This palace is notable for the inhabitants and visitors over the centuries. In 1057, it was occupied by Bellino di Pancio. Attanai returned to this house in 1187 from the second crusade and left for the third in 1219. In 1261, Astancollo, count of Lucciano became head of the Ghibelline faction in Pistoia; but five years later, after the defeat in the Battle of Benevento of the Ghibelline army led by King Manfred of Hohenstaufen, led to a mass expulsion of the fraction from Pistoia, including Vinciguerra. Martino Panciatichi lived here, he is known as the Ghibelline warrior who blocked the re-entry of Fillipo Tedici into Pistoia, slaying and decapitating Tedici at a bridge near San Marcello Piteglio. Putatively a sculpted head on display in the church of Sant'Andrea represents Tedici, who was despised by Pistoians for having betrayed and sold their city to the bellicose leader of Lucca, Castruccio Castracani. Also living in this house was Giovanni Panciatichi, who in 1329 mended the disputes between his family and that of the Cancellieri. Factions led by the latter family burned this palace a number of times during the 15th and 16th centuries.