Sedina competed in the Women's World Chess Championship 2001 where she was eliminated by former Women's World Chess Champion Maia Chiburdanidze in round two, the Women's World Chess Championship 2004 where she was eliminated by Elina Danielian in round one, and the Women's World Chess Championship 2008 where she made it to round three but was eliminated by eventual runner-up Hou Yifan in the rapid playoffs.