Between 1841 and 1846 "Pique" served on the North America and West Indies Station. With HMS "Blake", in 1845 she acted as a cable ship for experiments in laying telegraph cable in Portsmouth Harbour. From 26 December 1853 she was commanded by Captain Frederick Nicolson on the Pacific Station, and participated in the 1854 Anglo-French squadron sent to the Russian War and Second Anglo-Chinese War). She was present at the Siege of Petropavlovsk.