The one trophy that evaded Alex Sandro was the UEFA Champions League, which saw his side lose 4–1 in the final to holders Real Madrid at the Millennium Stadium in Cardiff. Alex Sandro played a key role in Mario Mandžukić's temporary equaliser in the first half, supplying the cross that was chested down to the Croatian by Gonzalo Higuaín. In the second half, however, Alex Sandro's and his teammates' performances were less convincing, and one of Alex Sandro's mistakes led to a goal from his former Brazil Under-20 and Porto colleague Casemiro.