The brigade left the 2nd Mounted Division on 17 January 1916 and was sent to the Western Frontier of Egypt as an independent formation. On 31 March 1916, the remaining Mounted Brigades were numbered in a single sequence. As a consequence, the 2nd South Midland Mounted Brigade was redesignated as 6th Mounted Brigade. The brigade served with the Western Frontier Force from January to October 1916. It joined the newly formed Imperial Mounted Division in January 1917 and took part in the First and Second Battles of Gaza.