The Cardinals acquired Freese before the 2008 season. He made his MLB debut on Opening Day 2009 due to an injury to starting third baseman Troy Glaus. Despite suffering his own injuries in the minor leagues and in his first two MLB seasons, Freese batted .297 with 10 home runs and 55 RBIs during 2011, a season capped off by the Cardinals' 2011 World Series championship over the Texas Rangers. The next season, he batted .293 with 20 home runs and was selected to his first MLB All-Star Game. Freese authored a 20-game hitting streak in 2013, but back injuries limited his effectiveness, and the Cardinals traded him to the Angels following the season. He played for the Angels for two seasons before signing with the Pirates in March 2016. The Pirates traded Freese to the Dodgers in 2018, and he retired after the 2019 season.