The 65th Independent Mixed Brigade was an infantry brigade of the Imperial Japanese Army raised during World War II. The brigade was formed as the 65th Brigade in 1941 from a previously existing independent infantry group. It undertook garrison duties on Formosa and then took part in the fighting in the Philippines in 1942. Later, the brigade was dispersed and elements took part in the New Britain campaign. Late in the war, it was converted into an independent mixed brigade to undertake home defense in Japan.