The theatre closed temporarily in 1642 at the height of the Barberini Wars of Castro with the Farnese Dukes of Parma which became incredibly expensive for the family and the Holy See. The theatre had not yet reopened before when its patrons, the three Barberini nephews of Pope Urban (Francesco Barberini, Antonio Barberini (Antonio the Younger), and Taddeo Barberini), were sent into exile by the newly elected Pope Innocent X.