In 2015, Axelsen finished runners-up at the Swiss Open Grand Prix Gold, three Super Series events India Open, Australian Open, and Japan Open. He qualified to compete at the Super Series Finals held in Dubai, and again finished as the runner-up. Axelsen featured in Denmark winning team at the European Mixed Team Championships in Leuven, Belgium. At the Sudirman Cup, the team finished in the quarter finals lost 2–3 to Japanese team, where he played in the second matches. He ended the 2015 season ranked as world number 6.