Tuktamysheva began her season by placing third in the individual competition of the Japan Open before winning the gold medal at the 2015 International Cup of Nice. Turning to the Grand Prix series, she won silver at Skate Canada International behind Ashley Wagner after placing seventh in the short program but winning the free skate. At the Trophée Éric Bompard in Bordeaux, France, she placed fifth in the short program after falling on a triple Axel. Due to the cancellation of the free skate following the November 2015 Paris attacks, the short program standings were accepted as final. As a result, she finished as the second alternate for the 2015–16 Grand Prix of Figure Skating Final and was unable to defend her title. Tuktamysheva finished first in the 2015–16 ISU Challenger Series standings after winning gold medals at the 2015 Warsaw Cup and at the 2015 Golden Spin of Zagreb with a season's best score of 201.33 points. After the Warsaw Cup, Tuktamysheva decided to switch back to her Boléro short program from the previous season. At the 2016 Russian Championships, she finished eighth after placing ninth in the short and sixth in the free skate. She was named as an alternate for the 2016 European Championships.