In January 1942, "Yūgure" escorted aircraft carriers and to Palau and to Ambon during the invasion of the Netherlands East Indies, and was a participant in the Darwin air raid of 19 February 1942. Afterwards, she was based at Staring Bay, in Sulawesi from which she conducted escort patrol missions to the end of March. She returned to Sasebo Naval Arsenal for repairs from 22 March to 15 April 1942. At the end of April, she went to Truk as part of the escort for the aircraft carriers and and was part of Admiral Takagi's force at the Battle of the Coral Sea.