Born in Biella, Piedmont region, Beltrame began his youth career with Novara Calcio. He was signed by Juventus F.C. in 2011 in a co-ownership deal, for €750,000, where in the "Primavera" (under-19) squad, with whom he graduated the youth academy in June 2013 after helping the club to several youth-team accolades, including the 2013 Coppa Italia Primavera and the 2012 Torneo di Viareggio. During the 2012–13 Serie A season, Beltrame also began to earn a handful of first-team call-ups by head coach, Antonio Conte. Juventus also signed Beltrame outright for an additional fee of €750,000 (half of the registration rights of Alberto Libertazzi plus €300,000).