Just a few months after the opening of the line, Großbeeren station was put into operation on 16 October 1841. Before that, on 29 August, there had been special services there to mark the anniversary of the Battle of Großbeeren. The station opened at the same time as the start of freight operations on the line. In the early years the nearby Ludwigsfelde station, which was opened at the same time as Großbeeren, was served during the day by just one freight train that also carried passengers; it could be used to travel to Berlin in the morning and to return in the afternoon. In 1849, Großbeeren was initially only served in the summer timetable, but soon passenger trains were stopping throughout the year. Initially, the station was called "Großbeeren", although for several decades from the later 1840s the name was written as "Groß-Beeren".