In the late Middle Ages, Sieciechów was located on a merchant trail from Sandomierz through Zawichost, to Lithuanian lands. It had a parish church of St. Lawrence, which controlled parishes of large parts of northern Lesser Poland, at such towns, as Kozienice, Stężyca, Dęblin, Zwoleń and Kazimierz Dolny. Sieciechów probably had a defensive wall, and a Vistula river port. Its first known castellan was named Florian, his name was mentioned in 1239. In 1432 King Władysław Jagiełło gave permission for fairs, but period of prosperity ended after the change of the course of the Vistula. As a result, the town no longer controlled the strategic river, and the castle, which was located on a hill right above river bank, no longer fulfilled its role. Furthermore, after the Union of Krewo, Poland was no longer threatened by Lithuanian raids. Sieciechów remained a town until 1869, when the government of Russian-controlled Congress Poland reduced it to the status of a village.