Hananu was put under house arrest following the trial and his movements were monitored by the French intelligence. However, Hananu was released after the Great Syrian Revolt of 1925. Hananu went on to play an active role in the Syrian national movement. He was one of the founding fathers of the National Bloc which steered the course of the independence struggle in Syria until its achievement in 1946. He was a member of the National Bloc's permanent council and chief of its political bureau. In 1928, Hananu held office on the Constitutional Assembly that drafted the first republican constitution for Syria. In the 1930s, he affirmed his reputation as a hard-liner, refusing to negotiate with the French until they pledged complete unconditional independence for Syria.