His second season began with the 2015 Supercoppa Italiana, playing the full 90 minutes of a 2–0 loss to Juventus in Shanghai. In September, he picked up a knee injury on international duty but was passed fit to play a further match for the Netherlands, infuriating Lazio's medical staff. He did not make a sufficient recovery, and was subjected to an operation the following month. In November, it was confirmed that he would miss the next six months due to the injury.