Henry Clay Hooker (January 10, 1828 – December 5, 1907) was a prominent and wealthy rancher during the American Old West who formed the first and what became the largest American ranch in Arizona Territory. After growing up on the east coast, he married and traveled to California, where he established a hardware store in Hangtown. When it burned, he left for Arizona Territory where he partnered with others to supply cattle to the Army and Indian Agencies. When one of the herds stampeded, he found them in a verdant valley. He established the Sierra Bonita Ranch there. It became one of the largest ranches in the Territory and state of Arizona and was held by family members for several generations. He was a personal friend of Wyatt Earp and aided him after the Earp Vendetta Ride.