Ferrand-Prévot endured a difficult 2016 season. She competed in the 2016 Summer Olympics in Rio de Janeiro, however she only finished 24th in the road race and abandoned the cross-country mountain bike race due to struggling with the effects of the tibial fracture she had sustained during the winter. She subsequently ended her season after the Games. In September 2016, after five years with the Rabobank team it was announced that Ferrand-Prévot would join for the 2017 season.