Following their success, the Timbers were expected to be a contender for MLS Cup 2016. Despite the losses of forward Maximiliano Urruti, defender Jorge Villafaña, and captain Will Johnson, the Timbers retained main offensive starters Valeri, Darlington Nagbe, and club top-scorer Fanendo Adi. There were also higher expectations for forward Lucas Melano, who arrived midway through the previous season as a designated player from Valeri's former club Lanús. During the season, Valeri had another productive campaign as he scored 14 goals and earned seven assists. His goals count being second among Timbers players and second among midfielders in MLS. On 28 July 2016, Valeri was named into his second MLS All-Star squad. The All-Stars would take on Premier League side Arsenal. On 10 August 2016, Valeri signed a three-year contract extension with the Portland Timbers.