From the reign of Nero onwards, who is said by Tacitus to have blamed the Great Fire of Rome on Christians, the practice of Christianity was criminalized and Christians were frequently persecuted, but the persecution differed from region to region. Comparably, Judaism suffered setbacks due to the Jewish-Roman wars, and these setbacks are remembered in the legacy of the Ten Martyrs. Robin Lane Fox traces the origin of much of the later hostility to this early period of persecution, when the Roman authorities commonly tested the faith of suspected Christians by forcing them to pay homage to the deified emperor. Jews were exempt from this requirement as long as they paid the Fiscus Judaicus, and Christians (many or mostly of Jewish origin) would say that they were Jewish but refused to pay the tax. This had to be confirmed by the local Jewish authorities, who were likely to refuse to accept the Christians as fellow Jews, often leading to their execution. The Birkat haMinim was often brought forward as support for this charge that the Jews were responsible for the Persecution of Christians in the Roman Empire. In the 3rd century systematic persecution of Christians began and lasted until Constantine's conversion to Christianity. In 390 Theodosius I made Christianity the state church of the Roman Empire. While pagan cults and Manichaeism were suppressed, Judaism retained its legal status as a licit religion, though anti-Jewish violence still occurred. In the 5th century, some legal measures worsened the status of the Jews in the Roman Empire (now more properly called the Byzantine Empire since relocating to Constantinople).