Reactivated by Tactical Air Command, United States Air Force on 19 November 1956, being assigned to the reactivated 354th Fighter-Day Group at the new Myrtle Beach Air Force Base, South Carolina. Equipped with North American F-100 Super Sabre fighters, the squadron participated in exercises, operations, tests, and firepower demonstrations conducted by the Tactical Air Command within the US and abroad. The unit frequently deployed to Aviano Air Base, Italy and Wheelus Air Base, Libya. Was deployed to Europe during the 1958 Lebanon crisis and was moved to McCoy Air Force Base, Florida in 1962 during the Cuban Missile Crisis. During the Dominican Civil War, the squadron deployed eighteen of its F-100s to Ramey Air Force Base, Puerto Rico to guard against Cuban intervention in the war.