Mikutina made her World debut in Stockholm at the 2021 World Championships in late March. She skated clean in her short program at the event to score a new personal best, topping her previous score by over 14 points, and qualified to the free skate in eleventh place. She then placed seventh in the free skate and finished eight overall. Mikutina's placement in the top ten qualified a place for Austria at the 2022 Winter Olympics, as well as the possibility of a second berth, and two placements at the following year's world championships. It was the best result for an Austrian lady since Julia Lautowa's eighth place in 1997.