On the January 3, 2017 episode of "SmackDown", Ambrose defeated The Miz to win the Intercontinental Championship for the second time. He participated in the 2017 Royal Rumble match in which he lasted almost 27 minutes before being eliminated by Brock Lesnar. On February 12, Ambrose took part in the WWE Championship Elimination Chamber match at the event of the same name, where he eliminated Baron Corbin with a roll-up pin only for Corbin to attack him afterward, allowing Miz to eliminate Ambrose. A match was set between Ambrose and Corbin at the WrestleMania 33 pre-show on April 2, where Ambrose retained his Intercontinental Championship. Two nights later on "SmackDown", Ambrose wrestled in his final match for the brand, in a losing effort to Corbin in a non-title match. Following that, Ambrose was moved to the Raw brand as a result of the Superstar Shake-up. He would then continue his feud with The Miz, who was also drafted to the aforementioned brand in the Superstar Shake-up, eventually losing the Intercontinental title to him at Extreme Rules in June, thus ending his reign at 152 days. Ambrose continued to feud with The Miz, leading up to a rematch for the Intercontinental Championship at Great Balls of Fire on July 9, where he lost as a result of interference by The Miztourage (Curtis Axel and Bo Dallas).