"Shoshone" departed Pearl Harbor on 25 January and arrived at Saipan on 11 February. She participated in an invasion rehearsal off Tinian the next day, and departed Saipan on 16 February for the invasion of Iwo Jima. She arrived off Iwo Jima early on 19 February, sent her boats to help offload troops from the attack transports, and discharged small amounts of high priority cargo as called for by the troops ashore. On 26 February, general unloading of cargo began, and "Shoshone" completed unloading on 1 March and departed Iwo Jima the same day.