Basilio José Segundo Pica Valdés (10 July 1892 – 26 January 1970) was a Spanish Filipino doctor, general and minister. Valdes was chief of staff of the Armed Forces of the Commonwealth of the Philippines from 1939, and was in 1941 appointed Secretary of National Defense by President Manuel L. Quezon. After the Japanese invasion of the Philippines at the beginning of the Second World War, he was one of the members of Quezon's war cabinet in exile.