The family has produced several military officers and intellectuals. Many of them made career in the Imperial Russian service. A notable example was the seasoned prince Kaikhosro Mikeladze who organized a volunteer company of his kinsmen to fight the invading Ottoman army during the Eastern War (1853–56). Later in the 19th century and early in the 20th, seven of the Mikeladze attained to the rank of general in the imperial army. These were: Almaskhan Otiyevich Mikeladze (1834-1915), Dmitri Otiyevich Mikeladze (1838-1910), Nikolay Romanovich Mikeladze (1841-1898), Alexander Konstantinovich Mikeladze (1863-1919), Konstantin Almaskhanovich Mikeladze (1866-1914), Alexander Platonovich Mikeladze (1867-1928), and Vyacheslav Artemiyevich Mikeladze (1874-1951), the latter also being an artillery specialist in the Red Army. Shalva Yefemovich Mikeladze (1895-1976) was a great mathematician. By Simone Mikeladze, numerous other noted individuals are known, such as Grigor Mikeladze, colonel in the Iranian army, his brother Konstantin Mikeladze who was also Iranian military commander, as well as their brother Yevgeniy Semenovich Mikeladze (1903-1937), who was a conductor and was killed during the Great Terror. His son is a documentary director Vakhtang Yevgenievich Mikeladze (1937- nowadays).