With the outbreak of another war with the Ottomans in 1570, Venice, Spain and the Pope formed the Holy League, which was able to assemble a grand fleet of 208 galleys, 110 of which were Venetian, under the command of John of Austria, half-brother of Philip II of Spain. The Venetians were commanded by Sebastiano Venier. The Turkish fleet, equal in number to the allied one, had sailed up the Adriatic as far as Lesina, and then returned to Lepanto in the Gulf of Patras for provisions. The Christian fleet had assembled at Messina and encountered the Turkish fleet off Lepanto on 7 October 1571. The Christians were victorious, and divided up 117 galleys captured from the Turks. But the Venetians gained no strategic advantage. Philip II was concerned with the balance of power in the eastern Mediterranean and Africa, and was unwilling for the fleet to become involved in the Levant. Famagusta, the last stronghold on the island of Cyprus, had been attacked by the Turks in 1570 and had surrendered before Lepanto. The Turkish commander, Lala Kara Mustafa Pasha, had had the Venetian "provveditore" Marcantonio Bragadin flayed alive. The loss of Cyprus was ratified in the peace of 1573. In 1575, the population of Venice was about 175,000 people, but dropped to 124,000 people by 1581.