Francine Niyonsaba (born May 5, 1993) is a Burundian runner who specializes in the 800 metres. She is a 2016 Olympic silver medalist in the 800 metres. Her silver medal was the first Olympic medal for Burundi since 1996. Niyonsaba finished second in 800 meters 7 race series of 2016 Diamond League. She improved her personal best to 1:56.24 at 2016 Herculis meet.