In 2006, Lazier returned to Dreyer &amp; Reinbold Racing after practicing for the team at the 2004 Indianapolis 500. Lazier drove the No. 5 Dallara IR03-Honda. Lazier attempted to compete in his first full-time season since 2002. At the season-opening Toyota Indy 300 at Homestead, Lazier started in 14th place. The race weekend was overshadowed by the death of Paul Dana in final practice; Lazier retired after 12 laps due to an electrical problem, and was scored in 14th. Lazier competed in his first non-oval race at the Honda Grand Prix of St. Petersburg. Lazier started in 18th place and was scored in 14th place due to a brake problem after completing 59 laps. At Motegi, Lazier started in 15th place and finished in 14th place, five laps down. At the Indianapolis 500, Lazier qualified in 25th place. Lazier was running in the top 10 in the second half of the race, but had to make a late-race pit stop to have enough fuel to finish the race and he finished in 12th place, one lap down; his best result of the season.