İnler and Udinese continued their poor form from the previous year to begin the 2010–11 Serie A campaign, losing four of their first five games, though fortunes quickly started to turn around for each. Udinese went on a streak of six-straight games without a loss, winning four in a row; in one game, İnler set up Antonio Floro Flores to level for the hosts against Cagliari, a game ending in a 1–1 draw on 7 November 2010. Following the winter break, İnler grabbed an assist in Udinese's 2–0 win over Chievo on 6 January 2011. In an enthralling game at the San Siro the next Sunday, İnler provided Antonio Di Natale with one of his goals in a 4–4 draw against eventual champions Milan. İnler then scored his first goal of the season in a 3–0 win over Cesena. The result meant that Udinese had not lost in 2011, a span of eight games, and moved up to sixth in the league table. Udinese drew their next game against Brescia before winning their next four, including a 7–0 thrashing of Palermo away from home. In the 13th and final game of their unbeaten streak, İnler scored against Catania in a 2–0 win. After finally losing, a 2–0 defeat to Lecce, İnler continued his fine run of form, scoring in a 2–1 win over title-chasers Napoli. Udinese drew with Milan on 22 May, confirming the former's fourth-place finish and Italy's final UEFA Champions League berth with one game remaining in the season.