OOE+OO 1.31E-03 2. 32E-01 

7.00E+01 2.19E-01 1.88E-01 O.OOE+OO 1.26E-03 2. 19E-01 

8.00E+01 2.06E-Ol 1. 76E-Ol O.OOE+OO 1. 19E-03 2.06E-Ol 

9.00E+01 1.94E-01 1.66E-Ol O.OOE+OO 1.13E-03 1. 94E-Ol 

1.00E+02 1. 83E-01 1.56E-Ol O.OOE+OO 1.07E-03 1.83E-01 

2.00E+02 9. 98E-02 8.53E-02 O.OOE+OO 5. 88E-04 9. 98E-02 

3.00E+02 5. 45E-02 4. 66E-02 O.OOE+OO 3.21E-04 5. 45E-02 

4.00E+02 2.98E-02 2. 54E-02 O.OOE+oo 1.76E-04 2.98E-02 

5.00E+02 1. 63E-02 1.39E-02 O.OOE+OO 9. 56E-05 1. 63E-02 

6.00E+02 8.88E-03 7.59E-03 O.OOE+OO 5.23E-05 8. 88E-03 

7.00E+02 4. 85E-03 4. 14E-03 O.OOE+OO 2. 85E-05 4. 85E-03 

8.00E+02 2.65E-03 2.26E-03 O.OOE+oo 1. 56E-05 2. 65E-03 

9.00E+02 1.45E-03 1. 24E-03 O.OOE+OO 8.51E-06 1.45E-03 

, {" 1.00E+03 7. 89E-04 6. 75E-04 O.OOE+oo 4. 65E-06 7. 89E-04 

2.00E+03 1. 86E-06 1. 59E-06 O.OOE+OO l.lOE-08 1. 86E-06 

B-585 
INGESTION f 1'''' i.ooE+OO HALFLIFE= 5.73E+09 DAYS IODINE 129 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE 

SYSTEMIC NON-SYSTEMIC 

-------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.08E-01 4. 12E-09 

2.00E-01 2. 46E-Ol 2.lOE-08 

3.00E-01 3.55E-Ol 4. 92E-08 

4.00E-01 4. 39E-Ol 8. 57E-08 

5.00E-Ol 5.02E-Ol 1. 28E-07 

6.00E-Ol 5.50E-Ol 1. 73E-07 

7.00E-Ol 5. 86E-Ol 2. 21E-07 

8.00E-01 6. 14E-Ol 2. 69E-07 

9.00E-01 6.35E-Ol 3. 17E-07 

1.00E+00 6.50E-01 6.50E-Ol 3. 65E-07 3. 65E-07 

2.00E+00 4. 66E-02 6. 97E-01 3.59E-07 7. 24E-07 

3.00E+00 3. 11E-03 7.00E-01 1.68E-07 8. 92E-07 

4.00E+00 4. 69E-04 7.01E-01 6.74E-08 9.59E-07 

5.00E+00 3. 85E-04 7.01E-Ol 2. 57E-08 9. 85E-07 

6.00E+00 4. 56E-04 7.01E-Ol O.OOE+OO 9. 94E-07 

7.00E+00 5. 31E-04 7.02E-01 O.OOE+OO 9. 98E-07 

8.00E+00 6.02E-04 7.03E-01 O.OOE+OO 9. 99E-07 

9.00E+00 6. 68E-04 7.03E-01 O.OOE+OO 1.00E-06 

1.00E+Ol 7.30E-04 7.04E-01 O.OOE+OO 1.00E-06 

2.00E+Ol 1. 15E-03 7. 14E-Ol O.OOE+OO 1.00E-06 

3.00E+Ol 1 • .34E-03 7.26E-Ol O.OOE+OO 1.00E-06 

4.00E+01 1.40E-03 7.40E-01 O.OOE+OO 1.00E-06 

5.00E+01 1. 39E-03 7. 54E-01 O.OOE+OO 1.00E-06 

6.00E+Ol 1. 35E-03 7. 68E-01 O.OOE+OO 1.00E-06 

7.00E+01 1.30E-03 7.81E-01 O.OOE+OO 1.00E-06 

8.00E+Ol 1. 23E-03 7. 94E-01 O.OOE+OO 1.00E-06 

9.00E+Ol 1. 17E-03 8.06E-01 O.OOE+oo 1.00E-06 

1.00E+02 l.lOE-03 8. 17E-01 O.OOE+OO 1.00E-06 

2.00E+02 6.06E-04 9.00E-01 O.OOE+OO 1.00E-06 

3.00E+02 3. 31E-04 9.45E-01 O.OOE+OO 1.00E-06 

4.00E+02 1.81E-04 9.70E-Ol O.OOE+OO 1.00E-06 

5.00E+02 9. 86E-05 9. 84E-Ol O.OOE+OO 1.00E-06 

6.00E+02 5. 39E-05 9.91E-01 O.OOE+OO 1.00E-06 

7.00E+02 2. 94E-05 9. 95E-01 O.OOE+OO 1.00E-06 , , 8.00E+02 1. 61E-05 9. 97E-01 O.OOE+OO 1.00E-06 

9.00E+02 8.77E-06 9.99E-Ol O.OOE+OO 1.00E-06 

1.00E+03 4. 79E-06 9. 99E-01 O.OOE+OO 1.00E-06 

2.00E+03 1. 13E-08 1.00E+00 O.OOE+OO 1.00E-06 

B-586 
INGESTION fl= 1.00E+OO BALFLIFE= 8.04E+OO DAYS IODINE 131 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI 24-HOUR TOTAL 

DAYS ORGANS THYROID TRACT URINE BODY 

1.OOE-Ol 7. 94E-Ol 4.6lE-02 B.99E-02 B.B4E-Ol 

2.00E-Ol 7.33E-Ol 1.04E-Ol B.09E-03 7.4lE-Ol 

3.00E-Ol 6. 27E-Ol 1.48E-Ol 7. 28E-04 6.28E-Ol 

4.00E-Ol 5.42E-Ql 1.BlE-Ol 6. 63E-05 5.42E-Ol 

5.00E-Ol 4.77E-Ol 2.06E-Ol· 6. 72E-06 4.77E-Ol 

6.00E-Ol 4.27E-Ol 2.2~E-OI 1.3lE-06 4.27E-OI 

7.00E-OI 3.90E-Ol 2. ~6E-Ol 7.8IE-07 3.90E-Ol 

8.00E-Ol 3.6IE-Ol 2.44E-Ol 6.B6E-07 3.6lE-Ol 

9.00E-Ol 3.3BE-Ol 2.50E-OI 6. 32E-07 3.3BE-Ol 

1.OOE+OO 3.2lE-OI 2.S4E-Ol S.83E-07 S.79E-Ol 3.2IE-OI 

2.00E+OO 2. S5E-0l 2.48E-Ol 2. 32E-07 3. BOE-02 2.SSE-OI 

3.00E+OO 2. 32E-OI 2.27E-OI 8.36E-OB 2. 33E-03 2.32E-Ol 

4.00E+OO 2.l2E-OI 2.06E-OI 2.'90E-08 3. 22E-04 2.l2E-0l 

5.00E+OO 1. 94E-OI 1. 88E-OI O.OOE+OO 2;j43E-04 1. 94E-OI 

6.00E+OO 1. 78E-OI 1.71E-OI O.OOE+OO 2. 64E-04 1. 78E-Ol 

7.00E+OO 1.63E-OI 1.5SE-Ol O.OOE+OO 2.8IE-04 1.63E-Ol 

8.00E+OO 1.49E-OI 1.42E-Ol O.OOE+OO 2. 93E-04 1. 49E-Ol 

9.00E+OO 1. 37E-Ol 1.29E-OI O.OOE+OO 2. 99E-04 1.37E-OI 

1.OOE+Ol 1.2SE-Ol 1.17E-Ol O.OOE+OO, 2. 99E-04 1.25E-OI 

2.00E+Ol S.lOE-02 4.6lE-02 O.OOE+OO 2.00E-04 S.lOE-02 

3.00E+OI 2.06E-02 1.82E-02 O.OOE+OO 9.80E-OS 2.06E-02 

4.00E+Ol 8. 26E-03 7.2IE-03 O.OOE+OO 4. 32E-05 8. 26E-03 

S.OOE+OI 3.30E-03 2. 86E-03 O.OOE+OO 1.8lE-OS 3.30E-03 

6.00E+Ol 1.3IE-03 1.14E-03 O.OOE+OO 7.4SE-06 1.3IE-03 

7.00E+Ol S.23E-04 4. S2E-04 O.OOE+OO 3.02E-06 S.23E-04 

8.00E+Ol 2.08E-04 1.80E-04 O.OOE+OO 1.2lE-06 2.08E-04 

9.00E+OI 8.28E-OS 7.16E-OS O.OOE+OO 4. 86E-07 8. 28E-OS 

I.OOE+02 3. 29E-OS 2.8SE-OS O.OOE+OO 1. 93E-07 3. 29E-OS 

B-S87 
INGESTION f l= 1.00£+00 BALFLlFE- 8.04£+00 DAYS IODINE 131 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 1.07E-OI 4.09E-09 

2.00E-OI 2.42E-OI 2.07E-08 

3.00E-OI 3.46E-0l 4.80E-08 

4.00E-OI 4. 24E-OI 8. 28E-08 

5.00E-OI 4.8IE-0l 1. 22E-07 

6. OOE-O 1 5.22E-OI I. 65E-07 

7.00E-OI 5.52E-OI 2.08E-07 

8.00E-OI S.73E-OI 2.5IE-07 

9.00E-0l 5. 87E-OI 2. 94E-07 

I.OOE+OO 5. 97E-OI 5. 97E-OI 3. 34E-07 3. 34E-07 

2.00E+OO 3. 92E-02 5. 87E-OI 3.02E-07 6.09E-07 

3.00E+OO 2.40E-03 5.4IE-OI I.30E-07 6. 88E-07 

4.00E+OO 3.32E-04 4.96E-OI 4.77E-08 6. 79E-07 

5.00E+OO 2.S0E-04 4.5SE-OI 1. 67E-08 6.40E-07 

6.00E+OO 2.72E-04 4.18E-OI O.OOE+OO S.93E-07 

7.00E+OO 2.90E-04 3. 84E-OI O.OOE+OO 5. 46E-07 

8.00E+OO 3.02E-04 3.52E-OI O.OOE+OO 5.0IE-07 

9.00E+OO 3.08E-04 3.24E-OI O.OOE+OO 4.60E-07 

I.OOE+OI 3.08E-04 2. 97E-OI O.OOE+OO 4. 22E-07 

2.00E+OI 2.06E-04 I.27E-OI O.OOE+OO I.78E-07 

3.00E+OI I.OlE-04 5. 47E-02 O.OOE+OO 7. 53E-08 

4.00E+OI 4. 45E-05 2. 35E-02 O.OOE+OO 3.18E-08 

5.00E+OI I.87E-05 I.OIE-02 O.OOE+OO . 1. 34E-08 

6.00E+OI 7. 68E-06 4.3SE-03 O.OOE+OO 5. 67E-09 

7.00E+OI 3. llE-06 I.87E-03 O.OOE+OO 2.39E-09 

8.00E+OI 1. 25E-06 8.03E-04 O.OOE+OO I.OIE-09 

9.00E+OI 4. 99E-07 3. 44E-04 O.OOE+OO 4. 27E-1O 

I.OOE+02 1. 99E-07 I.47E-04 O.OOE+OO 1.80E-1O 

'"'. 

B-588 
INGESTION f 1= 1.00E+OO BALFLIFE= 9.58E-Q2 DAYS IODINE 132 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI 24-HOUR TOTAL 

DAYS ORGANS THYROID TRACT URINE BODY 

I.OOE-OI 3. 88E-OI 2. 25E-02 4.40E-02 4. 32E-OI 

2.00E-OI I.75E-OI 2. 49E-02 I.94E-03 1. 77E-OI 

3.00E-OI 7. 35E-02 I.73E-02 8. 53E-05 7. 36E-02 

4.00E-OI 3.IIE-02 I.04E-02 3.80E-06 3.IIE-02 

5.00E-OI 1. 34E-02 5.78E-03 1. 88E-07 1. 34E-02 

6.00E-OI 5.86E-03 3.06E-03 1.80E-08 5. 86E-03 

7.00E-OI 2.6lE-03 I.58E-03 O.OOE+OO 2.6lE-03 

S.OOE-Ol I.I8E-03 8.01E-04 O.OOE+OO I.I8E-03 

9.00E-Ol 5. 43E-04 4.02E-04 O.OOE+OO 5. 43E-04 

l.OOE+OO 2. 52E-04 2.00E-04 O.OOE+OO 4. 55E-04 2. 52E-04 

2.00E+OO 1.57E-07 I.53E-07 O.OOE+OO 2. 35E-08 I.57E-07 

INGESTION fl= 1.00E+OO BALFLIFE= 9.58E-Q2 DAYS IODINE· 132 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-Ol 5. 26E-02 2.00E-09 

2.00E-Ol 5. 79E-02 4. 94E-09 

3.00E-OI 4.05E-02 5. 62E-09 

4.00E-OI 2.43E-02 4. 74E-09 

5.00E-0l 1.35E-02 3. 43E-09 

6.00E-OI 7.I6E-03 2. 26E-09 

7.00E-OI 3.70E-03 I.40E-09 

8.00E-Ol I. 88E-03 8. 25E-1O 

9.00E-0l 9.43E-04 4. 72E-lO 

I.OOE+OO 4. 69E-04 4. 69E-04 O.OOE+OO 2.63E-1O 

2.00E+OO 2. 42E-OS 3.62E-07 O.OOE+OO 3.76E-13 

B-589 
INGESTION fl= 1.OOE+OO STABLE CESIUM 133 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 9.07E-Ol 9.07E-02 9. 98E-Ol 

2.00E-Ol 9.86E'-Ol 8.23E-03 9. 94E-Ol 

3.00E-Ol 9.89E-Ol 7. 48E-04 9.90E-Ol 

4.00E-Ol 9.86E-Ol 6. 86E-OS 9.86E-Ol 

S.OOE-Ol 9.83E-Ol 7.02E-06 9. 83E-Ol 

6.00E-Ol 9.79E-Ol 1.38E-06 9.79E-Ol 

7.00E-Ol 9.76E-Ol 8.30E-07 9.76E-Ol 

8.00E-Ol 9.73E-Ol 7.3SE-07 9. 73E-Ol 

9.00E-Ol 9.69E-Ol 6. 83E-07 9. 69E-Ol 

1.OOE+OO 9.66E-Ol 6.3SE-07 9.66E-Ol 

2.00E+OO 9.40E-Ol 2. 76E-07 9.40E-Ol 

3.00E+OO 9.l9E-Ol 1.08E-07 9.l9E-Ol 

4.00E+OO 9.03E-Ol 4.09E-08 9.03E-Ol 

S.OOE+OO 8.90E-Ol 1.S2E-08 8.90E-Ol 

6.00E+OO 8. 79E-Ol O.OOE+OO 8. 79E-Ol 

7.00E+OO 8.70E-Ol O.OOE+OO 8.70E-Ol 

8.00E+OO 8.62E-Ol O.OOE+OO 8. 62E-Ol 

9.00E+OO 8.SSE-Ol O.OOE+OO 8.SSE-Ol 

1.OOE+Ol 8.48E-Ol O.OOE+OO 8.48E-Ol 

2.00E+Ol 7.94E-Ol O.OOE+OO 7.94E-Ol 

3.00E+Ol 7.4SE-Ol O.OOE+OO 7.4SE-0l 

4.00E+Ol 7.00E-Ol O.OOE+OO 7.00E-Ol 

S.OOE+Ol 6.S7E-Ol O.OOE+OO 6.S7E-Ol 

6.00E+Ol 6.l7E-Ol O.OOE+OO 6.l7E-Ol 

7.00E+Ol S.79E-Ol O.OOE+OO S.79E-Ol 

8.00E+Ol S.44E-Ol O.OOE+OO S.44E-Ol 

9.00E+Ol S.llE-Ol O.OOE+OO S.llE-Ol 

1.OOE+02 4.79E-Ol O.OOE+OO 4. 79E-Ol 

2.00E+02 2.SSE-Ol O.OOE+OO 2.SSE-Ol 

3.00E+02 1.36E-Ol O.OOE+OO 1. 36E-Ol 

4.00E+02 7.24E-02 O.OOE+OO 7. 24E-02 

S.OOE+02 3.86E-02 O.OOE+OO 3. 86E-02 

6.00E+02 2.0SE-02 O.OOE+OO 2.0SE-02 

7.00E+02 1.09E-02 O.OOE+OO 1.09E-02 

8.00E+02 S.83E-03 O.OOE+OO S.83E-03 

9.00E+02 3.l0E-03 O.OOE+OO 3.l0E-03 

1.OOE+03 1.6SE-03 O.OOE+OO 1.6SE-03 

2.00E+03 3.04E-06 O.OOE+OO 3.04E-06 

B-S90 
INGESTION f 1- 1.00E+OO STABLE CESIUM 133 

TIME AFTER FRACTION Of INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1. 98E-03 4. 96E-04 

2.00E-Ol 5.00E-03 1.25E-03 

3.00E-Ol 8.02E-03 2.01E-03 

4.00E-Ol 1.10E-02 2.74E-03 

5.00E-Ol 1. 38E-02 3. 46E-03 

6.00E-Ol 1. 66E-02 4. 15E-03 

7.00E-Ol 1. 93E-02 4. 83E-03 

8.00E-Ol 2. 19E-02 5.48E-03 

9.00E-Ol 2. 45E-02 6. 12E-03 

1.00E+00 2.70E-02 2.70E-02 6. 74E-03 6. 74E-03 

2.00E+00 2. 13E-02 4. 83E-02 5.33E-03 1.21E-02 

3.00E+00 1. 64E-02 6. 46E-02 4.09E-03 1. 62E-02 

4.00E+00 1. 28E-02 7. 75E-02 3. 21E-03 1.94E-02 

5.00E+00 1.04E-02 8. 78E-02 2. 59E-03 2.20E-02 

6.00E+00 8. 58E-03 9. 64E-02 2. 15E-03 2.41E-02 

7.00E+00 7. 32E-03 1.04E-Ol 1. 83E-03 2. 59E-02 

8.00E+00 6. 43E-03 1.1OE-Ol 1.61E-03 2.75E-02 

9.00E+00 5. 78E-03 1. 16E-Ol 1. 45E-03 2.90E-02 

1.00E+Ol 5. 32E-03 1.21E-Ol 1.33E-03 3.03E-02 

2.00E+Ol 4.05E-03 1. 65E-Ol 1.01E-03 4. 12E-02 

3.00E+01 3. 77E-03 2.04E-Ol 9. 42E-04 5.10E-02 

4.00E+01 3. 54E-03 2.40E-01 8. 84E-04 6.01E-02 

5.00E+01 3. 32E-03 2. 74E-Ol 8.30E-04 6. 86E-02 

6.00E+01 3. 12E-03 3.07E-Ol 7.80E-04 7.66E-02 

7.00E+01 2. 93E-03 3. 37E-01 7.32E-04 8. 42E-02 

8.00E+01 2. 75E-03 3. 65E-Ol 6. 87E-04 9.12E-02 

9.00E+Ol 2. 58E-03 3.91E-01 6. 45E-04 9. 79E-02 

1.00E+02 2. 42E-03 4. 16E-01 6.06E-04 1.04E-Ol 

2.00E+02 1.29E-03 5. 96E-Ol 3. 23E-04 1. 49E-Ol 

3.00E+02 6. 88E-04 6.91E-Ol 1. 72E-04 1. 73E-Ol 

4.00E+02 3.66E-04 7. 42E-Ol 9. 16E-05 1.86E-Ol 

5.00E+02 1. 95E-04 7. 69E-Ol 4. 88E-05 1. 92E-Ol 

6.00E+02 1.04E-04 7.84E-Ol 2.60E-05 1.96E-Ol 

7.00E+02 5. 53E-05 7.91E-Ol 1.38E-05 1.98E-Ol 

8.00E+02 2. 95E-05 7. 95E-Ol 7. 37E-06 1.99E-Ol 

9.00E+02 1. 57E-05 7.98E-Ol 3. 92E-06 1. 99.E-Ol 

1.00E+03 8. 36E-06 7.99E-Ol 2.09E-06 2.00E-Ol 

2.00E+03 1. 53E-08 8.00E-Ol O.OOE+OO 2.00E-Ol 

B-591 
INGESTION f 1= 1.00E+OO BALFLIFE- 1.10E+04 DAYS CESIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------~--------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 9.07E-Ol 9.07E-02 9. 98E-Ol 

2.00E-Ol 9.86E-Ol 8. 23E-03 9.94E-01 

3.00E-Ol 9.89E-Ol 7. 48E-04 9.90E-01 

4.00E-Ol 9.86E-Ol 6.86E-05 9.86E-01 

5.00E-01 9.83E-Ol 7.02E-06 9. 83E-Ol 

6.00E-Ol 9.79E-Ol 1. 38E-06 9.79E-Ol 

7.00E-Ol 9. 76E-Ol 8. 29E-07 9.76E-Ol 

8.00E-Ol 9. 73E-Ol 7.35E-07 9. 73E-Ol 

9.00E-Ol 9.69E-Ol 6.83E-07 9. 69E-01 

1.00E+00 9.66E-Ol 6.35E-07 9.66E-Ol 

2.00E+00 9.40E-Ol 2. 76E-07 9.40E-Ol 

3.00E+00 9. 19E-Ol 1.08E-07 9. 19E-Ol 

4.00E+00 9.03E-Ol 4.09E-08 9.03E-Ol 

5.00E+00 8.90E-Ol 1.52E-08 8.90E-Ol 

6.00E+00 8. 79E-Ol O.OOE+OO 8. 79E-Ol 

7.00E+00 8.70E-Ol O.OOE+OO 8.70E-Ol 

8.00E+00 8.62E-Ol O.OOE+OO 8. 62E-Ol 

9.00E+00 8. 55E-Ol O.OOE+OO 8.55E-Ol 

1.00E+Ol 8. 48E-Ol O.OOE+OO 8. 48E-Ol 

2.00E+Ol 7.93E-Ol O.OOE+OO 7. 93E-Ol 

3.00E+Ol 7.44E-Ol O.OOE+OO 7. 44E-Ol 

4.00E+Ol 6. 98E-Ol O.OOE+OO 6. 98E-Ol 

5.00E+Ol 6.55E-Ol O.OOE+OO 6. 55E-Ol 

6.00E+Ol 6.15E-Ol O.OOE+OO 6. 15E-Ol 

7.00E+Ol 5.77E-Ol O.OOE+OO 5.77E-Ol 

8.00E+Ol 5.41E-Ol O.OOE+OO 5.41E-Ol 

9.00E+Ol 5.08E-Ol O.OOE+OO 5.08E-Ol 

1.00E+02 4. 76E-Ol O.OOE+OO 4. 76E-Ol 

2.00E+02 2. 52E-0l. O.OOE+OO 2. 52E-Ol 

3.00£+02 1.33E-Ol O.OOE+OO 1. 33E-Ol 

4.00E+02 7.06E-02 O.OOE+OO 7.06E-02 

5.00E+02 3. 74E-02 O.OOE+OO 3. 74E-02 

6.00E+02 1.98E-02 O.OOE+OO 1.98E-02 

7.00E+02 1.05E-02 O.OOE+OO 1.05E-02 

8.00E+02 5. 54E-03 O.OOE+OO 5. 54E-03 

9.00E+02 2.93E-03 O.OOE+OO 2. 93E-03 

1.00E+03 1. 55E-03 O.OOE+OO 1.55E-03 

2.00E+03 2.67E-06 O.OOE+OO 2. 67E-06 

B-592 
INGESTION fl= 1.00E+OO HALFLIFE= 1.10£+04 DAYS CESIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE l 

------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 1. 98E-03 4 .. 96E-04 

2.00E-OI 5.00E-03 1. 25E-03 

3.00E-OI 8.02E-03 2.0IE-03 

4.00E-OI 1. IOE-02 2. 74E-03 

5.00E-OI 1. 38E-02 3.46E-03 

6.00E-OI 1. 66E-02 4.15E-03 

7.00E-OI I.93E-02 4. 83E-03 

8.00E-OI 2.19E-02 5.48E-03 

9.00E-OI 2. 45E-02 6.I2E-03 

I.OOE+OO 2.70E-02 2.70E-02 6. 74E-03 6. 74E-03 

2.00E+OO 2.13E-02 4. 83E-02 5.33E-03 I.2IE-02 

3.00E+OO 1. 64E-02 6.46E-02 4 .. 09E-03 1. 62E-02 

4.00E+OO I.28E-02 7.75E-02 3.2IE-03 1. 94E-02 

5.00E+OO I.03E-02 8. 78E-02 2. 59E-03 2.20E-02 

6.00E+OO 8.S8E-03 9. 64E-02 2.14E-03 2.4IE-02 

7.00E+OO 7. 32E-03 I.04E-OI 1. 83E-03 2. 59E-02 

8.00E+OO 6. 42E-03 I.IOE-Ol I.6IE-03 2.7SE-02 

9.00E+OO S.78E-03 I.I6E-OI 1. 44E-03 2.90E-02 

I.OOE+OI S.32E-03 I.2IE-OI I.33E-03 3.03E-02 

2.00E+OI 4 .. 04E-03 I.6SE-OI I.OIE-03 4.12E-02 

3.00E+OI 3.76E-03. 2.03E-OI 9.40E-04 5.09E-02 

4.00E+OI 3. 53E-03 2.40E-OI 8. 82E-04 S.99E-02 

S.OOE+OI 3.3IE-03 2. 74E-OI 8. 28E-04 6. 84E-02 

6.00E+OI 3.IIE-03 3.05E-OI 7.77E-04 7. 63E-02 

7.00E+OI 2. 92E-03 3. 35E-OI 7. 29E-04 8. 38E-02 

8.00E+OI 2. 74E-03 3. 63E-OI 6. 84E-04 9.08E-02 

9.00E+OI 2.S7E-03 3. 89E-OI 6.42E-04 9. 73E-02 

I.OOE+02 2.4IE-03 4.14E-OI 6 .. 02E-04 I.03E-OI 

2.00E+02 I.27E-03 5.88E-0l 3.19E-04 I.47E-OI 

3.00E+02 6. 75E-04 6. 78E-OI 1 .. 69E-04 I.70E-OI 

4.00E+02 3. 57E-04 7. 23E-OI 8. 93E-05 I.8IE-OI 

S.OOE+02 1.89E-04 7.4SE-OI 4.72E-OS 1. 86E-OI 

6.00E+02 I.OOE-04 7. S4E-OI 2.50E-05 I.89E-OI 

7 .. 00E+02 S.29E-05 7.S7E-OI 1. 32E-OS I.89E-OI 

8.00E+02 2.80E-OS 7. 56E-OI 7.00E-06 I.89E-OI 

9.00E+02 1. 48E-OS 7. 53E-OI 3.71E-06 1. 88E-OI 

I.OOE+03 7.8SE-06 7.50E-OI I.96E-06 I.87E-OI .. 

.. 2.00E+03 I.3SE-08 7.05E-OI O.OOE+OO 1. 76E-OI 

B-S93 
INGESTION £1= 1.00E-ol STABLE BARIUM 137 

TIHE AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------~----------------------------------------------

SYSTEHIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 1.80E-02 9.67E-Ol 9.85E-Ol 

2.00E-Ol 2.95E-02 9.30E-Ol 9.60E-Ol 

3.00E-Ol 3.46E-02 9.00E-Ol 9.35E-Ol 

4.00E-Ol 3. 64E-02 8.70E-Ol 9.06E-Ol 

5.00E-Ol 3.66E-02 8.37E-Ol 8.74E-Ol 

6.00E-Ol 3.59E-02 8.01E-Ol 8.37E-Ol 

7.00E-01 3.50E-02 7.62E-Ol 7.96E-Ol 

8.00E-Ol 3.38E-02 7.20E-Ol 7.54E-Ol 

9.00E-Ol 3. 26E-02 6. 78E-Ol 7.11E-Ol 

1.00E+00 3. 14E-02 6. 36E-Ol 6.67E-Ol 

2.00E+00 2.21E-02 2.87E-Ol 3.09E-Ol 

3.00E+00 1.65E-02 1. 14E-01 1.30E-01 

4.00E+00 1. 31E-02 4.32E-02 5.63E-02 

5.00E+00 1.10E-02 1.61E-02 2.71E-02 

6.00E+00 9. 56E-03 5. 95E-03 1. 55E-02 

7.00E+00 8.60E-03 2. 19E-03 1.08E-02 

8.00E+00 7.92E-03 8.08E-04 8. 73E-03 

9.00E+00 7.43E-03 2. 97E-04 7. 73E-03 

1.00E+01 7.06E-03 1.09E-04 7.17E-03 

2.00E+01 5.81E-03 O.OOE+OO 5.81E-03 

3.00E+01 5. 56E-03 O.OOE+OO 5. 56E-03 

4.00E+01 5.40E-03 O.QOE+OO 5.40E-03 

5.00E+Ol 5. 25E-03 O.OOE+OO 5. 25E-03 

6.00E+01 5. 12E-03 O.OOE+OO 5. 12E-03 

7.00E+Ol 5.00E-03 O.OOE+OO 5.00E-03 

8.00E+Ol 4.88E-03 O.OOE+OO 4. 88E-03 

9.00E+Ol 4.77E-03 O.OOE+OO 4.77E-03' 

1.00E+02 4. 67E-03 O.OOE+OO 4. 67E-03 

2.00E+02 3. 92E-03 O.OOE+OO 3.92E-03 

3.00E+02 3.49E-03 O.OOE+OO 3. 49E-03 

4.00E+02 3.20E-03 O.OOE+OO 3.20E-03 

5.00E+02 3.00E-03 O.OOE+OO 3.00E-03 

6.00E+02 2.84E-03 O.OOE+OO 2. 84E-03 

7.00E+02 2.70E-03 O.OOE+OO 2.70E-03 

8.00E+02 2. 59E-03 O.OOE+OO 2. 59E-03 

9.00E+02 2. 48E-03 O.OOE+OO 2. 48E-03 

1.00E+03 2. 39E-03 O.OOE+OO 2.39E-03 

2.00E+03 1. 75E-03 O.OOE+OO 1. 75E-03 

3.00E+03 1.39E-03 O.OOE+OO 1. 39E-03 

4.00E+03 1.13E-03 O.OOE+OO 1. 13E-03 

5.00E+03 9.48E-04 O.OOE+OO 9.48E-04 

7.00E+03 6. 88E-04 O.OOE+OO 6. 88E-04 

8.00E+03 5. 94E-04 O.OOE+OO 5. 94E-04 

9.00E+03 5. 15E-04 O.OOE+OO 5. 15E-04 

1.00E+04 4. 49E-04 O.OOE+OO 4. 49E-04 

2.00E+04 1.21E-04 O.OOE+OO 1.21E-04 

B-594 
INGESTION fl= 1.00E-ol STABLE BARIUM 137 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1. 44E-03 1. 36E-02 

2.00E-Ol 3. 43E-03 3. 66E-02 

3.00E-Ol 4.67E-03 6.07E-02 

4.00E-Ol 5.40E-03 B.B3E-02 

5.00E-O} 5.B5E-03 1.21E-Ol 

6.00E-Ol 6.15E-03 1.57E-Ol 

7.00E-Ol 6. 37E-03 1.97E-Ol 

B.OOE-Ol 6. 55E-03 2. 39E-Ol 

9.00E-Ol 6.71E-03 2.B3E-Ol 

1.00E+OO 6.B4E-03 6.B4E-03 3. 26E-Ol 3. 26E-Ol 

2.00E+OO 9.51E-04 7. 79E-03 3.57E-Ol 6.B4E-Ol 

3.00E+OO 5. 57E-04 B.3SE-03 1.7BE-Ol B.61E-Ol 

4.00E+OO 3.40E-04 B.69E-03 7.36E-02 9. 35E-Ol 

S.OOE+OO 2. 15E-04 B.90E-03 2.90E-02 9. 64E-Ol 

6.00E+OO 1.41E-04 9.04E-03 1.14E-02 9. 75E-Ol 

7.00E+OO 9.61E-05 9.14E-03 4. 62E-03 9. BOE-Ol 

B.OOE+OO 6.7BE-05 9.21E-03 2.00E-03 9.B2E-Ol 

9.00E+OO 4. 94E-05 9. 26E-03 9. 55E-04 9.B3E-Ol 

1.OOE+Ol 3. 69E-05 9. 29E-03 5.20E-04 9.B4E-Ol 

2.00E+Ol 4.4BE-06 9. 42E-03 4.03E-05 9.B5E-Ol 

3.00E+Ol 1.B4E-06 9. 44E-03 1.66E-05 9.B5E-Ol 

4.00E+Ol 1.SOE-06 9.46E-03 1. 35E-05 9.B5E-Ol 

5.00E+Ol 1.3BE-06 9. 47E-03 1.25E-05 9.B5E-Ol 

6.00E+Ol 1.29E-06 9. 49E-03 1. 16E-05 9.B5E-Ol 

7.00E+0l 1.21E-06 . 9.50E-03 1.09E-05 9.B6E-Ol 

B.OOE+Ol 1.13E-06 9.51E-03 1.02E-OS 9.B6E-Ol 

9.00E+Ol 1.06E-06 9. S2E-03 9.57E-06 9;B6E-Ol 

1.00E+02 9.9BE-07 9. 53E-03 B.9BE-06 9.B6E-Ol 

2.00E+02 5. 54E-07 9. 61E-03 4. 99E-06 9.B6E-Ol 

3.00E+02 3. 42E-07 9. 65E-03 3.07E-06 9.B7E-Ol 

4.00E+02 2. 35E-07 9.6BE-03 2. 12E-06 9.B7E-Ol 

5.00E+02 1. 79E-07 9.70E-03 1.61E-06 9.B7E-Ol 

6.00E+02 1.46E-07 9.72E-03 1. 32E-06 9.B7E-Ol 

7.00E+02 1.2SE-07 9. 73E-03 1.13E-06 9.BBE-Ol 

B.OOE+02 1.1OE-07 9. 74E-03 9. 94E-07 9.BBE-Ol 

9.00E+02 9.9lE-OB 9. 75E-03 B.92E-07 9.BBE-Ol ~ " 1.00E+03 9.00E-OB 9. 76E-03 B.lOE-07 9.BBE-Ol 

2.00E+03 4. 57E-OB 9.B2E-03 4.llE-07 9. BBE-O 1 

3.00E+03 2.9BE-OB 9.B6E-03 2.6BE-07 9.B9E-Ol 

4.00E+03 2.lSE-OB 9.B9E-03 1. 93E-07 9.B9E-Ol 

5.00E+03 1.63E-OB 9.9lE-03 1.47E-07 9. 89E-Ol 

6.00E+03 1.2BE-OB 9. 92E-03 1. 15E-07 9.B9E-Ol 

7.00E+03 1.04E-OB 9. 93E-03 9.32E-OB 9.B9E-Ol 

B-S95 
INGESTION £1= I.OOE-ol IlALPLIFE= I.27E+OI DAYS BAllIUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 1.79E-02 9.62E-Ol 9.80E-Ol 

2.00E-OI 2. 92E-02 9.20E-Ol 9.50E-Ol 

3.00E-Ol 3.40E-02 8.8SE-Ol 9.19E-Ol 

4.00E-Ol 3. 56E-02 8.S1E-OI 8. 87E-Ol 

S.OOE-Ol 3.S6E-02 8.14E-Ol 8.S0E-Ol 

6.00E-OI 3. 48E':"02 7.7SE-Ol 8.lOE-01 

7.00E-OI 3. 36E-02 7.33E-OI 7.67E-Ol 

8.00E-Ol 3. 24E-02 6.90E-Ol 7.22E-Ol 

9.00E-Ol 3.lOE-02 6. 46E-Ol 6. 77E-Ol 

1.00E+00 2. 98E-02 6.02E-Ol 6.32E-Ol 

2.00E+OO 1.98E-02 2.S7E-Ol 2. 77E-Ol 

3.00E+OO 1.40E-02 .9.66E-02 1. llE-Ol 

4.00E+OO 1.06E-02 3. 47E-02 4. 53E-02 

S.OOE+OO 8. 36E-03 1~23E-02 2.06E-02 

6.00E+OO 6.90E-03 4. 29E-03 1.12E-02 

7.00E+OO S.88E-03 I.SOE-03 7. 38E-03 

8.00E+OO S.13E-03 S.23E-04 5.6SE-03 

9.0QE+00 4.SSE-03 1.8ZE-04 4. 74E-03 

1.00E+OI 4. lOE-03 6. 35E-05 4.16E-03 

2.00E+Ol 1. 96E-03 O.OOE+OO 1. 96E-03 

3.00E+Ol I.09E-03 O.OOE+OO 1.09 

4.00E+Ol 6.IZE-04 O.OOE+OO 6.l2E-04 

5.00E+Ol 3.46E-()4 O.OOE+OO 3. 46E-04 

6.00E+Ol 1.96E-04 O.OOE+OO 1. 96E-04 

7.00E+OI 1.IIE-04 O.OOE+OO 1. llE-04 

8.00E+Ol ·6.Z8E-05 O.OOE+OO 6. 28E-05 

9.00E+Ol 3.S6E-05 O.OOE+OO 3.S6E-05 

1.00E+02 2.02E-05 O.OOE+OO 2.02E-05 

2.00E+02 7.37E-08 O.OOE+OO 7. 37E-08 

B-596 
~. '. ,. , ~- ~ 

,',." ... -'-, 

INGESTION 

TIME AFTER 

SINGLE INTAKE 

DAYS 

1.00E-Ol 

2.00E-Ol 

3.00E-Ol 

4.00E-Ol 

5.00E-Ol 

6.00E-Ol 

7.00E-Ol 

8.00E-Ol 

9.00E-Ol 

1.00E+00 

2.00E+00 

3.00E+00 

4.00E+00 

5.00E+00 

6.00E+00 

7.00E+00 

8.00E+00 

9.00E+00 

1.00E+Ol 

2.00E+Ol 

3.00E+Ol 

4.00E+Ol 

5.00E+Ol 

6.00E+Ol 

7.00E+Ol 

8.00E+Ol 

f 1- 1.00E-ol BALFLlFE= 1.27E+Ol DAYS MRIUH 140 

FRACTION OF INITIAL INTAKE IN: 

------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

URINE URINE FECES FECES 

1.43E-03 1. 35E-02 

3.40E-03 3. 62E-02 

4.60E-03 5. 97E-02 

5. 28E-03 8. 64E-02 

5. 69E-03 1. 17E-Ol 

5. 95E-03 1. 52E-Ol 

6. 14E-03 1.90E-01 

6. 27E-03 2. 29E-Ol 

6. 38E-03 2. 69E-Ol 

6. 48E-03 6. 48E-03 3.09E-Ol 3.09E-Ol 

8. 53E-04 6. 99E-03 3. 21E-Ol 6. 13E-Ol 

4. 73E-04 7.09E-03 1. 51E-Ol 7. 32E-Ol 

2. 73E-04 6. 99E-03 5. 92E-02 7.52E-Ol 

1. 64E-04 6. 78E-03 2. 21E-02 7.34E-Ol 

1.02E-04 6. 52E-03 8. 23E-03 7.04E-Ol 

6. 56E-05 6. 25E-03 3. 16E-03 6.70E-Ol 

4. 39E-05 5. 96E-03 1. 29E-03 6. 35E-Ol 

3.03E-05 5. 67E-03 5. 85E-04 6.02E-Ol 

2. 14E-05 5. 39E-03 3.02E-04 5.71E-Ol 

1. 51E-06 3. 17E-03 1. 36E-05 . 3. 32E-Ol 

3.60E-07 1. 85E-03 3. 24E-06 1.93E-Ol 

1.70E-07 1.07E-03 1. 53E-06 1. 12E-Ol 

9. 12E-08 6. 24E-04 8.20E-07 6. 49E-02 

4. 94E-08 3. 63E-04 4. 45E-07 3. 77E-02 

2. 69E-08 2. l1E-04 2. 42E-07 2. 19E-02 

1. 46E-08 1. 22E-04 1.31E-07 1. 27E-02 

B-597 
INGESTION f 1'''' 1.00E-03 STABLE J..ARTIJANUM 139 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 2. 99E-04 9. 99E-01 9. 99E-01 

2.00E-01 6.01E-04 9.9~~-01 9. 94E-01 

3.00E-01 7.80E-04 9.8'OE-01 9.81E-01 

4. OOE-O 1 8. 79E-04 9.58E-Ol 9.58E-01 

5.00E-Ol 9.34E-04 9.27E-01 9.28E-Ol 

6.00E-01 9. 64E-04 8.91E-01 8. 92E-01 

7.00E-01 9.80E-04 8.50E-01 8.51E-01 

8.00E-01 9. 89E-04 8.05E-01 8.06E-01 

9.00E-01 9. 94E-04 7. 59E-01 7.60E-01 

1.00E+00 9. 97E-04 7.13E-01 7. 14E-01 

2.00E+00 1.00E-03 3. 23E-01 3. 24E-01 

3.00E+00 9. 99E-04 1. 29E-01 1.30E-01 

4.00£+00 9. 99E-04 4. 88E-02 4. 98E-02 

5.00E+00 9.99£-04 1. 82E-02 1.92E-02 

6.00E+00 9.99E-04 6. 74E-03 7.73£-03 

7.00£+00 9. 99E-04 2. 48E-03 3. 48E-03 

8.00E+00 9. 98E-04 9.15E-04 1.91E-03 

9.00E+00 9.98E-04 3. 37E-04 1. 33E-03 

1~00E+01 9.98E-04 1~24E-04 1. 12E-OJ 

2.00E+01 9. 96E-04 O.OOE+OO 9. 96E-04 

3.00E+01 9. 94E-04 O.OOE+OO 9. 

4.00E+01 9. 92E-04 O.OOE+OO 9. 

5.00E+01 9.90E-04 O.OOE+OO 9.90E-04 

6.00E+Ol 9.88£-04 O.OOE+OO 9. 88E-04 

7.00E+01 9.86E-04 O.OOE+OO 9.86E-04 

8.00E+Ol 9. 84E-04 O.OOE+OO 9~ 84E-04 

9.00E+Ol 9.82E-04 O.OOE+OO 9. 82E-04 

1.00E+02 9.80E-04 O.OOE+OO 9.80E-04 

2.00E+02 9. 61E-04 O.OOE+OO 9. 61E-04 

3.00E+02 9.42E-04 O.OOE+OO 9. 42E-04 

4.00E+02 9. 24E-04 O.OOE+OO 9. 24E-04 

5.00E+02 9.06E-04 O.OOE+OO 9.06E-04 

6.00E+02 8. 88E-04 O.OOE+OO 8. 88E-04 

7.00E+02 8.71E-04 O.OOE+OO 8.71E-04 

8.00E+02 8.54E-04 O.OOE+OO 8. 54E-04 

9.00E+02 8.37E-04 O.OOE+OO 8. 37E-04 "0 J. 1.00E+03 8.20E-04 O.OOE+OO 8.20E-04 

2.00E+03 6. 73E-04 O.OOE+OO 6. 73E-04 

3.00E+03 5. 52E-04 O.OOE+OO 5. 52E-04 

4.00E+03 4. 53E-04 O.OOE+OO 4. 53E-04 

5.00E+03 3.72E-04 O.OOE+OO 3.72E-04 

7.00E+03 2.50E-04 O.OOE+OO 2.50E-04 

8.00E+03 2.05E-04 O.OOE+OO 2.05E-04 

9.00E+03 1. 68E-04 O.OOE+OO 1.68E-04 

1.00E+04 1. 38E-04 O.OOE+OO 1. 38E-04 

2.00E+04 1.91E-05 0.00£+00 1.91E-05 

B-598 
INGESTION £1= 1.00E-03 STABLE LANTHANUM 139 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- --~-----~--------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol O.OOE+OO 6.l0E-04 

2.00E-Ol O.OOE+OO S.90E-03 

3.00E-Ol O.OOE+OO l.94E-02 

4.00E-Ol O.OOE+OO 4. 16E-02 

S.OOE-01 O.OOE+OO 7. 18E-02 

6.00E-OI O.OOE+OO 1.08E-01 

7.00E-01 O.OOE+OO 1.49E-01 

8.00E-01 O.OOE+OO I.94E-OI 

9.00E-OI O.OOE+OO 2.40E-OI 

1.00E+OO O.OOE+OO O.OOE+OO 2.86E-01 2. 86E-OI 

2.00E+OO O.OOE+OO O.OOE+OO 3.90E-OI 6.76E-OI 

3.00E+OO O.OOE+OO O.OOE+OO I.9SE-01 8.71E-01 

4.00E+OO O.OOE+OO O.OOE+OO 7.98E-02 9.S1E-01 

S.OOE+OO O.OOE+OO O.OOE+OO 3.07E-02 9.B1E-01 

6.00E+OO O.OOE+OO O.OOE+OO 1.lSE-02 9.93E-01 

7.00E+OO O.OOE+OO O.OOE+OO 4. 26E-03 9.97E-01 

8.00E+OO O.OOE+OO O.OOE+OO 1.S7E-03 9. 99E-OI 

9.00E+OO O.OOE+OO O.OOE+OO S.79E-04 9. 99E-Ol 

1.00E+01 O.OOE+OO O.OOE+OO 2.13E-04 1.00E+OO 

2.00E+01 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

3.00E+01 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

4.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

S.OOE+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

6.00E+01 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

7.00E+01 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

8.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

9.00E+01 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO . 1.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

2.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

3.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

4.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

S.OOE+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

6.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

7.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO , . 8.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

9.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

I.OOE+03 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

2.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

3.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

4.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

S.OOE+03 O.OOE+OO O.OOE+OO O.OOE+OO I.OOE+OO 

6.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

7.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

8.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.00E+OO 

B-599 
INGESTION fl= 1.00E-03 IlALFLlFE= 1.68E+OO DAYS LANTHANIJH 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2. 87E-04 9.S9E-OI 9.S9E-OI 

2.00E-OI S.54E-04 9.ISE-OI 9.ISE-OI 

3.00E-OI 6. 89E-04 8.66E-OI 8. 66E-OI 

4.00E-OI 7.45E-04 8.12E-OI 8.12E-OI 

S.OOE-OI 7.S9E-04 7.54E-OI 7.55E-OI 

6.00E-OI 7.S2E-04 6.95E-OI 6. 96E-OI 

7.00E-OI 7. 34E-04 6. 36E-OI 6. 37E-OI 

8.00E-OI 7.IIE-04 5.79E-OI S.79E-Ol 

9.00E-Ol 6.85E-04 5.24E-OI 5.24E-OI 

I.OOE+OO 6. 59E-04 4.72E-OI 4.72E-OI 

2.00E+OO 4. 38E-04 I.42E-OI I.42E-OI 

3.00E+OO 2.89E-04 3.72E-02 3.7SE-02 

4.00E+OO l.9IE-04 9.36E-03 9.55E-03 

5.00E+OO l.27E-04 2.3IE-03 2.43E-03 

6.00E+OO 8. 38E-05 5. 65E-04 6. 49E-04 

7.00E+OO 5. 54E-OS I.38E-04 1. 93E-04 

B.OOE+OO 3. 67E-05 3. 36E-05 7.02E-05 . I 9.00E+OO 2.42E-05 B.IBE-06 3. 24E-OS 

1.00E+Ol 1.60E-05 1. 99E-06 1.80E-OS 

2.00E+Ol 2.S7E-07 O.OOE+OO 2.S7E-07 

B-600 
INGESTION £1= 1.00E-03 BALFLIFE= 1.68E+OO DAYS LANTIIANOM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-01 O.OOE+OO 5.71E-04 

2.00E-Ol O.OOE+OO 5.31E-03 

3.00E-Ol O.OOE+OO 1. 67E-02 

4.00E-Ol O.OOE+OO 3. 45E-02 

5.00E-Ol O.OOE+OO 5. 72E-02 

6.00E-Ol O.OOE+OO 8. 29E-02 

7.00E-Ol O.OOE+OO 1.lOE-Ol 

8.00E-Ol O.OOE+OO 1.37E-Ol 

9.00E-Ol O.OOE+OO 1.63E-Ol 

1.OOE+OO O.OOE+OO O.OOE+OO 1.87E-01 1. 87E-Ol 

2.00E+OO O.OOE+OO O.OOE+OO 1.70E-01 2. 94E-Ol 

3.00E+00 O.OOE+OO O.OOE+OO 5.70E-Ol 2.51E-Ol 

4.00E+OO O.OOE+OO O.OOE+OO 1.56E-02 1.82E-Ol 

5.00E+OO O.OOE+OO O.OOE+OO 3. 98E-03 1. 24E-Ol 

6.00E+OO O.OOE+OO O.OOE+OO 9.89E-04 8. 32E-02 

7.00E+OO O.OOE+OO .O.OOE+OO 2. 43E-04 5. 53E-02 

8.00E+OO O.OOE+OO O.OOE+OO 5. 93E-05 3. 66E-02 

8-601 
INGESTION £1= 3.00E-04 STABLE CERIUM 140 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------~ 

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol B.96E-05 9.99E-Ol 9. 99E-Ol 

2.00E-Ol 1. BOE-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 2.34E-04 9. BOE-Ol 9.81E-0l 

4.00E-Ol 2. 64E-04 9.5SE-Ol 9. 58E-Ol 

5.00E-Ol 2. BOE-04 9. 28E-Ol 9.2BE-Ol 

6.00E-Ol 2. 89E-04 8.91E-0l 8. 92E-Ol 

7.00E-Ol 2. 94E-04 8.50E-Ol 8.51E-Ol 

8.00E-Ol 2.97E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 2. 98E-04 7.60E-Ol 7.60E-0l 

1.OOE+OO 2. 99E-04 7.13E-Ol 7.14E-Ol 

2.00E+OO 3.00E-04 3.24E-Ol 3.24E-Ol 

3.00E+OO 3.00E-04 1.29E-Ol I.29E-Ol 

4.00E+OO 3.00E-04 4. 89E-02 4. 92E-02 

5.00E+OO 3.00E-04 1. 82E-02 I.85E-02 

6.00E+OO 3.00E-04 6. 74E-03 7.04E-03 

7.00E+OO 3.00E-04 2. 49E-03 2. 79E-O'l 

8.00E+OO 3.00E-04 9.15E-04 1.2lE-03 

9.00E+OO 2. 99E-04 3. 37E-04 6. 36E-04 

1.OOE+Ol 2. 99E-04 1.24E-04 4. 23E-04 

2.00E+Ol 2. 99E-04 O.OOE+OO 2. 99E-04 

3.00E+Ol 2. 98E-04 O.OOE+OO 2.98E-04 

4.00E+OI 2. 98E-04 O.OOE+OO 2. 98E-04 

5.00E+Ol 2. 97E-04 O.OOE+OO 2.97E-04 

6.00E+Ol 2. 96E-04 O.OOE+OO 2.96E-04 

7.00E+Ol 2.96E-04 O.OOE+OO 2.96E-04 

8.00E+Ol 2.9SE-04 O.OOE+OO 2.9SE-04 

9.00E+Ol 2.95E-04 O.OOE+OO 2.9SE-04 

I.OOE+02 2.94E·"(,!-; O.OOE+OO 2. 94E-Q4 

2.00E+02 2. 88E-04 O.OOE+OO 2.88E-04 

3.00E+02 2. 83E-04 O.OOE+OO 2. 83E-04 

4.00E+02 2.77E-04 O.OOE+OO 2.77E-04 

S.OOE+02 2. 72E-04 O.OOE+OO 2. 72E-04 

6.00E+02 2. 66E-04 O.OOE+OO 2.66E-04 

7.00E+02 2.61E-04 O.OOE+OO 2.61E-04 

8.00E+02 2.S6E-04 O.OOE+OO 2. 56E-04 

9.00E+02 2.5lE-04 O.OOE+OO 2.S1E-04 

1.OOE+03 2.46E-04 O.OOE+OO 2.46E-04 

2.00E+03 2.02E-04 O.OOE+OO 2.02E-04 

3.00E+03 1. 66E-04 O.OOE+OO 1. 66E-04 

4.00E+03 1.36E-04 O.OOE+OO 1. 36E-04 

S.OOE+03 1. llE-04 O.OOE+OO 1.llE-04 

7.00E+03 7.S0E-05 O.OOE+OO 7.S0E-05 

8.00E+03 6.I5E-OS O.OOE+OO 6.15E-OS 

9.00E+03 5.0SE-05 O.OOE+OO 5.0SE-OS 

I.OOE+04 4.14E-05 O.OOE+OO 4.14E-OS 

2.00E+04 5. 72E-06 O.OOE+OO S.72E-06 

B-602 
INGESTION fl= 3.00K-G4 STABLE. CERIUM 140 

TIME AFTER FRACTION OF INItIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol O.OOE+OO 6.lOE-04 

2.00E-Ol O.OOE+OO 5.90E-03 

3.00E-Ol O.OOE+OO 1. 94E-02 

4.00E-Ol O.OOE+OO 4.l6E-02 

5.00E-Ol O.OOE+OO 7.l8E-02 

6.00E-Ol O.OOE+OO 1.08E-Ol 

7.00E-Ol O.OOE+OO 1. 49E-Ol 

8.00E-Ol O.OOE+OO 1. 94E-Ol 

9.00E-Ol O.OOE+OO 2.40E-Ol 

1.OOE+OO O.OOE+OO O.OOE+OO 2. 86E-Ol 2. 86E-Ol 

2.00E+OO O.OOE+OO O.OOE+OO 3.90E-Ol 6. 76E-Ol 

3.00E+OO O.OOE+OO O.OOE+OO 1.95E-Ol 8.71E-0l 

4.00E+OO O.OOE+OO O.OOE+OO 7. 98E-02 9.5lE-Ol 

5.00E+OO O.OOE+OO O.OOE+OO 3.07E-02 9.8lE-Ol 

6.00E+OO O.OOE+OO O.OOE+OO 1.15E-02 9. 93E-Ol 

7.00E+OO O.OOE+OO O.OOE+OO 4. 26E-03 9.97E-Ol 

8.00E+OO O.OOE+OO O.OOE+OO 1. 57E-03 9. 99E-Ol 

9.00E+OO O.OOE+OO O.OOE+OO 5. 79E-04 9.99E-Ol 

1.OOE+Ol O.OOE+OO O.OOE+OO 2.l3E-04 1.OOE+OO 

2.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

3.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

4.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

5.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

6.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

7.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

8.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

9.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

1.OOE+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

2.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

3.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

4.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO· 

5.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

6.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

7.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

8.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO ,. 9.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

1.OOE+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

2.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

3.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

4.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

5.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

6.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

7.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO 1.OOE+OO 

8.00E+03 O.OOE+OO O.OOE+OO O.OOE+OO l.OOE+OO 

B-603 
IRGESTION f 1- 3.001-04 BALFLIn- 3.25£+01 DAYS CER.IUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol B.94E-OS 9. 97E-Ol 9.97E-Ol 

2.00E-Ol 1. BOE-04 9.90E-Ol 9.90E-Ol 

3.00E-Ol 2. 32E-04 9. 74E-Ol 9.74E-OI 

4.00E-OI 2.6IE-04 9.S0E-Ol 9.S0E-Ol 

S.OOE-OI 2. 77E-04 9.IBE-OI 9.IBE-OI 

6.00E-OI 2. BSE-04 B.80E-OI 8.80E-0l 

7.00E-Ol 2.90E-04 8.38E-OI 8. 38E-OI 

8.00E-OI 2. 92E-04 7. 92E-OI 7. 93E-OI 

9.00E-OI 2. 92E-04 7.46E-OI 7. 46E-OI 

I.OOE+OO 2. 93E-04 6. 98E-OI 6. 98E-OI 

2.00E+OO 2. 87E-04 3.IOE-0l 3.IOE-0l 

3.00E+OO 2.8IE-04 1.2IE-OI 1.2IE-OI 

4.00E+OO 2.7SE-04 4. 49E-02 4.S2E-02 

S.OOE+OO 2. 69E-04 I. 64E-02 I. 66E-02 

6.00E+OO 2. 64E-04 S.93E-03 6.19E-03 

7.00E+00 2.S8E-04 2.14E-03 2.40E-03 

8.00E+OO 2.S3E-04 7. 72E-04 1.02E-03 

9.00E+00 2. 47E-04 2. 78E-04 5.2SE-04 

1.00E+Ol 2. 42E-04 1.00E-04 3. 42E-04 

2.00E+OI 1.9SE-04 O.OOE+OO 1.9SE-04 

3.00E+Ol 1. 57E-04 O.OOE+OO 1. S7E-04 

4.00E+Ol 1. 27E-04 O.OOE+OO 1.27E-04 

S.OOE+Ol 1.02E-04 O.OOE+OO 1.02E-04 

6.00E+OI 8.2SE-OS O.OOE+OO 8.2SE-OS 

7.00E+Ol 6.6SE-OS O.OOE+OO 6.6SE-05 

8.00E+Ol S.36E-OS O.OOE+OO 5. 36E-DS 

9.00E+Ol 4. 32E-OS O.OOE+OO 4. 32E-OS 

1.00E+02 3. 49E-OS O.OOE+OO 3. 49E-05 

2.00E+02 4.0SE-06 O.OOE+OO . 4.0SE-06 

3.00E+02 4.7lE-07 O.OOE+OO 4.7lE-07 

4.00E+02 S.47E-08 O.OOE+OO S.47E-08 

B-604 
INGESTION f 1- 3.00£-04 BALFLIFE- 3.25E+Ol DAYS CEllIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUHULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol O.OOE+OO 5. 94E-04 

2.00E-Ol O.OOE+OO 5. 74E-03 

3.00E-Ol O.OOE+OO 1. 88E-02 

4.00E-Ol . O.OOE+OO 4.04E-02 

5.00E-Ol O.OOE+OO 6. 96E-02 

6.00E-ol O.OOE+OO 1.05E-ol 

7.00E-Ol O.OOE+OO 1.45E-Ol 

8.00E-Ol O.OOE+OO 1.87E-Ol 

9.00E-Ol O.OOE+OO 2. 32E-Ol 

1.00E+00 O.OOE+OO O.OOE+OO 2. 76E-Ol 2. 76E-ol 

2.00E+00 O.OOE+OO O.OOE+OO 3. 73E-01 6.43E-Ol 

3.00E+00 O.OOE+OO O.OOE+OO 1. 85E-Ol 8. 14E-Ol 

4.00E+00 O.OOE+OO O.OOE+OO 7. 47E-02 8. 72E-Ol 

5.00E+00 O.OOE+OO O.OOE+OO 2. 82E-02 8.82E-Ol 

6.00E+00 O.OOE+OO O.OOE+OO 1.04E-02 8. 74E-Ol 

7.00E+00 O.OOE+OO O.OOE+OO 3.77E-03 8. 59E-Ol 

8.00E+00 O.OOE+OO O.OOE+OO 1.36E-03 8. 42E-Ol 

9.00E+00 O.OOE+OO O.ooE+OO 4. 92E-04 8. 25E-Ol 

1.0oE+Ol O.OOE+OO O.OOE+OO 1.77E-04 8.08E-Ol 

2.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 6. 53E-Ol 

3.00E+Ol O.OOE+OO O.OOE+OO O.OOE+oo 5.27E-Ol 

4.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 4.26E-Ol 

5.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 3. 44E-Ol 

6.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.78E-Ol 

7.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 2.25E-Ol 

8.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 1.81E-Ol 

9.00E+Ol O.OOE+OO O.OOE+OO O.OOE+oo 1.47E-Ol 

B-605 
INGESTION f l- 3.00K-04 HALFLIFE"'" 2.84K+02 DAYS CERIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 8.9SE-OS 9. 99E-Ol 9. 99E-Ol 

2.00E-OI 1.80E-04 9.93E-Ol 9. 94E-OI 

3.00E-Ol 2. 34E-04 9.80E-Ol 9.80E-OI 

4.00E-Ol 2. 63E-04 9.S7E-Ol 9.S7E-Ol 

S.OOE-OI 2.80E-04 9.27E-0l 9.27E-Ol 

6.00E-Ol 2. 89E-04 8.90E-Ol 8.90E-OI 

7.00E-Ol 2. 93E-04 8.49E-OI 8. 49E-OI 

8.00E-Ol 2. 96E-04 8.04E-Ol 8.0SE-Ol 

9.00E-Ol 2. 98E-04 7. S8E-Ol 7. S9E-Ol 

1.OOE+OO 2. 98E-04 7.lIE-Ol 7.l2E-Ol 

2.00E+OO 2. 98E-04 3.22E-Ol 3. 22E-Ol 

3.00E+OO 2. 98E-04 1.28E-Ol 1. 28E-Ol 

4.00E+OO 2. 97E-04 4.84E-02 4. 87E-02 

S.OOE+OO 2. 96E-04 1.80E-02 1. 83E-02 

6.00E+OO 2.9SE-04 6. 64E-03 6. 94E-03 

7.00E+OO 2.9SE-04 2.44E-03 2. 74E-03 

8.00E+OO 2. 94E-04 8. 98E-04 1.19E-03 

9.00E+OO 2. 93E-04 3.30E-04 6. 23E-04 

1.OOE+Ol 2. 92E-04 1.2lE-04 4.l3E-04 

2.00E+Ol 2.8SE-04 O.OOE+OO 2. 85E-04 

3.00E+Ol 2.77E-04 O.OOE+OO 2.77E 

4.00E+Ol 2.70E-04 O.OOE+OO 2. 

S.OOE+Ol 2. 63E-04 O.OOE+OO 2.63E 

6.00E+Ol 2.S6E-04 O.OOE+OO 2. S6E-O/. 

7.00E+Ol 2. 49E-04 O.OOE+OO 2.49E-04 

8.00E+Ol 2. 43E-04 O.OOE+OO 2. 43E-04 

9.00E+Ol 2. 37E-04 O.OOE+OO 2. 37E-04 

1.OOE+02 2.30E-04 O.OOE+OO 2.30E-04 

2.00E+02 1.77E-04 O.OOE+OO I.77E-04 

3.00E+02 1. 36E-04 O.OOE+OO 1. 36E-04 

4.00E+02 I.OSE-04 O.OOE+OO I.05E-04 

S.OOE+02 8.03E-OS O.OOE+OO 8.03E-05 

6.00E+02 6.l7E-OS O.OOE+OO 6.l7E-OS 

7.00E+02 4. 74E-OS O.OOE+OO 4. 74E-05 

8.00E+02 3. 64E-OS O.OOE+OO 3. 64E-05 

9.00E+02 2.80E-05 O.OOE+OO 2.80E-05 

I.OOE+03 2.15E-OS O.OOE+OO 2.l5E-05 

2.00E+03 1. 54E-06 O.OOE+OO 1. 54E-06 

3.00E+03 1. IOE-07 O.OOE+OO 1.lOE-07 

B-606 
IHGESTIOB f 1- 3.00E-04 IlALFLIFE- 2.84E+02 DAYS CERIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOllR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol O.OOE+OO 5.95E-04 

2.00E-Ol O.OOE+OO 5. 76E-03 

3.00E-Ol O.OOE+OO 1.89E-02 

4.00E-Ol O.OOE+OO 4.07E-02 

5.00E-Ol O.OOE+OO 7.03E-02 

6.00E-01 O.OOE+OO 1.06E-Ol 

7.00E-Ol O.OOE+OO 1.47E-0l 

8.00E-Ol O.OOE+OO 1.90E-Ol 

9.00E-Ol O.OOE+OO 2. 35E-0l 

1.OOE+OO O.OOE+OO O.OOE+OO 2. 82E-Ol 2. 82E-Ol 

2.00E+OO O.OOE+OO O.OOE+OO 3.87E-Ol 6. 68E-Ol 

3.00E+OO O.OOE+OO O.OOE+OO 1. 95E-Ol 8. 62E-Ol 

4.00E+OO O.OOE+OO O.OOE+OO 8.06E-02 9.40E-Ol 

5.00E+OO O.OOE+OO O.OOE+OO 3.lOE-02 9. 69E-Ol 

6.00E+OO O.OOE+OO O.OOE+OO 1.16E-02 9.78E-Ol 

7.00E+OO O.OOE+OO O.OOE+OO 4.31E-03 9.80E-Ol 

8.00E+OO O.OOE+OO O.OOE+OO 1.59E-03 9.79E-0l 

9.00E+OO O.OOE+OO O.OOE+OO 5. 83E-04 9. 78E-Ol 

1.OOE+Ol O.OOE+OO O.OOE+OO 2.14E-04 9. 75E-Ol 

2.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 9. 52E-Ol 

3.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 9.29E-Ol 

4.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 9.07E-01 

5.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 8. 85E-Ol 

6.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 8. 64E-Ol 

7.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 8. 43E-0l 

8.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 8. 23E-Ol 

9.00E+Ol O.OOE+OO O.OOE+OO O.OOE+OO 8.03E-Ol 

1.OOE+02 O.OOE+OO O.OOE+OO O.QOE+OO 7. 83E-Ol 

2.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 6.14E-Ol 

3.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 4.81E-Ol 

4.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 3.77E-01 

5.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 95E-Ol 

6.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 2. 32E-Ol 

7.00E+02 O.OOE+OO O.OOE+OO O.OOE+OO 1.8IE-Ol- , -

: ..; 

B-607 
INGESTION f 1- 3.ooE-04 STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 8. 86E-05 9.99E-OI 9.99E-0l 

2.00E-OI I. 76E-04 9. 94E-OI 9. 94E-OI 

3.00E-OI 2. 26E-04 9.80E-OI 9.8IE-OI 

4.00E-OI 2.5IE-04 9. 58E-Ol 9. 58E-OI 

5.00E-OI 2. 64E-04 9. 28E-OI 9. 28E-OI 

6.00E-OI 2.70E-04 8.9IE-OI 8. 92E-Ol 

7.00E-Ol 2.72E-04 8.50E-Ol 8.51E-OI 

8.00E-Ol 2. 73E-04 8.06E-Ol 8.06E-ol 

9.00E-OI 2. 73E-04 7.60E-Ol 7.60E-OI 

1.OOE+OO 2. 72E-04 7. 13E-Ol 7. 13E-Ol 

2.00E+OO 2. 68E-04 3.24E-Ol 3. 24E-Ol 

3.00E+OO 2. 67E-04 1. 29E-Ol 1.29E-Ol 

4.00E+OO 2. 66E-04 4. 89E-02 4.91E-02 

5.00E+OO 2. 66E-04 1. 82E-02 I. 85E-02 

6.00E+OO 2. 65E-04 6. 74E-03 7.0lE-03 

7.00E+OO 2. 64E-04 2. 49E-03 2. 75E-03 

8.00E+OO 2. 63E-04 9.l5E-04 1.18E-03 

9.00E+OO 2. 63E-04 3. 37E-04 6.00E-04 

1.OOE+Ol 2. 62E-04 I. 24E-04 3. 86E-04 

2.00E+Ol 2. 58E-04 O.OOE+OO 2. 58E-04 

3.00E+OI 2. 55E-04 O.OOE+OO 2.55E-04 

4.00E+Ol 2. 54E-04 O.OOE+OO 2. 54E-04 

5.00E+OI 2. 53E-04 O.OOE+OO 2.53E-04 

6.00E+Ol 2. 52E-04 O.OOE+OO 2. 52E-04 

7.00E+Ol 2. 52E-04 O.OOE+OO 2.52E-04 

8.00E+Ol 2.5lE-04 O.OOE+OO 2.5lE-04 

9.00E+OI 2.5lE-04 O.OOE+OO 2.5lE-04 

1.OOE+02 2.50E-04 O.OOE+OO 2.50E-04 

2.00E+02 2. 45E-04 O.OOE+OO 2. 45E-04 

3.00E+02 2.40E-04 O.OOE+OO 2.40E-04 

4.00E+02 2.36E-04 O.OOE+OO 2. 36E-04 

5.00E+02 2. 31E-04 O.OOE+OO 2.3lE-04 

6.00E+02 2. 26E-04 O.OOE+OO 2. 26E-04 

7.00E+02 2. 22E-04 O.OOE+OO 2. 22E-04 

8.00E+02 2.l8E-04 O.OOE+OO 2. 18E-04 

9.00E+02 2. 13E-04 O.OOE+OO 2.l3E-04 

1.OOE+03 2.09E-04 O.OOE+OO 2.09E-04 

2.00E+03 1.72E-04 O.OOE+OO 1.72E-04 

3.00E+03 1.4lE-04 O.OOE+OO 1.41E-04 

4~OOE+03 1. 16E-04 O.OOE+OO 1.16E-04 

5.00E+03 9. 48E-05 O.OOE+OO 9. 48E-05 

7.00E+03 6. 38E-05 O.OOE+OO 6. 38E-05 

8.00E+03 5.l3E-05 O.OOE+OO 5. 23E-05 

9.00E+03 4. 29E-05 O.OOE+OO 4. 29E-05 

1.OOE+04 3. 52E-05 O.OOE+OO 3.52E-05 

2.00E+04 4. 86E-06 O.OOE+OO 4. 86E-06 

B-608 
INGESTIOR £1- 3.008-04 STABLE PRASEODYMIUM 141 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 9. 65E-07 6.10E-04 

2.00E-OI 4.18E-06 5.901!:-O3 

3.00E-OI B.37E-06 I. 94E-02 

4.00E-OI 1.2SE-05 4.16E-02 

S.OOE-OI I. 63E-05 7.IBE-02 

6.00E-OI I. 94E-OS I.OBE-OI 

7.00E-OI 2.20E-OS I. 49E-OI 

8.00E-OI 2.40E-OS I. 94E-OI 

9.00E-OI 2.S7E-OS 2.40E-OI 

I.OOE+OO 2.70E-05 2.70E-OS 2.B6E-OI 2.B6E-OI 

2.00E+OO 4. 62E-06 3.16E-05 3.90E-OI 6.76E-0l 

3.00E+OO 1.17E-06 3.2BE-OS I. 95E-OI B.71E-OI 

4.00E+OO B.93E-07 3. 37E-OS 7.9BE-02 9.SIE-0l 

S.OOE+OO B.24E-07 3. 45E-05 3.07E-02 9.BIE-OI 

6.00E+OO 7.71E-07 3.S3E-OS 1.ISE-02 9. 93E-OI , 

7.00E+OO 7.23E-07 3.60E-OS 4. 26E-03 9.97E-OI 

B.OOE+OO 6.7BE-07 3. 67E-OS I.S7E-03 9. 99E-0l 

9.00E+OO 6. 36E-07 3. 73E-OS S.79E-04 9. 99E-OI 

I.OOE+OI S.97E-07 3. 79E-OS 2.13E-04 I.OOE+OO 

2.00E+OI 3. 23E-07 4. 22E-05 O.OOE+OO I.OOE+OO 

3.00E+OI I.B7E-07 4. 46E-OS O.OOE+OO 1.OOE+OO 

4.00E+OI 1.IBE-07 4.60E-OS O.OOE+OO I.OOE+OO 

5.00E+Ol B.42E-OB 4.70E-05 O.OOE+OO 1.OOE+OO 

6.00E+OI 6.70E-OB 4.7BE-OS O.OOE+OO I.OOE+OO 

7.00E+OI S.B3E-OB 4.B4E-OS O.OOE+OO I.OOE+OO 

B.OOE+Ol S.40E-OB 4.B9E-05 O.OOE+OO I.OOE+OO 

9.00E+OI S.17E-08 4.9SE-05 O.OOE+OO I.OOE+OO 

1.00E+02 S.06E-OB S.OOE-OS O.OOE+OO I.OOE+OO 

2.00E+02 4. BSE-OB 5. 49E-OS O.OOE+OO 1.00E+OO 

3.00E+02 4. 76E-OB S.97E-05 O.OOE+OO 1.OOE+OO 

4.00E+02 4. 67E-OB 6. 44E-OS O.OOE+OO 1.00E+OO 

S.OOE+02 4.S7E-OB . 6.90E-OS O.OOE+OO 1.00E+OO 

6.00E+02 4.4BE-OB 7. 36E-OS O.OOE+OO 1.00E+OO 

7.00E+02 4.40E-OB 7. BOE-OS O.OOE+OO 1.00E+OO ";- , B.OOE+02 4. 31E-OB B.23E-OS O.OOE+OO I.OOE+OO 

9.00E+02 4. 23E-OB B.66E-OS O.OOE+OO 1.00E+OO 

1.00E+03 4. 14E-OB 9.0BE-OS O.OOE+OO 1.00E+OO 

2.00E+03 3.40E-OB 1.2BE-04 O.OOE+OO 1.OOE+OO 

3.00E+03 2. 79E-OB 1. S9E-04 O.OOE+OO I.OOE+OO 

4.00E+03 2. 29E-OB I.B4E-04 O.OOE+OO 1.OOE+OO 

S.OOE+03 1.BBE-OB 2.0SE-04 O.OOE+OO 1.00E+OO 

6.00E+03 1. 54E-OB 2. 22E-04 O.OOE+OO 1.OOE+OO 

7.00E+03 1. 26E-OB 2. 36E-04 O.OOE+OO 1.00E+OO 

B.OOE+03 1.04E-OB 2.4BE-04 O.OOE+OO 1.OOE+OO 

B-609 
INGESTION f l- 3.00E-04 STABLE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 8. 86E-OS 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 76E-04 9. 94E-Ol 9.94E-Ol 

3.00E-Ol 2. 26E-04 9.80E-0l 9. SlE-Ol 

4.00E-Ol 2.SlE-04 9.S8E-Ol 9.S8E-Ol 

S.OOE-Ol 2. 64E-04 9. 28l!:-Ol 9. 28E-Ol 

6.00E-Ol 2.70E-04 8.9lE-Ol 8. 92E-Ol 

7.00E-Ol 2. 73E-04 8.S0E-Ol 8.SlE-Ol 

8.00E:"'Ol 2. 73E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 2.73E-04 7.60E-Ol 7.60E-Ol 

1.OOE+OO 2. 73E-04 7.13E-Ol 7.l3E-Ol 

2.00E+OO 2.70E-04 3.24E-Ol 3. 24E-Ol 

3.00E+OO 2.70E-04 1. 29E-Ol 1.29E-Ol 

4.00E+OO 2.70E-04 4.89E-02 4.9lE-02 

S.OOE+OO 2.70E';"04 1. 82E":02 1. 8SE-02· 

6.00E+OO 2.70E-04 6. 74E-03 7.0lE-03 

7.00E+OO 2.70E-04 2.49E-03 2. 76E-03 

8.00E+OO 2.70E-04 9.lSE-04 1.19E-03 

9.00E+OO 2.70E-04 3. 37E-04 6.06E-04 

1.OOE+Ol 2.69E-04 1.24E-04 3. 93E-04 

2.00E+Ol 2. 69E-04 O.OOE+OO 2. 69E-04 

3.00E+Ol 2.68E-04 O.OOE+OO 2.68E-04 

4.00E+Ol 2. 68E-04 O.OOE+OO 2. 68E-04 

S.OOE+Ol 2. 67E-04 O.OOE+OO 2. 67E-04 

6.00E+Ol 2. 67E-04 O.OOE+OO 2. 67E-04 

7.00E+Ol 2. 66E-04 O.OOE+OO 2.66E-04 

8.00E+Ol 2. 66E-04 O.OOE+OO 2. 66E-04 

9.00E+Ol 2.6SE-04 O.OOE+OO 2.6SE-04 

l.OOE+02 2. 65E-04 O.OOE+OO 2.6SE-04 

2.00E+02 2.60E-04 O.OOE+OO 2.60E-04 

3.00E+02 2.S4E-04 O.OOE+OO 2.S4E-04 

4.00E+02 2. 49E-04 O.OOE+OO 2. 49E-04 

S.OOE+02 2. 45E-04 O.OOE+OO 2.4SE-04 

6.00E+02 2.40E-04 O.OOE+OO 2.40E-04 

7.00E+02 2.3SE-04 O.OOE+OO 2.3SE-04 

8.00E+02 2.30E-04 O.OOE+OO 2.30E-04 

9.00E+02 2. 26E-04 O.OOE+OO 2. 26E-04 

l.OOE+03 2.22E-04 O.OOE+OO 2. 22E-04 

2.00E+03 1. 82E-04 O.OOE+OO l.82E-04 

3.00E+03 1.49E-04 O.OOE+OO 1.49E-04 

4.00E+03 1. 22E-04 O.OOE+OO l.22E-04 

S.OOE+03 1.OOE-04 O.OOE+OO 1.00E-04 

7.00E+03 6.7SE-OS O.OOE+OO 6.7SE-OS 

8.00E+03 . S.54E-OS O.OOE+OO S.S4E-OS 

9.00E+03 4.S4E-OS O.OOE+OO 4.S4E-OS 

1.OOE+04 3. 73E-OS O.OOE+OO 3.73E-OS 

2.00E+04 5.lSE-06 O.OOE+OO 5.lSE-06 

B-6l0 
INGESTION f.- 3.00£-04 STABIE NEODYMIUM 144 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

i.OOE-OI 9. 52E-07 6. IOE-04 

2.00E-OI 4. 12E-06 5.90E-03 

3.00E-Ol S.23E-06 1.94E-02 

4.00E-Ol 1. 23E-05 4.16E-02 

5.00E-Ol I.60E-05 7. ISE-02 

6.00E-OI I.90E-05 I.OSE-OI 

7.00E-OI 2.15E-05 1. 49E-Ol 

S.OOE-OI 2. 34E-D5 1. 94E-Ol 

9.00E-Ol 2.50E-05 2.40E-OI 

1.00E+OO 2. 62E-05 2. 62E-05 2.S6E-OI 2.S6E-OI 

2.00E+OO 3. 67E-06 2.9SE-05 3.90E-OI 6. 76E-Ol 

3.00E+OO 2.S5E-07 3.01E-05 1. 95E-OI S.71E-OI 

4.00E+OO 6. SOE-OS 3.02E-05 7.9SE-02 9.51E-Ol 

5.00E+OO 5. 43E-OS 3.03E-05 3.07E-02 9.S1E-OI 

6.00E+OO 5. 35E-OS 3.03E-05 I.I5E-02 9. 93E-OI 

7.00E+OO 5. 34E-OS 3.04E-05 4. 26E-03 9. 97E-Ol 

S.OOE+OO 5. 34E-OS 3.04E-05 1. 57E-03 9. 99E-Ol 

9.00E+OO 5. 34E-OS 3.05E-05 5. 79E-04 9. 99E-OI 

I.OOE+Ol 5. 34E-OS 3.05E-05 2.13E-04 I.OOE+OO 

2.00E+OI 5. 33E-OS 3.IIE-05 O.OOE+OO I.OOE+OO 

3.00E+OI 5. 32E-OS 3.16E-05 O.OOE+OO 1.00E+OO 

4.00E+OI 5.30E-OS 3. 21E-05 O.OOE+OO I.OOE+OO 

5.00E+OI 5. 29E-OS 3. 26E-05 O.OOE+OO 1.00E+OO 

6.00E+OI 5.2SE-OS 3. 32E-05 O.OOE+OO 1.00E+OO 

7.00E+OI 5. 27E-OS 3.37E-05 O.OOE+OO I.OOE+OO 

S.OOE+Ol 5. 26E-OS 3. 42E-05 O.OOE+OO 1.00E+OO 

9.00E+OI 5. 25E-OS 3.4SE-05 O.OOE+OO I.OOE+OO 

1.00E+02 5. 24E-OS 3. 53E-05 O.OOE+OO I.OOE+OO 

2.00E+02 5.14E-OS 4.05E-05 O.OOE+OO I.OOE+OO 

3.00E+02 5.04E-OS 4. 56E-05 O.OOE+OO I.OOE+OO 

4.00E+02 4.94E-OS 5.05E-05 O.OOE+OO I.OOE+OO 

5.00E+02 4. S4E-OS 5. 54E-05 O.OOE+OO. I.OOE+OO 

6.00E+02 4. 75E-OS 6.02E-05 O.OOE+OO I.OOE+OO 

7.00E+02 4.65E-DS .' ,'. 6. 49E-05 O.OOE+OO I.OOE+OO ' . S.OOE+02 4. 56E-OS 6.95E-05 O.OOE+OO I.OOE+OO . 9.00E+02 4. 47E-OS 7.4IE-05 O.OOE+OO I.OOE+OO 

I.OOE+03 4. 39E-OS 7.85E-05 O.OOE+OO I.OOE+OO 

2.00E+03 3.60E-08 1. 18E-04 O.OOE+OO 1.00E+OO 

3.00E+03 2. 95E-08 I.51E-04 O.OOE+OO I.OOE+OO 

4.00E+03 2. 42E-08 1.7SE-04 O.OOE+OO I.OOE+OO 

5.00E+03 1. 99E-08 2.00E-04 O.OOE+OO 1.00E+OO 

6.00E+03 1. 63E-08 2.1SE-04 O.OOE+OO 1.00E+OO 

7.00E+03 1. 34E-08 2.32E-04 O.OOE+OO 1.00E+OO 

S.OOE+03 I.lOE-08 2. 45E-04 O.OOE+OO 1.00E+OO 

B-611 
INGESTION f1= 3.00£-04 IlALFLlI'E= 9.58£+02 DAYS P.ROHETHIUH 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 8. 86E-OS 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 76E-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 2. 26E-04 9.80E-Ol 9.80E-Ol 

4.00E-Ol 2.5lE-04 9. 58E-Ol 9.S8E-Ol 

S.OOE-Ol 2. 64E-04 9. 28E-Ol 9. 28E-Ol 

6.00E-Ol 2.70E-04 8.9lE-Ol 8.9lE-Ol 

7.00E-Ol 2.72E-04 8.S0E-Ol 8.S0E-Ol 

8.00E-Ol 2. 73E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 2. 73E-04 7.S9E-Ol 7.60E-Ol 

1.OOE+OO 2. 73E-04 7.13E-Ol 7.13E-Ol 

2.00E+OO 2.70E-04 3.23E-Ol 3. 23E-Ol 

3.00E+OO 2. 69E-04 1.28E-Ol 1.29E-Ol 

4.00E+OO 2. 69E-04 4. 87E-02 4.90E-02 

5.00E+OO 2. 69E-04 1. 82E-02 1. 84E-02 

6.00E+OO 2. 69E-04 6.7lE-03 6. 98E-03 

7.00E+OO 2. 68E-04 2. 47E-03 2. 74E-03 

8.00E+OO 2. 68E-04 9.l0E-04 1.18E-03 

9.00E+OO 2. 68E-04 3. 35E-04 6.03E-04 

1.OOE+Ol 2. 68E-04 1. 23E-04 3.9lE-04 

2.00E+Ol 2. 65E-04 O.OOE+OO 2.6SE-04 

3.00E+Ol 2.63E-04 O.OOE+OO 2.6 

4.00E+Ol 2.60E-04 O.OOE+OO 2. 

S.OCE+Ol 2. 58E-04 O.OOE+OO 2. 

6.00E+Ol 2.S5E-04 O.OOE+OO 2.SSE-04 

7.00E+Ol 2.S3E-04 O.OOE+OO 2.S3E-04 

8.00E+Ol 2.SlE-04 O.OOE+OO 2.SlE-04 

9.00E+Ol 2. 49E-04 O.OOE+OO 2. 49E-04 

1.OOE+02 2. 46E-04 O.OOE+OO 2. 46E-04 

2.00E+02 2.2SE-04 O.OOE+OO 2.2SE-04 

3.00E+02 2.0SE-04 O.OOE+OO 2.0SE-04 

4.00E+02 1. 87E-04 O.OOE+OO 1.87E-04 

5.00E+02 1.70E-04 O.OOE+OO 1.70E-04 

6.00E+02 1. SSE-04 O.OOE+OO 1. S5E-04 

7.00E+02 1. 42E-04 O.OOE+OO 1. 42E-04 

8.00E+02 1. 29E-04 O.OOE+OO 1. 29E-04 

9.00E+02 1.18E-04 O.OOE+OO 1.18E-04 '. ; 1.OOE+03 1.07E-04 O.OOE+OO 1.07E-04 

2.00E+03 4. 27E-05 O.OOE+OO 4. 27E-OS 

3.00E+03 1.70E-OS O.OOE+OO 1.70E-OS 

4.00E+03 6. 76E-06 O.OOE+OO 6. 76E-06 

S.OOE+03 2. 69E-06 O.OOE+OO 2. 69E-06 

6.00E+03 1.07E-06 O.OOE+OO 1.07E-06 

7.00E+03 4.2SE-07 O.OOE+OO 4. 25E-07 

8.00E+03 1. 69E-07 O.OOE+OO 1.69E-07 

9.00E+03 6. 73E-08 O.OOE+OO 6.73E-08 

1.00E+04 2. 68E-08 O.OOE+OO 2. 68E-O 

B-612 
INGESTION f l- 3.00£-04 BALl'LIPE'" 9.58£+02 DAYS PROMETHIUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------

SYSTEMIC NON-SYSTEMIC 

--------------- --------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 9. 52E-07 6.10E-04 

2.00E-Ol' 4.12E-06 5.90E-03 

3.00E-Ol 8. 23E-06 1.93E-02 

4.00E-OI I. 23E-OS 4.16E-02 

5.00E-OI I. 59E-05 7.17E-02 . 6.00E-OI 1.90E-05 I.08E-Ol 

7.00E-Ol 2.ISE-05 I.49E-Ol 

8.00E-OI 2. 34E-05 1. 94E-Ol 

9.00E-OI 2.S0E-05 2.40E-Ol 

l.OOE+OO 2. 62E-OS 2. 62E-05 2. 86E-OI 2. 86E-Ol 

2.00E+OO 3. 66E-06 2. 98E-05 3.89E-OI 6. 75E-Ol 

3.00E+OO 2. 84E-07 3. OlE-OS 1. 94E-OI 8. 69E-Ol 

4.00E+OO 6. 78E-08 3. OlE-OS 7.96E-02 9. 48E-Ol 

S.OOE+OO S.41E-08 3. OlE-05 3.0SE-02 9. 78E-OI 

6.00E+OO 5. 32E-08 3.02E-05 l.14E-02 9. 89E-Ol 

7.00E+OO S.31E-08 3.02E-OS 4. 23E-03 9. 92E-OI 

8.00E+OO 5.3IE-08 3.02E-05 l.S6E-03 9. 93E-Ol 

9.00E+OO 5.30E-08 3.03E-OS 5. 75E-04 9. 93E-OI 

I.OOE+OI 5.30E-08 3.03E-05 2.11E-04 9.92E-Ol 

2.00E+OI 5. 25E-08 3.06E-05 O.OOE+OO 9.85E-OI 

3.00E+OI 5.20E-08 3.09E-05 O.OOE+OO 9.78E-Ol 

4.00E+OI 5.l5E-08 3.12E-OS . O.OOE+OO 9.71E-Ol 

5.00E+Ol S.llE-08 3.ISE-05 O.OOE+OO 9. 64E-ol 

6.00E+Ol 5.06E-08 3.18E-05 O.OOE+OO 9.57E-Ol 

7.00E+OI 5.01E-08 3.20E-05 O.OOE+OO 9.50E-OI 

8.00E+OI 4. 97E-08 3. 23E-oS O.OOE+OO 9.43E-Ol 

9.00E+OI 4. 92E-08 3. 26E-OS O.OOE+OO 9. 37E-ol 

I.OOE+02 4.88E~08 3. 28E-05 O.OOE+OO 9.30E-Ol 

2.00E+02 4.4SE-08 3.50E-05 O.OOE+OO 8. 65E-OI 

3.00E+02 4.05E-08 3. 67E-05 O.OOE+OO 8.05E-OI 

4.00E+02 3.70E-08 3. 78E-05 O.OOE+OO 7. 48E-OI 

5.00E+02 3. 37E-08 3. 86E-OS O.OOE+OO 6. 96E-Ol 

6.00E+02 3.08E-08 3.90E-05 O.OOE+OO 6.48E-Ol 

7.00E+02 2.80E-08 3.91E-05 O.OOE+OO 6.02E-Ol . . ~ 8.00E+02 2. 56E-08 3.90E-OS O.OOE+OO 5.60E-Ol ~; .",::. ~, .' 9.00E+02 2. 33E-08 3. 86E-05 O.OOE+OO 5.2IE-Ol 

1.00E+03 2.13E-08 3.81E-05 O.OOE+OO 4.85E-0l 

B-6l3 
INGESTION £1= 3.00E-04 BALFLIFE- 3.87E+13 DAYS SAlWUUH 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 8. 86E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 76E-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 2. 26E-04 9.80E-Ol 9. 8 lE'-O 1 

4.00E-Ol 2.51E-04 9. 58E-Ol 9. 58E-Ol 

5.00E-Ol 2. 64E-04 9.28E-Ol 9. 28E-Ol 

6.00E-Ol 2.70E-04 8.91E-Ol 8. 92E-Ol 

.7.00E-0l 2. 73E-04 8.50E-Ol 8.51E-Ol 

8.00E-Ol 2. 73E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 2. 73E-04 7.60E-Ol 7.60E-Ol 

1.OOE+OO 2. 73E-04 7.13E-Ol 7.13E-Ol 

2.00E+OO 2.70E-04 3. 24E-Ol 3. 24E-Ol 

3.00E+OO 2.70E-04 1. 29E-ol 1. 29E-Ol 

4.00E+OO 2.70E-04 4.89E-02 4. 91E-02 

5.00E+OO 2.70E-04 1. 82E-02 1. 85E-02 

6.00E+OO 2.70E-04 6. 74E-03 7.01E-03 

7.00E+OO 2.70E-04 2. 49E-03 2. 76E-03 

8.00E+OO 2.70E-04 9. 15E-04 1. 19E-03 

9.00E+OO 2.70E-04 3. 37E-04 6.06E-04 

1.00E+Ol 2. 69E-04 1. 24E-04 3. 93E-04 

2.00E+Ol 2. 69E-04 O.OOE+OO 2.6?E-04 

3.00E+Ol 2. 68E-04 O.OOE+OO 2. 68E-04 

4.00E+Ol 2. 68E-04 O.OOE+OO 2. 68E-04 

S.OOE+Ol 2. 67E-04 O.OOE+OO 2. 67E-04 

6.00E+Ol 2. 67E-04 O.OOE+OO 2. 67E-04 

7.00E+Ol 2. 66E-04 O.OOE+OO ~.66E-04 

8.00E+Ol 2. 66E-04 O.OOE+OO 2. 66E-04 

9.00E+Ol 2. 65E-04 O.OOE+OO 2.65E-04 

1.OOE+02 2. 65E-04 O.OOE+OO 2. 65E-04 

2.00E+02 2.60E-04 O.OOE+OO 2.60E-04 

3.00E+02 2. 54E-04 O.OOE+OO 2.S4E-04 

4.00E+02 2. 49E-04 O.OOE+OO 2. 49E-04 

5.00E+02 2. 45E-04 O.OOE+OO 2. 45E-04 

6.00E+02 2.40E-04 O.OOE+OO 2.40E-04 

7.00E+02 2. 35E-04 O.OOE+OO 2. 35E-04 

8.00E+02 2.30E-04 O.OOE+OO 2.30E-04 

9.00E+02 2. 26E-04 O.OOE+OO 2. 26E-04 

1.00E+03 2. 22E-04 O.OOE+OO 2. 22E-04 

2.00E+03 1. 82E-04 O.OOE+OO 1. 82E-04 

3.00E+03 1. 49E-04 O.OOE+OO 1 .. 49E-04 

4.00E+03 1. 22E-04 O.OOE+OO 1. 22E-04 

S.OOE+03 1.OOE-04 O.OOE+OO 1.00E-04 

7.00E+03 6. 75E-05 O.OOE+OO 6. 75E-05 

8.00E+03 5.54E-05 O.OOE+OO 5.54E-05 

9.00E+03 4. 54E-OS O.OOE+OO 4. 54E-05 

1.00E+04 3.73E-OS O.OOE+OO 3. 73E-05 

2.00E+04 5.15E-06 O.OOE+OO S.ISE-06 

B-614 
INGESTION £1= 3.00E-04 BALFLlFE= 3.87E+13 DAYS SAKAR.IUM 147 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

, S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 9.S2E-07 6.10E-04 

2.00E-Ol 4. 12E-06 5.90E-03 

3.00E-Ol 8. 23E-06 1.94E-02 

4.00E-Ol 1. 23E-05 4.l6E-02 

5.00E-Ol 1.60E-05 7.lBE-02 

6.00E-Ol 1.90E-05 1.08E-Ol 

7.00E-Ol 2.lSE-05 1.49E-Ol 

B.OOE-01 2. 34E-05 1. 94E-01 

9.00E-01 2.50E-OS 2.40E-01 

1.OOE+OO 2. 62E-OS 2. 62E-OS 2.B6E-01 2.B6E-01 

2.00E+OO 3. 67E-06 2.98E-OS 3.90E-Ol 6. 76E-01 

3.00E+OO 2. BSE-07 3.01E-OS 1.9SE-01 B.71E-01 

4.00E+OO 6.BOE-OB 3.02E-OS 7.98E-02 9.51E-Ol 

S.OOE+OO 5.43E-08 3.03E-05 3.07E-02 9.B1E-01 

6.00E+OO S.35E-OB 3.03E-05 1. 15E-02 9. 93E-01 

7.00E+OO 5. 34E-OB 3.04E-05 4. 26E-03 9. 97E-01 

B.OOE+OO 5.34E-08 3.04E-05 1.57E-03 9. 99E-01 

9.00E+OO S.34E-OB 3.05E-OS 5. 79E-04 9.99E-01 

1.00E+Ol S.34E-OB 3.0SE-OS 2.13E-04 1.00E+OO 

2.00E+Ol S.33E-OB 3.11E-OS O.OOE+OO 1.00E+OO 

3.00E+Ol S.32E-08 3.16E-OS O.OOE+OO 1.00E+OO 

4.00E+Ol S.30E-OB 3.21E-OS O.OOE+OO 1.00E+OO 

S.OOE+Ol S.29E-OB 3.26E-05 O.OOE+OO 1.OOE+OO 

6.00E+Ol 5.2BE-OB 3. 32E-OS O.OOE+OO 1.00E+OO 

7.00E+Ol 5. 27E-OB 3. 37E-05 O.OOE+OO 1.OOE+OO 

8.00E+01 5. 26E-OB 3. 42E-OS O.OOE+OO 1.OOE+OO 

9.00E+01 S.2SE-OB 3.48E-OS O.OOE+OO 1.00E+OO 

1.OOE+02 S.24E-08 3.S3E-OS O.OOE+OO 1.00E+OO 

2.00E+02 5. 14E-08 4.05E-OS O.OOE+OO 1.OOE+OO 

3.00E+02 S.04E-OB 4. 56E-05 O.OOE+OO 1.00E+OO 

4.00E+02 4. 94E-OB S.OSE-OS O.OOE+OO 1.00E+OO 

S.OOE+02 4.B4E-08 S.S4E-OS O.OOE+OO 1.00E+OO 

6.00E+02 4.7SE-OB 6.02E-OS O.OOE+OO 1.00E+OO 

7.00E+02 4.6SE-08 6.49E-05 O.OOE+OO 1.00E+OO 

B.OOE+02 4.S6E-OB 6.9SE-OS O.OOE+OO 1.00E+OO 

9.00E+02 4.47E-OB 7.41E-OS O.OOE+OO 1.OOE+OO 

1.00E+03 4. 39E-OB 7. BSE-OS O.OOE+OO 1.00E+OO 

2.00E+03 3.60E-OB 1.lBE-04 O.OOE+OO 1.00E+OO 

3.00E+03 2.9SE-OB 1.51E-04 O.OOE+OO 1.00E+OO 

4.00E+03 2. 42E-OB 1. 78E-04 O.OOE+OO 1.00E+OO 

S.OOE+03 I. 99E-OB 2.00E-04 O.OOE+OO 1.00E+OO 

6.00E+03 I. 63E-OB 2.18E-04 O.OOE+OO I.OOE+OO 

7.00E+03 1. 34E-08 2.32E-04 O.OOE+OO I.OOE+OO 

B.OOE+03 l.lOE-OB 2.45E-04 O.OOE+OO I.OOE+OO 

B-6IS 
INGESTION f1"" 3.00£-04 STABLE SAHAR.IUK 150 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE . -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT ' BODY 

1.00E-Ol 8. 86E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 76E-04 9. 94E-Ol 9.94E-01 

3.00E-01 2. 26E-04 9.80E-01 9.81E-01 

4.00E-01 2. 51E-04 9. 58E-Ol 9. 58E-01 

5.00E-01 2~64E-04 9.28E-01 9. 28E-01 

6.00E-01 2.70E';"04 8.91E-01 8. 92E-01 

7.00E-01 2. 73E-04 8.50E-01 8.51E-01 

8.00E-01 2. 73E-04 8.06E-01 8.06E-01 

9.00E-01 2. 73E-04 7.60E-01 7.60E-01 

1.00E+00 2.73E-04 7. 13E-01 7. 13E-01 

2.00E+00 2.70E-04 3. 24E-01 3. 24E-01 

3.00E+00 2.70E-04 1.29E-01 1. 29E-01 

4.00E+00 2.70E-04 4. 89E-02 4.91E-02 

5.00E+00 2.70E-04 1. 82E-02 1. 85E-02 

6.00E+00 2.70E-04 6. 74E-03 7.01E-03 

7.00E+00 2.70E-04 2. 49E-03 2. 76E-03 

8.00E+00 2.70E-04 9. 15E-04 1. 19E-03 

9.00E+00 2.70E-04 3. 37E-04 6.06E-04 

1.00E+01 2. 69E-04 1.24E-04 3.93E-04 

2.00E+01 2. 69E-04 O.OOE+OO 2. 69E-04 

3.00E+01 2. 68E-04 O.OOE+OO 2.68E-04 

4.00E+01 2. 68E-04 O.OOE+OO 2. 68E-04 

5.00E+01 2. 67E-04 O.OOE+OO 2. 67E-04 

6.00E+01 2.67E-04 O.OOE+OO 2. 67E-04 

7.00E+01 2. 66E-04 O.OOE+OO 2.66E-04 

8.00E+01 2. 66E-04 O.OOE+OO 2. 66E-04 

9.00E+01 2. 65E-04 O.OOE+OO 2. 65E-04 

1.00E+02 2.65E'-(\!" O.OOE+OO 2. 65E-04 

2.00E+02 2.60E-04 O.OOE+OO 2.60E-04 

3.00E+02 2. 54E-04 O.OOE+OO 2. 54E-04 

4.00E+02 2. 49E-04 O.OOE+OO 2. 49E-04 

5.00E+02 2. 45E-04 O.OOE+OO 2. 45E-04 

6.00E+02 2.40E-04 O.OOE+OO 2.40E-04 

7.00E+02 2. 35E-04 O.OOE+OO 2. 35E-04 

8.00E+02 2.30E-04 O.OOE+oo 2.30E-04 

9.00E+02 2. 26E-04 O.OOE+OO 2. 26E-04 

1.00E+03 2. 22E-04 O.OOE+OO 2. 22E-04 

2.00E+03 1. 82E-04 O.OOE+OO 1. 82E-04 

3.00E+03 1. 49E-04 O.OOE+OO 1. 49E-04 

4.00E+03 1. 22E-04 O.OOE+OO 1. 22E-04 

5.00E+03 1.00E-04 O.OOE+OO 1.00E-04 

7.00E+03 6. 75E-05 O.OOE+OO 6. 75E-05 

8.00E+03 5.54E-05 O.OOE+OO 5. 54E-05 

9.00E+03 4. 54E-05 O.OOE+OO 4. 54E-05 

1.00E+04 3. 73E-05 O.OOE+OO 3. 73E-05 

2.00E+04 5. 15E-06 O.OOE+OO 5. 15E-06 

B-616 
INGESTION f l- 3.00E-04 STABLE SAlWUUK1.50 

TIME AFTER FRACTION OF· INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 9. 52E-07 6.l0E-04 

2.00E-Ol 4.l2E-06 5.90E-03 

3.00E-0l S.23E-06 1.94E-02 

4.00E-Ol 1.23E-05 4.l6E-02 

5.00E-Ol 1.60E-05 7.lSE-02 

6.00E-Ol 1.90E-05 1.OSE-Ol 

7.00E-Ol 2.ISE-05 1.49E-Ol 

S.OOE-Ol 2. 34E-05 1.94E-Ol 

9.00E-Ol 2.50E-05 2.40E-Ol 

1.OOE+OO 2. 62E-05 2. 62E-05 2.S6E-Ol 2.S6E-Ol 

2.00E+OO 3. 67E-06 2.9SE-05 3.90E-Ol 6. 76E-Ol 

3.00E+OO 2.S5E-07 3.0lE-OS 1.95E-Ol S.7lE-OI 

4.00E+OO 6.80E-OS 3.02E-05 7.9SE-02 9.5lE-0l 

5.00E+OO S.43E-OS 3.03E-05 3.07E-02 9.SlE-Ol 

6.00E+OO 5.3SE-OS 3.03E-OS 1.15E-02 9. 93E-Ol 

7.00E+OO ·5.34E-OS 3.04E-OS 4. 26E-03 9.97E-Ol . 

S.OOE+OO 5. 34E-OS 3.04E-OS 1. S7E-03 9. 99E-Ol 

9.00E+OO 5. 34E-OS 3.05E-OS S.79E-04 9. 99E-Ol 

1.OOE+Ol 5. 34E-OS 3.0SE-05 2.l3E-04 1.OOE+OO 

2.00E+Ol 5. 33E-OS 3.lIE-05 O.OOE+OO 1.OOE+OO 

3.00E+Ol S.32E-OS 3.l6E-05 O.OOE+OO 1.OOE+OO 

4.00E+OI 5.30E-OS 3.2IE-OS O.OOE+OO 1.OOE+OO 

5.00E+Ol 5. 29E-OS 3. 26E-05 O.OOE+OO 1.OOE+OO 

6.00E+OI 5.2SE-OS 3. 32E-OS O.OOE+OO 1.OOE+OO 

7.00E+OI 5. 27E-OS 3. 37E-05 O.OOE+OO 1.OOE+OO 

S.OOE+Ol 5. 26E-OS 3. 42E-OS O.OOE+OO 1.OOE+OO 

9.00E+Ol S.2SE-08 3.4SE-OS O.OOE+OO 1.OOE+OO 

1.OOE+02 S.24E-08 3.S3E-OS O.OOE+OO 1.OOE+OO 

2.00E+02 S.14E-08 4.0SE-OS O.OOE+OO I.OOE+OO 

3.00E+02 5.04E-08 4.S6E-05 O.OOE+OO I.OOE+OO 

4.00E+02 4. 94E-08 S.05E-05 O.OOE+OO 1.OOE+OO 

S.OOE+02 4.S4E-08 S.54E-OS O.OOE+OO I.OOE+OO 

6.00E+02 4.7SE-08 6.02E-OS O.OOE+OO 1.OOE+OO .. 7.00E+02 4. 65E-OS 6. 49E-OS O.OOE+OO I.OOE+OO , 

S.OOE+02 4.S6E-08 6.9SE-OS O.OOE+OO I.OOE+OO 

9.00E+02 4. 47E-:-08 7.4IE-05 O.OOE+OO I.OOE+OO 

1.OOE+03 4. 39E-08 7.S5E-OS O.OOE+OO 1.OOE+OO 

2.00E+03 3.60E-OS 1.ISE-04 O.OOE+OO 1.00E+OO 

3.00E+03 2.9SE-08 1.SIE-04 O.OOE+OO I.OOE+OO 

4.00E+03 2. 42E-OS 1.7SE-04 O.OOE+OO 1.OOE+OO 

5.00E+03 1.99E-08 2.00E-04 O.OOE+OO 1.00E+OO 

6.00E+03 1. 63E-OS 2.ISE-04 O.OOE+OO 1.00E+OO 

7.00E+03 1. 34E-08 2. 32E-04 O.OOE+OO 1.OOE+OO 

8.00E+03 1.1OE-OS 2.4SE-04 O.OOE+OO 1.OOE+OO 

B-6l7 
INGESTION STABLE 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------

DAYS 

1.00E-01 

2.00E-Ol 

3.00E-Ol 

4.00E-01 

5.00E-01 

6.00E-01 

7.00E-Ol 

8. OOE-O 1 

9.00E-01 

1.00E+00 

2.00E+00 

3.00E+00 

4.00E+00 

5.00E+00 

6.00E+00 

7.00E+00 

8.00E+00 

9.00E+00 

1.00E+Ol 

2.00E+01 

3.00E+01 

4.00E+01 

5.00E+01 

6.00E+01 

7.00E+01 

8.00E+01 

9.00E+01 

1.00E+02 

2.00E+02 

3.00E+02 

4.00E+02 

5.00E+02 

6.00E+02 

7.00E+02 

8.00E+02 

9.00E+02 

1.00E+03 

2.00E+03 

3.00E+03 

4.00E+03 

5.00E+03 

7.00E+03 

8.00E+03 

9.00E+03 

1.00E+04 

2.00E+04 

SYSTEMIC 

ORGANS 

2. 94E-04 

5.82E-04 

7.41E-04 

8.21E-04 

8.58E-04 

8.73E-04 

8.78E-04 

8. 77E~04 

8.75E-04 

8.71E-04 

8.54E-04 

8. 49E-04 

8.46E-04 

8.42E-04 

8.39E-04 

8. 36E-04 

8.34E-04 

8.31E-04 

8. 29E-04 

8. 12E-04 

8.03E-04 

7.98E-04 

7.94E-04 

7.92E-04 

7. 89E-04 

7.88E-04 

7.86E-04 

7.84E-04 

7.69E-04 

7.54E-04 

7.39E-04 

7.25E-04 

7.10E-04 

6.96E-04 

6. 83E-04 

6.69E-04 

6. 56E-04 

5.38E-04 

4. 42E-04 

3. 62E-04 

2. 97E-04 

2.00E-04 

1. 64E-04 

1. 35E-04 

1.1OE-04 

1. 53E-05 

B-618 

GI 

TRACT 

9. 99E-01 

9.93E-01 

9.80E-01 

9. 58E-01 

9.27E-01 

8.91E-01 

8.50E-01 

8.05E-01 

7. 59E-01 

7. 13E-01 

3.23E-01 

1.29E-01 

4.88E-02 

1.82E-02 

6. 74E-03 

2.48E-03 

9. 15E-04 

3. 37E-04 

1. 24E-04 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

O.OOE+OO 

EUROPIUM 151 

TOTAL 

BODY 

9.99E-Ol 

9.94E-01 

9.81E-01 

9. 58E-01 

9. 28E-01 

8. 92E-01 

8.51E-01 

8.06E-01 

7.60E-01 

7. 14E-01 

3.24E-01 

1.29E-01 

4.97E-02 

1.90E-02 

7.57E-03 

3. 32E-03 

1. 75E-03 

1.17E-03 

9.53E-04 

8. 12E-04 

8.03E7.98E 

7.94E 

7. 92E-04 

7. 89E-04 

7.88E-04 

7.86E-04 

7. 84E-04 

7. 69E-04 

7. 54E-04 

7.39E-04 

7.25E-04 

7.10E-04 

6. 96E-04 

6. 83E-04 

6.69E-04 

6. 56E-04 

5. 38E-04 

4.42E-04 

3. 62E-04 

2. 97E-04 

2.00E-04 

1.64E-04 

1.35E-04 

1.10E-04 

1. 53E-05 
INGESTION fl= 1.00E-03 STABLE EUROPIUM 151 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4.50E-06 6.IOE-04 

2.00E-Ol 1. 95E-05 5.90E-03 

3.00E-Ol 3.90E-05 1.93E-02 

4.00E-Ol 5.84E-05 4. 16E-02 

5.00E-01 7.57E-05 7. 17E-02 

6.00E-Ol 9.03E-05 1.08E-01 

7.00E-Ol 1.02E-04 1.49E-01 

8.00E-Ol 1. 12E-04 1. 94E-Ol 

9.00E-01 1. 19E-04 2.40E-Ol 

1.00E+00 1. 25E-04 1. 25E-04 2.86E-Ol 2. 86E-Ol 

2.00E+00 2.08E-05 1. 46E-04 3. 89E-Ol 6. 76E-Ol 

3.00E+00 4. 79E-06 1. 51E-04 1.95E-01 8.70E-01 

4.00E+00 3. 54E-06 1.54E-04 7. 98E-02 9.50E-01 

5.00E+00 3. 25E-06 1. 58E-04 3.06E-02 9.81E-01 

6.00E+00 3.04E-06 1.61E-04 1.15E-02 <9.92E-01 

7.00E+00 2. 85E-06 1.64E-04 4.25E-03 9.97E-01 

8.00E+00 2. 67E-06 1.66E-04 1.57E-03 9. 98E-Ol 

9.00E+00 2.50E-06 1. 69E-04 5. 78E-04 9. 99E-Ol 

1.00E+01 2. 34E-06 1.71E-04 2. 13E-04 9. 99E-Ol 

2.00E+01 1. 25E-06 1. 88E-04 O.OOE+OO 9.99E-01 

3.00E+01 7.04E-07 1. 97E-04 O.OOE+OO 9. 99E-01 

4.00E+Ol 4.30E-07 2.02E-04 O.OOE+OO 9.99E-Ol 

5.00E+01 2. 93E-07 2.06E-04 O.OOE+OO 9. 99E-01 

6.00E+01 2. 25E-07 2.08E-04 O.OOE+OO 9.99E-Ol 

7.00E+01 1.90E-07 2. 11E-04 O.OOE+OO 9. 99E-Ol 

8.00E+Ol 1. 73E-07 2. 12E-04 O.OOE+OO 9.99E-Ol 

9.00E+01 1. 64E-07 2. 14E-04 O.OOE+OO 9. 99E-Ol 

1.00E+02 1.60E-07 2. 16E-04 O.OOE+OO 9.99E-01 

2.00E+02 1. 52E-07 2.31E-04 O.OOE+OO 9. 99E-01 

3.00E+02 1.49E-07 2.46E-04 O.OOE+OO 9. 99E-01 

4.00E+02 1. 46E-07 2.61E-04 O.OOE+OO 9. 99E-01 

5.00E+02 1.43E-07 2. 75E-04 O.OOE+OO 9. 99E-Ol 

7.00E+02 1.38E-07 3.04E-04 O.OOE+OO 9. 99E-Ol 

8.00E+02 1. 35E-07 3. 17E-04 O.OOE+OO 9.99E-01 

9.00E+02 1. 33E-07 3. 31E-04 O.OOE+OO 9. 99E-Ol 

1.00E+03 1.30E-07 3. 44E-04 O.OOE+OO 9. 99E-01 

2.00E+03 1.07E-07 4. 62E-04 O.OOE+OO 9.99E-Ol 

3.00E+03 8. 75E-08 5. 58'E-04 O.OOE+OO 9.99E-Ol 

4.00E+03 7. 18E-08 6. 38E-04 O.OOE+OO 9.99E-Ol 

5.00E+03 5. 89E-08 7.03E-04 O.OOE+OO 9.99E-01 

7.00E+03 3. 96E-08 8.00E-04 O.OOE+OO 9. 99E-01 

8.00E+03 3. 25E-08 8. 36E-04 O.OOE+OO 9.99E-Ol 

9.00E+03 2. 67E-08 8. 65E-04 O.OOE+OO 9. 99E-01 

1.00E+'04 2. 19E-08 8.90E-04 O.OOE+OO 9. 99E-Ol 

8-619 
INGESTION f l- I.OOE-03 BALFLIFE= 4.87E+03 DAYS EUROPIUM 152 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 2. 94E-04 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 5. 82E-04 9.93E-Ol 9. 94E-Ol 

3.00E-Ol 7.41E-04 9.80E-Ol 9.81E-Ol 

4.00E-Ol 8. 21E-04 9.57E-Ol 9. 58E-Ol 

5.00E-Ol 8.58E-04 9.27E-Ol 9. 28E-Ol 

6.00E-Ol 8.73E-04 8. 91E-Ol 8.92E-Ol 

7.00E-Ol 8.78E-04 8.50E-Ol 8.50E-Ol 

8.00E-Ol 8.77E-04 8.05E-Ol 8.06E-Ol 

9.00E-Ol 8. 75E-04 7. 59E-Ol 7.60E-Ol 

1.00E+00 8.71E-04 7. 13E-Ol 7. 13E-Ol 

2.00E+00 8. 54E-04 3. 23E-Ol 3. 24E-Ol 

3.00E+00 8. 49E-04 1. 29E-Ol 1.29E-Ol 

4.00E+00 8.45E-04 4. 88E-02 4. 96E-02 

5.00E+00 8.42E-04 1.82E-02 1.90E-02 

6.00E+00 8.39E-04 6. 73E-03 7. 57E-03 

7.00E+00 8. 36E-04 2. 48E-03 3. 32E-03 

8.00E+00 . 8.33E-04 9. 14E-04 1. 75E-03 

9.00E+00 8.30E-04 3. 36E-04 1. 17E-03 

1.00E+Ol 8. 28E-04 1. 24E-04 9. 51E-04 

2.00E+Ol 8.10E-04 O.OOE+OO 8.1OE-04 

3.00E+Ol 7. 99E-04 O.OOE+OO 7. 99E-04 

4.00E+Ol 7.93E-04 0.00£+00 7. 93E-04 

5.00E+Ol 7. 88E-04 O.OOE+OO 7. 88E-04 

6.00E+Ol 7.85E-04 O.OOE+OO 7. 85E-04 

7.00E+Ol 7. 82E-04 O.OOE+OO 7.82E-04 

8.00E+Ol 7. 79E-04 O.OOE+OO 7. 79E-04 

9.00E+Ol 7. 76E-04 O.OOE+OO 7. 76E-04 

1.00E+02 7. 73E-:-04 O.OOE+OO 7. 73E-04 

2.00E+02 7. 47E-04 O.OOE+OO 7.47E-04 

3.00E+02 7. 22E-04 O.OOE+OO 7. 22E-04 

4.00E+02 6.98E-04 O.OOE+OO 6. 98E-04 

5.00E+02 6. 75E-04 O.OOE+OO 6. 75E-04 

6.00E+02 6.52E-04 O.OOE+OO 6. 52E-04 

7.00E+02 6.30E-04 O.OOE+OO 6.30E-04 

8.00E+02 6.09E-04 O.OOE+OO 6.09E-04 

9.00E+02 5.89E-04 O.OOE+OO 5. 89E-04 

1.00E+03 5. 69E-04 O.OOE+OO 5. 69E-04 

2.00E+03 4.05E-04 O.OOE+OO 4.05E-04 

3.00E+03 2. 88E-04 O.OOE+OO 2. 88E-04 

4.00E+03 2.05E-04 O.OOE+OO 2.05E-04 

5.00E+03 1.46E-04 O.OOE+OO . 1. 46E-04 

7.00E+03 7. 38E-05 O.OOE+OO 7. 38E-05 

8.00E+03 5. 25E-05 O.OOE+OO 5. 25E-OS 

9.00E+03 3.74E-05 O.OOE+OO 3. 74E-05 

1.00E+04 2. 66E-05 O.OOE+OO 2. 66E-05 

2.00E+04 8. 83E-07 O.OOE+OO S.83E-07 

B-620 
INGESTION £1= l.ooE-03 BALFLIFE- 4.87E+03 DAYS EUROPIUM 152 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 4.50E-06 6.1OE-04 

2.00E-Ol 1. 95E-05 5.90E-03 

3.00E-Ol 3.90E-05 1. 93E-02 

4.00E-Ol 5. 84E-05 4. 16E-02 

5.00E-Ol 7.57E-05 7. 17E-02 

6.00E-Ol 9.03E-05 1.08E-Ol 

7.00E-Ol 1.02E-04 1.49E-01 

8.00E-Ol 1. 12E-04 1. 94E-01 

9.00E-01 1. 19E-04 2.40E-Ol 

1.00E+00 1. 25E-04 1. 25E-04 2. 86E-Ol 2. 86E-Ol 

2.00E+00 2.08E-05 1. 46E-04 3. 89E-Ol 6. 76E-01 

3.00E+00 4. 78E-06 1. 51E-04 1. 95E-01 8.70E-Ol 

4.00E+00 3. 53E-06 1. 54E-04 7.97E-02 9.50E-Ol 

5.00E+00 3. 25E-06 1. 58E-04 3.06E-02 9.80E-Ol 

6.00E+00 3.04E-06 1.61E-04 1. 15E-02 9.91E-Ol 

7.00E+00 2. 84E-06 1. 63E-04 4. 25E-03 9. 96E-Ol 

8.00E+00 2. 66E-06 1. 66E-04 1. 57E-03 9. 97E-Ol 

9.00E+00 2.50E-06 1. 69E-04 5.77E-04 9. 97E-Ol 

1.00E+Ol 2. 34E-06 1.71E-04 2. 12E-04 9. 97E-Ol 

2.00E+Ol 1. 25E-06 1.87E-04 O.OOE+OO 9. 96E-Ol 

3.00E+Ol 7.01E-07 1.96E-04 O.OOE+OO 9.95E-Ol 

4.00E+Ol 4. 28E-07 2.01E-04 O.OOE+OO 9. 93E-Ol 

5.00E+Ol 2.91E-07 2.04E-04 O.OOE+OO 9. 92E-Ol 

6.00E+01 2. 23E-07 2.07E-04 O.OOE+OO 9.90E-Ol 

7.00E+Ol 1. 89E-07 2.08E-04 O.OOE+OO 9. 89E-Ol 

8.00E+Ol 1.71E-07 2.1OE-04 O.OOE+OO 9.88E-Ol 

9.00E+01 1. 62E-07 2. 11E-04 O.OOE+OO 9. 86E-Ol 

1.00E+02 1. 57E-07 2. 13E-04 O.OOE+OO 9. 85E-Ol 

2.00E+02 1. 48E-07 2. 25E-04 O.OOE+OO 9. 71E-01 

3.00E+02 1. 43E-07 2. 36E-04 O.OOE+OO 9. 57E-Ol 

4.00E+02 1. 38E-07 2. 46E-04 O.OOE+OO 9. 44E-Ol 

5.00E+02 1. 34E-07 2. 56E-04 O.OOE+OO 9.30E-Ol 

6.00E+02 1. 29E-07 2. 66E-04 O.OOE+OO 9. 17E-Ol 

7.00E+02 1. 25E-07 2. 75E-04 O.OOE+OO 9.04E-Ol , . 8.00E+02 1.21E-07 2.83E-04 O.OOE+OO 8.91E-Ol 

9.00E+02 1. 17E-07 2. 91E-04 O.OOE+OO 8. 79E-Ol 

1.00E+03 1. 13E-07 2.98E-04 O.OOE+OO 8.66E-Ol· 

2.00E+03 8.02E-08 3. 47E-04 O.OOE+OO 7.51E-Ol 

3.00E+03 5.70E-08 3.64E-04 O.OOE+OO 6. 52E-Ol 

4.00E+03 4.06E-08 3. 61E-04 O.OOE+OO 5. 65E-Ol 

5.00E+03 2. 89E-08 3. 45E-04 O.OOE+OO 4.90E-Ol 

6.00E+03 2.05E-08 3. 22E-04 O.OOE+OO 4. 25E-Ol 

7.00E+03 1. 46E-08 2.95E-04 O.OOE+OO 3. 69E-Ol 

8.00E+03 1.04E-08 2. 67E-04 O.OOE+OO 3.20E-Ol 

B-621 
INGESTION fl''''' 1.00E-03 IlALFLIFE= 3.21£+03 DAYS EUROPIUM 154 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 2. 94E-04 9.99E-01 9. 99E-01 

2.00E-01 5. 82E-04 9.93E-01 9. 94E-01 

3.00E-01 7.41E-04 9.80E-01 9.81E-01 

4.00E-01 8. 21E-04 9.57E-01 9. 58E-01 

5.00E-01 8. 58E-04 9.27E-01 9. 28E-01 

6.00E-01 8. 73E-04 8.91E-01 8.92E-01 

7.00E-01 8.78E-04 8.50E-01 8.50E-01 

8.00E-01 8. 77E-04 8.05E-01 8.06E-01 

9.00E-01 8. 74E-04 7. 59E-01 7.60E-01 

1.00E+00 8.71E-04 7. 13E-01 7. 13E-01 

2.00E+00 8.53E-04 3. 23E-01 3. 24E-01 

3.00E+00 8.49E-04 1.29E-01 1. 29E-01 

4.00E+00 8. 45E-04 4. 88E-02 4. 96E-02 

5.00E+00 8.41E-04 1.82E-02 1.90E-02 

6.00E+00 8. 38E-04 6.73E-03 7. 56E-03 

7.00E+00' 8. 35E-04 2. 48E-03 3. 32E-03 

8.00E+00 8. 32E-04 9. 13E-04 1. 75E-03 

9.00E+00 8.30E-04 3. 36E-04 1. 17E-03 

1.00E+01 8.27E-04 1. 24E-04 9.51E-04 

2.00E+01 8.09E-04 O.OOE+OO 8.09E-04 

3.00E+01 7. 98E-04 O.OOE+OO 7. 98E-04 

4.00E+01 7.9lE-04 O.OOE+OO 7.91 

5.00E+01 7. 86E-04 O.OOE+OO 7. 86E-04 

6.00E+01 7. 81E-04 O.OOE+OO 7.81E-04 

7.00E+01 7. 78E-04 O.OOE+OO 7. 78E-04 

8.00E+Ol 7. 74E-04 O.OOE+OO 7'. 74E-04 

9.00E+01 7. 71E-04 O.OOE+OO 7. 71E-04 

1.00E+02 7. 68E-04 O.OOE+OO 7. 68E-04 

2.00E+02 7. 36E-04 O.OOE+OO 7. 36E-04 

3.00E+02 7.07E-04 O.OOE+OO 7.07E-04 

4.00E+02 6. 78E-:,04 O.OOE+OO 6. 78E-04 

5.00E+02 6. 51E-04 O.OOE+OO 6. 51E-04 

6.00E+02 6. 24E-04 O.OOE+OO 6. 24E-04 

7.00E+02 5. 99E-04 O.OOE+OO 5. 99E-04 

8.00E+02 5. 75E-04 O.OOE+OO 5. 75E-04 

9.00E+02 5. 51E-04 O.OOE+OO 5. 51E-04 

1.00E+03 S.29E-04 O.OOE+OO 5. 29E-04 

2.00E+03 3.50E-04 O.OOE+OO 3.50E-04 

3.00E+03 2. 31E-04 O.OOE+OO 2.31E-04 

4.00E+03 1. 53E-04 O.OOE+OO 1. 53E-04 

5.00E+03 1.01E-04 O.OOE+OO 1.0lE-04 

7.00E+03 4. 42E-05 O.OOE+OO 4. 42E-05 

8.00E+03 2. 92E-05 O.OOE+OO 2. 92E-05 

9.00E+03 1. 93E-05 O.OOE+OO 1. 93E-05 

1.00E+04 1. 28E-OS O.OOE+OO 1.28E-OS 

2.00E+04 2.04E-07 O.OOE+OO 2.04E-07 

B-622 
INGESTION £1= 1.00£-03 UALFLIFE- 3.21£+03 DAYS £U&OPIUK 154 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 4.50E-06 6.10E-04 

2.00E-Ol 1. 95E-05 5.90E-03 

3.00E-Ol 3.90E-05 1.93E-02 

4.00E-Ol 5. 84E-05 4. 16E-02 

5.00E-Ol 7. 57E-05 7. 17E-02 

6.00E-Ol 9.03E-05 1.08E-Ol 

7.00E-Ol 1.02E-04 1.49E-Ol 

8.00E-Ol 1. 12E-04 1. 94E-Ol 

9.00E-Ol 1. 19E-04 2.40E-Ol 

1.00E+00 1. 25E-04 1.25E-04 2.86E-Ol 2. 86E-Ol 

2.00E+00 2.08E-05 1.46E-04 3. 89E-Ol 6. 75E-Ol 

3.00E+00 4. 78E-06 1. 51E-04 1. 95E-Ol 8.70E-Ol 

4.00E+00 3. 53E-06 1.54E-04 7.97E-02 9.49E-Ol 

5.00E+00 3. 25E-06 1. 58E-04 3.06E-02 9.80E-Ol 

6.00E+00 3.04E-06 1.61E-04 1.15E-02 9.91E-Ol 

7.00E+00 2.84E-06 1. 63E-04 4. 25E-03 9. 95E-Ol 

8.00E+00 2. 66E-06 1. 66E-04 1.57E-03 9.96E-Ol 

9.00E+00 2. 49E-06 1. 68E-04 5.77E-04 9.97E-Ol 

1.00E+Ol 2. 34E-06 1.71E-04 2.12E-04 9.97E-Ol 

2.00E+Ol 1. 24E-06 1. 87E-04 O.OOE+OO 9. 95E-Ol 

3.00E+Ol 6. 99E-07 1. 96E-04 O.OOE+OO 9. 93E-Ol 

4.00E+Ol 4. 27E-07 2.01E-04 O.OOE+OO 9.90E-Ol 

5.00E+Ol 2.90E-07 2.04E-04 O.OOE+OO 9. 88E-Ol 

6.00E+Ol 2. 22E-07 2.06E-04 O.OOE+OO 9.86E-Ol 

7.00E+Ol 1.88E-07 2.07E-04 O.OOE+OO 9. 84E-Ol 

8.00E+Ol 1.70E-07 2.09E-04 O.OOE+OO 9.82E-Ol 

9.00E+Ol 1.61E-07 2.10E-04 O.OOE+OO 9.80E-Ol 

1.00E+02 1. 56E-07 2.11E-04 O.OOE+OO 9. 78E-Ol 

2.00E+02 1.46E-07 2.21E-04 O.OOE+OO 9.57E-Ol 

3.00E+02 1.40E-07 2.31E-04 O.OOE+OO 9.36E-Ol 

4.00E+02 1.34E-07 2. 39E-04 O.OOE+OO 9. 16E-Ol 

5.00E+02 1.29E-07 2.47E-04 O.OOE+OO 8. 97E-Ol 

6.00E+02 1. 24E-07 2. 54E-04 O.OOE+OO 8. 78E-Ol 

7.00E+02 . 1. 19E-07 2. 61E-04 O.OOE+OO 8. 59E-Ol 

8.00E+02 1. 14E-07 2. 67E-04 O.OOE+OO 8.41E-Ol , ,.;. 9.00E+02 1.09E-07 2.72E-04 O.OOE+OO 8.23E-Ol 

1.00E+03 1.05E-07 2.77E-04 O.OOE+OO 8.05E-Ol 

2.00E+03 6. 92E-08 3.00E-04 O.OOE+OO 6. 49E-Ol 

3.00E+03 4. 58E-08 2.92E-04 O.OOE+OO 5.23E-Ol 

4.00E+03 3.03E-08 2. 69E-04 O.OOE+OO 4.21E-Ol 

5.00E+03 2.00E-08 2.39E-04 O.OOE+OO 3.40E-Ol 

6.00E+03 1.32E-08 2.07E-04 O.OOE+OO 2. 74E-Ol 

B-623 
INGESTION fl= 3.00E-04 STABLE GADOLINIUM 151 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-OI 8.7SE-OS 9. 99E-01 9. 99E-OI 

2.00E-01 1.71E-04 9. 94E-OI 9.94E-OI 

3.00E-Ol 2.16E-04 9.80E-OI 9.8IE-OI 

4.00E-OI 2. 37E-04 9. 58E-Ol 9. 58E-01 

S.OOE-OI 2.4SE-04 9. 28E-01 9. 28E-01 

6.00E-OI 2. 47E-04 8.9IE-Ol 8. 92E-OI 

7.00E-OI 2. 46E-04 B.50E-OI 8.5IE-OI 

8.00E-OI 2. 45E-04 B.06E-OI 8.06E-OI 

9.00E-Ol 2. 43E-04 7.60E-OI 7.60E-Ol 

1.00E+OO 2.4IE-04 7. 13E-OI 7.13E-0l 

2.00E+OO 2. 33E-04 3. 24E-01 3. 24E-OI 

3.00E+OO 2. 32E-04 1.29E-Ol 1.29E-Ol 

4.00E+OO 2. 32E-04 4. 89E-02 4.9IE-02 

5.00E+OO 2.31E-04 1. 82E-02 1.8SE-02 

6.00E+OO 2.3IE-04 6. 74E-03 6. 97E-03 

7.00E+OO 2.30E-04 2. 49E-03 2.nE-03 

8.00E+OO 2.30E-04 9.1SE-04 l.lSE-03 

9.00E+OO 2.30E-04 3. 37E-04 5. 66E-04 

1.00E+OI 2.29E-04 1. 24E-04 3.S3E-04 

2.00E+01 2. 26E-04 O.OOE+OO 2. 26E-04 

3.00E+OI 2.2SE-04 O.OOE+OO 2. 25E-04 

4.00E+01 2. 24E-04 O.OOE+OO 2. 24E-04 

5.00E+OI 2. 23E-04 O.OOE+OO 2. 23E-04 

6.00E+OI 2. 22E-04 O.OOE+OO 2. 22E-04 

7.00E+Ol 2. 22E-04 O.OOE+OO 2. 22E-04 

8.00E+OI 2. 22E-04 O.OOE+OO 2. 22E-04 

9.00E+OI 2.2IE-04 O.OOE+OO 2.2IE-04 

I.OOE+02 2.21E-04 O.OOE+OO 2. 21E-04 

2.00E+02 2.l6E-04 O.OOE+OO 2. 16E-04 

3.00E+02 2.12E-04 O.OOE+OO 2. 12E":'04 

4.00E+02 2.08E-04 O.OOE+OO 2.08E-04 

5.00E+02 2.04E-04 O.OOE+OO 2.04E-04 

6.00E+02 2.00E-04 O.OOE+OO 2.00E-04 

7.00E+02 1. 96E-04 O.OOE+OO 1. 96E-04 

8.00E+02 1. 92E-04 O.OOE+OO 1. 92E-04 

9.00E+02 1.88E-04 O.OOE+OO 1. 88E-04 

1.00E+03 1.8SE-04 O.OOE+OO 1. 85E-04 

2.00E+03 1. SIE-04 O.OOE+OO 1. 51E-04 

3.00E+03 1.24E-04 O.OOE+OO 1. 24E-04 

4.00E+03 1.02E-04 O.OOE+OO 1.02E-04 

S.OOE+03 8. 36E-OS O.OOE+OO 8. 36E-05 

7.00E+03 S.63E-05 O.OOE+OO 5. 63E-05 

8.00E+03 4. 62E-05 O.OOE+OO 4. 62E-OS 

9.00E+03 3. 79E-05 O.OOE+OO 3. 79E-OS 

1.00E+04 3.11E-05 O.OOE+OO 3.11E-OS 

2.00E+04 4. 29E-06 O.OOE+OO 4.29E-06 

B-624 
INGESTION f l- 3.00E-04 STABLE GADOLINIUM 157 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTE~UC NON-SYSTEMIC 

------------------------- ------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 2.10E-06 6.10E-04 

2.00E-01 9.10E-06 5.90E-03 

3.00E-01 1.82E-05 1.94E-02 

4.00E-Ol 2.72E-05 4. 16E-02 

5.00E-01 3. 53E-05 7.18E-02 

6.00E-01 4.20E-05 1.08E-01 

7.00E-Ol 4.75E-05 1.49E-01 

8.00E-01 5. 19E-05 1.94E-01 

9.00E-Ol 5. 53E-05 2.40E-01 

1.00E+00 5.80E-05 5.80E-05 2.86E-01 2.86E-01 

2.00E+00 8. 57E-06 6. 66E-05 3.90E-01 6.76E-01 

3.00E+00 1.09E-06 6.77E-05 1.95E-01 8.71E-01 

4.00E+00 5. 73E-07 6.82E-05 7.98E-02 9.51E-01 

5.00E+00 5.10E-07 6. 88E-05 3.07E-02 9.81E-Ol 

6.00E+00 4.77E-07 6.92E-05 1. 15E-02 9.93E-Ol 

7.00E+00 4.48E-07 6.97E-05 4. 26E-03 9.97E-01 

8.00E+00 4.21E-07 7. OlE-OS 1.57E-03 9.99E-Ol 

9.00E+00 3. 96E-07 7.05E-05 5. 79E-04 9. 99E-01 

1.00E+Ol 3. 7·2£-07 7.09E-05 2. 13E-04 1.00E+00 

2.00E+Ol 2.08E-07 7.36E-05. O.OOE+OO 1.00E+00 

3.00E+01 1.26E-07 7.52E-05 O.OOE+OO 1.00E+00 

4.00E+01 8. 52E-08 7.62E-05 O.OOE+OO 1.00E+00 

5.00E+01 6. 46E-08 7. 69E-05 O.OOE+OO 1.00E+00 

6.00E+Ol 5. 43E-08 7. 75E-05 O.OOE+OO 1.00E+00 

7.00E+01 4.91E-08 7.80E-05 O.OOE+OO 1.00E+00 

8.00E+01 4.64E-08 7.85E-05 O.OOE+OO 1.00E+00 

9.00E+01 4.51E-08 7.89E-05 O.OOE+OO 1.00E+00 

1.00E+02 4.43E-08 7. 94E-05 O.OOE+OO 1.00E+00 

2.00E+02 4. 28E-08 8. 37E-05 O.OOE+OO 1.00E+00 

3.00E+02 4.20E-08 8.80E-05 O.OOE+OO 1.00E+00 

4.00E+02 4. 12E-08 9.21E-05 O.OOE+OO 1.00E+00 

5.00E+02 4.04E-08 9.62E-05 O.OOE+OO 1.00E+00 

6.00E+02 3. 96E-08 1.00E-04 O.OOE+OO 1.00E+00 

7.00E+02 3. 88E-08 1.04E-04 O.OOE+OO 1.00E+00 > ••• ~ .. .. 8.00E+02 3.80E-08 1.08E-04 O.OOE+OO 1.00E+00 .. 

. -..... 9.00E+02 3.73E-08 1. 12E-04 O.OOE+OO 1.00E+00 

1.00E+03 3.66E-08 1. 15E-04 O.OOE+OO 1.00E+00 

2.00E+03 3.00E-08 1. 49E-04 O.OOE+OO 1.00E+00 

3.00E+03 2.46E-08 1.76E-04 O.OOE+OO 1.00E+00 

4.00E+03 2.02E-08 1. 98E-04 O.OOE+OO 1.00E+00 

5.00E+03 1.66E-08 2. 16E-04 O.OOE+OO 1.00E+00 

6.00E+03 1. 36E-08 2.31E-04 O.OOE+OO 1.00E+00 

7.00E+03 1. 11E-08 2.44E-04 O.OOE+OO 1.00E+00 

B-625 
INGESTION £1= 3.00E-04 STABLE TERBIUM 159 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 8.77E-05 9.99E-01 9. 99E-01 

2.00E-01 1.72E-04 9.94E-01 9. 94E-01 

3.00E-01 2. 17E-04 9.80E-01 9.81E-01 

4.00E-01 2.39E-04 9. 58E-01 9.58E-01 

5.00E-01 2.48E-04 9. 28E-01 9. 28E-01 

6.00E-01 2.51E-04 8.91E-01 8.92E-01 

7.00E-01 2. 51E-04 8.50E-01 8.51E-Ol 

8.00E-01 2. 49E-04 8.06E-01 8.06E-01 

9.00E-01 2. 48E-04 7.60E-01 7.60E-01 

1.00E+00 2. 46E-04 7. 13E-Ol 7. 13E-01 

2.00E+00 2. 39E-04 3.24E-01 3. 24E-01 

3.00E+00 2. 37E-04 1.29E-01 1. 29E-Ol 

4.00E+00 2.36E-04 4.89E-02 4. 91E-02 

5.00E+00 2. 36E-04 1.82E-02 1.85E-02 

6.00E+00 2. 35E-04 6. 74E-03 6. 98E-03 

7.00E+00 2. 34E-04 2. 49E-03 2. 72E-03 

8.00E+00 2. 33E-04 9. 15E-04 1. 15E-03 

9.00E+00 2. 33E-04 3.37£-04 5.70E-04 

1.00E+01 2.32E-04 1.24E-04 3.56E-04 

2.00E+01 2. 28E-04 O.OOE+OO 2.28E-04 

3.00E+01 2. 26E-04 O.OOE+OO 2. 26E-04 

4.00E+Ol 2. 24E-04 O.OOE+OO 2. 24E-04 

5.00E+01 2.23E-04 O.OOE+OO 2.23E-04 

6.00E+Ol 2.23£-04 O.OOE+OO 2. 23E-04 

7.00E+Ol 2.22E-04 O.OOE+OO 2. 22E-04 

8.00E+01 2. 22E-04 O.OOE+OO 2. 22E-04 

9.00E+01 2.21E-04 O.OOE+OO 2.21E-04 

1.00E+02 2. 21E-04 O.OOE+OO 2.21E-04 

2.00E+02 2. 16E-04 O.OOE+OO 2.16E-04 

3.00E+02 2. 12E-04 O.OOE+OO 2. 12E-04 

4.00E+02 2.08E-04 O.OOE+OO 2.08E-04 

5.00E+02 2.04E-04 O.OOE+OO 2.04E-04 

6.00E+02 2.00E-04 O.OOE+OO 2.00E-04 

7.00E+02 1.96E-04 O.OOE+OO 1.96E-04 

8.00E+02 1.92E-04 O.OOE+OO 1.92E-04 

9.00E+02 1. 88E-04 O.OOE+OO 1. 88E-04 

1.00E+03 1. 85E-04 O.OOE+OO 1.85E-04 

2.00E+03 1. 51E-04 O.OOE+OO 1. 51E-04 

3.00E+03 1. 24E-04 O.OOE+OO 1.24E-04 

4.00E+03 1.02E-04 O.OOE+OO 1.02E-04 

5.00E+03 8. 36E-05 O.OOE+OO 8.36E-05 

7.00E+03 5. 63E-05 O.OOE+OO 5.63E-05 

8.00E+03 4. 62E-05 O.OOE+OO 4. 62E-05 

9.00E+03 3. 79E-05 O.OOE+OO 3. 79E-05 

1.00E+04 3. 11E-05 O.OOE+OO 3. 11E-05 

2.00E+04 4. 29E-06 O.OOE+OO 4. 29E-06 

B-626 
INGESTIOB f 1- 3.00E-04 STABLE TERBIUM 159 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.92E-06 6.lOE-04 

2.00E-01 S.30E-06 5.90E-03 

3.00E-01 1.66E-05 1. 94E-02 

4.00E-01 2.4SE-05 4. 16E-02 

S.OOE-Ol 3. 22E-05 7.18E-02 

6.00E-01 3.84E-05 1.08E-01 

7.00E-01 4. 34E-05 1.49E-01 

S.00E-01 4. 75E-05 1.94E-01 

9.00E-01 5.06E-05 2.40E-01 

1.00E+00 5. 31E-05 S.31E-05 2.S6E-01 2.S6E-Ol 

2.00E+00 8. 22E-06 6.13E-OS 3.90E-01 6. 76E-01 

3.00E+00 1.39E-06 6. 27E-05 1.9SE-01 8.71E-01 

4.00E+00 9.01E-07 6. 36E-OS 7.9SE-02 9.S1E-01 

S.OOE+OO 8. 19E-07 6.4SE-05 3.07E-02 9.S1E-Ol 

6.00E+00 7.6SE-07 6.S2E-OS 1.1SE-02 9. 93E-Ol 

7.00E+00 7.17E-07 6. 59E-05 4.26E-03 9. 97E-01 

S.OOE+OO 6. 72E-07 6. 66E-OS 1.S7E-03 9.99E-01 

9.00E+00 6.30E-07 6. 72E-05 S.79E-04 9. 99E-01 

1.00E+01 S.91E-07 6.7SE-OS 2. 13E-04 1.00E+00 

2.00E+01 3. 17E-07 7.21E-05 O.OOE+OO 1.00E+00 

3.00E+01 1.S1E-07 7. 44E-OS O.OOE+OO 1.00E+00 

4.00E+01 1. 13E-07 7.5SE-05 O.OOE+OO 1.00E+00 

S.OOE+Ol 7.S3E-OS 7. 67E-05 O.OOE+OO 1.00E+00 

6.00E+Ol 6.l1E-OS 7.74E-OS O.OOE+OO 1.00E+00 

7.00E+01 S.2SE-OS 7.S0E-OS O.OOE+OO 1.00E+00 

S.OOE+Ol 4.S1E-OS 7.SSE-05 O.OOE+OO 1.00E+00 

9.00E+01 4.S9E-OS 7.S9E-OS O.OOE+OO 1.00E+00 

1.00E+02 4.4SE-OS 7. 94E-05 O.OOE+OO 1.00E+00 

2.00E+02 4.2SE-OS 8. 37E-05 O.OOE+OO 1.00E+00 

3.00E+02 4.20E-OS S.80E-OS O.OOE+OO 1.00E+00 

4.00E+02 4. 12E-08 9.21E-OS O.OOE+OO 1.00E+00 

S.00E+02 4.04E-08 9. 62E-05 O.OOE+OO 1.00E+00 

6.00E+02 3. 96E-08 1.00E-04 O.OOE+OO 1.00E+00 

7.00E+02 3. SSE-OS 1.04E-04 O.OOE+OO 1.00E+00 

S.00E+02 3.S0E-OS 1.0SE-04 O.OOE+OO 1.00E+00 . ,,', ," 

9.00E+02 3. 73E-OS 1. 12E-04 O.OOE+OO 1.00E+00 

1.00E+03 3. 66E-OS 1.1SE-04 O.OOE+OO 1.00E+00 

2.00E+03 3.00E-OS 1. 49E-04 O.OOE+OO 1.00E+00 

3.00E+03 2. 46E-OS 1. 76E-04 O.OOE+OO 1.00E+00 

4.00E+03 2.02E-OS 1.9SE-04" O.OOE+OO 1.00E+00 

S.00E+03 1. 66E-OS 2. 16E-04 O.OOE+OO 1.00E+00 

6.00E+03 1. 36E-08 2.31E-04 O.OOE+OO 1.00E+00 

7.00E+03 1.11E-08 2. 44E-04 O.OOE+OO 1.00E+00 

B-627 
INGESTION f1= 3.00E-04 STABLE DYSPIIOSIUM 162 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 8. 69E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 69E-04 9. 94E-Ol 9. 94E-Ol 

3.00E~01 2. l1E-04 9.80E-Ol 9.81E-Ol 

4.00E-Ol 2. 29E-04 9. 58E-Ol 9. 58E-Ol 

5.00E-Ol 2.35E-04 9. 28E-Ol 9. 28E-Ol 

6.00E-Ol 2. 36E-04 8.91E-Ol 8.92E-Ol 

7.00E-Ol 2. 34E-04 8.50E-Ol 8. 51E-Ol 

8.00E-Ol 2.31E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 2. 28E-04 7.60E-Ol 7.60E-Ol 

1.00E+00 2. 25E-04 7. 13E-Ol 7. 13E-Ol 

2.00E+00 2. 16E-04 3.24E-Ol 3.24E-Ol 

3.00E+00 2. 15E-04 1.29E-Ol 1. 29E-Ol 

4.00E+00 2. 14E-04 4. 89E-02 4.91E-02 

5.00E+00 2. 14E-04 1. 82E-02 1. 84E-02 

6.00E+00 2. 14E-04 6. 74E-03 6. 95E-03 

7.00E+00 2. 13E-04 2. 49E-03 2.70E-03 

8.00E+00 2. 13E-04 9. 15E-04 1. 13E-03 

9.00E+00 2. 13E-04 3. 37E-04 5.50E-04 

1.00E+01 2. 13E-04 1. 24E-04 3.37E-04 

2.00E+Ol 2.11E-04 O.OOE+OO 2. llE-04 

3.00E+Ol 2.10E-04 O.OOE+OO 2.10E-04 

4.00E+Ol 2.09E-04 O.OOE+OO 2.09E-0 

5.00E+Ol 2.08E-04 O.OOE+OO 2.08E 

6.00E+Ol 2.08E-04 O.OOE+OO 2.08E-04 

7.00E+Ol 2.07E-04 O.OOE+OO 2.07E-04 

8.00E+Ol 2.07E-04 O.OOE+OO 2.07E-04 

9.00E+Ol 2.06E-04 O.OOE+QO 2.06E-04 

1.00E+02 2.06E-04 O.OOE+OO 2.06E-04 

2.00E+02 2.02E-04 O.OOE+OO 2.02E-04 

3.00E+02 1.98E-04 O.OOE+OO 1. 98E-04 

4.00E+02 1. 94E-04 O.OOE+OO 1.94E-04 

5.00E+02 1.90E-04 O.OOE+OO 1.90E-04 

6.00E+02 1. 86E-04 O.OOE+OO 1.86E-04 

7.00E+02 1.83E-04 O.OOE+OO 1.83E-04 

8.00E+02 1.79E-04 O.OOE+OO 1. 79E-04 

9.00E+02 1.76E-04 O.OOE+OO 1. 76E-04 

1.00E+03 1.72E-04 O.OOE+OO 1.72E-04 

2.00E+03 1.41E-04 O.OOE+OO 1.41E-04 

3.00E+03 1.16E-04 O.OOE+OO 1.16E-04 

4.00E+03 9.51E-05 O.OOE+OO 9.51E-05 

5.00E+03 7.80E-05 O.OOE+OO 7.80E-05 

7.00E+03 5.25E-05 O.OOE+OO 5.25E-05 

8.00E+03 4.31E-05 O.OOE+OO 4.3lE-05 

9.00E+03 3.53E-05 O.OOE+OO 3. 53E-05 

1.00E+04 2.90E-05 O.OOE+OO 2.90E-05 

2.00E+04 4.00E-06 O.OOE+OO 4.00E-06 

B-628 
INGESTION fl= 3.00E-04 STABLE DYSPROSIUM 162 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 2.67E-06 6.10E-04 

2.00E-Ol 1. 16E-OS S.90E-03 

3.00E-Ol 2. 31E-OS 1. 94E-02 

4.00E-Ol 3.46E-OS 4. 16E-02 

S.OOE-01 4.4BE-OS 7.1BE-02 

6.00E-Ol S.33E-OS 1.0BE-01 

7.00E-01 6.03E-OS 1.49E-01 

8.00E-01 6.SBE-OS 1. 94E-Ol 

9.00E-Ol 7.02E-OS 2.40E-OI 

1.OOE+OO 7.3SE-OS 7.3SE-OS 2.B6E-Ol 2.B6E-Ol 

2.00E+OO 1.OSE-OS B.41E-OS 3.90E-Ol 6. 76E-Ol 

3.00E+OO 1.04E-06 8.SIE-OS 1.9SE-OI 8.7IE-OI 

4.00E+OO 4. 13E-07 B.SSE-OS 7.9BE-02 9.S1E-Ol 

S.OOE+OO 3.S3E-07 8.S9E-OS 3.07E-02 9.BIE-Ol 

6.00E+OO 3.30E-07 B.62E-OS 1.1SE-02 9. 93E-Ol 

7.00E+OO 3.10E-07 8.6SE-OS 4. 26E-03 9.97E-Ol 

8.00E+OO 2. 92E-07 B.68E-OS 1.S7E-03 9. 99E-Ol 

9.00E+OO 2. 76E-07 8.71E-OS S.79E-04 9.99E-Ol l~OOE+Ol 2.60E-07 B.74E-OS 2.13E-04 1.00E+OO 

2.00E+OI I.SlE-07 B.93E-OS O.OOE+OO 1.00E+OO 

3.00E+Ol 9.60E-OB 9.0SE-OS O.OOE+OO 1.00E+OO 

4.00E+OI 6. 86E-OB 9.13E-OS O.OOE+OO 1.00E+OO 

S.OOE+Ol S.4BE-OB 9.I9E-OS O.OOE+OO 1.00E+OO 

6.00E+Ol 4. 79E-08 9. 24E-OS O.OOE+OO 1.00E+OO 

7.00E+Ol 4. 44E-OB 9.2BE-OS O.OOE+OO 1.00E+OO 

B.OOE+Ol 4. 26E-08 9. 33E-OS O.OOE+OO 1.00E+OO , 9.00E+Ol 4. 17E-OB 9. 37E-OS O.OOE+OO 1.00E+OO 

1.00E+02 4.12E-08 9.41E-OS O.OOE+OO I.OOE+OO 

2.00E+02 4.00E-OB 9. BIE-OS O.OOE+OO 1.00E+OO 

3.00E+02 3. 92E-OB 1.02E-04 O.OOE+OO 1.00E+OO 

4.00E+02 3. 84E-OB 1.06E-04 O.OOE+OO 1.00E+OO 

S.OOE+02 3.77E-OB 1.10E-04 O.OOE+OO I.OOE+OO 

6.00E+02 3. 69E-OB 1. 14E-04 O.OOE+OO 1.OOE+OO 

7.00E+02 3. 62E-OB 1. 17E-04 O.OOE+OO 1.00E+OO 

~ ~.-'-: ~, : - B.OOE+02 3.SSE-OB 1.2IE-04 O.OOE+OO 1.OOE+OO 

9.00E+02 3.4BE-08 I. 24E-04 O.OOE+OO 1.OOE+OO 

1.OOE+03 3. 41E-OB 1. 28E-04 O.OOE+OO 1.OOE+OO 

2.00E+03 2.80E-08 1.S9E-04 O.OOE+OO I.OOE+OO 

3.00E+03 2.30E-OB 1.B4E-04 O.OOE+OO 1.00E+OO 

4.00E+03 1.8BE-OB 2.0SE-04 O.OOE+OO 1.00E+OO 

S.OOE+03 1.SSE-OB 2. 22E-04 O.OOE+OO 1.00E+OO 

6.00E+03 1. 27E-OB 2. 36E-04 O.OOE+OO 1.00E+OO 

7.00E+03 1.04E-OB 2. 47E-04 O.OOE+OO 1.00E+OO 

, B-629 
INGESTION f1= 3.00E-04 STABLE HOLMIUM 165 

TIME AFTER . FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY· 

1.00E-01 8.8IE-05 9. 99E-OI 9. 99E-OI 

2.00E-OI I. 74E-04 9. 94E-OI 9. 94E-OI 

3.00E-OI 2. 22E-04 9.80E-OI 9.8IE-01 

4.00E-OI 2. 45E-04 9.S8E-OI 9. 58E-OI 

5.00E-Ol 2.56E-04 9. 28E-OI 9. 28E-OI 

6.00E-OI 2.6IE-04 8.9IE-01 8. 92E-OI 

7.00E-OI 2. 62E-04 8.50E-OI 8.51E-OI 

8.00E-OI 2. 62E-04 8.06E-Ol 8.06E-OI 

9.00E-Ol 2.61E-04 7.60E-Ol 7.60E-OI 

1.00E+00 2.60E-04 7.13E-OI 7.13E-Ol 

2.00E+00 2. 55E-04 3. 24E-Ol 3.24E-Ol 

3.00E+00 2. 55E-04 1. 29E-Ol 1.29E-Ol 

4.00E+00 2. 55E-04 4. 89E-02 4.91E-02 

5.00E+00 2. 55E-04 1.82E-02 1.85E-02 

6.00E+00 2. 55E-04 6. 74E-03 7.00E-03 

7.00E+00 2. 55E-04 2. 49E-03 2. 74E-03 

B.OOE+OO 2. 55E-04 9. 15E-04 1.17E-03 

9.00E+OO 2. 55E-04 3. 37E-04 5.91E-04 

1.00E+Ol 2.55E-04 1. 24E-04 3. 78E-04 

2.00E+Ol 2. 54E-04 O.OOE+OO 2. 54E-04 

3.00E+Ol 2. 54E-04 O.OOE+OO 2. 54E-O" 

4.00E+OI 2. 53E-04 O.OOE+OO 2.53 

5.00E+Ol 2. 52E-04 O.OOE+OO 2.5 

6.00E+Ol 2. 52E-04 O.OOE+OO 2. 52E-04 

7.00E+Ol 2.52E-04 O.OOE+OO 2. 52E-04 

8.00E+Ol 2.51E-04 O.OOE+OO 2. 51E-04 

9.00E+Ol 2.51E-04 O.OOE+OO 2. 51E-04 

1.OOE+02 2.50E-04 O.OOE+OO 2.50E-04 

2.00E+02 2. 45E-04 O.OOE+OO 2. 45E-04 

3.00E+02 2.40E-04 O.OOE+OO 2.40E-04 

4.00E+02 2. 36E-04 O.OOE+OO 2. 36E-04 

5.00E+02 2.31E-04 O.OOE+OO 2.31E-04 

6.00E+02 2. 26E-04 O.OOE+OO 2. 26E-04 

7.00E+02 2. 22E-04 O.OOE+OO 2. 22E-04 

8.00E+02 2.1BE-04 O.OOE+OO 2. 18E-04 

9.00E+02 2. 13E-04 O.OOE+OO 2. 13E-04 

1.00E+03 2.09E-04 O.OOE+OO 2.09E-04 

2.00E+03 1.72E-04 O.OOE+OO 1.72E-04 

3.00E+03 1. 41E-04 O.OOE+OO 1.41E-04 

4.00E+03 1. 16E-04 O.OOE+OO 1. 16E-04 

S.OOE+03 9. 48E-OS O.OOE+OO 9.48E-OS 

7.00E+03 6. 38E-OS O.OOE+OO 6. 38E-05 

8.00E+03 S.23E-05 O.OOE+OO 5. 23E-OS 

9.00E+03 4. 29E-05 O.OOE+OO 4. 29E-OS 

1.OOE+04 3.S2E-OS O.OOE+OO 3. 52E-OS 

2.00E+04 4. 86E-06 O.OOE+OO 4.86E-06 

B-630 
INGESTION f l- 3.00E-04 STABLE HOLMIUM 165 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 1.43E-06 6.10E-04 

2.00E-01 6. 18E-06 5.90E-03 

3.00E-01 1. 23E-05 1.94E-02 

4.00E-01 1.85E-05 4. 16E-02 

5.00E-01 2. 39E-05 7. 18E-02 

6.00E-01 2. 85E-05 1.08E-01 

7.00E-01 3. 22E-05 1.49E-01 

8.00E-01 3. 52E-05 1. 94E-01 

9.00E-01 3. 75E-05 2.40E-01 

1.00E+00 3. 92E-05 3. 92E-05 2.86E-01 2.86E-01 

2.00E+00 5. 47E-06 4.47E-05 3.90E-01 6. 76E-01 

3.00E+00 3. 98E-07 4.51E-05 1. 95E-01 8.71E-01 

4.00E+00 7.22E-08 4. 52E-05 7. 98E-02 9.51£-01 

5.00E+00 5. 18E-08 4. 52E-05 3.07E-02 9.81E-01 

6.00E+00 5.05E-08 4. 53E-05 1. 15E-02 9. 93E-01 

7.00E+00 5.04E-08 4.53E-05 4. 26E-03 9. 97E-01 

8.00E+00 5.04E-08 4. 54E-05 1. 57E-03 9.99E-01 

9.00E+00 5.04E-08 4. 54E-05 5. 79E-04 9.99E-01 

1.00E+01 5.04E-08 4. SSE-OS 2. 13E-04 1.00E+00 

2.00E+01 5.03E-08 4.60E-05 O.OOE+OO 1.00E+00 

3.00E+01 5.02E-08 4. 65E-05 O.OOE+OO 1.00E+00 

4.00E+Ol 5.01E-08 4.70E-05 O.OOE+OO 1.00E+00 

5.00E+01 5.00E-08 4. 75E-05 O.OOE+OO 1.00E+00 

6.00E+01 4 .. 99E-08 4.80E-05 O.OOE+OO 1.00E+00 

7.00E+01 4. 98E-08 4. 85E-05 O.OOE+OO 1.00E+00 

8.00E+01 4. 97E-08 4.90E-05 O.OOE+OO 1.00E+00 

9.00E+01 4. 96E-08 4.95E-05 O.OOE+OO 1.00E+00 

1.00E+02 4. 95E-08 5.00E-05 O.OOE+OO 1.00E+00 

2.00E+02 4. 85E-08 5. 49E-05 O.OOE+OO 1.00E+00 

3.00E+02 4. 76E-08 5. 97E-05 O.OOE+OO 1.00E+00 

4.00E+02 4.67E-08 6.44E-05 O.OOE+OO 1.00E+00 

5.00E+02 4. 57E-08 6.90E-05 O.OOE+OO 1.00E+00 

6.00E+02 4. 48E-08 7. 36E-05 O.OOE+oo 1.00E+00 

7.00E+02 4.40E-08 7.80E-05 O.OOE+OO 1.00E+00 

8.00E+02 4.31E-08 8.23E-05 O.OOE+OO 1.00E+00 

9.00E+02 4. 23E-08 8. 66E-05 O.OOE+OO 1.00E+00 

1.00E+03 4. 14E-08 9.08E-05 O.OOE+OO 1.00E+00 

2.00E+03 3.40E-08 1. 28E-04 O.OOE+OO 1.00E+00 

3.00E+03 2. 79E-08 1.59E-04 O.OOE+OO 1.00E+00 

4.00E+03 2. 29E-08 1.84E-04 O.OOE+OO 1.00E+00 

5.00E+03 1.88E-08 2.05E-04 O.OOE+OO 1.00E+00 

6.00E+03 1. 54E-08 2. 22E-04 O.OOE+OO 1.00E+00 

7.00E+03 1. 26E-08 2. 36E-04 O.OOE+OO 1.00E+00 

8.00E+03 1.04E-08 2. 48E-04 O.OOE+OO 1.00E+00 

B-631 
INGESTION £1= 3.00E-04 STABLE ERBIUM 167 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 8. 72E-OS 9.99E-OI 9.99E-OI 

2.00E-Ol 1.70E-04 9. 94E-Ol 9.94E-OI 

3.00E-Ol 2.13E-04 9.80E-OI 9.8IE-OI 

4.00E-Ol 2. 33E-04 9.S8E-Ol 9.S8E-OI 

S.OOE-Ol 2.40E-04 9.28E-Ol 9. 28E-Ol 

6.00E-OI 2.42E-04 8.9IE-OI 8. 92E-OI 

7.00E-Ol 2.40E-04 8.S0E-OI 8.SlE-Ol 

8.00E-Ol 2. 38E-04 8.06E-OI 8.06E-Ol 

-9.00E-OI 2. 36E-04 7.60E-OI 7.60E-OI 

I.OOE+OO 2. 34E-04 7.l3E-OI 7.I3E-OI 

2.00E+OO 2. 26E-04 3. 24E-Ol 3.24E-Ol 

3.00E+OO 2.2SE-04 I.29E-Ol 1.29E-Ol 

4.00E+OO 2.2SE-04 4. 89E-02 4.9"IE-02 

S.OOE+OO 2.2SE-04 I. 82E-02 I.84E-02 

6.00E+OO 2.2SE-04 6. 74E-03 6.97E-03 

7.00E+OO 2.2SE-04 2. 49E-03 2.7IE-03 

8.00E+OO 2.2SE-04 9.1SE-04 1. 14E-03 

9.00E+OO 2.2SE-04 3. 37E-04 S.62E-04 

I.OOE+Ol 2.2SE-04 1. 24E-04 3. 49E-04 

2.00E+Ol 2. 24E-04 O.OOE+OO 2. 24E-04 

3.00E+Ol 2. 24E-04 O.OOE+OO 2. 24E-04 

4.00E+OI 2. 23E-04 O.OOE+OO 2. 23E-04 

S.OOE+Ol 2. 23E-04 O.OOE+OO 2. 23E-04 

6.00E+Ol 2. 22E-04 O.OOE+OO 2. 22E-04 

7.00E+Ol 2. 22E-04 O.OOE+OO 2. 22E-04 

8.00E+Ol 2.21E-04 O.OOE+OO 2.21E-04 

9.00E+Ol 2.21E-04 O.OOE+OO 2.2lE-04 

I.OOE+02 2.2lE-04 O.OOE+OO 2.2IE-04 

2.00E+02 2.l6E-04 O.OOE+OO 2.16E-04 

3.00E+02 2.I2E-04 O.OOE+OO 2.I2E-04 

4.00E+02 2.08E-04 O.OOE+OO 2.08E-04 

S.OOE+02 2.04E-04 O.OOE+OO 2.04E-04 

6.00E+02 2.00E-04 O.OOE+OO 2.00E-04 

7.00E+02 1. 96E-04 O.OOE+OO 1. 96E-04 

8.00E+02 1.92E-04 O.OOE+OO 1. 92E-04 

9.00E+02 l.88E-04 O.OOE+OO 1. 88E-04 -." .. 1.00E+03 1.8SE-04 O.OOE+OO 1.8SE-04 

2.00E+03 I.SlE-04 O.OOE+OO 1.SIE-04 

3.00E+03 1. 24E-04 O.OOE+OO 1. 24E-04 

4.00E+03 I.02E-04 O.OOE+OO I.02E-04 

S.OOE+03 8. 36E-OS O.OOE+OO 8. 36E-OS 

7.00E+03 S.63E-OS O.OOE+OO S.63E-OS 

8.00E+03 4. 62E-OS O.OOE+OO 4. 62E-05 

9.00E+03 3. 79E-OS O.OOE+OO 3. 79E-05 

l.OOE+04 3.llE-OS O.OOE+OO 3.llE-OS 

2.00E+04 4. 29E-06 O.OOE+OO 4. 29E-06 

B-632 
INGESTION £1= 3.00E-04 STABLE ERBIUM 167 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED . 24-HOUR ACC ill'lULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 2.3BE-06 6.lOE-04 

2.00E-Ol 1.03E-OS 5.90E-03 

3.00E-Ol 2.06E-OS 1. 94E-02 

4.00E-01 3.0BE-OS 4. 16E-02 

S.OOE-OI 3. 99E-OS 7.lSE-02 

6.00E-Ol 4.7SE-OS 1.08E-Ol 

7.00E-Ol S.37E-OS I.49E-Ol 

B.OOE-OI S.S6E-OS 1.94E-OI 

9.00E-OI 6. 24E-OS 2.40E-Ol 

I.OOE+OO 6.S4E-OS 6. 54E-OS 2.B6E-OI 2.S6E-Ol 

2.00E+OO 9.0SE-06 7. 45E-OS 3.90E-OI 6. 76E-Ol 

3.00E+OO 6. 24E-07 7.SIE-OS 1.9SE-Ol B.71E-Ol 

4.00E+OO B.OBE-OB 7. S2E-OS 7.9BE-02 9. SlE-Ol 

S.OOE+OO 4. 68E-08 7.S2E-OS 3.07E-02 9.8lE-Ol 

6.00E+OO 4.46E-OS 7.S3E-OS 1.lSE-02 9.93E-Ol 

7.00E+OO 4.4SE-08 7.S3E-OS 4. 26E-03 9. 97E-Ol 

S.OOE+OO 4.4SE-OB 7.S3E-OS 1. S7E-03 9. 99E-01 

9.00E+OO 4.4SE-OB 7.S4E-OS S.79E-04 9.99E-Ol 

I.OOE+Ol 4.4SE-OS 7.S4E-OS 2. 13E-04 1.00E+OO 

2.00E+Ol 4.44E-OB 7.S9E-OS O.OOE+OO 1.00E+OO 

3.00E+Ol 4. 43E-OS 7. 63E-OS O.OOE+OO 1.OOE+OO 

4.00E+Ol 4. 42E-OB 7.6BE-OS O.OOE+OO 1.00E+OO 

S.OOE+Ol 4.4lE-OS 7.72E-OS O.OOE+OO 1.OOE+OO 

6.00E+Ol 4.40E-OB 7.76E-OS O.OOE+OO 1.OOE+OO 

7.00E+Ol 4. 39E-OS 7.BlE-OS O.OOE+OO 1.00E+OO 

B.OOE+Ol 4. 39E-OB 7. BSE-OS O.OOE+OO I.OOE+OO 

9.00E+Ol 4.3BE-OB 7.90E-OS O.OOE+OO 1.00E+OO 

1.OOE+02 4. 37E-08 7.94E-OS O.OOE+OO 1.OOE+OO 

2.00E+02 4.2SE-OS B.37E-OS O.OOE+OO 1.OOE+OO 

3.00E+02 4.20E-OB 8. BOE-OS O.OOE+OO 1.00E+OO 

4.00E+02 4.l2E-OB 9.2IE-OS O.OOE+OO 1.00E+OO 

S.OOE+02 4.04E-OB 9. 62E-OS O.OOE+OO 1.00E+OO 

6.00E+02 3. 96E-OS 1.00E-04 O.OOE+OO 1.00E+OO 

7.00E+02 3. SSE-OS 1.04E-04 O.OOE+OO 1.00E+OO 

8.00E+02 3. BOE-OB 1.OBE-04 O.OOE+OO 1.00E+OO 

9.00E+02 3. 73E-08 1. 12E-04 O.OOE+OO I.OOE+OO 

1.00E+03 3. 66E-OS 1.ISE-04 O.OOE+OO 1.00E+OO 

2.00E+03 3.00E-OB 1.49E-04 O.OOE+OO 1.00E+OO 

3.00E+03 2. 46E-OB 1.76E-04 O.OOE+OO 1.00E+OO 

4.00E+03 2.02E-08 1.9BE-04 O.OOE+OO 1.00E+OO 

S.OOE+03 1. 66E-OS 2. 16E-04 O.OOE+OO 1.00E+OO 

6.00E+03 1. 36E-08 2.3lE-04 O.OOE+OO 1.OOE+OO 

7.00E+03 1. llE-OB 2.44E-04 O.OOE+OO 1.OOE+OO 

B-633 
INGESTION fl"" 3.00E-04 STABLE YTTERBIUM 173 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------

SYSTEMIC G1 TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 8.60E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1.65E-04 9.94E-Ol 9.94E-Ol 

3.00E-Ol 2.03E-04 9.80E-0l 9.81E-Ol 

4.00E-Ol 2. 16E-04 9.58E-Ol 9. 58E-Ol 

5.00E-Ol 2. 17E-04 9.28E-Ol 9. 28E-Ol 

6.00E-Ol 2. 13E-04 8.9lE-01 8. 92E-Ol 

7.00E-Ol 2.07E-04 S.50E-Ol 8. 51E-Ol 

8.00E-Ol 2.01E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 1.95E-04 7.60E-Ol 7.60E-0l 

1.00E+00 1. 89E-04 7. 13E-Ol 7. 13E-Ol 

2.00E+00 1.68E-04 3.24E-Ol 3. 24E-Ol 

3.00E+00 1. 66E-04 1.29E-Ol 1.29E-Ol 

4.00E+00 1. 65E-04 4. 89E-02 4.90E-02 

5.00E+00 1. 65E-04 1. 82E-02 1. 84E-02 

6.00E+00 1.64E-04 6.74E-03 6.91E-03 

7.00E+00 1.64E-04 2.49E-03 2. 65E-03 

8.00E+00 1. 64E-04 9.15E-04 1.08E-03 

9.00E+00 1. 63E-04 3. 37E-04 5.00E-04 

1.00E+Ol 1. 63E-04 1.24E-04 2. 87E-04 

2.00E+Ol 1.61E-04 O.OOE+OO 1.61E-04 

3.00E+Ol 1.60E-04 O.OOE+OO 1.6 

4.00E+Ol 1.60E-04 O.OOE+OO 1.60E 

5.00E+Ol 1.59E-04 O.OOE+OO 1.59E6.00E+Ol 1.59E-04 O.OOE+OO 1. 59E-04 

7.00E+Ol 1. 58E-04 O.OOE+OO 1. 58E-04 

8.00E+Ol 1. 58E-04 O.OOE+OO 1. 58E-04 

9.00E+Ol 1. 58E-04 O.OOE+OO 1.58E-04 

1.00E+02 1. 57E-04 O.OOE+OO 1. 57E-04 

2.00E+02 1. 54E-04 O.OOE+OO 1.54E-04 

3.00E+02 1.51E-04 O.OOE+OO 1.51E-04 

4.00E+02 1. 48E-04 O.OOE+OO 1.48E-04 

5.00E+02 1. 45E-04 O.OOE+OO 1.45E-04 

6.00E+02 1. 43E-04 O.OOE+OO 1.43E-04 

7.00E+02 1.40E-04 O.OOE+OO 1.40E-04 

8.00E+02 1.37E-04 O.OOE+OO 1. 37E-04 

9.00E+02 1. 34E-04 O.OOE+OO 1. 34E-04 

1.00E+03 1.32E-04 O.OOE+OO 1. 32E-04 

2.00E+03 1.08E-04 O.OOE+OO 1.08E-04 

3.00E+03 8.86E-05 O.OOE+OO 8.86E-05 

4.00E+03 7. 27E-05 O.OOE+OO 7. 27E-05 

5.00E+03 5. 96E-05 O.OOE+OO 5. 96E-05 

7.00E+03 4.01E-05 O.OOE+OO 4.01E-05 

8.00E+03 3. 29E-05 O.OOE+OO 3. 29E-05 

9.00E+03 2.70E-05 O.OOE+OO 2.70E-05 

1.00E+04 2. 22E-05 O.OOE+OO 2. 22E-05 

2.00E+04 3.06E-06 O.OOE+OO 3.0 

B-634 
INGESTION £1"" 3.00E-04 STABLE tTTERBIUM 173 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3. S2E-06 6.10E-04 

2.00E-OI I. SSE-OS S.90E-03 

3.00E-OI 3.14E-OS 1. 94E-02 

4.00E-OI 4. 78E-OS 4.l6E-02 

S.OOE-Ol 6. 28E-OS 7.l8E-02 

6.00E-Ol 7. 59E-OS I.08E-OI 

7.00E-Ol 8. 69E-OS 1.49E-Ol 

8.00E-Ol 9.6lE-OS l.94E-Ol 

9.00E-Ol I.04E-04 2.40E-OI 

1.OOE+OO 1.lOE-04 l.lOE-04 2. 86E-Ol 2. 86E-Ol 

2.00E+OO 2.2lE-OS 1. 32E-04 3.90E-Ol 6.76E-Ol 

3.00E+OO 2. 66E-06 1. 34E-04 1.9SE-Ol 8.71E-OI 

4.00E+OO S.97E-07 1.3SE-04 7.98E-02 9.SlE-Ol 

S.OOE+OO 3.6SE-07 1.3SE-04 3.07E-02 9.8IE-Ol 

6.00E+OO 3. 22E-07 I. 36E-04 1.lSE-02 9. 93E-Ol 

7.00E+OO 3.0lE-07 1. 36E-04 4. 26E-03 9.97E-Ol 

8.00E+OO 2.83E-07 1. 36E-04 1. S7E-03 9.99E-Ol 

9.00E+OO 2. 66E-07 1. 37E-04 S.79E-04 9.99E-OI 

1.OOE+Ol 2.S0E-07 1. 37E-04 2.l3E-04 1.OOE+OO 

2.00E+Ol 1.4lE-07 1. 39E-04 O.OOE+OO 1.OOE+OO 

3.00E+Ol 8. 62E-08 1.40E-04 O.OOE+OO 1.OOE+OO 

4.00E+Ol S.89E-08 1~40E-04 O.OOE+OO I.OOE+OO 

S.OOE+Ol 4.S1E-08 1.4IE-04 O.OOE+OO 1.00E+OO 

6.00E+Ol 3.82E-08 1.41E-04 O.OOE+OO 1.00E+OO 

7.00E+Ol 3. 48E-08 1. 42E-04 O.OOE+OO 1.00E+OO 

8.00E+Ol 3.30E-08 1. 42E-04 O.OOE+OO 1.00E+OO. 

9.00E+Ol 3.2lE-08 1. 42E-04 O.OOE+OO 1.00E+OO 

1.OOE+02 3. 16E-08 1. 43E-04 O.OOE+OO 1.00E+OO 

2.00E+02 3.0SE-08 1. 46E-04 O.OOE+OO 1.00E+OO 

3.00E+02 3.00E-08 1. 49E-04 O.OOE+OO 1.00E+OO 

4.00E+02 2. 94E-08 1. S2E-04 O.OOE+OO 1.OOE+OO 

S.OOE+02 2. 88E-08 I.SSE-04 O.OOE+OO 1.00E+OO 

6.00E+02 2. 82E-08 I.S7E-04 O.OOE+OO 1.OOE+OO 

7.00E+02 2.77E-08 1.60E-04 O.OOE+OO 1.00E+OO 

8.00E+02 2.7IE-08 1. 63E-04 O.OOE+OO 1.OOE+OO 

9.00E+02 2. 66E-08 I. 66E-04 O.OOE+OO 1.00E+OO 

1.00E+03 2.61E-08 1. 68E-04 O.OOE+OO 1.OOE+OO 

2.00E+03 2. 14E-08 1. 92E-04 O.OOE+OO 1.00E+OO 

3.00E+03 1.7SE-08 2.11E-04 O.OOE+OO I.OOE+OO 

4.00E+03 1. 44E-08 2. 27E-04 O.OOE+OO 1.OOE+OO 

S.OOE+03 1.18E-08 2.40E-04 O.OOE+OO 1.OOE+OO 

B-635 
INGESTION fl= 3.00E-04 STABLE LUTETIUM 175 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI B.66E-05 9. 99E-OI 9.99E-OI 

2.00E-OI 1. 67E-04 9. 94E-OI 9.94E-OI 

3.00E-OI 2.0BE-04 9.BOE-OI 9.BIE-OI 

4.00E-OI 2. 24E-04 9.5BE-OI 9.5BE-OI 

5.00E-OI 2. 27E-04 9.2BE-OI 9.2BE-OI 

6.00E-OI 2. 25E-04 8.9IE-OI B.92E-OI 

7.00E-OI 2.2IE-04 B.50E-OI B.5IE-0l 

B.OOE-OI 2.16E-04 B.06E-Ol B.06E-OI 

9.00E-OI 2.IIE-04 7.60E-OI 7.60E-0l 

I.OOE+OO 2.07E-04 7.l3E-OI 7.l3E-OI 

2.00E+OO I.B9E-04 3. 24E-OI 3. 24E-OI 

3.00E+OO I. 87E-04 1. 29E-OI 1. 29E-OI 

4.00E+OO 1. B7E-04 4. 89E-02 4.9IE-02 

5.00E+OO I.B7E-04 1. 82E-02 I. 84E-02 

6.00E+OO I.B7E-04 6. 74E-03 6. 93E-03 

7.00E+OO I.B7E-04 2. 49E-03 2. 67E-03 

B.OOE+OO I.B7E-04 9.15E-04 1. IOE-03 

9.00E+OO I.B6E-04 3. 37E-04 5. 23E-04 

I.OOE+OI I.B6E-04 1.24E-04 3. IOE-04 

2.00E+OI I.B6E-04 O.OOE+OO I.B6E-04 

3.00E+OI I.B5E-04 .O.OOE+OO 1. B5E-04 

4.00E+OI I.B5E-04 O.OOE+OO I.B5E-04 

5.00E+OI 1. B4E-04 O.OOE+OO I.B4E-04 

6.00E+OI I.B4E-04 O.OOE+OO 1 .. 84E-04 

7.00E+OI I.B3E-04 O.OOE+OO 1 .. 83E-04 

8.00E+OI 1. 83E-04 O.OOE+OO I.B3E-04 

9.00E+OI I.B3E-04 O.OOE+OO 1. 83E-04 

I.OOE+02 I.B2E-04 O.OOE+OO I.B2E-04 

2.00E+02 1. 79E-04 O.OOE+OO 1. 79E-04 

3.00E+02 1. 75E-04 O.OOE+OO 1. 75E-04 

4.00E+02 1.72E-04 O.OOE+OO 1.72E-04 

5.00E+02 1. 68E-04 O.OOE+OO 1. 68E-04 

6.00E+02 1.65E-04 O.OOE+OO 1. 65E-04 

7.00E+02 1. 62E-04 O.OOE+OO 1. 62E-04 

8.00E+02 1.59E-04 O.OOE+OO 1. 59E-04 

9.00E+02 I .. 56E-04 O.OOE+OO 1. 56E-04 

I.OOE+03 1.53E-04 O.OOE+OO 1.53E-04 

2.00E+03 1. 25E-04 O.OOE+OO 1. 25E-04 

3.00E+03 I.03E-04 O.OOE+OO I.03E-04 

4.00E+03 8.42E-05 O.OOE+OO 8.42E-05 

5.00E+03 6.9IE-05 O.OOE+OO 6.9IE-05 

7.00E+03 4. 65E-05 O.OOE+OO 4. 65E-05 

B.OOE+03 3. 82E-05 O.OOE+OO 3. 82E-05 

9.00E+03 3.l3E-05 O.OOE+OO 3.l3E-OS 

1.00E+04 2. 57E-OS O.OOE+OO 2. 57E-OS 

2.00E+04 3.S5E-06 O.OOE+OO 3. 55E-06 

8-636 
INGESTION fl= 3.00E-04 STABLE LUTETIUM 175 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 2. 97E-06 6.l0E-04 

2.00E-Ol 1.30E-05 5.90E-03 

3.00E-Ol 2. 65E-05 1. 94E-02 

4.00E-Ol 4.02E-05 4.l6E-02 

5.00E-Ol 5. 29E-05 7.l8E-02 

6.00E-Ol 6. 39E-05 1.08E-Ol 

7.00E-Ol 7.3lE-05 1.49E-Ol 

8.00E-Ol 8.08E-05 1. 94E-Ol 

9.00E-Ol 8.7lE-05 2.40E-Ol 

1.OOE+OO 9. 22E-05 9.22E-05 2.B6E-Ol 2.B6E-Ol 

2.00E+OO 1.B4E-05 1.11E-04 3.90E-Ol 6.76E-Ol 

3.00E+OO 2.04E-06 1.13E-04 1. 95E-Ol B.71E-Ol 

4.00E+OO 3.l7E-07 1.13E-04 7.9BE-02 9.5lE-0l 

5.00E+OO 1. 34E-07 1.13E-04 3.07E-02 9.BlE-Ol 

6.00E+OO 1. 11E-07 1.13E-04 1.15E-02 9. 93E-Ol 

7.00E+OO 1.04E-07 1.l3E-04 4. 26E-03 9. 97E-Ol 

B.OOE+OO 9. 95E-OB 1. 13E-04 1.57E-03 9.99E-Ol 

9.00E+OO 9. 53E-OB 1.14E-04 5. 79E-04 9. 99E-Ol 

1.OOE+Ol 9.l4E-OB 1.14E-04 2.l3E-04 1.OOE+OO 

2.00E+Ol 6.40E-OB 1.14E-04 O.OOE+OO 1.OOE+OO 

3.00E+0l 5.03E-OB 1.15E-04 O.OOE+OO 1.OOE+OO 

4.00E+Ol 4. 34E-OB 1.15E-04 ·O.OOE+OO 1.OOE+OO 

5.00E+Ol 3.99E-OB 1.16E-04 O.OOE+OO 1.OOE+OO 

6.00E+Ol 3. BlE-OB 1.16E-04 O.OOE+OO 1.OOE+OO 

7.00E+Ol 3. 72E-OB 1.17E-04 O.OOE+OO 1.OOE+OO 

B.OOE+Ol 3. 67E-08 1.17E-04 O.OOE+OO 1.OOE+OO 

9.00E+Ol 3. 64E-OB 1.17E-04 O.OOE+OO 1.OOE+OO 

1.OOE+02 3. 62E-OB 1.lBE-04 O.OOE+OO 1.OOE+OO 

2.00E+02 3.54E-OB 1.2lE-04 O.OOE+OO 1.OOE+OO 

3.00E+02 3. 47E-OB 1. 25E-04 O.OOE+OO 1.OOE+OO 

4.00E+02 3.40E-OB 1.2BE-04 O.OOE+OO 1.OOE+OO 

5.00E+02 3. 34E-OB 1. 32E-04 O.OOE+OO 1.OOE+OO 

6 .• 00E+02 3. 27E-OB 1.35E-04 O.OOE+OO 1.OOE+OO 

7.00E+02 3.21E-OB 1.3BE-04 O.OOE+OO 1.OOE+OO 

B.OOE+02 3.l4E-OB 1.4lE-04 O.OOE+OO 1.OOE+OO 

9.00E+02 3.0BE-OB 1. 44E-04 O.OOE+OO 1.OOE+OO 

1.OOE+03 3.02E-OB 1. 47E-04 O.OOE+OO 1.OOE+OO 

2.00E+03 2.4BE-QB 1. 75E-04 O.OOE+OO 1.OOE+OO 

3.00E+03 2.03E-OB 1. 97E-04 O.OOE+OO 1.OOE+OO 

4.00E+03 1. 67E-OB 2.l6E-04 O.OOE+OO 1.OOE+OO 

5.00E+03 1. 37E-OB 2.3lE-04 O.OOE+OO 1.OOE+OO 

6.00E+03 1.12E-OB 2. 43E-04 O.OOE+OO 1.OOE+OO 

B-637 
INGESTION f 1= 2.00E-03 STABLE HAFNIUM 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 5.97E-04 9.99E-0l 9. 99E-Ol 

2.00E-Ol 1.20E-03 9. 93E-Ol 9. 94E-Ol 

3.00E-0l ' 1.55E-03 9. 79E-Ol 9.8lE-Ol 

4.00E-Ol 1. 74E-03 9.57E-Ol 9.58E-Ol 

5.00E-Ol 1. 84E-03 9. 26E-Ol 9. 28E-Ol 

6.00E-Ol 1. 89E-03 8.90E-Ol 8. 92E-Ol 

7.00E-Ol 1.9lE-03 8. 49E-Ol 8. 51E-0l 

8.00E-Ol 1. 92E-03 8.05E-Ol 8.06E-Ol 

9.00E-0l 1.92E-03 7. 59E-Ol 7.60E-Ol 

1.OOE+OO 1. 92E-03 7. 12E-Ol 7.14E-Ol 

2.00E+OO 1. 84E-03 3. 23E-Ol 3. 25E-Ol 

3.00E+OO 1.76E-03 1. 28E-Ol 1.30E-Ol 

4.00E+OO 1. 69E-03 4. 88E-02 5.05E-02 

5.00E+OO 1. 62E-03 1. 82E-02 1. 98E-02 

6.00E+OO 1.56E-03 6. 73E-03 8. 29E-03 

7.00E+OO 1.51E-03 2. 48E-03 3. 99E-03 

8.00E+OO 1. 46E-03 9. 14E-04 2. 38E-03 

9.00E+OO 1.42E-03 3. 36E-04 1. 75E-03 

1.OOE+Ol 1. 38E-03 1.24E-04 1.50E-03 

2.00E+Ol l.l4E-03 O.OOE+OO 1. 14E-03 

3.00E+Ol 1.05E-03 O.OOE+OO 1.05E-03 

4.00E+Ol 1.02E-03 O.OOE+OO 1.0ZE-03 

5.00E+Ql 1.00E-03 O.OOE+OO 1.OOE-03 

6.00E+Ol 9. 98E-04 O.OOE+OO 9. 98E-04 

7.00E+Ol 9.95E-04 O.OOE+OO 9.95E-04 

8.00E+Ol 9. 93E-04 O.OOE+OO 9. 93E-04 

9.00E+Ol 9. 92E-04 O.OOE+OO 9~92E-04 

1.OOE+02 9.9lE-04 O.OOE+OO 9.9lE-04 

2.00E+02 9. 83E-04 O.OOE+OO 9. 83E-04 

3.00E+02 9. 74E-04 O.OOE+OO 9. 74E-04 

4.00E+02 9. 66E-04 O.OOE+OO 9. 66E-04 

5.00E+02 9. 58E-04 O.OOE+OO 9. 58E-04 

6.00E+02 9. 49E-04 O.OOE+OO 9.49E-04 

7.00E+02 9.41E-04 O.OOE+OO 9.41E-04 

8.00E+02 9.33E-04 O.OOE+OO 9.33E-04 

9.00E+02 9. 25E-04 O.OOE+OO 9. 25E-04 

1.00E+03 9.l7E-04 O.OOE+OO 9. 17E-04 

2.00E+03 8.41E-04 O.OOE+OO 8.41E-04 

3.00E+03 7. 71E-04 O.OOE+OO 7.71E-04 

4.00E+03 7.07E-04 O.OOE+OO 7.07E-04 

5.00E+03 6. 48E-04 O.OOE+OO 6. 48E-04 

7.00E+03 5.45E-04 O.OOE+OO 5. 45E-04 

8.00E+03 5.00E-04 O.OOE+OO 5.00E-04 

9.00E+03 4. 59E-04 O.OOE+OO 4. 59E-04 

1.OOE+04 4. 21E-04 O.OOE+OO 4.Z1E-04 

2.00E+04 1.77E-04 O.OOE+OO 1.77E-04 

B-638 
INGESTION f 1- 2.00E-ol STABLE BAPNIDM 179 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE"'Ol 1. 22E-06 6.09E-04 

2.00E-Ol S.77E-06 S.90E-03 

3.00E-Ol 1. 26E-OS 1. 93E-02 

4.00E-Ol 2.07E-OS 4.16E-02 

S.OOE-Ol 2.9SE-OS 7.17E-02 

6.00E-Ol 3.S6E-OS 1.OSE-Ol 

7.00E-Ol 4.7SE-OS 1.49E-Ol 

S.OOE-Ol S.70E-05 1. 93E-OI 

9.00E-Ol 6. 62E-OS 2. 39E-Ol 

1.OOE+OO 7. 54E-05 7.S4E-OS 2.S6E-Ol 2.S6E-Ol 

2.00E+OO S.72E-OS 1.63E-04 3.S9E-OI 6.7SE-Ol 

3.00E+OO 7.90E-OS 2. 42E-04 1.94E-Ol S.70E-Ol 

4.00E+OO 7.l6E-05 3.l3E-04 7.97E-02 9. 49E-Ol 

S.OOE+OO 6.49E-OS 3.7SE-04 3.06E-02 9. SOE-O 1 

6.00E+OO S.S7E-OS 4.37E-04 1.lSE-02 9.9IE-OI 

7.00E+OO S.32E-OS 4.90E-04 4.2SE-03 9. 96E-OI 

S.OOE+OO 4.S2E-OS S.3SE-04 I.S7E-03 9.97E-Ol 

9.00E+OO 4. 37E-OS S.S2E-04 S.77E-04 9.9SE-OI 

1.OOE+Ol 3. 96E-OS 6.2IE-04 2.l3E-04 9.9SE-Ol 

2.00E+Ol I.48E-OS 8.6lE-04 O.OOE+OO 9. 98E-Ol 

3.00E+Ol S.S4E-06 9.S0E-04 O.OOE+OO 9. 98E-OI 

4.00E+OI 2.IlE-06 9. 84E-04 O.OOE+OO 9.98E-Ol 

S.OOE+Ol 8. 39E-07 9. 97E-04 O.OOE+OO 9.98E-Ol 

7.00E+OI 1.90E-07 1.OlE-03 O.OOE+OO 9. 98E-Ol 

8.00E+Ol 1.2SE-07 I.OIE-03 O.OOE+OO 9. 98E-Ol 

9.00E+Ol I.OOE-07 1.OlE-03 O.OOE+OO 9.98E-Ol 

1.OOE+02 9.12E-08 1.OIE-03 O.OOE+OO 9. 98E-OI 

2.00E+02 8.SlE-08 I.02E-03 O.OOE+OO 9. 98E-Ol 

3.00E+02 8. 44E-08 1.03E-03 O.OOE+OO 9. 98E-Ol 

4.00E+02 8. 37E-08 1.03E-03 O.OOE+OO 9.9BE-Ol . S.OOE+02 B.30E-08 1.04E-03 O.OOE+OO 9.9BE-Ol 

7.00E+02 B.ISE-OS 1.06E-03 O.OOE+OO 9. 98E-Ol 

B.OOE+02 B.08E-08 1.07E-03 O.OOE+OO 9.9BE-Ol 

9.00E+02 B.OlE-OB 1.07E-03 O.OOE+OO 9.9BE-Ol 

1.OOE+03 7. 94E-OS 1.OBE-03 O.OOE+OO 9.9BE-Ol 

2.00E+03 7.2BE-OB 1.16E-03 O.OOE+OO 9.9BE-Ol 

3.00E+03 6.6SE-OB 1. 23E-03 O.OOE+OO 9.9BE-OI 

4.00E+03 6.13E-08 1.29E-03 O.OOE+OO 9.9BE-Ol 

S.OOE+03 S.62E-OB 1.3SE-03 O.OOE+OO 9.9BE-Ol 

7.00E+03 4. 72E-OB 1.4SE-03 O.OOE+OO 9.9BE-Ol 

S.OOE+03 4. 33E-OS 1.SOE-03 O.OOE+OO 9.9SE-Ol 

9.00E+03 3. 97E-OS I.54E-03 O.OOE+OO 9.9BE-Ol 

I.OOE+04 3. 64E-OS 1.5BE-03 O.OOE+OO 9.9SE-OI 

2.00E+04 1.S3E-OB 1.S2E-03 O.OOE+OO 9.9BE-Ol 

B-639 
INCESTION f 1'= 2.00£-03 BALlLlFE= 4.24£+01 DAYS IlAP'NIUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5. 96E-04 9. 97E-Ol 9.9SE-Ol 

2.00E-Ol 1.19E-03 9.90E-Ol 9.9lE-Ol 

3.00E-Ol l.54E-03 9.74E-0l 9.76E-Ol 

4.00E-Ol l.73E-03 9.50E-Ol 9. 52E-Ol 

5.00E-Ol 1~S2E-03 9.l9E-Ol 9.2lE-Ol 

6.00E-Ol 1.S7E-03 S.SlE-Ol S.S3E-Ol 

7.00E-0l 1.S9E-03 S.39E-Ol S.4lE-Ol 

S.OOE-Ol l.90E-03 . 7. 94E-Ol 7. 96E-Ol 

9.00E-Ol 1.S9E-03 7. 47E-Ol 7.49E-Ol 

l.OOE+OO 1.S9E-03 7.00E-Ol 7.02E-Ol 

2.00E+OO 1.7SE-03 3.13E-Ol 3.l4E-Ol 

3.00E+00 1. 67E-03 1. 22E-Ol 1. 24E-Ol 

4.00E+OO 1.5SE-03 . 4. 57E-02 4. 73E-02 

5.00E+OO l.49E-03 1.68E 02 1.S3E-02 

6.00E+OO 1. 42E-03 6.lOE-03 7. 52E-03 

7.·00E+OO 1. 35E-03 2.2lE-03 3. 56E-03 

S.OOE+OO 1. 28E-03 8.02E-04 2.0SE-03 

9.00E+OO 1. 22E-03 2.90E-04 l.5lE-03 

1.OOE+Ol 1.17E-03 1.05E-04 1.2SE-03 

2.00E+Ol 8. 22E-04 O.OOE+OO 8. 22E-04 

3.00E+Ol 6. 43E-04 O.OOE+OO 6. 43E-04 

4.00E+Ol 5. 28E-04 O.OOE+OO 5. 28E-04 

5.00E+Ol 4. 43E-04 O.OOE+OO 4. 43E-04 

6.00E+Ol 3. 74E-04 O.OOE+OO 3. 74E-04 

7.00E+Ol 3.l7E-04 O.OOE+OO 3.l7E-04 

S.OOE+Ol 2. 69E-04 O.OOE+OO 2. 69E-04 

9.00E+Ol 2.2SE-04 O.OOE+OO 2.2SE-04 

1.OOE+02 1. 93E-04 O.OOE+OO 1. 93E-04 

2.00E+02 3. 74E-05 O.OOE+OO 3. 74E-05 

3.00E+02 7.22E-06 O.OOE+OO 7. 22E-06 

4.00E+02 1.40E-06 O.OOE+OO 1.40E-06 

5.00E+02 2.70E-07 O.OOE+OO 2. 7 OE-O 7 

6.00E+02 5. 22E-OS O.OOE+OO 5. 22E-OS 

7.00E+02 1.OlE-OS O.OOE+OO 1.OlE-08 

.. " 

.. 

B-640 
IBGESTIOM f 1- 2.00K-03 BALFLI!'K... 4.24E+Ol DAYS BAPBIOM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 1. 22E-06 6.06E-04 

2.00E-OI 5. 75E-06 5. 66E-03 

3.00E-OI I.25E-05 I.92E-02 

4.00E-OI 2.06E-05 4.13E-02 

5.00E-OI 2. 92E-05 7.IIE-02 

6.00E-OI 3. 62E-05 I.07E-OI 

7.00E-OI 4.12E-05 1. 46E-OI 

8.00E-OI 5. 63E-05 1.9IE-OI 

9.00E-0l 6. 53E-05 2. 36E-OI 

I.OOE+OO 7. 42E-05 7.42E-05 2.6lE-OI 2.6IE-OI 

2.00E+OO 6. 44E-05 1.57E-04 3.76E-OI 6. 53E-OI 

3.00E+OO 7. 53E-05 2.30E-04 1. 65E-OI 6. 28E-OI 

4.00E+OO 6.71E-05 2. 93E-04 7.46E-02 6.69E-OI 

5.00E+OO 5. 96E-05 3. 46E-04 2. 62E-02 9.03E-OI 

6.00E+OO 5. 33E-05 3. 96E-04 I.04E-02 6.99E-OI 

7.00E+OO 4. 75E-05 4. 37E-04 3. 79E-03 6. 66E-OI 

6.00E+OO 4.23E-05 4. 12E-04 1. 36E-03 8. 75E-OI 

9.00E+OO 3.17K-05 5.02E-04 4.96E-04 8.6IE-OI 

I.OOE+OI 3. 36E-05 5. 26E-04 I.80E-04 8. 47E-OI 

2.00E+OI I.06E-05 6.2IE-04 O.OOE+OO 7.20E-OI 

3.00E+OI 3. 39E-06 5. 82E-04 O.OOE+OO 6.11E-0l 

4.00E+OI 1.IOE-06 5.12E-04 O.OOE+OO 5.19E-OI 

5.00E+OI 3.70E-07 4.40E-04 O.OOE+OO 4.4IE-OI 

6.00E+OI 1. 37E-07 3. 76E-04 O.OOE+OO 3. 74E-OI 

7.00E+OI 6.05E-08 3.20E-04 O.OOE+OO 3.16E-OI 

8.00E+OI 3. 37E-08 2. 12E-04 O.OOE+OO 2.70E-OI 

9.00E+OI 2.30E-06 2.3IE-04 O.OOE+OO 2.29E-OI 

I.OOE+02 1. 76E-06 1. 97E-04 O.OOE+OO . 1. 95E-OI 

,.; 

'. ::. " ; .' 

B-641 
INGESTION fl= 1.00E-Q3 STABLE TANTALUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2. 98E-04 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol S.98E-04 9.93E-Ol 9.94E-Ol 

3.00E-Ol 7.72E-04 9.80E-Ol 9.8lE-Ol 

4.00E-Ol 8. 66E-04 9.S8E-Ol 9.S8E-Ol 

S.OOE-Ol 9.1SE-04 9.27E-Ol 9.28E-Ol 

6.00E-Ol 9. 39E-04 8.91E-Ol 8. 92E-Ol 

7.00E-Ol 9. 49E-04 8.S0E-Ol 8.SlE-0l 

8.00E-Ol 9.S2E-04 8.0SE-Ol 8.06E-Ol 

9.00E-Ol 9.SlE-04 7.S9E-Ol 7.60E-Ol 

1.OOE+OO 9.48E-04 7.l3E-Ol 7.l4E-Ol 

2.00E+OO 8. 99E-04 3. 23E-Ol 3.24E-Ol 

3.00E+OO 8.S3E-04 1. 29E-Ol 1.29E-Ol 

4.00E+OO 8.lSE-04 4. 88E-02 4. 96E-02 

S.OOE+OO 7.8lE-04 1. 82E-02 l.90E-02 

6.00E+OO 7.S3E-04 6. 74E-03 7.49E-03 

7.00E+OO 7. 28E-04 2. 48E-03 3.2lE-03 

8.00E+OO 7.07E-04 9.lSE-04 1.62E-03 

9.00E+OO 6. 88E-04 3. 37E-04 1.02E-03 

l.OOE+Ol 6.72E-04 1.24E-04 7.9SE-04 

2.00E+Ol S.78E-04 O.OOE+OO S.78E-04 

3.00E+Ol S.31E-04 O.OOE+OO S.3lE-04 

4.00E+Ol 4. 94E-04 O.OOE+OO 4. 94E-04 

S.OOE+Ol 4.60E-04 O.OOE+OO 4.60E-04 

6.00E+Ol 4.30E-04 O.OOE+OO 4.30E-04 

7.00E+Ol 4.01E-04 O.OOE+OO 4.01E-04 

8.00E+Ol 3. 74E-04 O.OOE+OO 3. 74E-04 

9.00E+Ol 3. 49E-04 O.OOE+OQ 3. 49E-04 

1.00E+02 3. 26E-04 O.OOE+OO 3. 26E-04 

2.00E+02 1.63E-04 O.OOE+OO 1. 63E-04 

3.00E+02 8.14E-OS O.OOE+OO 8.14E-OS 

4.00E+02 4.07E-OS O.OOE+OO 4.07E-OS 

S.OOE+02 2.04E-OS O.OOE+OO 2.04E-OS 

6.00E+02 1.02E-OS O.OOE+OO 1.02E-OS 

7.00E+02 S.09E-06 O.OOE+OO S.09E-06 

8.00E+02 2.SSE-06 O.OOE+OO 2.SSE-06 

9.00E+02 1. 27E-06 O.OOE+OO 1. 27E-06 

1.00E+03 6.37E-07 O.OOE+OO 6. 37E-07 

B-642 
INGESTION £1= 1.00K-03 STABLE TANTALUM 181 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 8.02E-07 6.10E-04 

2.00E-OI 3.77E-06 S.90E-03 

3.00E-OI 8. 23E-06 I. 93E-02 

4.00E-OI 1.3SE-OS 4.16E-02 

S.OOE-Ol 1. 92E-OS 7.17E-02 

6.00E-Ol 2.S0E-OS I.08E-OI 

7.00E-OI 3.09E-OS 1.49E-OI 

8.00E-OI 3. 67E-05 1. 94E-OI 

9.00E-Ol 4. 26E-05 2.40E-Ol 

I.OOE+OO 4. 83E-OS 4. 83E-OS 2. 86E-OI 2.86E-OI 

2.00E+OO S.30E-OS 1.OlE-04 3.89E-Ol 6. 76E-OI 

3.00E+OO 4.S3E-OS 1.47E-04 1.9SE-OI 8.1OE-OI 

4.00E+OO 3. 87E-OS 1.8SE-04 7. 98E-02 9.S0E-Ol 

S.OOE+OO 3. 32E-OS 2.19E-04 3.06E-02 9.8IE-OI 

6.00E+OO 2. 86E-OS 2.47E-04 l.lSE-02 9. 92E-OI 

7.00E+OO 2.47E-OS 2. 72E-04 4.2SE-03 9.97E-OI 

8.00E+OO 2.1SE-OS 2.93E-04 1. S7E-03 9. 98E-OI 

9.00E+OO 1.87E-OS 3.12E-04 S.78E-04 9.99E-OI 

I.OOE+OI I. 64E-OS 3. 28E-04 2. 13E-04 9. 99E-Ol 

2.00E+OI 6.09E-06 4. 22E-04 O.OOE+OO 9. 99E-Ol 

3.00E+OI 4.06E-06 4. 69E-04 O.OOE+OO 9.99E-OI 

4.00E+Ol 3.S0E-06 5.06E-04 O.OOE+OO 9. 99E-OI 

5.00E+OI 3.2IE-06 S.40E-04 O.OOE+OO 9. 99E-OI 

6.00E+Ol 2. 99E-06 S.70E-04 O.OOE+OO 9. 99E-OI 

7.00E+OI 2. 79E-06 S.99E-04 O.OOE+OO 9. 99E-Ol 

8.00E+OI 2.60E-06 6. 26E-04 O.OOE+OO 9. 99E-OI 

9.00E+OI 2. 43E-06 6.5IE-04 O.OOE+OO 9. 99E-Ol 

1.OOE+02 2. 26E-06 6. 74E-04 O.OOE+OO 9. 99E-Ol 

2.00E+02 1.13E-06 8. 37E-04 O.OOE+OO 9. 99E-OI 

3.00E+02 S.66E-07 9.19E-04 O.OOE+OO 9.99E-Ol 

4.00E+02 2. 83E-07 9.S9E-04 O.OOE+OO 9. 99E-Ol 

S.OOE+02 1. 42E-07 9.80E-04 O.OOE+OO 9. 99E-Ol 

6.00E+02 7.08E-08 9.90E-04 O.OOE+OO 9. 99E-OI 

7.00E+02 3.S4E-08 9.9SE-04 O.OOE+OO 9. 99E-OI 

8.00E+02 1.17E-08 9. 97E-04 O.OOE+OO 9. 99E-OI 

B-643 
INGESTION f l- 1.OOE-03 HALFLIFB-l.lSE+02 DAYS TANTALUM 182 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------

SYSTEtlIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2.98E-04 9.98E-Ol 9.99E-Ol 

2.00E-Ol S.97E-04 9.92E-Ol 9.93E-Ol 

3.00E-OI 7.7lE-04 9.78E-Ol 9.79E-Ol 

4.00E-Ol 8.64E-04 9.S5E-Ol 9.56E-Ol 

5.00E-Ol 9.l2E-04 9.25E-Ol 9.25E-Ol 

6.00E-Ol 9. 35E-04 8.88E-Ol 8.89E-Ol 

7.00E-OI 9.4SE-04 8.46E-Ol 8.47E-Ol 

8.00E-Ol 9.48E-04 8.02E-Ol 8.02E-Ol 

9.OOE-Ol 9.46E-04 7.S5E-Ol 7.S6E-OI 

l.OOE+OO 9.43E-04 7.08E-Ol 7.09E-Ol 

2.00E+OO 8.88E-04 3.l9E-Ol 3.20E-Ol 

3.00E+OO 8.38E-04 1.26E-Ol 1.27E-Ol 

4.00E+OO 7.95E-04 4.77E-02 4.85E-02 

5.00E+OO 7.S8E-04 1.77E-02 1.84E-02 

6.00E+OO 7.26E-04 6.50E-03 7.22E-03 

7.00E+OO 6.98E-04 2.38E-03 3.08E-03 

8.00E+OO 6.73E-04 8.72E-04 1.S4E-03 

9.00E+OO 6.S2E-04 3.l9E-04 9.70E-04 

l.OOE+Ol 6.32E-04 1.17E-04 7.49E-04 

2.00E+Ol S.12E-04 O.OOE+OO S.12E-04 

3.00E+Ol 4.43E-04 O.OOE+OO 4.4 

4.00E+Ol 3.88E-04 O.OOE+OO 3. 

5.0CE+Ol 3.4lE-04 O.OOE+OO 3.4 

6.00E+Ol 2.99E-04 O.OOE+OO 2.99E-04 

7.00E+Ol 2.63E-04 O.OOE+OO 2.63E-04 

8.00E+Ol 2.3lE-04 O.OOE+OO 2.3lE-04 

9.00E+Ol 2.03E-04 O.OOE+OO 2.03E-04 

1.OOE+02 1.78E-04 O.OOE+OO 1.78E-04 

2.00E+02 4.88E-OS O.OOE+OO 4.88E-OS 

3.00E+02 1.33E-OS O.OOE+OO l.33E-OS 

4.00E+02 3.6SE-06 O.OOE+OO 3.6SE-06 

5.00E+02 1.OOE-06 O.OOE+OO 1.OOE-06 

6.00E+02 2.74E-07 O.OOE+OO 2.74E-07 

7.00E+02 7.49E-08 O.OOE+OO 7.49E-08 

8.00E+02 2.0SE-08 O.OOE+OO 2.0SE-OS 

, .. 
lRGESTION fl'- 1.00E-03 BALPLIFE- 1.15E+02 DAYS TANTALUM 182 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-ol 8.02E-07 6.09E-04 

2.00E-Ol 3.77E-06 5.90E-03 

3.00E-Ol 8. 22E-06 1.93E-02 

4.00E-Ol 1.35E-05 4.15E-02 

5.00E-Ol 1.91E-05 7.15E-02 

6.00E-ol 2.49E-05 1.08E-Ol 

7.00E-Ol 3.07E-05 1.49E-Ol 

8.00E-Ol 3.66E-05 1.93E-Ol 

9.00E-Ol 4.23E-05 2.38E-Ol 

1.00E+00 4.80E-05 4.80E-05 2.85E-Ol 2.85E-ol 

2.00E+00 5.24E-05 1.00E-04 3.85E-Ol 6.68E-Ol 

3.00E+00 4.45E-05 1.44E-04 1.91E-Ol 8.55E-Ol 

4.00E+00 3.78E-05 1.81E-04 7.79E-02 9.28E-Ol 

5.00E+00 3.23E-05 2. 12E-04 2.97E-02 9.52E-Ol 

6.00E+00 2.76E-05 2.38E-04 1.11E-02 9.57E-Ol 

7.00E+00 2.37E-05 2.61E-04 4.08E-03 9.55E-Ol 

8.00E+00 2.04E-05 2.80E-04 1.50E-03 9.51E-Ol 

9.00E+00 1.77E-05 2.96E-04 5.48E-04 9.46E-Ol 

1.00E+Ol 1.54E-05 3.09E-04 2.00E-04 9.40E-Ol 

2.00E+Ol 5.40E-06 3. 74E-04 O.OOE+OO 8.86E-Ol 

3.00E+Ol 3.39E-06 3.92E-04 O.OOE+OO 8.34E-Ol 

4.00E+Ol 2.75E-06 3.98E-04 O.OOE+OO 7.85E-Ol 

5.00E+Ol 2.38E-06 3.99E-04 O.OOE+OO 7.39E-Ol 

6.00E+Ol 2.08E-06 3.97E-04 O.OOE+OO 6.96E-Ol 

7.00E+Ol 1.83E-06 3.93E-04 O.OOE+OO 6.55E-Ol 

8.00E+Ol 1.61E-06 3.87E-04 O.OOE+OO 6.17E-Ol 

9.00E+Ol 1.41E-06 3. 79E-04 O.OOE+OO 5.81E-Ol 

1.00E+02 1.24E-06 3.69E-04 O.OOE+OO 5.47E-Ol 

2.00E+02 3.39E-07 2.51E-04 O.OOE+OO 2.99E-Ol 

3.00E+02 9.28E-08 1.51E-04 O.OOE+OO 1.64E-Ol 

4.00E+02 2.54E-08 8.61E-05 O.OOE+OO 8.96E-02 

B-645 
INGESTION f l- 3.00E-ol STABLE 'l'UNGSTEB 184 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 1.OSE-Ol 8.82E-Ol 9.87E-Ol 

2.00E-Ol 1.68E-Ol 7. 77E-Ol 9.45E-Ol 

3.00E-Ol 1.7lE-Ol 7.l9E-Ol 8.89E-OI 

4.00E-OI 1.50E-OI 6.80E-Ol 8.30E-OI 

5.00E-Ol 1.2SE-Ol 6.47E-Ol 7.72E-OI 

6.00E-Ol I.OIE-OI 6.16E-Ol 7.17E-OI 

7.00E-OI 8.13E-02 S.83E-OI 6.65E-Ol 

8.00E-OI 6.S6E-02 S.SOE-Ol 6.l6E-OI 

9.00E-Ol S.34E-02 S.17E-Ol S.70E-Ol 

I.OOE+OO 4.39E-02 4.84E-Ol S.27E-Ol 

2.00E+OO 1.53E-02 2.l6E-OI 2.3lE-0l 

3.00E+OO 1.29E-02 8.S3E-02 9.82E-02 

4.00E+OO 1.2IE-02 3.23E-02 4.45E-02 

S.OOE+OO 1.16E-02 1.20E-02 2. 36E-02 

6.00E+OO 1.IIE-02 4.4SE-03 I.S6E-02 

·7.00E+OO I.07E-02 1.64E-03 1.23E-02 

8.00E+OO I.03E-02 6.0SE-04 1.09E-02 

9.00E+OO I.OOE-02 2.23E-04 1.02E-02 

I.OOE+OI 9.74E-03 8.l9E-OS 9.82E-03 

2.00E+OI B.22E-03 O.OOE+OO 8.22E-03 

3.00E+OI 7.69E-03 O.OOE+OO 7.69E-03 

4.00E+OI 7.4IE-03 O.OOE+OO 7.4IE-03 

S.OOE+OI 7.20E-03 O.OOE+OO 7.20E-03 

6.00E+OI 7.02E-03 O.OOE+OO 7.02E-03 

7.00E+OI 6.85E-03 O.OOE+OO 6.8SE-03 

8.00E+OI 6.69E-03 O.OOE+OO 6.69E-03 

9.00E+OI 6.S4E-03 O.OOE+OO 6.54E-03 

1.OOE+02 6.40E-03 O.OOE+OO 6.40E-03 

2.00E+02 S.32E-03 O.OOE+OO S.32E-03 

3.00E+02 4.64E-03 O.OOE+OO 4.64E-03 

4.00E+02 4.17E-03 O.OOE+OO 4.l7E-03 

S.OOE+02 3.8IE-03 O.OOE+OO 3.8lE-03 

6.00E+02 3.SIE-03 ·O.OOE+OO 3.SlE-03 

7.00E+02 3.26E-03 O.OOE+OO 3.26E-03 

8.00E+02 3.03E-03 O.OOE+OO 3.03E-03 

9.00E+02 2.B2E-03 O.OOE+OO 2.82E-03 

I.OOE+03 2.63E-03 O.OOE+OO 2.63E-03 

2.00E+03 1.3IE-03 O.OOE+OO 1.3IE-03 

3.00E+03 6.S7E-04 O.OOE+OO 6.S7E-04 

4.00E+03 3.2BE-04 O.OOE+OO 3.28E-04 

5.00E+03 1.64E-04 O.OOE+OO 1.64E-04 

6.00E+03 8.2IE-OS O.OOE+OO 8.2IE-OS 

7.00E+03 4.11E-OS O.OOE+OO 4.l1E-OS 

8.00E+03 2.05E-OS O.OOE+OO 2.0SE-OS 

9.00E+03 I.03E-OS O.OOE+OO I.03E-05 

I.OOE+04 S.14E-06 O.OOE+OO S.14E-06 

B-646 
INGESTION fI= 3.00E-ol STABLE TUNGSTEN 184 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

loOOE-OI 1.21E-02 S.BOE-04 

2.00E-OI 4.9SE-02 S.36E-03 

3.00E-OI 9.39E-02 1.69E-02 

4.00E-OI 1.3SE-OI 3.S2E-02 

S.OOE-OI 1.69E-OI S.90E-02 

6.00E-OI 1.96E-OI B.69E-02 

7.00E-OI 2.IBE-OI 1.IBE-OI 

B.OOE-OI 2.34E-OI I.SOE-Ol 

9.00E-OI 2.46E-OI l.B3E-Ol 

l.OOE+OO 2.S6E-OI 2.56E-OI 2.17E-Ol 2.17E-OI 

2.00E+OO 2.B7E-02 2.BSE-OI 2.6BE-Ol 4.B4E-OI 

3.00E+OO 2.4SE-03 2.B7E-Ol 1.30E-OI 6.15E-Ol 

4.00E+OO 7.23E-04 2.BBE-OI 5.30E-02 6.68E-OI 

S.OOE+OO S.44E-04 2.B8E-OI 2.03E-02 6.BBE-OI 

6.00E+OO 4.7IE-04 2.89E-Ol 7.S9E-03 6.96E-Ol 

7.00E+OO 4.12E-04 2.89E-Ol 2.8IE-03 6.98E-OI 

B.OOE+OO 3.62E-04 2.90E-OI I.04E-03 6.99E-OI 

9.00E+OO 3.IBE-04 2.90E-OI 3.82E-04 7.00E-OI 

I.OOE+OI 2.80E-04 2.90E-OI 1.4IE-04 7.00E-OI 

2.00E+Ol 8.S9E-OS 2.92E-Ol O.OOE+OO 7.00E-Ol 

3.00E+Ol 3.66E-OS 2.92E-O! O.OOE+OO 7.00E-Ol 

4.00E+OI 2.34E-OS 2.93E-Ol O.OOE+OO 7.00E-OI 

S.OOE+O! l.93E-OS 2.93E-O! O.OOE+OO 7.00E-O! 

6.00E+Ol !.7SE-OS 2.93E-Ol O.OOE+OO 7.00E-Ol 

7.00E+O! !.64E-OS 2.93E-Ol O.OOE+OO 7.00E-O! 

8.00E+Ol I.SSE-OS 2.93E-Ol O.OOE+OO 7.00E-O! 

9.00E+Ol l.46E-OS 2.93E-Ol O.OOE+OO 7.00E-O! 

!.OOE+02 !.38E-OS 2.94E-O! O.OOE+OO 7.00E-Ol 

2.00E+02 8.39E-06 2.9SE-Ol O.OOE+OO 7.00E-Ol 

3.00E+02 S.S7E-06 2.9SE-Ol O.OOE+OO 7.00E-O! 

4.00E+02 4.06E-06 2.96E-Ol O.OOE+OO 7.00E-Ol 

S.OOE+02 3.23E-06 2.96E-Ol O.OOE+OO 7.00E-O! 

6.00E+02 2.73E-06 2.96E-Ol O.OOE+OO 7.00E-Ol 

7.00E+02 2.40E-06 2.97E-O! O.OOE+OO 7.00E-Ol 

8.00E+02 2.17E-06 2.97E-OI O.OOE+OO 7.00E-O! -.. ·t.': 9.00E+02 1.99E-06 2.97E-OI O.OOE+OO 7.00E-Ol 

l.OOE+03 l.84E-06 2.97E-Ol O.OOE+OO 7.00E-Ol 

2.00E+03 9.lOE-07 2.99E-Ol O.OOE+OO 7.00E-O! 

3.00E+03 4.SSE-07 2.99E-Ol O.OOE+OO 7.00E-Ol 

4.00E+03 2.28E-07 3.00E-Ol O.OOE+OO 7.00E-Ol 

S.OOE+03 l.l4E-07 3.00E-Ol O.OOE+OO 7.00E-O! 

6.00E+03 S.69E-08 3.00E-Ol O.OOE+OO 7.00E-O! 

7.00E+03 2.8SE-08 3.00E-O! O.OOE+OO 7.00E-O! 

8.00E+03 !.42E-OB 3.00E-Ol O.OOE+OO 7.00E-O! 

B-647 
INGESTION fl= 8.00E-ol lIALFLlFE= 3.78E+OO DAYS BHENIUH 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 5.74E-OI 3.96E-OI 9.70E-OI 

2.00E-OI 7.09E-OI 2.14E-OI 9.23E-OI 

3.00E-OI 6.90E-OI I.B4E-OI B.74E-OI 

4.00E-OI 6.54E-OI l.72E-OI B.26E-Ol 

5.00E-OI 6.18E-OI 1.62E-Ol 7.79E-Ol 

6.00E-OI 5.B4E-Ol I.SIE-OI 7.34E-OI 

7.00E-Ol 5.52E-OI l.40E-OI 6.92E-OI 

8.00E-Ol 5.22E-OI 1.29E-OI 6.5IE-OI 

9.00E-OI 4.94E-OI 1.IBE-OI 6.12E-OI 

I.OOE+OO 4.67E-OI I.08E-OI 5. 76E-OI 

2.00E+OO 2.74E-OI 3.95E-02 3.l4E-Ol 

3.00E+OO 1.65E-OI 1.29E-02 1.78E-OI 

4.00E+OO I.02E-OI 4.06E-03 I.06E-Ol 

5.00E+OO 6.49E-02 l.26E-03 6.6IE-02 

6.00E+OO 4.22E-02 3.87E-04 4.26E-02 

7.00E+OO 2.8IE-02 l.19E-04 2.83E-02 

8.00E+OO l.92E-02 3. 64E-05 l.93E-02 

9.00E+OO 1.34E-02 1.12E-05 l.34E-02 

l.OOE+Ol 9.57E-03 3.42E-06 9.57E-03 

2.00E+Ol 6.20E-04 O.OOE+OO 6.20E-04 

3.00E+OI 6. 34E-05 O.OOE+OO 6. 34E-05 

4.00E+OI 7.18E-06 O.OOE+OO 7.18E-06 

5.00E+OI 8.32E-07 O.OOE+OO 8.32E-07 

6.00E+Ol 9.69E-08 O.OOE+OO 9.69E-08 

7.00E+Ol l.l3E-08 O.OOE+OO l.l3E-08 

:,: 

B-648 
DIGESTION f 1- 8.00£-01 BALFLIPE- 3.78£+00 DAYS IBENIUH 186 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.16E-02 3.97E-04 

2.00E-Ol 3.80E-02 2.83E-03 

3.00E-Ol 6.48E-02 7.44E-03 

4.00E-OI 8.97E-02 1.36E-02 

5.00E-OI 1.12E-Ol 2.07E-02 

6.00E-Ol 1.33E-Ol 2.83E-02 

7.00E-Ol 1.52E-Ol 3.6lE-02 

8.00E-Ol 1.69E-Ol 4.37E-02 

9.00E-Ol 1.8SE-Ol S.llE-02 

l.OOE+OO 1.99E-Ol 1.99E-Ol S.8lE-02 S.8lE-02 

2.00E+OO l.15E-Ol 2.80E-Ol 5.08E-02 9.9lE-02 

3.00E+OO 6.29E-02 2.96E-Ol 1.99E-02 1.02E-Ol 

4.00E+OO 3.54E-02 2.82E-Ol 6.69E-03 9.20E-02 

5.00E+OO 2.03E-02 2.55E-Ol 2.l2E-03 7.87E-02 

6.00E+OO 1.18E-02 2.24E-Ol 6.60E-04 6.62E-02 

7.00E+OO 6.98E-03 l.93E-Ol 2.03E-04 S.S3E-02 

8.00E+OO 4.20E-03 l.6SE-Ol 6.25E-05 4.6lE-02 

9.00E+OO 2.58E-03 1.40E-Ol 1.92E-05 3.84E-02 

1.OOE+Ol 1.6lE-03 1.18E-Ol 5.87E-06 3.20E-02 

2.00E+Ol 3. 75E,,:,,05 1.98E-02 O.OOE+OO S.llE-03 

3.00E+Ol 2.43E-06 3.20E-03 O.OOE+OO 8.l6E-04 

4.00E+Ol 2.40E-07 5.l5E-04 O.OOE+OO l.30E-04 

5.00E+Ol 2.69E-08 8.26E-OS O.OOE+OO 2.09E-05 

'. ,': .• ~ I " 

B-649 
INGESTION £1= 8.00E-Ol BALFLlFE= 1.83E+13 DAYS RHENIUM 187 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol S.8SE-OI 4.03E-Ol 9.88E-Ol 

2.00E-ol 7.36E-Ol 2.22E-Ol 9.S8E-OI 

3.00E-Ol 7.29E-OI 1.9SE-Ol 9.24E-Ol 

4.00E-Ol 7.03E-OI 1.86E-OI 8.89E-Ol 

S.OOE-OI 6.77E-Ol 1.77E-OI 8. S4E-O I 

6.00E-Ol 6.SIE-Ol l.68E-OI 8.20E-OI 

7.00E-OI 6.27E-Ol l.S9E-OI 7.86E-Ol 

8.00E-OI 6.04E-OI 1.49E-OI 7.S4E-Ol 

9.00E-OI 5.82E-OI l.40E-OI 7.22E-Ol 

1.OOE+OO 5.61E-OI 1.30E-OI 6.92E-Ol 

2.00E+OO 3.96E-Ol S.70E-02 4.53E-OI 

3.00E+OO . 2.87E-OI 2.24E-02 3.09E-Ol 

4.00E+OO 2.13E-Ol 8.46E-03 2.21E-OI 

5.00E+OO 1.62E-Ol 3.I5E-03 1. 65E-O1 

6.00-e+OO 1.27E-OI 1.16E-03 1.28E-OI 

7.00E+OO I.02E-OI 4.29E-04 I.02E-01 

8.00E+OO 8.33E-02 1.58E-04 8.35E-02 

9.00E+OO 6.99E-02 5.8IE-05 7.00E-02 

I.OOE+OI 5.99E-02 2.14E-OS 5.99E-02 

2.00E+OI 2.43E-02 O.OOE+OO 2.43E-02 

3.00E+OI 1.55E-02 O.OOE+OO 1.55E-02 

4.00E+OI 1.IOE-02 O.OOE+OO l.lOE-02 

5.00E+OI 7.98E-03 O.OOE+OO 7.98E-03 

6.00E+OI S.82E-03 O.OOE+OO 5.82E-03 

7.00E+OI 4. 24E-03 O.OOE+OO 4.24E-03 

8.00E+OI 3.10E-03 O.OOE+OO 3.10E-03 

9.00E+OI 2.26E-03 O.OOE+OO 2.26E-03 

l.OOE+02 1.6SE-03 O.OOE+OO 1.6SE-03 

2.00E+02 7.07E-OS O.OOE+OO 7.07E-OS 

3.00E+02 3.03E-06 O.OOE+OO 3.03E-06 

4.00E+02 I.30E-07 O.OOE+OO I.30E-07 

B-650 
INGESTION f 1

= 8.00E-Ol BALFLIFE= 1.83E+13 DAYS RHENIDM 187 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-Ol 1.19E-02 4.05E-04 

2.00E-OI 3.94E-02 2.93E-03 

3.00E-OI 6.85E-02 7.86E-03 

4.00E-Ol 9.65E-02 1.46E-02 

5.00E-OI 1.23E-OI 2.27E-02 

6.00E-Ol 1.49E-OI 3.l6E-02 

7.00E-Ol 1. 73E-OI 4.l0E-02 

8.00E-Ol 1.96E-Ol 5.07E-02 

9.00E-OI 2.18E-OI 6.03E-02 

1.OOE+OO 2.39E-Ol 2.39E-OI 6.98E-02 6.98E-02 

2.00E+OO l.66E-OI 4.04E-OI 7.33E-02 1.43E-Ol 

3.00E+OO I.09E-OI 5.13E-OI 3.46E-02 1.78E-Ol 

4.00E+OO 7.37E-02 5.87E-OI 1.39E-02 1.92E-Ol 

5.00E+OO 5.07E-02 6.38E-OI 5.3IE-03 l.97E-Ol 

6.00E+OO 3.55E-02 6.73E-OI I.98E-03 1.99E-Ol 

7.00E+OO 2.52E-02 6.98E-OI 7.35E-04 2.00E-OI 

8.00E+OO 1.82E-02 7.I7E-OI 2.7IE-04 2.00E-Ol 

9.00E+OO 1.34E-02 7.30E-OI 9.98E-05 2.00E-Ol 

I.OOE+Ol I.OlE-02 7.40E-Ol 3.67E-05 2.00E-OI 

2.00E+Ol 1.47E-03 7.76E-Ol O.OOE+OO 2.00E-OI 

3.00E+OI 5.96E-04 7.84E-OI O.OOE+OO 2.00E-Ol 

4.00E+Ol 3.67E-04 7.89E-OI O.OOE+OO 2.00E-OI 

5.00E+Ol 2.58E-04 7.92E-OI O.OOE+OO 2.00E-OI 

6.00E+OI I.87E-04 7.94E-OI O.OOE+OO 2.00E-Ol 

7.00E+Ol 1.36E-04 7.96E-Ol O.OOE+OO 2.00E-Ol 

8.00E+OI 9.9lE-05 7.97E-Ol O.OOE+OO 2.00E-Ol 

9.00E+Ol 7.23E-05 7.98E-OI O.OOE+OO 2.00E-OI 

1.00E+02 5.28E-05 7.98E-OI O.OOE+OO 2.00E-OI 

2.00E+02 2.26E-06 8.00E-Ol O.OOE+OO 2.00E-Ol 

3.00E+02 9.69E-08 8.00E-OI O.OOE+OO 2.00E-Ol 

B-651 
INGESTION £1'''' 1.00£-02 BALFLIFE- 7.40£+01 DAYS IR.IDIUH 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 2. 94E-03 9.9SE-OI 9.9SE-OI 

2.00E-Ol S.7SE-03 9.S6E-OI 9. 92E-OI 

3.00E-OI 7. 24E-03 9.70E-OI 9.77E-Ol 

4.00E-Ol 7. 93E-03 9. 46E-OI 9.S4E-Ol 

S.OOE-OI S'.20E-03 9.ISE-OI 9. 23E-Ol 

6.00E-OI S.27E-03 S.78E-OI S.S6E-OI 

7.00E-OI 8. 24E-03 8. 36E-OI 8. 44E-Ol 

S.OOE-OI 8.ISE-03 7. 92E-OI S.OOE-Ol 

9.00E-OI 8.10E-03 7.46E-Ol 7.S4E-OI 

I.OOE+OO 8.03E-03 6. 99E-OI 7.07E-Ol 

2.00E+OO 7.60E-03 3.14E-Ol 3. 22E-Ol 

3.00E+OO 7. 39E-03 I. 24E-Ol 1.31E-Ol 

4.00E+OO 7.l9E-03 4.6SE-02 S.37E-02 

S.OOE+OO 7.01E-03 1. 72E-02 2. 42E-02 

6.00E+OO 6.SSE-03 6.30E-03 1.3lE-02 

7.00E+OO 6. 69E-03 2.30E-03 S.99E-03 

S.OOE+OO 6.S4E-03 S.40E-04 7. 38E-03 

9.00E+OO 6. 39E-03 3.06E-04 6.70E-03 

i' I.OOE+Ol 6. 26E-03 1.12E-04 6. 37E-03 

2.00E+OI S.19E-03 O.OOE+OO S.19E-03 

3.00E+OI 4.4SE-03 O.OOE+OO '4.4SE-03 

4.00E+OI 3. 87E-03 O.OOE+OO 3. 87E-03 

S.OOE+OI 3. 39E-03 O.OOE+OO 3. 39E-03 

6.00E+OI 2. 97E-03 O.OOE+OO 2. 97E-03 

7.00E+Ol 2.61E-03 O.OOE+OO 2.6IE-03 

S.OOE+Ol 2.30E-03 O.OOE+OO 2.30E-03 

9.00E+OI 2.02E-03 O.OOE+OO 2.02E-03 

l.OOE+02 1.7SE-03 O.OOE+OO 1.7SE-03 

2.00E+02 4. 92E-04 O.OOE+OO 4. 92E-04 

3.00E+02 I. 36E-04 O.OOE+OO 1. 36E-04 

4.00E+02 3.7SE-OS O.OOE+OO 3.7SE-OS 

S.OOE+02 1.OSE-OS O.OOE+OO I.OSE-OS 

6.00E+02 2.9lE-06 O.OOE+OO 2.9IE-06 

7.00E+02 S.06E-07 O.OOE+OO 8.06E-07 

S.OOE+02 2. 23E-07 O.OOE+OO 2. 23E-07 

9.00E+02 6.19E-OS O.OOE+OO 6.19E-OS 

l.OOE+03 1.72E-OS O.OOE+OO 1.72E-OS 

B-6S2 
INGESTION f 1- l.ooE-02 BALFLIPE= 7. 40E+01 DAYS niDIUM 192 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-01 6. 59E-05 6.08E-04 

2.00E-01 2. 85E-04 5. 88E-03 

3.00E-01 5.71E-04 1. 92E-02 

4.00E-01 8. 55E-04 4. 13E-02 

5.00E-01 1. 11E-03 7.11E-02 

6.00E-01 1. 32E-03 1.07E-01 

7.00E-01 1.50E-03 1. 48E-01 

8.00E-01 1. 64E-03 1. 91E-01 

9.00E-01 1. 76E-03 2. 36E-01 

1.00E+00 1.85E-03 1. 85E-03 2. 82E-01 2. 82E-01 

2.00E+00 3. 78E-04 2. 21E-03 3.79E-01 6. 58E-01 

3.00E+00 1.47E-04 2. 34E-03 1. 87E-01 8. 39E-01 

4.00E+00 1. 22E-04 2. 44E-03 7.60E-02 9.07E-01 

5.00E-f00 1. 12E-04 2. 53E-03 2. 89E-02 9. 28E-01 

6.00E+00 1.03E-04 2. 61E-03 1.07E-02 9.30E-01. 

7.00E+00 9. 56E-05 2. 68E-03 3. 94E-03 9.25E-01 

8.00E+00 8. 85E-05 2. 74E-03 1. 44E-03 9. 18E-01 

9.00E+00 8. 19E-05 2.80E-03 5. 26E-04 9.lOE-01 

1.00E+01 7.60E-05 2. 85E-03 1.92E-04 9.01E-01 

2.00E+01 3. 88E-05 3.lOE-03 O.OOE+OO 8.21E-01 

3.00E+01 2. 34E-05 3.lOE-03 O.OOE+OO 7. 48E-01 

4.00E+01 1. 65E-05 3.01E-03 O.OOE+OO 6.81E-01 

5.00E+01 1. 29E-05 2. 88E-03 O.OOE+OO 6.20E-01 

6.00E+01 1.08E-05 2. 73E-03 O.OOE+OO 5. 64E-01 

7.00E+01 9. 23E-06 2. 58E-03 O.OOE+OO 5. 14E-01 

8.00E+01 8.03E-06 2. 43E-03 O.OOE+OO 4. 68E-01 

9.00E+01 7.03E-06 2. 29E-03 O.OOE+OO 4. 26E-01 

1.00E+02 6. 17E-06 2. 14E-03 O.OOE+OO 3. 88E-01 

2.00E+02 1. 71E-06 1.04E-03 O.OOE+oo 1. 52E-01 

3.00E+02 4. 74E-07 4. 66E-04 O.OOE+OO 5. 96E-02 

4.00E+02 1. 31E-07 1.98E-04 O.OOE+OO 2. 34E-02 

5.00E+02 3. 64E-08 S.21E-05 O.OOE+OO 9. 17E-03 

6.00E+02 1. OlE-OS 3. 34E-05 O.OOE+OO 3. 59E-03 

' .. 

:" . 

B-653 
INGESTION fl= 1.00E-02 STABLE IRIDIUM 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------~-------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 2. 94E-03 9.96E-Ol 9. 99E-Ol 

2.00E-Ol 5. 76E-03 9. 88E-Ol 9. 94E-Ol 

3.00E-Ol 7. 26E-03 9. 73E-Ol 9.80E-Ol 

4.00E-Ol 7. 96E-03 9.50E-Ol 9. 58E-Ol 

5.00E-Ol 8. 24E-03 9. 19E-Ol 9. 27E-Ol 

6.00E-Ol 8. 32E-03 8.83E-Ol 8.91E-Ol 

7.00E-Ol 8.30E-03 8.42E-Ol 8.50E-Ol 

8.00E-Ol 8. 24E-03 7.98E-Ol 8.06E-Ol 

9.00E-Ol 8.17E-03 7.52E-Ol 7.60E-Ol 

1.00E+00 8.lOE-03 7.06E-Ol 7. 14E-Ol 

2.00E+00 7. 75E-03 3.20E-Ol 3. 28E-Ol 

3.00E+00 7.60E-03 1.27E-Ol 1. 35E-Ol 

4.00E+00 7.47E-03 4.83E-02 5.58E-02 

5.00E+00 7. 35E-03 1.80E-02 2. 54E-02 

6.00E+00 7. 24E-03 6. 66E-03 1.39E-02 

7.00E+00 7.14E-03 2. 46E-03 9.60E-03 

8.00E+00 7.04E-03 9.05E-04 7. 95E-03 

9.00E+00 6. 95E-03 3. 33E-04 7.29E-03 

1.00E+Ol 6.87E-03 1.23E-04 6. 99E-03 

2.00E+Ol 6.26E-03 O.OOE+OO 6. 26E-03 

3.00E+Ol 5. 89E-03 O.OOE+OO 5. 89E-03 

4.00E+Ol 5. 63E-03 O.OOE+OO 5. 63E-03 

5.00E+Ol 5.41E-03 O.OOE+OO 5.41E-03 

6.00E+Ol 5. 21E-03 O.OOE+OO 5.21E-03 

7.00E+Ol 5.03E-03 O.OOE+OO 5.03E-03 

8.00E+Ol 4. 86E-03 O.OOE+QO 4. 86E-03 

9.00E+Ol 4. 69E-03 O.OOE+OO 4. 69E-03 

1.00E+02 4. 53E-03 O.OOE+OO 4. 53E-03 

2.00E+02 3.20E-03 O.OOE+OO 3.20E-03 

3.00E+02 2. 26E-03 O.OOE+OO 2. 26E-03 

4.00E+02 1.60E-03 O.OOE+OO 1.60E-03 

5.00E+02 1. 13E-03 O.OOE+OO 1. 13E-03 

6.00E+02 8.01E-04 O.OOE+OO 8.01E-04 

7.00E+02 5. 66E-04 O.OOE+OO 5. 66E-04 

8.00E+02 4.01E-04 O.OOE+OO 4.0lE-04 

9.00E+02 2. 83E-04 O.OOE+OO 2. 83E-04 

1.00E+03 2.00E-04 O.OOE+OO 2.00E-04 .' , .. 2.00E+03 6.'26E-06 O.OOE+OO 6. 26E-06 

3.00E+03 1. 96E-07 O.OOE+OO 1.96E-07 

B-654 
INGESTION f 1- 1.00£-02 STABLE IRIDIUM 193 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 6.60E-05 6.09E-04 

2.00E-Ol 2. 86E-04 5. 89E-03 

3.00E-Ol 5.72E-04 1. 93E-02 

4.00E-Ol 8. 58E-04 4.l4E-02 

5.00E-Ol 1.11E-03 7.l4E-02 

6.00E-Ol 1. 33E-03 1.08E-Ol 

7.00E-Ol 1.51E-03 1. 49E-Ol 

8.00E-Ol 1. 66E-03 1. 92E-Ol 

9.00E-Ol 1.77E-03 2. 38E-Ol 

1.OOE+OO 1. 87E-03 1. 87E-03 2. 84E-Ol 2. 84E-Ol 

2.00E+OO 3. 85E-04 2. 25E-03 3. 86E-Ol 6.70E-Ol 

3.00E+OO 1.5lE-04 2.40E-03 1. 93E-Ol 8. 63E-Ol 

4.00E+OO 1. 27E-04 2. 53E-03 7. 89E-02 9. 42E-Ol 

5.00E+OO 1.18E-04 2. 65E-03 3.03E-02 9. 72E-Ol 

6.00E+OO 1.09E-04 2. 76E-03 1.13E-02 9. 83E-Ol 

7.00E+OO 1.02E-04 2. 86E-03 4.2lE-03 9.88E-Ol 

8.00E+OO 9. 53E-05 2. 96E-03 1.55E-03 9. 89E-Ol 

9.00E+OO 8.9lE-05 3.05E-03 5. 72E-04 9.90E-Ol 

1.OOE+Ol 8. 35E-05 3.13E-03 2.l0E-04 9.90E-Ol 

2.00E+Ol 4. 68E-05 3. 74E-03 O.OOE+OO 9.90E-Ol 

3.00E+Ol 3.lOE-05 4.llE-03 O.OOE+OO 9.90E-Ol 

4.00E+Ol 2.40E-05 4.37E-03 O.OOE+OO 9.90E-Ol 

5.00E+Ol 2.06E-05 4. 59E-03 O.OOE+OO 9.90E-Ol 

6.00E+Ol 1. 89E-05 4. 79E-03 O.OOE+OO 9.90E-Ol 

7.00E+Ol 1. 78E-05 4. 97E-03 O.OOE+OO 9.90E-Ol 

8.00E+Ol 1.70E-05 5.14E-03 O.OOE+OO 9.90E-Ol 

9.00E+Ol 1. 63E-05 5.31E-03 O.OOE+OO· 9.90E-Ol 

1.OOE+02 1. 57E-05 5.47E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 1. llE-05 6.80E-03 O.OOE+OO 9.90E-Ol 

3.00E+02 7. 86E-06 7. 74E-03 O.OOE+OO 9.90E-Ol 

4.00E+02 5. 56E-06 8.40E-03 O.OOE+OO 9.90E-Ol 

5.00E+02 3. 93E-06 8. 87E-03 O.OOE+OO 9.90E-Ol 

6.00E+02 2. 78E-06 9.20E-03 O.OOE+OO 9.90E-Ol 

7.00E+02 1. 97E-06 9. 43E-03 O.OOE+OO 9.90E-Ol ., . '8.00E+02 1. 39E-06 9.60E-03 O.OOE+OO 9.90E-Ol 

9.00E+02 9. 83E-07 9.12E-03 O.OOE+OO 9.90E-Ol 

1.OOE+03 6.95E-07 9.80E-03 O.OOE+OO 9.90E-Ol 

2.00E+03 2.17E-08 9. 99E-03 O.OOE+OO 9.90E-Ol 

B-655 
INGESTION f 1'= 1.00£-02 STABLE PLATINUH 195 

TIME AFTER FRACTION OF INIT IAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 2. 94E-03 9. 96E-Ol 9. 99E-Ol 

2.00E-Ol 5. 73E-03 9. 88E-Ol 9. 94E-Ol 

3.00E-Ol 7. 19E-03 9.73E-Ol 9.80E-Ol 

4.00E-Ol 7.85E-03 9.50E-Ol 9. 58E-Ol 

5.00E-Ol 8.09E-03 9. 19E-Ol 9.27E-Ol 

6.00E-Ol 8. 12E-03 8. 83E-Ol 8.91E-Ol 

7.00E-Ol 8.05E-03 8. 42E-Ol 8.50E-Ol 

8.00E-Ol 7. 95E-03 7.98E-Ol 8.06E-01 

9.00E-Ol 7. 83E-03 7. 52E-Ol 7.60E-Ol 

1.00E+00 7.12E-03 7.06E-Ol 7. 13E-Ol 

2.00E+00 6. 92E-03 3.20E-Ol 3. 27E-Ol 

3.00E+00 6. 36E-03 1. 27E-Ol 1. 34E-Ol 

4.00E+00 5. 87E-03 4. 83E-02 5.42E-02 

5.00E+00 5.41E-03 1.80E-02 2. 34E-02 

6.00E+00 4. 99E-03 6. 66E-03 1. 17E-02 

7.00E+00 4. 61E-03 2. 46E-03 7.07E-03 

8.00E+00 4. 26E-03 9.05E-04 5. 16E-03 

9.00E+00 3. 94E-03 3. 33E-04 4.27E-03 

1.00E+Ol 3. 64E-03 1.23E-04 3. 76E-03 

2.00E+Ol 1.74E-03 O.OOE+OO 1. 74E-03 

3.00E+01 9. 36E-04 O.OOE+OO 9.36E-04 

4.00E+Ol 5.90E-04 O.OOE+OO 5.90E-04 

5.00E+01 4. 38E-04 ·O.OOE+OO 4. 38E-04 

6.00E+Ol 3. 68E-04 O.OOE+OO 3. 68E-04 

7.00E+Ol 3. 32E-04 O.OOE+OO 3. 32E-04 

8.00E+Ol 3. 11E-04 O.OOE+OO 3. 11E-04 

9.00E+Ol 2. 96E-04 O.OOE+OO 2. 96E-04 

1.00E+02 2. 84E-04 O.OOE+OO 2. 84E-04 

2.00E+02 2.00E-04 O.OOE+OO 2.00E-04 

3.00E+02 1.42E-04 O.OOE+OO 1. 42E-04 

4.00E+02 1.00E-04 O.OOE+OO 1.00E-04 

5.00E+02 7.08E-05 O.OOE+OO 7.08E-05 

6.00E+02 5. OlE-OS O.OOE+OO 5.01E-05 

7.00E+02 3. 54E-05 O.OOE+OO 3.54E-05 

8.00E+02 2.50E-05 O.OOE+OO 2.50E-05 

9.00E+02 1.77E-05 O.OOE+OO 1.77E-05 

.1.00E+03 1. 25E-05 O.OOE+OO 1. 25E-05 

2.00E+03 3. 91E-07 O.OOE+OO 3. 91E-07 

3. o OE+O 3 1.22E-08 O.OOE+OO 1.22E-08 

B-656 
INGESTION f 1- 1.00£-02 STABLE PLATINUM 195 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 7.22E-05 6.09E-04 

2.00E-OI 3.15E-04 5.B9E-03 

3.00E-Ol 6. 36E-04 l.93E-02 

4.00E-Ol 9. 63E-04 4.l4E-02 

5.00E-Ol l.26E-03 7.l4E-02 

6.00E-OI 1. 53E-03 I.OBE-Ol 

7.00E-0l I. 75E-03 1. 49E-Ol 

B.OOE-Ol 1. 95E-03 1.92E-Ol 

9.00E-Ol 2.llE-03 2.3BE-Ol 

l.OOE+OO 2. 25E-03 2. 25E-03 2.B4E-Ol 2. 84E-OI 

2.00E+OO B.29E-04 3.0BE-03 3.B6E-OI 6.70E-Ol 

3.00E+OO 5.57E-04 3. 64E-03 l.93E-Ol 8.63E-Ol 

4.00E+OO 4. 97E-04 4. 13E-03 7.B9E-02 9. 42E-OI 

5.00E+OO 4. 55E-04 4. 59E-03 3.03E-02 9.12E-Ol 

6.00E+OO 4.lBE-04 5.0lE-03 l.l3E-02 9.B3E-Ol 

7.00E+OO 3.B3E-04 5. 39E-03 4.21E-03 9.BBE-Ol 

B.OOE+OO 3. 52E-04 5. 74E-03 I.55E-03 9.B9E-Ol 

9.00E+OO 3. 22E-04 6.06E-03 5. 12E-04 9.90E-Ol 

1.OOE+Ol 2. 96E-04 6. 36E-03 2.lOE-04 9.90E-Ol 

2.00E+OI 1. 25E-04 B.26E-03 O.OOE+OO 9.90E-Ol 

3.00E+Ol 5. 33E-05 9.06E-03 O.OOE+OO 9.90E-Ol 

4.00E+Ol 2.3lE-05 9.4lE-03 O.OOE+OO 9.90E-OI 

5.00E+Ol 1.04E-05 9. 56E-03 O.OOE+OO 9.90E-Ol 

6.00E+Ol 5.00E-06 9. 63E-03 O.OOE+OO 9.90E-Ol 

7.00E+Ol 2. 72E-06 9.67E-03 O.OOE+OO 9.90E-Ol 

8.00E+Ol 1. 74E-06 9. 69E-03 O.OOE+OO 9.90E-Ol 

9.00E+OI I.3lE-06 9.70E-03 O.OOE+OO 9.90E-Ol 

l.OOE+02 1. IOE-06 9.12E-03 O.OOE+OO 9.90E-Ol 

2.00E+02 6. 95E-07 9. BOE-03 O.OOE+OO 9.90E-Ol 

3.00E+02 4.91E-07 9.B6E-03 O.OOE+OO 9.90E-Ol 

4.00E+02 3. 47E-07 9.90E-03 O.OOE+OO 9.90E-Ol 

5.00E+02 2. 46E-07 9. 93E-03 O.OOE+OO 9.90E-Ol 

6.00E+02 1. 74E-07 9. 95E-03 O.OOE+OO 9.90E-OI 

7.00E+02 1. 23E-07 9. 96E-03 O.OOE+OO 9.90E-OI 

B.OOE+02 B.69E-OB 9. 97E-03 O.OOE+OO 9.90E-Ol 

9.00E+02 6.14E-08 9.9BE-03 O.OOE+OO 9.90E-OI 

1.OOE+03 4. 35E-08 9. 99E-03 O.OOE+OO 9.90E-Ol 

B-657 
INGESTION f 1= 1.ooE-01 STABLE WLD197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 3.21E-02 9.67E-Ol 9. 99E-Ol 

2.00E-Ol 6.24E~02 9.30E-Ol 9.93E-Ol 

3.00E-01 7.82E-02 9.00E-Ol 9.78E-Ol 

4.00E-Ol 8. 54E-02 8.70E-Ol 9. 55E-Ol 

5.00E-Ol 8. 81E-02 8.37E-01 9.25E-Ol 

6.00E-01 8. 84E-02 8.01E-Ol 8.89E-Ol 

7.00E-Ol 8. 76E-02 7.62E-01 8.49E-Ol 

8.00E-Ol 8. 63E-02 7.20E-Ol 8.07E-Ol 

9.00E-Ol 8. 46E-02 6. 78E-Ol 7.63E-Ol 

1.00E+00 8.28E-02 6. 36E-Ol 7. 18E-Ol 

2.00E+00 6. 59E-02 2.87E-Ol 3. 52E-Ol 

3.00E+00 5.23E-02 1.14E-Ol 1.66E-Ol 

4.00E+00 4. 15E-02 4.32E-02 8. 47E-02 

5.00E+00 3.30E-02 1.61E-02 4.90E-02 

6.00E+00 2. 62E-02 5. 95E-03 3.21E-02 

7.00E+00 2.08E-02 2. 19E-03 2.30E-02 

8.00E+00 1. 65E-02 8.08E-04 1. 73E-02 

9.00E+00 1.31E-02 2. 97E-04 1. 34E-02 

1.00E+Ol 1.04E-02 1.09E-04 1.05E-02 

2.00E+01 1.03E-03 O.OOE+OO 1.03E-03 

3.00E+01 1.02E-04 O.OOE+OO 1.02E-04 

4.00E+Ol 1.02E-05 O.OOE+OO 1.02E-05 

5.00E+01 1.01E-06 O.OOE+OO 1.01E-06 

6.00E+Ol 1.00E-07 O.OOE+OO 1.00E-07 

B-658 
INGESTION £1= 1.00E-01 STABLE GOLD 197 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.10E-04 6.02E-04 

2.00E-Ol 1. 43E-03 5. 76E-03 

3.00E-Ol 3.08E-OJ l.87E-02 

4.00E-Ol 4. 98E-03 J.98E-02 

5.00E-Ol 6. 99E-03 6.80E-02 

6.00E-Ol 9.0JE-03 1.02E-Ol 

7.00E-Ol 1.llE-02 l.40E-Ol 

8.00E-Ol l.31E-02 1.80E-Ol 

9.00E-Ol l.51E-02 2. 22E-OI 

1.OOE+OO l.70E-02 1.70E-02 2. 65E-Ol 2. 65E-OI 

2.00E+OO I.71E-02· 3.4IE-02 3. 49E-Ol 6.13E-OI 

J.OOE+OO 1. 36E-02 4.77E-02 1. 73E-Ol 7. 86E-Ol 

4.00E+OO 1.08E-02 5.85E-02 7.06E-02 8.57E-OI 

5.00E+OO 8. 56E-03 6.70E-02 2.71E-02 8.84E-Ol 

6.00E+OO 6.80E-03 7. 38E-02 I.OIE-02 8.94E-0l I 7.00E+OO 5.40E-03 7. 92E-02 3. 76E-OJ 8. 98E-OI 

8.00E+OO 4. 28E-03 8. 35E-02 I. 39E-03 8. 99E-Ol 

9.00E+OO 3.40E-03 8. 69E-02 5.11E-04 9.00E-Ol 

I.OOE+Ol 2.70E-03 8. 96E-02 1.88E-04 9.00E-Ol 

2.00E+OI 2. 68E-04 9.90E-02 O.OOE+OO· 9.00E-Ol 

3.00E+OI 2. 66E-05 9. 99E-02 O.OOE+OO 9.00E-Ol 

4.00E+Ol 2. 64E-06 I.OOE-OI O.OOE+OO 9.00E-Ol 

5.00E+OI 2. 62E-07 1.OOE-0l O.OOE+OO 9.00E-OI 

6.00E+OI 2.60E-08 1.OOE-Ol O.OOE+OO 9.00E-Ol 

8-659 
INGESTION f 1= I.OOE+OO STABLE MERCUR.Y( Olle) 200 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 9.09E-OI 9.07E-02 9. 99E-OI 

2.00E-OI 9.90E-OI 8. 23E-03 9.99E-OI 

3.00E-0l 9. 97E-OI 7. 48E-04 9. 98E-OI 

4.00E-Ol 9. 97E-Ol 6. 86E-05 9. 97E-OI 

5.00E-OI 9. 96E-OI 7.02E-06 9. 96E-Ol 

6.00E-Ol 9. 95E-OI 1.38E-06 9. 95E-OI 

7.00E-OI 9. 95E-Ol S.30E-07 9. 95E-OI 

S.OOE-OI 9. 94E-Ol 7.35E-07 9. 94E-OI 

9.00E-OI 9. 93E-Ol 6.83E-07 9. 93E-Ol 

1.OOE+OO 9. 92E-Ol 6. 35E-07 9. 92E-OI 

2.00E+OO 9.S4E-Ol 2. 76E-07 9. 84E-OI 

3.00E+OO 9. 76E-Ol I.OSE-07 9.76E-OI 

4.00E+OO 9.6SE-OI 4.09E-08 9. 68E-OI 

5.00E+OO 9.60E-OI I. 52E-08 9.60E-OI 

6.00E+00 9. 52E-OI O.OOE+OO 9. 52E-OI 

7.00E+OO 9.44E-OI O.OOE+OO 9.44E-OI 

S.OOE+OO 9. 37E-Ol O.OOE+OO 9.37E-OI 

9.00E+OO 9. 29E-OI O.OOE+OO 9.29E-Ol 

I.OOE+OI 9.2IE-Ol O.OOE+OO 9.2IE-OI 

2.00E+OI 8.49E-OI O.OOE+OO S.49E-Ol 

3.00E+Ol 7.S3E-OI O.OOE+OO 7. 83E-Ol 

4.00E+OI 7.22E-OI O.OOE+OO 7. 22E-Ol 

5.00E+OI 6. 66E-OI O.OOE+OO 6. 66E-OI 

6.00E+Ol 6.15E-Ol O.OOE+OO 6.15E-OI 

7.00E+Ol 5.68E-Ol O.OOE+OO 5. 68E-OI 

8.00E+OI 5. 25E-Ol O.OOE+OO 5.25E-OI 

9.00E+OI 4. 85E-Ol O.OOE+OO 4. 85E-Ol 

1.OOE+02 4.49E-OI O.OOE+OO 4.49E-OI 

2.00E+02 2.17E-Ol O.OOE+OO 2.17E-OI 

3.00E+02 1.20E-01 O.OOE+OO 1.20E-01 

4.00E+02 7. 83E-02 O.OOE+OO 7. 83E-02 

5.00E+02 6.0SE-02 O.OOE+OO 6.08E-02 

6.00E+02 5. 32E-02 O.OOE+OO 5.32E-02 

7.00E+02 4. 98E-02 O.OOE+OO 4. 98E-02 

8.00E+02 4. 82E-02 O.OOE+OO 4. 82E-02 

9.00E+02 4. 74E-02 O.OOE+OO 4. 74E-02 

I.OOE+03 4. 68E-02 O.OOE+OO 4.6SE-02 

2.00E+03 4. 35E-02 O.OOE+OO 4. 35E-02 

3.00E+03 4.06E-02 O.OOE+OO 4.06E-02 

4.00E+03 3. 79E-02 O.OOE+OO 3. 79E-02 

5.00E+03 3.54E-02 O.OOE+OO 3. 54E-02 

7.00E+03 3.08E-02 O.OOE+OO 3.0SE-02 

S.OOE+03 2. 87E-02 O.OOE+OO 2. 87E-02 

9.00E+03 2. 68E-02 O.OOE+OO 2. 68E-02 

1.00E+04 2.50E-02 O.OOE+OO 2.50E-02 

2.00E+04 1.25E-02 O.OOE+OO I. 25E-02 

B-660 
INGESTION f l- 1.00£+00 STABLE MERCUllY(OJtG) 200 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 5. llE-04 4.l2E-09 

2.00E-Ol 1.3lE-03 2.1OE-08 

3.00E-Ol 2.l2E-03 4.92E-08 

4.00E-Ol 2. 95E-03 8. 57E-08 

5.00E-Ol 3. 77E-03 1. 28E-07 

6.00E-Ol 4. 59E-03 1. 73E-07 

7.00E-Ol 5.40E-03 2.2lE-07 

8.00E-Ol 6. 22E-03 2. 69E-07 

9.00E-Ol 7.04E-03 3.l7E-07 

1.OOE+OO 7. 86E-03 7. 86E-03 3. 65E-07 3. 65E-07 

2.00E+OO 8. 13E-03 1.60E-02 3.59E-07 7. 24E-07 

3.00E+OO 8.06E-03 2.40E-02 1. 68E-07 8. 92E-07 

4.00E+OO 7. 99E-03 3.20E-02 6.74E-08 9. 59E-07 

5.00E-fOO 7. 92E-03 4.00E-02 2. 57E-08 9.85E-07 

6.00E+OO 7. 85E-03 4. 78E-02 O.OOE+OO 9. 94E-07 

7.00E+OO 7. 79E-03 5. 56E-02 O.OOE+OO 9. 98E-07 

8.00E+OO 7.72E-03 6. 33E-02 O.OOE+OO 9.99E-07 

9.00E+OO 7. 65E-03 7.lOE-02 O.OOE+OO 1.OOE-06 

1. QOE+Ol 7. 59E-03 7. 86E-02 O.OOE+OO 1.OOE-06 

2.00E+Ol 6. 96E-03 1.5lE-Ol O.OOE+OO 1.OOE-06 

3.00E+Ol 6. 38E-03 2.l7E-0l O.OOE+OO 1.OOE-06 

4.00E+Ol 5. 85E-03 2. 78E-Ol O.OOE+OO 1.OOE-06 

5.00E+Ol 5. 37E-03 3.34E-Ol O.OOE+OO 1.OOE-06 

7.00E+Ol 4.5lE-03 4. 32E-Ol O.OOE+OO 1.OOE-06 

8.00E+Ol 4.)4E-03 4.75E-0l O.OOE+OO 1.OOE-06 

9.00E+Ol 3.80E-03 5.l5E-Ol O.OOE+OO 1.OOE-06 

1.OOE+02 3. 48E-03 5.5lE-Ol O.OOE+OO 1.OOE-06 

2.00E+02 1. 47E:"03 7.83E-Ol O.OOE+OO 1.OOE-06 

3.00E+02 6.l8E-04 8.80E-Ol O.OOE+OO 1.OOE-06 

4.00E+02 2. 62E-04 9. 22E-Ol O.OOE+OO 1.OOE-06 

5.00E+02 1.12E-04 9. 39E-Ol O.OOE+OO 1.OOE-06 

7.00E+02 2. 25E-05 9.50E-Ol O.OOE+OO 1.OOE-06 

8.00E+02 1.14E-05 9.52E-Ol O.OOE+OO 1.OOE-06 

9.00E+02 6. 65E-06 9. 53E-Ol O.OOE+OO 1.OOE-06 

1.OOE+03 4. 66E-06 9.53E-Ol O.OOE+OO 1.OOE-06 . -' /' ~ 2.00E+03 3.02E-06 9. 56E-Ol O.OOE+OO 1.OOE-06 

3.00E+03 2.8lE-06 9. 59E-Ol O.OOE+OO 1.OOE-06 

4.00E+03 2. 63E-06 9. 62E-Ol O.OOE+OO 1.OOE-06 

5.00E+03 2. 45E-06 9. 65E-Ol O.OOE+OO 1.OOE-06 

7.00E+03 2. 13E-06 9. 69E-Ol O.OOE'+OO 1.OOE-06 

8.00E+03 1. 99E-06 9. 71E-Ol O.OOE+OO 1.OOE-06 

9.00E+03 1. 86E-06 9. 73E-Ol O.OOE+OO 1.OOE-06 

1.OOE+04 1.73E-06 9.75E-0l O.OOE+OO 1.OOE-06 

.2.00E+04 8. 67E-07 9.87E-Ol O.OOE+OO 1.OOE-06 

B-661 
INGESTION fl= 1."00£+00 BALFLIFE= 1.38£+03 DAYS 'l'UALLIUK 204 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 9.05E-OI 9.07E-02 9. 96E-OI 

2.00E-OI 9.BIE-OI B.HE-03 9.B9E-Ol 

3.00E-OI 9.BIE-OI 7. 47E-04 9.B2E-0l 

4.00E-OI 9. 75E-OI 6.B6E-05 9. 75E-Ol 

5.00E-0l 9.6BE-OI 7.0IE-06 9.6BE-OI 

6.00E-OI 9. 62E-OI 1.3BE-06 9. 62E-OI 

7.00E-OI 9.55E-0l 8.29E-07 9. 55E-OI 

B.OOE-OI 9.48E-OI 7. 35E-07 9.4BE-OI 

9.00E-OI 9. 42E-OI 6.B3E-07 9.42E-0l 

I.OOE+OO 9.35E-OI 6. 35E-07 9. 35E-OI 

2.00E+OO B.72E-OI 2. 76E-07 B.72E-OI 

3.00E+OO B.13E-Ol I.OBE-07 B.13E-OI 

4.00E+OO 7. 59E-OI 4.0BE-OB 7.59E-Ol 

5.00E+OO 7.07E-OI I. 52E-OB 7.07E-0l 

6.00E+OO 6.60E-OI O.OOE+OO 6.60E-OI 

7.00E+OO 6.15E-OI O.OOE+OO 6. I 5E-O I 

8.00E+OO 5.74E-0l O.OOE+OO 5. 74E-OI 

9.00E+OO 5. 35E-OI O.OOE+OO 5. 35E-OI 

1.OOE+OI 4. 99E-OI O.OOE+OO 4. 99E-OI 

2.00E+OI 2.4BE-OI O.OOE+OO 2. 48E-Ol 

3.00E+OI I. 24E-OI O.OOE+OO I. 24R-OI 

4.00E+OI 6.15E-02 O.OOE+OO 6.15E-02 

5.00E+OI 3.06E-02 O.OOE+OO 3.06E-02 

6.00E+OI I. 52E-02 O.OOE+OO I. 52E-02 

7.00E+OI 7. 57E-03 O.OOE+OO 7. 57E-O) 

B.OOE+OI 3.77E-03 O.OOE+OO 3. 77E-03 

9.00E+Ol I.B7E-03 O.OOE+OO I:B7E-03 

I.OOE+02 9. 33E-04 O.OOE+OO 9. 33E-04 

2.00E+02 B.6BE-07 O.OOE+OO 8.6BE-07 

B-662 
INGESTION f l- I.OOE+OO BALFLIPE= 1.38E+03 DAYS 'l1IALLIUM 204 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUJlfULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 4. 29E-03 4. 12E-09 

2.00E-0l 1.09E-02 2.lOE-08 

3.00E-OI 1.77E-02 4. 92E-08 

4.00E-Ol 2. 45E-02 8.57E-08 

5.00E-Ol 3.l3E-02 1.28E-07 

6.00E-Ol 3. 79E-02 1. 73E-07 

7.00E-Ol 4. 46E-02 2.2lE-07 

8.00E-Ol 5.l2E-02 2. 69E-07 

9.00E-Ol 5.77E-02 3.l7E-07 

1.OOE+OO 6. 42E-02 6. 42E-02 3. 64E-07 3.64E-07 

2.00E+OO 6. 26E-02 1.27E-Ol 3. 59E-07 7. 23E-07 

3.00E+OO S.84E-02 1.85E-Ol 1. 68E-07 8.90E-07 

4.00E+OO 5. 44E-02 2.39E-0l 6.73E-08 9.S7E-07 

5.00E+OO 5.08E-02 2.90E-Ol 2. 56E-08 9. 82E-07 

6.00E+OO 4. 73E-02 3. 37E-Ol O.OOE+OO 9.91E-07 

7.00E+OO 4.4lE-02 3.8lE-Ol O.OOE+OO 9. 94E-07 

8.00E+OO 4.l2E-02 4. 22E-Ol O.OOE+OO 9.9SE-07 

9.00E+OO 3.84E-02 4.60E-OI O.OOE+OO 9.9SE-07 

1.00E+Ol 3.S8E-02 4. 96E-Ol O.OOE+OO 9.9SE-07 

2.00E+Ol 1. 78E-02 7.42E-Ol O.OOE+OO 9.90E-07 

3.00E+Ol 8.87E-03 8.62E-Ol O.OOE+OO 9.85E-07 

4.00E+Ol 4.4lE-03 9.l9E-OI O.OOE+OO 9.80E-07 

S.OOE+Ol 2. 19E-03 9.45E-Ol O.OOE+OO 9.7SE-07 

6.00E+Ol I.09E-03 9.SSE-OI O.OOE+OO 9.70E-07 

7.00E+OI S.43E-04 9. 58E-Ol O.OOE+OO 9. 65E-07 

8.00E+Ol 2.70E-04 9.S7E-Ol O.OOE+OO 9.61E-07 

9.00E+Ol 1.35E-04 9. S4E-Ol O.OOE+OO 9. 56E-07 

1.OOE+02 6.69E-OS 9.S0E-Ol O.OOE+OO 9.SlE-07 

2.00E+02 6.23E-08 9.04E-0l O.OOE+OO 9.04E-07 

B-663 
INGESTION f 1"'" 1.00£+00 STABLE THALLIUM 205 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 9.05E-Ol 9.07E-02 9. 96E-Ol 

2.00E-Ol 9.8lE-Ol 8.23E-03 9.89E-OI 

3.00E-Ol 9.82E-0l 7.4SE-04 9. 82E-Ol 

4.00E-Ol 9.75E-Ol 6.86E-05 9.75E-OI 

5.00E-Ol 9. 69E-Ol 7.02E-06 9.69E-Ol 

6.00E-Ol 9.62E-Ol 1.3SE-06 9.62E-Ol 

7.00E-Ol 9. 55E-Ol 8.30E-07 9. 55E-Ol 

8.00E-Ol 9.49E-Ol 7. 35E-07 9.49E-Ol 

9.00E-Ol 9.42E-Ol 6. 83E-07 9.42E-Ol 

1.00E+OO 9.36E-Ol 6.35E-07 9.36E-Ol 

2.00E+OO S.73E-Ol 2. 76E-07 8. 73E-OI 

3.00E+OO 8.l5E-Ol 1.08E-07 S.15E-Ol 

4.00E+OO 7.60E-Ol 4.09E-OS 7.60E-Ol 

5.00E+OO 7.09E-Ol l.52E-OS 7.09E-Ol 

6.00E+OO 6. 62E-Ol O.OOE+OO 6. 62E-Ol 

7.00E+OO 6.l7E-Ol O.OOE+OO 6.17E-Ol 

S.OOE+OO 5.76E-Ol O.OOE+OO 5. 76E-Ol 

9.00E+OO 5.3SE-Ol O.OOE+OO 5.38E-Ol 

1.OOE+Ol 5.02E-Ol O.OOE+OO 5.02E-Ol 

2.00E+Ol 2.5lE-Ol O.OOE+OO 2.5lE-Ol 

3.00E+Ol 1.25E-Ol O.OOE+OO 1.25E-Ol 

4.00E+Ol 6. 27E-02 O.OOE+OO 6.27E-02 

5.00E+Ol 3.l4E-02 O.OOE+OO 3.14E-02 

6.00E+Ol 1.57E-02 O.OOE+OO 1. 57E-02 

7.00E+Ol 7.S4E-03 O.OOE+OO 7.S4E-03 

8.00E+Ol 3. 92E-03 O.OOE+OO 3. 92E-03 

9.00E+Ol 1.96E-03 O.OOE+OO 1.96E-03 

1.OOE+02 9.8lE-04 O.OOE+OO 9.8lE-04 

2.00E+02 9. 59E-07 O.OOE+OO 9.59E-07 

B-664 
INGESTION f 1= 1.OOE+OO STABLE TBALLIUH 205 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR .ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 4. 29E-03 4.l2E-09 

2.00E-Ol 1.09E-02 2.1OE-08 

3.00E-Ol 1.77E-02 4. 92E-08 

4.00E-Ol 2. 45E-02 8. 57E-08 

5.00E-Ol 3. 13E-02 1. 28E-07 

6.00E-Ol 3. 79E-02 1. 73E-07 

7.00E-0l 4. 46E-02 2.2IE-07 

8.00E-Ol 5.l2E-02 2. 69E-07 

9.00E-Ol 5.77E-02 3.I7E-07 

1.OOE+OO 6. 43E-02 6.43E-02 3. 65E-07 3. 65E-07 

2.00E+OO 6. 27E-02 1.27E-0l 3. 59E-07 7. 24E-07 

3.00E+OO 5. 85E-02 1. 85E-Ol I.68E-07 8. 92E-07 

4.00E+OO 5. 45E-02 2.40E-Ol 6.74E-08 9. 59E-07 

5.00E+OO 5.09E-02 2.9lE-Ol 2. 57E-08 9. 85E-07 

6.00E+OO 4.75E-02 . 3. 38E-Ol O.OOE+OO 9. 94E-07 

7.00E+OO 4. 43E-02 3. 83E-Ol O.OOE+OO 9. 98E-07 

8.00E+OO 4.I3E-02 4. 24E-Ol O.OOE+OO 9. 99E-07 

9.00E+OO 3. 86E-02 4.62E-Ol O.OOE+OO 1.OOE-06 

l.OOE+OI 3.60E-02 4. 98E-Ol O.OOE+OO 1.OOE-06 

2.00E+Ol l.80E-02 7.49E-OI O.OOE+OO I.OOE-06 

3.00E+OI 9.00E-03 8. 75E-OI O.OOE+OO 1.OOE-06 

4.00E+Ol 4.50E-03 9.37E-OI O.OOE+OO I.OOE-06 

5.00E+OI 2. 25E-03 9. 69E-OI O.OOE+OO 1.OOE-06 

6.00E+OI 1. 13E-03 9. 84E-Ol O.OOE+OO 1.00E-06 

7.00E+OI 5. 63E-04 9. 92E-OI O.OOE+OO 1.00E-06 

8.00E+OI 2.8lE-04 9. 96E-Ol O.OOE+OO 1.00E-06 

9.00E+Ol I.41E-04 9.98E-0l O.OOE+OO l.OOE-06 

1.00E+02 7.04E-05 9. 99E-Ol O.OOE+OO I.OOE-06 

2.00E+02 6. 88E-08 I.OOE+OO O.OOE+OO I.OOE-06 

B-665 
INGESTION £1= 2.00E-01 STABLE LEAD 201 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 7.07E-02 9.29E-0l 9. 99E-Ol 

2.00E-Ol l.35E-OI 8. 59E-Ol 9. 94E-Ol 

3.00E-Ol l.68E-OI 8.l3E-OI 9.8lE-O! 

4.00E-O! 1.84E-Ol 7.77E-Ol 9.60E-Ol 

5.00E-Ol 1.'91E-Ol 7.43E-Ol 9.34E-Ol 

6.00E-Ol 1.93E-Ol 7.08E-Ol 9.02E-Ol 

7.00E-Ol 1.94E-Ol 6.72E-Ol 8.67E-OI 

8.00E-Ol I.94E-Ol 6.35E-Ol 8. 29E-OI 

9.00E-OI I.94E-Ol 5.97E-Ol 7.9lE-OI 

1.OOE+OO 1.93E-Ol 5.59E-OI 7. 52E-Ol 

2.00E+OO 1.86E-Ol 2.51E-Ol 4. 36E-Ol 

3.00E+OO 1.79E-Ol 9. 93E-02 2. 78E-Ol 

4.00E+OO 1. 72E-Ol 3. 76E!-02 2.l0E-OI 

5.00E+OO 1.66E-Ol 1.40E-02 1.80E-Ol 

6.00E+OO 1.60E-Ol 5.l9E-03 1.65E-Ol 

7.00E+OO 1.54E-Ol 1.91E-03 1. 56E-(ll 

8.00E+OO 1.49E-Ol 7.04E-04 1. 49E-Ol 

9.00E+OO 1.44E-Ol 2. 59E-04 1.44E-Ol 

1.OOE+Ol 1.39E-Ol 9.S4E-05 1. 39E-Ol 

2.00E+Ol 1.03E-OI O.OOE+OO 1.03E-Ol 

3.00E+Ol 8.25E-02 O.OOE+OO 8.2SE-02 

4.00E+Ol 7.03E-02 O.OOE+OO 7.03E-02 

5.00E+Ol 6.30E-02 O.OOE+OO 6.30E-02 

6.00E+Ol 5.84E-02 O.OOE+OO 5.84E-02 

7.00E+0l 5.53E-02 O.OOE+OO 5. 53E-02 

8.00E+Ol 5.31E-02 O.OOE+OO 5.31E-02 

9.00E+Ol 5.l5E-02 O.OOE+OO 5.lSE-02 

1.OOE+02 5.0lE-02 O.OOE+OO 5.0lE-02 

2.00E+02 4.l2E-02 O.OOE+OO 4.12E-02 

3.00E+02 3. 54E-02 O.OOE+OO 3. 54E-02 

4.00E+02 3.l3E-02 O.OOE+OO 3.13E-02 

5.00E+02 2.86E-02 O.OOE+OO 2. 86E-02 

6.00E+02 2. 66E-02 O.OOE+OO 2. 66E-02 

7.00E+02 2. 53E-02 O.OOE+OO 2. 53E-02 

8.00E+02 2. 43E-02 O.OOE+OO 2. 43E-02 

9.00E+02 2.36E-02 O.OOE+OO 2. 36E-02 

1.OOE+03 2.30E-02 O.OOE+OO 2.30E-02 

2.00E+03 2.07E-02 O.OOE+OO 2.07E-02 

3.00E+03 1.93E-02 O.OOE+OO 1. 93E-02 

4.00E+03 1.80E-02 O.OOE+OO 1.80E-02 

5.00E+03 1. 68E-02 O.OOE+OO 1. 68E-02 

7.00E+03 1.47E-02 O.OOE+OO 1.47E-02 

8.00E+03 1.37E-02 O.OOE+OO 1. 37E-02 

9.00E+03 1. 28E-02 O.OOE+OO 1. 28E-02 

1.OOE+04 '1.19E-02 O.OOE+OO 1.19E-02 

2.00E+04 5. 95E-03 O.OOE+OO 5. 95E-03 

B-666 
INGESTION £1= 2.00E-ol STABLE I...EAD207 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------------~-

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI I.2IE-04 S.92E-04 

2.00E-OI S.SIE-04 S.S8E-03 

3.00E-OI I.I7E-03 I.79E-02 

4.00E-OI I.89E-03 3. 76E-02 

S.OOE-OI 2.65E-03 6.38E-02 

6.00E-OI 3. 42E-03 9.48E-02 

7.00E-Ol 4.20E-03 l.29E-0l 

8.00E-OI 4.98E-03 I.66E-Ol 

9.00E-OI 5.76E-03 2.03E-OI 

I.OOE+OO 6.54E-03 6.54E-03 2.4IE-Ol 2.4IE-OI 

2.00E+OO 7. 53E-03 I.4IE-02 3.08E-OI S.49E-Ol 

3.00E+OO 7.12E-03 2. 12E-02 I.SIE-OI 7.OlE-Ol 

4.00E+OO 6. 73E-03 2.79E-02 6. 16E-02 7.62E.-OI 

S.OOE+OO 6. 36E-03 3.43E-02 2. 36E-02 7.86E-Ol 

6.00E+OO 6.0IE-03 4.03E-02 8. 84E-03 7.9SE-OI 

7.00E+OO S.68E-03 4.60E-02 3.28E-03 7.98E-Ol 

8.00E+OO S.37E-03 5.13E-02 1.21E-03 7.99E-OI 

9.00E+OO S.07E-03 S.64E-02 4.4SE-04 8.00E-OI 

1.00E+Ol 4.80E-03 6. 12E-02 I.64E-04 8.00E-OI 

2.00E+OI 2.75E-03 9.69E-02 O.OOE+OO 8.00E-0l 

3.00E+OI I.60E-03 I.18E-Ol O.OOE+OO 8.00g-01 

4.00E+Ol 9.SIE-04 1.30E-Ol O.OOE+OO 8.00E-Ol 

5.00E+Ol S.85E-04 1.37E-Ol O.OOE+OO 8.00E-Ol 

7.00E+Ol 2.60E-04 1. 45E-Ol O.OOE+OO 8.00E-Ol 

8.00E+0l 1. 92E-04 1.47E-Ol O.OOE+OO 8.00E-Ol 

9.00E+OI 1. 52E-04 1.49E-Ol O.OOE+OO 8.00E-Ol 

1.00E+02 1. 28E-04 I.50E-Ol O.OOE+OO 8.00E-Ol 

2.00E+02 7.00E-OS 1.59E-OI O.OOE+OO 8.00g-01 

3.00E+02 4.81E-OS 1.65E-0l O.OOE+OO 8.00E-Ol 

4.00E+02 3. 32E-05 1.69E-Ol O.OOE+OO 8.00E-Ol 

5.00E+02 2.31E-05 1.7iE-Ol O.OOE+OO 8.00E-OI 

7.00E+02 1.lSE-05 1.75E-Ol O.OOE+OO 8.00E-01 

8.00E+02 8. 34E-06 1.76E-Ol O.OOE+OO 8.00E-Ol 

9.00E+02 6. 16E-06 1.76E-Ol O.OOE+OO 8.00E-Ol 

1.00E+03 4.68E-06 1.17E-Ol O.OOE+OO 8.00E-Ol 

2.00E+03 1.50E-06 1.79E-Ol O.OOE+OO 8.00E-Ol 

3.00E+03 1.34E-06 1.8lE-OI O.OOE+OO 8.00E-OI 

4.00E+03 1.25E-06 1.82E-01 O.OOE+OO 8.00E-OI 

5.00E+03 1.17E-06 1.83E-Ol O.OOE+OO 8.00E-01 

7.00E+03 1.02E-06 I.8SE-Ol O.OOE+OO 8.00E-Ol 

8.00E+03 9.47E-07 1.86E-Ol O.OOE+OO 8.00E-01 

9.00E+03 8.84E-07 1.87E-OI O.OOE+OO 8.00E-OI 

I.OOE+04 8. 25E-07 1. 88E-OI O.OOE+OO 8.00E-01 

2.00E+04 4. 12E-07 1. 94E-Ol O.OOE+OO 8.00E-Ol 

B-667 
INGESTION £1= 1.00E-ol BALPLU'E- 1.38E+02 DAYS POLONIUM 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 3. 24E-02 9.67E-Ol 9.99E-Ol 

2.00E-Ol 6.37E-02 9.29E-Ol 9. 93E-Ol 

3.00E-Ol 8.IOE-02 8.99E-Ol 9.80E-Ol 

4.00E-Ol 8. 99E-02 8. 68E-Ol 9. 58E-Ol 

5.00E-Ol 9.44E-02 8.35E-Ol 9. 29E-Ol 

6.00E-Ol 9. 66E-02 7. 98E-Ol 8. 95E-Ol 

7.00E-Ol 9.76E-02 7.59E-Ol 8. 56E-01 

8.00E-Ol 9.81E-02 7.17E-Ol 8. 16E-Ol 

9.00E-Ol 9.82E-02 6.75E-01 7.73E-Ol 

1.00E+00 .9.82E-02 6.32E-Ol 7.31E-Ol 

2.00E+00 9. 65E-02 2.84E-Ol 3.80E-Ol 

3.00E+00 9.47E-02 1.12E-Ol 2.07E-Ol 

4.00E+00 9.30E-02 4. 23E-02 1.35E-01 

5.00E+00 9. 12E-02 1.57E-02 1.07E-Ol 

6.00E+00 8. 95E-02 5.77E-03 9.53E-02 

7.00E+00 8.78E-02 2. 12E-03 9.00E-02 

8.00E+00 8.62E-02 7.76E-04 8.70E-02 

9.00E+00 8.46E-02 2. 84E-04 8.49E-02 

1.00E+Ol 8.30E-02 1.04E-04 8.31E-02 

2.00E+Ol 6. 87E-02 O.OOE+OO 6. 87E-02 

3.00E+Ol 5.69E-02 O.OOE+OO 5.69E-02 

4.00E+Ol 4. 71E-02 O.OOE+OO 4. 71E-02 

5.00E+Ol 3.90E-02 O.OOE+OO 3.90E-02 

6.00E+Ol 3. 22E-02 O.OOE+OO 3. 22E-02 

7.00E+Ol 2.67E-02 O.OOE+OO 2.67E-02 

8.00E+Ol 2.21E-02 O.OOE+OO 2. 21E-02 

9.00E+Ol 1. 83E-02 O.OOE+oo 1.83E-02 

1.00E+02 1.51E-02 O.OOE+OO 1.51E-02 

2.00E+02 2. 28E-03 O.OOE+OO 2.28E-03 

3.00E+02 3. 45E-04 O.OOE+OO 3. 45E-04 

4.00E+02 5.20E-05 O.OOE+OO 5.20E-05 

5.00E+02 7.85E-06 O.OOE+OO 7. 85E-06 

6.00E+02 1.19E-06 O.OOE+OO 1. 19E-06 

7.00E+02 1.79E-07 O.OOE+OO 1.79E-07 

8.00E+02 2.70E-08 O.OOE+OO 2.70E-08 

.. , 

8-668 
INGESTION f 1== 1.00E-ol HALP'LIFE= 1.38E+02 DAYS POLONIUK 210 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1.SSE-06 6.lSE-04 

2.00E..,.Ol S.73E-06 5.S3E-03 

3.00E-Ol I.S9E-05 1.SSE-02 

4.00E-Ol 3.0SE-05 4.00E-02 

5.00E-0l 4. 37E-05 6.S2E-02 

6.00E-OI 5. 69E-05 I.02E-Ol 

7.00E-Ol 7.04E-05 1.40E-0l 

S.OOE-OI S.40E-05 1.SOE-OI 

9.00E-OI 9. 76E-05 2.22E-OI 

I.OOE+OO I.IIE-04 1.IIE-04 2. 64E-Ol 2. 64E-Ol 

2.00E+OO 1.35E-04 2. 46E-04 3. 47E-Ol 6.10E-OI 

3.00E+OO I. 33E-04 3.77E-04 1.71E-OI 7.7SE-0l 

4.00E+OO 1.30E-04 5.05E-04 7.04E-02 8. 44E-OI 

5.00E+OO 1.2SE-04 6.31E-04 2.76E-02 S.6SE-OI 

6.00EtOO I. 25E-04 7.53E-04 1.IOE-02 S.74E-OI 

7.00E+OO I. 23E-04 S.72E-04 4. 73E-03 S.75E-Ol 

S.OOE+OO 1.2IE-04 9.SSE-04 2. 42E-03 S.73E-OI 

9.00E+OO 1.ISE-04 1.IOE-03 I. 55E-03 8.70E-OI 

I.OOE+OI 1.16E-04 1.2IE-03 1.22E-03 S.67E-OI 

2.00E+OI 9.62E-05. 2.ISE-03 S.65E-04 S.34E-Ol 

3.00E+OI 7. 96E-05 2. 92E-03 7.16E-04 S.OIE-Ol 

4.00E+OI 6. 59E-05 3.4SE-03 5. 93E-04 7.6SE-OI 

5.00E+OI 5.45E-05 3.S9E-03 4.9IE-04 7.36E-OI 

6.00E+OI 4.5lE-05 4.ISE-03 4.06E-04 7.04E-Ol 

7.00E+Ol 3. 74E-05 4. 37E-03 3. 36E-04 6.73E-Ol 

S.()OE+Ol 3.09E-05 4.49E-03 2.7SE-04 6. 43E-Ol 

9.00E+Ol 2.56E-05 4. 54E-03 2.30E-04 6.l4E-Ol 

1.OOE+02 2.l2E-05 4. 55E-03 1.9lE-04 5.S6E-Ol 

2.00E+02 3.20E-06 3. 44E-03 2.SSE-05 3.6lE-0l 

3.00E+02 4. 83E-07 2.19E-03 4. 34E-06 2.20E-Ol 

4.00E+02 7.2SE-OS 1. 34E-03 6.56E-07 1. 33E-0l 

5.00E+02 1.lOE-08 8.l6E-04 9. 89E-OS S.09E-02 

. ~ ' .. :." ". 

B-669 
INGESTION £1= 2.00E-01 HALFLlFE- 1.14E+Ol DAYS RADIUM 223 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-Ol 4.20E-02 9. 23E-Ol 9. 65E-Ol 

2.00E-Ol 6.80E-02 8.48E-Ol 9.l6E-Ol 

3.00E-Ol 7. 82E-02 7. 98E-Ol 8. 76E-Ol 

4.00E-Ol 8.l0E-02 7.S8E-Ol 8. 39E-Ol 

S.OOE-Ol 8.0SE-02 7.2lE-Ol 8.0lE-Ol 

6.00E-Ol 7. 84E-02 6. 83E-Ol 7. 62E-Ol 

7.00E-Ol 7.S8E-02 6. 44E-Ol 7.20E-Ol 

8.00E-Ol 7.30E-02 6.0SE-OI 6. 78E-Ol 

9.00E-Ol 7.03E-02 S.6SE-Ol 6.3SE-Ol 

1.OOE+OO 6. 76E-02 S.26E-Ol S.94E-Ol 

2.00E+OO 4. 72E-02 2. 22E-Ol 2. 69E-Ol 

3.00E+OO 3. 49E-02 8. 28E-02 1.18E-Ol 

4.00E+OO 2.70E-02 2.9SE-02 S.6SE-02 

S.OOE+OO 2.l4E-02 1.04E-02 3.l8E-02 

6.00E+OO 1. 73E-02 3.6lE-03 2.09E-02 

7.00E+OO 1.4lE-02 1.2SE-03 1.S4E-02 

8.00E+OO 1.16E-02 4. 34E-04 1.2lE-02 

9.00E+OO 9. 68E-03 1.SOE-04 9. 83E-03 

1.OOE+Ol 8.l0E-03 5.20E-OS 8.lSE-03 

2.00E+Ol 1. 98E-03 O.OOE+OO 1. 98E-03 

3.00E+Ol 8.20E-04 O.OOE+OO 8.20E-04 

4.00E+Ol 4.I6E-04 - O .. OOE+OO 4.l6l!;-O4 

5.00E+Ol 2. 22E-04 O.OOE+OO 2. 22E-04 

6.00E+OI I.I9E-04 O.OOE+OO 1.19E-04 

7.00E+OI 6.4IE-OS O.OOE+OO 6.4IE-OS 

8.00E+Ol 3.4SE-05 O.OOE+OO ~.4SE-OS 

9.00E+Ol -1. 86E-OS O.OOE+OO I. 86E-OS 

I.OOE+02 1.OOE-OS O.OOE+OO I.OOE-OS 

2.00E+02 2.08E-08 O.OOE+OO 2.08E-08 

B-670 
DlGBSrIOR fl- 2.00Z-01 IlALPLIPE- 1.14£+01 DAYS RADIUM 223 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1. 42E-03 2. 76E-02 

2.00E-Ol 3. 31E-03 6. 84E-02 

3.00E-Ol 4. 41E-03 1.0lE-01 

4.00E-Ol 5.00E-03 1. 32E-Ol 

5.00E-Ol 5. 35E-03 1. 63E-Ol 

6.00E-Ol 5. 56E-03 1. 97E-Ol 

7.00E-Ol 5. 72E-03 2. 33E-Ol 

8.ooE-01 5. 84E-03 2. 69E-Ol 

9.00E-Ol 5. 94E-03 3.06E-Ol 

1.00E+00 6.03E-03 6.03E-03 3. 42E-Ol 3. 42E-Ol 

2.00E+00 8. 27E-04 6.50E-03 2. 89E-Ol 6.IOE-01 

3.00E+00 4. 73E-04 6. 59E-03 1. 35E-Ol 7.09E-Ol 

4.00E+00 2.95E-04 6.50E-03 5.40E-02 7. 22E-Ol 

5.00E+00 2.00E-04 6.31E-03 2. 12E-02 7.00E-Ol 

6.00E+00 1. 43E-04 6.09E-03 8. 86E-03 6. 68E-Ol 

7.00E+00 1.07E-04 5. 83E-03 4. 18E-03 6. 33E-Ol 

8.00£+00 8. 22E-05 5. 57E-03 2. 31E-03 5. 98E-Ol 

9.00E+00 6.41E-05 5. 31E-03 1. 48E-03 5. 64E-Ol 

1.00E+Ol 5.05E-05 5.05E-03 1.05E-03 5. 32E-Ol 

2.00E+Ol 5. 18E-06 2. 87E-03 9. 85E-05 2. 92E-Ol 

3.00E+Ol 5. 72E-07 1. 58E-03 1.09E-05 1.60E-Ol 

4.00E+Ol 7. 99E-08 8. 63E-04 1.52E-06 8. 71 E-O 2 

5.00E+Ol 1.95E-08 4.71E-04 3.70E-07 4. 75E-02 

B-671 
INGESTION fl= 2.00£-01 BALnU'£- 5.84£+05 DAYS BADIUM 226 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 4. 22E-02 9. 29E-Ol 9.llE-0l 

2.00E-Ol 6.SSE-02 8. 59E-0l 9.27E-Ol 

3.00E-Ol 7. 96E-02 8.13E-0l S.92E-Ol 

4.00E-Ol S.30E-02 7. 77E-Ol S.60E-Ol 

5.00E-Ol S.29E-02 7. 43E-Ol S.26E-Ol 

6.00E-Ol S.13E-02 7.0SE-Ol 7.90E-0l 

7.00E-Ol 7.9IE-02 6. 72E-Ol 7.5IE-0l 

S.OOE-Ol 7. 67E-02 6. 35E-ol 7.12E-OI 

9.00E-OI 7. 42E-02 5. 97E-Ol 6.llE-Ol 

I.OOE+OO 7.ISE-02 5. 59E-Ol 6.3lE-Ol 

2.00E+OO 5. 33E-02 2.5lE-Ol 3.04E-0l 

3.00E+OO 4.19E-02 9. 93E-02 1.4lE-Ol 

4.00E+OO 3. 44E-02 3. 76E-02 7.20E-02 

5.00E+OO 2.90E-02 1.40E-02 4.30E-02 

6.00E+OO 2. 49E-02 5.l9E-03 3.0lE-02 

7.00E+OO 2.16E-02 1.9lE-03 2. 35E-02 

S.OOE+OO 1.S9E-02 7.04E-04 1.96E-02 

9.00E+OO 1. 67E-02 2. 59E-04 1.70E-02 

I.OOE+OI 1. 49E-02 9. 54E-05 1.50E-02 

2.00E+Ol 6. 65E-03 O.OOE+OO 6. 65E-03 

3.00E+Ol 5.06E-03 O.OOE+OO 5.06E-03 

4.00E+Ol 4.7lE-03 O.OOE+OO 4.7lE-03 

5.00E+OI 4.60E-03 O.OOE+OO 4.60E-03 

6.00E+Ol 4. 53E-03 O.OOE+OO 4. 53E-03 

7.00E+Ol 4. 47E-03 O.OOE+OO 4. 47E-03 

S.OOE+Ol 4. 42E-03 O.OOE+OO 4. 42E-03 

9.00E+Ol 4. 36E-03 O.OOE+OO 4. 36E-03 

1.OOE+02 4.3lE-03 O.OOE+OO 4.3lE-03 

2.00E+02 3.S6E-03 O.OOE+OO 3.S6E-03 

3.00E+02 3.50E-03 O.OOE+OO 3.50E-03 

4.00E+02 3. 22E-03 O.OOE+OO 3. 22E-03 

5.00E+02 2. 99E-03 O.OOE+OO 2. 99E-03 

6.00E+02 2.SlE-03 O.OOE+OO 2.8lE-03 

7.00E+02 2. 65E-03 O.OOE+OO 2. 65E-03 

S.OOE+02 2. 52E-03 O.OOE+OO 2. 52E-03 

9.00E+02 2.4lE-03 O.OOE+OO 2.4IE-03 

1.OOE+03 2. 32E-03 O.OOE+OO 2. 32E-03 

2.00E+03 1.77E-03 O.OOE+OO 1. 77E-03 

3.00E+03 1. 46E-03 O.OOE+OO 1. 46E-03 

4.00E+03 I. 24E-03 O.OOE+OO I. 24E-03 

5.00E+03 1.OSE-03 O.OOE+OO I.OSE-03 

7.00E+03 S.55E-04 O.OOE+OO S.55E-04 

S.OOE+03 7.6SE-04 O.OOE+OO 7.6SE-04 

9.00E+03 6. 93E-04 O.OOE+OO 6. 93E-04 

I.OOE+04 6.2SE-04 O.OOE+OO 6. 28E-04 

2.00E+04 2. 56E-04 O.OOE+OO 2. 56E-04 

B-672 
DIGESTION f 1- 2.00£-01 IlALFLlI"E- 5.84£+05 DAYS RADIUM 226 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 1. 43E-03 2.7BE-02 

2.OOE-Ol 3. 35E-03 6. 93E-02 

3.00E-Ol 4. 49E-03 1.03E-Ol 

4.00E-Ol 5.13E-03 1. 35E-Ol 

5.00E-Ol 5.51E-03 1.6BE-Ol 

6.00E-ol 5.77E-03 2.04E-Ol 

7.00E-Ol 5. 97E-03 2. 43E-Ol 

B.OOE-Ol 6.l3E-03 2.B2E-Ol 

9.00E-Ol 6. 27E-03 3. 23E-Ol 

1.OOE+OO 6.40E-03 6.40E-03 3. 63E-Ol 3. 63E-Ol 

2.00E+OO 9. 34E-04 7.34E-03 3. 26E-Ol 6.B9E-Ol 

3.00E+OO 5. 67E-04 7.90E-03 1. 62E-Ol B.51E-Ol 

4.00E+OO 3.77E-04 B.2BE-03 6.BBE-02 9.20E-Ol 

5.00E+OO 2.70E-04 B.55E-03 2.BBE-02 9. 48E-Ol 

6.00E+OO 2.06E-04 B.76E-03 1.2BE-02 9.61E-Ol 

7.00E+OO 1. 64E-04 B.92E-03 6. 39E-03 9.6BE-Ol . 

B.OOE+OO 1. 34E-04 9.05E-03 3.75E-03 9.71E-Ol . 9.00E+OO 1.llE-04 9.16E-03 2. 55E-03 9. 74E-Ol 

1.OOE+Ol 9. 26E-05 9. 26E-03 1.92E-03 9. 76E-Ol 

2.OOE+Ol 1. 74E-05 9. 67E-03 3.31E-04 9.B4E-Ol 

3.00E+Ol 3. 53E-06 9. 75E-03 6.70E-05 9.B5E-Ol 

4.00E+Ol 9.03E-07 9. 76E-03 1. 72E-05 9.B5E-Ol 

5.00E+Ol 4.04E-07 9.77E-03 7. 67E-06 9. 86E-Ol 

6.00E+Ol 3.04E-07 9.77E-03 5.77E-06 9.B6E-Ol 

7.00E+Ol 2. 79E-07 9.7BE-03 5. 31E-06 9.B6E-Ol· 

B.OOE+Ol 2. 69E-07 9.7B.E-03 5.llE-06 9.B6E-Ol 

9.00E+Ol 2. 62E-07 9.7BE-03 4.9BE-06 9.B6E-Ol 

1.OOE+02 2. 55E-07 9.7BE-03 4.B5E-06 9.B6E-Ol 

2.00E+02 2.00E-07 9. BOE-03 3. BOE-06 9.B6E-Ol 

3.00E+02 1.5BE-07 9.B2E-03 3.01E-06 9.B6E-Ol 

4.00E+02 1.26E-07 9.B3E-03 2.40E-06 9.B6E-Ol 

5.00E+02 1.02E-07 9.B4E-03 1.9.4E-06 9.B7E-Ol 

6.00E+02 8.3BE-OB 9.B5E-03 1. 59E-06 9.B7E-Ol 

7.00E+02 6. 97E-OB 9.B6E-03 1. 32E-06 9.B7E-Ol 

B.OOE+02 5.BBE-OB 9.B6E-03 1.12E-06 9.B7E-Ol 

9.00E+02 5.03E-OB 9.B7E-03 9. 56E-07 9.B7E-Ol . ' . , 1.OOE+03 4. 37E-OB 9.B7E-03 B.30E-07 9.B7E-Ol 

2.00E+03 1.B9E-OB 9.B9E-03 3.60E-07 9.B6E-Ol 

3.00E+03 l.25E-08 9.B9E-03 2. 37E-07 9.B5E-Ol 

B-673 
INGESTION fl- 1.00£-03 BALFLIFE= 7.95£+03 DAYS ACTINIUK 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2.96E-04 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 5. 88E-04 9. 93E-Ol 9. 94E-Ol 

3.00E-Ol 7. 53E-04 9.80E-Ol 9.8lE-0l 

4.00E-Ol 8. 38E-04 9.57E-Ol 9. 58E-Ol 

5.00E-Ol 8.8lE-04 9. 27E-Ol 9.28E-Ol 

6.00E-Ol 9.0lE-04 8.9lE-Ol 8. 92E-Ol 

7.00E-OI 9.09E-04 8.50E-Ol 8.5IE-Ol 

8.00E-Ol 9.11E-04 8.05E-OI 8.06E-Ol 

9.00E-Ol 9.11E-04 7. 59E-Ol 7.60E-Ol 

1.OOE+OO 9.l0E-04 7.l3E-OI 7.l4E-Ol 

2.00E+OO 9.0IE-04 3. 23E-Ol 3. 24E-Ol 

3.00E+OO 9.00E-04 . 1. 29E-Ol 1. 29E-Ol 

4.00E+OO 9.00E-04 4. 88E-02 4. 97E-02 

5.00E+OO 9.00E-04 1. 82E-02 1.9IE-02 

6.00E+OO 9.00E-04 6. 73E-03 7. 63E-03 

7.00E+OO 9.00E-04 2. 48E-03 3. 38E-03 

8.00E+OO 8. 99E-04 9.l4E-04 1. 81E-03 

9.00E+OO 8. 99E-04 3. 36E-04 l.24E-03 

I.OOE+OI 8.99E-04 1. 24E;"'04 1.02E-03 

2.00E+Ol 8. 98E-04 O.OOE+OO 8. 98E-04 

3.00E+OI 8. 97E-04 O.OOE+OO 8. 97E-04 

4.00E+Ol 8. 96E-04 O.OOE+OO 8. 96E-04 

5.00E+Ol 8. 95E-04 O.OOE+OO 8.95E-04 

6.00E+Ol 8. 94E-04 O.OOE+OO 8. 94E-04 

7.00E+Ol 8. 93E-04 O.OOE+OO 8.93E-04 

8.00E+Ol 8. 92E-04 O.OOE+OO 8. 92E-04 

9.00E+OI 8.9lE-04 O.OOE+OO 8.9lE-04 

l.OOE+02 8.90E-04 O.OOE+OO 8.90E-04 

2.00E+02 8. 79E-04 O.OOE+OO 8.79E':'04 

3.00E+o2 8. 68E-04 O.OOE+OO 8. 68E-04 

4.00E+02 8. 58E-04 O.OOE+OO 8.58E-04 

5.00E+02 8. 48E-04 O.OOE+OO 8. 48E-04 

6.00E+02 8. 38E-04 O.OOE+OO 8. 38E-04 

7.00E+02 8. 28E-04 O.OOE+OO 8. 28E-04 

8.00E+02 8.l8E-04 O.OOE+OO 8.18E-:-04 

9.00E+02 8.08E-04 O.OOE+OO 8.08E-04 

1.OOE+03 7. 98E-04 O.OOE+OO 7. 98E-04 

2.00E+03 7.08E-04 O.OOE+OO 7.08E-04 

3.00E+03 6. 28E-04 O.OOE+OO 6.28E-04 

4.00E+03 5. 57E-04 O.OOE+OO 5. 57E-04 

5.00E+03 4. 94E-04 O.OOE+OO 4. 94E-04 

6.00E+03 4. 39E-04 O.OOE+OO 4. 39E-04 

7.00E+03 3.90E-04 O.OOE+OO 3.90E-04 

8.00E+03 3. 46E-04 O.OOE+OO 3. 46E-04 

9.00E+03 3.07E-04 O.OOE+OO 3.07E-04 

1.OOE+04 2. 73E-04 O.OOE+OO 2. 73E-04 

2.00E+04 8. 43E-05 O.OOE+OO 8. 43E-05 

B-674 
INGESTION fl-= 1.OOE-()3 BALFLIFE= 7.95E+03 DAYS ACTINIUM: 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC' NON-SYSTEMIC 

------------------ ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3.l6E-06 6.l0E-04· 

2.00E-Ol 1. 37E-05 5.90E-03 

3.00E-Ol 2.73E-05 1.93E-02 

4.00E-Ol 4.09E-05 4.l6E-02 

5.00E-Ol 5.30E-05 7.17E-02 

6.00E-Ol 6.3lE-05 1.OBE-Ol 

7.00E-Ol 7.l3E-05 1.49E-0l 

B.OOE-Ol 7.7BE-05 1. 94E-Ol 

9.00E-Ol B.29E-05 2.40E-Ol 

1.OOE+OO 8.6BE-05 8. 68E-05 2.B6E-Ol 2.B6E-Ol 

2.00E+OO 1.20E-05 9.B9E-OS 3. B9E-Ol 6. 76E-Ol 

3.00E+OO 7. 99E-07 9. 97E-05 1.9SE-Ol 8.70E-Ol 

4.00E+OO 7.8lE-OB 9. 97E-OS 7.97E-02 9.S0E-Ol 

5.00E+OO 3. 29E-08 9. 97E-OS 3.06E-02 9. BOE-Ol 

6.00E+OO 3.0lE-08 9. 98E-05 1.lSE-02 9.92E-0l 

7.00E+OO 2. 99E-OB 9. 98E-05 4.2SE-03 9. 96E-Ol 

B.OOE+OO 2. 99E-OB 9. 98E-OS 1. S7E-03 9. 97E-Ol 

9.00E+OO 2. 99E-OB 9.9BE-05 5.7BE-04 9. 98E-Ol 

1.OOE+Ol 2. 99E-OB 9. 99E-05 2.l3E-04 9.98E-0l 

2.00E+Ol 2.9BE-08 1.OOE-04 O.OOE+OO 9.97E-Ol 

3.00E+Ol 2. 98E-OB 1.OOE-04 O.OOE+OO 9. 96E-Ol 

4.00E+Ol 2. 98E-OB 1.OOE-04 O.OOE+OO 9. 96E-Ol 

5.00E+Ol 2. 97E-OB 1.OlE-04 O.OOE+OO 9.9SE-Ol 

6.00E+Ol 2. 97E-OB 1.OlE-04 O.OOE+OO 9. 94E-Ol 

7.00E+Ol 2. 96E-08 1.OIE-04 O.OOE+OO 9. 93E-Ol 

B.OOE+OI 2. 96E-OB 1.OlE-04 O.OOE+OO 9. 92E-Ol 

9.00E+Ol 2. 96E-OB 1.02E-04 O.OOE+OO 9.9IE-OI 

1 .. OOE+02 2.9SE-08 1.02E-04 O.OOE+OO 9.90E-Ol 

2.00E+02 2. 92E-OB 1.04E-04 O.OOE+OO 9.B2E-OI 

3.00E+02 2. 88E-08 1.06E-04 O.OOE+OO 9. 73E-Ol 

4.00E+02 2. 84E-08 1.08E-04 O.OOE+OO 9. 65E-Ol 

S.OOE+02 2.8lE-08 l.lOE-04 O.OOE+OO 9. 56E-Ol 

6.00E+02 2.77E-08 1.UE-04 O.OOE+OO 9.4BE-Ol 

7.00E+02 2. 74E-08 1.13E-04 O.OOE+OO 9.40E-Ol 

8.00E+02 2.70E-08 1.lSE-04 O.OOE+OO 9. 32E-OI 

9.00E+02 2. 67E-OB 1.17E-04 O.OOE+OO 9.24E-Ol 

1.OOE+03 2. 64E-08 1.18E-04 O.OOE+OO 9.l6E-Ol 

2.00E+03 2. 32E-08 1. 32E-04 O.OOE+OO 8.39E-OI 

3.00E+03 2.0SE-08 1. 42E-04 O.OOE+OO 7.69E-Ol 

4.00E+03 1.8lE-OB 1. 48E-04 O.OOE+OO 7.0SE-Ol 

S.OOE+03 1.S9E-08 1.S2E-04 O.OOE+OO 6.46E-Ol 

6.00E+03 1.40E-08 1.S4E-04 O.OOE+OO 5. 92E-Ol 

7.00E+03 I. 24E-08 I. 54E-04 O.OOE+OO S.43E-OI 

8.00E+03 1.09E-OB 1. 52E-04 O.OOE+OO 4. 97E-OI 

B-67S 
INGESTION f1- 2.00E-04 BALl'LIFE- 1.87E+01 DAYS mOB.IDH 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 5. 92E-05 9. 96E-Ol 9. 96E-Ol 

2.00E-Ol 1. 18E-04 9.87E-Ol 9.87E-Ol 

3.00E-Ol 1.51E-04 9.70E-Ol 9.70E-Ol 

4.00E-Ol 1. 68E-04 9. 44E-Ol 9. 44E-Ol 

5.00E-Ol 1.77E-04 9. lIE-01 9. llE-OI 

6.00E-Ol 1.80E-04 8. 72E-Ol 8. 72E-Ol 

7.00E-Ol 1. 82E-04 8. 29E-Ol 8. 29E-01 

8.00E-Ol 1. 81E-04 7.83E-Ol 7. 83E-Ol 

9.00E-Ol 1. 81E-04 7. 35E-Ol 7. 35E-01 

1.00E+00 1. 79E-04 6. 87E-Ol 6. 88E-Ol 

2.00E+00 1. 69E-04 3.00E-Ol 3.01E-Ol 

3.00E+00 1. 61E-04 1. 15E-Ol 1. 15E-Ol 

4.00E+00 1.55E-04 4. 22E-02 4. 23E-02 

5.00E+00 1. 49E-04 1. 51E-02 1. 53E-02 

6.00E+00 1. 44E-04 5.40E-03 5. 54E-03 

7.00E+00 1. 39E-04 1. 92E-03 2.06E-03 

8.00E+00 1.34E-04 6. 81E-04 8. 14E-04 

9.00E+00 1. 29E-04 2. 41E-04 3.70E-04 

·1 1.00E+Ol 1. 24E-04 8. 56E-05 2.10E-04 

2.00E+Ol 8. 53E-05 O.OOE+OO 8. 53E-05 

3.00E+Ol 5. 88E-05 O.OOE+oo 5. 88E-05 

4.00E+Ol 4.05E-05 O.OOE+OO 4.05E-05 

5.00E+Ol 2. 79E-05 O.OOE+OO 2. 79E-05 

6.00E+Ol 1. 92E-05 O.OOE+OO 1. 92E-05 

7.00E+Ol 1. 32E-05 O.OOE+OO ·1. 32E-05 

8.00E+Ol 9.10E-06 O.OOE+OO 9.10E-06 

9.00E+Ol 6. 27E-06 O.OOE+oo 6. 27E-06 

1.00E+02 4. 32E-06 O.OOE+OO 4. 32E-06 

2.00E+02 1.04E-07 O.OOE+oo 1.04E-07 

B-676 
INGESTIOR fl- 2.00E-04 IlALl"LIPE- 1.87E+Ol DAYS moll.IUH 227 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

----------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

I.OOE-OI 3. 29E-07 6.07E-04 

2.00E-ol 1.4SE-06 5.S6E-03 

3.00E-0l 3.0SE-06 1.9IE-02 

4.00E-OI 4.SIE-06 4.lOE-02 

5.00E-Ol 6. 49E-06 7.05E-02 

6.00E-Ol S.04E-06 1.06E-Ol 

7.00E-OI 9. 44E-06 1. 46E-0l 

S.OOE-OI I.07E-05 I.SSE-OI 

9.00E-OI 1.17E-05 2. 32E-OI 

I.OOE+OO 1. 27E-05 1.27E-05 2. 76E-OI 2. 76E-OI 

2.00E+OO 4.S4E-06 1.71E-05 3.62E-0l 6.2SE-Ol 

3.00E+OO 1.20E-06 1. 76E-05 1. 74E-OI 7.S0E-OI 

4.00E+OO 3. 24E-07 1.73E-05 6.SSE-02 S.20E-OI 

5.00E+OO 1.IOE-07 1.6SE-05 2. 55E-02 S.16E-OI 

6.00E+OO 5. 75E-OS 1. 62E-05 9.19E-03 7. 95E-OI 

7.00E+OO 4. 36E-OS 1. 57E-05 3.2SE-03 7.70E':"OI 

S.OOE+OO 3. 92E-OS 1. 52E-05 1.17E-03 7.43E-Ol 

9.00E+OO 3.71E-OS 1. 47E-05 4.15E-04 7. 1 6E-O 1 

I.OOF+OI 3. 55E-OS 1. 42E-05 1.47E-04 6.90E-Ol 

2.00E+Ol 2. 43E-OS 1.00E-05 O.OOE+OO 4. 77E-Ol 

3.00E+OI 1. 67E-OS 7.09E-06 O.OOE+OO 3. 29E-OI 

4.00E+OI 1.14E-OS 5.01E-06 O.OOE+OO 2. 27E-Ol 

B-617 
INGESTION f1 ... 2.008-04 JlALFLIn- 2.818+07 MYS 'lU.OR.IUII 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ----------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 5. 94E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 1. 19E-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 1. 53E-04 9.80E-Ol 9.81E-Ol 

4.00E-Ol 1.71E-04 9. 58E-Ol 9. 58E-Ol 

5.00E-Ol 1~80E-04 9. 28E-Ol 9.28E-Ol 

6.00E-Ol 1. 84E-04 8.92E-Ol 8.92E-Ol 

7.00E-0l 1.86E-0,4 8.50E-Ol 8.51E-Ol 

8.00E-Ol 1.87E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 1.87E-04 7.60E-Ol 7.60E-Ol 

1.00E+OO 1. 86E-04 7. 13E-Ol 7. 13E-Ol 

2.00E+OO 1. 82E-04 3. 24E-Ol 3. 24E-Ol 

3.00E+OO 1.80E-04 1. 29E-Ol 1. 29E-Ol 

4.00E+OO 1.80E-04 4. 89E-02 4. 91E-02 

5.00E+OO 1.80E-04 1. 82E-02 1. 84E-02 

6.00E+OO 1.80E-04 6. 74E-03 6. 92E-03 

7.00E+OO 1.80E-04 2. 49E-03 2. 67E-03 

8.00E+OO 1.80E-04 9.l6E-04 1.iOE-03 

9.00E+OO 1.80E-04 3. 37E-04 5. 17E-04 

1.00E+Ol 1. 79E-04 1. 24E-04 3.03E-04 

2.00E+Ol 1. 79E-04 O.OOE+OO 1. 79E-04 

3.00E+Ol 1. 78E-04 O.OOE+OO 1. 78E-04 

4.00E+Ol 1. 78E-04 O.OOE+OO 1. 78E-U4 

5.00E+Ol 1.77E-04 O.OOE+OO 1.77E-04 

6.00E+Ol 1.77E-04 O.OOE+OO 1.77E-04-

7.00E+Ol 1. 76E-04 O.OOE+OO 1.76E-04 

8.00E+Ol 1. 76E-04 O.OOE+OO 1,76E-04 

9.00E+Ol 1. 76E-04 O.OOE+OO 1. 16E-04 

1.00E+02 1. 75E-04 O.OOE+OO 1. 75E-04 

2.00E+02 1.70E-04 O.OOE+OO 1.70E-04 

3.00E+02 1. 66E-04 O.OOE+OO 1. 66E-04 

4.00E+02 1. 62E-04 O.OOE+OO 1. 62E-04 

5.00E+02 1. 58E-04 O.OOE+OO 1. 58E-04 

6.00E+02 1. 55E-04 O.OOE+OO 1.55E-04 

7.00E+02 1. 52E-04 O.OOE+OO 1. 52E-04 

8.00E+02 1.49E-04 O.OOE+OO 1. 49E-04 

9.00E+02 1. 46E-04 O.OOE+OO 1. 46E-04 

1.00E+03 1. 43E-04 O.OOE+OO 1.43E-04 

2.00E+03 1. 23E-04 O.OOE+OO 1.23E-04 

3.00E+03 1.lOE-04 O.OOE+OO l.l0E-04 

4.00E+03 9. 98E-05 O.OOE+OO 9. 98E-05 

5.00E+03 9.l1E-05 O.OOE+OO 9.11E-05 

6.00E+03 8.33E-05 O.OOE+OO B.33E-05 

7.00E+03 7. 64E-05 O.OOE+OO 7. 64E-05 

8.00E+03 7.00E-05 O.OOE+OO 7.00E-05 

9.00E+03 6. 42E-05 O.OOE+OO 1j.42E-05 

1.OOE+04 5. 89E-05 O.OOE+OO 5. 89E-05 

2.00E+04 2. 47E-05 O.OOE+OO 2. 47E-05 

B-618 
INGESTION . £1= 2.00E-04 BALFLIFE- 2.81E+07 DAYS 'l'BOllIUK 230 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3.30E-07 6.10E-04 

2.00E-Ol 1.49E-06 S.90E-03 

3.00E-Ol 3.l2E-06 l.94E-02 

4.00E-Ol 4. 88E-06 4.16E-02 

S.OOE-Ol 6.6IE-06 7.lBE-02 

6.00E-Ol B.22E-06 I.OBE-OI 

7.00E-Ol 9.6BE-06 l.49E-OI 

B.OOE-Ol 1.lOE-OS 1. 94E-Ol 

9.00E-Ol 1.2lE-OS 2.40E-Ol 

1.OOE+OO 1.32E-OS 1.32E-OS 2.B7E-Ol 2.B7E-Ol 

2.00E+OO S.2lE-06 1.B4E-OS 3.90E-Ol 6.76E-Ol 

3.00E+OO 1.3SE-06 1.97E-OS 1.9SE-Ol B.71E-Ol 

4.00E+OO 3.7SE-07 2. OlE-OS 7.9BE-02 9.SlE-Ol 

S.OOE+OO 1.33E-07 2.02E-OS 3.07E-02 9.B2E-Ol 

6.00E+OO 7.lBE-OB 2.03E-OS 1.lSE-02, 9. 93E-Ol 

7.00E+OO S.6SE-OB 2.03E-OS 4. 26E .... 03 9.97E-Ol 

B.OOE+OO S.27E-OB 2.04E-OS 1.S7E-03 9. 99E-Ol 

9.00E+OO S.17E-OB 2.0SE-OS, S.79E-04 9. 99E-Ol 

1.OOE+Ol S.14E-OB 2.0SE-OS 2.13E-04 1.OOE+OO 

2.00E+Ol S.lOE-08 2.lOE-OS 1.02E-OB 1.OOE+OO 

3.00E+Ol S.06E-OB 2.lSE-OS O.OOE+OO 1.OOE+OO 

4.00E+Ol S.02E-08 2.20E-OS O.OOE+OO 1.OOE+OO 

S.OOE+Ol 4.9BE-OB 2.2SE-OS O.OOE+OO l.OOE+OO 

6.00E+Ol 4. 94E-08 2.30E-OS O.OOE+OO 1.OOE+OO 

7.00E+Ol 4.90E-08 2.3SE-OS O.OOE+OO 1.OOE+OO 

B.OOE+Ol 4.B7E-OB 2.40E-OS O.OOE+OO 1.OOE+OO 

9.00E+Ol 4.B3E-OB 2.4SE-OS O.OOE+OO 1.OOE+OO 

1.OOE+02 4. 79E-OB 2.S0E-OS O.OOE+OO 1.OOE+OO 

2.00E+02 4. 44E-OB 2. 96E-05 O.OOE+OO 1.OOE+OO 

3.00E+02 4.13E-OB 3. 39E-05 O.OOE+OO 1.OOE+OO 

4.00E+02 3. 84E-08 3.7BE-05 O.OOE+OO 1.OOE+OO 

5.00E+02 3.5BE-08 4.1SE-OS O.OOE+OO 1.OOE+OO 

6.00E+02 3. 34E-OB 4.S0E-OS O.OOE+OO 1.OOE+OO 

7.00E+02 3.l2E-08 4.B2E-OS O.OOE+OO 1.OOE+OO 

B.OOE+02 2. 93E-OB 5.12E-05 O.OOE+OO 1.OOE+OO 

9.00E+02 2.7SE-OB S.4lE-05 O.OOE+OO 1.OOE+OO 

1.OOE+03 2. 58E-OB 5. 67E-05 O.OOE+OO 1.OOE+OO 

2.00E+03 1.S7E-OB 7. 67E-05 O.OOE+OO 1.OOE+OO 

3.00E+03 1.14E-08 9.00E-05 O.OOE+OO 1.OOE+OO 

B-679 
INGESTION fl= 2.00&-04 BALFLIPE= 5.13&+12 DAYS THORIUM 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 5. 94E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol l.19E-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 1.53E-04 9. BOE-Ol 9.BlE-Ol 

4.00E-Ol 1.71E-04 9.5BE-Ol 9.5BE-Ol 

5.00E-Ol 1.80E-04 9.28E-Ol 9. 28E-Ol 

6.00E-Ol I.B4E-04 B.92E-Ol B.92E-Ol 

7.00E-Ol 1. 86E-04 B.50E-Ol B.SIE-Ol 

8.00E-Ol l.87E-04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 1.87E-04 7.60E-Ol 7.60E-Ol 

1.OOE+OO 1.86E-04 7.1~E-Ol 7.BE-Ol 

2.00E+OO 1. 82E-04 3. 24E-Ol 3. 24E-Ol 

3.00E+OO 1.80E-04 1. 29E-Ol 1.29E-Ol 

4.00E+OO 1.80E-04 4. 89E-02 4.9IE-02 

5.00E+OO I. BOE-04 1. 82E-02 1. 84E-02 

6.00E+OO 1.80E-04 6. 74E-03 6. 92E-03 

7.00E+OO 1.80E-04 2. 49E-03 2. 67E-03 

8.00E+OO 1.80E-04 9.l6E-04 l.lOE-03 

9.00E+OO 1.80E-04 3. 37E-04 S.17E-04 

1.OOE+Ol I. 79E-04 1. 24E-04 3.03E-04 

2.00E+Ol 1. 79E-04 O.OOE+OO 1. 79E-04 

3.00E+Ol 1.7BE-04 O.OOE+OO 1.7BE-04 

4.00E+Ol 1. 78E-04 O.OOE+OO 1. 78E-04 

5.00E+Ol 1.77E-04 O.OOE+OO 1.77E-04 

6.00E+Ol 1. 77 E"':O 4 O.OOE+OO 1.77E-04 

7.00E+Ol 1. 76E-04 O.OOE+OO 1. 76E-04 

8.00E+Ol ·1.76E-04 O.OOE+OO 1. 76E-04 

9.00E+Ol 1. 76E-04 O.OOE+OO 1.76E-04 

1.OOE+02 1. 75E-OI.~ O.OOE+OO 1. 75E-04 

2.00E+02 1.70E-04 O.OOE+OO 1.70E-04 

3.00E+02 1.66E-04 O.OOE+OO i.66E-04 

4.00E+02 1. 62E-04 O.OOE+OO 1. 62E-04 

5.00E+02 1. 58E-04 O.OOE+OO 1. 58E-04 

6.00E+02 1. 55E-04 O.OOE+OO 1.55E-04 

7.00E+02 1. 52E-04 O.OOE+OO 1. 52E-04 

8.00E+02 1.49E-04 O.OOE+OO 1.49E-04 

9.00E+02 1.46E-04 O.OOE+OO 1. 46E-04 

1.00E+03 1.43E-04· O.OOE+OO 1. 43E-04 

2.00E+03 1. 23E-04 O.OOE+OO 1.23E-04 

3.00E+03 1.10E-04 O.OOE+OO 1.lOE-04 

4.00E+03 9. 98E-05 O .. OOE+OO 9. 98E-05 

5.00E+03 9.l1E-05 O.OOE+OO 9.l1E-05 

6.00E+03 8. 34E-05 O.OOE+OO 8. 34E-05 

7.00E+03 7. 64E-05 O.OOE+OO 7. 64E-05 

8.00E+03 7.00E-05 O.OOE+OO 7.00E-05 

9.00E+03 6. 42E-05 O .. OOE+OO 6. 42E-05 

1.OOE+04 5. 89E-05 O.OOE+OO 5.89E-05 

2.00E+04 2. 48E-05 O.OOE+OO 2. 48E-05 

B-680 
INGESTION fl- 2.00E-04 BALFLIPE- 5.13E+12 DAYS mOR.IUH 232 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 3.30E-07 6.10E-04 

2.00E-Ol 1. 49E-06 5.90E-03 

3.00E-Ol 3. 12E-06 1. 94E-02 

4.00E-Ol 4. 88E-06 4. 16E-02 

5.00E-Ol 6. 61E-06 7. 18E-02 

6.00E-Ol 8. 22E-06 1.08E-Ol 

7.00E-Ol 9. 68E-06 1.49E-Ol 

8.00E-Ol l.lOE-05 1. 94E-Ol 

9.00E-Ol 1. 21E-05 2.40E-Ol 

1.00E+00 1. 32E-05 1. 32E-05 2. 87E-Ol 2. 87E-Ol 

2.00E+00 5. 21E-06 1. 84E-05 3.90E-Ol 6. 76E-Ol 

3.00E+00 1. 35E-06 1. 97E-05 1. 95E-Ol 8. 71E-Ol 

4.00E+00 3. 75E-07 2. OlE-OS 7. 98E-02 9.51E-Ol 

5.00E+00 1. 33E-07 2.02E-05 3.07E-02 9. 82E-Ol 

6.00E+00 7.18E-08 2.03E-05 1. 15E-02 9. 93E-Ol 

7.00E+00 5. 65E-08 2.03E-05 4. 26E-03 9.97E-Ol 

8.00E+00 5.27E-08 2.04E-05 1.57E-03 9. 99E-Ol 

9.00E+00 5. 17E-08 2.05E-05 5. 79E-04 9. 99E-Ol 

1.00E+Ol 5. 14E-08 2.05E-05 2. 13E-04 1.00E+00 

2.00E+Ol 5.lOE-08 2.lOE-05 1.02E-08 1.00E+00 

3.00E+Ol 5.06E-08 2. 15E-05 O.OOE+OO 1.00E+00 

4.00E+Ol 5.02E-08 2.20E-05 O.OOE+OO 1.00E+00 

5.00E+Ol 4.98E-08 2. 25E-05 O.OOE+oo 1.00E+00 

6.00E+Ol 4. 94E-08 2.30E-05 O.OOE+OO 1.00E+00 

7.00E+Ol 4.90E-08 2. 35E-05 O.OOE+oo 1.00E+00 

8.00E+Ol 4. 87E-08 2.40E-05 O.OOE+OO 1.00E+00 

9.00E+Ol 4. 83E-08 2. 45E-05 O.OOE+oo 1.00E+00 

1.00E+02 4. 79E-08 2.50E-05 O.OOE+OO 1.00E+00 

2.00E+02 4. 44E-08 2. 96E-05 O.OOE+OO 1.00E+00 

3.00E+02 4. 13E-08 3. 39E-05 O.OOE+OO 1.00E+00 

4.00E+02 3. 84E-08 3.78E-05. O.OOE+OO 1.00E+00 

5.00E+o2 3. 58E-08 4. 15E-05 O.OOE+OO 1.00E+00 

6.00E+02 3. 34E-08 4.50E-05 O.OOE+oo 1.00E+00 

7.00E+02 3. 12E-08 4. 82E-05 O.OOE+OO 1.00E+00 

8.00E+02 2. 93E-08 5. 13E-05 O.OOE+oo 1.00E+00 

9.00E+02 2. 75E-08 5.41E-05 O.OOE+OO 1.00E+00 

1.00E+03 2. 58E-08 5. 67E-05 O.OOE+oo 1.00E+00 

2.00E+03 1. 57E-08 7. 67E-05 O.OOE+OO 1.00E+00 

3.00E+03 1. 14E-08 9.00E-05 O.OOE+OO 1.00E+00 

B-681 
INGESTION fl- 2.00E-04 HALFLIFE- 2.41E+Ol DAYS THORIUM 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-01 5.92E-05 9. 96E-01 9. 97E-01 

2.00E-01 1. 18E-04 9.88E-01 9.88E-Ol 

3.00E-01 1.52E-04 9.72E-01 9.72E-01 

4.00E-01 1. 69E-04 9.47E-01 9.47E-Ol 

5.00E-Ol 1.78E-04 9. 15E-Ol 9. 15E-Ol 

6.00E-01 1.81E-04 8.76E-Ol 8. 76E-Ol 

7.00E-01 1.83E-04 8.33E-Ol 8.34E-Ol 

8.00E-01 1. 83E-04 7.88E-Ol 7.88E-Ol 

9.00E-Ol 1.82E-04 7.41E-Ol 7.41E-Ol 

1.00E+00 1.81E-04 6.93E-Ol 6. 93E-01 

2.00E+00 1.71E-04 3.06E-01 3.06E-Ol 

3.00E+00 1. 65E-04 1.18E-01 1.18E-01 

4.00E+00 1.60E-04 4.36E-02 4.37E-02 

5.00E+00 1.56E-04 1.58E-02 1. 59E-02 

6.00E+00 1.51E-04 5.67E-03 5. 82E-03 

7.00E+00 1.47E-04 2.03E-03 2. 18E-03 

8.00E+00 1.43E-04 7. 27E-04 8.70E-04 

9.00E+00 1. 39E-04 2.60E-04 3. 99E-04 

1.00E+Ol 1.35E-04 9.30E-05 2. 28E-04 

2.00E+Ol 1.01E-04 O.OOE+OO 1.01E-04 

3.00E+Ol 7. 53E-05 O.OOE+OO 7. 53E-05 

4.00E+01 5. 63E-05 O.OOE+OO 5.63 

5.00E+Ol 4.21E-05 O.OOE+OO 4.21 

6.00E+Ol 3. 15E-05 O.OOE+OO 3. 15E-05 

7.00E+Ol 2. 36E-05 O.OOE+OO . 2. 36E-05 

8.00E+Ol 1. 76E-05 O.OOE+OO 1. 76E-05 

9.00E+Ol 1.32E-05 O.OOE+OO 1.32E-05 

1.00E+02 9. 86E-06 O.OOE+OO 9. 86E-06 

2.00E+02 5.41E-07 O.OOE+OO 5. 41E-07 

3.00E+02 2.97E-08 O.OOE+OO 2. 97E-08 

B-682 
INGESTION fl= 2.00E-04 BALFLlFE= 2.41E+Ol DAYS 'DlORIUH 234 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 3. 29E-07 6.0BE-04 

2.00E-Ol 1.4BE-06 5.B7E-03 

3.00E-Ol 3.09E-06 1. 92E-02 

4.00E-Ol 4.B3E-06 4.llE-02 

5.00E-Ol 6. 52E-06 7.07E-02 

6.00E-Ol B.OBE-06 1.06E-Ol 

7.00E-Ol 9. 49E-06 1.46E-Ol 

B.OOE-Ol 1.07E-05 1.B9E-Ol 

9.00E-Ol 1.lBE-05 2.34E-Ol 

1.OOE+OO 1.2BE-05 1.2BE-05 2.7BE-Ol 2.7BE-Ol 

2.00E+OO 4. 92E-06 1. 73E-05 3.68E-0l 6.3BE-Ol 

3.00E+OO 1.23E-06 1. BlE-05 1. 79E-Ol 7.99E-Ol 

4.00E+OO 3. 35E-07 1. 79E-05 7.l2E-02 B.4BE-Ol 

5.00E+OO 1.15E-07 1. 75E-05 2. 66E-02 B.50E-Ol 

6.00E+OO 6.04E-OB 1.7lE-05 9. 66E-03 B.36E-Ol 

7.00E+OO 4. 62E-OB 1. 66E-05 3.4BE-03 B.15E-Ol 

B.OOE+OO 4.l9E-OB 1. 62E-05 1.25E-03 7. 94E-Ol 

9.00E+OO 3. 99E-OB 1.5BE-05 4.47E-04 7.72E-Ol 

1.OOE+Ol 3. B6E-OB 1. 54E-05 1.60E-04 7.50E-Ol 

2.00E+Ol 2.B7E-OB 1.lBE-05 O.OOE+OO 5.62E-Ol 

3.00E+Ol 2.l3E-OB 9.0BE-06 O.OOE+OO 4.22E-Ol 

4.00E+Ol 1. 59E-OB 6. 97E-06 O.OOE+OO 3.l6E-Ol 

5.00E+Ol 1.lBE-OS 5. 35E-06 O.OOE+OO 2.37E-Ol 

B-6S3 
INGESTION fl= 1.00£-03 IJALPLIPE- 1.20£+07 DAYS PROTACTINIUM 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------~-------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2.8SE-04 . - 9.99E-OI 9. 99E-OI 

2.00E-OI S.42E-04 9. 93E-OI 9.94E-OI 

3.00E-Ol 6.6IE-04 9.80E-OI 9.8IE-Ol 

4.00E-OI ' 7.0IE-04 9.S8E-OI 9.S8E-OI 

S.OOE-OI 7.03E-04 9.27E-OI 9. 28E";'OI 

6.00E-Ol 6. 88E-04 8.9IE-Ol 8. 92E-OI 

7.00E-OI 6. 69E-04 8. SOE-OI 8.S0E-OI 

8.00E-Ol 6. 49E-04 8.05E-OI 8.06E-OI 

9.00E-OI 6.31E-04 7. S9E-OI 7.60E-OI 

I.OOE+OO 6.16E-04 7.l3E-OI 7.13E-OI 

2.00E+OO S.60E-04 3. 23E-Ol 3. 24E-Ol 

3.00E+OO 5.49E-04 1. 29E-Ol 1. 29E-Ol 

4.00E+OO S.42E-04 4. 88E-02 4. 94E-02 

5.00E+OO 5. 36E-04 I. 82E-02 1. 87E-02 

6.00E+OO 5.30E-04 6. 74E-03 7. 27E-03 

7.00E+OO S.24E-04 2. 48E-03 3.0IE-03 

8.00E+OO S.19E-04 9.1SE-04 1.43E-03 

9.00E+OO S.14E-04 3. 37E-04 8.S1E-04 

1.OOE+Ol 5.lOE-04 1.24E-04 6.34E-04 

2.00E+OI 4. 76E-04 O.OOE+OO 4. 76E-04 

3.00E+Ol 4. 57E-04 O.OOE+OO 4.57E-04 

4.00E+OI 4.4SE-04 O.OOE+OO 4. 45E-04 

S.OOE+Ol 4.37E-04 O.OOE+OO 4. 37E-04 

6.00E+Ol 4. 32E-04 O.OOE+OO 4. 32E-04 

7.00E+Ol 4. 27E-04 O.OOE+OO 4.27E-04 

8.00E+OI 4. 24E-04 O.OOE+OO 4. 24E-04 

9.00E+Ol 4.21E-04 O.OOE+OO 4.21E-04 

1.OOE+02 4.19E-04 O.OOE+OO 4.19E-04 

2.00E+02 4.04E-04 O.OOE+OO 4.04E-04 

3.00E+02 4.00E-04 O.OOE+OO 4.00E-04 

4.00E+02 3. 98E-04 O.OOE+OO 3.98E-04 

S.OOE+02 3. 96E-04 O.OOE+OO 3. 96E-04 

6.00E+02 3. 96E-04 O.OOE+OO 3. 96E-04 

7.00E+02 3. 95E-04 O.OOE+OO 3. 95E-04 

8.00E+02 3. 94E-04 O.OOE+OO 3.94E-04 

9.00E+02 3. 93E-04 O.OOE+OO 3. 93E-04 , ,', 

I.OOE+03 3. 92E-04 O.OOE+OO 3. 92E-04 

2.00E+03 3.8SE-04 O.OOE+OO 3. 85E-04 

3.00E+03 3. 78E-04 O.OOE+OO 3.78E-04 

4.00E+03 3.71E-04 O.OOE+OO 3.71E-04 

5.00E+03 3.64E-04 O.OOE+OO 3. 64E-04 

6.00E+03 3. 57E-04 O.OOE+OO 3. 57E-04 

7.00E+03 3. SOE-04 O.OOE+OO 3.50E-04 

8.00E+03 3.43E-04 O.OOE+OO 3. 43E-04 

9.00E+03 3. 37E-04 O.OOE+OO 3.37E-04 

1.00E+04 3.3IE-04 O.OOE+OO 3.31E-04 

2.00E+04 2. 73E-04 O.OOE+OO 2.73E-04 

B-684 
INGESTION £1= 1.00E-03 HALFLU'E= 1.20E+07 DAYS PROTACTINIUM 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.37E-OS 6.l0E-04 

2.00E-Ol S.96E-OS S.90E-03 

3.00E-Ol 1.19E-04 1. 93E-02 

4.00E-Ol 1.7BE-04 4.l6E-02 

S.OOE-Ol 2.3lE-04 7.l7E-02 

6.00E-Ol 2.7SE-04 1.OBE-Ol 

7.00E-Ol 3.l2E-04 1.49E-Ol 

B.OOE-Ol 3.40E-04 1. 94E-Ol 

9.00E-Ol 3. 63E-04 2.40E-Ol 

1.OOE+OO 3. BlE-04 3. BlE-04 2.B6E-Ol 2.B6E-Ol 

2.00E+OO S.94E-OS 4.40E-04 3. B9E-Ol 6. 76E-Ol 

3.00E+OO 1.OSE-OS 4.SlE-04 1.9SE-Ol B.70E-Ol 

4.00E+OO 6.9lE-06 4. SBE-04 7.9BE-02 9.S0E-Ol 

S.OOE+OO. 6.3lE-06 4. 64E-04 3.06E-02 9. BlE:-Ol 

6.00E+OO S.9lE-06 4.70E-04 1.lSE-02 9. 92E-Ol . 7.00E+OO S.SSE-06 4. 76E-04 4.2SE-03 9.97E-Ol 

B.OOE+OO S.22E-06 4.BlE-04 1. S7E-03 9.9BE-Ol 

9.00E+OO 4.90E-06 4.B6E-04 S.7BE-04 9. 99E-Ol 

1.COE+Ol 4.6lE-06 4.90E-04 2. 13E-04 9.99E-Ol 

2.00E+Ol 2.S6E-06 S.24E-04 O.OOE+OO 9.99E-Ol 

3.00E+Ol 1.SOE-06 S.43E-04 O.OOE+OO 9. 99E-Ol 

4.00E+Ol 9.S2E-07 S.SSE-04 O.OOE+OO 9. 99E-Ol 

S.OOE+Ol 6.SSE-07 S.63E-04 O.OOE+OO 9. 99E-Ol 

6.00E+Ol 4.B7E-07 S.6BE-04 O.OOE+OO 9. 99E-Ol 

7.00E+Ol 3.B6E-07 S.73E-04 O.OOE+OO 9. 99E-Ol 

B.OOE+Ol 3.2lE-07 S.76E-04 O.OOE+OO 9. 99E-Ol 

9.00E+Ol 2. 74E-07 S.79E-04 O.OOE+OO 9. 99E-Ol 

1.OOE+02 2. 39E-O} S.BlE-04 O.OOE+OO 9.99E-Ol 

2.00E+02 7. 77E-OB S.9SE-04 O.OOE+OO 9. 99E-Ol 

3.00E+02 2.9SE-OB 6.00E-04 O.OOE+OO 9. 99E-Ol 

4.00E+02 1.44E-OB 6.02E-04 O.OOE+OO 9. 99E-Ol 

B-6BS 
INGESTION fl= 5.ooE-02 BALPLIFE= 5.79E+07 DAYS URANIUM 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -----------------------------------------------------~-- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI I.4SE-02 9. S4E-0l 9. 99E-OI 

2.00E-OI 2. 76E-02 9. 63E-OI 9.9IE-OI 

3.00E-OI 3.3IE-02 9.4IE-OI 9.74E-OI 

4.00E-OI 3. 44E-02 9.ISE-OI 9.49E-OI 

S.OOE-OI 3.3SE-02 S.S3E-OI 9. 17E-OI 

6.00E-OI 3.24E-02 S.46E-Ol S.79E-Ol 

7.00E-Ol 3.07E-02 S.06E-Ol S.37E-Ol 

S.OOE-Ol 2.9IE-02 7. 63E-OI 7. 92E-Ol 

9.00E-Ol 2. 77E-02 7.l9E-OI 7.4lE-OI 

1.OOE+OO 2.6SE-02 6. 74E-OI 7.0lE-OI 

2.00E+OO 2.0SE-02 3.0SE-OI 3. 26E-OI 

3.00E+OO 1.90E-02 I.2IE-OI I.40E-OI 

4.00E+OO 1.77E-02 4.60E-02 6. 37E-02 

S.OOE+OO 1. 66E-02 1.71E-02 3. 37E-02 

6.00E+OO 1. S5E-02 6. 34E-03 2.19E-02 

7.00E+OO 1. 46E-02 2. 34E-03 1. 69E-02 

S.OOE+OO 1. 37E-02 S.6IE-04 1. 46E-02 

9.00E+OO I.29E-02 3.17E-04 I.32E-02 

I.OOE+OI 1.22E-02 I.I7E-04 I. 23E-02 

2.00E+OI 7.4SE-03 O.OOE+OO 7. 45E-03 

3.00E+Ol S.14E-03 O.OOE+OO S.I4E-03 

4.00E+OI 3.S3E-03 O.OOE+OO 3.S3E~03 

S.OOE+OI 3.0IE-03 O.OOE+OO 3.0IE-03 

6.00E+OI 2.46E-03 O.OOE+OO 2. 46E-03 

7.00E+OI 2.0SE-03 O.OOE+OO 2.0SE-:-03 

B.OOE+OI I.S2E-03 ·O.OOE+OO I.B2E-03 

9.00E+OI 1. 63E-03 O.OOE+OO 1: 63E-03 

I.OOE+02 I.SOE-03 O.OOE+OO I.SOE-03 

2.00E+02 I.lBE-03 O.OOE+OO I.ISE-03 

3.00E+02 l.lSE-03 O.OOE+OO 1. ISE-03 

4.00E+02 I.I3E-03 O.OOE+OO I.I3E-03 

5.00E+02 1.llE-03 O.OOE+OO I.llE-03 

6.00E+02 1. IOE-03 O.OOE+OO l.lOE-03 

7.00E+02 I.OBE-03 O.OOE+OO 1.OSE-03 

8.00E+02 1.07E-03 O.OOE+OO 1.OlE-03 

9.00E+02 I.OSE-03 O.OOE+OO 1.OSE-03 

I.OOE+03 I.03E-03 O.OOE+OO I.03E-03 

2.00E+03 B.92E-04 O.OOE+OO B.92E-04 

3.00E+03 7.72E-04 O.OOE+OO 7.72E-04 

4.00E+03 6. 69E-04 O.OOE+OO 6. 69E-04 

S.OOE+03 S.BOE-04 O.OOE+OO S.SOE-04 

6.00E+03 S.04E-04 O.OOE+OO S.04E-04 

7.00E+03 4.3BE-04 O.OOE+OO 4.3BE-04 

B.OOE+03 3.SIE-04 O.OOE+OO 3.SIE-04 

9.00E+03 3.3IE-04 O.OOE+OO 3.3IE-04 

I.OOE+04 2.BBE-04 O.OOE+OO. 2. BSE-04 

2.00E+04 7. 19E-OS O.OOE+OO 7. 19E-OS 

B-6S6 
INGESTION fl= 5.00£-02 IlALFLIFE= 5.79£+07 DAYS DKAHIOM 233 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 7.60E-04 6.06E-04 

2.00E-Ol 3. 32E-03 5.S3E-03 

3.00E-Ol 6.7lE-03 1.90E-02 

4.00E-Ol 1.02E-02 4.07E-02 

5.00E-Ol 1.33E-02 6. 99E-02 

6.00E-Ol 1.6lE-02 1.05E-Ol 

7.00E-Ol 1. S5E-02 1.45E-Ol 

S.OOE-Ol 2.04E-02 1.S7E-Ol 

9.00E-Ol 2.20E-02 2.3lE-Ol 

1.OOE+OO 2. 34E-02 2. 34E-02 2. 76E-Ol 2. 76E-Ol 

2.00E+OO 5.77E-03 2. 92E-02 3.69E-Ol 6.45E-Ol 

3.00E+OO 1.S3E-03 3.l0E-02 1.S4E-Ol S.29E-Ol 

4.00E+OO 1.30E-03 3.23E-02 7.52E-02 9.04E-Ol 

5.00E+OO 1.15E-03 3. 34E-02 2.S9E-02 9.33E-Ol 

6.00E+OO 1.04E-03 3. 45E-02 1.OSE-02 9.44E-Ol 

7.00E+OO 9. 49E-04 .3.54E-02 4.00E-03 9.4SE-Ol 

S.OOE+OO S.66E-04 3. 63E-02 1.4SE-03 9.49E-Ol 

9.00E+OO 7. 92E-04 3.7lE-02 5. 44E-04 9.50E-Ol 

1.OOE+Ol 7. 25E-04 3.7SE-02 2.00E-04 9.50E-Ol 

2.00E+Ol 3. 27E-04 4. 25E-02 O.OOE+OO 9.50E-Ol 

3.00E+Ol 1. 73E-04 4. 49E-02 O.OOE+OO 9.50E-Ol 

4.00E+Ol 1.04E-04 4. 62E-02 O.OOE+OO 9.50E-Ol 

5.00E+Ol 6. 76E-05 4.70E-02 O.OOE+OO 9.50E-Ol 

6.00E+Ol 4.6lE-05 4. 75E-02 O.OOE+OO 9.50E-Ol 

7.00E+Ol 3.20E-05 4. 79E-02 O.OOE+OO 9.50E-Ol 

S.OOE+Ol 2. 25E-05 4.S2E-02 O.OOE+OO 9.50E-Ol 

9.00E+Ol 1. 59E-05 4.S4E-02 O.OOE+OO 9.50E-Ol 

1.OOE+02 1.l3E-05 4.S5E-02 O.OOE+OO 9.50E-Ol 

2.00E+02 5. 24E-07 4.SSE-02 O.OOE+OO 9.50E-Ol 

3.00E+02 1.S5E-07 4.S9E-02 O.OOE+OO 9.50E-Ol 

4.00E+02 1.7lE-07 4.S9E-02 O.OOE+OO 9.50E-Ol 

5.00E+02 1.6SE-07 4.S9E-02 O.OOE+OO 9.50E-Ol 

6.00E+02 1.65E~07 4.S9E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 1. 62E-07 4.S9E-02 O.OOE+OO 9.50E-Ol .. ', S.OOE+02 1. 59E-07 4.S9E-02 O.OOE+OO 9.50E-Ol .,. 9.00E+02 1. 57E-07 4.S9E-02 O.OOE+OO 9.50E-Ol 

1.OOE+03 1. 54E-07 4.90E-02 O.OOE+OO 9.50E-Ol 

2.00E+03 1.30E-07 4.9lE-02 O.OOE+OO 9.50E-Ol 

3.00E+03 1.llE-07 4. 92E-02 O.OOE+OO 9.50E-Ol 

4.00E+03 9. 53E-OS 4. 93E-02 O.OOE+OO 9.50E-Ol 

5.00E+03 S.2lE-OS 4. 94E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 6.l4E-OS 4. 96E-02 O.OOE+OO 9.50E-Ol 

S.OOE+03 5. 32E-OS 4. 96E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 4. 62E-OS 4. 97E-02 O.OOE+OO 9.50E-Ol 

1.OOE+04 4.0lE-OS 4. 97E-02 O.OOE+OO 9.50E-Ol 

B-6S7 
INGESTION £1- 5.00E-02 RALFLIrE- 2.57E+ll DAYS URANIUH 235 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.-00E-01 1. 48E-02 9. 84E-01 9.99E-01 

2.00E-01 2. 76E-02 9.63E-01 9.91E-01 

3.00E-01 3. 31E-02 9.41E-01 9. 74E-Ol 

4.00E-01 3. 44E-02 9. 15E-Ol 9.49E-Ol 

5.00E-Ol 3. 38E-02 8.83E-Ol 9.17E-Ol 

6.00E-01 3. 24E-02 8.46E-01 8. 79E-Ol 

7.00E-Ol 3.07E-02 8.06E-01 8. 37E-Ol 

8.00E-01 2.91E-02 7. 63E-01 7.92E-01 

9.00E-01 2. 77E-02 7. 19E-01 7.47E-01 

1.00E+00 2. 65E-02 6. 74E-01 7.01E-01 

2.00E+00 2.08E-02 3.05E-01 3. 26E-01 

3.00E+00 1.90E-02 1.21E-01 1.40E-Ol 

4.00E+00 1.77E-02 4.60E-02 6. 37E-02 

5.00E+00 1. 66E-02 1.71E-02 3.37E-02 

6.00E+00 1. 55E-02 6. 34E-03 2. 19E-02 

7.00E+00 1.46E-02 2. 34E-03 1.69E-02 

8.00E+00 1. 37E-02 8. 61E-04 1. 46E-02 

9.00E+00 1. 29E-02 3. 17E-04 1. 32E-02 

1.00E+Ol 1. 22E-02 1. 17E-04 1.23E-02 

2.00E+01 7.45E-03 O.OOE+OO 7.45E-03 

3.00E+Ol 5. 14E-03 O.OOE+OO 5. 14E-03 

4.00E+01 3. 83E-03 O.OOE+OO 3. 83E-03 

5.00E+01 3.01E-03 O.OOE+OO 3.01E-03 

6.00E+01 2.46E-03 O.OOE+OO 2. 46E-03 

7.00E+01 ·2.08E-03 O.OOE+OO 2.08E-03 

8.00E+01 1.82E-03 O.OOE+OO 1. 82E-03 

9.00E+01 1. 63E-03 O.OOE+OO 1.63E-03 

1.00E+02 1.50E-03 O.OOE+OO 1.50E-03 

2.00E+02 1. 18E-03 O.OOE+OO 1. 18E-03 

3.00E+02 1. 15E-03 O.OOE+OO 1. 15E-03 

4.00E+02 1. 13E-03 O.OOE+OO 1. 13E-03 

5.00E+02 1. 11E-03 . O.OOE+OO 1. 11E-03 

6.00E+02 1.10E-03 O.OOE+OO 1.10E-03 

7.00E+02 1.08E-03 O.OOE+OO 1.08E-03 

8.00E+02 1.07E-03 O.OOE+OO 1.07E-03 

9.00E+02 1.05E-03 O.OOE:'-OO 1.05E-03 

1.00E+03 1.03E-03 O.OOE+OO 1.03E-03 " 'J 2.00E+03 8. 92E-04 O.OOE+OO 8. 92E-04 

3.00E+03 7.72E-04 O.OOE+OO 7.72E-04 

4.00E+03 6. 69E-04 O.OOE+OO 6. 69E-04 

5.00E+03 5.80E-04 O.OOE+OO 5.80E-04 

6.00E+03 5.04E-04 O.OOE+OO 5.04E-04 

7.00E+03 4. 38E-04 O.OOE+OO 4. 38E-04 

8.00E+03 3.81E-04 O.OOE+OO 3. 81E-04 

9.00E+03 3. 31E-04 O.OOE+OO 3. 31E-04 

1.00E+04 2. 88E-04 O.OOE+OO 2. 88E-04 

2.00E+04 7. 19E-05 O.OOE+OO 7. 19E-05 

B-688 
INGISTIOR fl- 5.00E-02 B&LrLIPE- 2.578+11 DAYS lJRAtfIUM 2J5 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 7.60E-04 6.06E-04 

2.00E-Ol J.J2E-OJ S.8JE-OJ 

J.OOE-Ol 6.7lE-OJ 1.90E-02 

4.00E-Ol 1.02E-02 4.07E-02 

S.OOE-Ol 1. 33E-02 6. 99E-02 

6.00E-OI 1.6IE-02 1.OSE-Ol 

7.00E-Ol 1.8SE-02 1.4SE-Ol 

8.00E-Ol 2.04E-02 1.87E-Ol 

9.00E-Ol 2.20E-02 2.3lE-Ol 

1.OOE+OO 2.J4E-02 2.J4E-02 2. 76E-Ol 2. 76E-OI 

2.00E+OO S.77E-03 2. 92E-02 3. 69E-Ol 6.4SE-Ol 

3.00E+OO 1. 83E-03 3.lOE-02 1. 84E-Ol 8. 29E-OI 

4.00E+OO 1.30E-03 3. 23E-02 7. S2E-02 9.04E-Ol 

S.OOE+OO 1.lSE-03 3. 34E-02 2. 89E-02 9.33E-Ol 

6.00E+OO I.04E-03 3.4SE-02 1.08E-02 9.44E-Ol 

7.00E+OO 9. 49E-04 3.S4E-02 4.00E-03 9.48E-Ol 

8.00E+OO 8. 66E-04 3. 63E-02 1. 48E-03 9. 49E-OI 

9.00E+OO 7. 92E-04 3.71E-02 S.44E-04 9.S0E-Ol 

1.OOE+Ol 7.2SE-04 3.78E-02 2.00E-04 9.S0E-Ol 

2.00E+Ol 3. 27E-04 4.2SE-02 O.OOE+OO 9.50E-ol 

3.00E+0l I. 73E-04 4. 49E-02 O.OOE+OO 9.50E-Ol 

4.00E+OI 1.04E-04 4. 62E-02 O.OOE+OO 9.50E-Ol 

5.00E+OI 6. 76E-OS 4.70E-02 O.OOE+OO 9.S0E-Ol 

6.00E+OI 4.6IE-OS 4.7SE-02 O.OOE+OO 9.50E-Ol 

7.00E+Ol 3.20E-OS 4. 79E-02 O.OOE+OO 9.S0E-Ol 

8.00E+OI 2.2SE-OS 4. 82E-02 O.OOE+OO 9.50E-Ol 

9.00E+Ol 1. 59E-OS 4. 84E-02 O.OOE+OO 9.50E-Ol 

I.OOE+02 1.l3E-OS 4.85E-02 O.OOE+OO 9.50E-Ol 

2.00E+02 5. 24E-07 4. 88E-02 O.OOE+OO 9.S0E-Ol 

3.00E+02 1.8SE-07 4.89E-02 O.OOE+OO 9.50E-OI 

4.00E+02 1.71E-07 4. 89E-02 O.OOE+OO 9.S0E-OI 

5.00E+02 I. 68E-07 4.89E-02 O.OOE+OO 9.S0E-Ol 

6.00E+02 1.6SE-07 4. 89E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 1. 62E-07 4. 89E-02 O.OOE+OO 9.S0E-Ol 

8.00E+02 1. 59E-07 4. 89E-02 O.OOE+OO 9.50E-Ol " : 9.00E+02 1.57E-07 4.90E-02 O.OOE+OO 9.50E-Ol 

1.OOE+03 I.S4E-07 4.90E-02 O.OOE+OO 9.50E-OI 

2.00E+03 1.30E-07 4.9lE-02 O.OOE+OO 9.S0E-Ol 

3.00E+03 1.IlE-07 4.92E-02 O.OOE+OO 9. SOE-Ol 

4.00E+03 9. 54E-08 4. 93E-02 O.OOE+OO 9.S0E-Ol 

5.00E+03 S.2lE-OS 4. 94E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 6.l4E-OS 4. 96E-02 O.OOE+OO 9.S0E-Ol 

S.OOE+03 S.J2E-OS 4. 96E-02 O.OOE+OO 9. SOE-Ol 

9.00E+03 4. 62E-OS 4. 97E-02 O.OOE+OO 9.50E-Ol 

1.OOE+04 4.0lE-08 4. 97E-02 O.OOE+OO 9.S0E-Ol 

B-689 
INGESTION £1= 5.00E-02 HALFLIFE= 1.16E+12 DAYS URANIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol I.48E-02 9.84E-Ol 9. 99E-OI 

2.00E-Ol 2. 76E-02 9.63E-OI 9.9IE-OI 

3.00E-Ol 3.3IE-02 9.41E-Ol 9. 74E-Ol 

4.00E-OI 3. 44E-02 9.I5E-Ol 9.49E-Ol 

5.00E-Ol 3 .. 38E-02 8.B3E-Ol 9.17E-Ol 

6.00E-Ol 3. 24E-02 8.46E-OI 8. 79E-OI 

7.00E-Ol 3.07E-02 8.06E-Ol 8. 37E-OI 

8.00E-OI 2.9IE-02 7.63E-OI 7.92E-Ol 

9.00E-0l 2. 77E-02 7.19E-OI 7.47E-Ol 

I.OOE+OO 2. 65E-02 6. 74E-OI 7.0IE-Ol 

2.00E+OO 2.08E-02 3.05E-OI 3.26E-OI 

3.00E+OO I.90E-02 1.2IE-OI 1.40E-OI 

4.00E+OO 1.77E-02 4.60E-02 6. 37E-02 

5.00E+OO 1. 66E-02 I.71E-02 3. 37E-02 

6.00E+OO 1.55E-02 6. 34E-03 2.19E-02 

7.00E+OO I. 46E-02 2. 34E-03 I. 69E-02 

8.00E+OO 1.37E-02 8.6lE-04 l.46E-02 

9.00E+OO 1.29E-02 3.l7E-04 1.32E-02 

1.OOE+Ol 1. 22E-02 1.17E-04 1. 23E"':'02 

2.00E+Ol 7.45E-03 O.OOE+OO 7. 45E-03 

3.00E+Ol 5.14E-03 O.OOE+OO 5.14E-03 

4.00E+OI 3. 83E-03 O.OOE+OO 3. 83E-03 

5.00E+OI 3.0IE-03 O.OOE+OO 3.0lE-03 

6.00E+OI 2. 46E-03 O.OOE+OO 2. 46E-03 

7.00E+OI 2.08E-03 O.OOE+OO 2.08E-03 

8.00E+OI 1.82E-03 O.OOE+OO I. 82E-03 

9.00E+OI I. 63E-03 O.OOE+OO 1. 63E-03 

I.OOE+02 1.50E-03 O.OOE+OO 1.50E-03 

2.00E+02 1.18E-03 O.OOE+OO 1.18E-03 

3.00E+02 1.15E-03 O.OOE+OO 1. 15E-03 

4.00E+02 1.13E-03 O.OOE+OO 1.13E-03 

5.00E+02 1.IlE-03 O.OOE+OO 1.IlE-03 

6.00E+02 1.IOE-03 O.OOE+OO 1.IOE-03 

7.00E+02 I.08E-03 O.OOE+OO I.08E-03 

8.00E+02 I.07E-03 O.OOE+OO I.07E-()3 

9.00E+02 I.05E-03 O.OOE+OO I.05E-03 

I.OOE+03 I.03E-03 O.OOE+OO I.03E-03 

2.00E+03 8. 92E-04 O.OOE+OO 8. 92E-04 

3.00E+03 7. 72E-04 O.OOE+OO 7. 72E-04 

4.00E+03 6. 69E-04 O.OOE+OO 6.69E-04 

5.00E+03 5.80E-04 O.OOE+OO 5. BOE-04 

6.00E+03 5.04E-04 O.OOE+OO 5.04E-04 

7.00E+03 4. 38E-04 O.OOE+OO 4. 38E-04 

8.00E+03 3. BIE-04 O.OOE+OO 3.8IE-04 

9.00E+03 3.3IE-04 O.OOE+OO 3.3IE-04 

I.OOE+04 2. 88E-04 O.OOE+OO 2. 88E-04 

2.00E+04 7.19E-05 O.OOE+OO 7.I9E-05 

B-690 
INGESTION fl- 5.ooE-02 ifALFLIFE- 1. 16£+ 12 DAYS IJRABIUM 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYS'rEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.00E-Ol 7.60E-04 6.06E-04 

2.00E-Ol 3. 32E-03 5. 83E-03 

3.00E-Ol 6.71E-03 1.90E-02 

4.00E-Ol 1.02E-02 4.07E-02 

5.00E-Ol 1. 33E-02 6. 99E-02 

6.00E-Ol 1.61E-02 1.05E-Ol 

7.00E-Ol 1.85E-02 1.45E-Ol 

8.00E-Ol 2.04E-02 1.87E-Ol 

9.00E-Ol 2.20E-02 2.31E-Ol 

1.00E+00 2. 34E-02 2. 34E-02 2. 76E-Ol 2. 76E-Ol 

2.00E+00 5.77E-03 2. 92E-02 3.69E-Ol 6. 45E-Ol 

3.00E+00 1. 83E-03 3.10E-02 1.84E-Ol 8.29E-Ol 

4.00E+00 1.30E-03 3. 23E-02 7.52E-02 9.04E-Ol 

5.00E+00 1. 15E-03 3. 34E-02 2. 89E-02 9. 33E-Ol 

6.00E+00 1.04E-03 3. 45E-02 1.08E-02 9. 44E-Ol 

7.00E+00 9. 49E-04 3. 54E-02 4.00E-03 9.48E-Ol 

8.00E+00 8. 66E-04 3.63E-02 1.48E-03 9. 49E-Ol 

9.00E+00 7. 92E-04 3. 71E-02 5. 44E-04 9.50E-Ol 

1.00E+Ol 7. 25E-04 3. 78E-02 2.00E-04 9.50E-Ol 

2.00E+Ol 3. 27E-04 4. 25E-02 O.OOE+OO 9.50E-ol 

3.00E+Ol 1. 73E-04 4. 49E-02 O.OOE+OO 9.50E-Ol 

4.00E+Ol 1.04E-04 4. 62E-02 O.OOE+OO 9.50E-Ol 

5.00E+Ol 6.76E-05 4.70E-02 O.OOE+OO 9.50E-Ol 

6.00E+Ol 4. 61E-05 4. 75E-02 O.OOE+OO 9.50E-Ol 

7.00E+Ol 3.20E-05 4. 79E-02 O.OOE+OO 9.50E-Ol 

8.00E+Ol 2. 25E-05 4. 82E-02 O.OOE+OO 9.50E-Ol. 

9.00E+Ol 1. 59E-05 4. 84E-02 O.OOE+OO 9.50E-Ol 

1.00E+02 1. 13E-05 4. 85E-02 O.OOE+OO 9.50E-Ol 

2.00E+02 5. 24E-07 4. 88E-02 O.OOE+OO 9.50E-Ol 

3.00E+02 1.85E-07 4. 89E-02 O.OOE+OO 9.50E-ol 

4.00E+02 1.71E-07 4.89E-02 O.OOE+OO 9.50E-Ol 

5.00E+02 1. 68E-07 4. 89E-02 O.OOE+OO 9.50E-Ol 

6.00E+02 1.65E-07 4. 89E-02 O.OOE+OO 9.50E-Ol 

7.00E+02 1. 62E-07 4. 89E-02 O.OOE+OO 9.50E-Ol 

8.00E+02 1.59E-07 4. 89E-02 O.OOE+OO 9.50E-Ol 

9.00E+02 1. 57E-07 4.90E-02 O.OOE+OO 9.50E-Ol 

1.00E+03 1. 54E-07 4.90E-02 O.OOE+OO 9.50E-Ol 

2.00E+03 1.30E-07 4.91E-02 O.OOE+OO 9.50E-Ol 

3.00E+03 1. llE-07 4. 92E-02 O.OOE+OO 9.50E-Ol 

4.00E+03 9. 54E-08 4. 93E-02 O.OOE+OO 9.50E-Ol 

5.00E+03 8. 21E-08 4. 94E-02 O.OOE+OO 9.50E-Ol 

7.00E+03 6. 14E-08 4. 96E-02 O.OOE+OO 9.50E-Ol 

8.00E+03 5.32E-08 4.96E-02 O.OOE+OO 9.50E-Ol 

9.00E+03 4. 62E-08 4. 97E-02 O.OOE+OO 9.50E-Ol 

1.00E+04 4.01E-08 4. 97E-02 O.OOE+OO 9.50E-Ol 

B-691 
IHGESTIOB f1- 1.00E-02 BALPLIn- 7.818+08 DAYS rtllPrulllUIi 231 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2. 98E-03 9. 96E-Ol 9. 99E-Ol 

2.00E-Ol 5.9lE-03 9. 88E":,,,Ol 9. 94E-Ol 

3.00E-Ol 7. 56E-03 9.73E-Ol 9.80E-Ol 

4.00E-Ol 8.40E-03 9.50E-Ol 9. 58E-Ol 

5.00E-Ol 8. 82E-03 9.l9E-0l 9. 28E-0l 

6.00E-Ol 9.02E-03 8. 83E-Ol 8. 92E-Ol 

7.00E-Ol 9.09E-03 8. 42E-Ol 8.SlE-Ol 

8.00E-Ol 9.l2E-03 7. 98E-Ol 8.07E-Ol 

9.00E-Ol 9.llE-03 7.S2E-Ol 7.6lE-Ol 

1.OOE+OO 9.lOE-03 7.06E-Ol 7.1SE-Ol 

2.00E+OO 9.0lE-03 3.20E-Ol 3. 29E-Ol 

3.00E+OO 9.00E-03 1. 27E-Ol 1. 36E-Ol 

4.00E+OO 9.00E-03 4. 83E-02 5. 73E-02 

5.00E+OO 9.00E-03 1.80E-02 2.70E-02 

6.00E+OO 9.00E-03 6. 66E-03 l.S7E-02 

7.00E+OO 9.00E-03 2. 46E-03 l.l5E-02 

8.00E+OO 9.00E-03 9.0SE-04 9.9lE-03 

9.00E+OO 9.00E-03 3. 33E-04 9. 33E-03 

1.OOE+Ol 9.00E-03 1. 23E-04 9.l2E-03 

2.00E+Ol 9.00E-03 O.OOE+OO 9.00E-03 

3.00E+Ol 8. 99E-03 O.OOE+OO 8. 99E-03 

4.00E+Ol 8. 99E-03 O.OOE+OO 8. 

S.OOE+Ol 8. 99E-03 O.OOE+OO 8.99E-03 

6.00E+Ol 8. 99E-03 O.OOE+OO 8. 99E-03 

7.00E+Ol 8. 98E-03 O.OOE+OO 8. 98E-03 

8.00E+Ol 8. 98E-03 O.OOE+OO 8. 98E-03 

9.00E+Ol 8. 98E-03 O.OOE+OO 8. 98E-03 

1.OOE+02 8. 97E-03 O.OOE+OO 8. 97E-03 

2.00E+02 8.94E-03 O.OOE+OO 8. 94E-03 

3.00E+02 8.9lE-03 O.OOE+OO 8.9lE-03 

4.00E+02 8. 88E-03 O.OOE+OO 8. 88E-03 

5.00E+02 8. 86E-03 O.OOE+OO 8. 86E-03 

6.00E+02 8. 83E-03 O.OOE+OO 8. 83E-03 

7.00E+02 8.80E-03 O.OOE+OO 8.80E-03 

8.00E+02 8.77E-03 O.OOE+OO 8.77E-03 

9.00E+02 8. 74E-03 O.OOE+OO 8. 74E-03 

1.OOE+03 8.71E-03 O.OOE+OO 8.7lE-03 

2.00E+03 8.43E-03 O.OOE+OO 8.43E-03 

3.00E+03 8.16E-03 O.OOE+OO 8.l6E-03 

4.00E+03 7.90E-03 O.OOE+OO 7.90E-03 

5.00E+03 7.65E-03 O.OOE+OO 7.65E-03 

6.00E+03 7.40E-03 O.OOE+OO 7.40E-03 

7.00E+03 7.l7E-03 O.OOE+OO 7.l7E-03 

8.00E+03 6. 95E-03 O.OOE+OO 6. 95E-03 

9.00E+03 6.73E-03 O.OOE+OO 6. 73E-03 

1.OOE+04 6. 52E-03 O.OOE+OO 6. 52E-03 

2.00E+04 4. 82E-03 O.OOE+OO 4. 82E:"'03 

B-692 
INGESTION fl- 1.00£-02 II&.L¥LIFE- 7.81£+08 DA.YS REPTUlfIUH 237 

, TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-Ol 1. 59E-05 6.25£-04 

2.00E-Ol 6. 89E-05 5. 96E-03 

3.00E-Ol 1. 37E-04 1. 94E-02 

4.00E-Ol 2.05E-04 4. 17E-02 

5.00E-Ol 2. 66E-04 7. 17E-02 

6.00E-Ol 3. 16E-04 1.08E-Ol 

7.00E-Ol 3. 57E-04 1. 49E-Ol 

8.00£-01 3.90E-04 1. 93E-Ol 

9.00E-Ol 4. 15E-04 2. 39E-Ol 

1.00E+00 4. 35E-04 4. 35E-04 2. 85E-Ol 2. 85E-Ol 

2.00E+00 5. 98E-05 4. 94E-04 3. 86E-Ol 6.71E-01 

3.00E+00 3. 96E-06 4. 98E-04 1. 93E-Ol 8. 63E-Ol 

4.00E+00 3. 89E-07 4. 99E-04 7. 89E-02 9.42E-Ol 

5.00E+00 1. 65E-07 4. 99E-04 3.03E-02 9. 72E-ol 

6.00E+00 1.50E-07 4. 99E-04 1. 13E-02 9. 84E-Ol 

7.00E+00 1.50E-07 4. 99E-04 4. 21E-03 9. 88E-Ol 

8.00E+bo 1. 49E-:-07 4. 99E-04 1.55E-03 9.90E-Ol 

9.00E+00 1.49£-07 5.00E-04 5. 72E-04 9.90E-Ol 

1.00E+01. 1. 49E-07 5.00E-04 2. llE-04 9.90E-Ol 

2.00E+Ol 1. 49E-07 5.01E-04 1.59E-07 9. 91E-Ol 

3,,00E+Ol 1. 49E-07 5.03E-04 1. 49E-07 9. 91E-Ol 

4.00E+Ol 1.49£-07 5.04E-04 1.49E-07 9. 91E-Ol 

5.00E+Ol 1. 49E-07 5.06E-04 1.49E-07 9.91E-Ol 

6.00E+Ol 1. 49E-07 5.07E-04 1. 49E-07 9.91E-Ol 

7.00E+Ol 1. 49E-07 5.09E-04 1.49E-07 9. 91E-Ol 

8.00E+Ol 1. 49E-07 5.10E-04 1. 49E-07 9.91E-Ol 

9.00E+Ol 1. 49E-07 5. 12E-04 1.49E-07 9.91E-Ol 

1.00E+02 1. 49E-07 5. 13E-04 1. 49E-07 9.91E-Ol 

2.00E+02 1. 48E-07 5. 28E-04 1.48E-07 9.91E-Ol 

3.00E+02 1.48E-07 5. 43E-04 1. 48E-07 9.91E-ol 

4.00E+02 1. 47E-07 5. 58E-04 1.47E-07 9.91E-Ol 

5.00E+02 1.47E-07 5. 72E-04 1.47E-07 9.91E-ol 

6.00E+02 1.46E-07 5. 87E-04 1.46E-07 9.91E-01 

7.00E+02 1. 45E-07 6.01E-04 1. 45E-07 9.91£-01 

8.00E+02 1. 45E-07 6. 16E-04 1. 45E-07 9.91E-Ol 

9.00E+02 1. 44E-07 6.30E-04 1. 44E-07 9.91E-Ol " . 1.00E+03 1. 44E-07 6. 45E-04 1.44£-07 9.91E-Ol ,.-, ,-- 2.00E+03 1. 38E-07 7. 86E-04 1. 38E-07 9.91E-Ol 

3.00E+03 1. 33E-07 9. 21E-04 1. 33E-07 9. 91E-01 

4.00E+03 1. 28E-07 1.05E-03 1. 28E-07 9.91E-Ol 

5.00E+03 1. 23E-07 1. 18E-03 1.23E-07 9.91E-01 

6.00E+03 1. 18E-07 1.30E-03 1. 18E-07 9.91E-Ol 

7.00E+03 1. 14E-07 1.41E-03 1. 14E-07 9. 91E-01 

8.00E+03 1.10E-07 1. 53E-03 1.10£-07 9. 92E-Ol 

9.00E+03 1.06E-07 1. 63E-03 1.06E-07 9. 92E-Ol 

1.00E+04 1.02E-07 1. 74E-03 1.02E-07 9. 92E-Ol 

2.00E+04 7.06E-08 2. 59E-03 7.06E-08 9. 93E-Ol 

B-693 
INGBSTIOR fl- I.OOE-04 IlALPLIFE- 3.20£+04 DAYS PLUTONIUK 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-0l 2. 98E-05 9.99E-Ol 9. 99E-0l 

2.00E-Ol 6.0lE-05 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 7. 79E-05 9.8lE-0l 9.8lE-Ol 

4.00E-Ol 8.17E-05 9. 58E-Ol 9. 58E-Ol 

5.00E-Ol 9.3lE-05 9. 28E-Ol 9.28E-Ol 

6.00E-Ol 9.60E-05 8. 92E-Ol 8. 92E-Ol 

7.00E-Ol 9. 76E-05 8.50E-O! 8.5!E-0l 

8.00E-Ol· 9. 84E-05 8.06E-Ol 8.06E-0l 

9.00E-Ol 9. 88E-05 7.60E-Ol 7.60E-0l 

1.OOE+OO 9.9lE-05 7.l3E-Ol 7.13E-Ol 

2.00E+OO 9. 89E-05 3. 24E-Ol 3.24E-Ol 

3.00E+OO 9. 86E-05 1. 29E-Ol 1. 29E-Ol 

4.00E+OO 9. 84E-05 4.89E-02 4.90E-02 

5.00E+OO 9. 82E-05 1. 82E-02 1. 83E-02 

6.00E+OO 9.8lE-05 6. 74E-03 6. 84E-03 

7.00E+OO 9.80E-05 2. 49E-03 2. 58E-03 

8.00E+OO 9.80E-05 9.l6E-04 1.OlE-03 

9.00E+OO 9. 79E-Q5 3. 37E-04 4. 35E-04 

1.OOE+Ol 9. 79E-05 1. 24E-04 2. 22E-04 

2.00E+Ol 9. 74E-05 O.OOE+OO 9. 74E-05 

3.00E+Ol 9.11E-05 O.OOE+OO 9.11E-05 

4.00E+Ol 9. 68E-05 O.OOE+OO 9. 68E-05 

5.00E+Ol 9. 66E-05 O.OOE+OO 9. 66E-05 

6.00E+Ol 9. 63E-05 O.OOE+OO 9. 63E-05 

7.00E+OI 9.6lE-05 O.OOE+OO 9.6lE-05 

8.00E+Ol 9.60E-05 O.OOE+OO 9 .. 60E-05 

9.00E+Ol 9. 58E-05 O.OOE+OO 9. 58E-05 

1.OOE+02 9. 56E-05 O.OOE+OO 9. 56E-05 

2.00E+02 9. 42E-05 O.OOE+OO 9. 42E-05 

3.00E+02 9. 32E-05 O.OOE+OO 9. 32E-05 

4.00E+02 9. 23E-05 O.OOE+OO 9. 23E-05 

5.00E+02 9.l5E-05 O.OOE+OO 9.I5E-05 

6.00E+02 9.09E-05 O.OOE+OO 9.09E-05 

7.00E+02 9.03E-05 O.OOE+OO 9.03E-05 

8.00E+02 8. 97E-05 O.OOE+OO 8. 97E-05 

9.00E+02 8. 92E-05 O.OOE+OO 8. 92E-05 

I.OOE+03 8. 88E-05 O.OOE+OO 8. 88E-05 

2.00E+03 8.43E-05 O.OOE+OO 8. 43E-05 

3.00E+03 8.02E-05 O.OOE+OO 8.02E"'05 

4.00E+03 7. 63E-05 O.OOE+OO 7. 63E-05 

5.00E+03 7. 26E-05 O.OOE+OO 7.26E-05 

6.00E+03 6.90E-05 O.OOE+OO 6.90E-05 

7.00E+03 6. 57E-OS O.OOE+OO 6. 57E-OS 

8.00E+03 6. 25E-05 O.OOE+OO 6. 25E-05 

9.00E+03 S.94E-05 O.OOE+OO 5. 94E-OS 

I.OOE+04 5.6SE-05 O.OOE+OO 5. 65E-OS 

2.00E+04 3. 43E-OS O.OOE+OO 3. 43E-05 

B-694 
INGESTION' f l- 1.00£-04 BALFLIFE- 3.20£+04 DAYS PLUTON'IUH 238 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------~----------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.00E-01 6.26E-09 5. 95E-04 

2.00E-Ol 2.9lE-08 5.77E-03 

3.00E-Ol 6. 27E-08 I. 89E-02 

4.00E-OI 1.OlE-07 4.08E-02 

5.00E-OI I. 42E-07 7.04E-02 

6.00E-OI 1. 82E-07 I.06E-Ol 

7.00E-Ol 2. 22E-07 1.90E-OI 

8.00E-Ol 2.60E-07 1.90E-Ol 

9.00E-Ol 2.96E-07 2. 36E-Ol 

1.OOE+OO 3.3lE-07 3.3IE-07 2. 82E-Ol 2. 82E-Ol 

2.00E+OO 2.70E-07 6.0IE-07 3.89E 01 6.71E-Ol 

3.00E+00 I. 67E-07 7.68E-07 1. 97E-=OI 8.68E-Ol 

4.00E+00 1.08E-07 8.77E-07 8.l4E-02 9.50E-0l 

5.00E+OO 7. 42E-08 9.5IE-07 3.14E-02 9.8IE-01 

6.00E+OO S.43E-08 1.01E-06 1.18E-02 9. 93E-OI 

7.00E+OO 4. 26E-08 ~1.05E-06 4. 38E-03 9. 97E"";Ol 

8.00E+OO 3. 55E-08 1.08E-06 1.62E-03 9. 99E-Ol 

9.00E+OO 3.l2E-08 1.11E-06 5. 96E-04 9. 99E-Ol 

1.OOE+Ol 2. 84E-08 1.14E-06 2.20E-04 9. 99E-Ol 

2.00E+Ol 1. 97E-08 1.37E-06 O.OOE+OO 9. 99E-Ol 

3.00E+OI 1. 57E-08 1.S4E-06 O.OOE+OO 9.99E-Ol 

4.00E+OI 1.3IE-08 1. 68E-06 O.OOE+OO 9.99E-Ol 

5.00E+Ol l.13E-08 1.80E-06 O.OOE+OO 9. 99E-Ol 

6.00E+OI 1.OIE-OB 1.9IE-06 O.OOE+OO 9. 99E-OI 

7.00E+Ol 9.17E-09 2.00E-06 O.OOE+OO 9. 99E-OI 

B-695 
INGESTIOII f 1- 1.00E-04 BALFLIFE- 8.78E+06 DAYS PLUTONIUM 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------~---~-------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2. 98E-OS 9. 99E-OI 9.99E-OI 

2.00E-Ol 6.0IE-OS 9.94E-OI 9o94E-OI 

3.00E-Ol 7. 79E-OS 9.8IE-Ol 9.8lE-OI 

4.00E-OI 8.77E-OS 9.S8E-OI 9oS8E-Ol 

S.OOE-Ol 9.3lE-OS 9. 28E-OI 9.28E-Ol 

6.00E-Ol 9.60E-OS 8. 92E-OI 8.92E-OI 

7.00E-OI 9. 76E-OS 8.S0E-OI 8.SIE-Ol 

8.00E-Ol 9.84E-OS B.06E-Ol 8.06E-Ol 

9.00E-Ol 9.88E-OS 7.60E-Ol 7.60E-Ol 

1.OOE+OO 9.9lE-OS 7ol3E-Ol 7.l3E-Ol 

2.00E+OO 9. 89E-OS 3.24E-Ol 3. 24E-Ol 

3.00E+OO 9. 86E-OS 1. 29E-Ol 1.29E-Ol 

4.00E+OO 9_84E-OS 4. 89E-02 4.90E-02 

S.OOE+OO 9. 82E-OS 1.82E-02 1.83E-02 

6.00E+OO 9.8lE-OS 6. 74E-03 6. 84E-03 

7.00E+OO 9.8lE-OS 2. 49E-03 2.S8E-03 

8.00E+OO 9.80E-OS 9.l6E-04 1.OlE-03 

9.00E+OO 9. 79E-OS 3. 37E-04 4.3SE-04 

I.OOE+Ol 9. 79E-OS 1.24E-04 2. 22E-04 

2.00E+OI 9.7SE-OS O.OOE+OO 9.7SE-OS 

3.00E+OI 9.7lE-OS O.OOE+OO 9.7lE-OS 

4.00E+Ol 9. 69E-OS O.OOE+OO 9. 69E-O 

S.OOE+OI 9.67E-05 O.OOE+OO 9. 67E-OS 

6.00E+OI 9. 65E-05 O.OOE+OO 9.6SE-OS 

7.00E+Ol 9. 63E-OS O.OOE+OO 9. 63E-05 

8.00E+Ol 9.6lE-05 O.OOE+OO 9.6lE-05 

9.00E+Ol 9.60E-OS O.OOE+OO 9.60E-OS 

1.OOE+02 9.S8E-05 O.OOE+OO 9. 58E-OS 

2.00E+02 9. 46E-OS O.OOE+OO 9.46E-05 

3.00E+02 9. 38E-OS O.OOE+OO 9. 38E-05 

4.00E+02 9.3lE-05 O.OOE+OO 9.3lE-05 

S.OOE+02 9.2SE-05 O.OOE+OO 9. 25E-05 

6.00E+02 9.2IE-05 O.OOE+OO 9.2IE-05 

7.00E+02 9.l7E-OS O.OOE+OO 9.I7E-OS 

8.00E+02 9.l3E-OS O.OOE+OO 9.13E-05 

9.00E+02 9.l0E-OS O.OOE+OO 9.l0E-05 

'.-:- . 1.OOE+03 9.07E-OS O.OOE+OO 9.07E-05 

2.00E+03 8.8lE-OS O.OOE+OO 8.8lE-05 

3.00E+03 8. 56E-OS O.OOE+OO 8.S6E-OS 

4.00E+03 8. 32E-05 O.OOE+OO 8. 32E-OS 

5.00E+03 8.08E-OS O.OOE+OO 8.08E-05 

6.00E+03 7. 86E-OS O.OOE+OO 7. 86E-05 

7.00E+03 7.64E-OS O.OOE+OO 7.64E-OS 

8.00E+03 7.42E-05 O.OOE+OO 7.42E-OS 

9.00E+03 7.2IE-05 O.OOE+OO 7.21E-OS 

I.OOE+04 7.0IE-OS O.OOE+OO 7.0lE-OS 

2.00E+04 S.27E-OS O.OOE+OO S.27E 

B-696 
INGESTION f 1- 1.00£-04 BALPLIPK- 8.78£+06 DAYS PLUTONIUM 239 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

1.OOE-Ol 6. 26E-09 5. 95E-04 

2.00E-Ol 2.9lE-OS 5.77E-03 

3.00E-Ol 6. 27E-OS 1.S9E-02 

4.00E-Ol 1.OIE-07 4.0SE-02 

5.00E-Ol 1. 42E-07 7.04E-02 

6.00E-Ol 1.S2E-07 1.06E-Ol 

7.00E-OI 2. 22E-07 1.90E-Ol 

S.OOE-Ol 2.60E-07 1.90E-Ol 

9.00E-Ol 2. 96E-07 2. 36E-Ol 

1.OOE+OO 3.3lE-07 3.3lE-07 2.S2E-OI 2.S2E-Ol 

2.00E+OO 2.70E-07 6.0lE-07 3.S9E-Ol 6.7lE-Ol 

3.00E+OO 1. 67E-07 7.6SE-07 1. 97E-Ol S.6SE-Ol 

4.00E+OO 1.OSE-07 s.nE-07 S.14E-02 9.50E-Ol 

5.00E+OO 7. 42E-OS 9.5lE-07 3.l4E-02 9.SlE-Ol 

6.00E+OO 5. 43E-OS 1.OlE-06 1.lSE-02 9. 93E-Ol 

7.00E+OO 4. 26E-OS 1.05E-06 4.3SE-03 9.97E-Ol 

S.OOE+OO 3. 55E-OS 1.08E-06 1.62E-03 9. 99E-Ol 

9.00E+OO 3.l2E-08 1.l1E-06 5. 96E-04 1.OOE-+OO 

1.OOE+Ol 2. 84E-OS 1.14E .... 06 2.20E-04 1.OOE+OO 

2.00E+Ol 1. 97E-OS 1. 37E-06 O.OOE+OO 1.OOE.f.OO 

3.00E+Ol 1. 57E-OS 1. 54E-06 O.OOE+OO 1.OOEtOO 

4.00E+Ol 1.3lE-08 1. 68E-06 O.OOE+OO 1.OOEJ.OO 

5.00E+Ol 1.13E-08 1.SOE-06 O.OOE+OO 1.OOE+OO 

6.00E+Ol 1. OlE-OS 1.9lE-06 O.OOE+OO 1.OOE+OO 

7.00E+Ol 9.l8E-09 2.0lE-06 O.OOE+OO 1.OOE+OO 

'.- " 

B-697 
INGESTION . £1= 1.00E-04 BALFLIFE= 2.39E+06 DAYS PLUTONIUM 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --------------------------------------------------------

SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

I.OOE-OI 2. 98E-OS 9. 99E-OI 9. 99E-OI 

2.00E-Ol 6.01E-05 9. 94E-Ol 9.94E-Ol 

3.00E-Ol 7.79E-05 9.8IE-Ol 9.8IE-OI 

4.00E-OI 8.17E-05 9.S8E-Ol 9. 58E-Ol 

5.00E"-Ol 9.31E-OS 9. 28E-Ol 9. 28E-Ol 

6.00E-Ol 9.60E-05 8.92E-Ol 8. 92E-Ol 

7.00E-Ol 9. 76E-05 8.50E-Ol 8. SIE-OI 

S.OOE-Ol 9. 84E-OS 8.06E-Ol 8.06E-Ol 

9.00E-Ol 9.S8E-OS 7.60E-Ol 7.60E-Ol 

I.OOE+OO 9.9IE-OS 7. 13E-Ol 7. 13E-Ol 

2.00E+OO 9. 89E-OS 3.24E-OI 3. 24E-Ol 

3.00E+OO 9. 86E-OS 1.29E-Ol 1. 29E-Ol 

4.00E+OO 9. 84E-OS 4. 89E-02 4.90E-02 

S.OOE+OO 9. 82E-05 1.82E-02 1. 83E-02 

6.00E+OO 9.8lE-OS 6. 74E-03 6. 84E-03 

7.00E+OO 9.80E-OS 2. 49E-03 2.S8E-03 

8.00E+OO 9.80E-05 9.l6E-04 I.OlE-03 

9.00E+OO 9.79E-05 3. 37E-04 4.3SE-04 

1.OOE+Ol 9. 79E-05 1. 24E-04 2. 22E-04 

2.00E+Ol 9.7SE-OS O.OOE+OO 9.7SE-05 

3.00E+Ol 9.7lE-OS O.OOE+OO 9.11E-05 

4.00E+Ol 9. 69E-OS O.OOE+OO 9. 69E-OS 

S.OOE+Ol 9. 67E-OS O.OOE+OO 9. 67E-05 

6.00E+Ol 9.6SE-05 O.OOE+OO 9.6SE-OS 

7.00E+OI 9. 63E-05 O.OOE+OO 9. 63E-OS 

8.00E+Ol 9.6lE-OS O.OOE+OO 9.6lE-OS 

9.00E+Ol 9.60E-05 O.OOE+OO 9.60E-05 

1.00E+02 9.S8E-05 O.OOE+OO 9. 58E-OS 

2.00E+02 9.46E-OS O.OOE+OO 9. 46E-05 

3.00E+02 9.37E-05 O.OOE+OO 9.37E-OS 

4.00E+02 9.3lE-OS O.OOE+OO 9.3lE-05 

S.OOE+02 9.25E-05 O.OOE+OO 9. 25E-05 

6.00E+02 .9.20E-05 O.OOE+OO 9.20E-OS 

7.00E+02 9.l6E-05 O.OOE+OO 9.l6E-05 

8.00E+02 9.l3E-05 O.OOE+OO 9.l3E-05 

9.00E+02 9.lOE-OS O.OOE+OO 9.lOE-OS 

1.00E+03 9.07E-OS O.OOE+OO 9.07E-05 

3.00E+03 8.S5E-05 O.OOE+OO 8. 55E-05 

4.00E+03 8.3lE-OS O.OOE+OO 8.31E-05 

6.00E+03 7. 85E-OS O.OOE+OO 7. 85E-05 

8.00E+03 7.4lE-05 O.OOE+OO 7.41E-05 

1.00E+04 7.00E-OS O.OOE+OO 7.00E-05 

8-698 
INGESTION f 1- 1.00£-04 BALFLlFE- 2.39£+06 DAYS PLUTONIUM 240 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------

24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS URINE URINE FECES FECES 

I.OOE-OI 6. 26E-09 5.95E-04 

2.00E-OI 2.9IE-08 5.17E-03 

3.00E-0l 6. 27E-08 I.S9E-02 

4.00E-ol I.OIE-07 4.0SE-02 

5.00E-OI I.42E-07 7.04E-02 

6.00E-OI I.S2E-07 I.06E-Ol 

7.00E-OI· 2. 22E-07 I.90E-OI 

S.OOE-OI 2.60E-07 I.90E-OI 

9.00E-OI 2.96E-07 2.36E-Ol 

1.00E+00 3.31E-07 3.3IE-07 2.S2E-OI 2.S2E-OI 

2.00E+00 2.70E-07 6.0IE-07 3.89E-OI 6.11E-OI 

3.00E+00 I.67E-07 7.6SE-07 1.97E-OI S.6SE-OI 

4.00E+00 I.OSE-07 S.77E-07 8. 14E-02 9.50E-Ol 

5.00E+00 7.42E-08 9.5IE-07 3.14E-02 9.81E-OI 

6.00E+00 5. 43E-08 1.0IE-06 I.I8E-02 9.93E-OI 

7.00E+00 4. 26E-oS I.05E-06 4.38E-03 9. 97E-OI 

S.OOE+oo 3. 55E-08 1.08E-06 1. 62E-03 9.99E-Ol 

9.00E+00 3.12E-08 1. 11E-06 5. 96E-04 I.OOE-OO 

I.OOE+OI 2. 84E-08 1. 14E-06 2.20E-04 I.OOE-OO 

2.00E+OI I.97E-08 1. 37E-06 O.OOE+OO 1.00E-00 

3.00E+OI 1.57E-OS I.54E-06 O.OOE+oo 1.00E-00 

4.00E+OI 1.3IE-08 1. 68E-06 O.OOE+OO 1.00E-00 

5.00E+Ol 1.13E-08 I.80E-06 O.OOE+oo I.OOE-OO 

6.00E+Ol 1.0IE-08 1.9IE-06 O.OOE+OO I.OOE-OO 

7.00E+OI 9.18E-09 2.0IE-06 O.OOE+oo 1.00E-00 

B-699 
DIGESTION fl- 1.00E-04 BALPLIFE- 1.37B+08 DAYS PLUTOlRDH 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 2. 98E-05 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 6.0lE-05 9.94E-Ol 9.94E-Ol 

3.00E-Ol 7. 79E-05 9.8lE-Ol 9.8lE-Ol 

4.00E-Ol 8.17E-05 9. 58E-Ol 9. 58E-Ol 

5.00E-Ol 9.3lE-05 9. 28E-Ol 9. 28E-Ol 

6.00E-Ol 9.60E-05 8.92E-Ol 8. 92E-Ol 

7.00E-Ol 9. 76E-05 8.50E-Ol 8.5lE-Ol 

8.00E-Ol 9. 84E-05 8.06E-Ol 8.06E-Ol 

9.00E-0l 9. 88E-05 7.60E-Ol 7.60E-Ol 

1.OOE+OO 9.9lE-05 7. 13E-Ol 7.l3E-Ol 

2.00E+OO 9. 89E-05 3. 24E-Ol 3. 24E-Ol 

3.00E+OO 9. 86E-05 1.29E-Ol 1. 29E-Ol 

4.00E+OO 9. 84E-05 4. 89E-02 4.90E-02 

5.00E+OO 9. 82E-05 1. 82E-02 1. 83E-02 

6.00E+OO 9.81E-05 6. 74E-03 6. 84E-03 

7.00E+OO 9.8lE-05 2. 49E-03 2. 58E-03 

8.00E+OO 9.80E-05 9.l6E-04 1.OlE-03 

9.00E+OO 9. 79E-05 3. 37E-04 4. 35E-04 

1.OOE+Ol 9.79E-05 1.24E-04 2.22E-04 

2.00E+Ol 9.7SE-05 O.OOE+OO 9. 75E-05 

3.00E+Ol 9.11E-05 O.OOE+OO 9.11E-05 

4.00E+Ol 9. 69E-05 O.OOE+OO 9. 69E-05 

5.00E+Ol 9.67E~05 O.OOE+OO 9. 67E-05 

6.00E+Ol 9. 65E-05 O.OOE+OO 9.65E-05 

7.00E+Ol 9. 63E-05 O.OOE+OO 9. 63E-05 

8.00E+Ol 9.6lE-05 O.OOE+OO 9.6lE-OS 

9.00E+Ol 9.60E-05 O.OOE+OO 9.60E-OS 

1.OOE+02 9. 58E-05 O.OOE+OO 9. 58E-OS 

2.00E+02 9. 46E-05 O.OOE+OO 9. 46E-05 

3.00E+02 9. 38E-05 O.OOE+OO 9. 38E-05 

4.00E+02 9.3lE-05 O.OOE+OO 9.3lE-OS 

S.OOE+02 9. 25E-OS O.OOE+OO 9.2SE-OS 

6.00E+02 9.2lE-OS O.OOE+OO 9. 2 IE-OS 

7.00E+02 9. 17E-05 O.OOE+OO 9.l7E-05 

8.00E+02 9.l3E-05 O.OOE+OO 9. 13E-OS 

9.00E+02 9.l0E-OS O.OOE+OO 9.lOE4)S 

1.OOE+03 9.07E-05 O.OOE+OO 9.07E-OS , .: 

2.00E+03 8.8lE-OS O.OOE+OO 8.8lE-05 

3.00E+03 8. 56E-05 O.OOE+OO 8. 56E-OS 

4.00E+03 8. 32E-OS O.OOE+OO 8. 32E-OS 

5.00E+03 8.09E-OS O.OOE+OO 8.09E-OS 

7.00E+03 7. 64E-05 O.OOE+OO 7. 64E-OS 

8.00E+03 7. 43E-OS O.OOE+OO 7.43E-05 

9.00E+03 7. 22E-05 O.OOE+OO 7. 22E-OS 

1.OOE+04 7.02E-05 O.OOE+OO 7.02E-OS 

2.00E+04 5. 28E-OS O.OOE+OO S.28E-OS 

B-100 
.. ,.' ,' . .... 

INGESTION 

TIME AFTER 

S INGLE INTAKE 

DAYS 

1.OOE-Ol 

2.00E-Ol 

3.00E-Ol 

4.00E-Ol 

5.00E-Ol 

6.00E-Ol 

7.00E-Ol 

S.OOE-OI 

9.00E-OI 

1.00E+Ol 

2.00E+00 

3.00E+00 

4.00E+00 

5.00E+00 

6.00E+00 

7.00E+00 

S.OOE+OO 

9.00E+00 

1.00E+Ol 

2.00E+Ol 

3.00E+Ol 

4.00E+Ol 

5.00E+OI 

6.00E+Ol 

7.00E+Ol 

fl- 1.008-04 BA.LFLI.FB= 1.37£+08 DAYS PLUTONIUM 242 

FRACTION OF INITIAL INTAKE IN: 

------------------------------------------------------ 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

URINE URINE FECES FECES 

6. 26E-09 5. 95E-04 

2.9lE-OS 5. 17E-03 

6. 27E-08 1.S9E-02 

1.0IE-07 4.0SE-02 

I.42E-07 7.04E-02 

1.S2E-07 1.06E-Ol 

2. 22E-07 1.90E-01 

2.60E-07 1.90E-01 

2. 96E-07 2. 36E-0l 

3.3IE-07 3.3lE-07 2.S2E-Ol 2.S2E-Ol 

2.70E-07 6.0lE-07 3.S9E 01 6.71E-Ol 

1. 67E-07 7.6SE-07 1. 97E-=01 S.6SE-OI 

1.OSE-07 S.77E-07 S.14E-02 9.50E-OI 

7. 42E-OS 9.5lE-07 3.l4E-02 9.SIE-01 

5. 43E-OS 1.0IE-06 1.lSE-02 9.93E-0l 

4. 26E-OS 1.05E-06 4.3SE-03 9. 97E-OI 

3.55E-OS 1.OSE-06 1. 62E-03 9. 99E-Ol 

3.l2E-OS 1.l1E-06 5. 96E-04 1.OOE+00 

2.S4E-OS 1.14E-06 2.20E-04 1.00E+00 

1.97E-OS 1. 37E-06 O.OOE+OO 1.00EJ.00 

1.57E-OS 1. 54E-06 O.OOE+OO 1.OOE+00 

1.3IE-OS 1.6SE-06 O.OOE+OO I.OOE+OO 

I.l3E-OS 1.80E-06 O.OOE+OO 1.00E+00 

1. OlE-OS 1.9lE-06 O.OOE+OO I.OOE+OO 

9.lSE-09 2.0lE-06 O.OOE+OO 1.00E+00 

B-701 
INGESTION fl- 5.00£-04 BALFLIFE- 2.69£+06 DAYS AMERICIUM 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 1. 48E-04 9.99E-Ol 9. 99E-Ol 

2.00E-Ol 2. 94E-04 9. 94E-Ol 9. 94E-Ol 

3.00E-Ol 3. 76E-04 9.80E-Ol 9.8lE-OI 

4.00E-Ol 4.l9E-04 9. 58E-Ol 9.S8E-Ol 

S.OOE-Ol 4. q.OE-04 9. 28E-Ol 9.28E-Ol 

6.00E-Oi. 4.50E-04 8.9lE-OI 8. 92E-Ol 

7.00E-Ol 4. 54E-04 8.S0E-Ol 8.S1E-0l 

8.00E-Ol 4. 56E--04 8.06E-Ol 8.06E-Ol 

9.00E-Ol 4. 56E-04 7.60E-Ol 7.60E-Ol 

1.00E+OO 4.S5E-04 7. 13E-Ol 7.l4E-OI 

2.00E+OO 4. 51E-04 3. 23E-Ol 3. 24E-Ol 

3.00E+OO 4.S0E-04 1. 29E-Ol 1. 29E-Ol 

4.00E+OO 4.50E-04 4. 89E-02 4. 93E-02 

5.00E+OO 4.50E-04 1. 82E-02 1~87E-02 

6.00E+OO 4.50E-04 6. 74E-03 7. 19E-03 

7.00E+OO 4.50E-04 2. 49E-03 2. 94E-03 

8.00E+OO 4.50E-04 9. 15E-04 1. 37E-03 

9.00E+OO 4.50E-04 3. 37E-04 7. 87E-04 

1.00E+Ol 4.50E-04 1. 24E-04 S.74E-04 

2.00E+Ol 4.50E-04 O.OOE+OO 4.S0E-04 

3.00E+Ol 4.50E-04 O.OOE+OO 4.50E-()4 

4.00E+Ol 4.50E-04 O.OOE+OO 4.50E-04 

5.00E+Ol 4. 49E-04 O.OOE+OO 4. 49E .... 04 

6.00E+Ol 4.49E-04 O.OOE+OO 4. 49E-04 

. 7.00E+Ol 4. 49E-04 O.OOE+OO 4. 49E-04 

8.00E+Ol 4. 49E-04 O.OOE+OO 4.49E-04 

9.00E+Ol 4. 49E-04 O.OOE+OO 4. 49E-04 

1.00E+02 4. 49E-04 O.OOE+OO 4. 49E-04 

2.00E+02 4. 47E-04 O.OOE+OO 4. 47E-04 

3.00E+02 4.46E-04 O.OOE+OO 4. 46E-04 

4.00E+02 4.44E-04 O.OOE+OO 4. 44E-04 

5.00E+02 4. 43E-04 O.OOE+OO 4. 43E-04 

6.00E+02 4.41E-04 O.OOE+OO 4.41E-04 

7.00E+02 4.40E-04 O.OOE+OO 4.40E-04 

8.00E+02 4. 38E-04 O.OOE+OO 4. 38E-04 

9.00E+02 4. 37E-04 O.OOE+OO 4. 37E-04 .. 1.00E+03 4. 35E-04 O.OOE+OO 4.35E-04 

2.00E+03 4.2lE-04 O.OOE+OO 4.2lE-04 

3.00E+03 4.08E-04 O.OOE+OO 4.08E-04 

4.00E+03 3. 94E-04 O.OOE+OO 3. 94E-04 

5.00E+03 3. 82E-04 O.OOE+OO 3. 82E-04 

6.00E+03 3.70E-04 O.OOE+OO 3.70E-04 

7.00E+03 3.58E-04 O.OOE+OO 3. 58E-04 

8.00E+03 3. 47E-04 O.OOE+OO 3. 47E-04 

9.00E+03 3.36E-04 O.OOE+OO 3. 36E-04 

1.00E+04 3. 25E-04 O.OOE+OO 3. 25E-04 

2.00E+04 2.40E-04 O.OOE+OO 2.40E-04 

B-702 
INGIS'l'IOR fl- 5.00£-04 IlA.I.FUPE- 2.69£+06 DAYS AMERICIUM 243 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-OI 1.S8E-06 6.10E-04 

2.00E-Ol 6. 84E-06 S.90E-03 

3.00E-Ol 1. 37E-OS 1.94E-02 

4.00E-Ol 2.0SE-OS 4.16E-02 

S.OOE-Ol 2.6SE-OS 7.18E-02 

6.00E-Ol 3.1SE-OS 1.OSE-Ol 

7.00E-Ol 3.S6E-OS 1.49E-Ol 

8.00E-Ol 3. 89E-OS 1. 94E-Ol 

9.00E-Ol 4.14E-OS 2.40E-Ol 

1.OOE+OO 4. 34E-OS 4. 34E-OS 2. 86E-Ol 2.S6E-Ol 

2.00E+OO 6.02E-06 4. 94E-OS 3.90E-Ol 6. 76E-Ol 

3.00E+OO 4.00E-07 4.9SE-OS 1.9SE-Ol S.71E-Ol 

4.00E+OO 3. 9 IE-OS 4. 99E-05 7.98E-02 9.51E-Ol 

S.OOE+OO 1.6SE-08 4. 99E-05 3.06E-02 9'.81E-Ol 

6.00E+OO 1.50E-08 4. 99E-OS l.lSE-02 9. 93E-Ol 

7.00E+OO 1.50E-08 4. 99E-OS 4. 25E-03 9. 97E-Ol 

8.00E+OO 1. 49E-OS 4. 99E-OS 1.57E-03 9. 99E-Ol 

9.00E+OO 1. 49E-08 5.00E-OS 5. 78E-04 9. 99E-Ol 

1.OOE+Ol 1. 49E-08 5.00E-OS 2. 13E-04 9. 99E-Ol 

2.00E+Ol 1. 49E-08 5.01E-05 O.OOE+OO 9. 99E-Ol 

3.00E+Ol 1.49E-08 5.03E-05 O.OOE+OO 9. 99E-Ol 

4.00E+Ol 1. 49E-08 5.04E-05 O.OOE+OO 9. 99E-Ol 

S.OOE+Ol 1.49E-08 5.06E-05 O.OOE+OO 9. 99E-Ol 

6.00E+Ol 1. 49E-08 5.07E-05 O.OOE+OO 9. 99E-Ol 

7.00E+Ol 1. 49E-08 S.09E-05 O.OOE+OO 9. 99E-Ol 

8.00E+Ol 1. 49E-08 S.lOE-05 O.OOE+OO 9.99E-Ol 

9.00E+Ol 1. 49E-OS S.I2E-05 O.OOE+OO 9. 99E-OI 

1.OOE+02 1. 49E-08 S.13E-oS O.OOE+OO 9.99E-Ol 

2.00E+02 1. 48E-08 S.28E-05 O.OOE+OO 9. 99E-OI 

3.00E+02 1. 48E-08 S.43E-05 O.OOE+OO 9. 99E-OI 

4.00E+02 1.47E-08 5.S8E-05 O.OOE+OO 9. 99E-OI 

S.OOE+02 1. 47E-08 S.72E-05 O.OOE+OO 9. 99E-OI 

6.00E+02 1. 46E-08 S.87E-OS O.OOE+OO 9. 99E-OI 

7.00E+02 1.4SE-08 6.01E-OS O.OOE+OO 9. 99E-OI 

8.00E+02 1. 45E-08 " 6.16E-OS O.OOE+OO 9. 99E-OI 

9.00E+02 1. 44E-08 6.30E-OS O.OOE+OO 9. 99E-Ol 

1.OOE+03 1. 44E-08 6.4SE-OS O.OOE+OO 9.99E-OI 

2.00E+03 1. 38E-08 7.8SE-OS O.OOE+OO 9. 99E-Ol 

3.00E+03 1. 33E-08 9.2IE-05 O.OOE+OO 9.99E-OI 

4.00E+03 1. 28E-08 1.05E-04 O.OOE+OO 9. 98E-Ol 

5.00E+03 I.23E-08 I.18E-04 O.OOE+OO 9.9SE-OI 

7.00E+03 I.I4E-08 I.4IE-04 O.OOE+OO 9.9SE-OI 

8.00E+03 1. IOE-08 I.52E-04 O.OOE+OO 9.97E-OI 

9.00E+03 I.OSE-08 1. 63E-04 O.OOE+OO 9.97E-OI 

1.OOE+04 I.02E-08 I.73E-04 O.OOE+OO 9. 97E-Ol 

B-703 
JRGBSTIOH fl- 5.00£-04 IIALFLlFE- 1.63£+02 DAYS CURIUM 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE --~----------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.OOE-Ol 1.48E-04 9. 99E-Ol 9. 99E-Ol 

2.00E-Ol 2. 94E-04 9. 93E-Ol 9. 93E-Ol 

3.00E-Ol 3.76E-04 9.79E-Ol 9. 79E-Ol 

4.00E-Ol 4.18E-04 9. 56E-Ol 9.S7E-Ol 

5.00E-Ol 4. 39E-04 9. 26E-Ol 9. 26E-Ol 

6.00E-Ol 4. 49E-04 8.89E-Ol 8.89E-Ol 

7.00E-Ol 4.S3E-04 8. 48E-0l 8. 48E-Ol 

8.00E-Ol 4. 54E-04 8.03E-Ol 8.04E-Ol 

9.00E-Ol 4. S4E-04 7.57E-Ol 7.S7E-Ol 

1.OOE+OO 4.S3E-04 7.10E-Ol 7.lOE-ol 

2.00E+OO 4. 47E-04 3.21E-Ol 3.21E-Ol 

3.00E+OO 4. 44E-04 1. 27E-Ol 1.27E-Ol 

4.00E+OO 4. 43E-04 4.80E-02 4. 85E-02 

5.00E+OO 4.41E-04 1. 78E-02 1. 83E-02 

6.00E+OO 4. 39E-04 6. 57E-03 7.01E-03 

7.00E+OO 4. 37E-04 2.41E-03 2.8SE-03 

8.00E+OO 4.35E-04 8. 85E-04 1. 32E-03 

9.00E+OO 4. 33E-04 3. 24E-04 7.S7E-04 

1.OOE+Ol 4.31E-04 1.19E-04 5.50E-04 

2.00E+Ol 4.13E-04 O.OOE+OO 4.13E-04 

3.00E+Ol 3. 96E-04 O.OOE+OO 3. 96E-04 

4.00E+Ol 3. 79E-04 O.OOE+OO 3. 79E-04 

5.00E+Ol 3. 63E-04 O.OOE+OO 3. 63E-04 

6.00E+Ol 3. 48E-04 O.OOE+OO 3. 48E-04 

7.00E+Ol 3. 33E-04 O.OOE+OO 3. 33E-04 

8.00E+Ol 3.19E-04 O.OOE+OO 3.19E-04 

9.00E+Ol 3.06E-04 O.OOE+OO 3.06E-04 

1.OOE+02 2. 93E-04 O.OOE+OO 2. 93E-04 

2.00E+02 1.91E-04 O.OOE+OO 1.91E-04 

3.00E+02 1. 24E-04 O.OOE+OO 1. 24E-04 

4.00E+02 S.09E-05 O.OOE+OO 8.09E-OS 

5.00E+02 S.27E-OS O.OOE+OO S.27E-OS 

6.00E+02 3. 43E-05 O.OOE+OO 3. 43E-05 

7.00E+02 2. 23E-05 O.OOE+OO 2. 23E-OS 

8.00E+02 1. 45E-OS O.OOE+OO 1. 45E-05 

9.00E+02 9. 47E-06 O.OOE+OO 9. 47E-06 

1.OOE+03 6.16E-06 O.OOE+OO 6.16E-06 

2.00E+03 8. 44E-08 O.OOE+OO 8. 44E-08 

B-704 
IHCESTIOR f 1- S.001-o4 IflLI'LlPE- 1.63B+o2 DAYS ClJIUUH 242 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------ SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- Z4-HOUR ACCUMULATED Z4-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-0i 1.5SE-06 6.09E-04 

Z.OOE-Ol 6.S4E-06 S.90E-03 

3.00E-Ol 1. 37E-OS 1.93E-OZ 

4.00E-Ol 2.04E-05 4.l5E-02 

S.OOE-Ol 2. 64E-05 7.l6E-02 

6.00E-Ol 3.15E-OS 1.OSE-Ot 

7.00E-OI 3.S5E-05 1. 49E-OI 

S.OOE-Ol 3. SSE-OS 1. 93E-Ol 

9.00E-Ol 4.13E-05 2. 39E-Ol 

1.OOE+OO 4. 32E-OS 4. 32E-05 2.S5E-Ol 2.S5E-Ol 

2.00E+OO 5. 97E-06 4.90E-05 3. S6E-Ol 6.70E-Ol 

3.00E+OO 3. 94E-07 4. 92E-05 I. 92E-OI S.60E-Ol 

4.00E+OO 3.S4E-OS 4.90E-05 7. S5E-02 9. 35E-OI 

5.00E+OO 1.6IE-OS 4. 88E-05 3.00E-02 9.6IE-OI 

6.00E+OO 1. 47E-OS 4.S7E-05 l.lZE-02 9.6SE-OI 

7.00E+OO I. 45E-OS 4.S5E-05 4.13E-03 9.6SE-OI 

S.OOE+OO I. 44E-OS 4.S3E-05 1.52E-03 9. 65E-OI 

9.00E+OO 1. 44E-OS 4.SlE-05 5. 57E-04 9. 62E-OI 

1.OOE+Ol 1.43E-OS 4. 79E-05 2.04E-04 9.5SE-Ol 

2.00E+Ol 1. 37E-OS 4.60E-05 O.OOE+OO 9.lSE-OI 

3.00E+Ol 1.3IE-OS 4. 42E-;o05 O.OOE+OO S.SOE-Ol 

4.00E+Ol 1. 26E-OS 4. 25E-05 O.OOE+OO S.43E-OI 

5.00E+OI 1.2lE-OS 4.09E-05 O.OOE+OO S.OSE-Ol 

6.00E+Ol 1.16E-OS 3. 93E-05 O.OOE+OO 7. 74E-OI 

7.00E+OI I. liE-OS 3.7SE-05 O.OOE+OO 7.42E-Ol 

S.OOE+Ol 1.06E-OS 3. 63E-05 O.OOE+OO 7.11E-Ol 

9.00E+Ol 1.02E-OS 3. 49E-05 O.OOE+OO 6.SIE-Ol 

B-705 
INGESTION fl= 5.00£-04 HALFLIFE- 6.61£+03 DAYS CORIUM 244 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE -------------------------------------------------------- SYSTEMIC GI TOTAL 

DAYS ORGANS TRACT BODY 

1.00E-Ol 1. 48E-04 9.99E-Ol 9. 99E-Ol 

2.00E-Ol 2. 94E-04 9. 94E-Ol 9.94E-Ol 

3.00E-Ol 3.76E-04 9.80E-Ol 9.81E-Ol 

4.00E-Ol 4. 19E-04 9.58E-Ol 9. 58E-Ol 

5.00E-Ol 4.40E-04 9.28E-Ol 9.28E-Ol 

6.00E-Ol 4.50E-04 8.91E-Ol 8.92E-Ol 

7.00E-Ol 4. 54E-04 8.50E-Ol 8. 51E-Ol 

8.00E-Ol 4. 56E-04 8.06E-Ol 8.06E-01 

9.00E-Ol 4. 56E-04 7.60E-01 7.60E-Ol 

1.00E+00 4. 55E-04 7. 13E-Ol 7. 13E-01 

2.00E+00 4.50E-04 3.23E-Ol 3.24E-Ol 

3.00E+00 4.50E-04 1. 29E-01 1. 29E-Ol 

4.00E+00 4.50E-04 4. 88E-02 4. 93E-02 

5.00E+00 4.50E-04 1. 82E-02 1. 87E-02 

6.00E+00 4.50E-04 6. 74E-03 7. 18E-03 

7.00E+00 4.50E-04 2. 48E-03 2. 93E-03 

8.00E+00 4.50E-04 9. 14E-04 1.36E-03 

9.00E+00 4.50E-04 3. 37E-04 7.86E-04 

1.00E+01 4.50E-04 1. 24E-04 5. 73E-04 

2.00E+Ol 4. 49E-04 O.OOE+OO 4.49E-04 

3.00E+Ol 4. 48E-04 O.OOE+OO 4. 48E-04 

4.00E+01 4. 48E-04 O.OOE+OO 4. 48E-04 

5.00E+Ol 4'. 47E-04 ,O.OOE+OO 4. 47E-04 

6.00E+Ol 4. 46E-04 O.OOE+OO 4. 46E-04 

7.00E+Ol 4. 46E-04 O.OOE+OO 4.46E-04 

8.00E+01 4. 45E-04 O.OOE+OO 4. 45E-04 

9.00E+01 4. 45E-04 O.OOE+OO 4.45E-04 

1.00E+02 4. 44E-04 O.OOE+OO 4. 44E-04 

2.00E+02 4. 38E-04 O.OOE+OO 4. 38E-04 

3.00E+02 4. 32E-04 O.OOE+OO 4. 32E-04 

4.00E+02 4.26E-04 O.OOE+OO 4. 26E-04 

5.00E+02 4.20E-04 O.OOE+OO 4.20E-04 

6.00E+02 4. 14E-04 O.OOE+OO 4. 14E-04 

7.00E+02 4.09E-04 O.OOE+OO 4.09E-04 

8.00E+02 4.03E-04 O.OOE+OO 4.03E-04 

9.00E+02 3. 98E-04 O.OOE+OO 3. 98E-04 

1.00E+03 3. 92E-04 O.OOE+OO 3. 92E-04 

2.00E+03 3. 42E-04 O.OOE+OO 3. 42E-04 

3.00E+03 2. 98E-04 O.OOE+OO 2. 98E-04 

4.00E+03 2.60E-04 O.OOE+OO 2.60E":"04 

5.00E+03 2. 26E-04 O.OOE+OO 2. 26E-04 

6.00E+03 1.97E-04 O.OOE+OO 1. 97E-04 

7.00E+03 1. 72E-04 O.OOE+OO 1.72E-04 

8.00E+03 1.50E-04 O.OOE+OO 1.50E-04 

9.00E+03 1. 31E-04 O.OOE+OO 1.31E-04 

1.00E+04 1. 14E-04 O.OOE+OO 1.1-4E-04 

2.00E+04 2. 96E-05 O.OOE+OO 2. 96E-05 

B-706 
INGESTION f1= 5.00E-04 BALFLIFE= 6.61E+03 DAYS CURIUM 244 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ------------------------------------------------------

SYSTEMIC NON-SYSTEMIC 

------------------------- ----------------------- 24-HOUR ACCUMULATED 24-HOUR ACCUMULATED 

DAYS EXCRETA EXCRETA FECES FECES 

1.OOE-Ol 1.58E-06 6.10E-04 

2.00E-Ol 6.84E-06 5.90E-03 

3.00E-0l 1. 37E-OS 1.94E-02 

4.00E-01 2.04E-OS 4.16E-02 

5.00E-01 2.65E-OS 7.18E-02 

6.00E-Ol 3. 15E-OS 1.08E-Ol 

7.00E-Ol 3. S6E-OS 1.49E-01 

8.00E-01 3. 89E-OS 1. 94E-Ol 

9.00E-01 4. 14E-OS 2.40E-01 

1.00E+OO 4. 34E-05 4. 34E-05 2. 86E-Ol 2.86E-01 

2.00E+OO 6.02E-06 4.94E-OS 3.89E-01 6.76E-01 

3.00E+OO 3. 99E-07 4.98E-05 1.95E-Ol 8.7lE-Ol 

4.00E+OO 3.91E-08 4.99E-OS 7.98E-02 9.S0E-01 

S.OOE+OO 1.6SE-08 4. 99E-05 3.06E-02 9.8lE-Ol 

6.00E+OO 1.50E-08 4. 99E-05 1. 15E-02 9. 92E-Ol 

I 7.00E+OO 1.49E-08 4.99E-OS 4. 25E-03 9. 96E-Ol 

8.00E+OO 1.49E-08 4.99E-05 1. S7E-03 9.98E-Ol 

9.00E+OO 1~49E-08 4. 99E-OS 5. 78E-04 9. 98E-Ol 

1.00E+01 1.49E-08 4.99E-05 2.l3E-04 9.98E-Ol 

2.00E+Ol 1.49E-08 S.00E-05 O.OOE+OO 9.97E-Ol 

3.00E+Ol 1.49E-08 5.0lE-05 O.OOE+OO 9.96E-Ol 

4.00E+Ol 1.49E-08 S.02E-05 O.OOE+OO 9.9SE-01 

S.OOE+Ol 1.48E-08 5.03E-05 O.OOE+OO 9.94E-Ol 

6.00E+01 1. 48E-08 S.04E-05 O.OOE+OO 9.93E-01 

7.00E+01 1.48E-08 S.OSE-05 O.OOE+OO 9. 92E-01 

8.00E+01 1.48E-08 S.06E-OS O.OOE+OO 9.91E-Ol 

9.00E+01 1.48E-08 S.07E-OS O.OOE+OO 9.90E-01 

1.00E+02 1.47E-08 S.08E-OS O.OOE+OO 9.89E-Ol 

2.00E+02 1.4SE-08 S.17E-OS O.OOE+OO 9.79E-Ol 

3.00E+02 1.431<.:-08 S.26E-OS O.OOE+OO 9.69E-01 

4.00E+02 1.41E-08 S.3SE-OS O.OOE+OO 9. S8E-Ol 

S.OOE+02 1. 39E-08 S.43E-OS O.OOE+OO 9.48E-Ol 

6.00E+02 1.37E-08 S.5lE-OS O.OOE+OO 9. 39E-Ol 

7.00E+02 1.3SE-08 S.S9E-05 O.OOE+OO 9.29E-Ol 

8.00E+02 1. 33E-08 S.66E-05 O.OOE+OO 9.l9E-01 

. 9.00E+02 1.31E-08 5.74E-05 O.OOE+OO 9.09E-Ol 

1.00E+03 1.29E-08 5.81E-05 O.OOE+OO 9.00E-Ol 

2.00E+03 1.12E-08 6.37E-05 O.OOE+OO 8.lOE-Ol 

B-707 

BOl-a 

1IJl0dYA 110 1JlIJ.VIl (-B <DIV c3«1XOROR fJ'1-a 

c 3«1XOI0 'II-a .10 mIV.T.NI 3."I!)R1S 1I0i1 ROIJ.31I:»X3 <DIV ROIJ.R3J.3lI 110.1 snllVJ. ·9 
fl ... 1.0 GAS (14 CO2

) BALFLlFE • 2.09E+06 DAYS CARBON 14 DIOXIDE 

TI~ AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ---------------------------------------------------

TOTAL 24-HOUR ACCUMULATED 

DAYS BODY EXCRETA EXCRETA 

1.00E-Ol 9. 98E-03 9.90E-Ol 

2.00E-Ol 9. 97E-03 9.90E-Ol 

3.00E-01 9. 95E-03 9.90E-Ol 

4.00E-Ol 9. 93E-03 9.90E-Ol 

5.00E-Ol 9. 92E-03 9.90E-Ol 

6.00E-Ol 9.90E-03 9.90E-Ol 

7.00E-Ol 9. 88E-03 9.90E-Ol 

8.00E-Ol 9. 87E-03 9.90E-Ol 

9.00E-Ol 9.85E-03 9.90E-Ol 

1.00E+00 9. 84E-03 1. 64E-04 9.90E-Ol 

2.00E+00 9. 67E-03 1.61E-04 9.90E-Ol 

3.00E+00 9. 51E-03 1. 58E-04 9.90E-Ol 

4.00E+00 9. 36E-03 1.56E-04 9.91E-Ol 

5.00E+00 9.20E-03 1. 53E-04 9.91E-Ol 

6.00E+00 9.05E-03 1. 51E-04 9.91E-Ol 

7.00E+00 8.90E-03 1. 48E-04 9.91E-Ol 

8.00E+00 8. 75E-03 1.46E-04 9.91E-Ol 

9.00E+00 8.61E-03 1. 43E-04 9.91E-Ol 

1.00E+Ol 8. 47E-03 1.41E-04 9. 92E-Ol 

2.00E+Ol 7.17E-03 1. 19E-04 9. 93E-Ol 

3.00E+Ol 6.07E-03 1.01E-04 9. 94E-Ol 

4.00E+Ol 5. 14E-03 8. 55E-05 9. 95E-Ol 

5.00E+Ol 4. 35E-03 7. 24E-05 9. 96E-Ol 

6.00E+Ol 3. 69E-03 6. 13E-05 9. 96E-Ol 

7.00E+01 3. 12E-03 5. 19E-05 9. 97E-Ol 

8.00E+Ol 2. 64E-03 4.40E-05 9.97E-Ol 

9.00E+Ol 2. 24E-03 3.72E-05 9. 98E-Ol 

1.00E+02 1.90E-03 3. 15E-05 9. 98E-Ol 

2.00E+02 3. 59E-04 5. 98E-06 1.00E+00 

3.00E+02 6. 81E-05 1. 13E-06 1.00E+00 

4.00E+02 1.29E-05 2. 15E-07 1.00E+00 

B-709 
fl = 1.0 GAS (14 CO) HALFLlFE = 2.09E+06 DAYS CARBON 14 MONOXIDE 

TIME AFTER FRACTION OF INITIAL INTAKE IN: 

S INGLE INTAKE ---------------------------------------------------

TOTAL 24-HOUR ACCUMULATED 

DAYS BODY EXCRETA EXCRETA 

1.OOE-0l 2. 43E-Ol 7. 57E-Ol 

2.00E-Ol 1. 48E-Ol 8. 52E-Ol 

3.00E-Ol 8. 96E-02 9.lOE-Ol 

4.00E-Ol S.44E-02 9.46E-Ol 

S.OOE-Ol 3.31E-02 9.67E~01 

6.00E-Ol 2.01E-02 9.80E-Ol 

7.00E-Ol 1. 22E-02 9. 88E-Ol 

8.00E-Ol 7.41E-03 9.93E-Ol 

9.00E-Ol 4.50E-03 9. 96E-Ol 

1.OOE+OO 2. 73E-03 1. 36E-02 9.97E-Ol 

2.00E+OO 1. 87E-05 9.31E-05 1.OOE+OO 

3.00E+OO 1. 28E-07 6. 36E-07 1.OOE+OO 

B-710 
fl - 1.0 VAPOR OR LIQUID (lu2o) IlALFLIFE - 4.49B+03 DAYS BYDROGBN 3 

TI~ AFTER FRACTION OF INITIAL INTAKE IN: 

SINGLE INTAKE ----------------------------------------------------

TO'fAL 24-HOUR ACCUMULATED 

DAYS BODY URINE URINE 

1.00E-Ol 9.93E-01 4. 19E-03 

2.00E-Ol 9. 86E-Ol 8. 34E-03 

3.00E-Ol 9.79E-ol 1.25E-02 

4.00E-Ol 9.72E-Ol 1. 66E-02 

5.00E-01 9. 66E-01 2.06E-02 

6.00E-Ol 9. 59E-Ol 2. 47E-02 

7.00E-Ol 9. 52E-01 2. 87E-02 

8.00E-Ol 9.46E-Ol 3. 27E-02 

9.00E-Ol 9. 39E-01 3. 66E-02 

1.00E+00 9. 36E-Ol 3. 85E-02 3. 85E-02 

2.00E+00 8.73E-Ol 3.76E-02 7.61E-02 

3.00E+00 8. 14E-Ol 3. 51E-02 1. 11E-01 

4.00E+00 7.60E-01 3.27E-02 1.44E-Ol 

5.00E+00 7.09E-Ol 3.05E-02 1. 74E-Ol 

6.00E+00 6.61E-Ol 2. 85E-02 2.03E-01 

7.00E+00 6. 17E-01 2. 66E-02 2.29E-Ol 

8.00E+00 5.75E-Ol 2.48E-02 2.54E-Ol 

9.00E+00 5.37E-01 2. 31E-02 2.77E-01 

1.00E+01 5.01E-01 2. 16E-02 2.99E-01 

2.00E+Ol 2.50E-Ol 1.08E-02 4.48E-01 

3.00E+01 1.25E-01 5. 37E-03 5.22E-01 

4.00E+01 6.23E-02 2. 68E-03 5.59E-ol 

5.00E+01 3.11E-02 1. 34E-03 5. 77E-01 

6.00E+01 1.55E-02 6.69E-04 5.85E-01 

7.00E+01 7.76E-03 3.34E-04 5. 89E-01 

8.00E+01 3. 87E-03 1. 67E-04 5.90E-Ol 

9.00E+01 1.93E-03 8.33E-05 5.91E-01 

1.00&+02 9. 66E-04 4. 16E-05 5.90E-01 

2.00E+02 9.30E-07 4.01E-08 5.89E-01 

B-711 

ZIl-a: 

.xan.ts SIB.t HI aUB mm.t3H.V'8.Vd' Tr.)IOO'lOIUW mIY 'IV:>IOO'IOItI • L 
ELEMENT DATA SHEET 

ELEMENT: HYDROGEN 

PHYSICAL STATE: VAPOUR OR LIQUID, HTO or T20 

LUNG DEPOSITION: 1.0 

SYSTEMIC UPTAKE: 1.0 

SYSTEMIC RETENTION: 

COEFFICIENT 

1.00E+00 

RATE CONSTANT, 

I/DAYS 

6. 93E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 1.00E+00 INGESTION 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 6.00E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): NO DATA 

THE COMMON ISOTOPES OF HYDROGEN: MASS NUMBER 

3 

1 

B-713 

HALFLlFE, DAYS 

4. 51E+03 

STABLE 
ELEMENT DATA SHEET 

ELEMENT: BERYLLIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.40E-01 

1.60E-01 

4.00E-01 

FRACTION FROM GI TRACT TO BLOOD (£1): 5.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

1!DAYS 

4. 62E-04 

4. 62E-02 

2. 77E+OO 

O.OOE+OO CLASS D 5.00E-03 CLASS W 5.00E-03 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF BERYLLIUM: MASS NUMBER 

7 

9 

10 

B-714 

HALFLIFE, DAYS 

5. 33E+01 

STABLE 

5. 84E+08 
.', .' ' 

ELEMENT DATA SHEET 

ELEMENT: CARBON 

PHYSICAL STATE: GAS. MONOXIDE 

LUNG DEPOSITION: 1.0 

SYSTEMIC UPTAKE: 1.0 

SYSTEMIC RETENTION: 

EXCRETION PATHWAYS ARE NOT DEFINED 

THE COMMON ISOTOPES OF CARBON: 

COEFFICIENT 

6.00E-Ol 

4.00E-Ol 

MASS NUMBER 

11 

14 

12 

B-715 

RATE CONSTANT, 

l!DAYS 

1. 39E-Ol 

1.00E+07 

ItALFLIFE, DAYS 

1.41E-02 

2.09E+06 

STABLE 
ELEMENT DATA SHEET 

ELEMENT: CARBON 

PHYSICAL STATE: GAS, DIOXIDE 

LUNG DEPOSITION: 1.0 

SYSTEMIC UPTAKE: 1.0 

SYSTEMIC RETENTION: 

EXCRETION PATHWAYS ARE NOT DEFINED 

THE COMMON ISOTOPES OF CARBON: 

COEFFICIENT 

1.80E-Ol 

8.lOE-Ol 

1.00E-03 

MASS NUMBER 

11 

14 

12 

B-716 

RATE CONSTANT, 

l/DAYS 

2.00E+02 

1. 66E+Ol 

1. 66E-02 

HALFLIFE, DAYS 

1.41E-02 

2.09E+06 

STABLE 
ELEMENT DATA SHEET 

ELEMENT: FLUORINE 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

O.OOE-OO 

FRACTION FROM GI TRACT TO BLOOD (£1): 1.00E+OO INGESTION 

1.00E+OO CLASS D 1.00E+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED 

THE COMMON ISOTOPES OF FLUORINE: 

-------------------------------

1.00E+OO CLASS Y 

MASS NUMBER 

18 

19 

B-717 

HALFLIFE, DAYS 

7. 62E-02 

STABLE 
ELEMENT DATA SHEET 

ELEMENT: SODIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

l.OOE+OO CLASS D O.OOE+OO CLASS W 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2. 97E-Ol 

3.00E-03 

7.00E-Ol 

l.OOE+OO INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

6. 93E-02 

l.39E-03 

6. 93E-02 

O.OOE+OOCLASS Y 

FRACTION OF SYSTEMIC BURDEN EXCRETED THROUGH URINE (fu ): "'1.0E+OO 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): l.OE-02 

THE COMMON ISOTOPES OF SODIUM: MASS NUMBER 

22 

23 

24 

B-718 

HALFLIFE, DAYS 

9.50E+02 

STABLE 

6. 25E-Ol 
ELEMENT DATA SHEET 

ELEMENT: MAGNESIUM 

PARTICLE SIZE: l.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.l0E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2.00E-Ol 

8.00E-Ol 

5.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

2.77E+OO 

6. 93E-03 

5.00E-Ol CLASS D 5.00E-Ol CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED 

THE COMMON ISOTOPES OF MAGNESIUM: MASS NUMBER 

24 

28 

B-7l9 

RALFLIFE, DAYS 

STABLE 

8.71E-Ol 
ELEMENT DATA SHEET 

ELEMENT: ALUMINUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-0l 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

6. 93E-03 

FRACTION FROM GI TRACT TO BLOOD (£1): 1.00E-02 INGESTION 

1.00E-02 CLASS D 1.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED 

THE COMMON ISOTOPES OF ALUMINUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

26 

27 

HALFLIFE, DAYS 

2. 61E+08 

STABLE 

B-720 
ELEMENT DATA SHEET 

ELEMENT: SILICON 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1) : 

1.00E-02 CLASS D 1.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.00E-01 

6.00E-01 

1.00E-02 INGESTION 

1.00E-02 CLASS Y 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

1/DAYS 

1. 39E-Ol 

6. 93E-03 

THE COMMON ISOTOPES OF SILICON: MASS NUMBER HALFLIFE, DAYS 

28 

31 

32 

B-721 

STABLE 

1.09E-01 

1. 64E+05 
ELEMENT DATA SHEET 

ELEMENT: PHOSPHORUS 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.50E-Ol 

1.50E-Ol 

4.00E-01 

3.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

1. 39E+00 

3. 47E-Ol 

3. 65E-02 

4. 62E-04 

FRACTION FROM GI TRACT TO BLOOD (f 1): 8.00E-Ol INGESTION 

8.00E-Ol CLASS D 8.00E-01 CLASS W O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 9.00E-01 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 1.00E-Ol 

THE COMMON ISOTOPES OF PHOSPHORUS: MASS NUMBER 

31 

32 

33 

8-722 

HALFLIFE, DAYS 

STABLE 

1. 43E+Ol 

2. 54E+Ol 
ELEMENT DATA SHEET 

ELEMENT: SULPHUR 

PARTICLE SIZE: l.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3. lOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1. SOE-Ol 

S.OOE-02 

8.00E-Ol 

PULMONARY 

PARENCHYMA 

2.49E-OI 

RATE CONSTANT, 

I!DAYS 

3.47E-02 

3.47E-04 

2.77E+OO 

FRACTION FROM GI TRACT TO BLOOD (f 1): 8.00E-Ol INGESTION 

8.00E-Ol CLASS D 8.00E-Ol CLASS W O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 9.00E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 1.OOE-Ol 

THE COMMON ISOTOPES OF SULPHUR: MASS NUMBER 

32 

3S 

B-723 

HALFLIFE) DAYS 

STABLE 

8.74E+Ol 
.-:, 

ELEMENT DATA SHEET 

ELEMENT: CHLORINE 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- ,PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

1.00E+OO CLASS D 1.00E+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF CHLORINE: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

1.00E+OO INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

6. 93E-02 

O.OOE+OO CLASS Y 

MASS NUMBER 

35 

36 

38 

39 

HALFLIFE, DAYS 

STABLE 

1.10E+08 

2. 58E-02 

3. 86E-02 

B-724 
ELEMENT DATA SHEET 

ELEMENT: POTASSIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEHIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

1.00E+OO INGESTION 

PULHONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

IjDAYS 

2.30E-02 

1.00E+00 CLASS D O.OOE+OO CLASS W O.OOE+OO CLASS Y 

EXCRETION .PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF POTASSIUM: HASS NUMBER 

39 

40 

42 

43 

44 

45 

B-725 

HALFLIFE, DAYS 

STABLE 

4.67E+ll 

5.15E-Ol 

9.42E-Ol 

1.54E-02 

1.39E-02 
ELEMENT DATA SHEET 

ELEMENT: CALCIUM 

PARTICLE SIZE: 1.0E+OO ~lICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

O.OOE+OO CLASS D 3.00E-Ol CLASS W 

TRACHEA AND PULMONARY 

BRONCHIAL TREE PARENCHYMA 

8.00E-02 

COEFFICIENT 

3.S6E-02 

3.14E-03 

4. 31E-Ol 

9.00E-02 

7.02E-02 

1.29E-0l 

2.41E-Ol 

3.00E-Ol INGESTION 

2.49E-Ol 

RATE CONSTANT, 

I!DAYS 

2.46E+Ol 

1.21E+OO 

8.80E-02 

6. 86E-03 

1.90E-03 

3.70E-04 

7. 86E-05 

O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 5.00E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 5.00E-Ol 

THE COMMON ISOTOPES OF CALCIUM: MASS NUMBER 

40 

41 

45 

47 

B-726 

HALFLIFE, DAYS 

STABLE 

5.11E+07 

1. 63E+02 

4. 53E+OO 
ELEMENT DATA SHEET 

ELEMENT: SCANDIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

------------------------------------

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-01 

9.00E-0l 

1.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-01 

RATE CONSTANT, 

1!DAYS 

1.39E-01 

4. 62E-04 

O.OOE+OO CLASS D O.OOE+OO CLASS W 1.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF SCANDIUM: MASS NUMBER 

43 

44 

44m 

45 

46 

47 

48 

49 

B-727 

HALFLIFE, DAYS 

1. 62E-01 

1. 64E-01 

2. 44E+OO 

STABLE 

8. 38E+01 

3. 35E+OO 

1.82E+OO 

3. 98E-02 
ELEMENT DATA SHEET 

ELEMENT: TITANIUM 

PARTICLE SIZE: I.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (fI ): 

1.OOE-02 CLASSD I.OOE-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TITANIUM: 

--------------------~--------~ 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.OOE+OO 

I.OOE-02 INGESTION 

PULMONARY 

PARENCHYMA 

<2. 49E-OI 

RATE CONSTANT, 

I/DAYS 

1.I6E-03 

I.OOE-02 CLASS Y 

ItfASS NUMBER 

44 

45 

48 

HALFLIFE, 

1. 73E-02 

1. 28E-OI 

STABLE 

B-728 
ELEMENT DATA SHEET 

ELEMENT: VANADIuM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3. 1 OE-O 1 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

---------~--------------------------

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.00E-Ol 

3.00E-0l· 

1.OOE-02 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

2.77E+OO 

6.93E-05 

1.00E-02 CLASS D 1.00E-02 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF VANADIUM: MASS NUMBER 

47 

48 

49 

51 

B-729 

HALFLIFE, DAYS 

2. 26E-02 

1.62E+Ol 

3.30E+02 

STABLE 
ELEMENT DATA SHEET 

ELEMENT: CHROMIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.IOE-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

1.00E-Ol CLASS D 1.00E-Ol CLASSW 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF CHRO~IIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-02 

4.00E-Ol 

2.50E-Ol 

3.00E-Ol 

1.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

6. 93E-04 

1. 16E-Ol 

8. 66E-03 

1. 39E+00 

1.00E-01 CLASS Y 

MASS NUMBER 

48 

49 

51 

52 

HALFLlFE, DAYS 

9. 57E-Ol 

2. 92E-02 

2.77E+Ol 

STABLE 

B-730 
ELEMENT DATA SHEET 

ELEMENT: MANGANESE 

PARTICLE SIZE: I.OE+OO MICRONS _ ...... _-----_ .... 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (fl ): 

-----~----------------------~----

I.OOE-OI CLASS D I.OOE-OI CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF MANGANESE: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.00E-OI 

3.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-OI 

RATE CONSTANT; 

I/DAYS 

I.73E-02 

1. 73E-Ol 

I.OOE-OI INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

51 

52 

52M 

53 

54 

55 

56 

HALFLIFE, DAYS 

3.21E-02 

5. 59E+OO 

I.47E-02 

1. 35E+09 

3.13E+02 

STABLE 

I.07E-OI 

B-731 
ELEMENT DATA SHEET 

ELEMENT: IRON 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

3. 47E-04 

FRACTION FROM GI TRACT TO BLOOD {tIl: 1.00E-01 INGESTION 

1.00E-Ol CLASS D 1.00E-01 CLASS W 

EXCRETION PATHWAYS ARE .NOT DEFINED: 

THE COMMON ISOTOPES OF IRON: 

O.OOE+OO CLASS Y 

MASS N(J}oIBER 

52 

55 

56 

59 

60 

HALFLIFE, DAYS 

3. 45E-Ol 

9. 86E+02 

STABLE 

4. 45E+Ol 

3. 65E+07 

B-732 
ELEHENT DATA SHEET 

ELEMENT: COBALT 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-Ol 

3.00E-Ol 

1.00E-0l 

1.00E-0l 

FRACTION FROM GI TRACT TO BLOOD (f 1): 5.00E-02 INGESTION 

-------------------~---------------

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I!DAYS 

1. 39E+00 

1. 16E-Ol 

1. 16E-02 

8.66E-04 

O.OOE+OO CLASS D 5.00E-02 CLASS W 5.00E-02 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 8.00E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 2.00E-Ol 

THE COMMON ISOTOPES OF COBALT: MASS NUMBER 

55 

56 

57 

58 

58m 

59 

60 

60m 

61 

B-733 

HALFLIFE,DAYS 

7.30E-Ol 

7.88E+Ol 

2.71E+02 

7.08E+Ol 

3. 81E-Ol 

STABLE 

1. 92E+03 

7.27E-03 

6.88E-02 
ELEMENT DATA SHEET 

ELEMENT: NICKEL 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2.00E-02 

6.80E-Ol 

3.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I!DAYS 

3. 47E+00 

2. 77E+OO 

5. 77E-04 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E*02 INGESTION 

5.00E-02 CLASS D 5.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF NICKEL: 

O.OOE+OO CLASS Y 

MASS NUMBER 

56 

51 

58 

59 

63 

65 

66 

HALFLIFE, DAYS 

6.10E+00 

1.50E+OO 

STABLE 

2. 14E+07 

3.50E+04 

1.05E-Ol 

2. 28E+00 

B-734 
ELEMENT DATA SHEET 

ELEMENT: COPPER 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E-Ol INGESTION 

---~~----------~~-~------~~---------

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

1.73E-02 

5.00E";01 CLASS D 5.00E-Ol CLASS W 5.00E-Ol CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF COPPER: MASS NUMBER 

60 

61 

63 

64 

67 

8-735 

HALFLIFE, DAYS 

1.61E-02 

1. 42E-01 

STABLE 

5. 29E-Ol 

2. 58E+00 
ELEMENT DATA SHEET 

ELEMENT: ZINC 

...... -----

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00£-02 

COEFFICIENT 

7.60E-Ol 

2.40E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1. 73E-03 

3. 47E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E-Ol INGESTION 

O.OOE+OO CLASS D O.OOE+OO CLASS W 5.00E-01 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 2.50E-01 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 7.50E-Ol 

THE COMMON ISOTOPES OF ZINC: 

-------------------------~ 

MASS NUMBER 

62 

63 

65 

66 

69 

69m 

71m 

72 

B-736 

HALFLIFE, DAYS 

3. 86E-01 

2. 65E-02 

2. 44E+02 

STABLE 

3. 96E-02 

5. 73E-Ol 

1. 63E-Ol 

1. 94E+00 
ELEMENT DATA SHEET 

ELEMENT: GALLIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.IOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.00E-Ol 

7.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

6. 93E-Ol 

1. 39E-02 

FRACTION FROM GI TRACT TO BLOOD (f 1): 1.00£-03 INGESTION 

-----...... ----------....-,-_-.-...----------

1.00E-03 CLASS D 1.00E-03 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF GALLIUM: MASS NUMBER HALFLIFE, DAYS 

65 

66 

67 

68 

69 

70 

12 

73 

B-737 

1.06E-02 

3. 92E-Ol 

3. 26E+00 

4. 72E-02 

STABLE 

1. 47E-02 

5. 88E-Ol 

2.05E-Ol 
ELEMENT DATA SHEET 

ELEMENT: GERMANIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

1.OOE+OO CLASS D 1.OOE+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF GERMANIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-Ol 

5.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT,· 

l/DAYS 

2. 77E+OO 

6. 93E-Ol 

1.OOE+OO INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

66 

67 

68 

69 

71 

73 

75 

77 

78 

HALFLIFE, DAYS 

9. 46E-02 

1.30E-02 

2. 88E+02 

1. 63E+OO 

1.18E+Ol 

STABLE 

5.7SE-02 

4.71E-Ol 

6.04E-02 

B-738 
ELEMENT DATA SHEET 

ELEMENT: ARSENIC 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

O.OOE+OO CLASS D 5.00E-Ol CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ARSENIC: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.50E-Ol 

2.60E-Ol 

3.90E-Ol 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

2. 77E+OO 

6. 93E-Ol 

6. 93E-02 

5.00E-Ol INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

69 

70 

71 

72 

73 

74 

75 

76 

77 

HALFLIFE; DAYS 

1.06E-02 

3. 65E-02 

2.70E+00 

1.08E+00 

8.03E+Ol 

1. 78E+Ol 

STABLE 

1.10E+00 

1.62E+00 

B-739 
ELEMENT DATA SHEET 

ELEMENT: SELENIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lDE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-01 

4.00E-0l 

5.00E-0l 

FRACTION FROM GI TRACT TO BLOOD (£1): 8.00E-01 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-01 

RATE CONSTANT, 

l/DAYS 

2.31E-01 

2.31E-02 

4. 62E-03 

8.00E-01 CLASS D 8.00E-01 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF SELENIUM: MASS NUMBER 

70 

73 

73m 

75 

78 

79 

. 81 

81m 

83 

B-740 

HALFLIFE, DAYS 

2.85E-02 

2. 98E-01 

2.71E-02 

1.20E+02 

STABLE 

2.37E+07 

1. 29E-02 

3. 98E-02 

1. 56E-02 
ELEMENT DATA SHEET 

ELEMENT: BROMINE 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.OOE+OO 

PUUiONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT t 

l/DAYS 

6. 93E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 1.00E+OO INGESTION 

1. OOE+OO CLASS D 1.OOE+OO CLASS W' O.OOE+OO CLASS Y . 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF BROMINE: MASS NUMBER HALFLIFE t DAYS 

74 

74m 

75 

76 

77 

79 

80 

80m 

82 

83 

84 

B-741 

1. 76E-02 

2. 88E-02 

6.81E-02 

6. 75E-Ol 

2. 33E+OO 

STABLE 

1.21E-02 

1.84E-Ol 

1. 47E+OO 

9. 96E-02 

2. 21E-02 
ELEMENT DATA SHEET 

ELm~ENT: RUBIDIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-0l 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1.58E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 1.00E+OO INGESTION 

1.00E+OO CLASS D O.OOE+OO CLASS W O.OOE+OO CLASSY 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 7.50E-Ol 

--------------------------------------------------~----

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 2.50E-01 

THE COMMON ISOTOPES OF RUBIDIUM: MASS NUMBER 

79 

81 

81m 

82m 

83 

84 

85 

86 

87 

88 

89 

B-742 

HALFLIFE, DAYS 

1.59E-02 

1.91E-0l 

2. 22E-02 

2. 58E-01 

8. 62E+01 

3. 28E+01 

STABLE 

1. 87E+01 

1. 72E+13 

1. 24E-02 

1.06E-02 
ELEMENT DATA SHEET 

ELEMENT: STRONTIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION:· 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.29E-Ol 

6.99E-02 

5. 89E-Ol 

2. 71E-02 

6. 65E-02 

5.80E-02 

6.03E-02 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

2. 56E+Ol 

5. 57E-Ol 

1.59E-Ol 

1. 23E-02 

3.30E-03 

3. 72E-04 

8. 43E-05 

FRACTION FROM GI TRACT TO BLOOD (f 1): 3.00E-Ol INGESTION 

3.00E-Ol CLASS D O.OOE+OO CLASS W 1.00E-02 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 8.50E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 1.50E-Ol 

THE COMMON ISOTOPES OF STRONTIUM: MASS NUMBER 

-----------

83 

85 

85m 

88 

89 

90 

B-743 

HALFLIFE, DAYS 

1. 35E+OO 

6. 48E+Ol 

4. 83E-02 

STABLE 

5.05E+Ol 

1.06E+04 
ELEMENT DATA SHEET 

ELEMENT: YTTRIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3. 1 OE-O 1 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.50E-01 

2.50E-Ol 

1.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1.00E-10 

2. 77E+OO 

O.OOE+OO CLASS D 1.00E-04 CLASS W 1.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF YTTRIUM: MASS NUMBER 

86 

86m 

87 . 88 

89 

90 

90m 

91 

92 

93 

94 

B-744 

HALFLIFE, DAYS 

6. 14E-Ol 

3. 33E-02 

3. 35E+00 

1.07E+02 

STABLE 

2. 67E+00 

1. 33E-Ol 

5. 85E+Ol 

1.47E-Ol 

4. 21E-Ol 

1. 33E-02 
ELEMENT DATA SHEET 

ELEMENT: ZIRCONIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-0l 

5.00E-Ol 

FRACTION FROM GI TRACT TO BLOOD (£1): 2.00E-03 INGESTION 

~--------------------------------~ 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

IjDAYS 

8. 66E-05 

9.90E-02 

2.00E-03 CLASS D 2.OOE-03 CLASS W 2.00E-03 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ZIRCONIUM: MASS NUMBER 

86 

88 

89 

91 

93 

95 

97 

B-745 

HALFLIFE, DAYS 

6. 88E-Ol 

8. 34E+Ol 

3. 27E+OO 

STABLE 

5. 59E+08 

6.40E+Ol 

7.04E-Ol 
ELEMENT DATA SHEET 

ELEMENT: NIOBIUM 

PARTICLE SIZE: 1.OB+OO MICRONS 

LUNG DEPOSITION: ~SAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

---~-----------------~--------------

O.OOE+OO CLASS D l.OOE-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

----------------------------------

THE COMMON ISOTOPES OF NIOBIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5. DOE-Ol 

5.00E-0l 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

l.l6E-Ol 

3. 47E-03 

l.00E-D2 INGESTION 

l.00E-02 CLASS Y 

MASS NUMBER 

88 

89 

89 

90 

93 

93m 

94 

95 

95m 

96 

97 

HALFLIFE. DAYS 

9. 93E-03 

4. 58E-02 

8. 47E-02 

6.08E-Ol 

STABLE 

4. 96E+03 

7.41E+06 

3. 52E+Ol 

3.61E+OO 

9. HE-Ol 

5.01E-02 

B-746 
ELEMENT DATA SHEET 

ELEMENT: MOLYBDENUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-Ol 

9.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

6. 93E-Ol 

1. 39E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 8.00E-Ol INGESTION 

8.00E-Ol CLASS D O.OOE+OO CLASS W 5.00E-02 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF MOLYBDENUM: MASS NUMBER HALFLIFE, DAYS 

90 

93 

93m 

96 

99 

101 

B-747 

2. 36E-Ol 

1. 28E+06 

2. 85E-Ol 

STABLE 

2. 75E+00 

1.02E-02 
ELEMENT DATA SHEET 

ELEMENT: TECHNETIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.00E-02 

7.20E-Ol 

1. 92E-01 

4.80E-02 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1.39E+00 

4. 33E-01 

1.87E-01 

3.1SE-02 

FRACTION FROM GI TRACT TO aLOOD (f1): 8.00E-01 INGESTION 

8.00E-01 CLASS D 8.00E-01 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TECHNETIUM: MASS NUMBER HALFLIFE, DAYS 

93 

93m 

94 

94m 

96 

97 

98 

99 

101 

104 

B-748 

1.lSE-01 

3.02E-02 

2.03E-01 

3. 61E-02 

4. 28E+00 

9. 49E+08 

1. S3E+09 

7.77E+07 

9. 86E-03 

1. 26E-02 
ELEMENT DATA SHEET 

ELEMENT: RUTHENIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.SOE-0l 

3.00E-Ol 

2.00E-Ol 

1.50E-Ol 

PULMONARY 

PARENCHYMA. 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

8. 66E-02 

1. 98E-02 

6. 93E-04 

2. 31E+OO 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E-02 INGESTION 

5.00E-02 CLASS D 5.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF RUTHENIUM: 

5.00E-02 CLASS Y 

MASS NUMBER 

94 

97 

101 

103 

105 

106 

HALFLIFE, DAYS 

3.60E-02 

2.90E+OO 

STABLE 

3. 93E+Ol 

1. 85E-0l 

3. 68E+02 

B-749 
ELEMENT DATA SHEET 

ELEl-lENT: RHODIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.50E-01 

3.00E-Ol 

2.00E-Ol 

1.50E-01 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

8. 66E-02 

1.98E-02 

6. 93E-04 

2.31E+00 

FRACTION FROM GI TRACT TO BLOOD (£1): 5.00E-02 INGESTION 

5.00E-02 CLASS D 5.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF RHODIUM: 

------~----------~------------

5.00E-02 CLASS Y 

MASS NUMBER 

99 

99m 

100 

101 

101m 

102 

103 

105 

107 

HALFLIFE, DAYS 

1.60E+Ol 

1. 96E-0l 

8. 67E-Ol 

1. 17E+03 

4. 34E+00 

1.06E+03 

STABLE 

1. 47E+00 

1.51E-02 

B-750 
ELEMENT DATA SHEET 

ELEMENT: PALLADIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.00E-01 

7.00E-01 

FRACTION FROM GI TRACT TO BLOOD (£1): 5.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

2. 77E+00 

4. 62E-02 

5.00E-03 CLASS D 5.00E-03 CLASS W 5.00E-03 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF PALLADIUM: MASS NUMBER 

100 

101 

103 

106 

107 

109 

B-751 

HALFLIFE, DAYS 

3. 63E+00 

3. 45E-01 

1.70E+01 

STABLE 

2. 37E+09 

5.60E-01 
ELEMENT DATA SHEET 

ELEMENT:. SILVER 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-01 

9.008-01 

PULMONARY 

PARENCHYMA. 

2.49E-01 

RATE CONSTANT, 

l/DAYS 

1.98E-01 

1. 39E-02 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E-02 INGESTION 

5.00E-02 CLASS D 5.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF SILVER: 

5.00E-02 CLASS Y 

MASS NUMBER 

102 

103 

104 

104m 

105 

106 

106m 

108 

III 

112 

115 

HALFLIFE, DAYS 

8. 96E-03 

4. 56E-02 

4. 81E-02 

2. 33E-02 

4.lOE+01 

1. 66E-02 

8. 41E+00 

STABLE 

7. 45E+00 

1.30E-01 

1.39E-02 

B-752 
ELEMENT DATA SHEET 

ELEMENT: CADMIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.IOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

FRACTION FROM GI TRACT TO BLOOD (f1): 5.00E-02 INGESTION 

- ------------------------------------

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

7.60E-05 

5.00E-02 CLASS D 5.00E-02 CLASS W 5.00E-02 CLASS Y 

EXCRETION PATHWAYS·ARE NOT DEFINED: 

THE COMMON ISOTOPES OF CADMIUM: MASS NUMBER 

104 

107 

109 

112 

113 

113m 

115 

115m 

117 

B-753 

HALFLIFE, DAYS 

-------------

4.00E-02 

2.70E-Ol 

4. 64E+02 

STABLE 

3.40E+18 

4. 96E+03 

2. 23E+00 

4. 46E+Ol 

1.04E-Ol 
ELEMENT DATA SHEET 

ELEMENT: INDIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT ~ 

l/DAYS 

1.00E-1O 

FRACTION FROM GI TRACT TO BLOOD (£1): 2.00E-02 INGESTION 

----------------------------------~ 

2.00E-02 CLASS D 2.00E-02 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF INDIUM: t4ASS NUMBER HALFLIFE t DAYS 

109 

110 

110 

III 

112 

113m 

114 

114m 

115 

117 

B-754 

_ ......... _--------

1. 75E-01 

4.80E-02 

2.04E-Ol 

2. 83E+00 

1.00E-02 

6. 91E-02 

STABLE 

4. 95E+Ol 

1.86E+18 

3.04E-02 
ELEMENT DATA SHEET 

"ELEMENT: TIN 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-01 

1.00E-0i 

1.OOE-0i 

3.00E-0l 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT. 

l/DAYS 

2. 77E+OO 

1.73E-01 

2. 77E-02 

1.73E-03 

FRACTION FROM GI TRACT TO BLOOD (f1): 2.00E-02 INGESTION 

2.00E-02 CLASS D 2.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TIN: 

O.OOE+OO CLASS Y 

MASS NUMBER 

110 

III 

113 

119 

121 

125 

126 

127 

128 

HALFLIFE, DAYS 

1. 67E-Ol 

2. 45E-02 

1. 15E+02 

STABLE 

1.13E+00 

9. 64E+00 

3. 65E+07 

8. 75E-02 

4.10E-02 

8-755 
ELEMENT DATA SHEET 

ELEMENT: ANTIMONY 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol . 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

1.00E-Ol CLASS D 1.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ANTIMONY: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2.00E-Ol 

7.60E-Ol 

4.00E-02 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

2.77E+00 

1. 39E-Ol 

6. 93E-03 

1.00E-Ol INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

115 

116 

116m 

117 

118m 

119 

120 

120 

121 

122 

124 

HALFLIFE, DAYS 

2.21E-02 

1.IOE-02 

4. 19E-02 

1. 17E-Ol 

2.08E-Ol 

1. 59E+00 

1.10E-02 

5. 76E+00 

STABLE 

2.70E+00 

6.02E+Ol 

B-756 
ELEMENT DATA SHEET 

ELEMENT: TELLURIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-Ol 

2.50E-Ol 

2.50E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

8. 66E-Ol 

1. 39E-04 

3. 47E-02 

FRACTION FROM GI TRACT TO BLOOD (fl ): 2.00E-Ol INGESTION 

2.00E-Ol CLASS D 2.00E-Ol CLASS W O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 7.50E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 2.50E-Ol 

THE COMMON ISOTOPES OF TELLURIUM: MASS NUMBER 

116 

121 

121m 

123 

123m 

127 

128 

129 

131 

132 

133 

B-757 

HALFLIFE, DAYS 

I.04E-OI 

1.70E+OI 

I. 54E+02 

3. 65E+15 

1.20E+02 

3.90E-OI 

STABLE 

4. 83E-02 

1.74E-02 

3. 26E+OO 

8. 65E-03 
ELEMENT DATA SHEET 

ELEMENT: IODINE 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

THYROID RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

1.OOE+00 CLASS D O.OOE+OO CLASS W 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.00E-Ol 

- 3.47E-02 

3.35E-Ol 

COEFFICIENT 

- 3.0IE-01 

1.50E-02 

2. 86E-Ol 

1.00E+OO INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

2.77E+00 

6.02E-02 

6.05E-03 

RATE CONSTANT, 

l/DAYS 

2. 77E+OO 

6.02E-02 

6.05E-03 

O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 9.7E-OI 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 3.0E-02 

THE COMt-WN ISOTOPES OF IODINE: MASS NUMBER 

120 

120m 

121 

123 

1~4 

125 

126 

127 

128 

129 

131 

132 

133 

134 

135 

B-758 

HALFLIFE, DAYS 

5. 63E-02 

3. 68E-02 

8. 83E-02 

5.50E-01 

4. 18E+00 

6.01E+Ol 

1.30E+Ol 

STABLE 

I. 74E-02 

5. 73E+09 

8.04E+00 

9. 58E-02 

8. 67E-01' 

3. 65E-02 

2. 74E-Ol 
ELEMENT DATA SHEET 

ELEMENT: CESIUM 

PARTICLE SIZE: 1.OE+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-01 

9.00E-01 

1.00E+OO INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-01 

RATE CONSTANT, 

l/DAYS 

3.47E-01 

6.30E-OJ 

1.00E+OO CLASS D O.OOE+OO CLASS W O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 8.00E-OI 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 2.00E-01 

THE COMMON ISOTOPES OF CESIUM: MASS NUMBER 

125 

127 

129 

130 

131 

132 

133 

134 

134m 

135 

135m 

B-759 

HALFLIFE, DAYS 

3.13E-02 

2.60E-01 

1. 34E+OO 

2.08E-02 

9. 69E+OO 

6.48E+OO 

STABLE 

7.53E+02 

I.21E-01 

8.40E+08 

3. 68E-02 
ELEMENT DATA SHEET 

ELEMENT: BARIUM 

PARTICLE SIZE: 1.OE+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM G1 TRACT TO BLOOD (f l ): 

1.00E-Ol CLASS D O.OOE+OO CLASS W 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.63E-Ol 

2. 62E-Ol 

1.15E-0l 

2.lOE-02 

1.02E-02 

1.35E-02 

1.60E-02 

1.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT J 

I/DAYS 

5. 46E+Ol 

6.21E-Ol 

2. 38E-Ol 

7.92E-03 

1. 82E-03 

5.05E-04 

1. 29E-04 

O. OOE+OO Cl..ASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 1.00E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 9.00E-Ol 

THE COMMON ISOTOPES OF BARIUM: MASS NUMBER 

128 

131 

133 

133m 

137 

140 

B-760 

HALFLIFE, DAYS 

2. 43E+OO 

1. 18E+Ol 

3.92E+03 

1. 62E+00 

STABLE 

1.27E+Ol 
ELEMENT DATA SHEET 

ELEMENT: LANTHANUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.IOE-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

1.00E-03 CLASS D 1.00E-03 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF LANTHANUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

I/DAYS 

1.98E-04 

1.00E-03 INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

131 

132 

135 

137 

138 

139 

140 

141 

142 

HALFLIFE, DAYS 

4.IOE-02 

2.00E-Ol 

8.13E-Ol 

2. 19E+07 

4. 93E+13 

STABLE 

1.68E+00 

1. 64E-01 

6.42E-02 

B-761 
ELEMENT DATA SHEET 

ELEMENT: CERIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f1): 

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF CERIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, . 

I/DAYS 

1.98E-04 

3.00E-04 INGESTION 

3.00E-04 CLASS Y 

MASS NUMBER 

134 

135 

137 

137m 

139 

140 

141 

143 

144 

HALFLIFE, DAYS 

3.00E+00 

7.33E-Ol 

3.75E-01 

1.43E+00 

1.38E+02 

STABLE 

3. 25E+Ol 

1. 38E+00 

2.84E+02 

B-762 
ELEMENT DATA SHEET 

ELEMENT: PRASEODYMIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

8.50E-O! 

5.00E-02 

1.00E-O! 

FRACTION FROM GI TRACT TO BLOOD (f 1): 3.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

I/DAYS 

1.98E-04 

6. 93E-02 

2.77E+OO 

O.OOE+OO CLASSD 3.00E-04 CLASS W 3.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF PRASEODYMIUM: 

B-763 

MASS NUMBER 

136 

137 

138m 

139 

141 

142 

142m 

143 

144 

145 

147 

HALFLIFE, DAYS 

9.lOE-03 

5. 32E-02 

8. 75E-02 

1. 88E-Ol 

STABLE 

7.98E-Ol 

1.01E-02 

1. 36E+Ol 

1.20E-02 

2. 49E-Ol 

9. 44E-03 
ELEMENT DATA SHEET 

ELEMENT: NEODYMIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

9.00E-Ol 

1.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT J 

I/DAYS 

1. 98E-04 

2. 77E+OO 

FRACTION FROM GI TRACT TO BLOOD (£1): 3.00E-04 INGESTION 

O.OOE+OO CLASS D 3.00E-04 CLASS W 3.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE CO~lON ISOTOPES OF NEODYMIUM: MASS NUMBER HALFLIFE, DAYS 

136 

138 

139 

141 

144 

147 

149 

151 

B-764 

3. 52E-02 

2.lOE-OI 

2.06E-02 

1.04E-Ol 

STABLE 

l.lOE+Ol 

7. 21E-02 

8. 64E-03 
ELEMENT DATA SHEET 

ELEMENT: PROMETHIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E-Ol 

9.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

2. 77E+00 

1. 98E-04 

FRACTION FROM GI TRACT TO BLOOD (£1): 3.00E-04 INGESTION 

-----~------------------------------

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

----------------------------------

THE COMl'lON ISOTOPES OF PROMETHIUM: 

3.00E-04 CLASS Y 

MASS NUMBER 

141 

143 

144 

145 

146 

147 

148 

148m 

149 

HALFLIFE, DAYS 

1. 45E-02 

2. 65E+02 

3. 63E+02 

6. 46E+03 

2.02E+03 

9. 58E+02 

5. 37E+00 

4. 13E+Ol 

2.21E+00 

B-765 
ELEMENT DATA SHEET 

ELEMENT: SAMARIUM 

PARTICLE SIZE: 1.0E+00 !HCRONS 

LUNG DEPOSITION: NASAL 

------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

9.00E-Ol 

1.00E-01 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

1!DAYS 

1.98E-04 

2.77E+00 

FRACTION FROM GI TRACT TO BLOOD (£1): 3.00E-04 INGESTION 

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE CO~MON ISOTOPES OF SAMARIUM: 

O.OOE+OO CLASS Y 

MASS NmmER 

141 

141m 

142 

145 

146 

147 

150 

151 

153 

155 

HALFLIFE, DAYS 

7.08E-03 

i.57E-02 

5.03E-02 

3.40E+02. 

3. 76E+1O 

3. 87E+13 

STABLE 

3. 29E+04 

1.95E+00 

1.54E-02 

-B-766 
ELEMENT DATA SHEET 

ELEMENT: EUROPIUM 

PARTICLE SIZE: I.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3. IOE-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (fI ): 

O.OOE+OO CLASS D I.00E-03 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF EUROPIUM: 

B-767 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

8.00E-OI 

6.00E-02 

I.40E-OI 

I.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-OI 

RATE CONSTANT, 

I/DAYS 

I.98E-04 

6. 93E-02 

2. 77E+OO 

O.OOE+OO CLASS Y 

MASS NUMBER 

145 

146 

147 

148 

149 

150 

150 

151 

152 

152m 

HALFLlFE, DAYS 

5. 94E+00 

4.6IE+OO 

2.40E+OI 

5.45E+OI 

9.3IE+OI 

5. 26E-OI 

1. 25E+04 

STABLE 

4. 87E+03 

3. 88E-OI 
ELEMENT DATA SHEET 

ELEMENT: GADOLINIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

3.00E-04 CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF GADOLINIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.50E-01 

3.00E-02 

2.20E-01 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1. 98E-04 

6. 93E-02 

2. 77E+OO 

3.00E-04 INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

145 

146 

147 

148 

14.9 

151 

152 

153 

157 

HALFLIFE, DAYS 

1. 59E-02 

4. 83E+01 

1. 59E+OO 

3. 39E+04 

9.40E+OO 

1.20E+02 

J-.94E+16 

2. 42E+02 

STABLE 

'8-768 
ELEMENT DATA SHEET 

ELEMENT: TERBIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-0l 

SYSTEMIC RETENTION: 

FRACTION ,ROM GI TRACT TO BLOOD (£1): 

~----------------------------------

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TERBIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.50E-Ol 

5.00E-02 

2.00E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

1. 98E-04 

6. 93E-02 

2. 77E+00 

3.00E-04 INGESTION 

O.OOE+OO CLASS Y 

MASS NilltBER -----......... _--

147 

149 

150 

151 

153 

154 

155 

156 

156m 

156m 

159 

HALFLIFE, DAYS 

6. 88E-02 

1.73E-Ol 

1. 36E-Ol 

7. 33E-Ol 

2. 34E+00 

8. 92E-Ol 

5. 32E+00 

5. 34E+00 

1.02E+00 

2.08E-Ol 

STABLE 

B"':769 
ELEMENT DATA SHEET 

ELEMENT: DYSPROSIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-0l 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.00E-Ol 

2.00E-02 

2.80E-Ol 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

1. 98E-04 

6. 93E-02 

2.77E+OO 

FRACTION FROM GI TRACT TO BLOOD (f 1): 3.OOE-04 INGESTION 

O.OOE+OO CLASS D 3.OOE-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF DYSPROSIUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

155 

157 

159 

162 

165 

166 

HALFLIFE, DAYS 

4. 17E-Ol 

3. 38E-Ol 

1. 44E+02 

STABLE 

9. 73E-02 

3.40E+OO 

B-770 
ELEMENT DATA SHEET 

ELEMENT: HOLMIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

"------------------

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

8. SOE-Ol 

I.S0E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

1. 98E-04 

2. 77E+OO 

FRACTION FROM GI TRACT TO BLOOD (£1): 3.00E-04 INGESTION 

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF HOLMIUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

155 

157 

159 

161 

162 

162m 

164 

164m 

165 

166 

HALFLIFE, DAYS 

3. 33E-02 

8. 75E-03 

2. 29E-02 

1.04E-Ol 

1.04E-02 

4.72E-02 

2.01E-02 

2.60E-02 

STABLE 

1. 12E+OO 

B-771 
ELEMENT DATA SHEET 

ELEMENT: ERBIUM 

PARTICLE SIZE: 1. OE+OO ~lICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.50E-Ol 

2.50E-Ol 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

I! DAYS 

1. 98E-04 

2.77E+OO 

FRACTION FROM GI TRACT TO BLOOD (£1): 3.00E-04 INGESTION 

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ERBIUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

161 

165 

167 

169 

171 

172 

HALFLIFE, DAYS 

1. 35E-Ol 

4. 32E-Ol 

STABLE 

9.30E+OO 

3.13E-Ol 

2.05E+OO 

B-772 
ELEMENT DATA SHEET 

ELEMENT: THULIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-OI 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.90E-Ol 

2.10E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

1.98E-04 

2. 77E+OO 

FRACTION FROM GI TRACT TO BLOOD (f1): 3.00E-04 INGESTION 

-----------------------~-----------

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

----------------------------------

THE COMMON ISOTOPES OF THULIUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

162 

166 

167 

169 

170 

171 

172 

173 

175 

HALFLIFE, DAYS 

1.51E-02 

3.21E-0l 

9. 24E+00 

STABLE 

1. 29E+02 

7.01E+02 

2. 65E+00 

3.43E-Ol 

1.06E-02 

B-773 
ELEMENT DATA SHEET 

ELEMENT: YTTERBIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3. 1 OE-O 1 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

------------------------------------

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5. 35E-Ol 

2.00E-02 

4. 45E-Ol 

3.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTAN'l', 

l/DAYS 

1.98E-04 

6. 93E-02 

2. 27E+OO 

O.OOE+OO CLASS D 3.00E-04 CLASS W 3.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF YTTERBIUM: MASS NUMBER 

162 

166 

167 

169 

173 

175 

177 

178 

B-774 

HALFLIFE, DAYS 

1.3IE-02 

2. 36E+OO 

1.22E-02 

3.20E+Ol 

STABLE 

4. 19E+OO 

7. 92E-02 

5. 14E-02 
ELEMENT DATA SHEET 

ELEMENT: LUTETIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

O.OOE+OO CLASS D 3.00E-04 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF LUTETI.UM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

6.20E-Ol 

5.00E-03 

3. 75E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I!DAYS 

1.98E-04 

6. 93E-02 

2. 27E+00 

3.00E-04 INGESTION 

3.00E-04 CLASS Y 

MASS NUMBER 

169 

170 

171 

172 

173 

174 

174m 

175 

176 

176m 

HALFLIFE, DAYS 

1. 42E+00 

2.00E+OO 

8. 22E+00 

6.70E+00 

5.00E+02 

1.21E+03 

1. 42E+02 

STABLE 

1.31E+13 

1.53E-OI 

B-775 
ELEMENT DATA SHEET 

ELEMENT: HAFNIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-0l 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5.00E-Ol 

5.00E-Ol 

FRACTION FROM GI TRACT TO BLOOD (£1): 2.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

8. 66E-05 

9.90E-02 

2.00E-03 CLASS D 2.00E-03 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF HAFNIUM: MASS NUMBER 

170 

172 

173 

175 

177m 

178m 

179 

181 

182 

183 

B-776 

HALFLIFE, DAYS 

6.67E-01 

6. 83E+02 

1.00E+00 

7.00E+01 

3. 57E-02 

1. 13E+04 

STABLE 

4. 24E+01 

3. 29E+09 

4. 44E-02 
, -.'./ " 

ELEMENT DATA SHEET 

ELEMENT: TANTALUM 

PARTICLE SIZE: I.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (fI ): 

O.OOE+OO CLASS D 1.00E-03 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TANTALUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

3.50E-0l 

6.50E-0l 

PULMONARY 

PARENCHYMA 

2. 49E-OI 

RATE CONSTANT, 

I/DAYS 

1. 73E-OI 

o.93E-03 

I.OOE-03 INGESTION 

1.00E-03 CLASS Y 

MASS NUMBER 

172 

173 

174 

175 

176 

177 

178 

180m 

181 

182m 

HALFLIFE, DAYS 

2. 56E-02 

1. 52E-OI 

5.00E-02 

4. 38E-OI 

3. 37E-Ol 

2. 36E+OO 

9.20E-02 

3. 38E-OI 

STABLE 

1.10E-02 

1-777 
ELEMENT DATA SHEET 

ELEMENT: TUNGSTEN 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

-----~--------------------~---------

3.00E-Ol CLASS D O.OOE+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF TUNGSTEN: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

9.50E-0l 

2.25E-02 

1.00E-02 

1. 75E-02 

1.00E-02 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

2. 77E+OO 

1. 39E-Ol 

6. 93E-03 

6. 93E-04 

O.OOE+OO CLASS Y 

MASS NUMBER 

176 

177 

178 

179 

181 

184 

185 

187 

188 

HALFLIFE, DAYS 

9. 59E-02 

9. 38E-02 

2. 17E+Ol 

2.60E-02 

1.21E+02 

STABLE 

7.51E+01 

9. 96E-01 

6. 94E+01 

B-778 
ELEMENT DATA SHEET 

ELEMENT: RHENIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.00E-02 

7.20E-01 

1. 92E-01 

4.80E-02 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l!DAYS 

1. 39E+OO 

4. 33E-01 

1. 87E-01 

3. 15E-02 

FRACTION FROM GI TRACT TO BLOOD (£1): 8.00E-01 INGESTION 

8.00E-01 CLASS D 8.00E-01 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF RHENIUM: 

O.OOE+OO CLASS Y 

MASS NUMBER 

177 

178 

181 

182 

182 

184 

184m 

186 

186m 

187 

HALFLlFE, DAYS 

9. 72E-03 

9. 17E-03 

8. 33E-01 

2. 67E+OO 

5. 53E-01 

3.80E+Ol 

1. 65E+02 

3. 78E+OO 

7.30E+07 

1. 83E+13 

B-779 
ELEMENT DATA SHEET 

ELEMENT: OSMIUM 

PARTICLE SIZE: 1.OE+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.60E-01 

6.40E-01 

2.00E-Ol 

1.00E-02 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

8. 66E-02 

3. 47E-03 

2.77E+00 

1.00E-02 CLASS D 1.00E-02 CLASS W 1.00E-02 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF OSMIUM: MASS NUMBER 

180 

181 

182 

185 

189m 

190 

191 

191m 

193 

194 

B-780 

HALFLIFE, DAYS 

1. 53E-02 

7.29E-02 

9.17E-0l 

9.40E+Ol 

2.50E-Ol 

STABLE 

1.54E+Ol 

5.43E-Ol 

1.25E+OO 

2.19E+03 
ELEMENT DATA SHEET 

ELEMENT: IRIDIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

1.00E-02 CLASS D 1.00E-02 CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF IRIDIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1 .. 60E-Ol 

6.40E-Ol 

2.00E-0l 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

8. 66E-02 

3. 47E-03 

2. 17E+OO 

1.00E-02 INGESTION 

1.00E-02 CLASS Y 

MASS NUMBER 

182 

184 

185 

186 

187 

188 

189 

190 

190m 

192m 

193 

HALFLIFE, DAYS 

1.04E-02 

1. 26E-Ol 

5. 83E-ol 

6. 58E-Ol 

4. 38E-Ol 

1.73E+OO 

1. 33E+Ol 

1. 21E+01 

5.00E-02 

8.80E+04 

STABLE 

B-781 
. <,:: 

ELEMENT DATA SHEET 

ELEMENT: PLATINUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

l.00E-02 CLASS 0 O.OOE+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE CO~n-lON ISOTOPES OF PLATINUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2.00E-Ol 

7.60E-Ol 

4.00E-02 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

2.77E+00 

8. 66E-02 

3.47E-03 

l.00E-02 INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

186 

188 

189 

191 

193 

193m 

195 

195m 

197 

199 

200 

HALFLIFE, DAYS 

8. 33E-02 

1.02E+01 

4. 53E-Ol 

2.80E+OO 

l.83E+04 

4. 33E+OO 

STABLE 

4.02E+00 

7.63E-01 

2. 14E-02 

5.21E-Ol 

B-782 
ELEMENT DATA SHEET 

. ELEMENT: GOLD 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

1.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT t 

I/DAYS 

2.31E-Ol 

1.00E-Ol CLASS D 1.00E-Ol CLASS W 1.00E-Ol CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF GOLD: MASS NUMBER 

193 

194 

195 

197 

198 

198m 

199 

200 

200m 

201 

B-783 

HALFLIFE, DAYS 

7. 35E-Ol 

1.65E+00 

1. 83E+02 

STABLE 

2.70E+00 

2.30E+00 

3. 14E+OO 

3. 36E-02 

7. 79E-Ol 

1. 83E-02 

I 
ELEMENT DATA SHEET 

ELEMENT: MERCURY (ORG.) 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.l0E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

9. SOE-Ol 

5.00E-02 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT. 

l!DAYS 

8. 66E-03 

6. 93E-OS 

FRACTION FROM GI TRACT TO BLOOD (f 1): 4.00E-Ol INGESTION 

1.00E+00 CLASS D O.OOE+OO CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF MERCURY(ORG.) MASS NUMBER HALFLIFE, DAYS 

193 

193m 

194 

195 

195m 

197 

200 

203 

B-784 

1. 46E-Ol 

4.63E-Ol 

9. 49E+04 

4. 13E-Ol 

1. 73E+00 

2. 67E+00 

STABLE 

4. 66E+Ol 
ELEMENT DATA SHEET 

ELEMENT: THALLIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

1.00E+00 CLASS D O.OOE+OO CLASS W 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMl'ION ISOTOPES OF THALLIUM: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

6. 93E-02 

1.00E+00 INGESTION 

O.OOE+OO CLASS Y 

MASS NUMBER 

194 

194m 

195 

197 

198 

198m 

199 

200 

201 

202 

205 

HALFLIFE, DAYS 

2.30E-02 

2. 28E-02 

4.a3E-02 

1. 18E-01 

2.21E-01 

7. 79E-02 

3.10E-01 

1.09E+00 

3.04E+00 

1. 22E+01 

STABLE 

B-785 
ELEMENT DATA SHEET 

ELEMENT: LEAD 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

6.90E-01 

1.91E-Ol 

1. 19E-Ol 

FRACTION FROM GI TRACT TO BLOOD (£1): 2.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

5. 78E-02 

3. 85E-03 

6. 93E-05 

2.00E-Ol CLASS D O.OOE+OO CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF LEAD: MASS NUMBER 

195m 

198 

199 

200 

201 

202 

202m 

203 

205 

207 

209 

B-786 

HALFLIFE f DAYS 

1.IOE-02 

1.00E-Ol 

6. 25E-02 

8. 96E-Ol 

3. 92E-Ol 

1.IOE+08 

1.51E-01 

2. 17E+00 

5. 22E+09 

STABLE 

1.36E-Ol 
ELEMENT DATA SHEET 

ELEMENT: BISMUTH 

PARTICLE SIZE: 1.OE+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.20E-01 

2.80E-0l 

3.00E-Ol 

FRACTION FROM GI TRACT TO BLOOD (£1): 5.00E-02 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

l/DAYS 

1.16E+00 

1. 39E-01 

2. 77E+OO 

5.00E-02 CLASS D 5.00E-02 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF BISMUTH: MASS NUHBER 

200 

201 

202 

203 

205 

206 

207 

209 

210 

210m 

B-787 

HALFLIFE, DAYS 

2. 53E-02 

7.50E-02 

6. 96E-02 

4.90E-01 

1. 53E+01 

6. 24E+00 

1. 39E+04 

STABLE 

5.01E+00 

1.10E+09 
ELEMENT DATA SHEET 

ELEMENT: POLONIUM 

PARTICLE SIZE: 1.OE+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

I.OOE-OI CLASS D 1.00E-01 CLASS W 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

1.00E-01 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-OI 

RATE CONSTANT, 

l/DAYS 

1. 39E-02 

O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 1.00E-01 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 9.00E-OI 

THE COMMON ISOTOPES OF BERYLLIUM: MASS NUMBER 

203 

205 

207 

210 

B-788 

HALFLIFE, DAYS 

2. 55E-02 

7.50E-02 

2.43E-OI 

1. 38E+02 
ELEMENT DATA SHEET 

ELEMENT: ASTATINE 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- P~SSAGES 

3.1OE-01 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+00 

1.00E+00 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

I/DAYS 

6. 93E-02 

1.00E+00 CLASS D 1.00E+00 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ASTATINE: MASS NUMBER 

207 

209 

211 

B-789 

HALFLIFE, DAYS 

7.50E-02 

STABLE 

3.01E-Ol 
ELEMENT DATA SHEET 

ELEMENT: FRANCIUM 

PARTICLE SIZE: 1.OE+OO tlICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1.00E+OO 

1.00E+OO INGESTION 

PULMONARY 

PARENCHnfA 

2.49E-01 

RATE CONSTANT. 

l!DAYS 

1.00E-1O 

1. OOE+OO CLASS D O.OOE+OO CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMl10N ISOTOPES OF FRANCIUM: MASS NUMBER 

222 

223 

B-790 

HALFLIFE ,DAYS 

1.OOE-02 

1.51E-02 
ELEMENT DATA SHEET 

ELEMENT: RADIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f 1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

5. 14E-Ol 

2.04E-Ol 

2.58E-Ol 

9. 83E-03 

5. 64E-03 

3. 15E-03 

5. 83E-03 

2.00E-Ol INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

5.20E+Ol 

7. 56E-Ol 

1.67E-Ol 

2. 88E-03 

6. llE-04 

1. 88E-04 

7. 76E-05 

O.OOE+OO CLASS D 2.00E-Ol CLASS W O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 5.00E-02 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 9.S0E-Ol 

THE COMMON ISOTOPES OF RADIUM: MASS NUMBER 

223 

224 

225 

226 

227 

228 

B-791 

HALFLIFE, DAYS 

1.14E+Ol 

3. 66E+OO 

1.48E+Ol 

S.84E+05 

2. 93E-02 

2.10E+03 
ELEMENT DATA SHEET 

. ELEMENT: ACTINIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.50E-Ol 

4.50E-Ol 

3.50E-04 

9.97E-02 

1.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

1.90E-05 

4. 75E-05 

1.00E-I0 

2.77E+00 

1.00E-03 CLASS D 1.00E-03 CLASS W 1.00E-03 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF ACTINIUM: MASS NUMBER 

224 

225 

226 

227 

B-792 

HALFLIFE, DAYS 

1.21E-Ol 

1.00E+Ol 

1.21E+00 

7. 95E+03 
ELEMENT DATA SHEET 

ELEMENT: THORIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-OI 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

7.00E-0l 

4.00E-02 

1.60E-OI 

1.00E-OI 

FRACTION FROM GI TRACT TO BLOOD (f 1): 2.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

8. 66E-05 

9.90E-04 

9.90E-04 

1. 39E+00 

O.OOE+OO CLASS D 2.00E-04 CLASS W 2.00E-04 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 1.0E+00 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 1.0E-02 

THE COMMON ISOTOPES OF THORIUM: MASS NUMBER 

226 

227 

228 

229 

230 

231 

232 

234 

B-793 

HALFLIFE. DAYS 

2.l5E-02 

l.87E+Ol 

6. 98E+02 

2. 68E+06 

2.81E+07 

1.06E+00 

5.13E+l2 

2. 41E+Ol 
ELEMENT DATA SHEET 

ELEMENT: PROTACTINIUM 

PARTICLE SIZE: 1.0E+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-0l 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (£1): 

------------------------------------

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.00E-0l 

1.09E-Ol 

6.lOE-02 

4.30E-0l 

1.00E-03 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

l/DAYS 

1.90E-05 

6. 93E-02 

1. 16E-02 

2. 77E+OO 

O.OOE+OO CLASS D 1.00E-03 CLASS W 1.00E-03 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF PROTACTINIUM: MASS NUMBER 

227 

228 

230 

231 

232 

233 

234 

B-794 

HALFLIFE, DAYS 

2. 66E-02 

9. 17E-Ol 

1. 74E+Ol 

1.20E+07 

1.31E+00 

2.70E+Ol 

2.79E-Ol 
ELEMENT DATA SHEET 

ELEMENT: URANIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.lOE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

2.00E-Ol 

2.30E-02 

2.40E-Ol 

1.04E-03 

5. 36E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

3.47E-02 

1. 39E-04 

1. 16E-Ol 

4. 62E-04 

2. 27E+00 

FRACTION FROM GI TRACT TO BLOOD (f 1): 5.00E-02 INGESTION 

5.00E-02 CLASS D 5.00E-02 CLASS W 2.00E-03 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 1.0E+00 

THE COMMON ISOTOPES OF URANIUM: MASS NUMBER HALFLIFE, DAYS 

~-~~---~-------------------- ----------- -_ ... _---------

230 2.08E+Ol 

231 4.20E+00 

232 2. 63E+04 

233 5. 79E+07 

234 8.92E+07 

235 2. 57E+11 

236 8. 55E+09 

237 6. 75E+00 

B-795 
ELEMENT DATA SHEET 

ELEMENT: NEPTUNIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.l0E-Ol 

SYSTEMIC RETENTION: 

FRACTION FROM GI TRACT TO BLOOD (f l ): 

O.OOE+OO CLASS D 1.OOE-02 CLASS W 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.50E-Ol 

4.50E-Ol 

9. 97E-02 

3.50E-04 

1.OOE-02 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT t 

l/DAYS 

4. 75E-05 

1.90E-05 

2.77E+OO 

1.OOE-lO 

O.OOE+OO CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 5.00E-Ol 

FRACTION OF SlSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 5.00E-Ol 

THE COMMON ISOTOPES OF NEPTUNIUM: MASS NUMBER 

232 

233 

234 

235 

236 

236 

237 

238 

B-796 

HALFLIFE t DAYS 

1.02E-02 

2.5lE-02 

4.40E+OO 

3. 96E+02 

4.20E+07 

9. 38E-Ol 

7.8lE+08 

2.l2E+OO 
ELEMENT DATA SHEET 

ELEMENT: PLUTONIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

1. 59E-02 

1.01E-02 

4. 19E-02 

9. 32E-Ol 

PULMONARY 

PARENCHYMA 

2. 49E-Ol 

RATE CONSTANT, 

I/DAYS 

5. 59E-Ol 

4. 41E-02 

3. 18E-03 

2. 84E-05 

FRACTION FROM GI TRACT TO BLOOD (f1): 1.00E-04 INGESTION 

------~---------~--~-----------

O.OOE+OO CLASS D 1.00E-04 CLASS W 1.00E-05 CLASS Y 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH URINE (fu ): 5.40E-Ol 

FRACTION OF SYSTEMIC UPTAKE EXCRETED THROUGH FECES (ff): 4.60E-Ol 

THE COMMON ISOTOPES OF PLUTONIUM: 

----------------------------~~ 

MASS NUMBER 

234 

235 

236 

237 

238 

239 

240 

241 

B-797 

HALFLIFE, DAYS 

3. 67E-Ol 

1.76E-02 

1.04E+03 

4. 53E+Ol 

3.20E+04 

8.78E+06 

2. 39E+06 

5. 26E+03 
ELEMENT DATA SHEET 

ELEMENT: AMERICIUM 

PARTICLE SIZE: 1.0E+00 MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.1OE-01 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.50E-01 

4.50E-01 

9. 97E-02 

3.50E-04 

FRACTION FROM GI TRACT TO BLOOD (£1): 5.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2. 49E-01 

RATE CONSTANT, 

1/DAYS 

4. 75E-05 

1.90E-05 

2. 77E+00 

1.00E-1O 

O.OOE+OO CLASS D 5.00E-04 CLASS W 5.00E-04 CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF AMERICIUM: MASS NUMBER 

237 

238 

239 

240 

241 

242 

242m 

243 

244 

244m 

B-798 

HALFLIFE, DAYS 

5.07E-02 

6. 81E-02 

4. 96E-01 

2. 12E+00 

1. 58E+05 

6. 68E-01 

5. 55E+04 

2. 69E+06 

4.21E-01 

1.81E-02 
ELEMENT DATA SHEET 

ELEMENT: CURIUM 

PARTICLE SIZE: 1.OE+OO MICRONS 

LUNG DEPOSITION: NASAL 

--------------- PASSAGES 

3.10E-Ol 

SYSTEMIC RETENTION: 

TRACHEA AND 

BRONCHIAL TREE 

8.00E-02 

COEFFICIENT 

4.50E-Ol 

4.50E-Ol 

9.97E-02 

3.50E-04 

FRACTION FROM GI TRACT TO BLOOD (f 1): 5.00E-04 INGESTION 

PULMONARY 

PARENCHYMA 

2.49E-Ol 

RATE CONSTANT, 

l/DAYS 

4.75E-05 

1.90E-05 

2. 77E+OO 

1.00E-I0 

O.OOE+OO CLASS D 5.00E-04 CLASS W O.OOE+OO CLASS Y 

EXCRETION PATHWAYS ARE NOT DEFINED: 

THE COMMON ISOTOPES OF CURIUM: MASS NUMBER 

238 

240 

241 

242 

243 

244 

245 

246 

B-799 

HALFLIFE, DAYS 

1.00E-Ol 

2.70E+Ol 

3. 28E+Ol 

1.63E+02 

1.04E+04 

6. 61E+03 

3. lOE +0 6 

1.73E+06 

8. RETENTION FRACTIONS FOil SIZE DISTIllBUTIONS 0'l'HBIl 1.'IIAN 1 AMAD 

After a short time post single intake, the following approximate relati 

exists between the total body IRFs for different aerosol sizes between O. 

10 llm. 

lRF(AMAD) 

IRE (1 pm) 

where: 

IRF(AMAD) 

lRF (IlJIIl) 

1: [fN

_

P x HSOTWT x DN_P(AMAD) 

T l:HSOTWT DN_P( 1 llm) 

T 

+ f T-B x HSOTWT x DT_B(AMAD) 

l:HSOTWT DT-B (1 llm) 

T 

+ fp x HSOTWT x Dp(AMAD) (B.8.I) 

EHSOTWT Dp(l llm) 

T 

= total body intake retention fraction for inhalation of 

Class D, W or Y compounds for AMAD of interest, 

= total body intake retention fraction for inhala 

1 llM AMAD aerosols, and these IRFs are given in 

Appendix B, 

= the fraction of committed dose equivalent in the tissue 

T resulting from deposition in the N-P, T-B and P 

regions respectively, 

= the weighted committed dose equivalent in tissue T per 

unit intake, 

= regional deposition fractions for an aerosol entering 

the respiratory system. 

The time at which equation B.B.I is valid is a time post intake which is 

variable between classes of compounds. For Class D, the time at which the 

equation yields satisfactory results is less than I day, for Class W, the time 

is about 7 days post intake and for Class Y, the time is about 9 days post 

intake. Values for f N_P' f T-B, fp and HSOTWT' which are to be used in 

equation B.8.1, are listed in Supplements to ICRP Publication 30 (ICRP79). 

Values for DN_P' DT-B and Dp are given in Table B.S.I. 

B-SOO 
;, I 

, " .' ' 
Table B.8.1 Regional Deposition Fractions for Aerosols with AMADs Between 

0.2 and 10 pm. 

Aerosol AMAD, Pm 

0.2 0.5 0.7 1 

DN_

P 4. 98E-02 1.6lE-0l 2. 27E-Ol 3.lOE-01 

DT- B 8.00E-02 8.00E-02 8.00E-02 8.00E-02 

Dp 5.00E-Ol 3.50E-Ol 2. 99E-Ol 1.67E-01 

Total 

Deposition 6.30E-Ol 5.9lE-01 6.06E-Ol 6. 68E-Ol 

Aerosol AMAD, pm 

2 5 7 10 

DN_

P 5.00E-Ol 7. 44E-Ol 8.l4E-01 8. 75E-Ol 

DT- B 8.00E-02 8.00E-02 8.00E-02 8.00E-02 

Dp 1.67E-01 8.80E-02 6.74E-02 4. 98E-02 

Total 

Deposition 6. 68E-Ol 9.l2E-01 9.6lE-Ol I.OOE-OO 

A plot of total body IRF versus time post intake for Class D Cs-137, Class W 

Co-60 and Class Y Pu-239 is given as Figure B.8.l. The values for IRFs were 

computed for different aerosol sizes as described in Section 2 and not from 

equation B.8.I. After some time post intake, the curves for a given nuclide 

for different AMADs are parallel, and it is at these times that equation B.8.l 

applies. For example, at 100 days post intake of 0.2 um AMAD Co-60, the IRF 

obtained from equation B.8.I. is 9.7E-02 for the total body. The IRF from 

computation in the manner described in Section 2 is 1.OE-01. The approximate 

method relies on a summation over all tissues, but only those tissues contributing greater than 10% to the effective dose equivalent are listed in ICRP 

Publication 30 Supplements. Thus, the IRFs derived from equation B.8.1 are a 

few % less than the IRFs derived by the method described in Section 2. 

B-801 
>-

Q 

o 

,IX) 

..J 

0« 

.... 

~ 

IO-ILCs -137 

CLASS 0 

CO-so CLASS W 

Co-so CLASS W 

Co-so CLASS W 

Figure B.8.1 Inhalation intake retention functions for 0.2, 

1 and 10 micrometer aerosols of Class D Cs-137, 

Class W Co-60 and Class Y Pu-239 

B-802 
9. RETERTIOR FRACTIONS FOil KULTIPLE AND CONTINUOUS IR"l.AXES OF SELECTED 

BUCLIDES 

Single intake tabulations may also be applied to prolonged or continuous 

intake satisfactorily_ In practice, a worker may receive repeated exposures 

to the same radionuclide during a controlled period. If these intakes are 

separated by not less than three or four effective half-Hfes, each one can be 

treated as a single intake, evaluated with the help of these tabulations, and 

the individual exposures added together to estimate total dose. If they are 

not so separated, they should be treated as a prolonged or continuous 

intake. Although there are special methods (Sk81) to estimate prolonged and 

continuous intake, it may be done by using the relevant Intake Retention 

Fraction for single intake which is given in this manual. Estimates of intake 

obtained by either method will differ by only a few percent. 

A model adopted by Muller et al. (Mu66) projects a total intake of A ~Ci 

evenly distributed over T days, that is, an average of A/T ).lei per day. This 

is a reasonable model for irregularly repeated intakes of different magnitudes. As long as the intakes are not asymmetrically distributed in size and 

time, then the IRFs which are derived by using Muller's approximation will be 

reasonably accurate. 

The expression which describes the expected content (q(t» of a radionuclide 

for constant continuous intake is given by: 

(q(t » = A 

T 

t 

! 

o 

A t 

(q(t» ... if I 

t-T 

where: 

r(u) du for t(T 

r(u) du for t>T 

-

u = variable time between integration limits, 

(B.9.1) 

(B.9.2) 

r(u)'" intake retention fraction in compartment or whole body fora 

single intake of radionuclide, which can be found in this manual, 

q(t)... amount or activity of radionuclide in question in the compartment 

or whole body at time t post the onset of intake, 

A = total amount of activity intake during the period of I. 

The equations B.9.I and B.9.2 are suitable for estimating the intake based on 

the in vitro measurements by substituting the fraction of intake for 24-hour 

excretion or accumulated excretion in place of the retention fraction for 

compartments or the whole "body. 

B-803 
The single intake retention functions r(u) in this report all can be expressed 

as a sum of exponential terms with constant coefficients (Sk83): 

n 

r(u) = 1: 

j=l 

where k. = K. + A = total removal rate constant for compartment j. When this 

expresston fo~ r(u) is substituted into the expression on the right hand side 

of equations B.9.l and B.9.2, the expected contents <q(t» are respectively 

expressed: 

n 

<q (t» _ A 1: Cj (l-e -kjt) --T j=l kj 

(B.9.3) 

for t<T, and 

n (t-T) 

<q (t» _A 1: Cj (l-e -kjT) e-kj , --T j=1 kj 

(B.9.4) 

for t>T. 

These expressions can be used to define a continuous intake retention function 

pet), which gives the fraction of the total intake expected to be present at 

times t post the onset of continuous intake: pet) = <q(t» / A or pet) = 

<q(t»/(A/T)t, which shows that the continuous intake retention function pet) 

can be obtained from the single intake retention functon by simply replacing 

e-kjt in equation 2.5.1 by: 

or by: 

(l-e-kjt) ,for t<T. 

kjt 

In the later case pet) - <q(t»/(At/T), the fraction of the total intake 

present at the end of the intake interval t. 

Except for the case where t<T, these same replacement functions are applicable 

to converting a single intake type incremental excreta function to a 

continuous intake type. Replace e-kjt in the single intake incremental 

excreta function by: 

(l-e -kj T) e -kj T, for t>T+.6t, 

kjT 

or replace e-kjt in the single intake accumulated excreta function by: 

-e -A.6t (l-e -kjT) e -kj (t-.6t-T) (l-e -(kj :-A).6t), 

kjT 

for t>T+At. 

B-804 
, . 

The integration of the equations above also can be obtained by numerical 

methods as follows: 

where: 

h = b-a 

n 

2 

(B.9.5) 

= b, Xi = a + ih, i = the ith increment and 

n = the number of increments. 

As long as one divides the integration region a to b into appropriate increments, the accuracy of the result is good. 

IRF values can be obtained for any time t of interest by interpolating the 

data in the manual. The best method is by plotting as done in Figure B.9.1. 

For example, whole-body counting for person A and urine sampling for person B 

were performed on March 1, 1982, and they showed both workers were internally 

contaminated with cobalt-60. They worked with cobalt-60 from January 5, 1981 

to December 25, 1981. The mode of exposure was assumed to be constant 

continuous inhalation. 

The whole-body counting result was 1.2 E+04 Bq (0.33 pCi), and the urine result 

was 3.4 E+Ol Bq (0.91 nci). In this case, the intake period T is 350 days, and 

the time of interest post onset of intake is 420 days. The integration region 

was divided into seven intervals and each is 50 days. Estimated constant 

continuous IRF values were as follows: 

Table B.9.1. IRFs and Time Post Single Intake 

Time 

Post ItF (Total Body) IRF 24-Hour Urine 

Intake(Days) 

70 7.87 x 10-2 2.17 x 10-4 

120 4.60 x 10-2 1.30 x 10-4 

170 3.05 x 10-2 8.20 x 10-5 

220 2.15 x 10-2 5.25 x 10-5 

270 1.62 10-2 3.40 x 10-5 x 

320 1.33 x 10-2 2.22 x 10-5 

370 1.13 x 10-2 1.40 x 10-5 

420 1.00 x 10-2 1.00 x 10-5 

B-805 
thus, for the total body, 

420 

r r(u) du - 50 x [7.87 + 1.00 + 4.60 + 3.05 + 2.15 + 1.62 + 1.33 + 1.13] x 

70 . 2 

= 9.16, 

and for 24-hour urine 

420 

r r( u) du = 

70 

50 x [21.7 + 1.00 

2 

+ 13.0 + 8.20 + 5.25 + 3.40 + 2.22 + 1.40] x 10-5 

4 -2 = 2.2 x 10 • 

Substituting the whole-body counting data into equation B.9.2 yields: 

420 

1.2 E04 Bq :I!. r r(u) du = 

T 

70 

A (9.16) 

350 

Thus, the intake A is 4.7 E+05 Bq (12.6 ~Ci). 

Substituting the one-day urine data into equation B.9.2. yields: 

3.4 EOI Bq 

420 

= !. r r(n) 

T 

70 

Thus, the intake is 5.3 E+05 Bq (14.2 UCi). 

If exact analytical solutions are used for this example rather than numerical 

integration methods, the IRF for the total body is 2.58 E-02 and the IRF for a 

24-hour urinary sample is 6.19 E-05. Thus, for a 350 day interval of 

continuous intake followed by a 70 day interval of no exposure, the intake 

based on whole-body counting is 4.7 E+05 Bq (12.8 ~Ci) and for a urinary 

sample measurement, the intake is estimated to be 5.4 E+05 Bq (14.7 ~Ci). 

These values compare closely to values obtained by using the numerical 

integration technique given above. 

B-806 
24 HOUR 

URINE IRF 

TOTAL BODY 

IRF 

-3~ __ ~ ______ ~~~~ ____ ~~~~ __ ~~10-5 

10 10 100 1000 

TIME POST INTAKE, days 

FIGURE B.9.1 Total Body and 24-hour Urine IRF for 

Co-60 Class W aerosols. 

B-B07 
10. BIBLIOGRAPHY 

Mu66 Muller. J •• Klener. V •• Tuscany. R., Thomas. J., Brezikova. D., and 

Houskova, M., 1966, "Study of Internal Contamination with Strontium90 and Radium-226 In Man In Relation to Clinical Findings", Health 

Physics, 12. pp. 993-1006. 

Sk83 Skrable, K. W., 1983, "Retention Functions and Their Applications to 

Bioassay and Internal Dose Estimation," manual and presentation at 

Health Physics Society 1983 Summer School on Internal Radiation 

Dosimetry, June 12 - 17. 1983, University of Maryland at Baltimore 

County, Catonsville, Maryland. 

B~08 
60s-a 

. " . , '." . 

a: XIQftc1dV OJ. XgOlO 'IT.)IJ.gOBcl''lY -II 
Actinium 

class D lRFs, B-156 

class W lRFs, B-325 

class Y lRFs, H-439 

ingestion lRFs, B-674 

class D lRFs, B-18 

class W lRFs, B-170 

ingestion lRFs, H-477 

A.:!ricium 

class W lRFs, B-353 

class Y lRFs, B-463 

ingestion lRFs, B-702 

Arsenic 

class W lRFs, B-220 

ingestion lRFs, B-539 

Astatine 

class D lRFs, B-153 

class W lRFs, B-319 

Barium 

class D lRFs, B-113 

ingestion lRFs, B-594 

Beryllium 

class W lRFs, B-165 

class Y lRFs, B-360 

ingestion lRFs, B-468 

BisllUtb 

class D lRFs, B-149 

class W lRFs, B-315 

Bromine : 

class D lRFs, B-66 

class W lRFs, B-224 

ingestion lRFs, B-543 

B-81O 

Cadmium 

class D lRFs, B-90 

class W lRFs, B-248 

class Y lRFs, B-409 

ingestion lRFs, B-575 

Calcium 

class W lRFs, B-186 

ingestion lRFs, B-497 

Carbon (Monoxide and Dioxide) 

intake lRFs, B-709 

Cerium 

class W lRFs, B-259 

class Y lRFs, B-411 

ingestion lRFs, B-602 

Cesium 

class D lRFs, B-I09 

Chlorine 

class D lRFs, B-30 

class W IRFs, B-182 

ingestion lRFs, B-489 

Chromium 

class D lRFs, B-42 

class W lRFs, B-196 

class Y lRFs, B-369 

ingestion lRFs, B-507 

Cobalt 

class W lRFs, B-208 

class Y lRFs, B-373 

ingestion lRFs, B-521 

Copper 

class D lRFs, B-58 

class W lRFs, B-216 

class Y lRFs, B-379 

ingestion lRFs, B-529 
Curium 

class W IRFs, B-3S7 

Dysprosium 

class W IRFs, B-28S 

ingestion IRFs, B-628 

Erbium 

class W IRFs, B-289 

ingestion IRFs, B-632 

Europium 

class W IRFs, B-27S 

ingestion IRFs, B-618 

Pluorine 

.class D IRFs, B-13 

class W IRFs, B-167 

class Y IRFs, B-362 

ingestion IRFs, B-472 

Francium 

class D IRFs, B-ISS 

Gadolinium 

class D IRFs, B-121 

class W IRFs, B-281 

ingestion IRFs, B-624 

Galliua 

class D IRFs, B-60 

class W IRFs, B-218 

ingestion IRFs, B-S3S 

GerEDium 

Gold 

class D IRFs, B-62 

ingestion IRFs, B-S37 

class D IRFs, .B-139 

class W IRFs, B-313 

. class Y IRFs, B-437 

ingestion IRFs, B-6S8 

B-811 

Hafnium 

class D IRFs, B~123 

class W IRFs, B-297 

ingestio~ IRFs, B-638 

Holmium 

class W IRFs, B-287 

ingestion IRFs, B-630 

Hydrogen (Water Vapor) 

intake IRFs, B-711 

Indium 

class D IRFs, B-92 

class W IRFs, B-2S0 

Iodine 

class D IRFs, B-97 

ingestion IRFs, B-S81 

Iridium 

Iron 

class D IRFs, B-133 

class W IRFs, B-309 

class Y IRFs, B-433 

ingestion IRFs, B-6S2 

class D IRFs, B-SO 

class W IRFs, B-204 

ingestion IRFs, B-SIS 

Lanthanum 

Lead 

class D IRFs, B-117 

class W IRFs, B-2SS 

ingestion IRFs, B-S98 

class D IRFs, .B-147 

ingestion IRFs, B-666 

Lutetium 

class W IRFs, B-29S 

class Y IRFs, B-42S 

ingestion IRFs, B-636 
~ ., 

i 

~: 

IlagnesiUlll 

" c class D IREs, B-16 

(,,_; class W IRFs ~ B-168 

.: .;.~.~ ~·."tn~estion IREs, B-475 

Kanganese 

~lass D IRFs, B-46 , .. . .. _ class W IRFs, B-200 

n··~:~~·-;\i~geS~ion IRFs, B-:5.11 

Mercury 

class D IREs, B-141 

';:,~!:', ~,p.gestion IRFs, 8-660 

class D IRFs, B-80 

class Y IRFs, B-399 

i~g~stion IRFs, 8-563 

. lIeocIYrrlull. 

class W IRFs, B-267 

class Y IRFs, B-419 

i'ngestion IRFs, B-610 

Neptun:lum 

, ,~ :; 

class WIREs, B-343 

ingestion IRFs, B-692 

class D IRFs, B-56 

class W IRFs, B-214 

ingestion IRFs, B-527 

Riobiu. 

class W IRFs~ B-234 

class Y IRFs, B-395 

ingestion IRFs, B-559 

class D IRFs,' B-131 

classY. JRFs, 8-431 

B-812 

Palladium. 

class D IRFs, B-86 

class WIREs, B-244 

class Y I~s, B-405 

ingestion IRFs, B-57 

Phosphorus 

class D IRFs, B-22 

class W IRFs, 8-174 

ingestion IRFs, 8-481 

Platinllll 

class D IRFs, B-137 

ingestion IRFs, 8-656 

Pluton:lUlll 

class W IRFs, B-345 

class Y IRFs, B-455 

ingestion IRFs, 8-694 

Polon:lua 

class D IRFs, B-151 

class W IRFs, B-317 

ingestion IRFs, 

Potassium 

class D IRFs, B-34 

ingestion IRFs, B-493 

PraseodymiUlll 

class W IRFs, 8-265 

class Y IRFs, B-417 

ingestion IRFs, B-608 

Promethium. 

class W IRFs, B-269 

class Y IRFs, B-421 

ingestion IRFs, B-612 

Protactin:lull. 

class W IRFs, 8-335 

class Y IRFs, 8-449 

ingestion IRFs, B-684 
Iladium 

class W IRFs, B-321 

Rhenium 

class D IRFs, B-12~ 

ingestion IRFs, B-648 

Bhodium 

class W IRFs, B-242 

class Y IRFs, B-403 

ingestion IRFs, B-569 

Rubidium 

class D IRFs, B-70 

ingestion IRFs, B-547 

Ruthenium 

class D IRFs, B-84 

class W IRFs, B-305 

class Y IRFs, B-401 

ingestion IRFs, B-567 

Samarium 

class W IRFs, B-271 

ingestion IRFs, B-614 

Scandium 

class YIRFs, B-365 

Selenium 

class D IRFs, B-64 

class W IRFs, B-222 

ingestion IRFs, B-541 

Silicon 

class D IRFs, B-20 

class W IRFs, B-172 

class Y IRFs, B-363 

ingestion IRFs, B-479 

B-813 

Silver 

class D I~s.~ B-88 

class Y IRFs', B-407 

ingesti6n'tRFs, B-573 

Sodium 

class D IRFs, B-14 

class W 'IRFs ~ B-246 

ingestion IUs, B-473 

Strontium 

class D IRFs~ B-72 

class Y IRFs, B-385 

ingestion IRFs, ~T549 

Sulfur 

class D IRFs, B-26 

class W IRF~, B-178 

ingestion IRFs, B-485 i' ,II""': 

class W IRFs, B-301 , class Y IRFs, B-427 

ingestion IRFs, B-642 

Technetium , 

class D IRFs, B-82 

class W IRFs, B-~38 

ingestion IRFs~ B-565 

Tellurium 

class D IRFs, B-95 

class W IRFs, ~-Z53 

ingestion IRFs,' :S-579 

Terbium 

class W IRFs, B-283 

ingestion IRFs, B-626 

f.J ,:_ 

'Dlallium 

, fl . 

c1as~ 'D IRFs, B-143 

ingestion IRFs, B-662 
:'ORM:I:15 

.1 

U,S, NUCI.EAR IUGULATORV COMMISSION 

;M 110', 

1,3202 BIBLIOGRAPHIC DATA SHEET 

. INSTRUCTIONS ON THe REVERSE 

ITlS AND 5U8T1TLE 

INTERPRETATION OF BIOASSAY MEASUREMENTS 

IUTHORIS! alter -Joyce LanC1ID.ann L~pszte:ln 

Edward T. Lessard~ Xia Yihua~ Kenneth W. Skrable~ 

George E. Chabot, Clayton S. French, Thomas R. Lab~~~a 

John R. Johnson, Darrell R. Fisher, Richard Belanger. PERfORMING ORGANIZATION NAME ANO MA'LING ADDRESS /lnC/.rI.l,,, C"tlI) 

Brookhaven National Laboratory 

. Safety & Evnironmental Protection Department 

Bldg. 535 A 

TTnf-"..... 11.1V 11 Q 7 ':I 

NRC Division of Regulatory Applications 

2. SUPPLEMENTARY NOTES 

NUREG/CR-4884 

BNL-NUREG-5206,~ .... , ,~. (:o;!!" 

• a! T£ REPORT COMPLETED 

MONTH I 

JUNE ~;: ' :': ,;.: .~ .;~f1" 1987 

VEAR 

1987 

B. PROJIlCTIT"'SK,WORK UI)IIT:"t.UMSER J..' •• f;l, 

9. FIN OR GR ... NT NUMBER ':~ 

.Fin. A-3289 

I h. TYPE OF REPOAT 

~l'i13J!f: ::- ~' • 

Final 

. I: ~ .1 

This is a comprehensive manual describing how to cOrllpute intakes from both in-vivo 

and in-vitro bioassay measurements. To date, inter~retationgof intake have been inistent, particularly in the early phases after an accidental intake. This manual 

aimed at completely describing a consistent approach and instructing·others on how 

to compute intakes and committed organ dose equivalents. Tables for the interpretation of bioassay res.ults are compiled for several r'liurtdred radioril.i.cFides. Measurements 

which employ a whole-body counter, a thyroid counter ,'a lung count-e:t', or measurements 

on excreta can be converted into estimates of intake"based on the ·:tables presented in 

the appendices. The values in the tables were de t'emined' bY"-usihg lung, gastrointestinal tract and systemic retention models published by the International Commission 

on Radiological Protection (ICRP79). In a few cases, pseudo-retent.ion functions, 

organ retention functions, and excretion functions were used to generate the tabulated 

values. The biological and radiological input para'ttieters are included in an appendix, 

and a description of the mathematical approach that wa.s used to derive the tabulated 

data is included in the methods section. Calculati<fus'for various particle sizes 

are addressed along with methods to interpret multiple or continuous exposures. 

Examples of use are based on actual bioassay measurements fOllowingi acc:fdEmtal intakes, 

including tritium, Mn-54, Co-60, Sr-90, Nb-95, radioiodines, Cs-137, Ce-141, Ce-144, 

U-233, U-Nat, and Am-241. .~ \.'C, ie',,;; 'c:.L; 

,) ... :~ .. ~~~"~ -::: 

!. OOCUMENT ANAL YSIS - •. KEYWOROS/OESCRIPTORS 

1>. 10ENTIFIERS/OPEN-ENOEa TERMS 

15 ... VA'I. ... SI LITY 

STATEMENT 

"m .... ,;.l 'Unlimite~ 

""".1 2 'i;~. ., ~B ['. " 

\ :~::,U , J .r:: t",' ;'Fl" 

III SECURITYCI.ASSll'lfATION 

ITh"Hf.1 Unclassified 

, rlt" 4t/HNfJ 

Unclassified 

11 NUMBiR OF PAGES 

814 

'8 PRICI 

-c. u.s. GOVERNMENT PAINTING OFFlCE: 1987- 7 1 3 - 7 0 1 , 0