Parikh is known to be involved in social activities in a number of areas, partly on behalf of the foundation he founded in the nineties, the Parikh Foundation. Under the aegis of the foundation, Dr. Parikh assisted in raising monies for humanitarian relief activities for the tsunami victims of Tamil Nadu and the earthquake victims of Gujarat. He was one of delegates who accompanied President Bill Clinton on his visit of the affected areas of the Gujarat earthquake. He has also contributed towards raising of funds to spread AIDS awareness and other healthcare issues in India. He is reported to have contributed more than 2 million from his personal funds to "Share and Care Foundation", "Nargis Dutt Memorial Foundation", and the American India Foundation. He provided the corpus for a scholarship programme for the Indo American community through Share and Care Foundation during 1995 through 2005 and is a supporter of the "Ekal Vidyalaya", a tribal education programme in India.