John Angelos (, ) was a Byzantine aristocrat, general, and governor. He first distinguished himself in the suppression of a revolt in Epirus in 1339–1340, where he was subsequently appointed as governor. A relative of the statesman and emperor John VI Kantakouzenos, he took the latter's side in the Byzantine civil war of 1341–1347 and in late 1342 received the governorship of Thessaly (and possibly Epirus), which he held until his death in 1348.