Although the 64th Foot fought in many of the major conflicts of the late 18th and early 19th centuries, it was normally in the more minor theatres of these conflicts. During the Seven Years' War it served in the West Indies; in the Napoleonic Wars, its role was limited, again, to the West Indies and South America. In the mid-19th century, it fought in the Anglo-Persian War and the Indian Rebellion of 1857, where one of its soldiers was awarded the Victoria Cross.