She was paid off in 1815 only to be recommissioned in 1817 when she was modified to carry 76 guns. At the same time her stern was altered and she was given diagonal bracing on the framing introduced by Sir Robert Seppings. In 1825 she sailed from Portsmouth with Rear Admiral Philip Woodehouse as the new commanding officer of the West Indies station. During 1826-27 she circumnavigated the World under Captain William Parker, but bearing the flag of Rear-Admiral Gage, departing from Spithead for India. At Trincomalee Rear-Admiral Gage was replaced by Commodore Sir James Brisbane as the new South Atlantic (Rio de Janeiro) Station commander-in-chief. However, following Commodore Brisbane's death from a contracted tropical disease, Captain Richard Saunders Dundas of the accompanying 6th rate Survey ship HMS "Volage" took command for the rest of the voyage which saw "Warspite" as the first ship of the line to visit Port Jackson in the colony of New South Wales in Australia. Returning to the station with the Malta squadron late in 1828 she was detached to transport Count Capo d'Istria, President of the Greek republic, to various locations around the Eastern Mediterranean while blockading Navarino, Modon and Coron in coordination with the French and Russian allied squadrons. In this capacity it helped to interdict two Egyptian corvettes at Navarino, one suffering substantial damage when it ignored warning shots and was engaged with the main battery. Captain Parker then participated in several conferences with Ibrahim Pasha to negotiate the withdrawal of Egyptian troops from Greece. In 1831 she was at the South American (Rio de Janeiro) station as the flagship of Rear Admiral Sir Thomas Baker, Captain Charles Talbot, at one time contribution towards salvage of HMS "Thetis" (1817) cargo off Cape Frio in 1830.