Her professional career includes time with the Miami Heat and the Miami-Dade Expressway Authority as a Communications Director. For several years, Polo took a professional hiatus as she has dedicated her time and energy to raising her son, CJ. In February 2018, moved by the tragedy of the Parkland shooting, Polo filed to run for office as a Democratic candidate. Although a clear underdog in a Republican district since 1998, she won the election on November 6, 2018. She secured 53% of the vote while her closest rival Frank Mingo, a Republican candidate secured 47%. In August 2019, Republican Tom Fabricio announced his intention to run against Polo for the seat. Polo's push to have Florida legislators vote to hold a special session discussing gun laws did not receive the appropriate amount to move forward.