When the Red River Campaign commenced in mid-March, the brigade crossed to Alexandria and retreated towards Natchitoches once again. Distinguishing itself in the attack at the Battle of Mansfield on 8 April, the regiment was in reserve with the brigade for most of the day on 9 April during the Battle of Pleasant Hill, being involved in desultory action. In the subsequent Battle of Yellow Bayou on 18 May, the regiment suffered many casualties. With the brigade, it marched to Monroe in August and moved into southern Arkansas. Late in 1864, the brigade returned to Alexandria through Minden. It camped on Bayou Cotile May 1865, when the regiment marched to Mansfield and disbanded there on 19 May, just before Taylor surrendered his command.