On 5 November 2017, Neville became the first woman to referee a Welsh Premier Division match when she took charge of a fixture between Pontypridd and Ebbw Vale. On 15 December 2017 Neville became the first woman to referee a European Rugby Challenge Cup match when she took charge of a 2017–18 pool stage fixture between Bordeaux-Bègles and Enisei-STM. This also saw Neville become the first women to referee a professional European rugby union match. In November 2017, Neville became only the second woman to win World Rugby Referee of the Year, after Alhambra Nievas, who won in 2016. On 9 February 2018 Neville became the first woman to referee a Pro14 match when she took charge of a 2017–18 fixture between Ulster and Southern Kings. This also saw Neville become the first women to referee a top-level men's rugby union match in the United Kingdom.