The "Unadilla" class was involved in numerous other operations against enemy-held territory during the war, most notably the Battle of Mobile Bay in August 1864 and the First and Second battles of Fort Fisher in December 1864 and January 1865 respectively. The main duty of the class, however, was maintenance of the blockade along the Confederate coast. While vessels of the class were too slow to catch the faster blockade runners, they nonetheless accumulated an impressive record of prizes during the war, capturing or destroying no less than 146 blockade runners during the war—almost 10% of the total number of blockade runners neutralized by the Union blockade. The most successful of the "Unadilla"s in this regard were , with 21 prizes; "Kanawha" with 19; and with 13 each; and and with 11 apiece.