John Axouch was John II's closest adviser and was his only intimate friend. Axouch was a Turk captured as a child at the Siege of Nicaea, who had been given as a gift to John's father. Emperor Alexios had thought him a good companion for his son, and so he had been brought up alongside the prince in the imperial household. Axouch was immediately appointed Grand Domestic (in Greek: μέγας δομέστικος, "megas domestikos"), upon the accession of John II. The Grand Domestic was the commander in chief of the Byzantine armies. It has been suggested that references to Axouch's possession of the imperial seal early in the reign of John's successor Manuel I meant that he was, in addition to his military duties, the head of the civil administration of the Empire. This was an unofficial position known at the time as the "mesazon", and equivalent to a vizier or 'prime-minister.' Such an appointment was remarkable, and a radical departure from the nepotism that had characterised the reign of Alexios I. The imperial family harboured some degree of resentment at this decision, which was reinforced by the fact that they were required to make obeisance to John Axouch whenever they met him.