At club level, Galderisi played for several Italian teams throughout his career, scoring almost 200 goals across the various divisions of Italian football. A Juventus youth product, he began his professional career with the Juventus senior side, making his club debut on 20 August 1980, in a 2–2 draw against Udinese in the Coppa Italia; he made his Serie A debut with the club in a 0–0 away draw against Perugia, on 9 November 1980, his only league appearance of the 1980–81 season. Although he struggled to find the back of the net consistently with Juventus, he scored decisive goals during the 1981–82 season, including a hat-trick in Juventus's 3–2 home victory over Milan on 14 February 1982, as the Turin side captured the league title. During the 1982–83 season, he also won the Coppa Italia with Juventus and reached the 1983 European Cup Final. In total he scored 6 goals in 16 appearances for Juventus.