Reverting to its original mounted infantry role, the regiment saw service in the Middle East for the remainder of the war, taking part in numerous actions including those at Romani and Beersheba. The regiment was later given the honour of leading the Australian Mounted Division, and accepted the formal surrender of the city of Damascus on 1 October 1918. Later, while awaiting repatriation, the regiment was used to suppress a nationalist uprising in Egypt in 1919. Following its return to Australia, the 10th Light Horse Regiment was disbanded in 1919.