Mauritius sent a delegation to compete at the 2016 Summer Paralympics in Rio de Janeiro, Brazil, from 7–18 September 2016. This was the fifth time the country had taken part in a Paralympic Games after its debut at the 1996 Summer Paralympics. The Mauritian delegation to Rio de Janeiro consisted of two athletes: wheelchair racer Brandy Perrine and short-distance swimmer Scody Victor. The nation's best result was tenth overall by Perrine in the women's 100 metres T54 event as both competitors did not progress to the final in their respective competitions.