Since 2006, he has starred in Progresso commercials, advertising their soup brand. On March 5, 2009, Lithgow made a cameo on NBC's "30 Rock" acting in the episode "Goodbye, My Friend" with several references to his role in "Harry and the Hendersons". In September 2009, Lithgow joined the cast of "Dexter" as Arthur Mitchell, a serial killer and Dexter Morgan's nemesis. He won a Golden Globe Award for this role and won an Emmy for Outstanding Guest Actor In A Drama Series. He guest starred on "How I Met Your Mother" in the role of Barney Stinson's father, Jerry.