Klazomenai is located in modern Urla (Vourla (Βουρλά) in Greek) on the western coast of Anatolia, on the southern coast of the Gulf of İzmir, at about 20 miles west of İzmir. The city was originally located on the mainland at Limantepe, but probably during the early fifth-century BC Ionian Revolt from the Persians, it was moved to the Karantina Island just off the coast. Soon after that, the city of Chyton was founded on the mainland the late fifth-century BC. Both cities had conflictual relations but Alexander the Great eventually connected Karantina island to the mainland with a causeway, the remains of which are still visible.