Takagimachi Station opened on April 10, 1928, as a station on the Miyagi Electric Railway. The line was nationalized on May 1, 1944. The station was absorbed into the JR East network upon the privatization of JNR on April 1, 1987. The station was closed from March 11 to May 28, 2011 due to damage associated with the 2011 Tōhoku earthquake and tsunami, and services beyond Takagimachi Station in the direction of Ishinomaki Station were suspended and replaced by a provisional bus rapid transit service. The station was reopened on 30 May 2015.