Della Monica/Guarise were scheduled to compete on the Grand Prix at the 2020 Internationaux de France, but the event was cancelled due to the pandemic. They placed eighth at the 2021 World Championships in Stockholm. They were later named to the team for the 2021 World Team Trophy. On April 8th, he was named as team captain. Finishing the season at the Trophy, they placed second in the short program and fourth in the free skate, while Team Italy finished in fourth place overall.