Hejduk has been selected to play in three NHL All-Star Games. In the 2000 All-Star Game, he played on the World team in a 9–4 win over North America. He earned a primary assist on Pavol Demitra's third period goal. For the 2001 All-Star Game, he was chosen to replace an injured Jaromír Jágr in the starting line-up, one of the six Avalanche players selected as starters. However, he did not record a point in a 14–12 loss to North America. In 2009, he was selected as the only Av in the All-Star lineup for the year's Game. He recorded one goal and two assists in a 12–11 shootout loss to the Eastern Conference.