On 21 November 2010 Jô made a rare start for Manchester City in his team's 4–1 win over Fulham. Jô also featured in Manchester City's 3–1 win away to West Ham before Christmas and scored City's only goal in a 1–1 draw with Juventus in the UEFA Europa League. City won the 2010–11 FA Cup, and despite being left out of the squad for the final, he contributed five appearances earlier in the cup run.