The regiment served two tours in New Guinea. The first began in September 1942 when the regiment supported the 16th Brigade during the final stages of the Kokoda Track campaign, while other elements of the regiment took part in the Battle of Buna–Gona and the defence of Wau. During this time, the regiment expanded existing doctrine for the deployment of artillery by deploying guns into forward areas by air. The regiment returned to Australia for reorganisation in August 1943, and did not see action again until late in the war. It returned to New Guinea in January 1945 to support operations in the Aitape–Wewak campaign, supporting the defence of the airfield around Aitape, the advance on Wewak and operations around Mount Shiburangu. The regiment was in occupation of these areas when the war ended on 15 August 1945. The last of the regiment returned to Australia in January 1946 and was disbanded several weeks later as part of the post war demobilisation.