Knox's regiment participated in the New York and New Jersey Campaign during the summer and fall of 1776. The actions in which cannons were employed were the battles of Long Island, White Plains, and Fort Washington. Elements of the regiment also defended Lake Champlain. Knox's guns were crucial in winning the Battle of Trenton in late December 1776. The regiment was disbanded on 1 January 1777 and replaced by four newly raised artillery regiments.