Shortly after the outbreak of the Greek War of Independence (1821) he supported the uprising by supplying the revolutionaries with firearms, ammunition and food. In 1824 Stavros moved to Greece and the next year he was appointed Chief Cashier of the Executive body of the First Hellenic Republic, under Georgios Kountouriotis. Apart from his financial duties, he joined the armed struggle against the Ottoman Empire by leading an infantry group against Ibrahim Pasha of Egypt. He held the rank of "Chiliarchos" and was in charge of 50 men in central Greece, in order to support the defenders of Missolonghi during its Third Siege. Stavros participated in the Third National Assembly at Troezen (1827) as representative of the regions of Epirus and Central Greece, as well as in the Fifth National Assembly at Nafplion (1831), as representative of Epirus.