Sicari began 2008 with a win at the Maratonina dei Tre Comuni, followed by a second-place finish at the Rome-Ostia Half Marathon in a personal best of 1:10:21 hours. An attempt to gain an Olympic place at the Rome City Marathon failed after she dropped out of the race. She rebounded with a win at the La Lagarina half marathon later that month and just dipped under FIDAL's time standard of two hours thirty minutes at the Turin Marathon, gaining selection and the women's title in a personal best of 2:29:51 hours. She won the women's race at the Trofeo San Vittore in June. On her debut Olympic appearance at the 2008 Beijing Olympics Marathon she came 29th with a time of 2:33:31 hours. She brought her year to a close with a third-place finish at the Turin Half Marathon and a win at the Straconi Golden Run in Cuneo.