Radionova made her season debut at the 2014 Japan Open where she placed first in the ladies' free skate and helped Team Europe win the gold medal. Her Grand Prix assignments were the 2014 Skate America and 2014 Trophée Éric Bompard. At Skate America, Radionova ranked second in the short program, first in the free skate, and won the gold medal by a margin of 5.85 points over compatriot Elizaveta Tuktamysheva. At the Trophée Bompard, Radionova won the gold medal and set personal best scores. She scored a total of 203.92 points, making her the first ladies' singles skater to score over 200 points this season. The results qualified Radionova for the 2014–15 Grand Prix Final. Although a fever prior to the event reduced her training time, she took the silver medal in Barcelona, finishing behind teammate Elizaveta Tuktamysheva. At the 2015 Russian Championships, she was first in both segments and won her first national title. Radionova was the silver medalist at the 2015 European Championships where she placed 1st in the short program and second in the free skate. During the 2015 World Championships, she stated that she was feeling ill and weak, having picked up a virus, but would compete anyway. Ranked second in the short program and sixth in the free skate, Radionova won the bronze medal in her world debut. She concluded her season at the 2015 World Team Trophy, placing third in the short program and second in the free skate. Both Radionova's and Tuktamysheva's efforts would aid team Russia to earn a silver medal.