On February 25, 2018, at Elimination Chamber, Bliss won the inaugural women's elimination chamber match, after she successfully retaining her title. In parallel to her activities as a singles wrestler, she took a part of the Mixed Match Challenge tournament with Braun Strowman as her partner, and the duo was able to qualify to the semi-finals of the tournament, where they were defeated by the eventual winners Asuka and The Miz. On April 8 at WrestleMania 34, Bliss lost the title to Nia Jax, ending her reign at 223 days. On May 6 at Backlash, Bliss invoked her rematch clause and challenged Nia Jax for the title, however, she was unsuccessful and suffered a shoulder injury during the match.