On 8 August 2014, Cissokho signed a four-year deal with Premier League club Aston Villa. He impressed during his debut – the first match of the 2014–15 Premier League season against Stoke City, which Villa won 1–0. On 23 August 2014, in the match against Newcastle United, Cissokho suffered an ankle injury, sidelining him for one week. On 20 September 2014, he scored an own goal while attempting to clear Arsenal's Kieran Gibbs' shot. On 24 February 2015, he sustained a groin/pelvis injury during training, sidelining him for two months. He made a total of 27 appearances and helped Villa reach the FA Cup final.