At Buffalo, Sokoli moved to the defensive line full-time. When he committed to Buffalo, he stood at 6'5" and weighed 220 pounds. By his junior year, he weighed 300 pounds. He credited this to a diet of 7,000 calories per day. He redshirted during his freshman year. By his junior year, he had become a starter on the line and was an integral part of a Buffalo pass rush which was led by future first-round draft pick linebacker Khalil Mack. Sokoli would help Buffalo to the 2013 Famous Idaho Potato Bowl that season, its second bowl appearance ever and first since the 2008 season. During his senior year, he played in the 2015 Medal of Honor Bowl. He majored in Business Administration and said that he would like to work on the New York Stock Exchange if he could not make a living playing football.