From 1997 to 2002, Zuberi served with The Black Watch, a Canadian Forces reserve unit, and assisted his compatriots during the 1998 Ice Storm. After graduating from Concordia University in 2004, he spent a year working as an English teacher in Kuwait. Upon his return to Canada in 2006, he joined the Ottawa office of the not-profit and non-partisan National Council of Canada Muslims (formerly known as the Canadian Council on American-Islamic Relations (CAN-CAIR)), Canada's leading Muslim advocacy organization, as the Media Relations and Human Rights Coordinator. After graduating from law school in 2014, Sameer was appointed as diversity and engagement officer at McGill University’s Faculty of Medicine where he also was an elected member of the Senate. While at McGill, he worked to promote diversity and inclusion of Black and Indigenous students as well as students from lower socioeconomic backgrounds and those from rural Quebec.