For 2000 Guerrero managed to get a one-off race for A.J. Foyt Enterprises in the No. 41 Harrah's Dallara IR00-Oldsmobile Aurora Indy V8. Guerrero was unable to qualify for the race, making it the first time since 1989 that he failed to start the Indianapolis 500. Guerrero later competed in the Belterra Resort Indy 300 at Kentucky Speedway for Team Coulson in the No. 40 Team Coulson G-Force GF01-Oldsmobile Aurora Indy V8. In the race Guerrero started 25th and finished 23rd after retiring after 48 laps due to engine troubles in what would be his final Indy car race. Guerrero finished the season 44th in the championship with 7 points.