Having satisfied its eligibility rules by possessing Italian citizenship, residing in Italy for five years, and never representing Brazil at the senior level, FIFA approved Tolói's switch of international allegiance to Italy on 17 February 2021. He was subsequently named to the Italian squad by manager Roberto Mancini on March 19, 2021, and made his debut on the 31st in the 2022 FIFA World Cup qualifier against Lithuania, playing the entire match in a 2–0 away victory.