St. Mary's Catholic Church is a parish of the Roman Catholic Church located near Bryantown, Maryland, in the Archdiocese of Baltimore. Established in 1793, it operates a parochial school and houses a large cemetery. St. Mary's Cemetery is most notably the final resting spot of Dr. Samuel Mudd, a physician who set the leg of John Wilkes Booth the day after U.S. President Lincoln's assassination on April 14, 1865. As such, it is a stop on the Booth's Escape Scenic Byway.