Following Hell in a Cell, Kane reunited with The Undertaker to feud with The Wyatt Family. At Survivor Series, The Brothers of Destruction defeated Bray Wyatt and Luke Harper in a tag team match. Kane was the seventh entrant in the 2016 Royal Rumble match, and was eliminated by Braun Strowman. At Fastlane, Kane teamed up with Big Show and Ryback to defeat The Wyatt Family. At WrestleMania 32, Kane participated in the André the Giant Memorial Battle Royal, and was the runner-up, being eliminated by eventual winner Baron Corbin. On July 19 at the 2016 WWE draft, Kane was drafted to the SmackDown brand. At Backlash in September, Kane defeated Bray Wyatt following interference by Randy Orton. At Survivor Series, Kane defeated Luke Harper on the kick-off show. A rematch between the two was made on the November 29 episode of "SmackDown Live", in which Kane was once again victorious.