Isa Gendargenoevsky () (born 1795, Gendergen, Chechnya – died 1845, Urus-Martan, Chechnya) was a Chechen general during the Russo-Caucasian War, who commanded the Eastern and Central Fronts. Isa was of the Gendargenoy teip and Appaz-Nek'e (Branch of a teip).