Hamdi Nagguez has joined to the Tunisian national team in 2015 during the 2017 Africa Cup of Nations qualification. His international debut was against Liberia on 5 September 2015 when they lost (0–1). He was also decisive in the finals of the African Cup after an assist to Taha Yassine Khenissi against Zimbabwe. He was seriously injured and put him out of action for a long time, forcing him to absent from the match Egypt in 2019 Africa Cup of Nations qualification, but returned in the matches of the DR Cogo and Guinea in 2018 FIFA World Cup qualification.