On January 20, 2016, Drummond set an NBA record for free throws missed in a game with 23, surpassing the previous record of 22 set by Wilt Chamberlain on December 1, 1967. He also set a career high and franchise record by attempting 36 free throws. On January 28, Drummond earned his first NBA All-Star Game selection as a reserve for the Eastern Conference in the 2016 NBA All-Star Game. During the All-Star weekend, he also participated in the Slam Dunk Contest. On February 27, he recorded his league-leading 50th double-double of the season with 15 points and 17 rebounds in a 102–91 win over the Milwaukee Bucks. On March 2, Drummond recorded nine points and 14 rebounds against the San Antonio Spurs, ending his career high and the league's season high of consecutive double-doubles at 13 straight. The Pistons finished the regular season as the eighth seed in the Eastern Conference with a 44–38 record, earning a playoff berth for the first time since 2009. They went on to be swept in their first-round match-up against the eventual NBA champions, the Cleveland Cavaliers, in a highly competitive series.