Amphipolis, an Athenian colony, was the seat of the battle between the Spartans and Athenians in 422 BC, and also the place where Alexander the Great prepared for campaigns leading to his invasion of Asia. Alexander's three finest admirals, Nearchus, Androsthenes and Laomedon, resided in Amphipolis, which is also the place where, after Alexander's death, his wife Roxana and their son Alexander IV were exiled and later murdered.