After beginning his major junior career at the early age of 15 in the Ontario Hockey League (OHL), Spezza was selected second overall in the 2001 NHL Entry Draft by the Ottawa Senators, eventually serving as their team captain following the departure of Daniel Alfredsson. Playing in the American Hockey League (AHL) in 2004–05 due to the NHL lockout, he won the Les Cunningham Award as league MVP with the Binghamton Senators. In 2005–06, Spezza set an Ottawa Senators franchise record with 71 assists, while hitting the 90-point mark for the first of two times in his NHL career.