In her 2016 valedictory speech to the House of Lords before that year's second membership referendum, she described the UK's European Union (EU) membership as "the most central political question that this country has to answer" and said it was the reason for her retirement. In closing, she called on her colleagues to "think very hard before allowing the United Kingdom to withdraw from ... its major duty to the world—the one it will encounter, and then deliver, through the European Union".