For his performance as singer Sam Cooke in "One Night in Miami..." (2020), Odom earned Academy Award, BAFTA Award, Screen Actors Guild Award, Critics' Choice Movie Award, and Golden Globe Awards nominations for Best Supporting Actor. He was also nominated for an Oscar and Golden Globe for writing the film’s original song "Speak Now," for which he won Best Song at the 2021 Critics' Choice Awards. Later that year, he received a nomination for a Primetime Emmy Award for Outstanding Actor in a Leading Role in a Limited Series or Movie for his performance in the Disney+ live stage recording of "Hamilton" which was released in 2020.