Martino was chosen to replace Tito Vilanova as manager of FC Barcelona at the start of the 2013–14 season, but announced his resignation on 17 May 2014, though his side finished runner-up in both the Copa del Rey and La Liga that season. In 2015, he led Argentina to the Copa América Final, only to be defeated by hosts Chile on penalties. His team also finished as runners-up in the Copa América Centenario, again losing to the defending champion Chile on penalties. On 5 July 2016, Martino resigned from the Argentine national team.