Wood scored his first senior international goal in June 2015, a game-winner in a 4–3 victory against the Netherlands. Five days later, Wood scored the game-winning goal in a 2–1 friendly victory against top-ranked Germany in Cologne. In the 2015 CONCACAF Cup against Mexico to decide which team would qualify for the 2017 Confederations Cup, coach Jürgen Klinsmann substituted Wood on in the 98th minute, after Mexico scored the go-ahead goal in extra time. Wood scored the tying goal in the 108th minute on a through ball from DeAndre Yedlin, but the United States ended up losing the match on an additional extra time goal from Mexico. On September 5, 2017 Wood scored the tying goal in the 85th minute against Honduras to keep the US hopes alive in the CONCACAF qualifications for the 2018 FIFA World Cup in Russia, securing a 1–1 draw. On October 6, he scored a goal to give a 4–0 lead for United States against Panama with one more match in the group to spare.