She was active in the suffrage movement and the temprance movement. In 1889 Walkington took part in the "Congres International des Oeuvres et Institutions Feminines" in connection with the Paris Exhibition as part of the Dublin Women's Suffrage Committee. She founded the Belfast Women's Suffrage Society in 1912 with Miss Montgomery, which became the Women's Political League in 1918, and helped start the Irish Women's Suffrage Federation. She also served as secretary for the Belfast chapter of the Church League for Women's Suffrage and worked with the Irish Women's Temperance Union. She was working to form a women's voters union shortly before she died.