When Iraq executed its Invasion of Kuwait in 1991, the 50th Tactical Fighter Wing quickly mobilized its forces for deployment, sending the 10th Tactical Fighter Squadron and 30 F-16C Fighting Falcons as part of Operation Desert Shield on 29 December 1990. On 17 January 1991, 10th Tactical Fighter Squadron aircraft were among the first to strike Iraqi military positions as part of Operation Desert Storm, specifically bombing Al-Taqaddum Air Base, Iraq and gaining air supremacy over the Iraqi Air Force. The squadron was retasked to hunt down Scud missiles, which were striking coalition military targets and Israeli population centers. Throughout the entire campaign, the 10th Tactical Fighter Squadron had only lost one aircraft, with its pilot being taken as a prisoner of war. After hostilities ceased, 10 TFS forces enforced the ceasefire accords through combat air patrols.