Parisse continued his form into the 2008 Six Nations Championship. Parisse won his 50th cap for Italy against England in the 2008 Six Nations Championship at the age of 24. Parisse is also the Italian captain, appointed in 2008 by Nick Mallett in place of Marco Bortolami. In September 2008 Parisse was nominated for IRB International Player of the Year alongside Dan Carter, Ryan Jones, Shane Williams and Mike Blair.