The regiment was engaged both days, April 6–7, 1862, at the Battle of Shiloh, where it suffered 33 killed and 177 wounded. It participated in the Siege of Corinth, Mississippi, and fought at Stones River, Chickamauga and Missionary Ridge. It was assigned provost (police) duty at Chattanooga, Tennessee, before being mustered out on September 14, 1865.