After Wahunsenacawh's death, his younger brother, Opitchapam, briefly became chief, followed by their younger brother Opechancanough. In 1622 (Indian massacre of 1622) and 1644 he attacked the English to force them from Powhatan territories. Both these attempts were met with strong reprisals from the English, ultimately resulting in the near destruction of the tribe. The Second Anglo–Powhatan War that followed the 1644 incident ended in 1646, after Royal Governor of Virginia William Berkeley's forces captured Opechancanough, thought to be between 90 and 100 years old. While a prisoner, Opechancanough was killed, shot in the back by a soldier assigned to guard him. He was succeeded as "Weroance" by Necotowance, and later by Totopotomoi and by his daughter Cockacoeske.