DeepMind made headlines in 2016 after its AlphaGo program beat a human professional Go player Lee Sedol, the world champion, in a five-game match, which was the subject of a documentary film. A more general program, AlphaZero, beat the most powerful programs playing go, chess and shogi (Japanese chess) after a few days of play against itself using reinforcement learning. In 2020, DeepMind made significant advances in the problem of protein folding.