Gentile responded to other aspects of the East, including the Byzantine Greek Empire, as well as Venice's other trading partners in North Africa and Levant. Venice had a long-established relationship with the Eastern Mediterranean. Saint Mark, Venice's patron, was from the Egyptian city of Alexandria, and Venice's cultural and spiritual centre – the basilica of San Marco – was built in his honor (and as his mausoleum) in the Greek Byzantine style. Although Constantinople fell to the Ottoman Turks in 1453, the Greek Byzantine world had a continuing impact upon Venetian art and culture as a number of Greek Christians fled Muslim rule. It was here that Gentile painted the portrait of Queen Caterina Cornaro of Cyprus (at right). This is counted as the second known portrait including the queen, which is now in the collection of the Szepmuveszeti Museum in Budapest.