First founded in 1268, the Franciscan monastery at Multyfarnham is still home to a community of friars. During the English conquest of Ireland in the 17th century, the monastery was raided six times and twice burnt out by the Crown forces battling the forces of the 'Irish of Meath'. During the wars of the 1640s, it became an organisational centre for the powerful and influential Franciscan order, who met there in their provincial assembly at the outbreak of the 1641 rebellion. In 1646, there were 30 friars in residence. By the middle of era of the Penal Laws there were as few as seven friars, five of whom were of advanced age. The church was unroofed from 1651 and remained so until 1827. In 1839, a new friary was rebuilt in the grounds.