She was called to Spain's 2019 Women's World Cup squad days after being discharged from a long-term injury on her right foot. She sat out the first match against South Africa as a precaution for her recently healed injury. She made her World Cup debut in the next match, a group stage clash against European powerhouse Germany, subbing on in the 65th minute for Silvia Meseguer. She then started and played all 90 minutes of Spain's next two matches- a draw in the final group stage match against China and Spain's first ever knockout match of a Women's World Cup against the United States. Spain and Guijarro fell in the Round of 16 to the eventual tournament winners despite putting up a well-fought performance.