After the death of Pope Urban VIII, newly elected Pamphili Pope Innocent X launched an investigation into the Barberini's handling of funds during the Wars of Castro. Colonna's husband, Taddeo, and his brothers, cardinals Francesco Barberini and Antonio Barberini went into exile in Paris with the support of Cardinal Jules Mazarin. Mazarin was the uncle of Marie Mancini; wife of Colonna's nephew Lorenzo Onofrio Colonna and a confidant of Colonna's brother, Cardinal Girolamo Colonna. Mazarin had also served as infantry captain under Colonna's father, Filippo Colonna.