To start the 2013 season, Ambrose had 11th-place finishes in both the Sprint Unlimited and the Budweiser Duel. Ambrose drove in the top ten for a part of the Daytona 500 but when Kevin Harvick, Kasey Kahne and Tony Stewart crashed out of the race, Ambrose slowed down to avoid being involved in the accident, causing him to drive for the rest of the race further back in the field. He finished in 18th place. He recorded another 18th-place finish at Phoenix and a 22nd-place finish at Las Vegas.