He won the men's individual road race event at the 2016 Summer Olympics, and has won other one-day races such as Paris–Roubaix, Gent–Wevelgem and E3 Harelbeke in 2017, the 2016 GP de Montréal and Omloop Het Nieuwsblad in 2016 and 2017. In the Grand Tours, Van Avermaet has taken two individual stage wins in the Tour de France, and worn the Yellow Jersey for eleven days during the 2016 and 2018 Tours and won the points classification in the Vuelta a España, with one stage win in the Vuelta a España. Van Avermaet was also the overall winner of the 2017 UCI World Tour.