The "Caimacam" was survived by all his four children. Ion remained especially prominent as a minister of the United Principalities, and from 1863 one of Cuza's leading conservative opponents; his youngest brother, Adolf Cantacuzino (married to Ecaterina Iarca), was the very first President of the Court of Appeals. Having returned to Bucharest, Maria Mavros was noted for her philanthropic work during the Romanian War of Independence. In 1857, Constantin and Zoe's only daughter, Alexandra or Alexandrina, had married General Gheorghe Manu, who later became Prime Minister of the Romanian Kingdom. She died in 1916. While Ion and Maria Cantacuzino had nine children together, Grigore died a celibate in 1903. Of the "Caimacam"s granddaughters, sisters Zoe and Sevastia became wives of two other Prime Ministers: the former married Dimitrie Sturdza, the latter Petre P. Carp. Also a Prime Minister, Gheorghe Grigore Cantacuzino was Constantin's nephew. Other descendants of the "Caimacam" included two famous grandsons: microbiologist Ioan Cantacuzino, born to Maria Mavros, and Adolf's son, the poet and diplomat Scarlat (Charles-Adolphe) Cantacuzino. During their lifetime, their grandfather's image in culture had been codified as negative, with literary historian Gheorghe Bogdan-Duică referring to the "Caimacam" as "one of the most undeserving boyars this country ever had". Constantin was also portrayed as an antagonist in Camil Petrescu's historical novel, "Un om între oameni".