After the demise of Setanta, it was announced in July 2009, that she had joined ESPN's new UK sports channel, to co-host their new Premier League football coverage, alongside Ray Stubbs, who joined ESPN from the BBC. At ESPN she became the first woman in the UK to host the FA Cup Final, presenting a 7-hour broadcast pitch side from the 2012 FA Cup Final between Chelsea and Liverpool. She was also there for ESPN when the Bolton Wanderers midfielder Fabrice Muamba collapsed on the pitch at White Hart Lane during an FA Cup quarter-final in March 2012. She co-hosted the network's telecasts of the 2011 FIFA Women's World Cup alongside Bob Ley. In January 2011, she hosted the FA Cup third round game between Arsenal and Leeds United with Robbie Savage and Martin Keown. At half time Savage was showered with hot dogs and coins by Leeds fans. In June 2012 she appeared on US television as co-host of ESPN's US coverage of UEFA Euro 2012. Lowe also sporadically presented ESPN USA's Premier League coverage.