Bonaparte began with an army of 13,000 men; 1,500 were reported missing, 1,200 died in combat, and thousands perished from disease—mostly bubonic plague. He failed to reduce the fortress of Acre, so he marched his army back to Egypt in May. To speed up the retreat, Bonaparte ordered plague-stricken men to be poisoned with opium; the number who died remains disputed, ranging from a low of 30 to a high of 580. He also brought out 1,000 wounded men. Back in Egypt on 25 July, Bonaparte defeated an Ottoman amphibious invasion at Abukir.