Cain/LeDuc received three Challenger Series assignments. After placing fourth at the 2016 Nebelhorn Trophy and 2016 Finlandia Trophy, they were awarded the bronze medal at the 2016 Golden Spin of Zagreb, where they upgraded their twist from a double to a triple. Cain stated, "We just started rotating it days before we left for that competition." She had never performed it in competition during her earlier partnerships. They placed third at the 2017 US Figure Skating Championships. At the 2017 Four Continents Championships, they placed ninth.