Wambach competed in four FIFA Women's World Cup tournaments: 2003 in the United States, 2007 in China, 2011 in Germany, and 2015 in Canada, being champion of the last edition; and two Olympics tournaments: 2004 in Athens and 2012 in London, winning the gold medal on both. All together, she played in 29 matches and scored 22 goals at these five international tournaments. She played college soccer for the Florida Gators women's soccer team and helped the team win its first NCAA Division I Women's Soccer Championship. She played at the professional level for Washington Freedom, magicJack, and the Western New York Flash.