Grenada sent two athletes, Alleyne Francique and Joel Phillip, as part of their delegation to represent it in the Men's 400m sprint. Francique participated in the fifth heat during the 17 August qualification round, ranking sixth of eight athletes. Francique earned a time of 46.15 seconds, which was 1.19 seconds slower than American runner Lashawn Merritt, the first-place runner in the heat, who would later earn gold in the event. Overall, Francique ranked 35th of 55 athletes. He did not progress to quarterfinals.