Senderos was an unused substitute when Arsenal won the Community Shield against Manchester United ahead of the 2004–05 season. He made his debut as a starter in a 2–1 win against Manchester City in the third round of the League Cup on 27 October 2004, and played his first Premier League match on 1 January 2005 as an 82nd-minute substitute for the injured Sol Campbell. Profiting from Campbell's injury, Senderos finished his first Premier League season with 13 appearances. Despite Campbell's recovery, Senderos played the 2005 FA Cup Final in his place, and won his first piece of silverware as Arsenal triumphed on penalties after a 0–0 draw with Manchester United.