Federal Register / Vol. 76, No. 38 / Friday, February 25, 2011 / Notices 10591 

accommodate this need and allow 

registrants time to develop replacement 

products. The current temephos 

products would not be cancelled until 

December 30, 2015. For these reasons, 

the Agency does not believe that the 

comment period should be extended. 

IV. Cancellation Order 

Pursuant to FIFRA section 6(f), EPA 

hereby approves the requested 

cancellations of the registrations 

identified in Tables 1, 2, and 3 of Unit 

II. Accordingly, the Agency hereby 

orders that the product registrations 

identified in Tables 1, 2, and 3 of Unit 

II. are cancelled. The effective date of 

the cancellation of the products listed in 

Tables 1 and 3 of this notice is February 

25, 2011. The effective date of the 

cancellation of the products listed in 

Table 2 is December 31, 2015. Any 

distribution, sale, or use of existing 

stocks of the products identified in 

Tables 1, 2, and 3 of Unit II. in a manner 

inconsistent with any of the provisions 

for disposition of existing stocks set 

forth in Unit VI. will be a violation of 

FIFRA. 

V. What is the agency’s authority for 

taking this action? 

Section 6(f)(1) of FIFRA provides that 

a registrant of a pesticide product may 

at any time request that any of its 

pesticide registrations be canceled or 

amended to terminate one or more uses. 

FIFRA further provides that, before 

acting on the request, EPA must publish 

a notice of receipt of any such request 

in the Federal Register. Thereafter, 

following the public comment period, 

the EPA Administrator may approve 

such a request. The notices of receipt for 

this action were published for comment 

in the Federal Register issues of 

November 10, 2010 (75 FR 69073) (FRL– 

8851–5) and November 17, 2010 (75 FR 

70256) (FRL–8850–1). The comment 

periods closed on December 10, 2010 

and December 17, 2010 respectively. 

VI. Provisions for Disposition of 

Existing Stocks 

Existing stocks are those stocks of 

registered pesticide products which are 

currently in the United States and 

which were packaged, labeled, and 

released for shipment prior to the 

effective date of the cancellation action. 

The existing stocks provisions for the 

products subject to this order are as 

follows. 

A. For All Products Listed in Table 1 of 

Unit II 

The registrants may continue to sell 

and distribute existing stocks of 

products listed in Table 1 of Unit II. 

until February 25, 2012, which is 1 year 

after the publication of the Cancellation 

Order in the Federal Register. 

Thereafter, the registrants are prohibited 

from selling or distributing products 

listed in Table 1, except for export in 

accordance with FIFRA section 17, or 

proper disposal. Persons other than the 

registrants may sell, distribute, or use 

existing stocks of products listed in 

Table 1 of Unit II. until existing stocks 

are exhausted, provided that such sale, 

distribution, or use is consistent with 

the terms of the previously approved 

labeling on, or that accompanied, the 

canceled products. 

B. For All Products Listed in Table 2 of 

Unit II 

After December 31, 2015, registrants 

are prohibited from selling or 

distributing existing stocks of products 

containing temephos labeled for all 

uses. 

After December 31, 2016, persons 

other than registrants are prohibited 

from selling or distributing existing 

stocks of products containing temephos 

labeled for all uses. 

After December 31, 2016, existing 

stocks of products containing temephos 

labeled for all uses, already in the hands 

of users can be used legally until they 

are exhausted, provided that such use 

complies with the EPA-approved label 

and labeling of the affected product. 

C. For All Products Listed in Table 3 of 

Unit II 

All sale or distribution by the 

registrant of existing stocks is prohibited 

after publication of the cancellation 

order in the Federal Register, unless 

that sale or distribution is solely for the 

purpose of facilitating disposal or export 

of the product. 

Existing stocks may be sold and 

distributed by persons other than the 

registrant for 120 days from the effective 

date of the cancellation order. 

Existing stocks may be used until 

exhausted, provided that such use 

complies with the EPA-approved label 

and labeling of the product. 

List of Subjects 

Environmental protection, Pesticides 

and pests. 

Dated: February 8, 2011. 

Richard P. Keigwin, Jr., 

Director, Pesticide Re-evaluation Division, 

Office of Pesticide Programs. 

[FR Doc. 2011–4140 Filed 2–24–11; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA/100/R–11/001; FRL–9270–7] 

Notice of Availability; Recommended 

Use of Body Weight3⁄

4 as the Default 

Method in Derivation of the Oral 

Reference Dose 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice of availability. 

SUMMARY: This notice announces the 

availability of ‘‘Recommended Use of 

Body Weight3/4 as the Default Method in 

Derivation of the Oral Reference Dose’’ 

(referred to hereafter as BW3/4). This 

document was developed as part of an 

Agency-wide guidance development 

program by a technical panel of the U.S. 

EPA’s Risk Assessment Forum, 

composed of scientists from across the 

Agency. Selected drafts were peer 

reviewed internally by EPA scientists 

and externally by experts from 

academia, industry, environmental 

groups and other government agencies. 

DATES: The document will be available 

for use by EPA risk assessors on 

February 25, 2011. 

ADDRESSES: The Guidelines are 

available electronically through the EPA 

Web site at http://www.epa.gov/raf/

publications/interspeciesextrapolation.htm. A limited number of 

paper copies will be available from 

EPA’s National Service Center for 

Environmental Publications (NSCEP), 

P.O. Box 42419, Cincinnati, OH 45242; 

telephone (800) 490–9198 or (513) 489– 

8695; facsimile: (513) 489–8190. Please 

provide your name, mailing address and 

the title and number of the requested 

publication. Additionally, copies of the 

document will be available for 

inspection at EPA headquarters and 

regional libraries, through the U.S. 

Government Depository Library 

program. 

FOR FURTHER INFORMATION CONTACT: Dr. 

Michael W. Broder, Risk Assessment 

Forum, Office of the Science Advisor 

(8105R), U.S. Environmental Protection 

Agency, Washington, DC 20460; 

telephone (202) 564–3393 or e-mail: 

broder.michael@epa.gov. 

SUPPLEMENTARY INFORMATION: In order to 

assess the toxicity of a particular 

chemical in the absence of human data, 

EPA relies on the use of animal models 

as surrogates. EPA endorses a hierarchy 

of approaches to derive human 

equivalent oral exposures from data 

from laboratory animal species, with the 

preferred approach being 

physiologically based toxicokinetic 


srobinson on DSKHWCL6B1PROD with NOTICES
10592 Federal Register / Vol. 76, No. 38 / Friday, February 25, 2011 / Notices 

modeling. As a default method to 

account for differences in dosimetry 

between the animal models and 

humans, EPA previously applied a 

direct body-weight conversion from the 

model to humans (i.e., BW1/1) for noncancer endpoints, in the absence of 

chemical-specific data. In contrast, EPA 

applies a dosimetric adjustment factor 

(DAF) based on body weight raised to 

the three-quarter power (BW3/4) for 

cancer assessments. By adopting the 

adjustment, this document moves in the 

direction of harmonizing the approach 

for assessing cancer and noncancer 

endpoints. 

In addition to laying out the 

computational method for interspecies 

extrapolation, the document also 

addresses the issue of changes to the 

interspecies uncertainty factor (UFA). 

The document recommends a reduced 

interspecies UFA (with a default value of 

3) in lieu of a default of 10 for the 

reference dose (RfD) calculation. The 

quantitative significance of this 

procedure with regard to the magnitude 

of an RfD will depend on the body 

weight of the species (as well as the 

value assigned to the UFA) and may be 

more or less than the current procedure 

of dividing by the default composite 

UFA of 10. 

BW3/4 scaling for derivation of the 

human equivalent dose is recommended 

as the default approach for RfDs for 

remote, as well as portal-of-entry effects. 

It is noted that this scaling is not 

inclusive of lethal or frank effects for 

which maximum concentration (Cmax) 

may be the most appropriate dose 

metric and that such effects are not 

among those effects recommended for 

use in deriving RfDs (USEPA, 2002). 

This default approach generally applies 

to different durations of exposure. The 

reader is encouraged to read the 

document carefully, however, in order 

to fully understand how to apply the 

policy appropriately. Additionally, 

although non-oral RfDs can be estimated 

(e.g., a dermal RfD), this document 

focuses only on oral RfDs and for this 

document the acronym refers only to 

RfDs for oral exposure. 

It is recognized that this procedure, as 

with all default procedures, may not 

always predict oral exposures associated 

with precise toxicologically-equivalent 

doses for specific chemicals. It should 

be emphasized that other biological 

information not discussed in this 

document may inform interspecies 

adjustments. As a general default 

procedure, however, it may be 

anticipated to provide a reasonable 

description of average behavior of many 

chemicals much of the time. 

Even though this document is not a 

binding rule, EPA is issuing it in a 

manner consistent with the procedures 

in the Administrative Procedure Act 

that are generally applicable to 

rulemaking, including providing 

opportunity for public comment. EPA 

considered and responded to all 

significant public comments as it 

prepared the document. 

Dated: February 16, 2011. 

Paul T. Anastas, 

EPA Science Advisor. 

[FR Doc. 2011–4250 Filed 2–24–11; 8:45 am] 

BILLING CODE 6560–50–P 

FEDERAL COMMUNICATIONS 

COMMISSION 

Notice of Public Information 

Collection(s) Being Reviewed by the 

Federal Communications Commission, 

Comments Requested 

February 18, 2011. 

SUMMARY: The Federal Communications 

Commission, as part of its continuing 

effort to reduce paperwork burden 

invites the general public and other 

Federal agencies to take this 

opportunity to comment on the 

following information collection(s), as 

required by the Paperwork Reduction 

Act (PRA) of 1995, 44 U.S.C. 3501— 

3520. Comments are requested 

concerning: (a) Whether the proposed 

collection of information is necessary 

for the proper performance of the 

functions of the Commission, including 

whether the information shall have 

practical utility; (b) the accuracy of the 

Commission’s burden estimate; (c) ways 

to enhance the quality, utility, and 

clarity of the information collected; (d) 

ways to minimize the burden of the 

collection of information on the 

respondents, including the use of 

automated collection techniques or 

other forms of information technology, 

and (e) ways to further reduce the 

information collection burden on small 

business concerns with fewer than 25 

employees. 

The FCC may not conduct or sponsor 

a collection of information unless it 

displays a currently valid OMB control 

number. No person shall be subject to 

any penalty for failing to comply with 

a collection of information subject to the 

Paperwork Reduction Act (PRA) that 

does not display a currently valid OMB 

control number. 

DATES: Written Paperwork Reduction 

Act (PRA) comments should be 

submitted on or before April 26, 2011. 

If you anticipate that you will be 

submitting PRA comments, but find it 

difficult to do so within the period of 

time allowed by this notice, you should 

advise the FCC contact listed below as 

soon as possible. 

ADDRESSES: Direct all PRA comments to 

the Federal Communications 

Commission via e-mail to PRA@fcc.gov. 

FOR FURTHER INFORMATION CONTACT: 

Judith B. Herman, Office of Managing 

Director, (202) 418–0214. For additional 

information, contact Judith B. Herman, 

OMD, 202–418–0214 or e-mail judithb.herman@fcc.gov. 

SUPPLEMENTARY INFORMATION: 

OMB Control Number: 3060–1113. 

Title: Commercial Mobile Alert 

System (CMAS). 

Form No.: N/A. 

Type of Review: Revision of a 

currently approved collection. 

Respondents: Business or other forprofit. 

Number of Respondents and 

Responses: 1,253 respondents; 1,253 

responses. 

Estimated Time per Response: .5 

hours. 

Frequency of Response: On occasion 

reporting requirement, recordkeeping 

requirement and third party disclosure 

requirement. 

Obligation to Respond: Mandatory. 

Statutory authority for this information 

collection is contained in 47 U.S.C. 151, 

154(i), 154(j), 154(o), 218, 219, 230, 256, 

301, 302(a), 303(f), 303(g), 303(j), 303(r), 

403, 621(b)(3), and 621(d). 

Total Annual Burden: 627 hours. 

Total Annual Cost: N/A. 

Privacy Act Impact Assessment: N/A. 

Nature and Extent of Confidentiality: 

There is no need for confidentiality. 

Needs and Uses: The Commission 

will submit this expiring information 

collection after this comment period to 

the Office of Management and Budget 

(OMB) to obtain the three year clearance 

from them. The Commission is reporting 

a 502 hour increase in the total annual 

burden. The Commission will submit 

this collection to the OMB as a revision. 

This information collection is being 

submitted because, in the Third Report 

and Order in PS Docket No. 07–287, 

FCC 08–184, the Commission adopted 

rules that require Commercial Mobile 

Service (CMS) providers to collect 

information subject to the Paperwork 

Reduction Act. In the Third Report and 

Order, the Commission adopted rules 

obligating entities participating in the 

Commercial Mobile Alert System 

(CMAS) to provide written election of 

intent to participate in the CMAS. 

All CMS providers are required to 

submit a CMAS election, including 

those that were not licensed at the time 

of the initial deadline for filing an 


srobinson on DSKHWCL6B1PROD with NOTICES