Mikaili Charlemagne (born 1 April 2003) is a Saint Lucian swimmer. Charlemagne represented her country at the 2020 Tokyo Olympic Games in the women's 50 metre freestyle event. She competed in the women's 100 metre freestyle event at the 2017 World Aquatics Championships. In 2019, she represented Saint Lucia at the 2019 World Aquatics Championships held in Gwangju, South Korea. She competed in the women's 50 metre butterfly and women's 100 metre freestyle events.