On December 15, 2020, Antetokounmpo re-signed with the Bucks, coming to terms on a 5-year, $228 million extension, the largest in league history. At the 2021 All-Star Game, he played on the team captained by James and scored 35 points on a perfect 16-of-16 shooting from the field to lead the team to a 170–150 win and became the first non-American to win the All-Star MVP.