In 1390, Muğla was taken over by the Ottoman Empire. However, just twelve years later, Tamerlane and his forces defeated the Ottomans in the Battle of Ankara, and returned control of the region to its former rulers, the Menteshe Beys, as he did for other Anatolian beyliks. Muğla was brought back under Ottoman control by Sultan Mehmed II the Conqueror, in 1451. One of the most important events in the area during the Ottoman period was the well-recorded campaign of Süleyman the Magnificent against Rhodes, which was launched from Marmaris.