"Vampire" was sent back to Greece, where she operated until May, aiding in the Allied reinforcement (Operation Lustre) and evacuation (Operation Demon). She was then deployed back to the Western Desert Campaign, operating as part of the "Tobruk Ferry Service"; ships transporting supplies and reinforcements to the Allied-controlled, besieged town of Tobruk. However, after two trips, the destroyer had to be removed from service because further engine problems were causing the ship to vibrate excessively at speeds over .