The 114th Illinois participated in the Jackson Expedition from 4–19 July 1863. There was a skirmish at Birdsong Ferry on the Big Black River on 4–6 July. The siege of Jackson on 10–17 July ended with the retreat and pursuit of Joseph Johnston's Confederate forces which ended at Brandon Station on 19 July. The regiment lost 7 men killed and wounded during the expedition. The unit returned to Vicksburg where it performed picket duty. On 3 September, the regiment was ordered to Oak Ridge where Confederate partisans captured 2 enlisted men and killed Second Lieutenant Joseph A. McClure on 2 October. On 14–20 October, the 114th Illinois participated in an expedition in the direction of Canton including an action at Bogue Chitto Creek on 17 October. The regiment boarded river transports on 20 November to travel upriver to Memphis. From 26 November 1862 to 5 February 1864, the unit performed provost duty at Memphis.