At the age of 24, Alboreto made his Formula One debut at the 1981 San Marino Grand Prix for the Cosworth-powered Tyrrell Racing team, replacing Ricardo Zunino after the Argentine failed to impress team boss Ken Tyrrell. Unfortunately for the Italian, a collision with fellow countryman Beppe Gabbiani put him out of the race after completing 31 of the 60 laps. Alboreto failed to score a single point during his debut year, his highest position being ninth at the Dutch Grand Prix.