Khoury was also renowned for his philanthropic activities and generous donations to charity. He was always committed to help in times of humanitarian crisis or natural hazards and used his influence for fundraising purposes: during the floods of North Lebanon on 22 December 1955, he participated in the committee of dignitaries organizing the relief efforts in Tripoli. Similarly, he was one of the first to donate money during the earthquake of 16 March 1956, which affected the Chouf and South Lebanon regions, and formed a committee to organize fundraising among industrialists. In March 1960, he donated to the Red Cross for the benefit of the victims of the Agadir earthquake. In 1974, he became a member of the National Committee for Victims of Cyprus.