Comentiolus (, "Komentiolos"; died 602) was a prominent Eastern Roman (Byzantine) general at the close of the 6th century during the reign of Emperor Maurice (). He played a major role in Maurice's Balkan campaigns, and fought also in the East against the Sassanid Persians. Comentiolus was ultimately executed in 602 after the Byzantine army rebelled against Maurice and Emperor Phocas () usurped the throne.