Pope served as chairman of the Italian Division of the Democratic National Committee in 1936, and helped persuade the president to take a neutral attitude over Italy's invasion of Ethiopia. He broke with Benito Mussolini in 1941 and enthusiastically supported the American war effort. In the late 1940s, Pope supported and helped secure the vote for William O'Dwyer as New York City mayor in 1945 and Harry S. Truman as president. His business concerns continued to prosper under New York's Democratic administrations. In the early years of the Cold War, Pope was a leading anti-Communist, orchestrating a letter writing campaign by his subscribers to stop the Communists from winning the Italian elections in 1948.