In 1959, the 19-year-old signed with Real Madrid, where he would remain for the following 11 campaigns. Behind Francisco Gento in the queue for selection at both club and international level, Bueno featured infrequently for the "Whites", never appearing in more than nine league games in any season except his last, where he also scored a career-best seven goals to help the side to a fourth-place finish. Despite this, the club itself credits him with eight Primera División titles, as well as two national cups and two European Cups, though he did not take part in any of the finals (he did play in one leg of their 1960 Intercontinental Cup victory). He left Real Madrid in the summer of 1971 with competitive totals of 119 matches and 27 goals.