Pretend you are a teacher preparing a quiz for the text I will provide. 
            Each quiz question should follow the format below. 
            Ensure that you carefully recheck the questions and answers for accuracy. 
            The output should be a ready-to-use list of dictionaries for the Python eval function:

            [

                    "question": "WRITE THE QUESTION HERE",
                    "options": ["A) OPTION_1", "B) OPTION_2", "C) OPTION_3", "D) OPTION_4"],
                    "answer": INDEX_OF_CORRECT_ANSWER_IN_OPTIONS_LIST,
                    "explanation": "EXPLAIN WHY THE ANSWER IS CORRECT"

            ]

            Text:
            nary retention and serve constipation warrant immediate medical attention. 
3. The Alpha-adrenergic blockade can produce postural-orthostatic hypotension 
and tachycardia. 
Serious side effects: 
Cardiovascular, dysthymias, tachycardia, myocardial infarction, heart block, 
cardiac disease. 
 
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                                     B) The second line agent: 
Monoamine oxidase inhibitors (MAOIs) 
 Mechanism of actions: 
The monoamines oxide is responsible for breakdown certain brain amines 
such as norepinephrine, serotonin, dopamine and tyramine. When a person takes 
MAOI these amines do not break down and there is an increase of neurotransmitters 
(norepinephrine, serotonin) available for synaptic release. This increase of 
neurotransmitters can elevate mood of depressed person.  
The increase in on the other hand poses a problem. When mine tyramine increase 
and is not broken by MAO, this increase can lead to high blood. 
The most common drugs of (MAOIs):  
- Phenelzine (Nardil) 
- Isocarboxazid (Marplan) 
- Tranylcypromine sulfate (Parnate).  
Indication: 
- MOAIs are particularly effective for people with a typical depression, panic 
disorder and social phobia. 
Contraindications: 
- Cerebrovascular disease. 
- Hypertension and congestive heart failure. 
- Liver disease. 
12 
 
- Foods containing tyramine, tryptophan, and dopamine. 
- Recurrent or serve headaches. 
- Children younger than16 years old. 
Side effect of MOIs.   
The most common side effects of MAOIs include:  
• Orthostatic hypotension 
• Dry mouth 
• Nausea, diarrhea or constipation 
• Headache 
• Drowsiness, Dizziness or lightheadedness  
• Insomnia 
• Skin reaction. 
Other possible side effects include : 
• Involuntary muscle jerks 
• Low blood pressure 
• Reduced sexual desire or difficulty reaching orgasm 
• Sleep disturbances 
• Weight gain 
• Difficulty starting a urine flow 
• Muscle aches 
• Prickling or tingling sensation in the skin (paresthesia). 
 
 
 
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Hypertensive crisis   
Is the most severe side effect. A sudden severe increase in blood pressure caused by high 
tyramine level, as accumulation of these substance Triggers the release of norepinephrine and 
hypertensive crisis may occur. intracranial hemorrhage and death may result. 
Signs and symptoms of hypertensive crisis: 
• Sudden elevation of blood pressure higher than (170/110 mmHg.) 
• Explosive occipital headache 
. 
• Arrhythmia and Intra-cerebral hemorrhage.   
• Head and face flushed and feel 'full 
.' 
• Palpitation and chest pain 
. 
• Sweating, fever, nausea, and vomiting 
. 
Treatment of hypertensive crisis: 
• Stop MAOIs doses. 
• Monitor vital signs frequently. 
• Administer short acting antihypertensive medications as ordered by physician. 
• Do not lie down. 
• Manage fever by external cooling technique. 
• Evaluate diet adherence and teaching. Dilated pupil and photophobia. 
• An MAOI-induced hypertensive crisis can be treated with alpha adrenergic antagonists 
such as phentolamine or e

            Quiz: