On 30 November 2020, it was announced that Fittipaldi would race for Haas in the 2020 Sakhir Grand Prix, replacing the injured Romain Grosjean who was hospitalised after an accident at the 2020 Bahrain Grand Prix in which he suffered burns to his hands and ankles. This made him the first grandson of a Formula One driver to become a Formula One driver himself. Fittipaldi started his debut Grand Prix in last and finished the race 17th, the last of the remaining drivers. Haas team principal Guenther Steiner commented on Fittipaldi's debut "I think Pietro did a great job, considering he drove the car for the last time a year ago". Fittipaldi remarked that it is difficult for a driver to make it to Formula One, and he was glad to have finished his first race.