The Cardinals faced the Dodgers in the NL Championship Series (NLCS), and Worrell pitched in four of the six games of the series, making scoreless appearances in Games 1, 3, and 5. Relieving Joaquin Andujar to begin the seventh inning of Game 6, with the score tied at four, Worrell threw a scoreless seventh inning, then gave up a home run to Mike Marshall to start the eighth. He retired the next three hitters he faced, then got the win after Jack Clark hit a three-run home run in the ninth, helping the Cardinals defeat the Dodgers 7–5 and win the series in six games. In Game 1 of the World Series against the Kansas City Royals, Worrell relieved John Tudor with two outs in the seventh and runners on first and third. After walking Lonnie Smith, Worrell got Willie Wilson to pop out to end the inning. In the eighth, he nearly gave up a home run to George Brett, but Andy Van Slyke caught the ball at the fence, and Worrell earned the save as the Cardinals won 3–1.