He died at the age of 31 after falling ill to a fever. He had at least one son, Hans Buser III (1538-1584), who came to be known as "der Canis" for his bravery and death in the Cologne War in 1584. In addition, he had two other sons, named Mathis and Martin Buser. The Buser family was eventually displaced from Liestal during the Thirty Years' War, and Hans' great-grandson, Georg, moved the family to his maternal homeland in Saxony under the name of Bausser. Most of the family remained there, while others emigrated to Philadelphia in the early 1700s under Matthias Bowser. The town of Addison in Somerset County was mostly home to the Bausser family (which eventually was changed to Bowser), while others moved to Accident, Maryland.