In the same year he had to resign the management of the adult education center due to the rise of the Nazis. At the request of the board of the Reich Representation of German Jews in Berlin, he joined the latter, where he was mainly concerned with administrative issues and social tasks. After the November pogroms, Eppstein received an invitation from England to lecture in sociology, which he refused because he did not want to leave Germany. In the following period he was arrested several times by the Gestapo.