Landriscini was born on 16 May 1952 in Bahía Blanca, in Southern Buenos Aires Province. She attained her "licenciatura" on Economic Sciences at the Universidad Nacional del Sur in 1974. She moved to Viedma, Río Negro shortly before the 1976 coup d'état. Following the return of democracy in 1983, Landriscini became employed at the National University of Comahue (UNCo), and rose through the academic ranks to become a professor of economic theory at the Faculty of Economics and Administration.