Romero was Argentina's starting goalkeeper at the 2014 FIFA World Cup despite lack of first team opportunities whilst at Monaco. In the semi-final, he earned himself Man of the Match by saving kicks from Ron Vlaar and Wesley Sneijder as Argentina defeated the Netherlands 4–2 in a penalty shoot-out to reach the 2014 FIFA World Cup Final on 13 July, where they lost 0–1 to Germany. On 11 July 2014, Romero was named on the three-man shortlist for FIFA's Golden Glove award for the tournament's best goalkeeper due to his performances that led his team to the final.