The 2nd and 6th Missouri Infantry Regiment (Consolidated) was an infantry regiment that served in the Confederate States Army during the American Civil War. The regiment was formed on October 6, 1863, when the 2nd Missouri Infantry Regiment and the 6th Missouri Infantry Regiment were consolidated. The regiment first saw major action in the 1864 Atlanta campaign, fighting in the battles of Kennesaw Mountain and Peachtree Creek, the Siege of Atlanta, and several smaller actions. After the Confederates retreated from Atlanta, the regiment was part of a force that made an unsuccessful attack against a Union garrison during the Battle of Allatoona on October 5. The regiment then followed General John Bell Hood's Confederate Army of Tennessee into Tennessee, where it charged the Union works at the Battle of Franklin on November 30. At Franklin, the regiment suffered over 60 percent casualties, including the loss of many company commanders. After Franklin, the regiment was detached from the rest of the army to build fortifications, missing the Battle of Nashville. In March 1865, the regiment was transferred to Mobile, Alabama. On April 9, 1865, the regiment was captured at the Battle of Fort Blakely; the survivors of the regiment were paroled at Jackson, Mississippi in May after the Army of Tennessee surrendered.