The knockout stage of the 1999–2000 UEFA Champions League began on 4 April 2000 and ended with the final at the Stade de France in Saint-Denis on 24 May 2000. The top two teams from each of the four groups in the second group stage competed in the knockout stage. For the quarter-finals, each group winner was randomly drawn against the runner-up from another group. The four quarter-final winners were then drawn together for the semi-finals, the winners of which contested the final.