After his fall Loftus lived at or near his small property at Coverham in Yorkshire. His son Edward had married Jane Lyndley, daughter and heiress of Arthur Lyndley of Middleham, and seems to have been then in possession of Middleham Castle, Yorkshire. In 1641 the ex-chancellor was one of several Irish lords and gentlemen living in England who petitioned Parliament against disseminators of false news from Ireland. The outbreak of the Irish Rebellion in 1641 rendered his Irish estates worthless; like so many of Strafford's enemies who helped to bring about and then rejoiced in his destruction, he found that Strafford's death precipitated the collapse of the stability of the society he had lived in. He died at the beginning of 1643, and was buried in Coverham Church.