As the fifth seed in the ACC Tournament, Duke beat NC State in the second round but lost to Notre Dame in the quarterfinals. In the 2016 NCAA Tournament, Duke was awarded a fourth seed and won their first round match-up against UNC Wilmington. After beating Yale in the second round, Duke was defeated in the Sweet 16 by Oregon despite 24 points from Ingram. In 36 games for Duke in 2015–16, Ingram averaged 17.3 points, 6.8 rebounds, and 2.0 assists in 34.6 minutes per game, while shooting 44.2% from the field, 41.0% from three-point range and 68.2% from the free throw line. He finished the tournament averaging 23.0 points to go along with 6.3 rebounds and 2.7 assists in the three games. He subsequently earned ACC Rookie of the Year honors and AP All-American honorable mention. Ingram had one of the best seasons ever for a young player at Duke, ranking in the top 3 among the school's all-time freshman leaders in scoring (third), three-pointers (second) and 20-point games (tied for second). On April 4, 2016, Ingram declared for the 2016 NBA draft, forgoing his final three years of college eligibility.