In Week 3 against the New York Giants, Williams had 23 carries for 120 rushing yards in the 38–0 victory. In Week 15 against the New York Jets, he had 168 scrimmage yards and a receiving touchdown in the 30–20 victory. In the 2013 season, Williams had 201 carries, his most attempts since his Pro Bowl season in 2009. However, he did not make much out of these carries, only rushing for 843 yards. He scored three rushing touchdowns, his fewest since his injury plagued season in 2010, and one receiving touchdown. The Panthers finished with a 12–4 record, won the NFC South, and earned a first-round bye with the #2-seed. In the against the San Francisco 49ers, he had five carries for 13 yards in the 23–10 loss.