On the international stage, Putellas had success with Spain's youth national teams, winning two UEFA Women's U-17 Euros in 2010 and 2011 as well as finishing second place in the 2012 UEFA Women's U-19 Euro. She made her debut for Spain's senior national team in 2012, and has since featured in 3 major international competitions with the team- Spain's Women's World Cup debut in 2015, the 2017 UEFA Women's Euro, and the 2019 FIFA Women's World Cup.