The regiment participated in the movements around Corinth on the approach of the Union army under General Halleck and suffered 3 wounded and 3 missing or captured. During the Battle of Farmington, Mississippi, 26 May 1862, the 16th Arkansas lost 6 killed or mortally wounded, 4 wounded and 3 missing or captured. In September 1862, it took part in the Battle of Iuka, where 2 men of the 16th Arkansas were wounded and 1 captured. The 16th Arkansas participated in the desperate assault on the Federal lines at the Second Battle of Corinth on October 3–4. 1862 where it lost heavily in the assault on Battery Powell. It reported 13 killed and 29 wounded, including Lieutenant J. H. Berry, who lost a leg in this battle. Shortly after, the regiment was detached from the Missouri brigade and assigned to the Arkansas brigade, commanded by Colonel Jordan E. Cravens, Arkansas troops, at Holly Springs, Miss. It was there again detached and sent with other Arkansas regiments to Port Hudson, Louisiana. On January 7, 1863 Major General Frank Gardner issued General Order No. 5 which consolidated several under strength Arkansas units: