In May 2020, Crump began representing the family of George Floyd, a 46-year-old unarmed African American who died due to asphyxiation caused by Minneapolis Police Department officer Derek Chauvin, who restrained Floyd with a knee to the neck for 9 minutes and 29 seconds. Derek Chauvin, the officer convicted of having killed Floyd, was initially charged with third-degree murder and second-degree manslaughter; however, an additional second-degree murder charge was added 10 days later, and the three officers also present at the scene were subsequently charged with "aiding and abetting second-degree murder and aiding and abetting second-degree manslaughter." In June 2020 Crump testified before the U.S. Senate Judiciary Committee about the George Floyd case and the discriminatory treatment of African Americans by the U.S. justice system.