In January 2014, de Pablo was announced to have been cast in the film "The 33", about the 2010 Copiapó mining accident, as the wife of one of the miners. She was also cast in the 2015 CBS miniseries "The Dovekeepers", based on the Alice Hoffman novel. In March 2016, "Deadline Hollywood" reported de Pablo is slated to return to series television as Laura Kale in Syfy's thriller-drama, "Prototype", pending negotiations. In April 2016, TVLine columnist Matt Mitovich confirmed de Pablo's return to series television. The show was to feature "three unlikely colleagues—two of them played by de Pablo and Jack Davenport—who inadvertently stumble upon an invention that challenges the very nature of quantum physics—a discovery which in turn puts their lives in grave danger." In August 2016, "Deadline" reported that Syfy passed on the show.