Karjakin won the 2012 World Rapid Chess Championship, and the Norway Chess tournament in 2013 and 2014. He competed at the Candidates Tournament 2014, placing second. He won the Chess World Cup 2015, thus qualifying for the Candidates Tournament 2016. He won the tournament and earned the right to challenge for the World Chess Championship. In November 2016, he lost the championship match to Magnus Carlsen in the rapid tiebreaks after drawing 6–6 in the classical games. He won the 2016 World Blitz Chess Championship. He participated in the candidates tournament again in 2018, placing third.