The regiment was stationed in India between 1857 and 1860 in response to the Indian Rebellion and in Ireland from 1865 to 1870, before fighting in the Second Anglo-Afghan War in the late 1870s. It was deployed to South Africa for service in the Second Boer War in October 1899, and took part in the relief of Kimberley and the ensuing Battle of Paardeberg in February 1900. The commanding officer of the regiment, the 11th Earl of Airlie, was killed at the Battle of Diamond Hill in June 1900. Following the end of the war in 1902 they went to India. Almost 530 officers and men left Cape Town on the SS "Lake Manitoba" in September 1902, arriving at Bombay the following month and was then stationed at Ambala in Punjab.