The brigade was disbanded after the war along with the whole of the Territorial Force which was reformed in 1920 as the Territorial Army. The brigade was also reformed in 1939 just before the Second World War as the war clouds with Nazi Germany were fast approaching and war was becoming increasingly likely. The brigade was reformed as the 199th Infantry Brigade and was again assigned to the 66th (East Lancashire) Division. However, after the British Expeditionary Force was evacuated from France, the 66th Division was disbanded in June 1940. The brigade was later assigned to the 55th (West Lancashire) Infantry Division, serving with it for the rest of the war, and in 1944, was redesignated the 166th Infantry Brigade. The brigade saw many changes in its infantry battalions throughout the war and never saw active service outside the United Kingdom.