Following commissioning "Pawtuxet" was ordered to the Grand Banks to join the quest for the Confederate raider , but before she could get underway "Tallahassee" had returned safely to Wilmington. "Pawtuxet" was then ordered south to join the North Atlantic Blockading Squadron. Joining the 3rd Division in October she was ordered to cruise off the Carolina coast, primarily between Capes Lookout and Fear. At the end of December she bombarded the defenses at Wilmington in support of the first assault against Fort Fisher. Returning on 13 January 1865, she again turned her guns on that fort; sent men and boats to participate in the successful assault on the 15th; then resumed blockade duties. Shifted to the Virginia coast in April, she decommissioned at New York on 15 June 1865, and was sold on 15 October 1867.