On 17 February 1943, "Easton" and sister ship sank the off Bougie in Algeria. On 10 July 1943, the Allies invaded Sicily, with "Easton" escorting convoys carrying invasion forces to Sicily. On 22 August 1943, "Easton" was part of the escort for convoy MKF22 when she detected a submarine off Pantelleria, and carried out two depth charge attacks against the submarine, and called up the Greek-manned destroyer , which carried out a third depth charge attack. The submarine, , was forced to the surface by these attacks, and then hit by gunfire by the two destroyers before being rammed by "Easton". The impact sank "U-458", with eight of the submarine's crew killed and the remaining 43 rescued. "Easton"s bow and propeller shafts were badly damaged, however, and "Easton" had to be towed into Malta by "Pindos".