From June 2018, he held senior positions in various government agencies. In May 2020, he was appointed the deputy director of the Armenian National Security Service (NSS), and on 8 June 2020, he was promoted to the director of the Armenian NSS. Kyaramyan was dismissed from this post on 8 October 2020, during the 2020 Nagorno-Karabakh War. He had reportedly been appointed the commander of the Armenian forces in Shusha, during the three-day long battle over the city, despite having no military experience. Then, on 6 November, he left Shusha, stating that his duties in the region were completely fulfilled. On 24 December 2020, he was appointed deputy chairman of the Armenian Investigative Committee.