On the January 17, 2017, episode of "SmackDown Live", Bliss successfully defended her title against Lynch in a steel cage match following an interference by the returning Mickie James, who aligned herself with Bliss. On February 12, Bliss dropped the title to Naomi at Elimination Chamber. On the February 21 episode of "SmackDown Live", Bliss defeated Lynch to capture the title for the second time after Naomi was forced to vacate the title due to injury, becoming the first two-time SmackDown Women's Champion. Bliss' partnership with Mickie James dissolved shortly after and the two would face off in a match on "SmackDown Live", with James defeating Bliss. On April 2, Bliss lost the title to Naomi in a six-pack challenge also involving Carmella, James, Lynch and Natalya at WrestleMania 33. Bliss and Naomi faced off in a rematch on April 4 episode of "SmackDown Live", where Bliss was once again defeated.