Cotton's studio album "Giant", released by Alligator Records in late September 2010, was nominated for a Grammy Award. His album "Cotton Mouth Man", released by Alligator on May 7, 2013, was also a Grammy nominee. It includes guest appearances by Gregg Allman, Joe Bonamassa, Ruthie Foster, Delbert McClinton, Warren Haynes, Keb Mo, Chuck Leavell and Colin Linden. Cotton played harmonica on "Matches Don't Burn Memories" on the debut album by the Dr. Izzy Band, "Blind &amp; Blues Bound", released in June 2013. In 2014, Cotton won a Blues Music Award for Traditional Male Blues Artist and was also nominated in the category Best Instrumentalist – Harmonica.