In January 1975 Depailler was given 25–1 odds of becoming the 1975 Formula One World Champion. He finished 5th in the 1975 Argentine Grand Prix in Buenos Aires. He took 3rd at Kyalami in the 1975 South African Grand Prix. Depailler stayed behind 2nd-place finisher, Carlos Reutemann, throughout the 78 laps of the event. On the first day of qualifying for the 1975 United States Grand Prix, Depailler crashed his Tyrrell into a catch fence at Watkins Glen. He was not injured.