In the first round at the 2013 Wimbledon Championships on 24 June, Darcis defeated fifth-seeded Rafael Nadal in straight sets. This made him the first player ever to defeat Nadal in the first round of any major tournament. Darcis was ranked 130 places lower than Nadal. At the time, he was the lowest-ranked player ever to beat Nadal in a Grand Slam tournament. It was announced prior to his second-round match that he had withdrawn due to a shoulder injury sustained in the Nadal match.