Macdonald repeatedly ridiculed public figures such as Marion Barry, Bill Clinton, Michael Jackson, and O. J. Simpson. Throughout Simpson's murder trial, Macdonald constantly pilloried the former football star, often heavily implying Simpson was guilty of the brutal slaying of his ex-wife Nicole and her friend Ronald Goldman. In the broadcast following Simpson's acquittal, Macdonald opened "Weekend Update" by saying: "Well, it is finally official: murder is legal in the state of California."