"Pola" initially served as the flagship of the 2nd Squadron, and in 1940 she led the squadron during the battles of Calabria and Cape Spartivento, in July and November, respectively. During the latter engagement she briefly battled the British cruiser . "Pola" was thereafter reassigned to the 3rd Division, along with her three sister ships. The ship took part in the Battle of Cape Matapan in late March 1941. During the battle, she was disabled by a British airstrike. Later, in a fierce night engagement in the early hours of 29 March, "Pola", "Zara", "Fiume", and two destroyers were sunk by the British Mediterranean Fleet with heavy loss of life.