On 28 February 1799, Curzon took command of , and took part in a number of captures, including that of the corvette in 1800, accompanying the expedition to Ferrol in the autumn of that year. In June 1801, he was invalided out of the service due to severe ill-health. He did not return to command until 10 June 1807, when he was given the third rate . "Elizabeth" was part of the fleet under Sir Charles Cotton that blockaded Lisbon during the "Anglo-Russian War", escorted the Russians to Portsmouth, and helped cover the evacuation after Corunna. He was sent out to the Brazil station in early 1809 to search for a French fleet supposed to be bound for the River Plate. Having made a junction with the forces there and found no sign of the French, Curzon escorted a homeward-bound convoy and returned in April 1810. He found he had been appointed a Colonel of Marines on 25 October 1809. His last command was of a squadron blockading Cherbourg.