Von Flotow was born in the village of Pitzerwitz (Pstrowice in Polish) in the region of Neumark. In 1813, he suffered a serious war injury at the Battle of Lützen, from which he never fully recovered and which led to a partial paralysis of his right arm. During a military campaign in France (1819), he took the opportunity to study lichens native to the Ardennes Mountains. In 1832 he took an early retirement from the military and worked as a private scholar in Hirschberg. Among his written works are the following: