A rugged and mountainous region, Epirus was the north-west area of ancient Greece. It was inhabited by the Greek tribes of the Chaonians, Molossians, and Thesprotians. It was home to the sanctuary of Dodona, the oldest oracle in ancient Greece, and the second most prestigious after Delphi. Unified into a single state in 370 BC by the Aeacidae dynasty, Epirus achieved fame during the reign of Pyrrhus of Epirus who fought the Roman Republic in a series of campaigns. Epirus subsequently became part of the Roman Republic along with the rest of Greece in 146 BC, which was followed by the Roman Empire and Eastern Roman Empire.