Late in the summer and fall of 1861, there were more than twenty thousand Union soldiers camped to the west of Germantown, in neighboring Darnestown and Poolesville. Occasionally, these soldiers would come to Germantown and frequent the stores there. In September 1862 and in June 1863, several regiments of Union Army soldiers marched north on Maryland Route 355, on their way to the battles of Antietam and Gettysburg, respectively. In July 1864, General Jubal Early led his army of Confederate soldiers down Maryland Route 355 to attack the Union capital of Washington, D.C. Throughout the course of the war, Confederate raiders would often pass through the Germantown area. Local farmers in the Germantown area lost horses and other livestock to both Union and Confederate armies.