He signed for fellow Premier League side Liverpool in 2016, for a reported fee of £34 million. With Liverpool, Mané helped them reach back-to-back UEFA Champions League Finals in 2018 and 2019, winning the latter. He also finished as the league's joint-top goalscorer in the 2018–19 season, winning the Premier League Golden Boot. Mané then helped end Liverpool's 30 year league title drought by winning the 2019–20 Premier League.