In 2006, Slick suffered from diverticulitis. After initial surgery, she had a relapse requiring further surgery and a tracheotomy. She was placed in an induced coma for two months and then had to learn to walk again. Also in 2006, Slick gave a speech at the inauguration of the new Virgin America airline, which named their first aircraft "Jefferson Airplane". In 2010, Slick co-wrote "Edge of Madness" with singer Michelle Mangione to raise money for remediation efforts following the BP oil spill. Grace also sang background vocals on the song and is clearly audible in the middle of the song singing, "On the edge of madness." In recent years, Slick has made sporadic appearances and has done radio interviews. She also made an appearance at the Grammy Lifetime Achievement awards in 2016.