On April 12, 2018, Edu signed a National Letter of Intent with the Toledo Rockets under head coach of Tod Kowalczyk. He played all 33 games, averaging 3.6 points, 3.9 rebounds and a team-high 1.7 blocks in 14.3 minutes per game. Edu recorded 57 blocks in the season, the most by a freshman in program history. He was named to the Mid-American Conference (MAC) All-Freshman Team. Edu missed his entire sophomore season recovering from a knee injury suffered at the 2019 FIBA Under-19 World Cup. In December 2020, AJ Edu suffered another knee injury and miss 2020-2021 NCAA season indefinitely.