On 28 September 2015, after a 1–5 loss to Roma, the club announced it had relieved Castori of his coaching duties with immediate effect, replacing him with Giuseppe Sannino in the first managerial change of the 2015–16 Serie A season. Carpi had achieved just two points from its opening six matches. On 3 November, the club performed a U-turn, and Castori was rehired. The club's debut top-flight season ultimately ended in relegation by a single point, with the club having found itself in a relegation dogfight from virtually the start of the season.