In May 2019, he was included by manager Tite in Brazil's 23-man squad for the 2019 Copa América on home soil. Throughout the tournament, he only conceded one goal in six matches, as Brazil went on to win the title. The only match in which Alisson failed to keep a clean sheet was the 3–1 final victory against Peru on 7 July, at the Maracanã Stadium, in which he was beaten by a Paolo Guerrero penalty. Following the tournament, Alisson was honoured with the Best Goalkeeper Award for his performances.