When Camillo's father died, in 1639, the prospect of a marriage to perpetuate the lineage was explored. This remained the intention after his uncle's election to the papacy. After negotiations had begun for the wedding of his sister Costanza to Niccolò Ludovisi, belonging to the pro-Spanish faction, a potential bride for the young Pamphili was sought in the pro-French faction. Olimpia Maidalchini advocated for the candidacy of Taddeo Barberini's daughter, Lucrezia, then twelve years old. The move was designed to mend the rift between the Pamphili and the Barberini which had developed after Pope Innocent's election (he had the Barberini investigated for misappropriation of funds during the First War of Castro).