Hannover lived at Zaslav, Volhynia, and when that town was attacked by the Cossacks he fled into Polish–Lithuanian Commonwealth, then to Prague and eventually Venice, where he studied Kabbalah under Rabbis Chaim HaKohen, Moses Zacuto as well as RabbiSamuel Aboab. Later he became rabbi of Iași, Moldavia, and afterward, according to Jacob Aboab, he returned to Italy.