Originally a working-class neighbourhood (its inhabitants were mostly workers of the Wuehrer Brewery and the freight yard), it has been a popular, left-oriented area. During World War II San Lorenzo was heavily bombed by Allied planes (on 1943-07-19); the only massive bombing of Rome during the war (though not the only air raid on the city), it aimed at disrupting the railway communication pivoting on the nearby huge freight yard; however, it caused also extensive damage to the buildings of the district (including the Policlinico Umberto I and the basilica itself) and killing some 1,500 people.