Barajuen entered the Monastery of Santa María de Buenafuente del Sistal on 16 April 1927, when she was nineteen years old. She remained as a cloistered nun at the monastery for 86 years. In an interview with "Portal de tu Ciudad" Barajuen said that she did not originally intend to become a nun, but entered into religious life at the monastery due to family pressures. She and her fellow nuns were forced to flee the monastery during the Spanish Civil War due to fighting in the region. In August 2011, Barajuen left the monastery for the first time in forty years to meet with Pope Benedict XVI, who was visiting Madrid for World Youth Day 2011. Barajuen had entered the cloistered monastery on 16 April 1927, the same day that Benedict XVI was born.