The regiment returned to Tennessee for the Knoxville Campaign. The unit fought in numerous conflicts in the Shenandoah Valley before being disbanded around April 15, 1865. It reported 9 killed, 43 wounded, and 5 missing at Fort Donelson, and 3 killed and 16 wounded at Fayetteville. Only a handful remained after the Battle of Waynesboro, Virginia, in March 1865.