Upon his return to Indianapolis, Leslie Ayres began working as an architect and renderer in the area. He received work from his former employers, Pierre &amp; Wright, as well as other prominent Indianapolis architectural firms such as Rubush &amp; Hunter, A. M. Strauss, and Robert Frost Daggett. His renderings were very popular, often made in watercolor and colored pencil; they were used by architects to lend an air of sophistication to their projects, and were used to sell the client on the project. His early drawings depict a wide variety of subjects including: power plants, high schools, monuments, clubs, civic structures, and religious buildings. His professional drawings in the 1930s and 1940s depicted residences, apartment buildings, and churches. During a visit to the Chicago World’s Fair in 1933, Ayres sketched scenes from Belgian Village. In 1948, National Architect magazine described him as “just about the only professional renderer in Indiana.” His most celebrated work was the design for the Wilkinson House in Muncie, Indiana, which he did in the early 1930s. An Art Moderne masterpiece, the house was, and still is, celebrated as one of the best examples of this style of residential architecture in Indiana. Ayres was also an active leader in the Indianapolis Home Show between 1940 and 1947. He designed many of the model homes used in the show during this time. His focus was on small sophisticated homes that did not trade style for square footage.