Ledbetter played four seasons for the Georgia Bulldogs. After serving a suspension for the first six games of the season stemming from off the field issues, He entered the starting lineup during his sophomore year and finished the season with 24 tackles and a sack in seven games played. As a junior, making 38 tackles (5.5 for loss) with 2.5 sacks in 15 games (11 starts) in Georgia's run to the Playoff National Championship Game. In his senior season, Ledbetter led all Georgia defensive linemen with 56 tackles and finished second on the team with 6.5 tackles for loss with a sack and two forced fumbles and was named second team All-Southeastern Conference by the league's coaches. He finished his collegiate career with 122 total tackles, 14.5 tackles for loss, 4.5 sacks, and 2 forced fumbles. Following the end his final season, Ledbetter received an invitation to play in the 2019 Senior Bowl.