Her first film role was in 1987's "Angel Heart". Her first major role was as Mabel opposite Brad Pitt in Robert Redford's "A River Runs Through It". She had acted with Brad Pitt previously in the film Johnny Suede, the scene was subsequently cut from the film. She portrayed Barbara Soprano on the HBO television series "The Sopranos" from 2000 to 2001. She received the Best Screenplay Award at the 2001 Newport Beach Film Festival for "Maze". She adapted her critically acclaimed play Chelsea Walls into a feature film directed by Ethan Hawke, which premiered at the 2001 Cannes Film Festival.