During the First Mithridatic War, Flavius Fimbria defeated Mithridates VI of Pontus's forces under his son also known as Mithridates along the Rhyndacus in 85 BC. During the third, Lucullus again defeated him at the Rhyndacus in 73 or 72 BC. Under Manuel I, the Byzantine Empire based their main Anatolian army at Lopadion (modern Uluabat) on the Rhyndacus. After the sack of Constantinople during the Fourth Crusade, the Latin emperor Henry won another battle there against the Nicaean Empire on October 15, 1211.