González served as the voluntary Director of Emergency Unit in the city of Mayagüez, helping the victims of the San Fermín earthquake. From 1919 to 1924 González was the Director of Puerto Rico's Presbyterian Hospital School of Nursing. During this time (1921), she traveled to New York and attended Columbia University. After leaving the Presbyterian Hospital she became director of the nursing at the Hospital Episcopal San Lucas (St. Lukes Hospital) in Ponce. While there she organized the nursing program and finally published her “Diccionario Medico para Enfermeras”, which she had written in 1917.