Born in Aalborg, Denmark, Lobo Vedel won his first international medal at the European Youth Summer Olympic Festival in 2013 in a time of 48.37 on the 400m distance while also breaking his first national record. He went on to win the gold medal at the 2015 European Junior Championships and later took the bronze medal at the 2017 European U23 Championships respectively. In 2017 Lobo Vedel managed to place 4th at the European Indoor Championships in Belgrade Serbia as well, marking his debut as a senior.