The 69th fought in Grant’s Overland Campaign, again losing heavily. At the Battle of Spotsylvania Court House, Lieutenant Charles McAnally of Company D captured a Confederate battle flag. He was later awarded the Medal of Honor for this act, becoming the only soldier of the 69th so decorated. After the Battle of Cold Harbor, the 71st Pennsylvania was merged into the 69th. During the Siege of Petersburg, the Philadelphia Brigade was broken up, with the 72nd Pennsylvania mustered out of service and the 106th reduced to a single battalion. The 69th participated in the pursuit of the Army of Northern Virginia during the Appomattox Campaign. The regiment was mustered out at Ball’s Cross-Roads, near Washington, D.C., on July 1, 1865. Of the original 1,000 men mustered into service at the formation of the regiment, only 56 remained at Appomattox.