The Nativity of Holy Theotokos Church is a historic Russian Orthodox church in Afognak, Alaska. The present church is the third Russian Orthodox church built in Afognak, and replaced the second which had been built in the late 1800s. Its construction began in 1901, and was completed in 1905. The community was mostly "washed out" by a 1964 tsunami, and moved to Port Lions, but the church building remained.