James Duane (February 6, 1733 – February 1, 1797) was an American attorney, jurist, and American Revolutionary leader from New York. He served as a delegate to the First Continental Congress, Second Continental Congress and the Congress of the Confederation, a New York state senator, the 44th Mayor of New York City, the 1st post-colonial Mayor of New York City and a United States District Judge of the United States District Court for the District of New York. Duane was a signatory of the Continental Association and the Articles of Confederation.