On September 13, the 140th Mixed Brigade was sent to the Ebro front, as a reinforcement of the republican forces in this sector. On September 19 it relieved the 227th Mixed Brigade in the area northwest of La Pobla de Massaluca, the position in which it remained until October 6 - when it was replaced by the XIII International Brigade. Unlike other Republican units, in this period the 140th Mixed Brigade did not participate in heavy fighting. Three days later, on October 9, it had to return to the battle front in the area of Venta de Camposines. On October 15 it had to withstand a strong enemy onslaught, although it maintained its positions at the cost of some casualties — notably the death of the chief of the 560th battalion, Vicente Sagarduy. On November 8, during the last nationalist counteroffensive, the 140th Mixed Brigade was encircled by its company of machine guns and by a company of the 559th Battalion, which resulted in serious casualties. Three days later, due to the withdrawal of the 226th Mixed Brigade, it suffered a new enemy encirclement that caused heavy losses to the unit; severely broken, on the November 13 it crossed the Ebro through the Flix area.