Pagenaud won the Grand Prix of Indianapolis and he would also win the 2019 Indianapolis 500 from pole position. Pagenaud took the championship lead from Team Penske team mate Josef Newgarden, however Newgarden would retake the championship lead one race later in Detroit. Pagenaud would take pole and the win at the 2019 Honda Indy Toronto and took pole at the 2019 Iowa 300, though the win would go to Newgarden.