García has been a member of every European Ryder Cup team since 1999, with the exception of 2010, and has a career record at the Ryder Cup of 22–12–7 (). He has been in six winning sides and his singles win in 2018 made him the all-time Ryder Cup points leader, with 25½ points in 9 appearances, overtaking Nick Faldo's 25 points in 11 appearances.