During the Allied landings at Anzio, Italy, on 22 January, "Le Fantasque" carried out a diversionary bombardment of Civitavecchia and then bombarded Formia and Terracina the following day. In late February the 10th LCD was tasked to conduct deep raids in the Adriatic in search of German shipping. The first two raids on 27–29 February were unsuccessful, but on the night of 29 February/1 March they encountered a heavily escorted cargo ship. "Le Fantasque" and "Le Malin" sank the freighter and heavily damaged the torpedo boat and a corvette in the Battle of Ist. Further sweeps were fruitless although the cruisers bombarded Zante on the night of 7/8 March. On the night of 18/19 March, "Le Fantasque" and "Le Terrible" encountered a German convoy and sank two Siebel ferries and damaged two other ferries. Both cruisers were struck by return fire that wounded eight men aboard "Le Fantasque" and one crewman on "Le Terrible". The ships were refitted and then transferred to Alexandria, Egypt, to conduct patrols south of Crete and in the Aegean in April where they had no engagements other than a bombardment of Kos. Transferred back to the Adriatic in June, "Le Fantasque" and "Le Terrible" sank the small oil tanker on the 17th. During the last raid on the night of 24/25, "Le Fantasque"s port propeller shaft began vibrating which limited her to a speed of . On 15 August, the 10th LCD provided naval gunfire support during Operation Dragoon, the Allied landing in Provence, "Le Fantasque" firing 280 shells from her main guns. Together with "Le Terrible", "Le Fantasque" escorted "Richelieu" to Toulon on 1 October.