In 1915 they were ordered overseas and departed for Salonika but en route they received order to divert to Egypt. In April 1916 the Brigade was re designated as the 22nd Mounted Brigade and attached to the Western Frontier Force and in early 1917 moved to the ANZAC Mounted Division and participated in the Second Battle of Gaza. Another move was made in June 1917, this time they were attached to the Yeomanry Mounted Division and were involved in the Third Battle of Gaza and the Battle of Beersheba, later the Division would be re designated and change their name to the 1st Mounted Division and the 4th Cavalry Division, while with the 4th Cavalry Division the Brigade again changed its designation and became the 12th Cavalry Brigade.