In June 2016, Sosa wrote an op-ed in his hometown newspaper calling on the Republican presumptive presidential nominee Donald Trump to apologize for his comments on Mexican immigrants. Sosa stated that it was likely that he would leave the Republican party if Trump won the nomination at the 2016 Republican National Convention. In late August 2016, Sosa joined Gary Johnson's presidential campaign as co-chair of Hispanic outreach. Thereafter, in October 2016, Sosa changed his voting intentions to supporting Hillary Clinton's presidential campaign, as to "make a statement that Donald Trump cannot win."