Reid made his Premier League debut on 14 August 2010, starting the whole game, in a 3–0 loss to Aston Villa in the opening game of the season. After making another appearance in a follow–up match, he was dropped from the starting eleven and found himself on the substitute bench, as well as, playing in the reserve side for the next three months. It was not until on 27 November 2010 when Reid made his first team return, coming on as a 50th-minute substitute, in a 3–1 win against Wigan Athletic. Between January and February, he made six starts for the side. Reid played an important role against Nottingham Forest in the fourth round of the FA Cup, assisting a goal for Victor Obinna, who scored a hat–trick, in a 3–2 win on 30 January 2011. He then scored his first goal for the club in a 5–1 win against Burnley in the Fifth Round of the FA Cup on 21 February 2011. After the match, Reid said he dedicated to the victims and his families following an earthquake in Christchurch. Once again, however, Reid spent the rest of the 2010–11 season sidelined from the starting eleven, which saw him placed on the substitute bench, as well as, his own injury concern. In his first season at West Ham United, which saw them relegated to the Championship, he made twelve appearances in all competitions.