In July 2006, Vos won Event 6 at the 2006 World Series of Poker (WSOP), the . Outlasting a field of 1,919 players, Vos entered heads up action with Nam Le an almost 3:1 chip underdog. On the final hand, Vos raised to $90,000 preflop and Le made the call. The flop came and Le check-called a $150,000 bet by Vos. The turn was the and Le check-called for $250,000. The river brought the to which Le checked and Vos moved all in. Le, suspecting a bluff, made the call with , but Vos turned over for trips and the win, collecting $803,274 and the gold bracelet, becoming one of the youngest WSOP bracelet winners in history. After his victory, Vos said, "[Winning] does not really change things. I mean, it helps. But I still plan to play poker, then [in five years] I'll relax, settle down and decide what I want to do with the rest of my life." Vos cashed four times at the 2008 World Series of Poker including finishing in 80th place out of 6,844 entries in the $10,000 buy-in Main Event, earning $77,200.