Harris has publicly shared her experiences with depression, aggression, and Adderall addiction as a youth and young adult, and is heavily involved with the mental health-focused non-profit To Write Love on Her Arms. In May 2016, Harris spoke out in support of Aniya Wolf, a teenager from Pennsylvania who had been barred from her Catholic high school's prom after planning to wear a suit. A Central Florida native, Harris has on a number of occasions expressed support for the victims, families, and communities affected by the June 2016 massacre at the Pulse bar in Orlando. Like many of her U.S. women's national team teammates, Harris has spoken of the sexism faced by female athletes and the importance of improving their pay and conditions.