Zetlin placed 23rd all-around (99.025) at the 2010 World Rhythmic Gymnastics Championships in Moscow, Russia, where she became the first U.S gymnast to advance to the world all-around finals since Mary Sanders in 2003. At the 2010 Pan American Games in Guadalajara, Mexico, Zetlin won the all-around, rope and ball, and she placed third in ribbon. The U.S. also earned the team silver medal in rhythmic gymnastics.