UNITED STATES ENVIRONMENTAL PROTECTION AGENCY 

WASHINGTON, D.C. 20460 

MEMORANDUM 

DATE: December 19, 2012 

OFFICE OF CHEMICAL SAFETY 

AND POLLUTION PREVENTION 

SUBJECT: Flumioxazin: Acute and Chronic Dietary (Food and Water) Exposure 

and Risk Assessments for the Proposed Uses on Artichoke, Cabbage, 

Olive, Pomegranate, and Prickly Pear Cactus. 

PC Code: 129034 

Decision No.: 4508 10 

Petition No.: I F7886 

DP Barcode: 0406069 

Registration No.: I 00-727 

Regulatory Action: Section 3 

Registration 

Risk Assessment Type: Dietary 

TXRNo.: NA 

Case No.: NA 

CAS No.: 103361-09-7 

MRIDNo.: NA 40 CFR: 180.568 

REVIEWER: Richard Duncan, Associate Toxicologist 

Department of Pesticide Regulation 

California Environmental Protection Agency 

Sheila P~~r, Chemist ~~ \£,~ Risk Assessment Branch VI 

Health Effects Division (7509P) 

THROUGH: 

Dietary 

Seyed Tadayon, 

Exposure 

Chemist 

SAC (7509pf 

~~ 

Christine li ng:~~ Acting Branch Chief /J / ~ Risk Assessment Branch VI {/?#/-~-~-- Health Effects Division (7509P) 

TO: Andrew Ertman, Barbara Madden RM05 

Risk Integration, Minor Use, and Emergency Response Branch 

Registration Division (7505P) 

This document was originally prepared by California Department of Pesticide Regulation 

(1 001 I Street, Sacramento, CA 95812; submitted 0811712012) 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 2 of 17

Executive Summary

At the request of the Registration Division, an acute and chronic dietary risk assessment 

for flumioxazin was conducted using the Dietary Exposure Evaluation Model DEEMFCID, Version 3.16 which uses food consumption data from the U.S. Department of 

Agriculture’s National Health and Nutrition Examination Survey, What We Eat in 

America, (NHANES/WWEIA) from 2003-2008. This analysis was performed to estimate

the acute and chronic dietary (food and drinking water) risk resulting from current and 

new uses of flumioxazin on artichoke, cabbage, olive, pomegranate, and prickly pear 

cactus.

Acute Dietary (Food and Drinking Water) Exposure Results and Characterization

An unrefined, acute dietary exposure assessment using tolerance levels, processing 

factors, and assuming 100% crop treated (CT) for the proposed commodities was 

conducted for the general U.S. population and various population subgroups. The 

estimated drinking water concentration of flumioxazin was provided by the 

Environmental Fate and Effects Division (EFED) and incorporated directly into the acute 

assessment. An estimated environmental concentrations (EECs) for flumioxazin and its 

major degradates (482-HA and APF) under the use as an aquatic herbicide of 400 ppb 

was estimated for acute exposure.

There were no appropriate toxicological effects attributable to a single exposure (dose) 

for the general population or any other population subgroups except females 13-49 years 

old; therefore, these population subgroups were not included in this assessment. For food 

and drinking water, the acute dietary risk estimate is below HED’s level of concern 

(<100% of the acute population adjusted dose (aPAD)) at the 95th percentile of exposure. 

The acute dietary exposure estimate for females 13-49 years old is 0.022607 mg/kg/day 

(75% of the aPAD).

Chronic Dietary (Food and Drinking Water) Exposure Results and Characterization

The chronic dietary exposure and risk estimates are conservative since they assume that 

100% of crops are treated, processing factors, and that the residues are present at the 

tolerance levels. The EECs for flumioxazin and its major degradates (482-HA and APF) 

under the use as an aquatic herbicide is 142 ppb. Combined chronic dietary exposure 

estimates for food and drinking water are well below HED’s level of concern. Using the 

DEEM-FCID software, dietary exposure is estimated at 0.003932 mg/kg/day for the 

general U.S. population, which is equivalent to 20% of the chronic Population Adjusted 

Dose (cPAD), and 0.008753 mg/kg/day, equivalent to 44% of the cPAD for all infants (< 

1year old), the population subgroup with the highest estimated chronic dietary exposure 

to flumioxazin.

Cancer Dietary (Food and Drinking Water) Exposure Results and Characterization
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 3 of 17

Flumioxazin is classified as a “Not likely to be carcinogenic to humans.” Therefore, a 

cancer dietary exposure analysis is not required. 

I. Introduction

Dietary risk assessment incorporates both exposure and toxicity of a given pesticide. 

For acute and chronic assessments, the risk is expressed as a percentage of a maximum 

acceptable dose. This is the population adjusted dose (PAD), which HED has 

concluded will result in no unreasonable adverse health effects. The PAD is the 

Reference Dose (RfD) divided by the FQPA Safety Factor. Dietary risk is expressed as 

a percentage of the PAD. For acute and non-cancer chronic exposures, HED is 

concerned when estimated dietary risk exceeds 100% of the PAD. References which 

discuss the acute and chronic risk assessments in more detail are available on the 

EPA/pesticides web site: “Available Information on Assessing Exposure from 

Pesticides, A User’s Guide”, 6/21/2000, web link: 

http://www.epa.gov/fedrgstr/EPA-PEST/2000/July/Day-12/6061.pdf; or see SOP 99.6 

(8/20/99).

The most recent dietary risk assessment for flumioxazin was conducted by S. Piper, 

DP#401806, 08/08/2012.

II. Residue Information

Flumioxazin belongs to the N-phenylphthalimide class of herbicides (Group 14) and is 

currently registered for pre- and post-emergence applications on a variety of fruit, 

vegetable, and field crops for the control of susceptible weeds. Tolerances are currently 

established for residues of the herbicide flumioxazin in/on various plant commodities, at 

levels ranging from 0.02 to 8.0 ppm (as listed in e-CFR 40 §180.568[a], updated August, 

2012).

The residue of concern for both the tolerance expression and risk assessment in plants is 

flumioxazin. No livestock tolerances have been established. A tolerance for combined 

residues of flumioxazin and its metabolites APF (3-oxo-4-prop-2ynyl-6-amino-7-fluoro3,4-dihydro-1,4-benzoxazin) and 482-HA (N-(7-fluoro-3,4-dihdyro-3-oxo-4-prop-2-ynyl2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1-carboxamide-2-carboxylic acid) in freshwater 

fish.

The proposed use and the submitted data support the following tolerances based on the 

OECD tolerance calculation for residues of flumioxazin in/on the following commodities:

Artichoke.................................................................................................... 0.02 ppm

Cabbage...................................................................................................... 0.02 ppm

Olive........................................................................................................... 0.02 ppm

Pomegranate............................................................................................... 0.02 ppm

Prickly Pear Cactus Fruit ........................................................................... 0.07 ppm

Prickly Pear Cactus Pads ........................................................................... 0.06 ppm
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 4 of 17

DEEM 7.81 processing factors were used for all processed commodities, with the 

exception of tomato which used the empirical processing factor of one. A tomato 

processing factor of 1 is based on an exaggerated (~5x) crop field trial study in which no 

residues were recovered; therefore, a processing study is not required (47005106.der, D. 

Rate, 6/19/07). 100%CT was assumed for all commodities in this assessment. 

III. Drinking Water Data

References: Drinking Water Assessment for a Section 3 New Use for Flumioxazin EndUse Products Chateau WDG and Valor WDG Applications to Agate and Prickly Pear 

Cactus, Olive, Pomegranate, Cabbage, and Artichoke, D398751, Larry Liu, 9/05/2012.

A Tier I screening level drinking water assessment was conducted to support the human 

health risk assessment for the proposed new use for artichoke, cabbage, olive, 

pomegranate, and prickly pear cactus. EFED have indicated that the drinking waters will 

not change from those last used which were based on the aquatic application rates of the 

herbicide since the maximum single application rate for the proposed uses (0.36 lb ai/A) 

is lower than the maximum single application rate (0.38 lb ai/A) used in the previous 

drinking water assessment (D401806, S.Piper, 08/08/12).

The estimated environmental concentrations (EECs) for flumioxazin and the metabolites 

482-HA and APF are the residues of concern in drinking water. In order to be 

conservative, EECs for flumioxazin and its major degradates (482-HA and APF) as a 

result of the use as an aquatic herbicide of 0.400 ppm (peak day-0) for acute exposure 

and of 0.142 ppm (30-days) for chronic exposure were used in the dietary analyses. Table 

1 lists degradate identified and their relative concentrations. Water residues were 

incorporated in the DEEM-FCID into the food categories “water, direct, all sources” and 

“water, indirect, all sources.” The model and its description are available at the EPA 

internet site: http://www.epa.gov/oppefed1/models/water/.

Table 1. EECs (ppb) From the Subsurface Application of Flumioxazin as an 

Aquatic Herbicide

Compound Peak EEC (Day 0)

(ppb)

EEC at Days 30 and 

after (ppb)

Acute Chronic

Flumioxazin 400 10.4

482-HA - 21.6

APF - 110.1

THPA - 88.9

Total EEC1

142.1

1 Total EEC = Sum of Flumioxazin + 482-HA + APF
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 5 of 17

IV. DEEM-FCID Program and Consumption Information

Flumioxazin acute and chronic dietary exposure assessments were conducted using the 

Dietary Exposure Evaluation Model software with the Food Commodity Intake Database 

DEEM-FCID, Version 3.16, which incorporates consumption data from USDA’s 

NHANES/WWEIA. This dietary survey was conducted from 2003 to 2008. The data are 

based on the reported consumption of more than 20,000 individuals over two nonconsecutive survey days. Foods “as consumed” (e.g., apple pie) are linked to EPAdefined food commodities (e.g., apples, peeled fruit - cooked; fresh or N/S; baked; or 

wheat flour - cooked; fresh or N/S, baked) using publicly available recipe translation files 

developed jointly by USDA/ARS and EPA. For chronic exposure assessment, 

consumption data are averaged for the entire U.S. population and within population 

subgroups. However, for acute exposure assessment, consumption data are retained as 

individual consumption events. Based on analysis of the 2003-2008 WWEIA 

consumption data, which took into account dietary patterns and survey respondents, HED 

concluded that it is most appropriate to report risk for the following population 

subgroups: the general U.S. population, all infants (<1 year old), children 1-2, children 3-

5, children 6-12, youth 13-19, adults 20-49, females 13-49, and adults 50+ years old.

For a chronic dietary exposure assessment, an estimate of the residue level in each food 

or food-form (e.g., orange or orange juice) on the food commodity residue list is 

multiplied by the average daily consumption estimate for that food/food form to produce 

a residue intake estimate. The resulting residue intake estimate for each food/food form 

is summed with the residue intake estimates for all other food/food forms on the 

commodity residue list to arrive at the total average estimated exposure. Exposure is 

expressed in mg/kg body weight/day and as a percent of the cPAD. This procedure is 

performed for each population subgroup.

For an acute exposure assessment, individual one-day food consumption data are used on 

an individual-by-individual basis. The reported consumption amounts of each food item 

can be multiplied by a residue point estimate and summed to obtain a total daily pesticide 

exposure for a deterministic exposure assessment, or “matched” in multiple random 

pairings with residue values and then summed in a probabilistic assessment. The 

resulting distribution of exposures is expressed as a percentage of the aPAD on both a 

user (i.e., only those who reported eating relevant commodities/food forms) and a percapita (i.e., those who reported eating the relevant commodities as well as those who did 

not) basis. In accordance with HED policy, per capita exposure and risk are reported for 

analyses performed at all levels of refinement. However, for deterministic assessments, 

any significant differences in user vs. per capita exposure and risk are specifically 

identified and noted in the risk assessment.

V. Toxicological Information

The findings of the flumioxazin risk assessment team, relative to dietary exposure, are 

summarized in Table 2 (below). In accordance with the EPA Draft Guidelines for 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Carcinogen Risk Assessment (July, 1999), flumioxazin was classified as “not likely to be 

carcinogenic to humans.” 

Table 2. Summary of Toxicological Doses and Endpoints for Use in Human Health Dietary

Risk Assessment for Flumioxazin. 

Exposure/

Scenario

Point of 

Departure

Uncertainty/

FQPA Safety 

Factors

RfD, PAD, 

Level of 

Concern 

Study and Toxicological 

Effects

Acute Dietary 

(General 

Population, 

including Infants 

and Children)

No endpoint attributable to a single dose (exposure) was identified in the available 

studies, including the developmental toxicity studies in rats and rabbits. 

Acute Dietary

(Females 13-49 

years of age)

NOAEL = 3 

mg/kg/day

UFA= 10x

UFH= 10x

FQPA SF = 1X

Total UF = 100X

Acute RfD =

NOAEL UF = 

0.03 mg/kg/day

aPAD = 0.03 

mg/kg/day

Oral developmental and 

supplemental prenatal studies 

in the rat. 

LOAEL = 10 mg/kg/day 

based on cardiovascular 

effects (especially ventricular 

septal defects in fetuses).

Chronic Dietary 

(All Populations)

NOAEL = 2 

mg/kg/day

UFA= 10x

UFH= 10x

FQPA SF = 1X

Total UF = 100X

Chronic RfD 

FQPA SF = 

0.02 mg/kg/day

cPAD = 0.02 

mg/kg/day

2-year chronic/carcinogenicity 

study in the rat. 

LOAEL = 18 mg/kg/day 

based on increased chronic 

nephropathy in males, and 

decreased hematological 

parameters in females (Hgb, 

MCV, MCH, and MCHC). 

Cancer (oral, dermal, inhalation) Classification: “Not likely to be Carcinogenic to Humans” based on 

the lack of carcinogenicity in a 2-year rat study, an 18-month mouse 

study, and a battery of mutagenic studies. 

Point of Departure (POD) = A data point or an estimated point that is derived from observed dose-response data and 

used to mark the beginning of extrapolation to determine risk associated with lower environmentally relevant human 

exposures. NOAEL = no observed adverse effect level. LOAEL = lowest observed adverse effect level. UF = 

uncertainty factor. UFA = extrapolation from animal to human (intraspecies). UFH = potential variation in sensitivity 

among members of the human population (interspecies). UFL = use of a LOAEL to extrapolate a NOAEL. UFS = use 

of a short-term study for long-term risk assessment. UFDB = to account for the absence of key data (i.e., lack of a 

critical study). FQPA SF = FQPA Safety Factor. PAD = population adjusted dose (a = acute, c = chronic). RfD = 

reference dose.

VI. Results/Discussion 

As stated above, for acute or chronic dietary assessments, HED is concerned when 

dietary risk exceeds 100% of the PAD. The DEEM-FCID analyses estimate the dietary 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 7 of 17

exposure of the US population and various population subgroups. The results reported in 

Table 3 (below) are for the general US population (total), all infants <1, children 1-2, 

children 3-5, children 6-12, youths 13-19, females 13-49, adults 20-49, and adults 50+ for 

chronic exposure and females 13-49 for acute exposure. 

Results of Acute Dietary Exposure Analysis

Flumioxazin acute dietary (food + water) exposure estimates using the DEEM-FCID

software are below HED’s level of concern for females 13-49. The acute dietary 

exposure for the females, 13-49 years old, utilized 75% of the aPAD at the 95th

percentile.

Results of Chronic Dietary Exposure Analysis

Flumioxazin chronic dietary (food + water) exposure estimates using the DEEM-FCID 

software are below HED’s level of concern for the U.S. population and each of the 

population subgroups. Chronic dietary exposure utilized 20% of the cPAD for the U.S. 

population. The chronic dietary exposure for the highest reported exposed population 

subgroup, all infants (<1 year old), was 44% of the cPAD.

Table 3. Summary of Dietary Exposure and Risk for Flumioxazin. 

Population Subgroup1

DEEM Acute Dietary 

Analysis, 95th Percentile

DEEM Chronic Dietary Analysis

aPAD 

(mg/kg)

Exposure 

(mg/kg/day)

% 

aPAD

cPAD 

(mg/kg/day)

Exposure 

(mg/kg/day)

% 

cPAD

General U.S. Population

NA 2

0.02 0.003932 20

All Infants (< 1 year 

old)

0.02 0.008753 44

Children 1-2 years old 0.02 0.006811 34

Children 3-5 years old 0.02 0.005959 30

Children 6-12 years old 0.02 0.004253 21

Youth 13-19 years old 0.02 0.003116 16

Adults 20-49 years old 0.02 0.003715 19

Adults 50+ years old 0.02 0.003633 18

Females 13-49 years old 0.03 0.022607 75 0.02 0.003692 19

1 Values for the population with the highest risk for each type of risk assessment are bolded. 

2 NA = Not Applicable; no acute dietary endpoint was identified for these population subgroups

VII. Characterization of Inputs/Outputs
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 8 of 17

The assumptions made in this assessment are conservative, and are very likely to result in 

exposure and risk values that considerably overestimate actual dietary exposure to 

flumioxazin. Although not needed at this time, the analyses could be further refined 

through the use of average residues based on field trial data, percent crop treated data 

and/or preparation/cooking factors. Since risk estimates are below HED’s level of 

concern, a more highly refined analysis is not needed at this time.

VIII.Conclusions

This highly conservative, unrefined analysis demonstrates that the requested uses for 

flumioxazin will not result in acute and chronic dietary risk estimates that exceed HED’s 

level of concern for any of the regulated populated subgroups, including those comprised 

of infants and children. 

IX. List of Attachments

Attachment 1: Acute Food plus Water Residue Input File

Attachment 2: Acute Results File

Attachment 3: Chronic Food plus Water Residue Input File

Attachment 4: Chronic Results File

.
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Attachment 1: Acute Food plus Water Residue Input File

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Acute analysis for FLUMIOXAZIN

Residue file name: C:\Deemfcid\FLUMIOXAZIN_ACUTE2.R08

Analysis Date 10-15-2012 Residue file dated: 10-15-2012/10:57:13

Reference dose: aRfD = 0.03 mg/kg bw/day NOEL = 3 mg/kg bw/day

Comment: Food + Drinking Water

----------------------------------------------------------------------------------

 EPA Crop Def Res Adj.Factors Comment

 Code Grp Food Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------ -------

1400003000 14 Almond 0.020000 1.000 1.000

1400003001 14 Almond-babyfood 0.020000 1.000 1.000

1400004000 14 Almond, oil 0.020000 1.000 1.000

1400004001 14 Almond, oil-babyfood 0.020000 1.000 1.000

1100007000 11 Apple, fruit with peel 0.020000 1.000 1.000

1100008000 11 Apple, peeled fruit 0.020000 1.000 1.000

1100008001 11 Apple, peeled fruit-babyfood 0.020000 1.000 1.000

1100009000 11 Apple, dried 0.020000 8.000 1.000

1100009001 11 Apple, dried-babyfood 0.020000 8.000 1.000

1100010000 11 Apple, juice 0.020000 1.300 1.000

1100010001 11 Apple, juice-babyfood 0.020000 1.300 1.000

1100011000 11 Apple, sauce 0.020000 1.000 1.000

1100011001 11 Apple, sauce-babyfood 0.020000 1.000 1.000

1202012000 12B Apricot 0.020000 1.000 1.000

1202012001 12B Apricot-babyfood 0.020000 1.000 1.000

1202013000 12B Apricot, dried 0.020000 6.000 1.000

1202014000 12B Apricot, juice 0.020000 1.000 1.000

1202014001 12B Apricot, juice-babyfood 0.020000 1.000 1.000

0103015000 1CD Arrowroot, flour 0.020000 1.000 1.000

0103015001 1CD Arrowroot, flour-babyfood 0.020000 1.000 1.000

9500016000 O Artichoke, globe 0.020000 1.000 1.000new us

 Full comment: new use

0103017000 1CD Artichoke, Jerusalem 0.020000 1.000 1.000

9500019000 O Asparagus 0.020000 1.000 1.000

0902021000 9B Balsam pear 0.030000 1.000 1.000

0603030000 6C Bean, black, seed 0.070000 1.000 1.000

0603032000 6C Bean, broad, seed 0.070000 1.000 1.000

0603034000 6C Bean, cowpea, seed 0.070000 1.000 1.000

0603035000 6C Bean, great northern, seed 0.070000 1.000 1.000

0603036000 6C Bean, kidney, seed 0.070000 1.000 1.000

0603038000 6C Bean, lima, seed 0.070000 1.000 1.000

0603039000 6C Bean, mung, seed 0.070000 1.000 1.000

0603040000 6C Bean, navy, seed 0.070000 1.000 1.000

0603041000 6C Bean, pink, seed 0.070000 1.000 1.000

0603042000 6C Bean, pinto, seed 0.070000 1.000 1.000

1302057000 13B Blueberry 0.020000 1.000 1.000

1302057001 13B Blueberry-babyfood 0.020000 1.000 1.000

1400059000 14 Brazil nut 0.020000 1.000 1.000

1400068000 14 Butternut 0.020000 1.000 1.000

0501069000 5A Cabbage 0.020000 1.000 1.000new us

 Full comment: new use

0502070000 5B Cabbage, Chinese, bok choy 0.020000 1.000 1.000new us

 Full comment: new use

0501071000 5A Cabbage, Chinese, napa 0.020000 1.000 1.000new us

 Full comment: new use

0501072000 5A Cabbage, Chinese, mustard 0.020000 1.000 1.000new us

 Full comment: new use

9500073000 O Cactus

 110-Uncooked; Fresh or N/S; Cook Meth N/S

 0.070000 1.000 1.000 new us

 Full comment: new use

 210-Cooked; Fresh or N/S; Cook Meth N/S

 0.070000 1.000 1.000 new us
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 10 of 17

 Full comment: new use

0901075000 9A Cantaloupe 0.030000 1.000 1.000

0402076000 4B Cardoon 0.020000 1.000 1.000

1400081000 14 Cashew 0.020000 1.000 1.000

0103082000 1CD Cassava 0.020000 1.000 1.000

0103082001 1CD Cassava-babyfood 0.020000 1.000 1.000

0402085000 4B Celery 0.020000 1.000 1.000

0402085001 4B Celery-babyfood 0.020000 1.000 1.000

0402086000 4B Celery, juice 0.020000 1.000 1.000

0402087000 4B Celtuce 0.020000 1.000 1.000

0902088000 9B Chayote, fruit 0.030000 1.000 1.000

1201090000 12A Cherry 0.020000 1.000 1.000

1201090001 12A Cherry-babyfood 0.020000 1.000 1.000

1201091000 12A Cherry, juice 0.020000 1.500 1.000

1201091001 12A Cherry, juice-babyfood 0.020000 1.500 1.000

1400092000 14 Chestnut 0.020000 1.000 1.000

0603098000 6C Chickpea, seed 0.070000 1.000 1.000

0603098001 6C Chickpea, seed-babyfood 0.070000 1.000 1.000

0603099000 6C Chickpea, flour 0.070000 1.000 1.000

0902102000 9B Chinese waxgourd 0.030000 1.000 1.000

1500120000 15 Corn, field, flour 0.020000 1.000 1.000

1500120001 15 Corn, field, flour-babyfood 0.020000 1.000 1.000

1500121000 15 Corn, field, meal 0.020000 1.000 1.000

1500121001 15 Corn, field, meal-babyfood 0.020000 1.000 1.000

1500122000 15 Corn, field, bran 0.020000 1.000 1.000

1500123000 15 Corn, field, starch 0.020000 1.000 1.000

1500123001 15 Corn, field, starch-babyfood 0.020000 1.000 1.000

1500124000 15 Corn, field, syrup 0.020000 1.000 1.000

1500124001 15 Corn, field, syrup-babyfood 0.020000 1.000 1.000

1500125000 15 Corn, field, oil 0.020000 1.000 1.000

1500125001 15 Corn, field, oil-babyfood 0.020000 1.000 1.000

2003128000 20C Cottonseed, oil 0.020000 1.000 1.000

2003128001 20C Cottonseed, oil-babyfood 0.020000 1.000 1.000

1100129000 11 Crabapple 0.020000 1.000 1.000

0902135000 9B Cucumber 0.030000 1.000 1.000

1302136000 13B Currant 0.020000 1.000 1.000

1302137000 13B Currant, dried 0.020000 1.000 1.000

0103139000 1CD Dasheen, corm 0.020000 1.000 1.000

0802148000 8BC Eggplant 0.020000 1.000 1.000

1302149000 13B Elderberry 0.020000 1.000 1.000

0402152000 4B Fennel, Florence 0.020000 1.000 1.000

1400155000 14 Hazelnut 0.020000 1.000 1.000

1400156000 14 Hazelnut, oil 0.020000 1.000 1.000

8000157000 80 Fish-freshwater finfish 1.500000 1.000 1.000

8000158000 80 Fish-freshwater finfish, farm ra 1.500000 1.000 1.000

2001163000 20A Flax seed, oil 0.400000 1.000 1.000

0301165000 3A Garlic, bulb 0.020000 1.000 1.000

0301165001 3A Garlic, bulb-babyfood 0.020000 1.000 1.000

0103166000 1CD Ginger 0.020000 1.000 1.000

0103166001 1CD Ginger-babyfood 0.020000 1.000 1.000

0103167000 1CD Ginger, dried 0.020000 1.000 1.000

1302174000 13B Gooseberry 0.020000 1.000 1.000

1304175000 13D Grape 0.020000 1.000 1.000

1304176000 13D Grape, juice 0.020000 1.200 1.000

1304176001 13D Grape, juice-babyfood 0.020000 1.200 1.000

9500177000 O Grape, leaves 0.020000 1.000 1.000

9500178000 O Grape, raisin 0.020000 4.300 1.000

1304179000 13D Grape, wine and sherry 0.020000 1.000 1.000

0603182000 6C Guar, seed 0.070000 1.000 1.000

0603182001 6C Guar, seed-babyfood 0.070000 1.000 1.000

1400185000 14 Hickory nut 0.020000 1.000 1.000

0901187000 9A Honeydew melon 0.030000 1.000 1.000

9500188000 O Hop 0.050000 1.000 1.000

1302191000 13B Huckleberry 0.020000 1.000 1.000

0603203000 6C Lentil, seed 0.070000 1.000 1.000

1100210000 11 Loquat 0.020000 1.000 1.000
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

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1400213000 14 Macadamia nut 0.020000 1.000 1.000

1202230000 12B Nectarine 0.020000 1.000 1.000

0802234000 8BC Okra 0.020000 1.000 1.000

9500235000 O Olive 0.020000 1.000 1.000new us

 Full comment: new use

9500236000 O Olive, oil 0.020000 1.000 1.000new us

 Full comment: new use

0301237000 3A Onion, bulb 0.020000 1.000 1.000

0301237001 3A Onion, bulb-babyfood 0.020000 1.000 1.000

0301238000 3A Onion, bulb, dried 0.020000 9.000 1.000

0301238001 3A Onion, bulb, dried-babyfood 0.020000 9.000 1.000

0603256000 6C Pea, dry 0.070000 1.000 1.000

0603256001 6C Pea, dry-babyfood 0.070000 1.000 1.000

0603258000 6C Pea, pigeon, seed 0.070000 1.000 1.000

1202260000 12B Peach 0.020000 1.000 1.000

1202260001 12B Peach-babyfood 0.020000 1.000 1.000

1202261000 12B Peach, dried 0.020000 7.000 1.000

1202261001 12B Peach, dried-babyfood 0.020000 7.000 1.000

1202262000 12B Peach, juice 0.020000 1.500 1.000

1202262001 12B Peach, juice-babyfood 0.020000 1.500 1.000

9500263000 O Peanut 0.020000 1.000 1.000

9500264000 O Peanut, butter 0.020000 1.890 1.000

9500265000 O Peanut, oil 0.020000 1.000 1.000

1100266000 11 Pear 0.020000 1.000 1.000

1100266001 11 Pear-babyfood 0.020000 1.000 1.000

1100267000 11 Pear, dried 0.020000 6.250 1.000

1100268000 11 Pear, juice 0.020000 1.500 1.000

1100268001 11 Pear, juice-babyfood 0.020000 1.000 1.000

1400269000 14 Pecan 0.020000 1.000 1.000

0802270000 8B Pepper, bell 0.020000 1.000 1.000

0802270001 8B Pepper, bell-babyfood 0.020000 1.000 1.000

0802271000 8B Pepper, bell, dried 0.020000 1.000 1.000

0802271001 8B Pepper, bell, dried-babyfood 0.020000 1.000 1.000

0802272000 8BC Pepper, nonbell 0.020000 1.000 1.000

0802272001 8BC Pepper, nonbell-babyfood 0.020000 1.000 1.000

0802273000 8BC Pepper, nonbell, dried 0.020000 1.000 1.000

9500275000 O Peppermint 0.040000 1.000 1.000

9500276000 O Peppermint, oil 0.040000 1.000 1.000

1400282000 14 Pistachio 0.020000 1.000 1.000

1203285000 12C Plum 0.020000 1.000 1.000

1203285001 12C Plum-babyfood 0.020000 1.000 1.000

1203286000 12C Plum, prune, fresh 0.020000 1.000 1.000

1203286001 12C Plum, prune, fresh-babyfood 0.020000 1.000 1.000

1203287000 12C Plum, prune, dried 0.020000 5.000 1.000

1203287001 12C Plum, prune, dried-babyfood 0.020000 5.000 1.000

1203288000 12C Plum, prune, juice 0.020000 1.400 1.000

1203288001 12C Plum, prune, juice-babyfood 0.020000 1.400 1.000

9500289000 O Pomegranate 0.020000 1.000 1.000new us

 Full comment: new use

0103296000 1C Potato, chips 0.020000 1.000 1.000

0103297000 1C Potato, dry (granules/ flakes) 0.020000 6.500 1.000

0103297001 1C Potato, dry (granules/ flakes)-b 0.020000 6.500 1.000

0103298000 1C Potato, flour 0.020000 1.000 1.000

0103298001 1C Potato, flour-babyfood 0.020000 1.000 1.000

0103299000 1C Potato, tuber, w/peel 0.020000 1.000 1.000

0103299001 1C Potato, tuber, w/peel-babyfood 0.020000 1.000 1.000

0103300000 1C Potato, tuber, w/o peel 0.020000 1.000 1.000

0103300001 1C Potato, tuber, w/o peel-babyfood 0.020000 1.000 1.000

0902308000 9B Pumpkin 0.030000 1.000 1.000

0902309000 9B Pumpkin, seed 0.030000 1.000 1.000

1100310000 11 Quince 0.020000 1.000 1.000

2001319000 20A Rapeseed, oil 0.400000 1.000 1.000

2001319001 20A Rapeseed, oil-babyfood 0.400000 1.000 1.000

0402322000 4B Rhubarb 0.020000 1.000 1.000

2002330000 20B Safflower, oil 0.500000 1.000 1.000

2002330001 20B Safflower, oil-babyfood 0.500000 1.000 1.000
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

______________________________________________________________________________________

Page 12 of 17

0600347000 6 Soybean, seed 0.020000 1.000 1.000

0603348000 6C Soybean, flour 0.020000 1.000 1.000

0603348001 6C Soybean, flour-babyfood 0.020000 1.000 1.000

0600349000 6 Soybean, soy milk 0.020000 1.000 1.000

0600349001 6 Soybean, soy milk-babyfood or in 0.020000 1.000 1.000

0600350000 6 Soybean, oil 0.020000 1.000 1.000

0600350001 6 Soybean, oil-babyfood 0.020000 1.000 1.000

9500352000 O Spearmint 0.040000 1.000 1.000

9500353000 O Spearmint, oil 0.040000 1.000 1.000

0902356000 9B Squash, summer 0.030000 1.000 1.000

0902356001 9B Squash, summer-babyfood 0.030000 1.000 1.000

0902357000 9B Squash, winter 0.030000 1.000 1.000

0902357001 9B Squash, winter-babyfood 0.030000 1.000 1.000

1307359000 13G Strawberry 0.070000 1.000 1.000

1307359001 13G Strawberry-babyfood 0.070000 1.000 1.000

1307360000 13G Strawberry, juice 0.070000 1.000 1.000

1307360001 13G Strawberry, juice-babyfood 0.070000 1.000 1.000

9500362000 O Sugarcane, sugar 0.200000 1.000 1.000

9500362001 O Sugarcane, sugar-babyfood 0.200000 1.000 1.000

9500363000 O Sugarcane, molasses 0.200000 1.000 1.000

9500363001 O Sugarcane, molasses-babyfood 0.200000 1.000 1.000

2002364000 20B Sunflower, seed 0.500000 1.000 1.000

2002365000 20B Sunflower, oil 0.500000 1.000 1.000

2002365001 20B Sunflower, oil-babyfood 0.500000 1.000 1.000

0103366000 1CD Sweet potato 0.020000 1.000 1.000

0103366001 1CD Sweet potato-babyfood 0.020000 1.000 1.000

0402367000 4B Swiss chard 0.020000 1.000 1.000

0103371000 1CD Tanier, corm 0.020000 1.000 1.000

0801374000 8A Tomatillo 0.020000 1.000 1.000

0801375000 8A Tomato 0.020000 1.000 1.000

0801375001 8A Tomato-babyfood 0.020000 1.000 1.000

0801376000 8A Tomato, paste 0.020000 1.000 1.000

0801376001 8A Tomato, paste-babyfood 0.020000 1.000 1.000

0801377000 8A Tomato, puree 0.020000 1.000 1.000

0801377001 8A Tomato, puree-babyfood 0.020000 1.000 1.000

0801378000 8A Tomato, dried 0.020000 1.000 1.000

0801378001 8A Tomato, dried-babyfood 0.020000 1.000 1.000

0801379000 8A Tomato, juice 0.020000 1.000 1.000

0103387000 1CD Turmeric 0.020000 1.000 1.000

1400391000 14 Walnut 0.020000 1.000 1.000

8601000000 86A Water, direct, all sources 0.400000 1.000 1.000aquati

 Full comment: aquatic herbicide 

8602000000 86B Water, indirect, all sources 0.400000 1.000 1.000aquati

 Full comment: aquatic herbicide 

0901399000 9A Watermelon 0.030000 1.000 1.000

0901400000 9A Watermelon, juice 0.030000 1.000 1.000

1500401000 15 Wheat, grain 0.400000 1.000 1.000

1500401001 15 Wheat, grain-babyfood 0.400000 1.000 1.000

1500402000 15 Wheat, flour 0.400000 1.000 1.000

1500402001 15 Wheat, flour-babyfood 0.400000 1.000 1.000

1500403000 15 Wheat, germ 0.400000 1.000 1.000

1500404000 15 Wheat, bran 0.400000 1.000 1.000

0103406000 1CD Yam, true 0.020000 1.000 1.000

0103407000 1CD Yam bean 0.020000 1.000 1.000

0301338000 3A Shallot, bulb 0.020000 1.000 1.000

1100173500 11 Goji berry 0.020000 1.000 1.000

Attachment 2: Acute Results File

US EPA Ver. 3.16, 03-08-d

DEEM-FCID ACUTE Analysis for FLUMIOXAZIN NHANES 2003-2008 2-Day

Residue file: FLUMIOXAZIN_ACUTE2.R08 Adjustment factor #2 NOT used.

Analysis Date: 10-15-2012/11:02:50 Residue file dated: 10-15-2012/10:57:13
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

______________________________________________________________________________________

Page 13 of 17

NOEL (Acute) = 3.000000 mg/kg body-wt/day

RAC/FF intake summed over 24 hours

Run Comment: "Food + Drinking Water"

===============================================================================

Summary calculations--per capita:

--- 95th Percentile---- --- 99th Percentile---- ---99.9th Percentile----

Exposure % aRfD MOE Exposure % aRfD MOE Exposure % aRfD MOE 

---------- ------- -------- ---------- ------- -------- ---------- ------- --------

Female 13-49:

 0.022607 75.36 132 0.033034 110.11 90 0.045900 153.00 65 

Attachment 3: Chronic Food plus Water Residue Input File

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for FLUMIOXAZIN

Residue file: C:\Deemfcid\FLUMIOXAZIN_CHRONIC2.R08 Adjust. #2 used

Analysis Date 08-31-2012 Residue file dated: 08-31-2012/17:39:04

Reference dose (RfD) = 0.02 mg/kg bw/day

Comment:Food + Drinking Water

----------------------------------------------------------------------------------

Food Crop Residue Adj.Factors

EPA Code Grp Food Name (ppm) #1 #2 

---------- ---- ------------------------------- ---------- ------ ------

1400003000 14 Almond 0.020000 1.000 1.000 

1400003001 14 Almond-babyfood 0.020000 1.000 1.000 

1400004000 14 Almond, oil 0.020000 1.000 1.000 

1400004001 14 Almond, oil-babyfood 0.020000 1.000 1.000 

1100007000 11 Apple, fruit with peel 0.020000 1.000 1.000 

1100008000 11 Apple, peeled fruit 0.020000 1.000 1.000 

1100008001 11 Apple, peeled fruit-babyfood 0.020000 1.000 1.000 

1100009000 11 Apple, dried 0.020000 8.000 1.000 

1100009001 11 Apple, dried-babyfood 0.020000 8.000 1.000 

1100010000 11 Apple, juice 0.020000 1.300 1.000 

1100010001 11 Apple, juice-babyfood 0.020000 1.300 1.000 

1100011000 11 Apple, sauce 0.020000 1.000 1.000 

1100011001 11 Apple, sauce-babyfood 0.020000 1.000 1.000 

1202012000 12B Apricot 0.020000 1.000 1.000 

1202012001 12B Apricot-babyfood 0.020000 1.000 1.000 

1202013000 12B Apricot, dried 0.020000 6.000 1.000 

1202014000 12B Apricot, juice 0.020000 1.000 1.000 

1202014001 12B Apricot, juice-babyfood 0.020000 1.000 1.000 

0103015000 1CD Arrowroot, flour 0.020000 1.000 1.000 

0103015001 1CD Arrowroot, flour-babyfood 0.020000 1.000 1.000 

9500016000 O Artichoke, globe 0.060000 1.000 1.000 

0103017000 1CD Artichoke, Jerusalem 0.020000 1.000 1.000 

9500019000 O Asparagus 0.020000 1.000 1.000 

0902021000 9B Balsam pear 0.030000 1.000 1.000 

0603030000 6C Bean, black, seed 0.070000 1.000 1.000 

0603032000 6C Bean, broad, seed 0.070000 1.000 1.000 

0603034000 6C Bean, cowpea, seed 0.070000 1.000 1.000 

0603035000 6C Bean, great northern, seed 0.070000 1.000 1.000 

0603036000 6C Bean, kidney, seed 0.070000 1.000 1.000 

0603038000 6C Bean, lima, seed 0.070000 1.000 1.000 

0603039000 6C Bean, mung, seed 0.070000 1.000 1.000 

0603040000 6C Bean, navy, seed 0.070000 1.000 1.000 

0603041000 6C Bean, pink, seed 0.070000 1.000 1.000 

0603042000 6C Bean, pinto, seed 0.070000 1.000 1.000 

1302057000 13B Blueberry 0.020000 1.000 1.000 

1302057001 13B Blueberry-babyfood 0.020000 1.000 1.000 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

______________________________________________________________________________________

Page 14 of 17

1400059000 14 Brazil nut 0.020000 1.000 1.000 

1400068000 14 Butternut 0.020000 1.000 1.000 

0501069000 5A Cabbage 0.060000 1.000 1.000 

0502070000 5B Cabbage, Chinese, bok choy 0.060000 1.000 1.000 

0501071000 5A Cabbage, Chinese, napa 0.060000 1.000 1.000 

0501072000 5A Cabbage, Chinese, mustard 0.060000 1.000 1.000 

9500073000 O Cactus 0.070000 1.000 1.000 

0901075000 9A Cantaloupe 0.030000 1.000 1.000 

0402076000 4B Cardoon 0.020000 1.000 1.000 

1400081000 14 Cashew 0.020000 1.000 1.000 

0103082000 1CD Cassava 0.020000 1.000 1.000 

0103082001 1CD Cassava-babyfood 0.020000 1.000 1.000 

0402085000 4B Celery 0.020000 1.000 1.000 

0402085001 4B Celery-babyfood 0.020000 1.000 1.000 

0402086000 4B Celery, juice 0.020000 1.000 1.000 

0402087000 4B Celtuce 0.020000 1.000 1.000 

0902088000 9B Chayote, fruit 0.030000 1.000 1.000 

1201090000 12A Cherry 0.020000 1.000 1.000 

1201090001 12A Cherry-babyfood 0.020000 1.000 1.000 

1201091000 12A Cherry, juice 0.020000 1.500 1.000 

1201091001 12A Cherry, juice-babyfood 0.020000 1.500 1.000 

1400092000 14 Chestnut 0.020000 1.000 1.000 

0603098000 6C Chickpea, seed 0.070000 1.000 1.000 

0603098001 6C Chickpea, seed-babyfood 0.070000 1.000 1.000 

0603099000 6C Chickpea, flour 0.070000 1.000 1.000 

0902102000 9B Chinese waxgourd 0.030000 1.000 1.000 

1500120000 15 Corn, field, flour 0.020000 1.000 1.000 

1500120001 15 Corn, field, flour-babyfood 0.020000 1.000 1.000 

1500121000 15 Corn, field, meal 0.020000 1.000 1.000 

1500121001 15 Corn, field, meal-babyfood 0.020000 1.000 1.000 

1500122000 15 Corn, field, bran 0.020000 1.000 1.000 

1500123000 15 Corn, field, starch 0.020000 1.000 1.000 

1500123001 15 Corn, field, starch-babyfood 0.020000 1.000 1.000 

1500124000 15 Corn, field, syrup 0.020000 1.000 1.000 

1500124001 15 Corn, field, syrup-babyfood 0.020000 1.000 1.000 

1500125000 15 Corn, field, oil 0.020000 1.000 1.000 

1500125001 15 Corn, field, oil-babyfood 0.020000 1.000 1.000 

2003128000 20C Cottonseed, oil 0.020000 1.000 1.000 

2003128001 20C Cottonseed, oil-babyfood 0.020000 1.000 1.000 

1100129000 11 Crabapple 0.020000 1.000 1.000 

0902135000 9B Cucumber 0.030000 1.000 1.000 

1302136000 13B Currant 0.020000 1.000 1.000 

1302137000 13B Currant, dried 0.020000 1.000 1.000 

0103139000 1CD Dasheen, corm 0.020000 1.000 1.000 

0802148000 8BC Eggplant 0.020000 1.000 1.000 

1302149000 13B Elderberry 0.020000 1.000 1.000 

0402152000 4B Fennel, Florence 0.020000 1.000 1.000 

1400155000 14 Hazelnut 0.020000 1.000 1.000 

1400156000 14 Hazelnut, oil 0.020000 1.000 1.000 

8000157000 80 Fish-freshwater finfish 1.500000 1.000 1.000 

8000158000 80 Fish-freshwater finfish, farm ra 1.500000 1.000 1.000 

2001163000 20A Flax seed, oil 0.400000 1.000 1.000 

0301165000 3A Garlic, bulb 0.020000 1.000 1.000 

0301165001 3A Garlic, bulb-babyfood 0.020000 1.000 1.000 

0103166000 1CD Ginger 0.020000 1.000 1.000 

0103166001 1CD Ginger-babyfood 0.020000 1.000 1.000 

0103167000 1CD Ginger, dried 0.020000 1.000 1.000 

1302174000 13B Gooseberry 0.020000 1.000 1.000 

1304175000 13D Grape 0.020000 1.000 1.000 

1304176000 13D Grape, juice 0.020000 1.200 1.000 

1304176001 13D Grape, juice-babyfood 0.020000 1.200 1.000 

9500177000 O Grape, leaves 0.020000 1.000 1.000 

9500178000 O Grape, raisin 0.020000 4.300 1.000 

1304179000 13D Grape, wine and sherry 0.020000 1.000 1.000 

0603182000 6C Guar, seed 0.070000 1.000 1.000 

0603182001 6C Guar, seed-babyfood 0.070000 1.000 1.000 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

______________________________________________________________________________________

Page 15 of 17

1400185000 14 Hickory nut 0.020000 1.000 1.000 

0901187000 9A Honeydew melon 0.030000 1.000 1.000 

9500188000 O Hop 0.050000 1.000 1.000 

1302191000 13B Huckleberry 0.020000 1.000 1.000 

0603203000 6C Lentil, seed 0.070000 1.000 1.000 

1100210000 11 Loquat 0.020000 1.000 1.000 

1400213000 14 Macadamia nut 0.020000 1.000 1.000 

1202230000 12B Nectarine 0.020000 1.000 1.000 

0802234000 8BC Okra 0.020000 1.000 1.000 

9500235000 O Olive 0.060000 1.000 1.000 

9500236000 O Olive, oil 0.060000 1.000 1.000 

0301237000 3A Onion, bulb 0.020000 1.000 1.000 

0301237001 3A Onion, bulb-babyfood 0.020000 1.000 1.000 

0301238000 3A Onion, bulb, dried 0.020000 9.000 1.000 

0301238001 3A Onion, bulb, dried-babyfood 0.020000 9.000 1.000 

0603256000 6C Pea, dry 0.070000 1.000 1.000 

0603256001 6C Pea, dry-babyfood 0.070000 1.000 1.000 

0603258000 6C Pea, pigeon, seed 0.070000 1.000 1.000 

1202260000 12B Peach 0.020000 1.000 1.000 

1202260001 12B Peach-babyfood 0.020000 1.000 1.000 

1202261000 12B Peach, dried 0.020000 7.000 1.000 

1202261001 12B Peach, dried-babyfood 0.020000 7.000 1.000 

1202262000 12B Peach, juice 0.020000 1.500 1.000 

1202262001 12B Peach, juice-babyfood 0.020000 1.500 1.000 

9500263000 O Peanut 0.020000 1.000 1.000 

9500264000 O Peanut, butter 0.020000 1.890 1.000 

9500265000 O Peanut, oil 0.020000 1.000 1.000 

1100266000 11 Pear 0.020000 1.000 1.000 

1100266001 11 Pear-babyfood 0.020000 1.000 1.000 

1100267000 11 Pear, dried 0.020000 6.250 1.000 

1100268000 11 Pear, juice 0.020000 1.000 1.000 

1100268001 11 Pear, juice-babyfood 0.020000 1.000 1.000 

1400269000 14 Pecan 0.020000 1.000 1.000 

0802270000 8B Pepper, bell 0.020000 1.000 1.000 

0802270001 8B Pepper, bell-babyfood 0.020000 1.000 1.000 

0802271000 8B Pepper, bell, dried 0.020000 1.000 1.000 

0802271001 8B Pepper, bell, dried-babyfood 0.020000 1.000 1.000 

0802272000 8BC Pepper, nonbell 0.020000 1.000 1.000 

0802272001 8BC Pepper, nonbell-babyfood 0.020000 1.000 1.000 

0802273000 8BC Pepper, nonbell, dried 0.020000 1.000 1.000 

9500275000 O Peppermint 0.040000 1.000 1.000 

9500276000 O Peppermint, oil 0.040000 1.000 1.000 

1400282000 14 Pistachio 0.020000 1.000 1.000 

1203285000 12C Plum 0.020000 1.000 1.000 

1203285001 12C Plum-babyfood 0.020000 1.000 1.000 

1203286000 12C Plum, prune, fresh 0.020000 1.000 1.000 

1203286001 12C Plum, prune, fresh-babyfood 0.020000 1.000 1.000 

1203287000 12C Plum, prune, dried 0.020000 5.000 1.000 

1203287001 12C Plum, prune, dried-babyfood 0.020000 5.000 1.000 

1203288000 12C Plum, prune, juice 0.020000 1.400 1.000 

1203288001 12C Plum, prune, juice-babyfood 0.020000 1.400 1.000 

9500289000 O Pomegranate 0.060000 1.000 1.000 

0103296000 1C Potato, chips 0.020000 1.000 1.000 

0103297000 1C Potato, dry (granules/ flakes) 0.020000 6.500 1.000 

0103297001 1C Potato, dry (granules/ flakes)-b 0.020000 6.500 1.000 

0103298000 1C Potato, flour 0.020000 1.000 1.000 

0103298001 1C Potato, flour-babyfood 0.020000 1.000 1.000 

0103299000 1C Potato, tuber, w/peel 0.020000 1.000 1.000 

0103299001 1C Potato, tuber, w/peel-babyfood 0.020000 1.000 1.000 

0103300000 1C Potato, tuber, w/o peel 0.020000 1.000 1.000 

0103300001 1C Potato, tuber, w/o peel-babyfood 0.020000 1.000 1.000 

0902308000 9B Pumpkin 0.030000 1.000 1.000 

0902309000 9B Pumpkin, seed 0.030000 1.000 1.000 

1100310000 11 Quince 0.020000 1.000 1.000 

2001319000 20A Rapeseed, oil 0.400000 1.000 1.000 

2001319001 20A Rapeseed, oil-babyfood 0.400000 1.000 1.000 
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

______________________________________________________________________________________

Page 16 of 17

0402322000 4B Rhubarb 0.020000 1.000 1.000 

2002330000 20B Safflower, oil 0.500000 1.000 1.000 

2002330001 20B Safflower, oil-babyfood 0.500000 1.000 1.000 

0600347000 6 Soybean, seed 0.020000 1.000 1.000 

0603348000 6C Soybean, flour 0.020000 1.000 1.000 

0603348001 6C Soybean, flour-babyfood 0.020000 1.000 1.000 

0600349000 6 Soybean, soy milk 0.020000 1.000 1.000 

0600349001 6 Soybean, soy milk-babyfood or in 0.020000 1.000 1.000 

0600350000 6 Soybean, oil 0.020000 1.000 1.000 

0600350001 6 Soybean, oil-babyfood 0.020000 1.000 1.000 

9500352000 O Spearmint 0.040000 1.000 1.000 

9500353000 O Spearmint, oil 0.040000 1.000 1.000 

0902356000 9B Squash, summer 0.030000 1.000 1.000 

0902356001 9B Squash, summer-babyfood 0.030000 1.000 1.000 

0902357000 9B Squash, winter 0.030000 1.000 1.000 

0902357001 9B Squash, winter-babyfood 0.030000 1.000 1.000 

1307359000 13G Strawberry 0.070000 1.000 1.000 

1307359001 13G Strawberry-babyfood 0.070000 1.000 1.000 

1307360000 13G Strawberry, juice 0.070000 1.000 1.000 

1307360001 13G Strawberry, juice-babyfood 0.070000 1.000 1.000 

9500362000 O Sugarcane, sugar 0.200000 1.000 1.000 

9500362001 O Sugarcane, sugar-babyfood 0.200000 1.000 1.000 

9500363000 O Sugarcane, molasses 0.200000 1.000 1.000 

9500363001 O Sugarcane, molasses-babyfood 0.200000 1.000 1.000 

2002364000 20B Sunflower, seed 0.500000 1.000 1.000 

2002365000 20B Sunflower, oil 0.500000 1.000 1.000 

2002365001 20B Sunflower, oil-babyfood 0.500000 1.000 1.000 

0103366000 1CD Sweet potato 0.020000 1.000 1.000 

0103366001 1CD Sweet potato-babyfood 0.020000 1.000 1.000 

0402367000 4B Swiss chard 0.020000 1.000 1.000 

0103371000 1CD Tanier, corm 0.020000 1.000 1.000 

0801374000 8A Tomatillo 0.020000 1.000 1.000 

0801375000 8A Tomato 0.020000 1.000 1.000 

0801375001 8A Tomato-babyfood 0.020000 1.000 1.000 

0801376000 8A Tomato, paste 0.020000 1.000 1.000 

0801376001 8A Tomato, paste-babyfood 0.020000 1.000 1.000 

0801377000 8A Tomato, puree 0.020000 1.000 1.000 

0801377001 8A Tomato, puree-babyfood 0.020000 1.000 1.000 

0801378000 8A Tomato, dried 0.020000 1.000 1.000 

0801378001 8A Tomato, dried-babyfood 0.020000 1.000 1.000 

0801379000 8A Tomato, juice 0.020000 1.000 1.000 

0103387000 1CD Turmeric 0.020000 1.000 1.000 

1400391000 14 Walnut 0.020000 1.000 1.000 

8601000000 86A Water, direct, all sources 0.142000 1.000 1.000 

8602000000 86B Water, indirect, all sources 0.142000 1.000 1.000 

0901399000 9A Watermelon 0.030000 1.000 1.000 

0901400000 9A Watermelon, juice 0.030000 1.000 1.000 

1500401000 15 Wheat, grain 0.400000 1.000 1.000 

1500401001 15 Wheat, grain-babyfood 0.400000 1.000 1.000 

1500402000 15 Wheat, flour 0.400000 1.000 1.000 

1500402001 15 Wheat, flour-babyfood 0.400000 1.000 1.000 

1500403000 15 Wheat, germ 0.400000 1.000 1.000 

1500404000 15 Wheat, bran 0.400000 1.000 1.000 

0103406000 1CD Yam, true 0.020000 1.000 1.000 

0103407000 1CD Yam bean 0.020000 1.000 1.000 

0301338000 3A Shallot, bulb 0.020000 1.000 1.000 

1100173500 11 Goji berry 0.020000 1.000 1.000 

Attachment 4: Chronic Results File
Flumioxazin Dietary Exposure and Risk Assessment DP Number: 406069

PC Code: 129034

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Page 17 of 17

US EPA Ver. 3.16, 03-08-d

DEEM-FCID Chronic analysis for FLUMIOXAZIN NHANES 2003-2008 2-day

Residue file name: C:\Deemfcid\FLUMIOXAZIN_CHRONIC.R08

 Adjustment factor #2 NOT used.

Analysis Date 10-15-2012/11:22:21 Residue file dated: 10-15-2012/11:19:15

Reference dose (RfD, Chronic) = .02 mg/kg bw/day

COMMENT 1: Food + Drinking Water

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 Total exposure by population subgroup

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 Total Exposure

 -----------------------------------

 Population mg/kg Percent of 

 Subgroup body wt/day Rfd 

-------------------------------------- ------------- ----------------

Total US Population 0.003932 19.7%

Hispanic 0.003804 19.0%

Non-Hisp-White 0.004018 20.1%

Non-Hisp-Black 0.003371 16.9%

Non-Hisp-Other 0.004465 22.3%

Nursing Infants 0.003246 16.2%

Non-Nursing Infants 0.011213 56.1%

Female 13+ PREG 0.003582 17.9%

Children 1-6 0.006199 31.0%

Children 7-12 0.004024 20.1%

Male 13-19 0.003069 15.3%

Female 13-19/NP 0.003164 15.8%

Male 20+ 0.003539 17.7%

Female 20+/NP 0.003812 19.1%

Seniors 55+ 0.003567 17.8%

All Infants 0.008753 43.8%

Female 13-50 0.003692 18.5%

Children 1-2 0.006811 34.1%

Children 3-5 0.005959 29.8%

Children 6-12 0.004253 21.3%

Youth 13-19 0.003116 15.6%

Adults 20-49 0.003715 18.6%

Adults 50-99 0.003633 18.2%

Female 13-49 0.003692 18.5%

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