Between 12 December 1942 and 28 April 1943, "Earle" escorted three convoys carrying essential men and supplies to Casablanca. On her first voyage, she made two night attacks on surfaced submarines. Sailing from Norfolk on 8 June she arrived at Oran on 22 June to prepare for the invasion of Sicily, and screened the transport area off Scoglitti on 10 July. Two days later she carried on an inspection of the beach area, and then served on escort duty between north Africa ports and Sicily until 11 August when she got underway for New York, arriving the 22nd.