Peranius and his family fled the Sassanid oppression of Iberia into Lazica in the 520s. They placed themselves under Roman protection and left for Constantinople where Peranius joined the Byzantine imperial army. Later in the 530s, he served under Belisarius in Italy and was in Rome during the siege by the Goths (537–538). During the siege, he defended the Porta Praenestina and led a sally from the Porta Salaria. In mid-538, he laid a siege to Urbs Vetus (Orvieto) which fell in early 539.