In the plague year of 1665 Doolittle and his pupils moved to Woodford Bridge, near Chigwell, close to Epping Forest, Vincent remaining behind. Returning to London in 1666, Doolittle was one of the nonconformist ministers who, in defiance of the law, erected preaching-places when churches were lying in ruins after the Great Fire. His first meeting-house (probably a wooden structure) was in Bunhill Fields, and here he was undisturbed. But when he transferred his congregation to a large and substantial building which he had erected in Mugwell (now Monkwell) Street, the authorities set the law in motion against him.