Ejike began training as a powerlifter shortly before the 2000 Summer Paralympics in Sydney, Australia. At the Sydney Games she competed in the 44 kg weight class taking the silver medal with a lift of 102.5 kg, behind Fatma Omar of Egypt. Four years later at the Athens Games, while competing at the same weight class, she broke the Paralympic powerlifting world record twice on the way to winning the gold medal with a lift of 127.5 kg.