Hamels started Game 2 of the 2009 National League Division Series against the Colorado Rockies, allowing four earned runs through five innings to take the loss. Nevertheless, the Phillies won the series, three games to one. He earned the win in Game 1 of the National League Championship Series as the Phillies beat the Dodgers, 8–6. Hamels started Game 3 of the World Series against the New York Yankees, pitching innings, allowing 5 earned runs and taking the loss as the Yankees won that game 8–5. Afterward, he told reporters, "I can't wait for it (the season) to end. It's been mentally draining. It's one of those things where, a year in, you just can't wait for a fresh start", comments that were criticized by manager Charlie Manuel but otherwise largely regarded as speaking out of frustration. Later in the series, after the Phillies won game five, a confrontational Brett Myers mockingly asked Hamels: "What are you doing here? I thought you quit." Years later, in 2018, Hamels joked that Yankee fans love him due to the fact that he helped them win the series. The Phillies lost the series to the New York Yankees in six games.