Tilgner competed for the women's 4 × 400 m relay at the 2008 Summer Olympics in Beijing, along with her teammates Claudia Hoffmann, Florence Ekpo-Umoh, and Sorina Nwachukwu. Running the start-off leg, Tilgner recorded her individual-split time of 53.12 seconds, and the German team went on to an eighth-place finish in the final, for a total time of 3:28.45.