After the defeat at Pea Ridge, the regiment fell back to the Van Buren, Arkansas, area. In late March, the regiment transferred to Des Arc, Arkansas. Crossing the Mississippi River, the regiment reached Memphis, Tennessee, on April 7, but was soon sent to Corinth, Mississippi, where a roll call was performed on May 5, determining that 450 men of the regiment were present for duty. On May 9, the regiment was present at the Battle of Farmington, but did not see much action. In late May, the Siege of Corinth ended when the Confederates evacuated the town, and the 3rd Missouri Infantry spent the summer stationed at various points in northern Mississippi. Price's army then moved to Iuka, Mississippi, where it was trapped by Union forces. At the Battle of Iuka on September 19, the regiment was subjected to artillery fire, but was not otherwise engaged. After the battle, the Confederates were able to escape from the Union trap. Price and Major General Earl Van Dorn then united and moved to retake Corinth.