Andreas Palaiologos or Palaeologus (; 1520), sometimes anglicized to Andrew, was a son of Manuel Palaiologos and the only of his two sons to survive until adulthood. Andreas was likely named after his uncle, Manuel's brother, Andreas Palaiologos. Andreas's father had returned from exile under the protection of the Papacy to Constantinople in 1476 and had been generously provided for by Mehmed II of the Ottoman Empire, who had conquered the city from Manuel's relatives in 1453. Although Manuel remained a Christian until his death at some point before 1512, Andreas converted to Islam and served as an Ottoman court official under the name Mehmet Pasha. He was the last certain member of the imperial branch of the Palaiologos family.