Following a west coast overhaul, "Wilson" was back off Guadalcanal in January 1943, in time for the last weeks of the fighting there. She subsequently participated in landings on the Russell Islands, bombarded enemy positions on New Georgia and escorted shipping in and around the Solomon Islands. In November 1943, the destroyer screened U.S. aircraft carriers during strikes on Rabaul and Nauru and was similarly employed during attacks on the Marshall and Caroline Islands in January and February 1944.