Please revise the following paragraphs：“A variety of cardiovascular diseases can lead to vascular dementia. Subclinical cerebral white matter lesions and microinfarcts and multiple infarcts are the most common causes of VCI, and cerebral haemorrhage, cerebral haemorrhage (ICH) and cerebral micro-haemorrhage are also associated with cognitive impairment and dementia. In a comparison of 71 stroke patients with 36 normal subjects of the same age, extensive structural degeneration of the white matter of the entire brain occurred in stroke patients. Starting three months after stroke, the researchers observed a decrease in the density of fibres associated with cognitive function in the white matter of the patients' brains, a significant decrease in the cross-sectional area of fibre tracts, and a decrease in the patients' cognitive abilities, particularly visuospatial processing, processing speed, language and recognition memory. If there is a sudden onset of cognitive impairment with neurological impairment and the patient has not experienced cerebral thrombosis for a long time, it may be due to a cardiogenic stroke. Clinical statistics show that cardiogenic strokes account for about 1/4-1/3 of all strokes and are most commonly caused by reduced cerebral perfusion due to cardiac systolic dysfunction such as heart failure, ischaemic heart disease and atrial fibrillation. Reduced cerebral perfusion-induced ischemia and hypoxia can over-activate neuroinflammation and cause apoptosis. Inhibition of the mir -93-mediated TLR4/MyD88/NF-B inflammatory signalling pathway through acupuncture can reduce vascular cognitive impairment. Oxidative stress has also been shown to play an important role in the progression of VaD, with neuronal Nox1 (NADPH oxidase 1) being activated to produce an oxidative response in response to chronic cerebral ischaemia, leading to oxidative stress death in the corresponding hippocampal neurons, while PGC-1α (Peroxisome
	The upregulation of PGC-1α (proliferator-activated receptor-γ co-activator-1α) promotes the expression of mitochondrial antioxidants and uncoupling proteins (UCPs), reduces the production of reactive oxygen species (ROS) and improves cognitive impairment caused by chronic cerebral hypoperfusion. Cerebral amyloid angiopathy is a common small vessel disease caused by the progressive deposition of β-amyloid in the cerebral vascular wall, and its pathogenesis differs from that of AD caused by peripheral β-amyloid deposition in the vasculature, which leads to vascular dementia by activating vascular damage pathways that impair vascular physiology or activate vascular inflammatory pathways that increase the risk of stroke. microRNAs play an important role in the pathology of VID. A number of studies have shown that microRNA alterations accompany the pathogenesis of VID, and conversely that modulation of microRNAs by drugs or therapy can improve VID. Yali and colleagues found that aerobic exercise reduced miR-186 expression and inhibited neuronal apoptosis to alleviate vascular cognitive impairment, while in mice knocking out MicroRNA-15a/16-1 gene in mice slowed cognitive dysfunction in VID mice, and recently researchers have bioinformatically analyzed four microRNAs (miR-27a-3p, miR-146a-5p, miR-335-5p, and miR-129-2-3p) associated with vascular dementia. be a potential target for the development of new diagnostic and therapeutic approaches to VID.”