A few months later Antigua was afflicted by the 1717 earthquakes damaging the church and the cloisters. After repairs, the monastery housed 35 friars in 1740. The complex suffered again in the 1751 earthquakes and more so in the devastating Santa Marta earthquakes of 1773. The church lost its base wall and most of the presbytery and the crossing, while the aisles, choir and its upper side were render useless.