Evaluate the truthfulness of this statement:
"The membrane potential is the difference in electrical charge between the inside and outside of a cell membrane. It is generated by the movement of ions such as sodium (Na+), potassium (K+), and chloride (Cl-) across the cell membrane through ion channels. In the virtual experiment, we explored this concept further by examining action potential.

The action potential is a brief electrical signal that is generated by neurons and muscle cells. It is an all-or-nothing event that occurs when the cell's membrane potential rapidly depolarizes and then repolarizes back to its resting potential. In other words, we can describe it as a temporary membrane potential reversal. Action potentials are essential for cell-to-cell communication in neurons, where they propagate signals along the axon toward other neurons or cells at synapses. For example, action potentials are the first step in the contraction process in muscle cells.

The resting membrane potential of neurons is typically around -70 mV relative to the outside of the cell. However, what could be the reason for this? 

The cell membrane is selectively permeable to different ions, meaning that some ions can move more easily across the membrane than others. For example, in neurons, the cell membrane is more permeable to potassium K+ ions than Na+ ions. At rest, the concentration of K+ ions is also higher inside the cell than outside, while Na+ ions are higher outside the cell than inside. This concentration gradient drives K+ ions out of the cell and Na+ ions into the cell. However, the membrane's selective permeability to these ions also means that K+ ions are more likely to move out of the cell than Na+ ions are to move into the cell, creating a net negative charge inside the cell and a net positive charge outside the cell.

In addition to the concentration gradient, the cell membrane also contains ion channels that allow ions to move across the membrane in response to changes in the membrane potential. Therefore, the resting membrane potential of neurons at -70 mV is mainly determined by the balance between the concentration gradient and the membrane's selective permeability to different ions, as well as the activity of ion channels that allow ions to move across the membrane in response to changes in the membrane potential.

Finally, dramatically increasing or decreasing the membrane potential can also lead to changes in the neuron's excitability and the ability to generate action potentials. For example, if the membrane potential becomes more positive (depolarization), it can cause voltage-gated sodium channels to be open, allowing positively charged sodium ions to rush into the cell. This can further depolarize the membrane potential and trigger an action potential if the threshold potential is reached. On the other hand, if the membrane potential becomes more negative (hyperpolarization), it can make it more difficult for voltage-gated sodium channels to open and generate an action potential.

In some cases, very large changes in membrane potential can cause cell damage or death, especially if the change is sustained over a long period. For instance, excessively depolarizing the membrane potential can lead to an influx of calcium ions, triggering cell death pathways. In contrast, excessive hyperpolarization can inhibit normal cell function and cause the neuron to become unresponsive to incoming signals."