At the 2010–11 Grand Prix Final, Czisny won the short program with 63.76 points and placed third in the long program with a new personal best of 116.99 points. She won her first Grand Prix Final title with a new personal best combined total of 180.75 points. At the 2011 U.S. Championships, Czisny placed second in the short program with 62.50, and then placed first in the free skate with 128.74, giving her a combined total of 191.24 to win the gold. She thus won her second national gold medal, finishing 7.86 points ahead of the defending champion Rachael Flatt. It was the first time since Michelle Kwan's ninth win in 2005 that a ladies' single skater won more than one U.S. national title. She placed fifth at the 2011 World Championships, her best ever result at the event. During the off-season, she skated in a number of shows. In 2011, she also made a brief appearance in a Super Bowl commercial for Chrysler and Detroit and starred in Chrysler's "Perseverance" video.