Lukonina debuted in senior at the 2010 Season, she competed at the 2010 Montreal World Cup finishing 10th in all-around and won silver in ribbon finals. Lukonina finished 6th in all-around at the 2010 St. Petersburg World Cup. She then won the all-around bronze medal at the 2010 Russian Championships. She won silver in ribbon and finished 4th in ribbon finals at the 2010 Corbeil-Essonnes World Cup and finished 10th in the all-around at the 2010 Pesaro World Cup. Lukonina was selected as part of the Russian Team for the 2010 World Championships held in Moscow where she won the gold medal in the team event (together with Evgenia Kanaeva, Daria Kondakova and Daria Dmitrieva).