The first battle experience Wedel's regiment had in the Seven Years' War occurred at the Battle of Prague on 6 May 1757. Six days later, he was appointed regimental commander. He was present at the Battle of Rossbach. At Leuthen, he led his regiment on the difficult march to flank the Austrian left; by 1 p.m. his regiment was in place, and launched its attack. This regiment fulfilled their role with such success that 14 members were awarded the Pour le Mérite.