#![allow(unused_imports, unused_macros)]

use kyoproio::*;
use std::{
    collections::*,
    io::{self, prelude::*},
    iter,
    mem::{replace, swap},
};

fn main() -> io::Result<()> {
    std::thread::Builder::new()
        .stack_size(64 * 1024 * 1024)
        .spawn(|| {
            let stdin = io::stdin();
            let stdout = io::stdout();
            run(KInput::new(stdin.lock()), io::BufWriter::new(stdout.lock()))
        })?
        .join()
        .unwrap();
    Ok(())
}

fn run<I: Input, O: Write>(mut kin: I, mut out: O) {
    macro_rules! output { ($($args:expr),+) => { write!(&mut out, $($args),+).unwrap(); }; }
    macro_rules! outputln {
        ($($args:expr),+) => { output!($($args),+); outputln!(); };
        () => { output!("\n"); if cfg!(debug_assertions) { out.flush().unwrap(); } }
    }

    const MOD: i64 = 998244353;
    let (a, b, c, d): (usize, usize, usize, usize) = kin.input();
    let mut dp = vec![[0; 3001]; c + 1];
    dp[a][b] = 1;
    for i in a..=c {
        for j in b..=d {
            if i == a && j == b {
                continue;
            }
            dp[i][j] = i as i64 * dp[i][j - 1] % MOD + j as i64 * dp[i - 1][j] % MOD;
            dp[i][j] += MOD - (i as i64 - 1) * (j as i64 - 1) * dp[i - 1][j - 1] % MOD;
            dp[i][j] %= MOD;
            /*
            if i == a {
                dp[i][j] = a as i64 * dp[i][j - 1] % MOD;
            } else if j == b {
                dp[i][j] = b as i64 * dp[i - 1][j] % MOD;
            } else {
                dp[i][j] = (i as i64 - 1) * (j as i64 - 1) * dp[i - 1][j - 1] % MOD;
                dp[i][j] += dp[i - 1][j] + dp[i][j - 1];
                dp[i][j] %= MOD;
            }
            */
        }
    }
    /*
    for i in 1..=c {
        for j in 1..=d {
            eprint!("{:3}", dp[i][j]);
        }
        eprintln!();
    }
    */
    outputln!("{}", dp[c][d]);
}

// -----------------------------------------------------------------------------
pub mod kyoproio {
    use std::io::prelude::*;
    pub trait Input {
        fn str(&mut self) -> &str;
        fn input<T: InputParse>(&mut self) -> T {
            T::input(self)
        }
        fn iter<T: InputParse>(&mut self) -> Iter<T, Self> {
            Iter(self, std::marker::PhantomData)
        }
        fn seq<T: InputParse, B: std::iter::FromIterator<T>>(&mut self, n: usize) -> B {
            self.iter().take(n).collect()
        }
    }
    pub struct KInput<R> {
        src: R,
        buf: String,
        pos: usize,
    }
    impl<R: BufRead> KInput<R> {
        pub fn new(src: R) -> Self {
            Self {
                src,
                buf: String::with_capacity(1024),
                pos: 0,
            }
        }
        pub fn src(&mut self) -> &mut R {
            &mut self.src
        }
    }
    impl<R: BufRead> Input for KInput<R> {
        fn str(&mut self) -> &str {
            loop {
                if self.pos >= self.buf.len() {
                    self.pos = 0;
                    self.buf.clear();
                    if self.src.read_line(&mut self.buf).expect("io error") == 0 {
                        return &self.buf;
                    }
                }
                let range = self.pos
                    ..self.buf[self.pos..]
                        .find(|c: char| c.is_ascii_whitespace())
                        .map(|i| i + self.pos)
                        .unwrap_or_else(|| self.buf.len());
                self.pos = range.end + 1;
                if range.end > range.start {
                    return &self.buf[range];
                }
            }
        }
    }
    pub struct Iter<'a, T, I: ?Sized>(&'a mut I, std::marker::PhantomData<*const T>);
    impl<'a, T: InputParse, I: Input + ?Sized> Iterator for Iter<'a, T, I> {
        type Item = T;
        fn next(&mut self) -> Option<T> {
            Some(self.0.input())
        }
    }
    pub trait InputParse: Sized {
        fn input<I: Input + ?Sized>(src: &mut I) -> Self;
    }
    impl InputParse for Vec<u8> {
        fn input<I: Input + ?Sized>(src: &mut I) -> Self {
            src.str().as_bytes().to_owned()
        }
    }
    macro_rules! from_str_impl {
        { $($T:ty)* } => {
            $(impl InputParse for $T {
                fn input<I: Input + ?Sized>(src: &mut I) -> Self {
                    src.str().parse::<$T>().expect("parse error")
                }
            })*
        }
    }
    from_str_impl! {
        String char bool f32 f64 isize i8 i16 i32 i64 i128 usize u8 u16 u32 u64 u128
    }
    macro_rules! tuple_impl {
        ($H:ident $($T:ident)*) => {
            impl<$H: InputParse, $($T: InputParse),*> InputParse for ($H, $($T),*) {
                fn input<I: Input + ?Sized>(src: &mut I) -> Self {
                    ($H::input(src), $($T::input(src)),*)
                }
            }
            tuple_impl!($($T)*);
        };
        () => {}
    }
    tuple_impl!(A B C D E F G);
    #[macro_export]
    macro_rules! kdbg {
        ($($v:expr),*) => {
            if cfg!(debug_assertions) { dbg!($($v),*) } else { ($($v),*) }
        }
    }
}


Measured memory_bytes: 71512