Located on the western periphery of the Persian Empire, Phoenicia was one of the first areas to be conquered by Alexander the Great during his military campaigns across western Asia. Alexander's main target in the Persian Levant was Tyre, now the region's largest and most important city. It capitulated after a roughly seven month siege, during which many of its citizens fled to Carthage. Tyre's refusal to allow Alexander to visit its temple to Melqart, culminating in the killing of his envoys, led to a brutal reprisal: 2,000 of its leading citizens were crucified and a puppet ruler was installed. The rest of Phoenicia easily came under his control, with Sidon, the second most powerful city, surrendering peacefully.