As a youth Samura became a companion of Muhammad. According to the history of al-Waqidi (d. 823), he fought in Muhammad's ranks at the Battle of Uhud in 627, after convincing Muhammad of his prowess when the Islamic prophet wanted to send him back to Medina due to his young age. He later participated in the Muslim conquest of Sasanian Iran (630s–640s), and was appointed the lieutenant governor of Suq al-Ahwaz in the region of Khuzistan by Abu Musa al-Ash'ari, the governor of Basra, one of the two main Arab garrison towns of Iraq.