The Fifth subsequently participated in the offensive campaigns at Aisne, Battle of Saint-Mihiel and in the Meuse-Argonne offensive. They also participated in the defensive campaigns at Toulon-Troyon, Château-Thierry, Marbache and Limey. From 1918 until 1919 the regiment participated in the occupation of the German Rhineland. In August 1919 it relocated back to Marine Corps Base Quantico, Virginia. It was inactivated on August 13, 1919.