She has hosted a radio (broadcast on 940 AM) and television program titled "Mujer No Estás Sola… ¡Rompe El Silencio!" (or "Woman You Are Not Alone ... Break The Silence!"). The television program, which started airing on Monday, 15 April 2019, was initially produced by the Puerto Rico Public Broadcasting Corporation and broadcast at 11:00 on WIPR-TV (San Juan) and WIPM (Mayagüez). The first episode was dedicated to Jomayra Hernández Martínez, a 13-year-old girl who was burned by her ex-boyfriend, who would die from her wounds a month later. On Monday, June 17, 2019, Vázquez Nieves hosted an episode titled "Elsie… ¡No Estás Sola!" (or "Elsie... You Are Not Alone!"), named after a mother and daughter who survived an explosion and fire in their home caused by Hurricane María. On 15 July 2020, after having dealt with 545 cases, it as announced that the show would move to WOLE-DT (Univisión Puerto Rico) and would be broadcast on the 1:30 p.m. time slot.