On Thanksgiving in the early 1980s, Marty Pascal returns to his family's home in McLean, Virginia, to visit his mother, younger brother Anthony, and twin sister Jackie-O, who adopted her name as a result of her obsession with Jacqueline Kennedy Onassis. Marty has brought with him his new fiancé Lesly, shocking the family with the revelation that he is engaged. The news destabilizes Jackie-O, who has recently been released from a psychiatric hospital. As the play progresses, it transpires that Marty and Jackie-O are involved in an incestuous relationship; their father left the family the day of John F. Kennedy's assassination, and as teenagers Jackie-O and Marty would re-enact the assassination as a form of ritualistic foreplay. The play concludes with Marty and Jackie-O again re-enacting the assassination, though Jackie-O intentionally uses a gun loaded with real bullets instead of the previously used blank cartridges, killing Marty.