On 28 August 2020, Nketiah was in the starting 11 in the 2020 FA Community Shield, which Arsenal clinched a 5–4 victory over Liverpool in the penalty shootout after the match was 1–1 after 90 minutes. On 19 September, he came on as a substitute in the 77th minute and scored the late winning goal in a 2–1 win against West Ham United in the Premier League, that was also his first goal in the 2020–21 season.