Owomoyela debuted for Jürgen Klinsmann's Germany national side in an Asian tour, playing 90 minutes in a 3–0 win over Japan, on 16 December 2004, in Yokohama. He later was selected in the "Bundestrainer"'s team for the Confederations Cup in 2005, but was unused there and was finally overlooked for Germany's World Cup final squad. In total he collected eleven caps.