Sengbloh has starred in a number of Broadway musicals, including "Aida", "Wicked" (as a standby for Elphaba), "The Color Purple", "Hair", "Fela!", "", and "Holler If Ya Hear Me". Her breakthrough came in 2015, when Danai Gurira cast Sengbloh in "Eclipsed", a play about five Liberian women and their tale of survival near the end of the Second Liberian Civil War. It became the first play with an all-black and female creative cast and team to premiere on Broadway. "Eclipsed" opened Off-Broadway at The Public Theater in October 2015 with positive reviews and ran until November 2015. The following year, it transferred to Broadway, premiering at the John Golden Theatre with an opening on March 6, 2016. Her performance received positive reviews from critics. She won Drama Desk Award for Outstanding Featured Actress in a Play for original Off-Broadway production, and Tony Award for Best Featured Actress in a Play nomination for Broadway production.