The regiment saw service in the Gwalior War of 1843, fighting at the Battle of Mahrajapore (29 December) that saw a British victory against the Mahrattas. The regiment saw extensive service in the First Sikh War in 1845. This war saw the most battle honours awarded to the regiment in a single campaign. It was involved in the first engagement of that conflict, at Mudki (Moodkee), where the regiment's commanding officer, Lieutenant Charles Digby Dawkins, was killed. The regiment took part in the subsequent battles of the war; at Ferozeshah, Aliwal, and the last battle of the war, Sobraon. It was also active during the Indian Mutiny of 1857.