Michelle Griglione (born c. 1969) is an American former competitive swimmer who won a silver medal in the 400-meter individual medley event at the 1986 World Aquatics Championships in Madrid, Spain. She barely missed Olympic qualifications in 1984, 1988, 1992, and 1996, finishing in third-fourth places, but she won five medals at the Pan American Games and Pan Pacific championships in 1985, 1987, 1989 and 1995.