On 7 April 2017, "Ross" and , from their positions in the Eastern Mediterranean, fired a total of 59 Tomahawk missiles at specific military targets at the Shayrat airfield in Syria. The missile barrage was in response to the death of at least 80 civilians in the immediate aftermath of 4 April 2017, Khan Shaykhun chemical attack in Idlib province, an attack that the US government concluded was launched by the Syrian regime, from Shayrat.