At the beginning of the War of the Fifth Coalition, Hohenzollern received appointment to the command of III Armeekorps in the south German theater. He led his corps at the Battle of Teugen-Hausen on 19 April 1809. He also fought at the Battle of Eckmühl on 22 April. After having traded corps with Johann Kollowrat, he led the II Armee Korps in the Austrian victory at the Battle of Aspern-Essling on 21–22 May. This was the third time that Hohenzollern participated in a defeat of Napoleon, a rare distinction in 1809. In the climactic Battle of Wagram, he continued to lead his corps. In August 1809, Emperor Francis II promoted him to General of Cavalry (full general).