Klose started the season by playing in the 2013 Supercoppa Italiana against Juventus, which ended in a 4–0 loss at Stadio Olimpico. Klose started the league season by playing 83 minutes in team's opening league match of the season, a 2–1 home win against Udinese and scored his first goal of the season on 31 August in a 4–1 away defeat to Juventus. He scored his second league goal of the season on 28 October during the 2–0 home victory against Cagliari.