From Indianapolis, the Regiment was transferred by train to Baltimore. Along the way, the Regiment busied itself by guarding various bridges along the Baltimore and Ohio Railroad. Upon arriving in Baltimore, Col. Brown ordered the Regiments' weapons to be loaded and on half-cock, essentially indicating a preparedness to fire. This was due to the recent Baltimore riot of 1861, which was led by a group of Confederate sympathizers against the Union troops stationed in the city. Col. Brown, feeling that the populace might still be hostile to Union troops, ordered the regiment to load their weapons. From Baltimore the regiment was sent by steam ship to Fort Monroe, where they were camped until September 26, 1861.