In February 2008 Tindall was named in Brian Ashton's squad for the upcoming Six Nations Championship, and thus started for England at outside centre against Wales at Twickenham on 2 February 2008. During the match, he was accidentally kicked in the chest by winger Mark Jones and had to be stretchered off. He had attempted to win possession just as Jones was kicking the ball away, and was ruled out of the tournament with internal bleeding and a perforated liver.