On the March 5 episode of "SmackDown Live", Joe, alongside Rey Mysterio and Andrade, answered United States Champion R-Truth's open challenge. Joe subsequently defeated Truth, Mysterio, and Andrade to capture the United States Championship, marking his first championship on the main roster. Joe successfully defended the title against Truth, Mysterio and Andrade at Fastlane, and against Mysterio at WrestleMania 35. On April 22, Joe was moved to Raw as part of 2019 Superstar Shake-up. At the Money in the Bank, Joe lost the title to Mysterio. On the June 3 episode of "Raw", Joe became a two-time United States Champion, after Mysterio was forced to relinquish the championship due to a separated shoulder, and handed the title to Joe, before Joe subsequently attacked Mysterio. At the Stomping Grounds, Joe lost the title to Ricochet, ending his second reign at 19 days.