Advanced for the first in time in 1959 by eminent Israeli specialist in tropical medicine Dr. Saul Adler from Hebrew University, the hypothesis of Chagas disease was based partly on the fact that during the "Beagle" expedition, Darwin was bitten by the insect vector of this disease near Mendoza to the east of the Argentinian Andes while on one of his land exploration trips. He noted in his journal for 26 March 1835: