Chan Yui Chong joined the Hong Kong wheelchair fencing team in 2002. Chan took up the sport after being inspired by a music video featuring a fencer. When at the 2004 Summer Paralympics in Athens, Greece, she won three gold medals and a silver in the épée B at the age of 21. She won two further gold medals at the 2008 Games in Beijing, China, including a defeat of China's Yao Fang in the final of the épée B.