In January 2018, it was announced that Patrick would be reunited with longtime partner GoDaddy for sponsorship of the "Danica Double" and assistance as she moved on to her life as a business woman and entrepreneur. For her final NASCAR race at the 2018 Daytona 500, Patrick signed with Premium Motorsports to drive its No. 7 Chevrolet Camaro ZL1 after discussions with Chip Ganassi Racing did not yield in a race seat. Her final Daytona 500 came to an early end when she was involved in a six-car accident on lap 102, placing 35th in the final results. Patrick concluded her NASCAR career with no wins, and finished in the top ten in 3.6% of her 191 races. On March 7, 2018, it was announced that her final Indianapolis 500 appearance would be in a third car for Ed Carpenter Racing.