At the 2017 Prefontaine Classic, Miller-Uibo became the first Bahamian woman to run under 22 seconds in the 200 metres, improving her own national record to 21.91 seconds. On 4 June 2017, she set the 200 metres straight world record of 21.76, greatly improving the previous record of 22.55 set by Allyson Felix. At the 2017 World Championships she won the bronze medal in the 200 metres race. She finished fourth in the 400 metres event. In the same year, Miller-Uibo won both the 400 m and the 200 m Diamond League titles, making her the first Bahamian to ever win a Diamond League title.