She was a philanthropist. She donated substantial amounts of money to create public health nursing programs in Chicago, Hanover County, Virginia, New York City, and Washington, D.C. She was a donor to the endowments of Associated Charities of the District of Columbia. She regularly gave to the Chicago Symphony Orchestra (which her brother Bryan Lathrop was also a benefactor of), and continued to regularly give to the Art Institute of Chicago. She endowed the Page-Barbour Lectures at the University of Virginia She contributed to Episcopal churches, including Washington, D.C.'s St. John's Episcopal Church. In 1915, she organized a large relief program to serve the victims of the 1915 Avezzano earthquake in Italy. She worked to provide relief to the civilian and military casualties in Italy of World War I.