He saw further service during the Seven Years' War, joining the preparations for an attack on Louisbourg in 1757. The attempt was abandoned, but Rous became captain of the 50-gun and saw action at the successful siege in 1758. He went on to take part at the capture of Quebec in 1759, leading Admiral Sir Charles Saunders's fleet up the river, and landing troops for the attack under General James Wolfe. He returned to England in late 1759 with a convoy, and died at Portsmouth on 3 April 1760. He was buried at St Thomas's Church on 6 April 1760.