After Gettysburg, Tilton retained brigade command until August 18, 1863. He returned to regimental command until November 19, when he again resumed brigade command. When the Army of the Potomac was reorganized in 1864 for Lt. Gen. Ulysses S. Grant's Overland Campaign, Tilton was assigned to lead his regiment in Jacob Sweitzer's brigade of Griffin's division. He served in that role in the Battle of the Wilderness, the Battle of Spotsylvania Court House, and the Battle of Cold Harbor, as well as in the early stages of the Siege of Petersburg. Tilton remained in regimental command until June 18, 1864, when he again became acting brigade commander until August 22. During this time he was engaged in action at the battles of Jerusalem Plank Road and Globe Tavern.