Colin Tilley directed an accompanying video for the song, which was released on August 19, 2014. Following the video's release, it broke the 24-hour streaming record on Vevo by accumulating 19.6 million views in its first day of release. In 2021, Anaconda became first music video for a solo female rap song to hit 1 billion views on YouTube. To further promote the song, Minaj performed it live at the 2014 MTV Video Music Awards and also performed it at Fashion Rocks and the iHeartRadio Music Festival. "Anaconda" was nominated for Best Rap Song at the 2015 Grammy Awards. The song was also nominated for two categories at the 2015 MTV Video Music Awards, Best Female Video and Best Hip-Hop Video, winning the latter.