As mounted infantry, the regiment rode into battle on their horses, but were expected to dismount for battle, and then fight on foot. The regiment fought predominantly against the forces of the Ottoman Turkish Empire. In the Gallipoli Campaign between May and December 1915, they participated in the largest battle of that theatre at Chunuk Bair, and also in the fighting for Hill 60. Evacuated to Egypt, they then took part in the Sinai and Palestine Campaign from 1916 to 1918. The early battles there included those at Romani, Gaza and Beersheba. Later in the war they were part of the force that occupied the Jordan Valley, and took part in the raid on Amman and the raid on Es Salt. Their final war time operation was in connection with the capture of the Turkish Fourth Army. During the four years of war the regiment had 369 dead and 453 wounded, several of those wounded more than once. After the war, the regiment played a minor role in the Egyptian Revolution of 1919, before being disbanded in June 1919.