Three years later, Iannotta made his Paralympic Games debut during the 2016 Summer Paralympics. He earned Team USA's first 2016 Paralympic gold medal in track with a time of 17.17 seconds, beating the previous medalist Raymond Martin. Iannotta ended the Games with a bronze medal in the 400-meter race. The following year, he was named to Team USAs roster for the 2017 World Para Athletics Championships, where he won a bronze medal in the men’s T52 100.