During the 2014 Scottish independence referendum, Temerko publicly supported the campaign for Scotland to remain in the United Kingdom. He has publicly voiced his support for Britain to remain in the European Union. After the Referendum, Temerko advocated for a soft Brexit or even a general election, rather than a "no-deal" Brexit. "Le Monde" quoted Temerko as stating that the most sensible solution for London would be to stop the Brexit process and support the French through reforming the European Union. In August 2019, Temerko suggested that an extension of Article 50 or a second referendum were the only option to avoid the "unfolding travesty" of a no-deal exit on 31 October.