From 1808 to 1813, the regiment and the rest of the 1st Dragoon Division (now under General of Division Victor Latour-Mabourg) along with much of the Reserve Cavalry Corps (under Jean-Baptiste Bessières) served in the Peninsular Campaign. There, they fought many small skirmishes with the Spanish, and saw action in several major battles. They began their campaign at the First Siege of Zaragoza in the summer of 1808, followed by the Battle of Tudela on 23 November. In 1809, they fought in the Battle of Uclés on 13 January, the Battle of Medellín on 28 March, the Battle of Talavera on 27–28 July, and the Battle of Almonacid on 11 August. On 27 September 1810, the 2nd Dragoon Regiment fought at the Battle of Bussaco, in 1811 it fought at the Battle of Chiclana on 5 March and the siege of Elvas later that year, and on 21 June 1813 it fought in the Battle of Vitoria. A small detachment served in the French invasion of Russia in 1812 as part of Marshal Pierre Augereau's reserve XI Corps.