Sibusiso Bruno Matsenjwa (born 2 May 1988) is a sprinter from Eswatini. He competed in the 200 metres at the 2012 and 2016 Olympics, but failed to reach the finals. He broke the national record on both occasions and served as the flag bearer for Eswatini during the opening ceremony in 2016. Matsenjwa holds national records over 100–400 m distances. He represented his country at three outdoor and three indoor world championships. Sibusiso also competed at the 2018 Gold Coast Commonwealth Games.