Pepeleva/Pleshkov opened their first fully senior season at the third event of the domestic Russian Cup series in Sochi, the qualifying competition series to the 2021 Russian Figure Skating Championships. They placed third in both the short program and the free skate to finish third overall behind teammates Daria Pavliuchenko / Denis Khodykin and Iuliia Artemeva / Mikhail Nazarychev. At their next event, the fourth stage of the Russian Cup held in Kazan, they placed sixth in both the short and free programs to finish sixth overall.