Thrakomakedones is situated in the southern foothills of the Parnitha mountains, at the northern edge of the Athens conurbation. It is 5 km northeast of Acharnes and 16 km north of Athens city centre. The 1999 Athens earthquake affected Thrakomakedones, causing severe damage to several houses and a school. During a heatwave, on 7 August 2021 wildfires affecting Greece and Turkey were spreading towards Thrakomakedones; many people left their homes.