She additionally visited the areas of conflict to help tend the wounded, sustaining two hip wounds at the Battle of Seven Pines on May 31, 1862, that left her with a permanent limp. For this action she was nominated for, and later received over a century later, the Confederate Medal of Honor. During this time period, she was given the nickname "Florence Nightingale of the South". That same year, the Confederacy merged the patient load at the smaller hospitals into the larger facilities elsewhere. Wilson's Raid throughout Alabama sites in March and April 1865 forced the Hopkinses to flee the state and take refuge in Newman, Georgia.