Il Volo performed the song for the first time during the 65th Sanremo Music Festival on 11 February 2015. During the final night of the song contest, held on 14 February 2015, "Grande amore" finished in first place, receiving 39.05% of votes on the last round of the competition, beating the remaining top three entries, Nek's "Fatti avanti amore" (35.38%) and Malika Ayane's "Adesso e qui (nostalgico presente)" (25.66%). According to the final voting results, Il Volo won mostly thanks to the televotes (40% of the final voting results share), receiving 56.1878% of votes, while only 22.9167% of votes by the experts jury (3rd), and 32.3333% of votes by the popular jury (2nd).