Ahead of the 2007–08 Serie A season, Juventus loaned Lanzafame to Serie B side, A.S. Bari. Lanzafame endured a highly successful loan spell in which he made 37 league appearances, scoring 10 goals. In April 2008, coach Antonio Conte compared him to Cristiano Ronaldo, stating that he has the possibility and potential to reach similar levels in his football and quoting "Lanzafame has improved tactically” to La Gazzetta dello Sport. “He is explosive, he sniffs the goal, and imposes his speed outside the area. If he improves and learns he can become like Cristiano Ronaldo." Lanzafame returned to Turin on 30 June 2008.