After the destruction, the inhabitants founded New Pleuron (ἡ νεωτέρα Πλευρών) was situated at the foot of Mount Aracynthus. The founder of the city was most probably Pantaleon of Pleuron, strategos of the Aetolian League in 242/41, 235/34, 228/27, 222/21 and 214/13 BCE. Some time after the defeat of the Aetolian League in the Roman–Seleucid War, the citizens of Pleuron asked the Roman Senate a special permission to join the Achaean League. After the Achaean defeat and the destruction of Corinth in 146 BCE Pleuron became part of the Roman Republic. During the Imperial age the uprisings in Aetolia continued.