During March, the ship was involved in Operation Lustre, the transportation of Allied troops and materiel to reinforce Greece. On 27 March, "Vendetta" was involved in the Battle of Cape Matapan, where Italian warships attempted to disrupt the Allied troop movements. "Vendetta" played little part in the battle as engine problems forced the destroyer to first withdraw from the destroyer force to the main battle fleet, then retreat to Alexandria for repairs. The ship returned to duty on 21 April, but the change of Allied fortune in the Greek Campaign forced the withdrawal of most of the troops landed during Lustre, and "Vendetta" became involved in Operation Demon, the evacuation from Greece to Crete, over the course of April. During May, the destroyer served with the Allied battle fleet of Crete attempting to deny German air superiority during the battle of and evacuation from Crete.