By the beginning of May, the futility of the Bermuda Conference had become apparent. Days later, Zygielbojm received word of the suppression of the Warsaw Ghetto Uprising and of the Ghetto's final liquidation. He learned that his wife Manya and 16-year-old son Tuvia had been killed there. On 11 May, at his home in west London, Zygielbojm committed suicide with an overdose of sodium amytal, as a protest against the indifference and inaction of the Allied governments in the face of the Holocaust.