Strasbourg played an important part in Protestant Reformation, with personalities such as John Calvin, Martin Bucer, Wolfgang Capito, Matthew and Katharina Zell, but also in other aspects of Christianity such as German mysticism, with Johannes Tauler, Pietism, with Philipp Spener, and Reverence for Life, with Albert Schweitzer. Delegates from the city took part in the Protestation at Speyer. It was also one of the first centres of the printing industry with pioneers such as Johannes Gutenberg, Johannes Mentelin, and Heinrich Eggestein. Among the darkest periods in the city's long history were the years 1349 (Strasbourg massacre), 1518 (Dancing plague), 1793 (Reign of Terror), 1870 (Siege of Strasbourg) and the years 1940–1944 with the Nazi occupation (atrocities such as the Jewish skeleton collection) and the British and American bombing raids. Some other notable dates were the years 357 (Battle of Argentoratum), 842 (Oaths of Strasbourg), 1538 (establishment of the university), 1605 (world's first newspaper printed by Johann Carolus), 1792 (La Marseillaise), and 1889 (pancreatic origin of diabetes discovered by Minkowski and Von Mering).