Since joining the Major League umpiring staff in 1999, Welke has worked the Division Series in 2003, 2006, 2011, 2015 and 2020. He also worked the League Championship Series in 2014, 2016, 2017 and 2019 as well as the 2015 World Series. He was a part of the crew that worked in the 2003 Major League Baseball All-Star Game.