Now a regular international, Omeruo has represented Nigeria at the 2013 Africa Cup of Nations and the 2013 Confederations Cup in Brazil. Omeruo cemented a place in the starting line-up at the Africa Cup of Nations as it turned into a wonderful tournament for the Super Eagles and they emerged from the tournament victorious. In 2019 he scored his first goal in the Africa Cup of Nations against Guinea. He was a key part of the Super Eagles team that won the bronze medal in 2019.