Further, at the height of before-mentioned Islamic acquisitions, the growing schismatic relationship between the Latin West and Byzantine East was marked by unprecedented anti-Latin sentiment in the 11th and 12th centuries. Intensifying hostility in the 12th century to Italian trade led to anti-Roman Catholic policies and marked a changing relationship with the Western Holy Roman Empire, ultimately leading to the replacement of Latin with Greek as Byzantium’s official Imperial administrative language. The zenith of this conflict and anti-Latinism is considered a byproduct of the process of Hellenisation taking place at the time, including the Byzantine Greek Renaissance, as seen in an event known as the Massacre of the Latins in April 1182.