Having played over 20 seasons with the senior national team, Sinclair has played in five FIFA Women's World Cups (USA 2003, China 2007, Germany 2011, Canada 2015, France 2019) and four Olympic Football Tournaments (Beijing 2008, London 2012, Rio 2016, Tokyo 2020). She has been shortlisted for FIFA Women’s World Player of the Year seven times, in 2005, 2006, 2007, 2008, 2010, 2012, and 2016.