As the winner of the FIDE Women's Grand Prix 2011–2012, Hou won the right to challenge Anna Ushenina in a 10-game match for the world title. Scheduled from September 10 to the 27th, the Women's World Chess Championship 2013 was played in Taizhou, Jiangsu, China. She won the match in 7 games with a 5.5–1.5 score (+4 =3, TPR 2730) regaining her championship title.