During the First Italian War of Independence the brigade's two regiment were attached to infantry divisions and fought at the battles of Pastrengo, Santa Lucia, Volta Mantovana, , , and Novara. After the conclusion of te war with the Armistice of Vignale on 24 March 1849 the brigade received the returning Cuirassier regiments "Savoia Cavalleria" and "Genova Cavalleria" on 2 April 1849. With the war over the brigade was disbanded on 10 November 1849.