#![allow(unused_imports)]
#![allow(non_snake_case, unused)]

use std::cmp::*;
use std::collections::*;
use std::ops::*;

// https://atcoder.jp/contests/hokudai-hitachi2019-1/submissions/10518254

macro_rules! eprint {
	($($t:tt)*) => {{
		use ::std::io::Write;
		let _ = write!(::std::io::stderr(), $($t)*);
	}};
}
macro_rules! eprintln {
	() => { eprintln!(""); };
	($($t:tt)*) => {{
		use ::std::io::Write;
		let _ = writeln!(::std::io::stderr(), $($t)*);
	}};
}
macro_rules! dbg {
	($v:expr) => {{
		let val = $v;
		eprintln!("[{}:{}] {} = {:?}", file!(), line!(), stringify!($v), val);
		val
	}}
}

macro_rules! mat {
	($($e:expr),*) => { Vec::from(vec![$($e),*]) };
	($($e:expr,)*) => { Vec::from(vec![$($e),*]) };
	($e:expr; $d:expr) => { Vec::from(vec![$e; $d]) };
	($e:expr; $d:expr $(; $ds:expr)+) => { Vec::from(vec![mat![$e $(; $ds)*]; $d]) };
}

macro_rules! ok {
	($a:ident$([$i:expr])*.$f:ident()$(@$t:ident)*) => {
		$a$([$i])*.$f($($t),*)
	};
	($a:ident$([$i:expr])*.$f:ident($e:expr$(,$es:expr)*)$(@$t:ident)*) => { {
		let t = $e;
		ok!($a$([$i])*.$f($($es),*)$(@$t)*@t)
	} };
}

pub fn readln() -> String {
	let mut line = String::new();
	::std::io::stdin().read_line(&mut line).unwrap_or_else(|e| panic!("{}", e));
	line
}

macro_rules! read {
	($($t:tt),*; $n:expr) => {{
		let stdin = ::std::io::stdin();
		let ret = ::std::io::BufRead::lines(stdin.lock()).take($n).map(|line| {
			let line = line.unwrap();
			let mut it = line.split_whitespace();
			_read!(it; $($t),*)
		}).collect::<Vec<_>>();
		ret
	}};
	($($t:tt),*) => {{
		let line = readln();
		let mut it = line.split_whitespace();
		_read!(it; $($t),*)
	}};
}

macro_rules! _read {
	($it:ident; [char]) => {
		_read!($it; String).chars().collect::<Vec<_>>()
	};
	($it:ident; [u8]) => {
		Vec::from(_read!($it; String).into_bytes())
	};
	($it:ident; usize1) => {
		$it.next().unwrap_or_else(|| panic!("input mismatch")).parse::<usize>().unwrap_or_else(|e| panic!("{}", e)) - 1
	};
	($it:ident; [usize1]) => {
		$it.map(|s| s.parse::<usize>().unwrap_or_else(|e| panic!("{}", e)) - 1).collect::<Vec<_>>()
	};
	($it:ident; [$t:ty]) => {
		$it.map(|s| s.parse::<$t>().unwrap_or_else(|e| panic!("{}", e))).collect::<Vec<_>>()
	};
	($it:ident; $t:ty) => {
		$it.next().unwrap_or_else(|| panic!("input mismatch")).parse::<$t>().unwrap_or_else(|e| panic!("{}", e))
	};
	($it:ident; $($t:tt),+) => {
		($(_read!($it; $t)),*)
	};
}


pub fn main() {
	let _ = ::std::thread::Builder::new().name("run".to_string()).stack_size(32 * 1024 * 1024).spawn(run).unwrap().join();
}

const MOD: u32 = 998244353;
const INF: i64 = std::i64::MAX/3;

#[derive(Clone, Copy)]
struct ModInt(u32);
 
impl std::ops::Add for ModInt {
    type Output = ModInt;
    fn add(self, rhs: ModInt) -> Self::Output {
        let mut d = self.0 + rhs.0;
        if d >= MOD {
            d -= MOD;
        }
        ModInt(d)
    }
}
 
impl std::ops::AddAssign for ModInt {
    fn add_assign(&mut self, rhs: ModInt) {
        *self = *self + rhs;
    }
}
 
impl std::ops::Sub for ModInt {
    type Output = ModInt;
    fn sub(self, rhs: ModInt) -> Self::Output {
        let mut d = self.0 + MOD - rhs.0;
        if d >= MOD {
            d -= MOD;
        }
        ModInt(d)
    }
}
 
impl std::ops::SubAssign for ModInt {
    fn sub_assign(&mut self, rhs: ModInt) {
        *self = *self - rhs;
    }
}
 
impl std::ops::Mul for ModInt {
    type Output = ModInt;
    fn mul(self, rhs: ModInt) -> Self::Output {
        ModInt((self.0 as u64 * rhs.0 as u64 % MOD as u64) as u32)
    }
}
 
impl std::ops::MulAssign for ModInt {
    fn mul_assign(&mut self, rhs: ModInt) {
        *self = *self * rhs;
    }
}
 
impl std::ops::Neg for ModInt {
    type Output = ModInt;
    fn neg(self) -> Self::Output {
        ModInt(if self.0 == 0 {0} else {MOD - self.0})
    }
}
 
/* 
impl std::fmt::Display for ModInt {
    fn fmt(&self, f: &mut std::fmt::Formatter<'_>) -> std::fmt::Result {
        write!(f, "{}", self.0)
    }
}
*/
 
#[allow(dead_code)]
impl ModInt {
    pub fn new(n: u32) -> ModInt {
        ModInt(n % MOD)
    }
    pub fn zero() -> ModInt {
        ModInt(0)
    }
    pub fn one() -> ModInt {
        ModInt(1)
    }
    pub fn pow(self, mut n: u32) -> ModInt {
        let mut t = ModInt::one();
        let mut s = self;
        while n > 0 {
            if n & 1 == 1 {
                t *= s;
            }
            s *= s;
            n >>= 1;
        }
        t
    }
    pub fn inv(self) -> ModInt {
        self.pow(MOD - 2)
    }
}

fn solve() {
	let (a,b,c,d) = read!(usize,usize,usize,usize);
	let mut dp = vec![vec![ModInt(0);d+1];c+1];
	dp[a][b] = ModInt(1);
	for i in a..c+1 {
		for j in b..d+1 {
			if i==a && j==b {
				continue;
			}
			dp[i][j] = dp[i-1][j]*ModInt(j as u32) + dp[i][j-1]*ModInt(i as u32) - 
			dp[i-1][j-1]*ModInt((j-1_usize) as u32) *ModInt((i-1_usize) as u32);
		}
	}
	println!("{}",dp[c][d].0);
}

fn run() {
    solve();
}


Measured memory_bytes: 37492