In the South Korean context, a re-evaluation for listed drugs is a practical policy instrument that can make a major contribution to the rationalization of drug spending. In addition, the impact would be significant as it would affect the list and prices of new drugs, as the listed drugs could become the comparators for new drugs in the economic evaluation. Furthermore, in South Korea, "People don't know the effects of cannabis, because they have never experienced it." There is an enormous stigma surrounding drugs. This has to do with the cultural context of South Korea. The country is enormously influenced by the consequences of the opium war between Great Britain and China. Since then, there has been a huge taboo on all kinds of drugs in Korea.