Along with her three sister ships, , , and , "Ostfriesland" participated in all of the major fleet operations of World War I in the North Sea against the British Grand Fleet. This included the Battle of Jutland on 31 May – 1 June 1916, the largest naval battle of the war. The ship also saw action in the Baltic Sea against the Russian Navy. She was present during the unsuccessful first incursion into the Gulf of Riga in August 1915.