On the night of 20/21 April 1941, "Jaguar" formed part of the escort for the battleships , and and the cruiser when they bombarded the port of Tripoli in Libya. On 23 April, "Jaguar" together with sister ships , and set out from Malta to intercept an Italian convoy on the way from Italy to Tripoli. The four destroyers engaged and sunk the Italian armed motor ship south of Lampedusa, but the convoy avoided the searching British ships. "Jaguar" took part in the Battle of Crete, delivering ammunition to British troops fighting on the island and escorting ships carrying out the evacuation from Crete. "Jaguar" was near missed by a bomb on 30 May. In June 1941, Britain launched an invasion of Vichy French Syria and Lebanon, and on 23 June, "Jaguar", together with the cruisers , and the destroyers and , clashed with the , which was hit once but managed to escape.