Karekin Khajag was one of the Armenian leaders deported during the Armenian Genocide. On the night of 24 April 1915, Khajag was arrested and imprisoned in Constantinople, then sent via train to Ayaş, a village located in the interior provinces of the Ottoman Empire. Confined in a prison at Ayaş, Khajag along with Rupen Zartarian, Sarkis Minassian, Khachatur Malumian, Harutiun Jangülian, and Nazaret Daghavarian were to be transferred to Diyarbakir on 2 June. Ostensibly, they were to undergo a court-martial in Diyarbakir; however, Khajag along with the rest were murdered en route in the area of Karacur between Urfa and Severek (today Siverek). The order for the murder was given from Captain Şevket to Haci Onbaşı, a member of the Special Organization.