On 12 December 2016, it was confirmed by festival organizers that Comello would be taking part in the 2017 edition of the Sanremo Music Festival, considered the greatest music festival in Italy. The winner of the festival is offered a chance to represent Italy in Eurovision. She participated with the song, "Il cielo non-mi basta". The Sanremo Music Festival was held from 7 to 11 February 2017. Comello finished in 12th place out of 16 finalists. Directed by her husband, the official music video for "Il cielo non-mi basta", was released on her official VEVO account in Italy on 8 February 2017. The song peaked at 37 on the Italian FIMI Singles Chart, becoming the first single of her music career to enter on the chart. On 5 May 2017, she released her first single, "50 Shades of Colours", from her upcoming third studio album. The music video, filmed in Rome, was premiered as an exclusive for Corriere della Sera, the Milan-based newspaper. Comello performed three concerts in Rome on 19 May, in Milan on 26 May, and in Udine on 21 July to promote her new music.