The regiment was reorganized about April 1, 1863, and became part of General Sherman's command. It participated in the movements of that division during the Vicksburg Campaign, though it was in reserve at the May 22 assault. After Vicksburg surrendered, the regiment was engaged at Jackson, Mississippi, and was in the skirmish at and capture of Brandon, Mississippi. It went into camp near Bear Creek on July 23 and remained there until October 10. Lieut. Col. Edgington resigned, Maj. Stibbs became a lieutenant colonel and was succeeded as major by Capt. Edward M. Van Duzee.