He played his first game back from injury against Arsenal in the FA Cup sixth round on 12 March 2011. On 9 April 2011, he scored his first league goal of the season as he netted the second of a 2–0 home win over Fulham. Days later, he scored the first goal in United's 4–1 victory against the German team Schalke 04 in the second leg of the semi-final of the 2010–11 UEFA Champions League, game in which he was selected as player of the match. He became the first Ecuadorian player to win a Premier League medal, in the 2010–11 season. Valencia was a starter in United's 3–1 defeat to Barcelona in the 2011 Champions League Final at Wembley Stadium.