During the Greco-Persian Wars, Daulis was destroyed by the Persians in the invasion of Xerxes I (580 BCE). Its territory was sacked by the Boeotians, who however were unsuccessful in their attempt to assault the city. It was destroyed a second time by Philip II of Macedon, at the end of the Third Sacred War (346 BCE); but it was subsequently rebuilt, and is mentioned in later times as a town almost impregnable in consequence of its situation upon a lofty hill. In , Daulis was attacked by the Aetolians, like the city of Ambrysus. In 198 BCE, the Romans besieged Daulis but, not being able to take it by direct assault since the city had a very strong position on the top of a hill, they had to occupy it by a stratagem. Pausanias relates that the inhabitants of Daulis were few in number, but surpassed all the other Phocians in stature and strength. The only building in the town mentioned by him was a temple of Athena; but in the neighbourhood he speaks of a district called Tronis, in which was the chapel of a hero (heroon) called the Archegetes.