Henry Stafford, 2nd Duke of Buckingham, KG (4 September 1455 – 2 November 1483) was an English nobleman known as the namesake of Buckingham's rebellion, a failed but significant collection of uprisings in England and parts of Wales against Richard III of England in October 1483. He is also one of the primary suspects in the disappearance (and presumed murder) of his nephews, the Princes in the Tower.