Menstrie Castle was burned by the Royalist James Graham, 1st Marquess of Montrose in 1645, during the English Civil War. It was sold to James Holborne of Menstrie in 1648. A major general in the Scottish army, Holborne had a chequered career during the Wars of the Three Kingdoms. An additional property, named Windsor House, and now demolished, was once situated opposite Menstrie Castle, to serve as a second laird's house. In 1719, most of the Menstrie estate was sold on, but the Holborne family kept the smaller house, probably as a dower house. A stone heraldic panel, from over the door of the demolished house, was preserved, and later built into the gable-end of the residential home now standing on the site. The motto "DECUS MEUM VIRTUS" is still legible, but differs from the motto on the Holborne family crest ("Decus Summum Virtus", roughly translated as "Virtue, the Chief Ornament"). The last surviving heir of the Holborne family of Menstrie was a Miss Mary Anne Holborne of Bath, daughter of the 5th Baronet, who left an endowment of £8000 in 1882, for the church of Menstrie.