He was the double Pan American champion and the NCAA champion in the 100 m and 200 m. De Grasse won the bronze in the 100 m and the 4 × 100 m relay at the 2015 World Athletics Championships in Beijing. He also won the bronze in the 100 m and the silver in the 200 m at the 2019 World Athletics Championships in Doha. He is the current Canadian record holder in the 200m, running a 19.62 in Tokyo, making him the eighth fastest man in history in the 200.