On 22 January 1944, "Sigsbee" sailed out of Pearl Harbor with Task Force 52 (TF 52) to participate in the assault and capture of Kwajalein, Marshall Islands. The destroyer bombarded Ennylabegan Island on the morning of 31 January and, that evening, "Sigsbee" and "Ringgold" (DD-500) entered the lagoon to protect American shipping and provide call-fire for troops ashore. The destroyer remained in the Marshall Islands until 1 March when she departed for Efate. "Sigsbee" sortied from there, on 20 March, with TF 37 to participate in the bombardment of Kavieng, New Ireland.