Freuler made his first Europa League group stage appearance against English side Everton, playing the full 90 minutes in a 3–0 victory over the "Toffees". He had previously played in a second round qualification two-legged tie against Scottish club St Johnstone for Luzern. He opened his scoring account in the 2017–18 season with Atalanta against Fiorentina, scoring an equaliser in the fourth minute of stoppage time on 24 September 2017.