He was the third son of Owen Wynne, who settled in Ireland about the year 1688, having previously lived in Wales. In 1688 he was serving in the army of James II, but being a Protestant, he transferred his allegiance to the Prince of Orange on the breaking out of the Glorious Revolution. He was with Major-General Kirke's force sent from England to the relief of Londonderry, and he also took some part in the defence of Enniskillen, and served through the War in Ireland.