She resigned the Ministry of Education in October 4, 2016, shortly after the referendum of the Colombian peace process was voted as "No". It is believed it had to do with sex-ed schoolbooks called "Ambientes Escolares Libres de Discriminación" (Discrimination-Free School Environments) that were accused of promoting homosexuality and gender ideology. Former president Álvaro Uribe and former Inspector General Alejandro Ordóñez joined the campaign against said schoolbooks.