The 2nd Virginia fought at many famous battles throughout the conflict. In addition to First Manassas, it fought at Second Manassas (after First Kernstown and Jackson's Valley Campaign and with the Army of Northern Virginia from the Seven Days' Battles to Cold Harbor). It reported 90 casualties at First Kernstown, 25 at Cross Keys and Port Republic, 27 at Gaines' Mill, and 77 at Second Manassas. However, during part of the Maryland Campaign of 1863, it was detached to Martinsburg as provost guards. The regiment lost 2 killed and 19 wounded at Fredericksburg, had 8 killed and 58 wounded at Chancellorsville, and had about eight percent of the 333 men engaged at Gettysburg disabled. Later, the unit was involved in Jubal Early's operations in the Shenandoah Valley and finally surrendered at the end at Appomattox Court House on April 9, 1865, with 9 officers and 62 men. A notable death from the Regiment was that of Private John Wesley Culp, who was killed on his uncle's farm in Gettysburg (hence "Culp's Hill").