She was the Principal Investigator (PI) on a series of SpaceHab/Biorack experiments, which examined the regulation of osteoblast (bone cell) growth. These experiments flew on STS-76, in March 1996, STS-81 in January 1997, and STS-84 in May 1997, and studied the root causes of osteoporosis that occurs in astronauts during spaceflight. One experiment resulted in observations of changes in anabolic signal transduction in microgravity. A later collaborator was Dr. Augusto Cogoli of Zürich, Switzerland; one experiment with Dr. Cogoli was lost in the Space Shuttle "Columbia" disaster, and another experiment using technology from Affymetrix and reverse transcription polymerase chain reaction (RT-PCR) examined changes in T-cell gene induction in spaceflight on a joint NASA/ESA International Space Station mission that launched on the Soyuz TMA-9 in 2006.