Söyüncü scored his first Premier League goal in Leicester's 11th game of the 2019–20 season on 3 November 2019 against Crystal Palace at Selhurst Park, a 2–0 win. On 11 May 2021, he scored the winning goal for Leicester City in a 2–1 away victory over Manchester United, to be their first win at Old Trafford since 1998.