The 2/2nd Anti-Tank Regiment was an Australian Army anti-tank artillery regiment that was raised for service during the Second World War. Formed in 1940 in Brisbane, Queensland, the regiment was assigned to the 7th Division and was deployed to North Africa in 1940, and subsequently undertook defensive duties in Egypt in 1941, before taking part in the Syria–Lebanon campaign. Garrison duties were undertaken in Syria, before the regiment was back to Australia in early 1942. It later fought against the Japanese in New Guinea and on Borneo before being disbanded in 1946.