She won the silver medal in the women's road race at both the 2008 and 2016 Summer Olympics, as well as one silver and two bronze medals at the Road World championships. She also holds a record four podium finishes at the Tour of Flanders for Women, with one second and three third places. Despite her amassing of podium places, she won several one-day races, including Omloop Het Nieuwsblad, Ronde van Drenthe, Trofeo Alfredo Binda-Comune di Cittiglio, Omloop van het Hageland, Le Samyn and the Holland Hills Classic.