In 1744, the regiment was present at the Battle of Kloster Maria Schein (28 August), Siege of Prague (2–18 September), and Battle of Patschkau (21 December). In 1745, the regiment fought further at the Battle of Konstadt (20 April) and at the famed Battle of Hohenfriedberg (4 June). At Hohenfriedberg, the regiment defeated three full Austrian infantry regiments, capturing many flasgs. "Oberst" Ewald Wedig von Massow, 17 officers and 631 men were killed. The regiment was awarded with five Pour le Mérite "(Prussia's Highest Military Honour)". The regiment had been reduced to 18 officers, 48 Non-commissioned officers, 22 musicians, and 378 men. Finally, they were present at the Siege of Neustadt (4–12 September) and the Battle of Hennersdorf (23 November).