Mazzola retired from professional football in the summer of 1977, having served as Inter's captain from 1970 until his retirement. By the end of his career, he had won four Serie A titles (1963, 1965, 1966 and 1971), two European Cups (1964 and 1965), two Intercontinental Cups (1964 and 1965), one European Championship (1968) and was top scorer during the 1964–65 Serie A season.