Aquino has been called up to the Mexico U-23 national team, where he was a part of the squads playing at the 2011 Copa América, the 2011 Pan American Games, and the 2012 Summer Olympics, where Mexico won the gold medal. He made his debut with the senior national team in 2011, and participated in the 2013 and 2017 FIFA Confederations Cup, as well as the 2014 and 2018 FIFA World Cup.