During the 2010–11 season, she won silver at 2010 Skate Canada International, her first medal on the senior Grand Prix series and placed seventh at the 2010 Rostelecom Cup. At the 2011 Russian Championships, Makarova placed first in the short program and sixth in the free skate, finishing fifth overall. In January 2011, she changed coaches to Evgeni Rukavicin in Saint Petersburg, Russia. Makarova placed fourth at the 2011 European Championships. She finished seventh at Worlds.