On 8 July the 49th Mixed Brigade became part of the vanguard at the Battle of Brunete and after three days the brigade was placed under the A Division "(División A)" of the V Army Corps of the Central Army. Its mission was to advance from Portillera de las Rozas until the "Vértice Cristo" along the Majadahonda-Boadilla del Monte road until reaching the "Vértice Manilla" behind Romanillos. On 12 July the brigade crossed to the right flank and after two days it was made part of the Durán Division. During the night of the 24 to 25 July it relieved the 10th Mixed Brigade at the Perales River. Towards the final phase of the fight at Brunete it was placed under the V Army Corps and at the end of the battle it became part of the XLVII Division of the XVIII Army Corps.