After the World Cup, he played in a 3–0 Home Championship defeat to Scotland. On 26 November 1958, he helped the Welsh to record a 2–2 draw with England at Villa Park by marking Nat Lofthouse out of the game. He would play for Wales a further eleven times, and only two of these games finished as Welsh victories, both against Northern Ireland. The second of these, at Ninian Park on 11 April 1962 for the 1962 British Home Championship, finished 4–0, and it was Charles who scored all four of the goals. This made him one of only four players ever to score four goals in one game for Wales, the other three being John Price (1882), Jack Doughty (1888), and Ian Edwards (1978). Following this he was included in the tour of South America in 1962, where defeats were recorded by Brazil and Mexico, both of whom were warming up for the 1962 FIFA World Cup – Brazil would go on to beat Czechoslovakia in the final. Wales had missed out on the tournament after narrowly losing their qualifying encounter with Spain 3–2 on aggregate, Charles played in both legs, though with Alfredo Di Stéfano in the team Spain were always considered the favourites.