In June 2021, Berardi was included in Italy's squad for UEFA Euro 2020. In the opening match of the tournament on 11 June, a 3–0 win over Turkey, his cross led to the opening goal of the game, an own–goal by Merih Demiral. In the following group match on 16 June, he set up Manuel Locatelli for Italy's opening goal in an eventual 3–0 win over Switzerland. On 11 July, Berardi won the European Championship with Italy following a 3–2 penalty shoot-out victory over England at Wembley Stadium in the final, after a 1–1 draw in extra-time; Berardi came on as a substitute for Ciro Immobile in the second half of regulation time, and later scored Italy's first spot-kick in the shoot-out.