Mukherjee was sidelined from the INC following the assassination of Indira Gandhi. Although he was much more experienced in politics than Indira's son, Rajiv Gandhi, it was Rajiv who gained control. Mukherjee lost his position in the cabinet and was sent to manage the regional West Bengal Pradesh Congress Committee. He was considered to be Indira's likely successor and, siding with those within his party who aligned themselves against Rajiv Gandhi, Mukherjee was sidelined and eventually expelled from the mainstream.