Population at the beginning of the second half of the 17th century, is estimated in about 2,000 families, approximately 10,000 persons. When the Calchaquí Wars ended survived about 2,000 people (1665), which were taken prisoners and deported to a reservation located near Buenos Aires. But to the reservation just arrived only 200 families (about 1,000 people). In 1726, there were 141 people. William Beresford found a ghost town when he visited the reservation during the first British invasion of the River Plate in 1806. According to the last parish priest of the reserve, the last natives died in the late 18th century. The population was decimated by the high rate of infant mortality and epidemics. The government officially declared the ethnic group extinct on February 12, 1812 (but admitting that there are mestizo families) and the reservation was finally closed on August 14, 1812.