On 2 January 2013, Henríquez joined Wigan Athletic on loan until the end of the 2012–13 season. It was confirmed he could wear the number 11 shirt. He made his debut in English football as a half-time substitute for Daniel Redmond in an FA Cup third-round game against Bournemouth on 5 January, a 1–1 draw at the DW Stadium. His Premier League debut came two weeks later as a 71st-minute substitute for Emmerson Boyce against Sunderland, and eight minutes later he headed in Shaun Maloney's cross for Wigan's second goal in a 3–2 home loss. He won his first major trophy on 11 May 2013, as an unused substitute in the 1–0 FA Cup Final win against favourites Manchester City.