In 1670, it had the largest brotherhood of all monasteries on Fruška Gora: 90 monks and 12 elders. In 1690, during the Great Serbian Migration, the monks fled the monastery and moved to Szentendre taking valuables, relics and artifacts with them. They returned to Krušedol in 1697. When the Ottomans were retreating in front of Prince Eugene of Savoy during the Austro-Turkish War of 1716-1718, they ransacked the monastery and burned it, but it was rebuilt later.