Following the Ghouta chemical attack in August 2013 during the Syrian Civil War, Manchin said, "There is no doubt that an attack occurred and there is no doubt it was produced under the Assad regime. It's not clear cut if Assad gave the order himself. It has not been proven." He opposed any strikes on the Syrian Government in retaliation for the attacks. Instead, he introduced a joint resolution with Senator Heidi Heitkamp (D-ND) requesting that President Obama come up with a long-term strategy on Syria and work diplomatically to ensure the destruction of Syria's chemical weapons. On September 16, 2014, Manchin announced that he would vote against a possible Senate resolution to arm Syrian opposition fighters. "At the end of the day, most of the arms that we give to people are used against us. Most of the people we train turn against us," he said. He referred to plans calling for ground troops in Syria, which had been proposed by some Republican senators, including Lindsey Graham of South Carolina, as "insanity," but supported the 2017 Shayrat missile strike launched by order of President Trump in response to a chemical weapons attack allegedly perpetrated by the Syrian Government. Manchin said that "yesterday's strike was important to send a message to the Syrian regime and their Russian enablers that these horrific actions will not be tolerated."