At the 2008 Summer Olympics in Beijing, Mikue Ondo competed again for the second time in the women's 800 metres. She ran in the fourth heat, against six other athletes, including former Olympic champion Maria Mutola of Mozambique. She finished the race in sixth place by twenty seconds behind Grenada's Neisha Bernard-Thomas, with a time of 2:20.69. Mikue Ondo, however, failed to advance into the semi-finals, as she placed thirty-ninth overall, and was ranked farther below three mandatory slots for the next round. She was eventually upgraded to a higher overall position when Croatia's Vanja Perišić had been disqualified for failing the doping test.