import java.io.IOException;
import java.io.InputStream;
import java.util.ArrayDeque;
import java.util.ArrayList;
import java.util.Arrays;
import java.util.HashMap;
import java.util.NoSuchElementException;
import java.util.PriorityQueue;
import java.util.concurrent.PriorityBlockingQueue;

public class Main {

    static final long DIV = 998244353l;

    public static void main(String[] args) {
        FastScanner sc = new FastScanner();
        int a = sc.nextInt();
        int b = sc.nextInt();
        int c = sc.nextInt();
        int d = sc.nextInt();

        // long[] ie = new long[10000];
        // for (int i = 1; i < ie.length; i++) {
        //     ie[i] = inverseElement(i, DIV);
        // }

        long[][] dp = new long[c+d-a-b+2][c-a+2];
        dp[1][1] = 1;
        for (int i = 2; i < dp.length; i++) {
            for (int j = 1; j < dp[0].length; j++) {
                long di = j+a-1;
                long dj = i-j+b;
                if(i-j <= d-b) dp[i][j] += dp[i-1][j] * di;
                dp[i][j] += dp[i-1][j-1] * dj;
                dp[i][j] -= dp[i-2][j-1] * (di-1) * (dj-1);
                if(dp[i][j] < 0){
                    dp[i][j] += (Math.abs(dp[i][j]) / DIV+1) * DIV;
                }
                dp[i][j] %= DIV;
            }
        }

        System.out.println(dp[c+d-a-b+1][c-a+1]);
    }

    public static long inverseElement(long a, long n){
        long b = n, u=1, v=0;
        while(b > 0) {
            long t = a/b;
            a -= t*b;
            u -= t*v;
            //swap
            t = a;
            a = b;
            b = t;
            t = u;
            u = v;
            v = t;
        }
        u = u % n;
        if(u < 0) u += n;
        return u;
    }

    private static class FastScanner {
        private final InputStream in = System.in;
        private final byte[] buffer = new byte[1024];
        private int ptr = 0;
        private int buflen = 0;

        private boolean hasNextByte() {
            if (ptr < buflen) {
                return true;
            } else {
                ptr = 0;
                try {
                    buflen = in.read(buffer);
                } catch (IOException e) {
                    e.printStackTrace();
                }
                if (buflen <= 0) {
                    return false;
                }
            }
            return true;
        }

        private int readByte() {
            if (hasNextByte())
                return buffer[ptr++];
            else
                return -1;
        }

        private static boolean isPrintableChar(int c) {
            return 33 <= c && c <= 126;
        }

        public boolean hasNext() {
            while (hasNextByte() && !isPrintableChar(buffer[ptr]))
                ptr++;
            return hasNextByte();
        }

        public String next() {
            if (!hasNext())
                throw new NoSuchElementException();
            StringBuilder sb = new StringBuilder();
            int b = readByte();
            while (isPrintableChar(b)) {
                sb.appendCodePoint(b);
                b = readByte();
            }
            return sb.toString();
        }

        public long nextLong() {
            if (!hasNext())
                throw new NoSuchElementException();
            long n = 0;
            boolean minus = false;
            int b = readByte();
            if (b == '-') {
                minus = true;
                b = readByte();
            }
            if (b < '0' || '9' < b) {
                throw new NumberFormatException();
            }
            while (true) {
                if ('0' <= b && b <= '9') {
                    n *= 10;
                    n += b - '0';
                } else if (b == -1 || !isPrintableChar(b)) {
                    return minus ? -n : n;
                } else {
                    throw new NumberFormatException();
                }
                b = readByte();
            }
        }

        public int nextInt() {
            long nl = nextLong();
            if (nl < Integer.MIN_VALUE || nl > Integer.MAX_VALUE)
                throw new NumberFormatException();
            return (int) nl;
        }

        public double nextDouble() {
            return Double.parseDouble(next());
        }
    }

}


Measured memory_bytes: 175140