During the politics of Mary, Queen of Scots, the Homes, like many others, shifted their allegiance more than once. Lord Home had supported the marriage of the Earl of Bothwell to Mary but he later led his men at the Battle of Langside against the queen. Then in 1573 he was arrested and convicted of treason against the young James VI of Scotland. He was released from Edinburgh Castle only after his health had failed, dying a few days later. His son, Alexander, the sixth Lord Home, was devoted to James VI and was several times ambassador to France.