On 30 April 2018, Irrati was selected by FIFA as one of the video assistant referees for the 2018 FIFA World Cup in Russia, the first FIFA World Cup to use the technology. Irrati was appointed as VAR in his first World Cup match between Russia and Saudi Arabia on 14 June 2018 in Group A, the opening match of the tournament. On 12 July 2018, Irrati was appointed as the VAR for the 2018 FIFA World Cup Final between France and Croatia. In total, Irrati was the main VAR for 14 matches during the tournament, the most of any official.