On the night of 14/15 February 1918, "Melpomene", together with the destroyers , and was patrolling on the East Barrage Patrol, one of two standing patrols protecting the Dover Barrage, while two more carried out the West Barrage Patrol and three more destroyers and a light cruiser were on standby in the Downs when seven German destroyers, in two groups attacked the Dover Barrage. The Germans sank one trawler and seven drifters while severely damaging a further one trawler, five drifters and the minesweeper . One of the German groups encountered "Melpomene"s group and was spotted by "Amazon". "Amazon" challenged the Germans, three times, but despite receiving no response, still assumed they were friendly ships, allowing the Germans to escaped unhindered. "Melpomene" took part in the Raid on Zeebrugge on 23 April 1918, escorting Motor Launches laying smokescreens. While the attack on Zeebrugge was partially successful, with the entrance to the Zeebrugge docks partially obstructed by blockships, the parallel raid on Ostend was a failure, and a second attempt to block Ostend was made on 9/10 May. "Melpomene" formed part of the escort force for this mission, which again was unsuccessful, with the blockship not blocking the entrance channel to the locks.