I-122, laid down in 1925 as Submarine No. 49 and known as I-22 from her construction period until June 1938, was an of the Imperial Japanese Navy that served during the Second Sino-Japanese War and World War II. During the latter conflict, she conducted operations in support of the Japanese invasion of Malaya, the Japanese invasion of the Philippines, the bombing of Darwin, the Battle of Midway, the Guadalcanal campaign, the Battle of the Eastern Solomons, and the New Guinea campaign. She was sunk in 1945.