Vos started the year with a 3rd place in the cyclo-cross world championships. She then switched to mountain biking, with an eye on participating in that discipline in the Rio Olympics. She won her first race, but broke a rib preparing for a race in Austria. The rest of her 2015 season was plagued by a persisting hamstring injury. She later announced she was overtrained and would not participate in the 2015–2016 cyclo-cross season.