In 1507, Palu aligned itself with Safavid Iran. As a result of the war between the Ottoman Empire and the Safavid State, culminating in defeat for the Safavids at the Battle of Chaldiran, Palu was defeated by the Ottoman Empire in 1514. Cemşid Bey participated directly in the war. In 1516, Cemşid Bey, following the recommendation of Idris Bitlisi, pledged loyalty to the Ottomans. With the help of Karaçinzade Ahmet Bey, he took the hands of Arabşah from Kızılbaş in 1517. After this date, Palu beys were under the rule of the Ottomans.