In 1940, during the Nazi Occupation of Poland, German authorities established a Jewish ghetto in Łowicz, in order to confine its Jewish population for the purpose of persecution and exploitation. The ghetto was liquidated in March 1941, when all its 8,000–8,200 inhabitants were transported in cattle trucks to Warsaw Ghetto, the largest ghetto in all of Nazi occupied Europe with over 400,000 Jews crammed into an area of . From there, most victims were sent to Treblinka extermination camp.