The Mexican Inquisition was an extension of the Spanish Inquisition to New Spain. The Spanish Conquest of Mexico was not only a political event for the Spanish, but a religious event as well. In the early 16th century, the Reformation, the Counter-Reformation and the Inquisition were in full force in most of Europe. The Catholic Monarchs of Castile and Aragon had just re-conquered the last Muslim stronghold in the Iberian Peninsula, the kingdom of Granada, giving them special status within the Roman Catholic realm, including great liberties in the conversion of the native peoples of Mesoamerica. When the Inquisition was brought to the New World, it was employed for many of the same reasons and against the same social groups as suffered in Europe itself, minus the Indians to a large extent. Almost all of the events associated with the official establishment of the Holy Office of the Inquisition occurred in Mexico City, where the Holy Office had its own "palace", which is now the Museum of Medicine of UNAM on Republica de Brasil street. The official period of the Inquisition lasted from 1571 to 1820, with an unknown number of victims.