There, she began preparations for the upcoming operations at Iwo Jima. "Anthony" and other ships of the invasion force got underway on 27 January 1945 and stopped en route at Eniwetok and Guam. The destroyer was assigned to the screen of transports carrying reserve forces. She conducted shore bombardment and night harassing fire off Iwo Jima until 6 March, when she got underway for the Philippines.