Enzo Masiello (born 5 March 1969) is an Italian Paralympic cross-country skier and biathlete who also formerly competed as a long distance runner at the Summer Paralympics. He has competed at the Paralympics in 6 occasions representing Italy both at the Summer Paralympics (1992, 1996 and 2000) and at the Winter Paralympics (2006, 2010 and 2014). Enzo is also the first Italian male athlete to win a medal both at the Summer Paralympics and in the Winter Paralympics. He was a recipient of the Order of Merit of the Italian Republic, which is one of the highest honours to be given in the nation.