The brigade's most notable action was in the Battle of El Alamein from 23 October to 4 November 1942. For the battle, the brigade was attached to 10th Armoured Division and equipped with 2 Grants, 93 Shermans and 45 Crusaders for a total of 140 tanks. On the night of 24/25 October, the brigade took part in the unsuccessful thrust by 10th Armoured Division from Miteirya Ridge. The leading unit, 8th Armoured Brigade, was caught on their start line at 22:00 – zero hour – by an air attack and were scattered. 24th Armoured Brigade had pushed forward and reported at dawn they were on the "Pierson" line, although it turned out that, in the dust and confusion, they had mistaken their position and were well short. On 27 October, the brigade supported the 2nd Battalion, Rifle Brigade's attack on "Outpost Snipe". The brigade was soon in contact with the Rifle Brigade (having shelled them in error for a while). Some hours of confused fighting ensued involving tanks from the Littorio Armoured Division and troops and anti-tank guns from 15th Panzer Division which managed to keep the British armour at bay in spite of the support of the Rifle Brigade battlegroup's anti-tank guns.