Reynolds is a staunch supporter of Donald Trump. Reynolds blocked two-thirds of requests from Democratic state Attorney General Tom Miller to join multi-state lawsuits challenging Trump administration policies or to submit amicus briefs in such suits; among the vetoed requests were proposals to challenge Trump policies related to immigration, asylum, abortion, birth control, environmental deregulation, gun policy, and LGBT rights. Reynolds blocked Miller from including Iowa in a legal challenge to the Trump administration's repeal of the Clean Power Plan, an Obama-era regulation that restricted emissions of greenhouses gases (such as carbon) to counteract climate change. In 2018, Reynolds acknowledged that Trump's trade and tariff policies were hurting American farmers (who suffered from a decline in agriculture exports due to tariffs imposed by other nations in retaliation to Trump's tariffs), but then claimed that farmers would ultimately benefit. Reynolds made campaign appearances with Trump during the 2020 presidential campaign; in the November election, Trump carried Iowa, but was defeated nationally by Joe Biden, who won both the electoral vote and the national popular vote. After Trump's loss, Reynolds did not denounce the president's claims of election fraud and refused to acknowledge Biden's victory until January 2021, when the electoral votes were formally counted by Congress. Reynolds condemned the storming of the Capitol, which disrupted the formal counting of the electoral votes, but said many people believed the election was "not valid."