His brothers are Aaron Twerski, the Irwin and Jill Cohen Professor of Law at Brooklyn Law School, as well as a former Dean and Professor of tort Law at Hofstra University Law School; Rabbi Michel Twerski, the Hornosteipler Rebbe of Milwaukee; the late Shloime Twerski, the previous Hornosteipler Rebbe of Denver; and the late Mordechai Dov Ber Twerski of New York. Rabbi Abraham Joshua Twerski died in Jerusalem on January 31, 2021 of COVID-19 during the COVID-19 pandemic in Israel. He is survived by his wife Dr. Gail Twerski, three sons, one daughter, grandchildren, great-grandchildren, and great-great grandchildren.