For the 2008 regular season, Cora played in 75 games, batting .270 with no home runs and 9 RBI. He appeared in four postseason games; two games of the 2008 ALDS, which Boston won, and two games of the 2008 ALCS, which Boston lost. He batted 4-for-26 (.154) with no home runs and one RBI. These games were the final postseason appearances for Cora as a player.