To create individuals with neko-like characteristics, specific genes must be edited. These genes can be classified into different groups depending on the function they serve in the development of specific traits.

Ear shaping:
- Wnt3a gene, which affects the formation of the spinal cord and peripheral nervous system, plays a significant role in the development of feline-like ears in humans. (Reference: “Wnt3a regulates peripheral neuropathy density and shape;” Lin et al., 2015)

Tail shaping:
- HOXD13 gene is crucial for the development of tail-like structures at the base of the spine. (Reference: “An essential role for homeobox genes in vertebrate axial patterning? The HoxD example;” Duboule and Dolle, 1989)

Limb and spine development:
- FGFR2 (fibroblast growth factor receptor 2) gene and FGF4 (fibroblast growth factor 4) gene contribute to bone growth in limbs and spine structures. (Reference: “Fibroblast growth factor signal regulation in skeletal development and disease;” Ornitz and Marie, 2015)
- SOX9 gene plays a critical role in the development of cartilage and bone, allowing for structural changes in the limbs that promote flexibility and articulation abilities. (Reference: “The role of Sox9 in cartilage formation and maintenance;” Lefebvre and Dvir-Ginzberg, 2017)
- TBXT gene contributes to the formation of the mesoderm layer during embryonic development, which is essential for axial skeleton development. (Reference: “Mesoderm formation in xenopus;” Harland and Grainger, 2011)

Hair and fur pattern:
- ASIP (agouti signaling protein), MC1R (melanocortin 1 receptor), and TYRP1 (tyrosinase-related protein 1) genes are involved in the development of hair and fur patterns, which are modified to resemble that of house cats. (Reference: “Modulating pigmentation through signaling crosstalk;” Sundberg and King, 2019)
- BMP2 (bone morphogenetic protein 2) gene impacts hair follicle growth and regeneration, enabling the growth of hair or fur on the tail and ears. (Reference: “Bone morphogenetic proteins: From structure to clinical use;” Wang et al., 2016)
- EDAR gene is essential for the development of hair, teeth, and skin, allowing changes in hair type and distribution to create a fur-like coat resembling the exterior of felines. (Reference: “The great beauty of EDAR;” Kamberov and Sturm, 2018)

Behavior:
- TPH2 (tryptophan hydroxylase 2) gene contributes to serotonin production in the brain, resulting in calmer and more docile behavior. (Reference: “Genetic variation in TPH2 associates with paranoid ideation through increasing threat-related amygdala reactivity;” Kuhn et al., 2017)

Eye appearance:
- Pax6 gene plays a crucial role in the embryonic development of the eye, including iris formation, and can be edited to produce a unique elongated pupil shape. (Reference: “Pax6: A developmental gene essential for optic cup formation and eye development;” Ashery-Padan and Gruss, 2001)

Skin and eye color:
- SLC45A2 gene is involved in melanin production, which can be edited to produce lighter skin and eye color. (Reference: “Genetic determinants of human pigmentation: From genes to genomes;” Sturm, 2009)

It is important to note that humans do not naturally possess the genetic makeup for developing cat ears and tails, and these traits must be created through gene editing technologies. The genes involved in creating neko-like individuals have different characteristics and regulations than those found in animals. When utilizing genetic technologies for aesthetic purposes, ethical guidelines must be followed, and potential long-term consequences must be studied and monitored.

sort the genes in this text by importance (changes in the first gene will lead to the desired result with a higher probability than in the last one), add new genes if necessary, rewrite the text, add as much new and useful information for this task as possible