User: 

You are given access to make searches on the Internet. The format for making a search is:
1. After the user sends a message, you will decide whether to make a search. If you choose to make a search, you will output a single message, starting with the word <web_search>, followed by ONLY your web search query. After your search query, you must output the token </web_search> to denote the end of the search query. Keep your search query concise.
2. The system will then append the web search results at the end of the user message, starting with the token <web_search_results>. Take note that the user CANNOT SEE the content after <web_search_results> - YOU should use these results appropriately to improve your response. Additionally, If the web search results are already present in the user's message, then you MUST NOT request another web search.

IMPORTANT! You should choose to search the web ONLY if ANY of the following circumstances are met:
1. User is asking about current events or something that requires real-time information (news, sports scores, 'latest' information, etc.)
2. User is asking about some term you are unfamiliar with (e.g. if it's a little-known term, if it's a person you don't know well, etc.)
3. User is asking about anything that involves numerical facts (e.g. distances between places, population count, sizes, date and time, etc.)
4. User explicitly asks you to search or provide links to references.
If the user's query does NOT require a web search, YOU MUST NEVER run one for no reason. However, you must not refuse to search the web if the user asks you to do so.
If you are highly unsure about whether to make a search (e.g. if the user's query is vague or if you think you are unfamiliar with the query to a certain extent), you may directly ask the user for clarification.

When using web search results, you are encouraged to cite references where appropriate, using inline links in standard markdown format.
You are also allowed to make use of web search results from previous messages, if they are STRONGLY RELEVANT to the current message.

When you are not running a web search, respond completely as per normal - there is NO NEED to mention that you're not searching. 
Remember that you MUST NOT make up any false information.
Assistant: Understood. I will strictly follow these instructions in this conversation.
User: what is a substrate?
Assistant: A substrate generally refers to a surface or material upon which an organism grows, a reaction occurs, or an object is built. Its meaning can vary depending on the context:

1. **Biology**: In biology, a substrate is the surface or medium that supports the growth of organisms, such as soil for plants or a surface for microorganisms.
2. **Chemistry**: In chemistry, a substrate is a substance that undergoes a chemical reaction, often interacting with a catalyst or enzyme.
3. **Materials Science**: In the context of materials, a substrate can refer to the base material onto which other materials are applied, such as in electronics where a semiconductor might be built on a substrate.

If you have a specific context in mind, please let me know!
User: in biology is it the same thing as a reactent?
Assistant: In biology, a substrate and a reactant are related but distinct concepts:

1. **Substrate**: In biological terms, a substrate typically refers to the substance or surface on which an organism lives, grows, or interacts. For example, in enzymatic reactions, the substrate is the specific reactant that an enzyme acts upon. The enzyme binds to the substrate to facilitate the reaction.

2. **Reactant**: A reactant is any substance that participates in a chemical reaction. In biological reactions, reactants include substrates along with other molecules involved in the process.

So, while all substrates used in enzymatic reactions can be considered reactants, not all reactants are substrates in a biological context. The term "substrate" emphasizes the role of the substance in conditions like enzyme-substrate interactions.
User: sorry i meant in chemistry
Assistant: In chemistry, the terms **substrate** and **reactant** can also have specific meanings, though they are related:

1. **Substrate**: In the context of chemical reactions, particularly in the realm of biochemistry, a substrate is the substance that an enzyme acts upon. The substrate binds to the enzyme, leading to a chemical reaction that converts it into products. Substrates are often specific to the enzymes they interact with.

2. **Reactant**: A reactant is a broader term that refers to any substance consumed or transformed in a chemical reaction. This includes substrates and any additional compounds that may be involved in the reaction.

In summary, while all substrates can be classified as reactants in a chemical process, not all reactants are substrates. The distinction often lies in the context—substrate emphasizes the interaction with an enzyme, while reactant is a general term for any substance undergoing change in a reaction.
User: What is a product then?
Assistant: In chemistry, a **product** refers to the substances that are formed as a result of a chemical reaction. When reactants undergo transformations due to a chemical reaction, they yield new substances called products. 

Here's a breakdown of the concept:

1. **Formation**: Products are created when reactants react together. For example, in the reaction of hydrogen and oxygen to form water, water is the product.

2. **Chemical Equations**: In a chemical equation, the reactants are typically shown on the left side, while the products are shown on the right. For example, in the equation:
   \[
   2H_2 + O_2 \rightarrow 2H_2O
   \]
   Hydrogen (\(H_2\)) and oxygen (\(O_2\)) are the reactants, and water (\(H_2O\)) is the product.

3. **Characteristics**: Products have different properties from the reactants. This change in properties is a result of the rearrangement of atoms during the chemical reaction.

In conclusion, products are essential components of chemical reactions, resulting from the transformation of reactants through various processes.
User: what is the active site on an enzyme?
Assistant: