In 2008, Dominguez announced that he would enter the remainder of the 2008 IndyCar Series season with Pacific Coast Motorsports, after placing third in the final Champ Car race at Long Beach. He was bumped from the field at the 2008 Indianapolis 500 and made his first true start in the series in the following race at the Milwaukee Mile. Since his 21st-place finish at Texas Motor Speedway in June, Dominguez's team skipped the next events to re-evaluate their program to be more competitive when they return. They returned on a road course only schedule and participated in the Watkins Glen, Mid-Ohio, Edmonton, and Infineon races to close out the season. His best finish of the season came at Watkins Glen in 13th place. He finished 27th in points.