In Game 4 (the final game) of the NLDS against the Brewers, Burrell hit two home runs (a three-run game-winning home run against Jeff Suppan and a solo home run against Guillermo Mota) in a 6–2 victory that gave the Phillies their first playoff series victory since 1993. Four days later, in the first game of the NL Championship Series, he hit a game-winning solo home run in a 3–2 victory over the Dodgers. After going hitless in his first 14 at-bats in the World Series, Burrell doubled against J. P. Howell of the Tampa Bay Rays on October 29 in Game 5 (the final game of the series). Burrell was then replaced by pinch-runner Eric Bruntlett, who scored the game's winning run in the 4–3 victory as the Phillies won their first World Series since 1980. After the series, Burrell was chosen to lead the Phillies' World Series parade.