She entered the 2020 24 Hours of Daytona (part of the WeatherTech SportsCar Championship) alongside Rahel Frey, Katherine Legge and Christina Nielsen in the No. 19 GEAR Racing Lamborghini Huracán GT3 Evo. Calderón prepared for the race by increasing her fitness regime and sleeping less in case she was told to drive early in the morning. Multiple car issues relegated the team to a 16th-place finish in class. She shared a Le Mans Prototype 2 (LMP2) Oreca 07-Gibson car in the European Le Mans Series with Sophia Flörsch on the all-female Signatech-run Richard Mille Racing team in 2020. Calderón finished the ELMS season with three top-tens for 11th in the Drivers' Championship with 19 points and was 23rd in the Super Formula Championship with zero points. In September, she made her 24 Hours of Le Mans debut alongside Flörsch and Beitske Visser, finishing ninth in LMP2 and 13th overall.