The St. Louis Cardinals 2005 season was the team's 124th season in St. Louis, Missouri and the 114th season in the National League. The Cardinals went 100-62 during the season and won the National League Central division by 11 games over the NL Wild-Card Champion and eventual NL Champion Houston Astros. In the playoffs the Cardinals swept the San Diego Padres 3 games to 0 in the NLDS. However, the Cardinals lost to the Astros 4 games to 2 in the NLCS.