Marrone started in the opening match of the 2012–13 Serie A season against Parma in a 2–0 win, replacing the injured Giorgio Chiellini in an unfamiliar position as centre back but managed to help keep a clean sheet. Throughout the remainder of the 2012–13 Serie A campaign, he was regularly utilized in central defence after that match. For the second season running, Marrone and Juventus finished the campaign as champions of Italy.