This List of Cosm Endpoints is the same list provided in appendix D of the white paper. The data 

Initial 

Test 

Conc 

(μg/L)

Duration (d)* Effect (Y/N)? Reference(s)

0.5 7 N Brockway et al. 1984

0.5 29 N Brockway et al. 1984

1 20 N Gustavson and Wängberg 1995

5 7 N Brockway et al. 1984

2 28 N Jurgensen and Hoagland 1990

3.2 21 N Pratt et al. 1988

5 14 N Gruessner and Watzin 1996

5 35 N van den Brink et al. 1995

10 20 N Gustavson and Wängberg 1995

10 21 N Pratt et al. 1988

10 30 N Johnson 1986

5 70 N Brockway et al. 1984

20 20 N Gustavson and Wängberg 1995

25 30 N Lynch et al. 1985

20 42 N Stay et al. 1989

30 28 N Jurgensen and Hoagland 1990

100 28 N Jurgensen and Hoagland 1990

100 30 N Johnson 1986

6.4 36 N Relyea, 2009

30 40 N Seguin et al. 2001a

2 40 N Seguin et al. 2001a

Original Data

207 25 N Boone and James (2003)

20 51 N Diana et al. (2000)

25 42 N McGregor et al. (2008)

50 42 N McGregor et al. (2008)

2 40 Y Seguin et al. 2001b

1078 0.083333333 Y Guasch and Sabater (1998)

10 10 Y

Berard et al. 1999a1, Berard et al. 

1999b, Berard and Benninghoff 

2001, Sequin et al. 2001b, 

Leboulanger et al. 2001

24.3 7 Y Downing et al. 2004

10 21 Y

Kosinski 1984; Kosinski and 

Merkle 1984

15 15 Y Detenback et al 1996

24 12 Y Krieger et al. 1988

50 12 Y Brockway et al. 1984

32 21 Y Pratt et al. 1988

100 7 Y Brockway et al. 1984

100 7 Y Moorhead and Kosinski 1986

25 30 Y Rohr and Crumrine, 2005

30 25 Y Seguin et al. 2002

148 7 Y Downing et al. 2004
25 43

Y Detenback et al 1996

30 40Y Seguin et al. 2001b

20 63Y

deNoyelles et al. 1982; deNoyelles 

et al. 1989

79 17Y Detenback et al 1996

100 14Y Hamala and Kollig 1985

100 15Y Brockway et al. 1984

50 32Y Detenback et al 1996

134 12Y Krieger et al. 1988

20 365Y

Carney 1983; Kettle et al. 1987; 

deNoyelles et al. 1989; deNoyelles 

et al. 1994, deNoyelles & Kettle 

1980, Dewey 1986

100 21Y

Kosinski 1984; Kosinski and 

Merkle 1984

110 21Y Pratt et al. 1988

50 55Y Brockway et al. 1984

53 53Y Stay et al. 1985

117 28Y Rohr et al., 2008

100 42Y Stay et al. 1989

100 42Y McGregor et al. (2008)

84 53Y Stay et al. 1985

80 56Y Hamilton et al 1987

500 12Y Brockway et al. 1984

10007Y Moorhead and Kosinski 1986

337 21Y Pratt et al. 1988

140 56Y Hamilton et al 1987

204 42Y Stay et al. 1989

100 365Y

deNoyelles et al. 1989 Carney 100 365 YdeNoyelles et al. 1989 Carney

1983

100 96Y Hamilton et al. 1988

100 96Y

Herman et al. 1986; Hamilton et al. 

1989

100 360Y deNoyelles et al. 1989

170 53Y Stay et al. 1985

196 51Y Diana et al. (2000)

250 42Y McGregor et al. (2008)

84 173Y

Knauert et al., 2008; Knauert et al., 

2009

200 340Y

deNoyelles et al. 1989 Carney

1983

200 360Y deNoyelles et al. 1989

1000 21Y

Kosinski 1984; Kosinski and 

Merkle 1984

500 42Y Stay et al. 1989

430 53Y Stay et al. 1985

1000 30Y Johnson 1986

500 63Y

deNoyelles et al. 1982; deNoyelles 

et al. 1989

1000 42Y Stay et al. 1989

820 53Y Stay et al. 1985
500 365

Y

Carney 1983; Kettle et al. 1987; 

deNoyelles et al. 1989; deNoyelles 

et al. 1994

5000 12Y Brockway et al. 1984

100007Y Moorhead and Kosinski 1986

2036 51Y Diana et al. (2000)

10000 21Y

Kosinski 1984; Kosinski and 

Merkle 1984

5000 42Y Stay et al. 1989

3980 53Y Stay et al. 1985

1 18Y Lampert et al 1989

0.1 21Y Lampert et al 1989

ppendix D of the white paper. The data as scored would lead to a CE-LOC of 4ppb for the 60-day assessme

7-Day Test Concentration 14-Day Test Concentration 30-Day Test Concentration

0.50 0.25 0.12

2.07 1.04 0.48

2.86 1.43 0.67

5.00 2.50 1.17

8.00 4.00 1.87

9.60 4.80 2.24

10.00 5.00 2.33

25.00 12.50 5.83

28.57 14.29 6.67

30.00 15.00 7.00

42.86 21.43 10.00

50.00 25.00 11.67

57.14 28.57 13.33

107.14 53.57 25.00

120.00 60.00 28.00

120.00 60.00 28.00

400.00 200.00 93.33

428.57 214.29 100.00

32.91 16.46 7.68

171.43 85.71 40.00

11.43 5.71 2.67

Endpoints Normalized to Assessment Period

739.29 369.64 172.50

145.71 72.86 34.00

150.00 75.00 35.00

300.00 150.00 70.00

11.43 5.71 2.67

12.83 6.42 2.99

14.29 7.14 3.33

24.30 12.15 5.67

30.00 15.00 7.00

32.14 16.07 7.50

41.14 20.57 9.60

85.71 42.86 20.00

96.00 48.00 22.40

100.00 50.00 23.33

100.00 50.00 23.33

107.14 53.57 25.00

107.14 53.57 25.00

148.00 74.00 34.53
153.57 76.79 35.83

171.43 85.71 40.00

180.00 90.00 42.00

191.86 95.93 44.77

200.00 100.00 46.67

214.29 107.14 50.00

228.57 114.29 53.33

229.71 114.86 53.60

1042.86 521.43 243.33

300.00 150.00 70.00

330.00 165.00 77.00

392.86 196.43 91.67

401.29 200.64 93.63

468.00 234.00 109.20

600.00 300.00 140.00

600.00 300.00 140.00

636.00 318.00 148.40

640.00 320.00 149.33

857.14 428.57 200.00

1000.00 500.00 233.33

1011.00 505.50 235.90

1120.00 560.00 261.33

1224.00 612.00 285.60

5214.29 2607.14 1216.67

1371.43 685.71 320.00

1371.43 685.71 320.00

5142.86 2571.43 1200.00

1287.14 643.57 300.33

1428.00 714.00 333.20

1500.00 750.00 350.00

2076.00 1038.00 484.40

9714.29 4857.14 2266.67

10285.71 5142.86 2400.00

3000.00 1500.00 700.00

3000.00 1500.00 700.00

3255.71 1627.86 759.67

4285.71 2142.86 1000.00

4500.00 2250.00 1050.00

6000.00 3000.00 1400.00

6208.57 3104.29 1448.67
26071.43 13035.71 6083.33

8571.43 4285.71 2000.00

10000.00 5000.00 2333.33

14833.71 7416.86 3461.20

30000.00 15000.00 7000.00

30000.00 15000.00 7000.00

30134.29 15067.14 7031.33

2.57 1.29 0.60

0.30 0.15 0.07

or the 60-day assessment period as described in the presentations.

60-Day Test Concentration

0.06 AVERAGE 13.99 430.29 50

0.24

0.33 60-DAY No Effects Effects

0.58

0.93 Min 0.06 0.04 CE-LOC

1.12 Max 86.25 3515.67 4

1.17 5th percentile 0.26 1.51 5 4

2.92 10th percentile 0.43 3.55 10 4

3.33 20th percentile 1.08 12.00 20 4

3.50 50th percentile 5.00 74.20 50 4

5.00 95th percentile 49.33 2910.56 95 4

5.83

6.67

12.50

14.00

14.00

46.67 30-DAY No Effects Effects

50.00

3.84 Min 0.12 0.07 CE-LOC

20.00 Max 172.50 7031.33 8

1.33 5th percentile 0.52 3.03 5 8

Summary Data for Plotting on Figures

Percentile 

Rank

Percentile 

Rank

1.33 5th percentile 0.52 3.03 5 8

86.25 10th percentile 0.87 7.10 10 8

17.00 20th percentile 2.17 24.00 20 8

17.50 50th percentile 10.00 148.40 50 8

35.00 95th percentile 98.67 5821.12 95 8

1.33

1.50

1.67

2.84

3.50

3.75

4.80 14-DAY No Effects Effects

10.00

11.20 Min 0.25 0.15 For Plotting Distributions

11.67 Max 369.64 15067.14 CE-LOC 15

11.67 5th percentile 1.11 6.49 5 15

12.50 10th percentile 1.86 15.21 10 15

12.50 20th percentile 4.64 51.43 20 15

17.27 50th percentile 21.43 318.00 50 15
17.92 95th percentile 211.43 12473.83 95 15

20.00

21.00

22.38 7-DAY No Effects Effects

23.33

25.00 Min 0.50 0.30 For Plotting Distributions

26.67 Max 739.29 30134.29 CE-LOC 18

26.80 5th percentile 2.23 13.05 5 18

121.67 10th percentile 3.71 30.64 10 18

35.00 20th percentile 9.28 104.29 20 18

38.50 50th percentile 42.86 618.00 50 18

45.83 95th percentile 422.86 24385.77 95 18

46.82

54.60

70.00 Actual Conc. No Effects Effects

70.00

74.20 Min 0.50 0.10 For Plotting Distributions

74.67 Max 207.00 10000.00 CE-LOC 4

100.00 5th percentile 0.60 10.00 5 4

116.67 10th percentile 1.40 20.00 10 4

117.95 20th percentile 2.96 30.00 20 4

130.67 50th percentile 10.00 100.00 50 4

142.80 95th percentile 100.00 4898.00 95 4

608.33

160.00

160.00

600.00

150.17

166.60

175.00

242.20

1133.33

1200.00

350.00

350.00

379.83

500.00

525.00

700.00

724.33
3041.67

1000.00

1166.67

1730.60

3500.00

3500.00

3515.67

0.30

0.04

0.10

1.00

10.00

100.00

1000.00

10000.00

0 10 20 30 40 50 60 70 80

C

oncentration (ug/L)

Percentile Rank

Cosm Effects and No Effects Distribution Normalized to a 60

Day Duration. (Conc.*Duration/60)

g Distributions

Percentile Rank

10.00

100.00

1000.00

10000.00

C

oncentration (ug/L)

Cosm Effects and No Effects Distribution Normalized to a 30

Day Duration. (Conc.*Duration/30)
g Distributions

g Distributions

0.10

1.00

0 10 20 30 40 50 60 70 80

C

oncentration (ug/

Percentile Rank

100.00

1000.00

10000.00

100000.00

C

oncentration (ug/L)

Cosm Effects and No Effects Distribution Normalized to a 14

Day Duration. (Conc.*Duration/14)

1.00

10.00

100.00

0 10 20 30 40 50 60 70 80

C

oncentration (ug/L)

Percentile Rank

100000.00

Cosm Effects and No Effects Distribution Normalized to a 7

Day Duration. (Conc.*Duration/7)
1.00

10.00

100.00

1000.00

10000.00

0 10 20 30 40 50 60 70 80

C

oncentration (ug/L)

Percentile Rank

10000.00

Cosm Effects and No Effects Distribution Over Variable 

Durations. (Concentration Reported)

0.10

1.00

10.00

100.00

1000.00

10000.00

0 10 20 30 40 50 60 70 80

C

oncentration (ug/L)

Cosm Effects and No Effects Distribution Over Variable 

Durations. (Concentration Reported)
0 10 20 30 40 50 60 70 80

Percentile Rank
90 100

Normalized to a 60-

Effects

No Effects

CE-LOC

Normalized to a 30-

Effects

No Effects

CE-LOC
90 100

Normalized to a 14-

Effects

No Effects

CE-LOC

90 100

 Normalized to a 7-
90 100

Effects

No Effects

CE-LOC

on Over Variable 

ported)

90 100

on Over Variable 

ported)

Effects

No Effects

CE-LOC
90 100