For the first few years of its existence, the "Collegium Melitense" had no dedicated premises and classes were held at a house in Valletta which had been provided by Bishop Gargallo. Construction of a Jesuit church in Valletta had commenced in 1592, and construction of an adjacent building to house the college began in 1595. The college moved into the new building in 1597, although construction works continued until 1602. The college and the church were damaged in a gunpowder factory explosion in 1634, and both buildings were subsequently remodelled. They also suffered some damage in an earthquake in 1693 but they were also repaired.