Moore directed the 2007 film, "Sicko", about the American health care system, focusing particularly on the managed-care and pharmaceutical industries. At least four major pharmaceutical companies—Pfizer, Eli Lilly, AstraZeneca, and GlaxoSmithKline—ordered their employees not to grant any interviews or assist Moore. According to Moore in a letter on his website, "roads that often surprise us and lead us to new ideas—and challenge us to reconsider the ones we began with have caused some minor delays." The film premiered at the Cannes Film Festival on May 19, 2007, receiving a lengthy standing ovation, and was released in the U.S. and Canada on June 29, 2007. The film is currently ranked the tenth highest grossing documentary of all time and received an Academy Award nomination for Best Documentary Feature.