Massive areas of land were cleared for agriculture and various other purposes in the first 100 years of European settlement. In addition to the obvious impacts this early clearing of land and importation of hard-hoofed animals had on the ecology of particular regions, it severely affected indigenous Australians, by reducing the resources they relied on for food, shelter and other essentials. This progressively forced them into smaller areas and reduced their numbers as the majority died of newly introduced diseases and lack of resources. Indigenous resistance against the settlers was widespread, and prolonged fighting between 1788 and the 1920s led to the deaths of at least 20,000 indigenous people and between 2,000 and 2,500 Europeans.