Mehmed Siroco was appointed admiral in command of the Turkish right at the Battle of Lepanto (1571). Fighting the "Lega Santa" led by Admiral Agostino Barbarigo, he was known as the most aggressive attacker of the battle. He was wounded and killed in action when he struggled against Venetians at the Battle of Lepanto, as was Barbarigo. Mehmed Siroco was beheaded by the sword of Giovanni Contarini the Venetian.