Landram proved to be a capable officer and he participated in the battles of Chickasaw Bayou, Arkansas Post, Champion Hill, Black River Bridge, the siege of Vicksburg, the siege of Jackson, and finally the Red River Campaign. While in command of a division at the Battle of Sabine Crossroads, Landram was captured on April 8, 1864, immediately paroled, and later exchanged July 22, 1864.