Lesotho made its Paralympic debut at the 2000 Summer Paralympics in Sydney, Australia. They have entered every Summer Paralympic Games since, making Rio de Janeiro the nation's fifth appearance in a Summer Paralympiad. Lesotho had not won a Paralympic medal before the Rio de Janeiro edition. The 2016 Summer Paralympics were held from 7–18 September 2016 with a total of 4,328 athletes representing 159 National Paralympic Committees taking part. Lesotho was represented by two athletes: sprinter Sello Mothebe and discus thrower Litsitso Khotele. They were accompanied by chef de mission Lefa Moneri, team manager Makatleho Liau, deputy sports minister Marefuoe Muso, disability sports desk officer Samuel Patsa, National Paralympic Committee of Lesotho secretary-general Jobo Raswoko and coaches Sellolane Tsoaeli and Thabiso Ratsoane. Khotele was chosen to be the flag bearer during the parade of nations for the opening ceremony.