Sahagian conducted independent research on several Armenian subjects, with particular attention to the work of the American missionaries in Sivas and Van, as well as scholarly articles on the Hamidian Massacres and the Armenian genocide. Her articles were published in the "Journal of Armenian Studies", "Ararat", and the "Armenian Mirror-Spectator" newspaper and in the book Armenian Sebastia/Sivas and Lesser Armenia. She participated in the work of the Sebastasti Compatriotic Union and the Historical Commission of Arlington, Massachusetts.