The JASSM was first employed during the 14 April 2018 missile strikes against Syria during the Syrian Civil War. Two B-1 Lancers fired a total of 19 JASSMs as part of strikes against three Syrian government alleged chemical weapons targets. All 19 JASSM missiles were fired at the Barzah Research Center, which was destroyed in the strike. According to Russian state media, two missiles that failed to detonate were found by the Syrian Arab Army and transferred to Russia on 18 April for study - no evidence of this claim has been provided; initial reports had stated JASSM-ER missiles were used, but it was later clarified that baseline JASSM models were employed.