Canó made his debut for the Mariners on March 31, going 2-for-4 with a double. Canó recorded his first RBI for the Mariners on April 2. On July 6, Canó was named the American League starting second baseman for the 2014 Major League Baseball All-Star Game. This marked Canó's sixth career All Star selection, and his fifth consecutive. Canó finished the season with a .314 batting average with 14 home runs and 82 RBI. During August, he began to suffer from gastrointestinal symptoms that were later diagnosed as resulting from an intestinal parasite.