Milian starred as the main character in the Christmas television movie for the ABC Family channel entitled "Snowglobe", alongside Lorraine Bracco. She was to be a leading character in The CW's new show "Eight Days a Week" as Olivia, alongside Mario Lopez, but The CW decided not to pick up the series due to the Writers Guild of America strike. Milian had a minor role in "Ghosts of Girlfriends Past" alongside Matthew McConaughey, and starred as the lead role in the straight-to-DVD film '. and as one of the female leads, Carmen Mendez, in the video game ' (2008).