The 48th Pennsylvania participated in several further battles of the Petersburg campaign in 1864: Globe Tavern (August 18–21), Peebles's Farm (September 29–October 2), and Boydton Plank Road (October 27–28). At the Third Battle of Petersburg on April 2, 1865, regimental Surgeon William R. D. Blackwood removed wounded comrades from the battlefield under heavy fire, for which he was later awarded the Medal of Honor. After occupying the city of Petersburg, the unit marched to Farmville, Virginia, on April 3–9. The 48th Pennsylvania returned to the Petersburg and City Point area on April 20–24, then moved on to Alexandria, Virginia, on April 26–28.