She was brought up by her aunt Queen Joan III of Navarre, who raised her as a Calvinist. In 1572 she married in a Calvinist ceremony her first cousin, Henri I de Bourbon, prince de Condé, duc d'Enghien. A few months later, after the St. Bartholomew's day massacre, the couple had forcibly been converted to Roman Catholicism and remarried according to Catholic rites. When her husband fled the court and rejoined the Protestant cause, she refused and stayed behind at court remaining a Catholic the rest of her life.