Along with other towns in southern Thessaly such as Thaumakoi and Pharsalus, in the mid-1320s Gardiki came briefly under the rule of the Catalan Company, which had taken over the Duchy of Athens in the aftermath of Halmyros. Latin bishops of the "Dioecesis Cardicensis" are still mentioned in 1363 and ca. 1396. The town surrendered to the Ottoman Turks after the fall of Euboea in 1470, and its inhabitants were deported to Constantinople.