Pretend you are a teacher preparing a quiz for the text I will provide. 
            Each quiz question should follow the format below. 
            Ensure that you carefully recheck the questions and answers for accuracy. 
            The output should be a ready-to-use list of dictionaries for the Python eval function:

            [

                    "question": "WRITE THE QUESTION HERE",
                    "options": ["A) OPTION_1", "B) OPTION_2", "C) OPTION_3", "D) OPTION_4"],
                    "answer": INDEX_OF_CORRECT_ANSWER_IN_OPTIONS_LIST,
                    "explanation": "EXPLAIN WHY THE ANSWER IS CORRECT"

            ]

            Text:
            mm3. 
v They are synthesized in the bone marrow. Their life span ranges from hours 
to one day 
v There are 3 types of the granular leukocytes neutrophil, eosinophil and 
basophils 
v There are 2 types of the agranular leukocytes; lymphocytes and the 
monocytes 
30 
 
v 
 
Function of white blood cells 
Neutrophils 
Esinophil 
Basophil 
Monocyte 
Lymphocyte: 
(first line of 
defense )  
anti-
inflammatory 
against 
bacterial 
infection by 
phagocytosis 
body defense 
against 
parasitic 
infestation 
Anti-
allergic 
CONTAIN  
HISTAMINE 
anti-
inflammatory 
against 
bacterial 
infection by 
phagocytosis 
(macrophage): 
(very strong) 
second line 
(malaria, 
brucllosis) 
B lymphocyte and 
T lymphocyte 
31 
 
 
(formation of 
antibodies) 
 
 
Red blood cells (RBCs) 
 
 
 
• RBCs are non-nucleated circular biconcave discs. 
• The normal RBCs count is 5 million/ mm3. 
 
The life span of the RBCs is 120 days formed in bone marrow  
 
 
 
 
 
 
 
 
 
32 
 
 
Erythropoiesis (Formation of the RBCs) 
 
• In adult life, the RBCs are formed in the bone marrow. 
 
 
 
 
 
33 
 
Functions of the RBCs:- 
A- Functions of the membrane 
1. Allow passage of RBCs through narrow capillaries (Plastic not elastic) 
2. The biconcave membrane gives large surface area for gas exchange  
3. Has selective permeability to ions. 
4. Keeps HB and carbonic anhydrase (CA) enzyme inside them. 
B- Functions of haemoglobin  
1. Carriage of gases 
2. Buffering action 
 
Anemias 
Definition:- decrease of the number of the RBCs or decrease heamoglobin 
percent than normal. 
 
 
34 
 
• Normal Hb% in male 13-16 gm/dl  
                          female 12-14 gm/dl  
Types of anemia  
Anemia can be classified according to the size and Hb content of each RBC 
to:  
1. Normocytic normochromic  
2. Microcytic hypochromic  
3. Macrocytic anemia 
 
 
Causes of normocytic normochromic anemia                            
1-Aplastic anaemia:-- Toxins , drugs and irradiation. 
2-Haemolytic anaemia as thalassemias and Sickle cell anemia 
3-Hemorrhagic anemia 
35 
 
Causes of microcytic hypochromic  
1- Chronic blood loss as in piles, bleeding peptic ulcer and excessive 
menestrutaion    
2-Deficiency anaemias as Iron Deficiency 
Causes of macrocytic anemia 
1-Pernicious anaemia due to deficiency of vit B12. 
2-Folic acid deficiency anaemia. 
 
 
Diagnosis the type of anemia  
MCV (80:100 micron) 
MCH (25:35 picogram) 
MCHC (32: 38 %)  
1. If less than normal is Microcytic hypochromic  
2. If normal is Normocytic normochromic  
3. If more than normal is Macrocytic anemia 
 
Polycythaemia 
Definition:- 
It is increased number of RBCs due to excess production rate. 
Primary polycythemia  
It’s a blood cancer that begins in the marrow of your bones, the soft center 
where new blood cells grow.  
Number of cells are more than 12X106 /ml  
Secondary polycythemia  
36 
 
It occurs whenever the tissues become hypoxic as in obstructive lung diseases 
and in subjects living at high altitudes. Number of cells 

            Quiz: