In 2014, Rose was created a life peer and took a seat on the Conservative benches in the House of Lords. In October 2015, Rose was appointed chair of Britain Stronger in Europe, the official remain campaign in the 2016 referendum on the United Kingdom's membership of the European Union. After stating to a select committee in March 2016 that wages would go up should Britain leave the European Union, his public role was allegedly limited for the rest of the campaign. In 2019, Rose dismissed calls for a second referendum, stating that he 'believes in a democratic process', despite being a Remainer.