Ozuna was signed by the Marlins as an amateur free agent in 2008. He is a two-time MLB All-Star (2016, 2017), and won both a Gold Glove and a Silver Slugger Award in 2017, his breakout season. That year, he finished fourth in the National League (NL) in batting average (.312), and third in home runs (37) and runs batted in (124). Following the 2017 season, the Marlins traded Ozuna to the St. Louis Cardinals. In 2020 he led the NL in both home runs and RBIs.