Chios returned to Byzantine control where it remained until 1346, when the Genoese Simone Vignose captured it, taking advantage of the Byzantine civil war of 1341–1347. The island became the seat of the "Maona di Chio e di Focea" company, and fell under the rule of the Giustiniani family, who held it until 1566, when it finally capitulated to the Ottoman Empire.