In his first year of Formula One, Brambilla was as quick as his teammate Stuck, although more accident-prone. In the Swedish GP he ran in fifth until an engine problem. Brambilla finished tied for 18th, last, in the Formula One World Championship standings. In 1975 he amazed many at the Belgian GP, where he led until encountering brakes problems after 54 laps, and at the 1975 Swedish Grand Prix, where he secured pole position until a transmission failure forced him to retire after 36 laps. His great day came at the Österreichring in 1975, when he won a wet Austrian Grand Prix. He spun off and wrecked the nose of his car as he took the chequered flag, and completed his slowing down lap with the front of the car destroyed while waving to the crowd. As the race was shortened, with 60% of it completed, he only received 4.5 points instead of 9 for the win. A more serious accident occurred that season when Brambilla crashed his March through a new curve at Watkins Glen during qualifying for the 1975 United States Grand Prix. He backed into a guard rail afterwards but was unhurt. The session ended at that point with Niki Lauda leading. Before his accident Brambilla was second fastest with a lap of . During 1976 he suffered several accidents and mechanical retirements, collecting only one point at the 1976 Dutch Grand Prix. He qualified his March in 8th position for the 1976 United States Grand Prix West. In the race Brambilla was tapped from behind by Carlos Reutemann before they reached the first turn. He lost the right rear wheel on his March on the 35th lap of the 1976 United States Grand Prix after holding fifth place for a time.