Wittenberg turned professional in 2004 and played on the PGA Tour, Web.com Tour (formerly Nationwide Tour), and mini-tours since. In 2012, Wittenberg won his first title on a major golf tour, the Nationwide Tour's Chitimacha Louisiana Open. He followed it up three months later with his second win of the season at the Preferred Health Systems Wichita Open, one week after finishing T10 at the U.S. Open.