The major engagements of the war occurred at Rouen, Dreux, and Orléans. At the Siege of Rouen (May–October 1562), the crown regained the city, but Antoine of Navarre died of his wounds. In the Battle of Dreux (December 1562), Condé was captured by the Guises, and Montmorency, the governor general, was captured by those opposing the crown. In February 1563, at the Siege of Orléans, Francis, Duke of Guise, was shot and killed by the Huguenot Jean de Poltrot de Méré. As he was killed outside of direct combat, the Guise considered this an assassination on the orders of the duke's enemy, Admiral Coligny. The popular unrest caused by the assassination, coupled with the resistance by the city of Orléans to the siege, led Catherine de' Medici to mediate a truce, resulting in the Edict of Amboise on 19 March 1563.