Born in Turin, Avogadro debuted in the late 1960s as the vocalist of the short-lived vocal group . After the group disbanded, he started a career as a lyricist, getting his first hits in collaboration with Sandro Giacobbe in the early 1970s. He was a usual collaborator of Mario Lavezzi and Oscar Prudente. In 1983 his song "Margherita non lo sa" ranked third at the 33rd edition of the Sanremo Music Festival.