Lavezzi was chosen by new manager Alejandro Sabella for Argentina's 23-man 2014 FIFA World Cup squad. He made six appearances throughout the tournament, setting up Messi's match-winning goal against Iran after coming off the bench, as well as Rojo's goal against Nigeria. In the final against Germany he set up a goal for Higuaín, but it was correctly ruled off-side; Lavezzi was replaced by Sergio Agüero at half-time, and Argentina were defeated 1–0 in extra time.