During the Second English Civil War she was among the ships that were brought over to the royalist side by vice admiral William Batten in June 1648 and carried into Hellevoetsluis in the Netherlands. When Prince Rupert was made commander of the badly equipped royalist fleet, he sold "Antelope"'s brass guns to fit out some other ships. In the spring of 1649 "Antelope" was ready for sea, but her weak crew was surprised by a raid of seamen from the parliamentarian ship "Happy Entrance" who took the ship without a fight and immediately destroyed her.