Following his breakout 2006–07 season, both Udinese and Sampdoria were unable to comes to terms on his co-ownership deal and went to a blind auction on 21 June 2007. In the auction, Sampdoria bid €6.5 million, but were outbid by Udinese, who paid €7.15 million. At Udinese, he started the 2007–08 season slowly, scoring just once in the season's first 11 games. However, he soon found his footing at the club, forming a dangerous strike partnership with Antonio Di Natale and scoring a total of 12 goals in the 2007–08 season. This led to Quagliarella securing a place in the Italian squad for the UEFA Euro 2008 competition. Fabio continued his goal scoring at Udinese in the 2008–09 season, reaching 21 goals in all competitions, including eight goals in the UEFA Cup, where Udinese reached the quarter-finals.