In 1723, her portrait was painted by Rosalba Carriera during the painter's stay in Modena at the request of her father. The portrait is currently kept in the Gemäldegalerie Alte Meister, Dresden. After the death of her father in 1737, her brother Francesco succeeded him as Duke of Modena. While her brother was fighting in the Russo-Turkish War, Amalia and her sister Benedetta assumed the regency of the duchies.