After the Red Army invasion of Georgia in 1921 she was active in the anti-Bolshevik movement, but was exiled to Moscow in 1924 after an uprising in Georgia. Arrested again in the 1930s, her husband and two sons were shot while she was exiled to the Kazakh SSR. Released from detainment in 1950, she returned to Georgia, and was rehabilitated in 1956. Orjonikidze died in 1967. Her cousin was Sergo Ordzhonikidze, who would become a prominent Bolshevik and close ally of Joseph Stalin.