Sophie Spence (born 26 February 1987) is a former Ireland women's rugby union international. Spence represented Ireland at the 2014 and 2017 Women's Rugby World Cups. Spence was a member of the first Ireland teams to defeat and . She was also a member of the Ireland teams that won the 2013 and 2015 Women's Six Nations Championships. Spence is a British Nigerian who qualified to represent Ireland through her mother, who was originally from Lisburn, County Antrim.