Bernardeschi scored his first goal of the 2018–19 season in Juventus's opening Serie A match on 18 August 2018, netting the winner in a 3–2 away victory over Chievo in injury time. On 12 March 2019, Bernardeschi made a great sprint that resulted in a penalty kick in a 3–0 win over Atlético Madrid in the Champions League. In that match, he also made an assist.