Regions originally included in Ernest Coe's vision for a national park were slowly added over the years to the park or incorporated into other protected areas: Biscayne National Park, Big Cypress National Preserve, John Pennekamp Coral Reef State Park on Key Largo, Ten Thousand Islands National Wildlife Refuge, and Florida Keys National Marine Sanctuary were all protected after the park's opening in 1947. Everglades National Park was designated an International Biosphere Reserve on October 26, 1976. On November 10, 1978, most of the park was declared a wilderness area. Wilderness designations covered in 2015—about 86 percent of the park. It was listed as a UNESCO World Heritage Site on October 24, 1979, and as a Wetland of International Importance on June 4, 1987. It was placed on the List of World Heritage in Danger from 1993 until 2007 and then again in 2010. The park was added again due to the continued degradation of the set causing significant indications of eutrophication (for example algal blooms) negatively impacting the marine life causing the US government to request UNESCO and IUCN for assistance in development.