At the 2010 Wuxi Classic, Ding lost 8–9 in the final despite leading 8–2. Ding reached the second round of the Shanghai Masters and the quarter-finals of the World Open, where he lost 1–5 to Jamie Cope and 2–3 to Mark Williams. Ding failed to defend his 2010 UK Championship title, losing 8–9 against Mark Allen. In January 2011, Ding reached his second Masters final, beating Jamie Cope 6–3 in the semi-final. Ding won the Masters for the first time, beating Marco Fu 10–4 in the first-ever all-Chinese Masters final.