Nylander is married to wife Camilla (née Altelius). He has six children: Michelle (born 1994), William (born 1996), Alexander (born 1998), Jacqueline (born 2000), Stephanie (born 2003), and Daniella (born 2006). William was drafted in 2014 by the Toronto Maple Leafs as the 8th overall pick, while Alexander was also drafted 8th overall by the Buffalo Sabres in the 2016 NHL Entry Draft. Alexander plays for the Chicago Blackhawks. Daughter Jacqueline is an aspiring professional tennis player, competing in the WTA circuit as well as collegiately at Southern Methodist University.