At the 2006 Olympics her first distance was the 3000 metres where Wüst beat Groenewold and Cindy Klassen of Canada and became the youngest olympic champion from the Netherlands in the history of the Winter Olympics. She missed out the podium in the 1000 metres finishing fourth. At her last event the 1500 metres she won a bronze medal behind Cindy Klassen and Kristina Groves of Canada. At her last event of the season the 2006 World Allround Championships, Wüst finished fourth after she had been ill a few days before the tournament.