After repairs at Philadelphia from August–October 1862, "Wissahickon" joined the blockade of the coasts of South Carolina, Georgia and eastern Florida. She took part in bombardments of Fort McAllister, Georgia, in late 1862-early 1863 and in the destruction of the privateer "Rattlesnake" (ex-CSS "Nashville") on 28 February 1863. One of her sailors, Captain of the Forecastle Henry Shutes, was awarded the Medal of Honor for his part in the action at Fort McAllister and the earlier Battle of Forts Jackson and St. Philip. In March–June 1863, "Wissahickon" destroyed one blockade runner (the SS "Georgiana") and helped to destroy another. During the summer, she bombarded Forts Wagner and Sumter, off Charleston, South Carolina.