The Twin Cam made several appearance in Formula 1 Cosworth Mk.XVI form during the formula that ran from 1961-65. Its first appearance was at the 1963 South African Grand Prix in a Brabham BT6 driven by David Prophet. The engine appeared in two cars in the 1964 British Grand Prix, one being the Gerard Racing Cooper T73 driven by John Taylor and the other the John Willment Automobiles Brabham BT10. The only recorded finish was ninth place at the 1965 South African Grand Prix, again in the Willment Brabham.