He lost his second match to Mikhail Youzhny in straight sets. Thompson ended up finishing in seventh place after he upset world number 42 Juan Mónaco. This was Thompson's first victory over a top 50 player. Thompson lost in 5 sets to world number 21 Jerzy Janowicz in the first round of the 2014 Australian Open 6–1, 6–4, 4–6, 2–6, 1–6. On 21 January, Thompson was announced in the Australian squad of the 2014 Davis Cup as the back-up player.